CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: quinolin-8-ol
Accession: CHEBI:48981
browse the term
Definition: A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.
Synonyms: related_synonym: 1-Azanaphthalene-8-ol; 8-Chinolinol; 8-Hydroxy-chinolin; 8-Hydroxyquinoline; 8-OQ; 8-Quinol; 8-quinolinol; Formula=C9H7NO; InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H; InChIKey=MCJGNVYPOGVAJF-UHFFFAOYSA-N; Oxyquinoline; SMILES=Oc1cccc2cccnc12
xref: CAS:148-24-3; Drug_Central:3290; KEGG:C19434; KEGG:D05321
xref_mesh: MESH:D015125
xref: MetaCyc:8-HYDROXYQUINOLINE; PDBeChem:HQY; PMID:16914038; PMID:24206710; PMID:24445658; PMID:26067700; PMID:8877786; PMID:8902522; PPDB:1354; Reaxys:114512; Wikipedia:8-Hydroxyquinoline
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Abcb5
ATP binding cassette subfamily B member 5
affects response to substance
ISO
ABCB5 gene SNP affects the susceptibility to Oxyquinoline
CTD
PMID:25622337
NCBI chr 6:139,836,528...139,932,830
Ensembl chr 6:139,835,949...139,932,830
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Abcg5
ATP binding cassette subfamily G member 5
decreases expression
ISO
Oxyquinoline results in decreased expression of ABCG5 mRNA
CTD
PMID:21632981
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Acad11
acyl-CoA dehydrogenase family, member 11
decreases expression
ISO
Oxyquinoline results in decreased expression of ACAD11 mRNA
CTD
PMID:21632981
NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
Oxyquinoline results in decreased expression of ACAT2 mRNA
CTD
PMID:21632981
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acsl3
acyl-CoA synthetase long-chain family member 3
decreases expression
ISO
Oxyquinoline results in decreased expression of ACSL3 mRNA
CTD
PMID:21632981
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acy1
aminoacylase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of ACY1 mRNA
CTD
PMID:21632981
NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression
ISO
Oxyquinoline results in decreased expression of ADH4 mRNA
CTD
PMID:21632981
NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
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Adm
adrenomedullin
decreases expression
ISO
Oxyquinoline results in decreased expression of ADM mRNA
CTD
PMID:21632981
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adss1
adenylosuccinate synthase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of ADSS1 mRNA
CTD
PMID:21632981
NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
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Aga
aspartylglucosaminidase
decreases expression
ISO
Oxyquinoline results in decreased expression of AGA mRNA
CTD
PMID:21632981
NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606
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Akr1b10
aldo-keto reductase family 1 member B10
increases expression
ISO
Oxyquinoline results in increased expression of AKR1B10 mRNA
CTD
PMID:21632981 PMID:26198647
NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
Oxyquinoline results in increased expression of AKR1C1 mRNA
CTD
PMID:21632981
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr1c2
aldo-keto reductase family 1, member C2
increases expression
ISO
Oxyquinoline results in increased expression of AKR1C2 mRNA
CTD
PMID:21632981 PMID:26198647
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Aldh1l1
aldehyde dehydrogenase 1 family, member L1
increases expression
ISO
Oxyquinoline results in increased expression of ALDH1L1 mRNA
CTD
PMID:21632981
NCBI chr 4:123,059,989...123,106,471
Ensembl chr 4:123,060,008...123,106,465
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Amdhd1
amidohydrolase domain containing 1
decreases expression
ISO
Oxyquinoline results in decreased expression of AMDHD1 mRNA
CTD
PMID:21632981
NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
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Amot
angiomotin
increases expression
ISO
Oxyquinoline results in increased expression of AMOT mRNA
CTD
PMID:21632981
NCBI chr X:108,982,399...109,041,265
Ensembl chr X:108,984,022...109,041,272
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Angptl8
angiopoietin-like 8
decreases expression
ISO
Oxyquinoline results in decreased expression of ANGPTL8 mRNA
CTD
PMID:21632981
NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
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Ankrd1
ankyrin repeat domain 1
increases expression
ISO
Oxyquinoline results in increased expression of ANKRD1 mRNA
CTD
PMID:21632981
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Ankrd37
ankyrin repeat domain 37
decreases expression
ISO
Oxyquinoline results in decreased expression of ANKRD37 mRNA
CTD
PMID:21632981
NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
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Apbb2
amyloid beta precursor protein binding family B member 2
decreases expression
ISO
Oxyquinoline results in decreased expression of APBB2 mRNA
CTD
PMID:21632981
NCBI chr14:41,557,918...41,878,622
Ensembl chr14:41,557,972...41,877,495
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Aqp3
aquaporin 3 (Gill blood group)
decreases expression
ISO
Oxyquinoline results in decreased expression of AQP3 mRNA
CTD
PMID:21632981
NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Arg1
arginase 1
increases expression
ISO
Oxyquinoline results in increased expression of ARG1 mRNA
CTD
PMID:21632981
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Arg2
arginase 2
increases expression
ISO
Oxyquinoline results in increased expression of ARG2 mRNA
CTD
PMID:21632981
NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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Arhgap44
Rho GTPase activating protein 44
decreases expression
ISO
Oxyquinoline results in decreased expression of ARHGAP44 mRNA
CTD
PMID:21632981
NCBI chr10:49,655,583...49,822,876
Ensembl chr10:49,655,584...49,824,297
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Arid3a
AT-rich interaction domain 3A
increases expression
ISO
Oxyquinoline results in increased expression of ARID3A mRNA
CTD
PMID:15612046
NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599
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Arrdc3
arrestin domain containing 3
decreases expression
ISO
Oxyquinoline results in decreased expression of ARRDC3 mRNA
CTD
PMID:21632981
NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978
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Atp6v0a2
ATPase H+ transporting V0 subunit a2
decreases expression
ISO
Oxyquinoline results in decreased expression of ATP6V0A2 mRNA
CTD
PMID:21632981
NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
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Azgp1
alpha-2-glycoprotein 1, zinc-binding
increases expression
ISO
Oxyquinoline results in increased expression of AZGP1 mRNA
CTD
PMID:21632981
NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
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Bhlhe40
basic helix-loop-helix family, member e40
decreases expression
ISO
