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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:beryllium difluoride
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Accession:CHEBI:49499 term browser browse the term
Definition:The fluoride salt of beryllium (+2 oxidation state). In the solid state it exists as a glass, with four-coordinate Be(2+) tetrahedral centres and two-coordinate fluoride centres. As a gas it adopts a linear triatomic structure and in the liquid state a fluctuating tetrahedral structure. In protein crystallography it is used as a mimic of phosphate.
Synonyms:related_synonym: Be2F4;   BeF2;   Beryllium fluoride;   Berylliumfluorid;   Formula=BeF2;   InChI=1S/Be.2FH/h;2*1H/q+2;;/p-2;   InChIKey=JZKFIPKXQBZXMW-UHFFFAOYSA-L;   SMILES=F[Be]F
 xref: CAS:7787-49-7;   Gmelin:95146
 xref_mesh: MESH:C035982
 xref: MetaCyc:CPD0-1230;   PMID:11897645;   PMID:1551879;   PMID:16223284;   PMID:16771419;   PMID:16771420;   PMID:17963376;   PMID:17979355;   PMID:18651739;   PMID:19561071;   PMID:20529842;   PMID:20572721;   PMID:21141831;   PMID:2808407;   PMID:8800204;   Reaxys:14667390



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beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 multiple interactions ISO beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Abcc8 ATP-binding cassette, sub-family C member 8 decreases activity ISO beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960 PMID:18025464 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression EXP beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 increases phosphorylation EXP beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation EXP beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Myc myelocytomatosis oncogene increases expression EXP beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22327
    role 22313
      biological role 22312
        epitope 7188
          beryllium atom 87
            beryllium molecular entity 87
              beryllium difluoride 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 22327
    subatomic particle 22322
      composite particle 22322
        hadron 22322
          baryon 22322
            nucleon 22322
              atomic nucleus 22322
                atom 22322
                  main group element atom 22204
                    p-block element atom 22204
                      halogen 20376
                        halogen molecular entity 20376
                          halide 20355
                            halide salt 9954
                              fluoride salt 2383
                                beryllium difluoride 8
paths to the root