disodium selenite - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	disodium selenite	go back to main search page
Accession:	CHEBI:48843	browse the term
Definition:	An inorganic sodium salt composed of sodium and selenite ions in a 2:1 ratio.
Synonyms:	related_synonym:	Formula=Na2O3Se; InChI=1S/2Na.H2O3Se/c;;1-4(2)3/h;;(H2,1,2,3)/q2*+1;/p-2; InChIKey=BVTBRVFYZUCAKH-UHFFFAOYSA-L; Na2SeO3; Natriumselenit; SMILES=[Na+].[Na+].[O-][Se]([O-])=O; disodium selenium trioxide; selenious acid (H2SeO3) disodium salt; selenious acid disodium salt; selenious acid, sodium salt (1:2); sodium selenite
	xref:	AGR:IND607781726; CAS:10102-18-8; DrugBank:DBSALT001761; Gmelin:30272
	xref_mesh:	MESH:D018038
	xref:	PMID:12798669; PMID:16889072; PMID:35486317; PMID:35662217; PMID:36397962; PMID:36567968; PMID:36600950; PMID:36798481; PMID:37006874; PMID:37020163; PMID:37048216; PMID:37302765; PMID:37362095; PMID:37967787; PMID:38008716; PMID:38023380; PMID:38070396; PMID:38150116; PMID:38177716; PMID:38191898; PMID:38374507; PMID:38407796; Wikipedia:Sodium_selenite

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Genes (1508)

disodium selenite

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 1

increases expression

Sodium Selenite results in increased expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 8

decreases expression

Sodium Selenite results in decreased expression of ABCA8 mRNA

NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988

G

ATP binding cassette subfamily B member 11

decreases expression

Sodium Selenite results in decreased expression of ABCB11 mRNA

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP binding cassette subfamily C member 2

multiple interactions

Sodium Selenite inhibits the reaction [arsenite results in increased expression of ABCC2 protein]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]

PMID:34678219 PMID:36464106

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

Sodium Selenite results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

multiple interactions

Sodium Selenite inhibits the reaction [arsenite results in increased expression of ABCC4 protein]

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily D member 1

decreases expression

Sodium Selenite results in decreased expression of ABCD1 mRNA

NCBI chr X:151,428,334...151,450,115
Ensembl chr X:151,428,578...151,450,115

G

ATP binding cassette subfamily F member 1

increases expression

Sodium Selenite results in increased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

ATP binding cassette subfamily G member 2

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ATP binding cassette subfamily G member 5

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

actin binding LIM protein family, member 3

decreases expression

Sodium Selenite results in decreased expression of ABLIM3 mRNA

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

acetyl-CoA acyltransferase 2

increases expression

Sodium Selenite results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

aggrecan

decreases expression

Sodium Selenite results in decreased expression of ACAN mRNA

NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627

G

acetylcholinesterase

increases expression
multiple interactions

Sodium Selenite results in increased expression of ACHE mRNA
[zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased activity of ACHE protein]

PMID:16542727 PMID:36646412

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

acyl-CoA thioesterase 11

decreases expression

Sodium Selenite results in decreased expression of ACOT11 mRNA

NCBI chr 5:121,523,833...121,581,699
Ensembl chr 5:121,527,435...121,581,538

G

actin alpha 2, smooth muscle

multiple interactions

dimethyl mercaptosuccinate inhibits the reaction [Sodium Selenite inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]]; Sodium Selenite inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, beta

increases expression

Sodium Selenite results in increased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

ADAM metallopeptidase domain 11

decreases expression

Sodium Selenite results in decreased expression of ADAM11 mRNA

NCBI chr10:87,724,115...87,742,773
Ensembl chr10:87,724,234...87,741,562

G

ADAM metallopeptidase domain 12

decreases expression

Sodium Selenite results in decreased expression of ADAM12 mRNA

NCBI chr 1:188,686,984...189,014,206
Ensembl chr 1:188,686,989...189,020,667

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

multiple interactions

Sodium Selenite inhibits the reaction [bisphenol A results in decreased expression of ADAMTS5 protein]

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

adenosine deaminase, tRNA-specific 3

increases expression

Sodium Selenite results in increased expression of ADAT3 mRNA

NCBI chr 7:9,109,070...9,113,673
Ensembl chr 7:9,101,187...9,115,340

G

adducin 1

increases expression

Sodium Selenite results in increased expression of ADD1 mRNA

NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182

G

adhesion G protein-coupled receptor L4

increases expression

Sodium Selenite results in increased expression of ADGRL4 mRNA

NCBI chr 2:240,354,909...240,457,231
Ensembl chr 2:240,354,941...240,457,225

G

adhesion G protein-coupled receptor V1

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of ADGRV1 mRNA

NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688

G

adiponectin, C1Q and collagen domain containing

decreases expression

Sodium Selenite results in decreased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adenylosuccinate lyase

increases expression

Sodium Selenite results in increased expression of ADSL mRNA

NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760

G

AE binding protein 1

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of AEBP1 mRNA

NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877

G

AFG1 like ATPase

increases expression

Sodium Selenite results in increased expression of AFG1L mRNA

NCBI chr20:45,798,344...45,967,997
Ensembl chr20:45,798,349...45,967,906

G

aspartylglucosaminidase

increases expression

Sodium Selenite results in increased expression of AGA mRNA

NCBI chr16:38,504,661...38,516,607
Ensembl chr16:38,504,663...38,516,606

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

increases expression

Sodium Selenite results in increased expression of AGAP2 mRNA

NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295

G

advanced glycosylation end product-specific receptor

multiple interactions

Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]

NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078

G

alkylglycerol monooxygenase

decreases expression

Sodium Selenite results in decreased expression of AGMO mRNA

NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623

G

anterior gradient 2, protein disulphide isomerase family member

decreases expression

Sodium Selenite results in decreased expression of AGR2 mRNA

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

aryl-hydrocarbon receptor repressor

increases expression
multiple interactions

Sodium Selenite results in increased expression of AHRR mRNA
[ptaquiloside co-treated with Sodium Selenite] results in increased expression of AHRR mRNA

NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673

G

axin interactor, dorsalization associated

increases expression

Sodium Selenite results in increased expression of AIDA mRNA

NCBI chr13:94,940,311...94,967,920
Ensembl chr13:94,939,741...94,967,920

G

allograft inflammatory factor 1-like

decreases expression

Sodium Selenite results in decreased expression of AIF1L mRNA

NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023

G

apoptosis inducing factor, mitochondria associated 1

increases expression

Sodium Selenite results in increased expression of AIFM1 mRNA

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

Sodium Selenite results in increased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

aryl-hydrocarbon receptor-interacting protein

increases expression

Sodium Selenite results in increased expression of AIP mRNA

NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122

G

akirin 1

increases expression

Sodium Selenite results in increased expression of AKIRIN1 mRNA

NCBI chr 5:135,989,378...136,004,782
Ensembl chr 5:135,989,465...136,004,762

G

AKT serine/threonine kinase 1

decreases expression
increases phosphorylation
multiple interactions

Sodium Selenite results in decreased expression of AKT1 mRNA
Sodium Selenite results in increased phosphorylation of AKT1 protein
mitoquinone inhibits the reaction [Sodium Selenite inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; Sodium Selenite inhibits the reaction [2-cresol results in increased expression of AKT1 mRNA]; Sodium Selenite inhibits the reaction [citreoviridin results in decreased phosphorylation of AKT1 protein]; Sodium Selenite inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]

PMID:12896980 PMID:15845651 PMID:16705456 PMID:21705299 PMID:24140496 More...