Oxyquinoline results in decreased expression of BHLHE40 mRNA
CTD
PMID:21632981
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bmp2k
BMP-2 inducible kinase
decreases expression
ISO
Oxyquinoline results in decreased expression of BMP2K mRNA
CTD
PMID:21632981
NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
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Bpifb2
BPI fold containing family B, member 2
increases expression
ISO
Oxyquinoline results in increased expression of BPIFB2 mRNA
CTD
PMID:21632981
NCBI chr 3:142,356,990...142,377,053
Ensembl chr 3:142,358,051...142,377,044
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Carnmt1
carnosine N-methyltransferase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of CARNMT1 mRNA
CTD
PMID:21632981
NCBI chr 1:216,093,720...216,123,360
Ensembl chr 1:216,093,695...216,121,006
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Casp1
caspase 1
increases expression
ISO
Oxyquinoline results in increased expression of CASP1 mRNA
CTD
PMID:15612046
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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Ccdc18
coiled-coil domain containing 18
decreases expression
ISO
Oxyquinoline results in decreased expression of CCDC18 mRNA
CTD
PMID:21632981
NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711
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Ccn1
cellular communication network factor 1
increases expression
ISO
Oxyquinoline results in increased expression of CCN1 mRNA
CTD
PMID:21632981
NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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Ccne2
cyclin E2
decreases expression
ISO
Oxyquinoline results in decreased expression of CCNE2 mRNA
CTD
PMID:21632981
NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
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Cdc6
cell division cycle 6
decreases expression
ISO
Oxyquinoline results in decreased expression of CDC6 mRNA
CTD
PMID:21632981
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdc7
cell division cycle 7
decreases expression
ISO
Oxyquinoline results in decreased expression of CDC7 mRNA
CTD
PMID:21632981
NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
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Cdc73
cell division cycle 73
decreases expression
ISO
Oxyquinoline results in decreased expression of CDC73 mRNA
CTD
PMID:21632981
NCBI chr13:55,357,226...55,449,690
Ensembl chr13:55,357,226...55,449,656
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Cdh1
cadherin 1
decreases expression
ISO
Oxyquinoline results in decreased expression of CDH1 mRNA
CTD
PMID:21632981
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
Oxyquinoline results in increased expression of CDKN1A mRNA
CTD
PMID:21632981
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdo1
cysteine dioxygenase type 1
decreases expression
ISO
Oxyquinoline results in decreased expression of CDO1 mRNA
CTD
PMID:21632981
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Cenpk
centromere protein K
decreases expression
ISO
Oxyquinoline results in decreased expression of CENPK mRNA
CTD
PMID:21632981
NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706
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Cenps
centromere protein S
decreases expression
ISO
Oxyquinoline results in decreased expression of CENPS mRNA
CTD
PMID:21632981
NCBI chr 5:159,563,917...159,573,534
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Chac2
ChaC glutathione specific gamma-glutamylcyclotransferase 2
decreases expression
ISO
Oxyquinoline results in decreased expression of CHAC2 mRNA
CTD
PMID:21632981
NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
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Chst15
carbohydrate sulfotransferase 15
increases expression
ISO
Oxyquinoline results in increased expression of CHST15 mRNA
CTD
PMID:21632981
NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707
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Clgn
calmegin
decreases expression
ISO
Oxyquinoline results in decreased expression of CLGN mRNA
CTD
PMID:21632981
NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
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Clhc1
clathrin heavy chain linker domain containing 1
decreases expression
ISO
Oxyquinoline results in decreased expression of CLHC1 mRNA
CTD
PMID:21632981
NCBI chr14:103,288,116...103,328,725
Ensembl chr14:103,288,134...103,328,715
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Cmtr2
cap methyltransferase 2
decreases expression
ISO
Oxyquinoline results in decreased expression of CMTR2 mRNA
CTD
PMID:21632981
NCBI chr19:38,190,718...38,197,549
Ensembl chr19:38,190,642...38,197,804
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Cpa6
carboxypeptidase A6
decreases expression
ISO
Oxyquinoline results in decreased expression of CPA6 mRNA
CTD
PMID:21632981
NCBI chr 5:8,526,708...8,888,492
Ensembl chr 5:8,526,741...8,888,485
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Crebrf
CREB3 regulatory factor
increases expression
ISO
Oxyquinoline results in increased expression of CREBRF mRNA
CTD
PMID:21632981
NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
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Csad
cysteine sulfinic acid decarboxylase
decreases expression
ISO
Oxyquinoline results in decreased expression of CSAD mRNA
CTD
PMID:21632981
NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
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Csta
cystatin A
decreases expression
ISO
Oxyquinoline results in decreased expression of CSTA mRNA
CTD
PMID:21632981
NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488
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Cygb
cytoglobin
increases expression
ISO
Oxyquinoline results in increased expression of CYGB mRNA
CTD
PMID:21632981
NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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Cyp24a1
cytochrome P450, family 24, subfamily a, polypeptide 1
decreases expression
ISO
Oxyquinoline results in decreased expression of CYP24A1 mRNA
CTD
PMID:21632981
NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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Cyp51
cytochrome P450, family 51
decreases expression
ISO
Oxyquinoline results in decreased expression of CYP51A1 mRNA
CTD
PMID:21632981
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410 Ensembl chr 6:30,036,865...30,055,410
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Ddit4
DNA-damage-inducible transcript 4
decreases expression
ISO
Oxyquinoline results in decreased expression of DDIT4 mRNA
CTD
PMID:21632981
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Depp1
DEPP autophagy regulator 1
increases expression
ISO
Oxyquinoline results in increased expression of DEPP1 mRNA
CTD
PMID:21632981
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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Dmxl1
Dmx-like 1
decreases expression
ISO
Oxyquinoline results in decreased expression of DMXL1 mRNA
CTD
PMID:21632981
NCBI chr18:42,993,292...43,163,457
