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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:benzotriazoles
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Accession:CHEBI:48912 term browser browse the term



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1-aminobenzotriazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of ACAT1 protein] CTD PMID:32435916 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Chlorpyrifos metabolite results in decreased activity of ACHE protein] CTD PMID:30625376 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ACOT2 protein] CTD PMID:32435916 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ALDH1B1 protein] CTD PMID:32435916 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CAR3 protein] CTD PMID:32435916 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Benzo(a)pyrene results in increased expression of CD86 protein] CTD PMID:21742781 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Ces3a carboxylesterase 3a multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of CES3B protein] CTD PMID:32435916 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]
1-aminobenzotriazole results in increased expression of CYP1A1 protein
1-aminobenzotriazole inhibits the reaction [Oxygen results in increased activity of CYP1A1 protein]; [1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A1 protein
CTD PMID:10640292 PMID:20187624 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases activity
multiple interactions
EXP
ISO
1-aminobenzotriazole results in increased expression of CYP1A2 protein
1-aminobenzotriazole results in decreased activity of CYP1A2 protein
[1-aminobenzotriazole co-treated with Oxygen] results in increased activity of CYP1A2 protein; [Oxygen co-treated with 1-aminobenzotriazole] results in increased expression of CYP1A2 protein
CTD PMID:10640292 PMID:15618748 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases activity
ISO 1-aminobenzotriazole inhibits the reaction [CYP2D6 protein results in increased hydroxylation of bufuralol]
1-aminobenzotriazole results in decreased activity of CYP2D6 protein
CTD PMID:11375247 PMID:15618748 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO 1-aminobenzotriazole results in decreased activity of CYP2E1 protein
1-aminobenzotriazole inhibits the reaction [CYP2E1 protein affects the metabolism of Urethane]; 1-aminobenzotriazole inhibits the reaction [CYP2E1 protein results in increased oxidation of 1,3-butadiene]
1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene]
CTD PMID:10828257 PMID:12704224 PMID:15618748 PMID:25243916 PMID:27421776 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO 1-aminobenzotriazole results in decreased activity of CYP3A4 protein CTD PMID:11375247 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Beclomethasone results in increased expression of CYP3A5 mRNA] CTD PMID:24555085 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Ech1 enoyl-CoA hydratase 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of ECH1 protein] CTD PMID:32435916 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of FTCD protein] CTD PMID:32435916 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased expression of FTH1 protein] CTD PMID:32435916 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of FTL1 protein] CTD PMID:32435916 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; 1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [1-aminobenzotriazole co-treated with ochratoxin A] results in increased activity of GPT protein; [Emodin co-treated with 1-aminobenzotriazole] results in increased expression of GPT protein CTD PMID:25900201 PMID:34492313 PMID:36227364 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in increased expression of GSTM1 protein] CTD PMID:32435916 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [captax results in increased expression of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; 1-aminobenzotriazole inhibits the reaction [Trichloroethylene results in increased phosphorylation of H2AX protein] CTD PMID:28300663 PMID:29722447 PMID:35279910 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of HAVCR1 protein CTD PMID:36227364 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [[Acetaminophen co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Butylated Hydroxyanisole co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Diclofenac co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA]; 1-aminobenzotriazole inhibits the reaction [[Ticlopidine co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA] CTD PMID:18227147 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Inmt indolethylamine N-methyltransferase multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of INMT protein] CTD PMID:32435916 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Krt8 keratin 8 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of KRT8 protein] CTD PMID:32435916 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lcn2 lipocalin 2 multiple interactions ISO [1-aminobenzotriazole co-treated with ochratoxin A] results in increased expression of LCN2 protein CTD PMID:36227364 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Rgn regucalcin multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of RGN protein] CTD PMID:32435916 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO 1-aminobenzotriazole inhibits the reaction [[[SULT1A1 protein co-treated with CYP2E1 protein] results in increased susceptibility to 1-methylpyrene] which results in increased mutagenesis of HPRT1 gene] CTD PMID:25243916 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Ubp1 upstream binding protein 1 multiple interactions ISO 1-aminobenzotriazole affects the reaction [propylene dichloride results in decreased expression of UBP1 protein] CTD PMID:32435916 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625