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

decreases activity
multiple interactions

Sodium Selenite results in decreased activity of ALAD protein
Mercuric Chloride promotes the reaction [Sodium Selenite results in decreased activity of ALAD protein]; Sodium Selenite inhibits the reaction [Mercury results in decreased activity of ALAD protein]; Sodium Selenite promotes the reaction [Mercuric Chloride results in decreased activity of ALAD protein]

PMID:12499120 PMID:12595158

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

albumin

multiple interactions

[Sodium Selenite co-treated with Plant Extracts] inhibits the reaction [sodium arsenite results in decreased expression of ALB protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of ALB protein]

PMID:24954678 PMID:26085057

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

alkB homolog 6

increases expression

Sodium Selenite results in increased expression of ALKBH6 mRNA

NCBI chr 1:85,563,511...85,568,977
Ensembl chr 1:85,563,592...85,568,973

G

arachidonate 15-lipoxygenase

multiple interactions

Sodium Selenite inhibits the reaction [Selenium deficiency results in increased expression of ALOX15 protein]

NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874

G

anaphase promoting complex subunit 11

increases expression

Sodium Selenite results in increased expression of ANAPC11 mRNA

NCBI chr10:105,875,209...105,886,307

G

angiogenin

increases expression

Sodium Selenite results in increased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

angel homolog 1

decreases expression

Sodium Selenite results in decreased expression of ANGEL1 mRNA

NCBI chr 6:106,349,125...106,386,202
Ensembl chr 6:106,349,126...106,386,209

G

angiopoietin-like 2

decreases expression

Sodium Selenite results in decreased expression of ANGPTL2 mRNA

NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178

G

ankyrin repeat family A member 2

increases expression

Sodium Selenite results in increased expression of ANKRA2 mRNA

NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730

G

ankyrin repeat domain containing 26

decreases expression

Sodium Selenite results in decreased expression of ANKRD26 mRNA

NCBI chr 4:151,670,604...151,740,032
Ensembl chr 4:151,672,037...151,739,968

G

ankyrin repeat domain 46

increases expression

Sodium Selenite results in increased expression of ANKRD46 mRNA

NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132

G

anillin, actin binding protein

decreases expression

Sodium Selenite results in decreased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

annexin A1

increases expression

Sodium Selenite results in increased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A11

increases expression

Sodium Selenite results in increased expression of ANXA11 mRNA

NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797

G

annexin A7

increases expression

Sodium Selenite results in increased expression of ANXA7 mRNA

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

G

APC regulator of WNT signaling pathway

decreases methylation
increases expression

Sodium Selenite results in decreased methylation of APC promoter
Sodium Selenite results in increased expression of APC mRNA

NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696

G

APC down-regulated 1

decreases expression

Sodium Selenite results in decreased expression of APCDD1 mRNA

NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070

G

apurinic/apyrimidinic endodeoxyribonuclease 1

increases expression
multiple interactions

Sodium Selenite results in increased expression of APEX1 mRNA
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of and affects the localization of APEX1 protein; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of APEX1 mRNA

PMID:18175754 PMID:28757135

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

adipocyte plasma membrane associated protein

increases expression

Sodium Selenite results in increased expression of APMAP mRNA

NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341

G

apolipoprotein A1

decreases expression

Sodium Selenite results in decreased expression of APOA1 mRNA

NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035

G

amyloid beta precursor protein

decreases expression

Sodium Selenite results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

adenine phosphoribosyl transferase

increases expression

Sodium Selenite results in increased expression of APRT mRNA

NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431

G

aquaporin 7

increases expression
multiple interactions

Sodium Selenite results in increased expression of AQP7 mRNA
Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of AQP7 mRNA]

NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642

G

androgen receptor

multiple interactions
decreases expression

[Sodium Selenite results in decreased activity of SP1 protein] which results in decreased expression of AR protein; [Sodium Selenite results in increased expression of JUN protein] which results in decreased activity of AR protein; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR mRNA]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR protein]; Sodium Selenite inhibits the reaction [IL6 protein results in increased activity of AR protein]
Sodium Selenite results in decreased expression of AR mRNA; Sodium Selenite results in decreased expression of AR protein

PMID:16928829 PMID:17346688 PMID:18760546

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

ADP-ribosylation factor 5

increases expression

Sodium Selenite results in increased expression of ARF5 mRNA

NCBI chr 4:57,038,521...57,041,447
Ensembl chr 4:57,038,521...57,041,441

G

ADP-ribosylation factor GTPase activating protein 3

increases expression

Sodium Selenite results in increased expression of ARFGAP3 mRNA

NCBI chr 7:114,432,873...114,479,206
Ensembl chr 7:114,432,873...114,479,208

G

arginase 1

increases activity
multiple interactions
increases expression

Sodium Selenite results in increased activity of ARG1 protein
4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [Sodium Selenite results in increased activity of ARG1 protein]
Sodium Selenite results in increased expression of ARG1 mRNA