Ensembl chr18:42,993,340...43,163,456
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
decreases expression
ISO
Oxyquinoline results in decreased expression of DNAJB9 mRNA
CTD
PMID:21632981
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
decreases expression
ISO
Oxyquinoline results in decreased expression of DNAJC3 mRNA
CTD
PMID:21632981
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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Dram1
DNA-damage regulated autophagy modulator 1
increases expression
ISO
Oxyquinoline results in increased expression of DRAM1 mRNA
CTD
PMID:21632981
NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
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Dse
dermatan sulfate epimerase
increases expression
ISO
Oxyquinoline results in increased expression of DSE mRNA
CTD
PMID:21632981
NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
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E2f8
E2F transcription factor 8
decreases expression
ISO
Oxyquinoline results in decreased expression of E2F8 mRNA
CTD
PMID:21632981
NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
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Eed
embryonic ectoderm development
decreases expression
ISO
Oxyquinoline results in decreased expression of EED mRNA
CTD
PMID:21632981
NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
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Efcab7
EF-hand calcium binding domain 7
decreases expression
ISO
Oxyquinoline results in decreased expression of EFCAB7 mRNA
CTD
PMID:21632981
NCBI chr 5:114,525,403...114,576,130
Ensembl chr 5:114,525,167...114,576,129
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Egfr
epidermal growth factor receptor
multiple interactions
ISO
[Copper binds to Oxyquinoline] which results in increased phosphorylation of EGFR protein
CTD
PMID:18346929
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr1
early growth response 1
multiple interactions
ISO
[cupric acetate co-treated with Oxyquinoline] results in increased expression of EGR1 mRNA
CTD
PMID:10487485
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Emp3
epithelial membrane protein 3
increases expression
ISO
Oxyquinoline results in increased expression of EMP3 mRNA
CTD
PMID:21632981
NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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Eogt
EGF domain specific O-linked N-acetylglucosamine transferase
decreases expression
ISO
Oxyquinoline results in decreased expression of EOGT mRNA
CTD
PMID:21632981
NCBI chr 4:129,718,897...129,756,558
Ensembl chr 4:129,718,901...129,756,445
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Eps8l3
EPS8 like 3
increases expression
ISO
Oxyquinoline results in increased expression of EPS8L3 mRNA
CTD
PMID:21632981
NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085
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Esm1
endothelial cell-specific molecule 1
decreases expression
ISO
Oxyquinoline results in decreased expression of ESM1 mRNA
CTD
PMID:21632981
NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
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Etnppl
ethanolamine-phosphate phospho-lyase
decreases expression
ISO
Oxyquinoline results in decreased expression of ETNPPL mRNA
CTD
PMID:21632981
NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212
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Etv4
ETS variant transcription factor 4
increases expression
ISO
Oxyquinoline results in increased expression of ETV4 mRNA
CTD
PMID:21632981
NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974
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F3
coagulation factor III, tissue factor
increases expression
ISO
Oxyquinoline results in increased expression of F3 protein
CTD
PMID:25569083
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Fabp5
fatty acid binding protein 5
decreases expression
ISO
Oxyquinoline results in decreased expression of FABP5 mRNA
CTD
PMID:15612046
NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
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Fam13a
family with sequence similarity 13, member A
decreases expression
ISO
Oxyquinoline results in decreased expression of FAM13A mRNA
CTD
PMID:21632981
NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
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Fam13c
family with sequence similarity 13, member C
decreases expression
ISO
Oxyquinoline results in decreased expression of FAM13C mRNA
CTD
PMID:21632981
NCBI chr20:18,065,625...18,187,792
Ensembl chr20:18,065,628...18,187,592
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Fam241a
family with sequence similarity 241 member A
decreases expression
ISO
Oxyquinoline results in decreased expression of FAM241A mRNA
CTD
PMID:21632981
NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242
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Fdps
farnesyl diphosphate synthase
decreases expression
ISO
Oxyquinoline results in decreased expression of FDPS mRNA
CTD
PMID:21632981
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Ferry3
FERRY endosomal RAB5 effector complex subunit 3
decreases expression
ISO
Oxyquinoline results in decreased expression of FERRY3 mRNA
CTD
PMID:21632981
NCBI chr 4:159,772,693...159,809,322
Ensembl chr 4:159,772,786...159,806,382
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Filip1l
filamin A interacting protein 1-like
increases expression
ISO
Oxyquinoline results in increased expression of FILIP1L mRNA
CTD
PMID:21632981
NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415
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Fnip2
folliculin interacting protein 2
increases expression
ISO
Oxyquinoline results in increased expression of FNIP2 mRNA
CTD
PMID:21632981
NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions decreases expression
ISO
[cupric acetate co-treated with Oxyquinoline] results in increased expression of FOS mRNA Oxyquinoline results in decreased expression of FOS mRNA
CTD
PMID:10487485 PMID:21632981
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Frk
fyn-related Src family tyrosine kinase
decreases expression
ISO
Oxyquinoline results in decreased expression of FRK mRNA
CTD
PMID:21632981
NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
G
Fry
FRY microtubule binding protein
increases expression
ISO
Oxyquinoline results in increased expression of FRY mRNA
CTD
PMID:21632981
NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116
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Fxyd1
FXYD domain-containing ion transport regulator 1
increases expression
ISO
Oxyquinoline results in increased expression of FXYD1 mRNA
CTD
PMID:21632981
NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
G
G6pc1
glucose-6-phosphatase catalytic subunit 1
increases expression
ISO
Oxyquinoline results in increased expression of G6PC1 mRNA
CTD
PMID:21632981
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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Gata6
GATA binding protein 6
decreases expression
ISO
