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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:copper(1+)
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Accession:CHEBI:49552 term browser browse the term
Definition:A copper cation that has formula Cu.
Synonyms:related_synonym: COPPER (I) ION;   Cu(+);   Formula=Cu;   InChI=1S/Cu/q+1;   InChIKey=VMQMZMRVKUZKQL-UHFFFAOYSA-N;   SMILES=[Cu+];   copper cation;   copper(1+) ion;   copper(I) cation;   cuprous ion
 alt_id: CHEBI:23379;   CHEBI:49551
 xref: CAS:17493-86-6;   Gmelin:15189;   PDBeChem:CU1


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copper(I) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 affects binding
multiple interactions		 ISO [Chromones analog binds to cuprous chloride] which binds to AKT1 protein
[Chromones analog binds to cuprous chloride] which results in decreased activity of AKT1 protein		 CTD PMID:16789737 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
increases expression		 ISO cuprous chloride results in increased activity of NQO1 protein
cuprous chloride results in increased expression of NQO1 mRNA		 CTD PMID:9029048 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium Chloride co-treated with cuprous chloride] binds to and affects the folding of S100A13 protein; cuprous chloride binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G Tf transferrin multiple interactions ISO cuprous chloride inhibits the reaction [TF protein results in increased uptake of Iron] CTD PMID:11335103 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        biochemical role 19556
          cofactor 16570
            copper(1+) 4
              copper(I) chloride 4
              cuprous oxide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  metal atom 18032
                    transition element atom 17576
                      d-block element atom 17571
                        copper group element atom 9722
                          copper atom 8793
                            copper molecular entity 8793
                              elemental copper 8793
                                copper cation 6351
                                  copper(1+) 4
                                    copper(I) chloride 4
                                    cuprous oxide + 0
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