PMID:21669866 PMID:25187657

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

Rho GTPase activating protein 6

decreases expression

Sodium Selenite results in decreased expression of ARHGAP6 mRNA

NCBI chr X:24,953,464...25,490,003
Ensembl chr X:24,953,464...25,488,663

G

Rho guanine nucleotide exchange factor 1

decreases expression

Sodium Selenite results in decreased expression of ARHGEF1 mRNA

NCBI chr 1:80,499,026...80,520,954
Ensembl chr 1:80,499,131...80,520,953

G

Rac/Cdc42 guanine nucleotide exchange factor 6

increases expression

Sodium Selenite results in increased expression of ARHGEF6 mRNA

NCBI chr X:135,145,447...135,264,636
Ensembl chr X:135,146,786...135,275,304

G

AT-rich interaction domain 5A

increases expression

Sodium Selenite results in increased expression of ARID5A mRNA

NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597

G

ariadne RBR E3 ubiquitin protein ligase 2

increases expression

Sodium Selenite results in increased expression of ARIH2 mRNA

NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852

G

arkadia (RNF111) N-terminal like PKA signaling regulator 2N

decreases expression

Sodium Selenite results in decreased expression of ARK2N mRNA

NCBI chr18:71,155,956...71,243,655
Ensembl chr18:71,157,700...71,243,482

G

ADP-ribosylation factor like GTPase 2 binding protein

increases expression

Sodium Selenite results in increased expression of ARL2BP mRNA

NCBI chr19:10,336,921...10,346,555
Ensembl chr19:10,336,921...10,346,564

G

ADP ribosylation factor like GTPase 4C

increases expression

Sodium Selenite results in increased expression of ARL4C mRNA

NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513

G

ADP-ribosylation factor like GTPase 6 interacting protein 4

increases expression

Sodium Selenite results in increased expression of ARL6IP4 mRNA

NCBI chr12:32,479,623...32,481,768
Ensembl chr12:32,479,625...32,481,799

G

armadillo repeat containing, X-linked 5

increases expression

Sodium Selenite results in increased expression of ARMCX5 mRNA

NCBI chr X:98,709,921...98,714,347
Ensembl chr X:98,709,841...98,714,674

G

aryl hydrocarbon receptor nuclear translocator 2

decreases expression

Sodium Selenite results in decreased expression of ARNT2 mRNA

NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153

G

actin related protein 2/3 complex, subunit 2

increases expression

Sodium Selenite results in increased expression of ARPC2 mRNA

NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471

G

ADP-ribosyltransferase 4

decreases expression

Sodium Selenite results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

N-acylsphingosine amidohydrolase 2

increases expression

Sodium Selenite results in increased expression of ASAH2 mRNA

NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162

G

activating signal cointegrator 1 complex subunit 3

decreases expression

Sodium Selenite results in decreased expression of ASCC3 mRNA

NCBI chr20:53,510,137...53,795,446
Ensembl chr20:53,510,184...53,790,165

G

achaete-scute family bHLH transcription factor 1

decreases expression

Sodium Selenite results in decreased expression of ASCL1 mRNA

NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993

G

acid sensing ion channel subunit 2

decreases expression

Sodium Selenite results in decreased expression of ASIC2 mRNA

NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

Sodium Selenite results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

assembly factor for spindle microtubules

decreases expression

Sodium Selenite results in decreased expression of ASPM mRNA

NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755

G

ATPase family, AAA domain containing 2B

decreases expression

Sodium Selenite results in decreased expression of ATAD2B mRNA

NCBI chr 6:27,914,546...28,070,103
Ensembl chr 6:27,912,862...28,067,047

G

activating transcription factor 4

increases expression

Sodium Selenite results in increased expression of ATF4 protein

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 5

increases expression

Sodium Selenite results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

activating transcription factor 6

increases expression
multiple interactions

Sodium Selenite results in increased expression of ATF6 protein
4-phenylbutyric acid inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 4A, cysteine peptidase

increases expression

Sodium Selenite results in increased expression of ATG4A mRNA

NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268

G

autophagy related 4C, cysteine peptidase

increases expression

Sodium Selenite results in increased expression of ATG4C mRNA

NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830

G

autophagy related 5

increases expression

Sodium Selenite results in increased expression of ATG5 protein

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

ATM serine/threonine kinase

increases phosphorylation

Sodium Selenite results in increased phosphorylation of ATM protein

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase Na+/K+ transporting subunit alpha 4

increases expression

Sodium Selenite results in increased expression of ATP1A4 mRNA

NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687

G

ATPase plasma membrane Ca2+ transporting 3

decreases expression

Sodium Selenite results in decreased expression of ATP2B3 mRNA

NCBI chr X:151,216,483...151,289,069
Ensembl chr X:151,216,507...151,286,775

G

ATP synthase F1 subunit epsilon

increases expression

Sodium Selenite results in increased expression of ATP5F1E mRNA

NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450

G

ATP synthase membrane subunit c locus 2

increases expression

Sodium Selenite results in increased expression of ATP5MC2 mRNA

NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733

G

ATP synthase peripheral stalk-membrane subunit b

increases expression

Sodium Selenite results in increased expression of ATP5PB mRNA

NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418

G

ATP synthase peripheral stalk subunit d

increases expression

Sodium Selenite results in increased expression of ATP5PD mRNA

NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479

G

ATPase H+ transporting V0 subunit a1

decreases expression

Sodium Selenite results in decreased expression of ATP6V0A1 mRNA

NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895

G

ATPase, H+ transporting V0 subunit e2

increases expression

Sodium Selenite results in increased expression of ATP6V0E2 mRNA

NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777

G

ATPase H+ transporting V1 subunit G2

increases expression

Sodium Selenite results in increased expression of ATP6V1G2 mRNA

NCBI chr20:3,587,681...3,591,309
Ensembl chr20:3,587,686...3,590,481

G

ATPase phospholipid transporting 8B1

decreases expression

Sodium Selenite results in decreased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

AUP1, lipid droplet regulating VLDL assembly factor

increases expression

Sodium Selenite results in increased expression of AUP1 mRNA

NCBI chr 4:115,560,274...115,563,346
Ensembl chr 4:115,560,261...115,563,346

G

axin 1

increases expression

Sodium Selenite results in increased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

Beta-1,3-galactosyltransferase 6

increases expression

Sodium Selenite results in increased expression of B3GALT6 mRNA

NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6

increases expression

Sodium Selenite results in increased expression of B3GNT6 mRNA

NCBI chr 1:152,484,572...152,496,226
Ensembl chr 1:152,486,343...152,492,150

G

beta-1,4-glucuronyltransferase 1

increases expression

Sodium Selenite results in increased expression of B4GAT1 mRNA

NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065

G

BAG cochaperone 5

decreases expression

Sodium Selenite results in decreased expression of BAG5 mRNA

NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970

G

BCL2-antagonist/killer 1

increases expression

Sodium Selenite results in increased expression of BAK1 mRNA

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

Btg3 associated nuclear protein

increases expression

Sodium Selenite results in increased expression of BANP mRNA

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

basic leucine zipper ATF-like transcription factor 3

decreases expression

Sodium Selenite results in decreased expression of BATF3 mRNA

NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139

G

BCL2 associated X, apoptosis regulator

increases expression
decreases expression
multiple interactions

Sodium Selenite results in increased expression of BAX mRNA; Sodium Selenite results in increased expression of BAX protein
Sodium Selenite results in decreased expression of BAX protein
Sodium Selenite inhibits the reaction [2-cresol results in increased expression of BAX mRNA]; Sodium Selenite inhibits the reaction [citreoviridin results in increased expression of BAX protein]
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of BAX protein

PMID:16542727 PMID:16705456 PMID:18209489 PMID:21705299 PMID:28757135 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

bromodomain adjacent to zinc finger domain, 1A

increases expression

Sodium Selenite results in increased expression of BAZ1A mRNA

NCBI chr 6:72,389,701...72,512,516
Ensembl chr 6:72,389,703...72,512,459

G

Bcl-2 binding component 3

increases expression

Sodium Selenite results in increased expression of BBC3 mRNA

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

Bardet-Biedl syndrome 4

decreases expression

Sodium Selenite results in decreased expression of BBS4 mRNA

NCBI chr 8:59,731,912...59,765,408
Ensembl chr 8:59,731,912...59,765,607

G

BCL2, apoptosis regulator

multiple interactions
increases expression
decreases expression

Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of BCL2 protein]; Sodium Selenite promotes the reaction [Buthionine Sulfoximine results in decreased expression of BCL2 mRNA]
Sodium Selenite results in increased expression of BCL2 protein
Sodium Selenite inhibits the reaction [2-cresol results in increased expression of BCL2 mRNA]; Sodium Selenite inhibits the reaction [cholestane-3,5,6-triol results in increased expression of BCL2 mRNA]; Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of BCL2 protein]
Sodium Selenite results in decreased expression of BCL2 mRNA
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of BCL2 protein
Sodium Selenite results in decreased expression of BCL2 protein