Oxyquinoline results in decreased expression of GATA6 mRNA
CTD
PMID:21632981
NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
G
Gbp2
guanylate binding protein 2
increases expression
ISO
Oxyquinoline results in increased expression of GBP2 mRNA
CTD
PMID:21632981
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
G
Gckr
glucokinase regulator
increases expression
ISO
Oxyquinoline results in increased expression of GCKR mRNA
CTD
PMID:21632981
NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
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Gcnt2
glucosaminyl (N-acetyl) transferase 2
increases expression
ISO
Oxyquinoline results in increased expression of GCNT2 mRNA
CTD
PMID:15612046
NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
G
Gdap1
ganglioside-induced differentiation-associated-protein 1
decreases expression
ISO
Oxyquinoline results in decreased expression of GDAP1 mRNA
CTD
PMID:21632981
NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061
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Gins4
GINS complex subunit 4
decreases expression
ISO
Oxyquinoline results in decreased expression of GINS4 mRNA
CTD
PMID:21632981
NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273
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Gpx8
glutathione peroxidase 8
decreases expression
ISO
Oxyquinoline results in decreased expression of GPX8 mRNA
CTD
PMID:21632981
NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195
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Grb7
growth factor receptor bound protein 7
increases expression
ISO
Oxyquinoline results in increased expression of GRB7 mRNA
CTD
PMID:21632981
NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052
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Guf1
GTP binding elongation factor GUF1
decreases expression
ISO
Oxyquinoline results in decreased expression of GUF1 mRNA
CTD
PMID:21632981
NCBI chr14:38,537,953...38,557,331
Ensembl chr14:38,537,953...38,557,331
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H2bc8
H2B clustered histone 8
decreases expression
ISO
Oxyquinoline results in decreased expression of H2BC8 mRNA
CTD
PMID:21632981
NCBI chr17:42,708,658...42,709,408
G
Hal
histidine ammonia lyase
decreases expression
ISO
Oxyquinoline results in decreased expression of HAL mRNA
CTD
PMID:21632981
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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Hamp
hepcidin antimicrobial peptide
decreases expression
ISO
Oxyquinoline results in decreased expression of HAMP mRNA
CTD
PMID:21632981
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
G
Haus3
HAUS augmin-like complex, subunit 3
decreases expression
ISO
Oxyquinoline results in decreased expression of HAUS3 mRNA
CTD
PMID:21632981
NCBI chr14:76,580,549...76,599,542
Ensembl chr14:76,580,546...76,752,463
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Heatr3
HEAT repeat containing 3
decreases expression
ISO
Oxyquinoline results in decreased expression of HEATR3 mRNA
CTD
PMID:21632981
NCBI chr19:18,892,477...18,930,502
Ensembl chr19:18,893,144...18,930,509
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Hectd2
HECT domain E3 ubiquitin protein ligase 2
decreases expression
ISO
Oxyquinoline results in decreased expression of HECTD2 mRNA
CTD
PMID:21632981
NCBI chr 1:234,274,967...234,345,598
Ensembl chr 1:234,275,705...234,343,487
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Hey1
hes-related family bHLH transcription factor with YRPW motif 1
decreases expression
ISO
Oxyquinoline results in decreased expression of HEY1 mRNA
CTD
PMID:21632981
NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
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Hilpda
hypoxia inducible lipid droplet-associated
decreases expression
ISO
Oxyquinoline results in decreased expression of HILPDA mRNA
CTD
PMID:21632981
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
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Hira
histone cell cycle regulator
decreases expression
ISO
Oxyquinoline results in decreased expression of HIRA mRNA
CTD
PMID:21632981
NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
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Hivep2
HIVEP zinc finger 2
increases expression
ISO
Oxyquinoline results in increased expression of HIVEP2 mRNA
CTD
PMID:21632981
NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
ISO
Oxyquinoline results in decreased expression of HMGCR mRNA
CTD
PMID:21632981
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmox1
heme oxygenase 1
multiple interactions decreases expression
EXP ISO
[ferric chloride co-treated with Oxyquinoline] results in decreased expression of HMOX1 mRNA; [ferric chloride co-treated with Oxyquinoline] results in decreased expression of HMOX1 protein; [ferric chloride co-treated with Oxyquinoline] results in increased expression of HMOX1 mRNA; [ferric chloride co-treated with Oxyquinoline] results in increased expression of HMOX1 protein Oxyquinoline results in decreased expression of HMOX1 mRNA
CTD
PMID:15019574 PMID:21632981
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hspa1a
heat shock protein family A (Hsp70) member 1A
increases expression affects localization
ISO
Oxyquinoline results in increased expression of HSPA1A protein Oxyquinoline affects the localization of HSPA1A protein
CTD
PMID:16239242
NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
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Hspa8
heat shock protein family A (Hsp70) member 8
affects localization
ISO
Oxyquinoline affects the localization of HSPA8 protein
CTD
PMID:16239242
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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Id3
inhibitor of DNA binding 3
decreases expression
ISO
Oxyquinoline results in decreased expression of ID3 mRNA
CTD
PMID:21632981
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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Ift70b
intraflagellar transport 70B
decreases expression
ISO
Oxyquinoline results in decreased expression of IFT70B mRNA
CTD
PMID:21632981
NCBI chr 3:60,855,809...60,858,380
Ensembl chr 3:60,855,575...60,858,389
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Igfbp1
insulin-like growth factor binding protein 1
increases expression
ISO
Oxyquinoline results in increased expression of IGFBP1 mRNA
CTD
PMID:21632981
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
G
Igfbp3
insulin-like growth factor binding protein 3
decreases expression
ISO
Oxyquinoline results in decreased expression of IGFBP3 mRNA
CTD
PMID:21632981
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Il15
interleukin 15
increases expression
ISO
Oxyquinoline results in increased expression of IL15 mRNA
CTD
PMID:15612046
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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Il6st
interleukin 6 cytokine family signal transducer
decreases expression
ISO
Oxyquinoline results in decreased expression of IL6ST mRNA
CTD
PMID:21632981
NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
G
Inhbe
