Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethotoin
go back to main search page
Accession:CHEBI:4888 term browser browse the term
Definition:An imidazolidine-2,4-dione that is hydantoin substituted by ethyl and phenyl at positions 3 and 5, respectively. An antiepileptic, it is less toxic than phenytoin but also less effective.
Synonyms:exact_synonym: 3-ethyl-5-phenylimidazolidine-2,4-dione
 related_synonym: 1-ethyl-2,5-dioxo-4-phenylimidazolidine;   3-Ethyl-5-phenyl-imidazolidine-2,4-dione;   3-ethyl-5-phenyl-2,4-imidazolidinedione;   3-ethyl-5-phenylhydantoin;   3-ethyl-5-phenylimidazolidin-2,4-dione;   Formula=C11H12N2O2;   InChI=1S/C11H12N2O2/c1-2-13-10(14)9(12-11(13)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H,12,15);   InChIKey=SZQIFWWUIBRPBZ-UHFFFAOYSA-N;   SMILES=CCN1C(=O)NC(C1=O)c1ccccc1;   ethotoine;   ethotoinum;   etotoina
 alt_id: CHEBI:250452
 xref: CAS:86-35-1;   DrugBank:DB00754;   Drug_Central:1088;   HMDB:HMDB0014892;   KEGG:C07839;   KEGG:D00708;   LINCS:LSM-1440
 xref_mesh: MESH:C084606
 xref: PMID:1350205;   PMID:13553007;   PMID:6105055;   PMID:6145119;   Patent:US2793157;   Reaxys:188272;   Wikipedia:Ethotoin


show annotations for term's descendants           Sort by:
ethotoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO ethotoin binds to and results in increased activity of NR1I2 protein CTD PMID:15039302 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        pharmaceutical 19532
          drug 19532
            central nervous system drug 16773
              central nervous system depressant 16289
                anticonvulsant 15330
                  ethotoin 1
                    (R)-ethotoin 0
                    (S)-ethotoin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            organic molecule 19706
                              organic cyclic compound 19495
                                organic heterocyclic compound 18874
                                  organic heteromonocyclic compound 17795
                                    diazolidine 1034
                                      imidazolidines 1024
                                        imidazolidinone 618
                                          imidazolidine-2,4-dione 483
                                            ethotoin 1
                                              (R)-ethotoin 0
                                              (S)-ethotoin 0
paths to the root