PMID:16039982 PMID:16542727 PMID:17989939 PMID:18209489 PMID:19363675 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL9, transcription coactivator

decreases expression

Sodium Selenite results in decreased expression of BCL9 mRNA

NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435

G

beclin 1

increases expression

Sodium Selenite results in increased expression of BECN1 protein

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

BRD4 interacting chromatin remodeling complex associated protein

increases expression

Sodium Selenite results in increased expression of BICRA mRNA

NCBI chr 1:76,661,897...76,736,146
Ensembl chr 1:76,661,897...76,737,157

G

BCL2-interacting killer

decreases expression

Sodium Selenite results in decreased expression of BIK mRNA

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

baculoviral IAP repeat-containing 2

decreases expression
increases expression
decreases abundance

Sodium Selenite results in decreased expression of BIRC2 protein
Sodium Selenite results in increased expression of BIRC2 mRNA
Selenite decreases abundance of BIRC2 protein in colorectal cancer cells

CTD
RGD

PMID:14737004 PMID:16705456 PMID:24577083

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

decreases expression
decreases abundance

Sodium Selenite results in decreased expression of BIRC3 mRNA
Selenite decreases abundance of BIRC3 protein in colorectal cancer cells

CTD
RGD

PMID:16705456 PMID:24577083

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

basic leucine zipper nuclear factor 1

increases expression

Sodium Selenite results in increased expression of BLZF1 mRNA

NCBI chr13:76,641,757...76,656,977
Ensembl chr13:76,641,515...76,656,999

G

bone morphogenetic protein 4

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of BMP4 mRNA
Sodium Selenite results in decreased expression of BMP4 mRNA

PMID:23274088 PMID:24383545

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

BCL2 interacting protein like

decreases expression

Sodium Selenite results in decreased expression of BNIPL mRNA

NCBI chr 2:182,818,593...182,830,421
Ensembl chr 2:182,818,595...182,828,588

G

BLOC-1 related complex subunit 7

increases expression

Sodium Selenite results in increased expression of BORCS7 mRNA

NCBI chr 1:245,564,347...245,578,182
Ensembl chr 1:245,564,369...245,579,343

G

B-Raf proto-oncogene, serine/threonine kinase

increases expression

Sodium Selenite results in increased expression of BRAF mRNA

NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463

G

BRCA1-associated ATM activator 1

increases expression

Sodium Selenite results in increased expression of BRAT1 mRNA

NCBI chr12:13,928,889...13,951,760
Ensembl chr12:13,928,898...13,941,248

G

BRCA1, DNA repair associated

decreases expression

Sodium Selenite results in decreased expression of BRCA1 mRNA

NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304

G

BRCA2, DNA repair associated

decreases expression

Sodium Selenite results in decreased expression of BRCA2 mRNA

NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567

G

BRF1, RNA polymerase III transcription initiation factor subunit

decreases expression

Sodium Selenite results in decreased expression of BRF1 mRNA

NCBI chr 6:132,034,378...132,081,313
Ensembl chr 6:132,037,272...132,081,278

G

BTB domain containing 7

decreases expression

Sodium Selenite results in decreased expression of BTBD7 mRNA

NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405

G

BTG anti-proliferation factor 2

increases expression

Sodium Selenite results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

B and T lymphocyte associated

decreases expression

Sodium Selenite results in decreased expression of BTLA mRNA

NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181

G

similar to human chromosome 18 open reading frame 21

increases expression

Sodium Selenite results in increased expression of C18ORF21 mRNA

NCBI chr18:15,779,349...15,786,772
Ensembl chr18:15,779,368...15,787,894

G

similar to human chromosome 5 open reading frame 46

decreases expression

Sodium Selenite results in decreased expression of C5ORF46 mRNA

NCBI chr18:35,948,402...35,969,502
Ensembl chr18:35,948,402...35,969,502

G

similar to human chromosome 1 open reading frame 131

increases expression

Sodium Selenite results in increased expression of FSAF1 mRNA

NCBI chr19:52,807,932...52,822,259
Ensembl chr19:52,807,934...52,822,267

G

similar to human chromosome 9 open reading frame 40

increases expression

Sodium Selenite results in increased expression of C9ORF40 mRNA

NCBI chr 1:216,128,687...216,132,896
Ensembl chr 1:216,128,651...216,133,045

G

complement C1q C chain

decreases expression

Sodium Selenite results in decreased expression of C1QC mRNA

NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017

G

similar to human chromosome 1 open reading frame 162

increases expression

Sodium Selenite results in increased expression of C1ORF162 mRNA

NCBI chr 2:193,410,730...193,420,824
Ensembl chr 2:193,412,971...193,420,030

G

complement C8 alpha chain

decreases expression

Sodium Selenite results in decreased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

complement C9

decreases expression

Sodium Selenite results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

similar to human chromosome 2 open reading frame 88

decreases expression

Sodium Selenite results in decreased expression of C2ORF88 mRNA

NCBI chr 9:48,539,140...48,584,882
Ensembl chr 9:48,568,409...48,584,831

G

calcium voltage-gated channel subunit alpha1 C

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of CACNA1C mRNA

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

G

calcium voltage-gated channel auxiliary subunit alpha2delta 3

increases expression

Sodium Selenite results in increased expression of CACNA2D3 mRNA

NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351

G

calcium voltage-gated channel auxiliary subunit alpha2delta 4

decreases expression

Sodium Selenite results in decreased expression of CACNA2D4 mRNA

NCBI chr 4:152,408,588...152,521,478
Ensembl chr 4:152,408,657...152,521,268

G

calcium voltage-gated channel auxiliary subunit beta 1

increases expression

Sodium Selenite results in increased expression of CACNB1 mRNA

NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694

G

calcium voltage-gated channel auxiliary subunit beta 4

decreases expression

Sodium Selenite results in decreased expression of CACNB4 mRNA

NCBI chr 3:36,906,771...37,169,165
Ensembl chr 3:36,910,427...37,168,944

G

calcitonin-related polypeptide alpha

decreases response to substance

CALCA protein results in decreased susceptibility to Sodium Selenite

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

calmodulin 1

increases expression

Sodium Selenite results in increased expression of CALM1 mRNA

NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227

G

calcium modulating ligand

increases expression

Sodium Selenite results in increased expression of CAMLG mRNA

NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552

G

cathelicidin antimicrobial peptide

increases expression

Sodium Selenite results in increased expression of CAMP mRNA

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

G

calpain, small subunit 2

increases expression

Sodium Selenite results in increased expression of CAPNS2 mRNA

NCBI chr19:14,104,334...14,105,276

G

cell cycle associated protein 1

increases expression

Sodium Selenite results in increased expression of CAPRIN1 mRNA

NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502

G

calcium responsive transcription factor

decreases expression

Sodium Selenite results in decreased expression of CARF mRNA

NCBI chr 9:61,502,368...61,552,433
Ensembl chr 9:61,506,956...61,550,462

G

calcium/calmodulin dependent serine protein kinase

decreases expression

Sodium Selenite results in decreased expression of CASK mRNA

NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694

G

caspase 12

decreases expression

Sodium Selenite results in decreased expression of CASP12 protein

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

decreases expression
multiple interactions
decreases activity
increases expression
increases activity
increases cleavage