inhibin subunit beta E
decreases expression
ISO
Oxyquinoline results in decreased expression of INHBE mRNA
CTD
PMID:21632981
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
G
Intu
inturned planar cell polarity protein
decreases expression
ISO
Oxyquinoline results in decreased expression of INTU mRNA
CTD
PMID:21632981
NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
G
Irak1bp1
interleukin-1 receptor-associated kinase 1 binding protein 1
decreases expression
ISO
Oxyquinoline results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:21632981
NCBI chr 8:83,731,512...83,748,289
Ensembl chr 8:83,731,507...83,748,289
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Isx
intestine-specific homeobox
increases expression
ISO
Oxyquinoline results in increased expression of ISX mRNA
CTD
PMID:21632981
NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[cupric acetate co-treated with Oxyquinoline] results in increased expression of JUN mRNA
CTD
PMID:10487485
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Katnal1
katanin catalytic subunit A1 like 1
affects response to substance
ISO
KATNAL1 gene SNP affects the susceptibility to Oxyquinoline
CTD
PMID:25622337
NCBI chr12:6,094,663...6,156,114
Ensembl chr12:6,102,836...6,157,553
G
Kbtbd8
kelch repeat and BTB domain containing 8
decreases expression
ISO
Oxyquinoline results in decreased expression of KBTBD8 mRNA
CTD
PMID:21632981
NCBI chr 4:127,675,967...127,688,785
Ensembl chr 4:127,676,141...127,687,697
G
Kctd18
potassium channel tetramerization domain containing 18
decreases expression
ISO
Oxyquinoline results in decreased expression of KCTD18 mRNA
CTD
PMID:21632981
NCBI chr 9:59,502,220...59,566,857
Ensembl chr 9:59,502,232...59,566,857
G
Kyat1
kynurenine aminotransferase 1
increases expression
ISO
Oxyquinoline results in increased expression of KYAT1 mRNA
CTD
PMID:21632981
NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
G
Laptm5
lysosomal protein transmembrane 5
increases expression
ISO
Oxyquinoline results in increased expression of LAPTM5 mRNA
CTD
PMID:15612046
NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
G
Leap2
liver enriched antimicrobial peptide 2
decreases expression
ISO
Oxyquinoline results in decreased expression of LEAP2 mRNA
CTD
PMID:21632981
NCBI chr10:37,580,172...37,581,244
Ensembl chr10:37,577,855...37,581,244
G
Lef1
lymphoid enhancer binding factor 1
decreases expression
ISO
Oxyquinoline results in decreased expression of LEF1 mRNA
CTD
PMID:15612046
NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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Lgals3
galectin 3
decreases expression
ISO
Oxyquinoline results in decreased expression of LGALS3 mRNA
CTD
PMID:21632981
NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
G
Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
Oxyquinoline results in increased expression of LIF mRNA
CTD
PMID:26198647
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lipg
lipase G, endothelial type
decreases expression
ISO
Oxyquinoline results in decreased expression of LIPG mRNA
CTD
PMID:21632981
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
G
Lox
lysyl oxidase
decreases expression
ISO
Oxyquinoline results in decreased expression of LOX mRNA
CTD
PMID:21632981
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
G
Macf1
microtubule-actin crosslinking factor 1
decreases expression
ISO
Oxyquinoline results in decreased expression of MACF1 mRNA
CTD
PMID:21632981
NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
G
Manf
mesencephalic astrocyte-derived neurotrophic factor
decreases expression
ISO
Oxyquinoline results in decreased expression of MANF mRNA
CTD
PMID:21632981
NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
G
Mapk10
mitogen activated protein kinase 10
increases expression
ISO
Oxyquinoline results in increased expression of MAPK10 mRNA
CTD
PMID:15612046
NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
G
Mastl
microtubule associated serine/threonine kinase-like
decreases expression
ISO
Oxyquinoline results in decreased expression of MASTL mRNA
CTD
PMID:21632981
NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
G
Mfsd8
major facilitator superfamily domain containing 8
decreases expression
ISO
Oxyquinoline results in decreased expression of MFSD8 mRNA
CTD
PMID:21632981
NCBI chr 2:123,822,042...123,847,808
Ensembl chr 2:123,816,614...123,857,971
G
Miga1
mitoguardin 1
decreases expression
ISO
Oxyquinoline results in decreased expression of MIGA1 mRNA
CTD
PMID:21632981
NCBI chr 2:241,224,118...241,279,174
Ensembl chr 2:241,226,015...241,279,106
G
Mixl1
Mix paired-like homeobox 1
decreases expression
ISO
Oxyquinoline results in decreased expression of MIXL1 mRNA
CTD
PMID:21632981
NCBI chr13:92,422,031...92,426,065
Ensembl chr13:92,422,031...92,426,065
G
Msmo1
methylsterol monooxygenase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of MSMO1 mRNA
CTD
PMID:21632981
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
G
Nap1l5
nucleosome assembly protein 1-like 5
decreases expression
ISO
Oxyquinoline results in decreased expression of NAP1L5 mRNA
CTD
PMID:21632981
NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654
G
Ndrg1
N-myc downstream regulated 1
increases expression
ISO
Oxyquinoline results in increased expression of NDRG1 mRNA
CTD
PMID:21632981
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
G
Neil3
nei-like DNA glycosylase 3
decreases expression
ISO
Oxyquinoline results in decreased expression of NEIL3 mRNA
CTD
PMID:21632981
NCBI chr16:38,359,305...38,418,528
Ensembl chr16:38,359,371...38,418,527
G
Nfe2l2
NFE2 like bZIP transcription factor 2
increases expression
ISO
Oxyquinoline results in increased expression of NFE2L2 mRNA
CTD
PMID:26862668
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nkx6-2
NK6 homeobox 2
increases expression
ISO
Oxyquinoline results in increased expression of NKX6-2 mRNA
CTD
PMID:15612046
NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
G
Nupr1
nuclear protein 1, transcriptional regulator
increases expression
ISO
Oxyquinoline results in increased expression of NUPR1 mRNA
CTD
PMID:21632981
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
G
Olfml3
olfactomedin-like 3
decreases expression
ISO
Oxyquinoline results in decreased expression of OLFML3 mRNA
CTD
PMID:21632981
NCBI chr 2:191,244,221...191,247,050
Ensembl chr 2:191,244,221...191,247,050
G
Osgin1
oxidative stress induced growth inhibitor 1
increases expression
ISO
Oxyquinoline results in increased expression of OSGIN1 mRNA
CTD
PMID:21632981
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
G
Pabpc1l
poly(A) binding protein, cytoplasmic 1-like
decreases expression
ISO
Oxyquinoline results in decreased expression of PABPC1L mRNA
CTD
PMID:21632981
NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997
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Pabpn1
poly(A) binding protein, nuclear 1
multiple interactions
ISO
Oxyquinoline inhibits the reaction [PABPN1 protein mutant form binds to PABPN1 protein mutant form]
CTD
PMID:16239242
NCBI chr15:28,368,100...28,372,712
