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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:beryllium difluoride
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Accession:CHEBI:49499 term browser browse the term
Definition:The fluoride salt of beryllium (+2 oxidation state). In the solid state it exists as a glass, with four-coordinate Be(2+) tetrahedral centres and two-coordinate fluoride centres. As a gas it adopts a linear triatomic structure and in the liquid state a fluctuating tetrahedral structure. In protein crystallography it is used as a mimic of phosphate.
Synonyms:related_synonym: Be2F4;   BeF2;   Beryllium fluoride;   Berylliumfluorid;   Formula=BeF2;   InChI=1S/Be.2FH/h;2*1H/q+2;;/p-2;   InChIKey=JZKFIPKXQBZXMW-UHFFFAOYSA-L;   SMILES=F[Be]F
 xref: CAS:7787-49-7;   Gmelin:95146
 xref_mesh: MESH:C035982
 xref: MetaCyc:CPD0-1230;   PMID:11897645;   PMID:1551879;   PMID:16223284;   PMID:16771419;   PMID:16771420;   PMID:17963376;   PMID:17979355;   PMID:18651739;   PMID:19561071;   PMID:20529842;   PMID:20572721;   PMID:21141831;   PMID:2808407;   PMID:8800204;   Reaxys:14667390


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beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases activity ISO
EXP		 beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960 PMID:18025464 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    role 19869
      biological role 19867
        epitope 7033
          beryllium atom 86
            beryllium molecular entity 86
              beryllium difluoride 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      halogen 18703
                        halogen molecular entity 18703
                          halide 18690
                            halide salt 9628
                              fluoride salt 2063
                                beryllium difluoride 8
paths to the root