JBrowse link
4,5,6,7-TETRABROMOBENZOTRIAZOLE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC mRNA]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC protein] CTD PMID:26301327 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased expression of BAX protein CTD PMID:16489027 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein CTD PMID:16489027 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in decreased expression of BCL2L1 protein CTD PMID:16489027 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to FOS promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC mRNA]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of ARC protein]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of FOS mRNA]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased phosphorylation of BRD4 protein] CTD PMID:26301327 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to ARC promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to FOS promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased phosphorylation of BRD4 protein] CTD PMID:26301327 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:16489027 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased activity of CASP8 protein CTD PMID:16489027 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:16489027 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]] CTD PMID:22317921 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [Rotenone results in increased expression of DNM1L protein] CTD PMID:37156403 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Fgf14 fibroblast growth factor 14 multiple interactions EXP 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [FGF14 protein binds to SCN2A protein]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [FGF14 protein binds to SCN8A protein]; 4,5,6,7-tetrabromobenzotriazole results in decreased expression of and affects the localization of FGF14 protein CTD PMID:26917740 NCBI chr15:101,045,033...101,679,888
Ensembl chr15:101,045,036...101,679,900
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to FOS promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of FOS mRNA] CTD PMID:26301327 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [Acrylamide results in decreased activity of IKZF1 protein] CTD PMID:20708675 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein] CTD PMID:37156403 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein promotes the reaction [BRD4 protein binds to NR4A1 promoter]]; 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [BDNF protein results in increased expression of NR4A1 mRNA] CTD PMID:26301327 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [Rotenone results in increased expression of PINK1 protein] CTD PMID:37156403 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [Rotenone results in increased expression of PRKN protein] CTD PMID:37156403 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 multiple interactions EXP 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [FGF14 protein binds to SCN2A protein] CTD PMID:26917740 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [FGF14 protein binds to SCN8A protein] CTD PMID:26917740 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292
JBrowse link
G Slc39a7 solute carrier family 39 member 7 multiple interactions ISO 4,5,6,7-tetrabromobenzotriazole inhibits the reaction [[Zinc co-treated with pyrithione] promotes the reaction [CSNK2A1 protein binds to SLC39A7 protein]] CTD PMID:22317921 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in decreased expression of BCL2 protein; [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in decreased expression of BCL2L1 protein; [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP9 protein; [4,5,6,7-tetrabromobenzotriazole co-treated with TNFSF10 protein] results in increased expression of BAX protein CTD PMID:16489027 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 affects binding
multiple interactions
EXP alizapride binds to DRD2 protein
alizapride binds to and results in decreased activity of DRD2 protein
CTD PMID:2571179 PMID:2901473 PMID:8103596 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
benzotriazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP benzotriazole results in increased expression of GSTA2 mRNA CTD PMID:8951341 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP benzotriazole results in increased expression of GSTA3 mRNA CTD PMID:8951341 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP benzotriazole results in increased expression of GSTA5 mRNA CTD PMID:8951341 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP benzotriazole results in increased expression of GSTM1 mRNA CTD PMID:8951341 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
vorozole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 affects binding ISO vorozole analog binds to CYP19A1 protein CTD PMID:9720668 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO vorozole results in increased activity of CYP1A1 protein CTD PMID:16714371 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19880
    chemical entity 19878
      atom 19878
        nonmetal atom 19800
          nitrogen atom 18979
            nitrogen molecular entity 18979
              organonitrogen compound 18833
                organonitrogen heterocyclic compound 18153
                  benzotriazoles 57
                    1-(1-benzotriazolyl)-3-(2-methylphenoxy)-2-propanol 0
                    1-(2,4-dichlorobenzoyl)-1H-1,2,3-benzotriazole 0
                    1-Hydroxybenzotriazole 0