Ensembl chr15:28,368,100...28,372,703
G
Palld
palladin, cytoskeletal associated protein
increases expression
ISO
Oxyquinoline results in increased expression of PALLD mRNA
CTD
PMID:21632981
NCBI chr16:28,228,006...28,621,349
Ensembl chr16:27,981,354...28,621,337
G
Paqr3
progestin and adipoQ receptor family member 3
decreases expression
ISO
Oxyquinoline results in decreased expression of PAQR3 mRNA
CTD
PMID:21632981
NCBI chr14:12,462,568...12,484,999
Ensembl chr14:12,462,563...12,479,994
G
Pck1
phosphoenolpyruvate carboxykinase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of PCK1 mRNA
CTD
PMID:21632981
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
G
PCOLCE2
procollagen C-endopeptidase enhancer 2
decreases expression
ISO
Oxyquinoline results in decreased expression of PCOLCE2 mRNA
CTD
PMID:21632981
NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
G
Pdgfrl
platelet-derived growth factor receptor-like
decreases expression
ISO
Oxyquinoline results in decreased expression of PDGFRL mRNA
CTD
PMID:21632981
NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
G
Pdk1
pyruvate dehydrogenase kinase 1
decreases expression
ISO
Oxyquinoline results in decreased expression of PDK1 mRNA
CTD
PMID:21632981
NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
G
Pdp2
pyruvate dehydrogenase phosphatase catalytic subunit 2
decreases expression
ISO
Oxyquinoline results in decreased expression of PDP2 mRNA
CTD
PMID:21632981
NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
G
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
decreases expression
ISO
Oxyquinoline results in decreased expression of PFKFB3 mRNA
CTD
PMID:21632981
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
G
Pgc
progastricsin
increases expression
ISO
Oxyquinoline results in increased expression of PGC mRNA
CTD
PMID:21632981
NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682
G
Pigw
phosphatidylinositol glycan anchor biosynthesis, class W
decreases expression
ISO
Oxyquinoline results in decreased expression of PIGW mRNA
CTD
PMID:21632981
NCBI chr10:69,746,996...69,782,656
Ensembl chr10:69,748,789...69,790,475
G
Plac8
placenta associated 8
decreases expression
ISO
Oxyquinoline results in decreased expression of PLAC8 mRNA
CTD
PMID:21632981
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
G
Plin2
perilipin 2
decreases expression
ISO
Oxyquinoline results in decreased expression of PLIN2 mRNA
CTD
PMID:21632981
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Plk2
polo-like kinase 2
increases expression
ISO
Oxyquinoline results in increased expression of PLK2 mRNA
CTD
PMID:21632981
NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
G
Plp1
proteolipid protein 1
decreases expression
ISO
Oxyquinoline results in decreased expression of PLP1 mRNA
CTD
PMID:21632981
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
G
Plppr1
phospholipid phosphatase related 1
increases expression
ISO
Oxyquinoline results in increased expression of PLPPR1 mRNA
CTD
PMID:21632981
NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
G
Ppp1r16a
protein phosphatase 1, regulatory subunit 16A
increases expression
ISO
Oxyquinoline results in increased expression of PPP1R16A mRNA
CTD
PMID:21632981
NCBI chr 7:108,391,664...108,414,812
Ensembl chr 7:108,391,656...108,419,509
G
Ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
decreases expression
ISO
Oxyquinoline results in decreased expression of PPP1R1C mRNA
CTD
PMID:15612046
NCBI chr 3:64,616,700...64,719,696
Ensembl chr 3:64,616,700...64,724,104
G
Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
decreases expression
ISO
Oxyquinoline results in decreased expression of PPP1R3C mRNA
CTD
PMID:21632981
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
G
Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha
decreases expression
ISO
Oxyquinoline results in decreased expression of PPP3R1 mRNA
CTD
PMID:21632981
NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
G
Prorsd1
prolyl-tRNA synthetase associated domain containing 1
decreases expression
ISO
Oxyquinoline results in decreased expression of PRORSD1P mRNA
CTD
PMID:21632981
NCBI chr14:103,257,979...103,260,248
Ensembl chr14:103,257,979...103,260,248
G
Ptcd2
pentatricopeptide repeat domain 2
decreases expression
ISO
Oxyquinoline results in decreased expression of PTCD2 mRNA
CTD
PMID:21632981
NCBI chr 2:30,712,276...30,739,968
Ensembl chr 2:30,712,280...30,739,942
G
Ptchd4
patched domain containing 4
increases expression
ISO
Oxyquinoline results in increased expression of PTCHD4 mRNA
CTD
PMID:21632981
NCBI chr 9:18,462,934...18,666,272
Ensembl chr 9:18,463,737...18,665,705
G
Ptms
parathymosin
increases expression
ISO
Oxyquinoline results in increased expression of PTMS mRNA
CTD
PMID:21632981
NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
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Qpct
glutaminyl-peptide cyclotransferase
decreases expression
ISO
Oxyquinoline results in decreased expression of QPCT mRNA
CTD
PMID:21632981
NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711
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Rabgap1l
RAB GTPase activating protein 1-like
decreases expression
ISO
Oxyquinoline results in decreased expression of RABGAP1L mRNA
CTD
PMID:21632981
NCBI chr13:72,464,114...73,059,845
Ensembl chr13:72,468,110...73,059,984
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Radx
RPA1 related single stranded DNA binding protein, X-linked
decreases expression
ISO
Oxyquinoline results in decreased expression of RADX mRNA
CTD
PMID:21632981
NCBI chr X:103,089,284...103,176,840
Ensembl chr X:103,089,284...103,176,838
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Rag1
recombination activating 1
decreases expression
ISO
Oxyquinoline results in decreased expression of RAG1 mRNA
CTD
PMID:15612046
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
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Rbm24
RNA binding motif protein 24
increases expression
ISO
Oxyquinoline results in increased expression of RBM24 mRNA
CTD
PMID:21632981
NCBI chr17:18,275,681...18,288,231
Ensembl chr17:18,275,688...18,288,102
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Reep3
receptor accessory protein 3
decreases expression
ISO
Oxyquinoline results in decreased expression of REEP3 mRNA
CTD
PMID:21632981
NCBI chr20:21,493,868...21,578,698
Ensembl chr20:21,493,954...21,578,697
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Rgcc
regulator of cell cycle
increases expression
ISO
Oxyquinoline results in increased expression of RGCC mRNA
CTD
PMID:21632981
NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
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Rnft1
ring finger protein, transmembrane 1
decreases expression
ISO
Oxyquinoline results in decreased expression of RNFT1 mRNA
CTD
PMID:21632981
NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778
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Rpgrip1l
Rpgrip1-like
decreases expression
ISO
Oxyquinoline results in decreased expression of RPGRIP1L mRNA
CTD
PMID:21632981
NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083
