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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:euxanthone
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Accession:CHEBI:4946 term browser browse the term
Definition:A member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1 and 7 and an oxo group at position 9. It has been isolated from Cratoxylum cochinchinense.
Synonyms:exact_synonym: 1,7-dihydroxy-9H-xanthen-9-one
 related_synonym: 1,7-Dihydroxyxanthone;   Formula=C13H8O4;   InChI=1S/C13H8O4/c14-7-4-5-10-8(6-7)13(16)12-9(15)2-1-3-11(12)17-10/h1-6,14-15H;   InChIKey=KDXFPEKLLFWHMN-UHFFFAOYSA-N;   SMILES=Oc1ccc2oc3cccc(O)c3c(=O)c2c1;   eyxanthone;   purrenone
 alt_id: CHEBI:67552
 xref: CAS:529-61-3;   HMDB:HMDB0030724;   KEGG:C10061;   KNApSAcK:C00002949;   KNApSAcK:C00029364
 xref_mesh: MESH:C404221
 xref: PMID:10665986;   PMID:11488451;   PMID:12451499;   PMID:16678494;   PMID:17825492;   PMID:20097048;   PMID:21428375;   Reaxys:207044


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euxanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO euxanthone inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] CTD PMID:34655103 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO euxanthone inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:34655103 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO euxanthone inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein] CTD PMID:34655103 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions ISO euxanthone inhibits the reaction [Lipopolysaccharides results in increased expression of MYD88 protein] CTD PMID:34655103 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO euxanthone inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:34655103 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            euxanthone 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  oxacycle 17903
                                    dibenzopyran 280
                                      xanthenes 274
                                        xanthones 210
                                          euxanthone 5
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