CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: gallium atom
Accession: CHEBI:49631
browse the term
Definition: A metallic element predicted as eka-aluminium by Mendeleev in 1870 and discovered by Paul-Emile Lecoq de Boisbaudran in 1875. Named in honour of France (Latin Gallia) and perhaps also from the Latin gallus cock, a translation of Lecoq.
Synonyms: related_synonym: 31Ga; Formula=Ga; Ga; InChI=1S/Ga; InChIKey=GYHNNYVSQQEPJS-UHFFFAOYSA-N; SMILES=[Ga]; galio; gallium
alt_id: CHEBI:33326; CHEBI:49630
xref: CAS:7440-55-3
xref_mesh: MESH:D005708
xref: WebElements:Ga
G
Casp3
caspase 3
increases activity
ISO
Gallium results in increased activity of CASP3 protein
CTD
PMID:21194614
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases activity
ISO
Gallium results in increased activity of CASP8 protein
CTD
PMID:21194614
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Tf
transferrin
affects binding multiple interactions increases uptake
ISO EXP
[TF protein binds to Gallium] which binds to TFRC protein; Gallium analog binds to TF protein TFRC protein affects the uptake of [Gallium binds to TF protein] TF protein results in increased uptake of Gallium
CTD
PMID:9630424 PMID:16938349 PMID:16988841
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
G
Tfrc
transferrin receptor
affects binding multiple interactions affects uptake
ISO EXP
[TF protein binds to Gallium] which binds to TFRC protein TFRC protein affects the uptake of [Gallium binds to TF protein] TFRC protein affects the uptake of Gallium
CTD
PMID:9630424 PMID:16988841
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Abcb7
ATP binding cassette subfamily B member 7
decreases expression
ISO
gallium nitrate results in decreased expression of ABCB7 mRNA
CTD
PMID:18586083
NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858
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Aco1
aconitase 1
increases expression
ISO
gallium nitrate results in increased expression of ACO1 mRNA
CTD
PMID:18586083
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
G
Alb
albumin
multiple interactions
EXP
gallium nitrate inhibits the reaction [Tamoxifen results in decreased expression of ALB protein]
CTD
PMID:16837906
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
B2m
beta-2 microglobulin
decreases expression
ISO
gallium nitrate results in decreased expression of B2M mRNA
CTD
PMID:18586083
NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
G
Bax
BCL2 associated X, apoptosis regulator
increases expression
ISO
gallium nitrate results in increased expression of BAX protein
CTD
PMID:17121930
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
G
Calr
calreticulin
decreases expression
ISO
gallium nitrate results in decreased expression of CALR mRNA
CTD
PMID:18586083
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
G
Casp3
caspase 3
increases activity multiple interactions
ISO
gallium nitrate results in increased activity of CASP3 protein Bortezomib promotes the reaction [gallium nitrate results in increased activity of CASP3 protein]
CTD
PMID:17121930
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Cat
catalase
decreases expression
ISO
gallium nitrate results in decreased expression of CAT mRNA
CTD
PMID:18586083
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
G
Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
increases expression
ISO
gallium nitrate results in increased expression of DNAJA1 mRNA
CTD
PMID:18586083
NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
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Egr1
early growth response 1
increases expression
ISO
gallium nitrate results in increased expression of EGR1 mRNA
CTD
PMID:18586083
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Ftl1
ferritin light chain 1
increases expression
ISO
gallium nitrate results in increased expression of FTL mRNA
CTD
PMID:18586083
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
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Gpx4
glutathione peroxidase 4
decreases expression
ISO
gallium nitrate results in decreased expression of GPX4 mRNA
CTD
PMID:18586083
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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Hif1a
hypoxia inducible factor 1 subunit alpha
decreases expression
ISO
gallium nitrate results in decreased expression of HIF1A mRNA
CTD
PMID:18586083
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
ISO
gallium nitrate results in increased expression of HMOX1 mRNA; gallium nitrate results in increased expression of HMOX1 protein Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of HMOX1 mRNA]; SB 203580 inhibits the reaction [gallium nitrate results in increased expression of HMOX1 protein]
CTD
PMID:18586083
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression
ISO
gallium nitrate results in decreased expression of HSPA5 mRNA
CTD
PMID:18586083
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspa9
heat shock protein family A (Hsp70) member 9
decreases expression
ISO
gallium nitrate results in decreased expression of HSPA9 mRNA
CTD
PMID:18586083
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
G
Hspb1
heat shock protein family B (small) member 1
decreases expression
ISO
gallium nitrate results in decreased expression of HSPB1 mRNA
CTD
PMID:18586083
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Hspd1
heat shock protein family D (Hsp60) member 1
decreases expression
ISO
gallium nitrate results in decreased expression of HSPD1 mRNA
CTD
PMID:18586083
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
G
Mt2A
metallothionein 2A
multiple interactions increases expression
ISO
Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of MT2A mRNA] gallium nitrate results in increased expression of MT2A mRNA; gallium nitrate results in increased expression of MT2A protein
CTD
PMID:18586083
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mt3
metallothionein 3
increases expression
ISO
gallium nitrate results in increased expression of MT3 mRNA
CTD
PMID:18586083
NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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Mtf1
metal-regulatory transcription factor 1
increases expression
ISO
gallium nitrate results in increased expression of MTF1 mRNA
CTD
PMID:18586083
NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
gallium nitrate results in decreased expression of MYC mRNA
CTD
PMID:18586083
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions increases activity
ISO
SB 203580 inhibits the reaction [gallium nitrate results in increased activity of NFE2L2 protein]
CTD
PMID:18586083
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Popdc2
popeye domain cAMP effector 2
decreases expression
ISO
gallium nitrate results in decreased expression of POPDC2 mRNA
CTD
PMID:18586083
NCBI chr11:62,351,843...62,398,688
Ensembl chr11:62,374,759...62,390,756
G
Prdx4
peroxiredoxin 4
decreases expression
ISO
gallium nitrate results in decreased expression of PRDX4 mRNA
CTD
PMID:18586083
NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066
G
Pth
parathyroid hormone
multiple interactions
EXP
gallium nitrate inhibits the reaction [Tamoxifen results in decreased expression of PTH protein]
CTD
PMID:16837906
NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
G
Slc39a6
solute carrier family 39 member 6
decreases expression
ISO
gallium nitrate results in decreased expression of SLC39A6 mRNA
CTD
PMID:18586083
NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417
G
Slc40a1
solute carrier family 40 member 1
decreases expression
ISO
gallium nitrate results in decreased expression of SLC40A1 mRNA
CTD
PMID:18586083
NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
G
Sod1
superoxide dismutase 1
decreases expression
ISO
gallium nitrate results in decreased expression of SOD1 mRNA
CTD
PMID:18586083
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
decreases expression
ISO
gallium nitrate results in decreased expression of SOD2 mRNA
CTD
PMID:18586083
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Tf
transferrin
multiple interactions
ISO
gallium nitrate promotes the reaction [TF protein results in increased uptake of Iron]
CTD
PMID:11335103
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
G
Tfrc
transferrin receptor
decreases expression
ISO
gallium nitrate results in decreased expression of TFRC mRNA
CTD
PMID:18586083
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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