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Rsl1d1
ribosomal L1 domain containing 1
increases expression
ISO
Oxyquinoline results in increased expression of RSL1D1 mRNA
CTD
PMID:21632981
NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
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Sdf2l1
stromal cell-derived factor 2-like 1
decreases expression
ISO
Oxyquinoline results in decreased expression of SDF2L1 mRNA
CTD
PMID:21632981
NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902
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Senp5
SUMO specific peptidase 5
decreases expression
ISO
Oxyquinoline results in decreased expression of SENP5 mRNA
CTD
PMID:21632981
NCBI chr11:68,784,699...68,819,569
Ensembl chr11:68,784,957...68,819,562
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Serpina7
serpin family A member 7
increases expression
ISO
Oxyquinoline results in increased expression of SERPINA7 mRNA
CTD
PMID:21632981
NCBI chr X:102,663,242...102,722,319
Ensembl chr X:102,663,405...102,669,040
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Serpine1
serpin family E member 1
decreases expression
ISO
Oxyquinoline results in decreased expression of SERPINE1 mRNA
CTD
PMID:21632981
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Sgk2
serum/glucocorticoid regulated kinase 2
decreases expression
ISO
Oxyquinoline results in decreased expression of SGK2 mRNA
CTD
PMID:21632981
NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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Slc16a6
solute carrier family 16, member 6
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC16A6 mRNA
CTD
PMID:21632981
NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
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Slc22a3
solute carrier family 22 member 3
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC22A3 mRNA
CTD
PMID:21632981
NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
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Slc30a1
solute carrier family 30 member 1
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC30A1 mRNA
CTD
PMID:21632981
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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Slc30a10
solute carrier family 30, member 10
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC30A10 mRNA
CTD
PMID:21632981
NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103
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Slc35b3
solute carrier family 35 member B3
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC35B3 mRNA
CTD
PMID:21632981
NCBI chr17:25,846,590...25,873,115
Ensembl chr17:25,846,748...25,872,557
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Slc35d1
solute carrier family 35 member D1
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC35D1 mRNA
CTD
PMID:21632981
NCBI chr 5:117,928,628...117,981,289
Ensembl chr 5:117,934,352...117,981,311
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Slc51a
solute carrier family 51 member A
decreases expression
ISO
Oxyquinoline results in decreased expression of SLC51A mRNA
CTD
PMID:21632981
NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
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Slco4a1
solute carrier organic anion transporter family, member 4a1
increases expression
ISO
Oxyquinoline results in increased expression of SLCO4A1 mRNA
CTD
PMID:21632981
NCBI chr 3:167,559,177...167,578,307
Ensembl chr 3:167,559,316...167,578,305
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Slf1
SMC5-SMC6 complex localization factor 1
decreases expression
ISO
Oxyquinoline results in decreased expression of SLF1 mRNA
CTD
PMID:21632981
NCBI chr 2:6,767,015...6,874,428
Ensembl chr 2:6,767,015...6,867,149
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Smim13
small integral membrane protein 13
decreases expression
ISO
Oxyquinoline results in decreased expression of SMIM13 mRNA
CTD
PMID:21632981
NCBI chr17:23,497,662...23,515,705
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Snu13
small nuclear ribonucleoprotein 13
decreases expression
ISO
Oxyquinoline results in decreased expression of SNU13 mRNA
CTD
PMID:15612046
NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872 Ensembl chr 1:113,565,295...113,570,872
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Sod2
superoxide dismutase 2
multiple interactions
EXP
[ferric chloride co-treated with Oxyquinoline] results in decreased expression of SOD2 protein; [ferric chloride co-treated with Oxyquinoline] results in increased expression of SOD2 mRNA; [ferric chloride co-treated with Oxyquinoline] results in increased expression of SOD2 protein
CTD
PMID:15019574
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sorbs3
sorbin and SH3 domain containing 3
increases expression
ISO
Oxyquinoline results in increased expression of SORBS3 mRNA
CTD
PMID:21632981
NCBI chr15:45,252,921...45,284,758
Ensembl chr15:45,253,379...45,284,758
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Spa17
sperm autoantigenic protein 17
decreases expression
ISO
Oxyquinoline results in decreased expression of SPA17 mRNA
CTD
PMID:21632981
NCBI chr 8:37,307,432...37,318,519
Ensembl chr 8:37,307,557...37,318,639
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Spag4
sperm associated antigen 4
decreases expression
ISO
Oxyquinoline results in decreased expression of SPAG4 mRNA
CTD
PMID:21632981
NCBI chr 3:144,581,006...144,587,879
Ensembl chr 3:144,581,095...144,585,435
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Spc25
SPC25 component of NDC80 kinetochore complex
decreases expression
ISO
Oxyquinoline results in decreased expression of SPC25 mRNA
CTD
PMID:21632981
NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
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Spin4
spindlin family, member 4
decreases expression
ISO
Oxyquinoline results in decreased expression of SPIN4 mRNA
CTD
PMID:21632981
NCBI chr X:59,888,728...59,892,817
Ensembl chr X:59,891,581...59,892,330
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Spon2
spondin 2
increases expression
ISO
Oxyquinoline results in increased expression of SPON2 mRNA
CTD
PMID:21632981
NCBI chr14:77,505,695...77,518,001
Ensembl chr14:77,511,901...77,517,996
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Srd5a3
steroid 5 alpha-reductase 3
decreases expression
ISO
Oxyquinoline results in decreased expression of SRD5A3 mRNA
CTD
PMID:21632981
NCBI chr14:32,046,408...32,060,796
Ensembl chr14:32,046,408...32,060,747
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Srxn1
sulfiredoxin 1
increases expression
ISO
Oxyquinoline results in increased expression of SRXN1 mRNA
CTD
PMID:21632981
NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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Ssuh2
ssu-2 homolog
increases expression
ISO
Oxyquinoline results in increased expression of SSUH2 mRNA
CTD
PMID:21632981
NCBI chr 4:145,502,942...145,521,881
Ensembl chr 4:145,503,185...145,521,735
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Stil
STIL, centriolar assembly protein