                    1-[(2,4-dichlorophenyl)methoxy]benzotriazole 0
                    1-[1-[[1-[(4-methylphenyl)methyl]-5-tetrazolyl]methyl]-4-piperidinyl]-5-(trifluoromethyl)benzotriazole 0
                    1-[[2-(1-benzotriazolyl)-1-oxoethyl]amino]-3-cyclohexylthiourea 0
                    1-aminobenzotriazole 30
                    1-propan-2-yl-5-benzotriazolecarboxylic acid 0
                    2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide 0
                    2-(1H-1,2,3-benzotriazol-1-yl)-N-(2,3-dihydro-1H-inden-2-yl)acetamide 0
                    2-[(6-chloro-1-benzotriazolyl)oxy]-N-(4-fluorophenyl)acetamide 0
                    2-[[5-(1-benzotriazolylmethyl)-1,3,4-oxadiazol-2-yl]thio]-N-[(4-fluorophenyl)methyl]-N-phenylacetamide 0
                    2-amino-5-(1-benzotriazolyl)-6-methyl-4-phenyl-4H-pyran-3-carbonitrile 0
                    3-(1-benzotriazolyl)-N'-[(3-methoxy-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]propanehydrazide 0
                    3-(1-benzotriazolylmethyl)-6-(2-phenylethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                    3-(1-benzotriazolylmethyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                    3-(1-benzotriazolylmethyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                    4,5,6,7-TETRABROMOBENZOTRIAZOLE 22
                    4-Methylbenzotriazole 0
                    5-(Trifluoromethyl)-1H-1,2,3-benzotriazole 0
                    5-fluoro-1-[1-[[1-(2-phenylethyl)-5-tetrazolyl]methyl]-4-piperidinyl]benzotriazole 0
                    5-methyl-1H-benzotriazole 0
                    6-Chloro-5-methyl-1H-1,2,3-benzotriazole 0
                    6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide 1
                    N-(4-\{[(1H-benzotriazol-1-yl)acetyl][(thiophen-3-yl)methyl]amino\}phenyl)propanamide 0
                    N-\{4-[(1H-benzotriazol-1-ylacetyl)(thiophen-3-ylmethyl)amino]phenyl\}-2-methylpropanamide 0
                    [\{4-[(2R,4E)-2-(1,3-benzothiazol-2-yl)-2-(1H-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl\}(difluoro)methyl]phosphonic acid 0
                    benzotriazole + 4
                    methyl 1-isopropyl-1H-1,2,3-benzotriazole-5-carboxylate 0
                    vorozole 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      p-block molecular entity 19817
                        carbon group molecular entity 19757
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18300
                                    organic heterobicyclic compound 17242
                                      benzotriazoles 57
                                        1-(1-benzotriazolyl)-3-(2-methylphenoxy)-2-propanol 0
                                        1-(2,4-dichlorobenzoyl)-1H-1,2,3-benzotriazole 0
                                        1-Hydroxybenzotriazole 0
                                        1-[(2,4-dichlorophenyl)methoxy]benzotriazole 0
                                        1-[1-[[1-[(4-methylphenyl)methyl]-5-tetrazolyl]methyl]-4-piperidinyl]-5-(trifluoromethyl)benzotriazole 0
                                        1-[[2-(1-benzotriazolyl)-1-oxoethyl]amino]-3-cyclohexylthiourea 0
                                        1-aminobenzotriazole 30
                                        1-propan-2-yl-5-benzotriazolecarboxylic acid 0
                                        2-(1H-1,2,3-Benzotriazol-1-yl)-N'-(3,4,5-trimethoxybenzylidene)acetohydrazide 0
                                        2-(1H-1,2,3-benzotriazol-1-yl)-N-(2,3-dihydro-1H-inden-2-yl)acetamide 0
                                        2-[(6-chloro-1-benzotriazolyl)oxy]-N-(4-fluorophenyl)acetamide 0
                                        2-[[5-(1-benzotriazolylmethyl)-1,3,4-oxadiazol-2-yl]thio]-N-[(4-fluorophenyl)methyl]-N-phenylacetamide 0
                                        2-amino-5-(1-benzotriazolyl)-6-methyl-4-phenyl-4H-pyran-3-carbonitrile 0
                                        3-(1-benzotriazolyl)-N'-[(3-methoxy-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]propanehydrazide 0
                                        3-(1-benzotriazolylmethyl)-6-(2-phenylethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                                        3-(1-benzotriazolylmethyl)-6-phenyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                                        3-(1-benzotriazolylmethyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole 0
                                        4,5,6,7-TETRABROMOBENZOTRIAZOLE 22
                                        4-Methylbenzotriazole 0
                                        5-(Trifluoromethyl)-1H-1,2,3-benzotriazole 0
                                        5-fluoro-1-[1-[[1-(2-phenylethyl)-5-tetrazolyl]methyl]-4-piperidinyl]benzotriazole 0
                                        5-methyl-1H-benzotriazole 0
                                        6-Chloro-5-methyl-1H-1,2,3-benzotriazole 0
                                        6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide 1
                                        N-(4-\{[(1H-benzotriazol-1-yl)acetyl][(thiophen-3-yl)methyl]amino\}phenyl)propanamide 0
                                        N-\{4-[(1H-benzotriazol-1-ylacetyl)(thiophen-3-ylmethyl)amino]phenyl\}-2-methylpropanamide 0
                                        [\{4-[(2R,4E)-2-(1,3-benzothiazol-2-yl)-2-(1H-benzotriazol-1-yl)-5-phenylpent-4-en-1-yl]phenyl\}(difluoro)methyl]phosphonic acid 0
                                        benzotriazole + 4
                                        methyl 1-isopropyl-1H-1,2,3-benzotriazole-5-carboxylate 0
                                        vorozole 2
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