Sodium Selenite results in decreased expression of CASP3 mRNA
Sodium Selenite promotes the reaction [Buthionine Sulfoximine results in increased expression of CASP3 mRNA]
Sodium Selenite results in decreased activity of CASP3 protein
Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of CASP3 mRNA]
Sodium Selenite results in increased activity of CASP3 protein
Sodium Selenite results in increased cleavage of CASP3 protein
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased cleavage of CASP3 protein

PMID:16705456 PMID:17989939 PMID:18209489 PMID:19363675 PMID:20067779 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

increases cleavage

Sodium Selenite results in increased cleavage of CASP4 protein

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 7

affects expression
multiple interactions
increases cleavage

Sodium Selenite affects the expression of CASP7 mRNA
Sodium Selenite inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]
Sodium Selenite results in increased cleavage of CASP7 protein

PMID:16705456 PMID:28161410

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

increases expression
decreases activity
increases cleavage

Sodium Selenite results in increased expression of CASP8 mRNA
Sodium Selenite results in decreased activity of CASP8 protein
Sodium Selenite results in increased cleavage of CASP8 protein

PMID:18209489 PMID:19363675 PMID:34520753

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

increases expression
decreases activity
increases cleavage

Sodium Selenite results in increased expression of CASP9 mRNA
Sodium Selenite results in decreased activity of CASP9 protein
Sodium Selenite results in increased cleavage of CASP9 protein

PMID:16705456 PMID:18209489 PMID:28161410

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

decreases expression
multiple interactions
increases activity
decreases activity

Sodium Selenite results in decreased expression of CAT mRNA
[[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Sodium Selenite co-treated with alpha-Tocopherol] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; [Vitamin E co-treated with Sodium Selenite] inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; [zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]; Acetylcarnitine inhibits the reaction [Sodium Selenite results in decreased expression of CAT mRNA]; Curcumin inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; isorhamnetin 3-O-glucoside inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; lupeol inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; pimagedine inhibits the reaction [Sodium Selenite results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of CAT protein]; Sodium Selenite inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [sodium arsenite results in decreased expression of CAT mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Sodium Selenite results in increased activity of CAT protein

PMID:19481068 PMID:20067779 PMID:20566334 PMID:20643113 PMID:22476978 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 2

decreases expression

Sodium Selenite results in decreased expression of CAV2 mRNA

NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244

G

cystathionine beta synthase

increases expression

Sodium Selenite results in increased expression of CBS mRNA

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

collagen and calcium binding EGF domains 1

decreases expression

Sodium Selenite results in decreased expression of CCBE1 mRNA

NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400

G

coiled-coil domain containing 142

increases expression

Sodium Selenite results in increased expression of CCDC142 mRNA

NCBI chr 4:115,606,151...115,616,223
Ensembl chr 4:115,608,485...115,616,216

G

coiled-coil domain containing 167

increases expression

Sodium Selenite results in increased expression of CCDC167 mRNA

NCBI chr20:7,763,927...7,782,090
Ensembl chr20:7,751,782...7,781,613

G

coiled-coil domain containing 6

increases expression

Sodium Selenite results in increased expression of CCDC6 mRNA

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

G

coiled-coil domain containing 69

decreases expression

Sodium Selenite results in decreased expression of CCDC69 mRNA

NCBI chr10:39,173,282...39,200,358
Ensembl chr10:39,173,282...39,199,878

G

coiled-coil domain containing 86

increases expression

Sodium Selenite results in increased expression of CCDC86 mRNA

NCBI chr 1:207,590,167...207,596,547
Ensembl chr 1:207,590,168...207,596,544

G

C-C motif chemokine ligand 21

increases expression

Sodium Selenite results in increased expression of CCL21 mRNA

NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686

G

C-C motif chemokine ligand 24

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of CCL24 mRNA
Sodium Selenite results in decreased expression of CCL24 mRNA

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

G

cyclin A2

decreases expression

Sodium Selenite results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression
multiple interactions

Sodium Selenite results in decreased expression of CCNB1 mRNA
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 mRNA; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of CCNB1 protein

PMID:24383545 PMID:28757135

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin C

decreases expression

Sodium Selenite results in decreased expression of CCNC mRNA

NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584

G

cyclin D1

increases expression
decreases expression

Sodium Selenite results in increased expression of CCND1 mRNA
Sodium Selenite results in decreased expression of CCND1 mRNA; Sodium Selenite results in decreased expression of CCND1 protein

PMID:16705456 PMID:19276161

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

decreases expression

Sodium Selenite results in decreased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin E1

increases expression

Sodium Selenite results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin G1

decreases expression

Sodium Selenite results in decreased expression of CCNG1 mRNA

NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641

G

centriole, cilia and spindle-associated protein

decreases expression

Sodium Selenite results in decreased expression of CCSAP mRNA

NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753

G

chaperonin containing TCP1 subunit 3

increases expression

Sodium Selenite results in increased expression of CCT3 mRNA

NCBI chr 2:173,765,701...173,790,353
Ensembl chr 2:173,765,698...173,790,757

G

chaperonin containing TCP1 subunit 6A

increases expression

Sodium Selenite results in increased expression of CCT6A mRNA

NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337

G

CD14 molecule

increases expression
decreases expression

Sodium Selenite results in increased expression of CD14 mRNA
Sodium Selenite results in decreased expression of CD14 mRNA

PMID:18175754 PMID:23274088

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD180 molecule

decreases expression

Sodium Selenite results in decreased expression of CD180 mRNA

NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936

G

Cd2 molecule

increases expression

Sodium Selenite results in increased expression of CD2 mRNA

NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026

G

CD226 molecule

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of CD226 mRNA

NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051

G

CD300 molecule-like family member b

decreases expression

Sodium Selenite results in decreased expression of TREM5 mRNA

NCBI chr10:99,964,801...99,974,790
Ensembl chr10:99,964,801...99,974,790

G

Cd47 molecule

increases expression

Sodium Selenite results in increased expression of CD47 mRNA

NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425

G

Cd5 molecule

decreases expression

Sodium Selenite results in decreased expression of CD5 mRNA

NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313

G

CD52 molecule

increases expression

Sodium Selenite results in increased expression of CD52 mRNA

NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348

G

Cd53 molecule

increases expression

Sodium Selenite results in increased expression of CD53 mRNA

NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657

G

Cd70 molecule

increases expression

Sodium Selenite results in increased expression of CD70 mRNA

PMID:16705456 PMID:18175754

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

G

CD79b molecule

decreases expression

Sodium Selenite results in decreased expression of CD79B mRNA

NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625

G

CD83 molecule

increases expression

Sodium Selenite results in increased expression of CD83 mRNA

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

G

CD84 molecule

decreases expression

Sodium Selenite results in decreased expression of CD84 mRNA

NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076

G

CD8 subunit beta

increases expression

Sodium Selenite results in increased expression of CD8B1 mRNA

NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553

G

CD96 molecule

increases expression

Sodium Selenite results in increased expression of CD96 mRNA

NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621

G

cell division cycle 14B

decreases expression

Sodium Selenite results in decreased expression of CDC14B mRNA

NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235

G

cell division cycle 37, HSP90 cochaperone

increases expression

Sodium Selenite results in increased expression of CDC37 mRNA

NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809

G

cell division cycle 42

increases expression

Sodium Selenite results in increased expression of CDC42 mRNA

NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111

G

cell division cycle 6

decreases expression

Sodium Selenite results in decreased expression of CDC6 mRNA

NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011

G

cadherin 2

decreases expression

Sodium Selenite results in decreased expression of CDH2 mRNA

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cyclin-dependent kinase 17

decreases expression
increases expression

Sodium Selenite results in decreased expression of CDK17 mRNA
Sodium Selenite results in increased expression of CDK17 mRNA