decreases expression
ISO
Oxyquinoline results in decreased expression of STIL mRNA
CTD
PMID:21632981
NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
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Stom
stomatin
increases expression
ISO
Oxyquinoline results in increased expression of STOM mRNA
CTD
PMID:21632981
NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354
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Sult2a1
sulfotransferase family 2A member 1
increases expression
ISO
Oxyquinoline results in increased expression of SULT2A1 mRNA
CTD
PMID:21632981
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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Tcfl5
transcription factor like 5
increases expression
ISO
Oxyquinoline results in increased expression of TCFL5 mRNA
CTD
PMID:15612046
NCBI chr 3:167,734,471...167,754,174
Ensembl chr 3:167,734,473...167,754,282
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Tex9
testis expressed 9
decreases expression
ISO
Oxyquinoline results in decreased expression of TEX9 mRNA
CTD
PMID:21632981
NCBI chr 8:73,168,519...73,213,935
Ensembl chr 8:73,177,810...73,214,261
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Thap2
THAP domain containing 2
increases expression
ISO
Oxyquinoline results in increased expression of THAP2 mRNA
CTD
PMID:21632981
NCBI chr 7:50,992,912...51,007,582
Ensembl chr 7:50,995,793...51,008,061
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Timm8a1
translocase of inner mitochondrial membrane 8A1
decreases expression
ISO
Oxyquinoline results in decreased expression of TIMM8A mRNA
CTD
PMID:21632981
NCBI chr X:97,717,932...97,722,170
Ensembl chr X:97,717,920...97,721,960
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Tm7sf2
transmembrane 7 superfamily member 2
decreases expression
ISO
Oxyquinoline results in decreased expression of TM7SF2 mRNA
CTD
PMID:21632981
NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
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Tmcc1
transmembrane and coiled-coil domain family 1
increases expression
ISO
Oxyquinoline results in increased expression of TMCC1 mRNA
CTD
PMID:21632981
NCBI chr 4:149,069,252...149,239,585
Ensembl chr 4:149,069,260...149,239,620
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Tmem116
transmembrane protein 116
decreases expression
ISO
Oxyquinoline results in decreased expression of TMEM116 mRNA
CTD
PMID:21632981
NCBI chr12:35,021,912...35,089,409
Ensembl chr12:35,041,572...35,089,430
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Tmem128
transmembrane protein 128
decreases expression
ISO
Oxyquinoline results in decreased expression of TMEM128 mRNA
CTD
PMID:21632981
NCBI chr14:72,539,530...72,548,623
Ensembl chr14:72,539,532...72,548,550
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Oxyquinoline results in increased expression of TNFAIP3 mRNA
CTD
PMID:21632981
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfsf10
TNF superfamily member 10
increases expression
ISO
Oxyquinoline results in increased expression of TNFSF10 mRNA
CTD
PMID:21632981
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tp63
tumor protein p63
increases expression
ISO
Oxyquinoline results in increased expression of TRP63 mRNA
CTD
PMID:15612046
NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
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Trpv2
transient receptor potential cation channel, subfamily V, member 2
increases expression
ISO
Oxyquinoline results in increased expression of TRPV2 mRNA
CTD
PMID:15612046
NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
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Ttr
transthyretin
increases expression
ISO
Oxyquinoline results in increased expression of TTR mRNA
CTD
PMID:21632981
NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Ttyh3
tweety family member 3
increases expression
ISO
Oxyquinoline results in increased expression of TTYH3 mRNA
CTD
PMID:21632981
NCBI chr12:13,996,831...14,025,457
Ensembl chr12:13,997,045...14,025,459
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Tuba1a
tubulin, alpha 1A
decreases expression
ISO
Oxyquinoline results in decreased expression of TUBA1A mRNA
CTD
PMID:21632981
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
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Tubb1
tubulin, beta 1 class VI
affects expression
ISO
Oxyquinoline affects the expression of TUBB1 mRNA
CTD
PMID:21632981
NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
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Tube1
tubulin, epsilon 1
decreases expression
ISO
Oxyquinoline results in decreased expression of TUBE1 mRNA
CTD
PMID:21632981
NCBI chr20:42,552,390...42,570,324
Ensembl chr20:42,552,437...42,570,314
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Txnip
thioredoxin interacting protein
increases expression
ISO
Oxyquinoline results in increased expression of TXNIP mRNA
CTD
PMID:21632981
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Ubd
ubiquitin D
increases expression
ISO
Oxyquinoline results in increased expression of UBD mRNA
CTD
PMID:21632981
NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639 Ensembl chr20:1,385,864...1,408,639
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Ugt2b15
UDP glucuronosyltransferase family 2 member B15
increases metabolic processing
EXP
UGT2B15 protein results in increased metabolism of Oxyquinoline
CTD
PMID:7574722
NCBI chr14:20,768,015...20,783,599
Ensembl chr14:20,768,015...20,783,589
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Usp43
ubiquitin specific peptidase 43
decreases expression
ISO
Oxyquinoline results in decreased expression of USP43 mRNA
CTD
PMID:21632981
NCBI chr10:52,549,200...52,611,168
Ensembl chr10:52,548,963...52,611,533
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Utrn
utrophin
increases expression
ISO
Oxyquinoline results in increased expression of UTRN mRNA
CTD
PMID:21632981
NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313
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Ypel3
yippee-like 3
increases expression
ISO
Oxyquinoline results in increased expression of YPEL3 mRNA
CTD
PMID:21632981
NCBI chr 1:181,384,385...181,387,706
Ensembl chr 1:181,384,357...181,387,705
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Zbtb38
zinc finger and BTB domain containing 38
increases expression
ISO
Oxyquinoline results in increased expression of ZBTB38 mRNA
CTD
PMID:21632981
NCBI chr 8:97,284,617...97,288,518
Ensembl chr 8:97,280,993...97,485,625
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Zbtb8a
zinc finger and BTB domain containing 8a
decreases expression
ISO
Oxyquinoline results in decreased expression of ZBTB8A mRNA
CTD
PMID:21632981
NCBI chr 5:141,693,189...141,721,464
Ensembl chr 5:141,693,189...141,721,344
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Zwint
ZW10 interacting kinetochore protein
decreases expression
ISO
Oxyquinoline results in decreased expression of ZWINT mRNA
CTD
PMID:21632981
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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