PMID:16705456 PMID:18175754

NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910

G

cyclin-dependent kinase 4

increases expression

Sodium Selenite results in increased expression of CDK4 mRNA

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 5

decreases expression

Sodium Selenite results in decreased expression of CDK5 mRNA

NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112

G

cyclin-dependent kinase 5 regulatory subunit 1

increases expression

Sodium Selenite results in increased expression of CDK5R1 mRNA

NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456

G

cyclin-dependent kinase 7

decreases expression

Sodium Selenite results in decreased expression of CDK7 mRNA

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cyclin-dependent kinase 9

decreases expression

Sodium Selenite results in decreased expression of CDK9 mRNA

NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
increases expression

[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of CDKN1A mRNA; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of CDKN1A protein; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased activity of CDKN1A protein]
Sodium Selenite results in increased expression of CDKN1A mRNA; Sodium Selenite results in increased expression of CDKN1A protein

PMID:21515331 PMID:24383545 PMID:25204997 PMID:28757135

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression

Sodium Selenite results in increased expression of CDKN1B protein

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 1C

increases expression

Sodium Selenite results in increased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

increases expression

Sodium Selenite results in increased expression of CDKN2A protein

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

cyclin-dependent kinase inhibitor 2B

increases expression

Sodium Selenite results in increased expression of CDKN2B mRNA

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cyclin-dependent kinase inhibitor 3

decreases expression

Sodium Selenite results in decreased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CCAAT/enhancer binding protein epsilon

increases expression

Sodium Selenite results in increased expression of CEBPE mRNA

NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814

G

CCAAT/enhancer binding protein gamma

increases expression

Sodium Selenite results in increased expression of CEBPG mRNA

NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569

G

chymotrypsin like elastase 1

decreases expression

Sodium Selenite results in decreased expression of CELA1 mRNA

NCBI chr 7:131,773,161...131,786,300
Ensembl chr 7:131,742,002...131,786,285

G

CUGBP, Elav-like family member 6

increases expression

Sodium Selenite results in increased expression of CELF6 mRNA

NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041

G

centromere protein E

decreases expression

Sodium Selenite results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein F

decreases expression

Sodium Selenite results in decreased expression of CENPF mRNA

NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669

G

centromere protein K

decreases expression

Sodium Selenite results in decreased expression of CENPK mRNA

NCBI chr 2:35,360,390...35,421,372
Ensembl chr 2:35,360,132...35,385,706

G

centrosomal protein 76

decreases expression

Sodium Selenite results in decreased expression of CEP76 mRNA

NCBI chr18:61,174,514...61,208,512
Ensembl chr18:61,178,310...61,208,504

G

centrosomal protein 85

decreases expression

Sodium Selenite results in decreased expression of CEP85 mRNA

NCBI chr 5:146,356,571...146,404,155
Ensembl chr 5:146,356,576...146,404,060

G

centrin 2

decreases expression

Sodium Selenite results in decreased expression of CETN2 mRNA

NCBI chr X:150,769,944...150,774,833
Ensembl chr X:150,769,953...150,774,919

G

cofilin 1

increases expression

Sodium Selenite results in increased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

Sodium Selenite results in increased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

chromatin assembly factor 1 subunit B

decreases expression

Sodium Selenite results in decreased expression of CHAF1B mRNA

NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070

G

chromosome alignment maintaining phosphoprotein 1

increases expression

Sodium Selenite results in increased expression of CHAMP1 mRNA

NCBI chr16:75,733,958...75,744,931
Ensembl chr16:75,733,805...75,744,984

G

coiled-coil-helix-coiled-coil-helix domain containing 2

increases expression

Sodium Selenite results in increased expression of CHCHD2 mRNA

NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755

G

chromogranin A

increases expression

Sodium Selenite results in increased expression of CHGA mRNA

NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398

G

CHM like Rab escort protein

decreases expression

Sodium Selenite results in decreased expression of CHML mRNA

NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862

G

charged multivesicular body protein 2A

increases expression

Sodium Selenite results in increased expression of CHMP2A mRNA

NCBI chr 1:73,660,045...73,662,894
Ensembl chr 1:73,660,046...73,662,452

G

charged multivesicular body protein 6

decreases expression

Sodium Selenite results in decreased expression of CHMP6 mRNA

NCBI chr10:105,191,972...105,197,642
Ensembl chr10:105,191,950...105,197,640

G

chromatin accessibility complex subunit 1

increases expression

Sodium Selenite results in increased expression of CHRAC1 mRNA

NCBI chr 7:105,013,047...105,016,435
Ensembl chr 7:105,013,015...105,017,136

G

chondroitin sulfate synthase 1

increases expression

Sodium Selenite results in increased expression of CHSY1 mRNA

NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601

G

component of inhibitor of nuclear factor kappa B kinase complex

affects localization

Sodium Selenite affects the localization of CHUK protein

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

churchill domain containing 1

increases expression

Sodium Selenite results in increased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

calcium and integrin binding family member 3

decreases expression

Sodium Selenite results in decreased expression of CIB3 mRNA

NCBI chr16:17,622,431...17,631,827
Ensembl chr16:17,622,501...17,631,841

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

increases expression

Sodium Selenite results in increased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

creatine kinase B

multiple interactions

Sodium Selenite inhibits the reaction [citreoviridin results in increased secretion of [CKM protein binds to CKB protein]]

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

creatine kinase, M-type

multiple interactions

Sodium Selenite inhibits the reaction [citreoviridin results in increased secretion of [CKM protein binds to CKB protein]]

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

CDC28 protein kinase regulatory subunit 1B

increases expression

Sodium Selenite results in increased expression of CKS1B mRNA

NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636

G

CDC28 protein kinase regulatory subunit 2

increases expression

Sodium Selenite results in increased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

chloride channel CLIC-like 1

decreases expression

Sodium Selenite results in decreased expression of CLCC1 mRNA

NCBI chr 2:196,296,350...196,326,914
Ensembl chr 2:196,296,393...196,326,913

G

chloride voltage-gated channel 1

decreases expression

Sodium Selenite results in decreased expression of CLCN1 mRNA

NCBI chr 4:71,171,949...71,201,483
Ensembl chr 4:71,172,547...71,199,984

G

chloride voltage-gated channel 6

decreases expression

Sodium Selenite results in decreased expression of CLCN6 mRNA

NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059

G

claudin 18

decreases expression

Sodium Selenite results in decreased expression of CLDN18 mRNA

NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351

G

C-type lectin domain family 1, member B

decreases expression

Sodium Selenite results in decreased expression of CLEC1B mRNA

NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291

G

calmegin

increases expression

Sodium Selenite results in increased expression of CLGN mRNA

NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758

G

chloride intracellular channel 5

increases expression

Sodium Selenite results in increased expression of CLIC5 mRNA

NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427

G

CDC-like kinase 3

affects expression

Sodium Selenite affects the expression of CLK3 mRNA

NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181

G

chloride nucleotide-sensitive channel 1A

increases expression

Sodium Selenite results in increased expression of CLNS1A mRNA

NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661

G

caseinolytic mitochondrial matrix peptidase proteolytic subunit

increases expression

Sodium Selenite results in increased expression of CLPP mRNA

NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693

G

CLPTM1 regulator of GABA type A receptor forward trafficking

decreases expression

Sodium Selenite results in decreased expression of CLPTM1 mRNA

NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092

G

clathrin, light chain A

increases expression

Sodium Selenite results in increased expression of CLTA mRNA

NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472

G

carnosine dipeptidase 1

decreases expression

Sodium Selenite results in decreased expression of CNDP1 mRNA

NCBI chr18:77,984,886...78,030,837
Ensembl chr18:77,984,907...78,007,765

G

CTD nuclear envelope phosphatase 1 regulatory subunit 1

decreases expression

Sodium Selenite results in decreased expression of CNEP1R1 mRNA

NCBI chr19:18,932,631...18,947,667
Ensembl chr19:18,932,682...18,947,667

G

cytochrome c oxidase assembly factor 4 homolog

increases expression

Sodium Selenite results in increased expression of COA4 mRNA

NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174

G

cytochrome c oxidase assembly factor 8

increases expression

Sodium Selenite results in increased expression of COA8 mRNA

NCBI chr 6:130,772,218...130,797,081
Ensembl chr 6:130,771,199...130,797,081

G

Coenzyme A synthase

increases expression

Sodium Selenite results in increased expression of COASY mRNA

NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841

G

collagen type I alpha 1 chain

decreases expression
multiple interactions

Sodium Selenite results in decreased expression of COL1A1 mRNA
[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type XXVII alpha 1 chain

decreases expression

Sodium Selenite results in decreased expression of COL27A1 mRNA

NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174

G

collagen type II alpha 1 chain

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of COL2A1 mRNA
Sodium Selenite results in decreased expression of COL2A1 mRNA

NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546

G

collagen type III alpha 1 chain

decreases expression

Sodium Selenite results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

collagen type VI alpha 2 chain

increases expression
multiple interactions

Sodium Selenite results in increased expression of COL6A2 mRNA
[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of COL6A2 mRNA

PMID:18175754 PMID:23274088

NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564

G

COMM domain containing 8

increases expression

Sodium Selenite results in increased expression of COMMD8 mRNA

NCBI chr14:36,049,040...36,059,617
Ensembl chr14:36,049,004...36,059,617

G

COP9 signalosome subunit 2

increases expression

Sodium Selenite results in increased expression of COPS2 mRNA

NCBI chr 3:113,084,174...113,110,090
Ensembl chr 3:113,084,176...113,109,947

G

COP9 signalosome subunit 3

increases expression

Sodium Selenite results in increased expression of COPS3 mRNA

NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597

G

COP9 signalosome subunit 5

increases expression

Sodium Selenite results in increased expression of COPS5 mRNA

NCBI chr 5:9,192,233...9,210,498
Ensembl chr 5:9,192,100...9,210,731

G

COPI coat complex subunit zeta 1

increases expression

Sodium Selenite results in increased expression of COPZ1 mRNA

NCBI chr 7:134,409,523...134,435,661
Ensembl chr 7:134,409,799...134,435,662

G

coenzyme Q8B

increases expression

Sodium Selenite results in increased expression of COQ8B mRNA

NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180

G

coenzyme Q9

increases expression

Sodium Selenite results in increased expression of COQ9 mRNA

NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949

G

cytochrome c oxidase assembly factor COX14

increases expression

Sodium Selenite results in increased expression of COX14 mRNA

NCBI chr 7:130,852,226...130,854,316

G

cytochrome c oxidase assembly factor COX16

increases expression

Sodium Selenite results in increased expression of COX16 mRNA

NCBI chr 6:101,162,231...101,181,277
Ensembl chr 6:101,019,680...101,181,246

G

cytochrome c oxidase subunit 4i1

increases expression

Sodium Selenite results in increased expression of COX4I1 mRNA

NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921

G

cytochrome c oxidase subunit 5A

increases expression

Sodium Selenite results in increased expression of COX5A mRNA

NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781

G

cytochrome c oxidase subunit 6C

increases expression

Sodium Selenite results in increased expression of COX6C mRNA

NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963

G

cytochrome c oxidase subunit 8A

increases expression

Sodium Selenite results in increased expression of COX8A mRNA

NCBI chr 1:204,402,118...204,404,439

G

complexin 3

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of CPLX3 mRNA

NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297

G

cereblon

increases expression

Sodium Selenite results in increased expression of CRBN mRNA

NCBI chr 4:139,701,154...139,719,949
Ensembl chr 4:139,701,094...139,719,938

G

cAMP responsive element binding protein 3-like 4

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of CREB3L4 mRNA
Sodium Selenite results in decreased expression of CREB3L4 mRNA

NCBI chr 2:175,690,340...175,695,846
Ensembl chr 2:175,690,335...175,695,932

G

cAMP responsive element binding protein-like 2

increases expression

Sodium Selenite results in increased expression of CREBL2 mRNA

NCBI chr 4:167,673,359...167,699,299
Ensembl chr 4:167,673,315...167,699,292

G

corticotropin releasing hormone receptor 1

increases expression

Sodium Selenite results in increased expression of CRHR1 mRNA

NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481

G

collapsin response mediator protein 1

decreases expression

Sodium Selenite results in decreased expression of CRMP1 mRNA

NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177

G

C-reactive protein

affects expression

Sodium Selenite affects the expression of CRP protein

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

casein alpha s1

decreases expression

Sodium Selenite results in decreased expression of CSN1S1 mRNA

NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614

G

casein kinase 1, epsilon

increases expression

Sodium Selenite results in increased expression of CSNK1E mRNA

NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794

G

cysteine and serine rich nuclear protein 2

decreases expression

Sodium Selenite results in decreased expression of CSRNP2 mRNA

NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075

G

cysteine and glycine rich protein 3

decreases expression

Sodium Selenite results in decreased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cystatin A

increases expression

Sodium Selenite results in increased expression of CSTA mRNA

NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488

G

CST telomere replication complex component 1

decreases expression

Sodium Selenite results in decreased expression of CTC1 mRNA

NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298

G

CTD nuclear envelope phosphatase 1

increases expression

Sodium Selenite results in increased expression of CTDNEP1 mRNA

NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781

G

C-X3-C motif chemokine receptor 1

decreases expression

Sodium Selenite results in decreased expression of CX3CR1 mRNA

NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014

G

C-X-C motif chemokine ligand 12

multiple interactions

Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of CXCL12 mRNA]

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 2

increases expression

Sodium Selenite results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

CXXC finger protein 5

increases expression

Sodium Selenite results in increased expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

Sodium Selenite inhibits the reaction [cypermethrin results in decreased expression of CYP26B1 mRNA]

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 27, subfamily a, polypeptide 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 3

multiple interactions

Sodium Selenite inhibits the reaction [cypermethrin results in increased expression of CYP2B10 mRNA]

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily s, polypeptide 1

decreases expression

Sodium Selenite results in decreased expression of CYP2S1 mRNA

NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303

G

cytochrome P450, family 3, subfamily a, polypeptide 9

multiple interactions

Sodium Selenite inhibits the reaction [cypermethrin results in increased expression of CYP3A13 mRNA]

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

cytohesin 1 interacting protein

increases expression

Sodium Selenite results in increased expression of CYTIP mRNA

NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993

G

diacylglycerol lipase, beta

increases expression

Sodium Selenite results in increased expression of DAGLB mRNA

NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154

G

DALR anticodon binding domain containing 3

increases expression

Sodium Selenite results in increased expression of DALRD3 mRNA

NCBI chr 8:109,264,100...109,268,560
Ensembl chr 8:109,265,676...109,268,568

G

death associated protein 3

increases expression

Sodium Selenite results in increased expression of DAP3 mRNA

NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461

G

death associated protein kinase 1

decreases expression

Sodium Selenite results in decreased expression of DAPK1 mRNA

PMID:16705456 PMID:18175754

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

aspartyl-tRNA synthetase 1

increases expression

Sodium Selenite results in increased expression of DARS1 mRNA

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

death-domain associated protein

decreases expression

Sodium Selenite results in decreased expression of DAXX mRNA

NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843

G

DBF4B-CDC7 kinase regulatory subunit

decreases expression

Sodium Selenite results in decreased expression of DBF4B mRNA

NCBI chr10:87,713,805...87,719,197

G

diazepam binding inhibitor

increases expression

Sodium Selenite results in increased expression of DBI mRNA

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

G

dCTP pyrophosphatase 1

increases expression

Sodium Selenite results in increased expression of DCTPP1 mRNA

NCBI chr 1:181,877,440...181,880,833
Ensembl chr 1:181,877,437...181,880,839

G

DNA damage inducible 1 homolog 2

decreases expression

Sodium Selenite results in decreased expression of DDI2 mRNA

NCBI chr 5:153,989,591...154,035,342
Ensembl chr 5:153,995,589...154,035,283

G

DNA-damage inducible transcript 3

decreases expression
increases expression

Sodium Selenite results in decreased expression of DDIT3 mRNA
Sodium Selenite results in increased expression of DDIT3 mRNA; Sodium Selenite results in increased expression of DDIT3 protein

PMID:16705456 PMID:24383545 PMID:28161410 PMID:34520753

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4-like

decreases expression

Sodium Selenite results in decreased expression of DDIT4L mRNA

NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375

G

DDRGK domain containing 1

increases expression

Sodium Selenite results in increased expression of DDRGK1 mRNA

NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680

G

DEAD-box helicase 18

increases expression

Sodium Selenite results in increased expression of DDX18 mRNA

NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161

G

DEAD-box helicase 3, X-linked

increases expression

Sodium Selenite results in increased expression of DDX3X mRNA

NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168

G

DEAD box helicase 3, Y-linked

increases expression

Sodium Selenite results in increased expression of DDX3Y mRNA

NCBI chr Y:1,115,095...1,135,754
Ensembl chr Y:1,116,309...1,135,706

G

DEAD-box helicase 41

increases expression

Sodium Selenite results in increased expression of DDX41 mRNA

NCBI chr17:9,102,926...9,108,415
Ensembl chr17:9,103,010...9,108,415

G

DEAD-box helicase 47

increases expression

Sodium Selenite results in increased expression of DDX47 mRNA

NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115

G

DEP domain containing 5, GATOR1 subcomplex subunit

increases expression

Sodium Selenite results in increased expression of DEPDC5 mRNA

NCBI chr14:77,732,297...77,862,924
Ensembl chr14:77,732,297...77,862,794

G

DNA fragmentation factor subunit beta

decreases expression

Sodium Selenite results in decreased expression of DFFB mRNA

NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628

G

diacylglycerol kinase, alpha

increases expression

Sodium Selenite results in increased expression of DGKA mRNA

NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110

G

diacylglycerol kinase, theta

decreases expression

Sodium Selenite results in decreased expression of DGKQ mRNA

NCBI chr14:1,059,125...1,073,131
Ensembl chr14:1,059,170...1,073,131

G

diacylglycerol kinase zeta

increases expression

Sodium Selenite results in increased expression of DGKZ mRNA

NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099

G

dehydrogenase/reductase 9

multiple interactions

Sodium Selenite inhibits the reaction [cypermethrin results in decreased expression of DHRS9 mRNA]

NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241

G

DExH-box helicase 30

increases expression

Sodium Selenite results in increased expression of DHX30 mRNA

NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381

G

DEAH-box helicase 36

increases expression

Sodium Selenite results in increased expression of DHX36 mRNA

NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572

G

DIM1 rRNA methyltransferase and ribosome maturation factor

increases expression

Sodium Selenite results in increased expression of DIMT1 mRNA

NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:38,354,854...38,368,227

G

iodothyronine deiodinase 2

multiple interactions

Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Colforsin results in increased activity of DIO2 protein]]

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

iodothyronine deiodinase 3

multiple interactions

Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein]

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

dyskerin pseudouridine synthase 1

increases expression

Sodium Selenite results in increased expression of DKC1 mRNA

G

discs large MAGUK scaffold protein 4

decreases expression

Sodium Selenite results in decreased expression of DLG4 mRNA

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

DLG associated protein 2

decreases expression

Sodium Selenite results in decreased expression of DLGAP2 mRNA

NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407

G

delta like non-canonical Notch ligand 2

increases expression

Sodium Selenite results in increased expression of DLK2 mRNA

NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594

G

DM1 locus, WD repeat containing

increases expression

Sodium Selenite results in increased expression of DMWD mRNA

NCBI chr 1:78,722,436...78,729,224
Ensembl chr 1:78,722,330...78,740,593

G

DNA methyltransferase 1

decreases expression

Sodium Selenite results in decreased expression of DNMT1 mRNA; Sodium Selenite results in decreased expression of DNMT1 protein

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

decreases expression

Sodium Selenite results in decreased expression of DNMT3A mRNA

PMID:18676679 PMID:37142062

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 beta

increases expression

Sodium Selenite results in increased expression of DNMT3B mRNA

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

aspartyl aminopeptidase

increases expression

Sodium Selenite results in increased expression of DNPEP mRNA

NCBI chr 9:76,799,931...76,808,841
Ensembl chr 9:76,783,966...76,808,716

G

2'-deoxynucleoside 5'-phosphate N-hydrolase 1

increases expression

Sodium Selenite results in increased expression of DNPH1 mRNA

NCBI chr 9:14,481,296...14,484,034
Ensembl chr 9:14,481,066...14,484,022

G

deoxynucleotidyltransferase, terminal, interacting protein 2

increases expression

Sodium Selenite results in increased expression of DNTTIP2 mRNA

NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581

G

dedicator of cytokinesis 4

decreases expression

Sodium Selenite results in decreased expression of DOCK4 mRNA

NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855

G

diphthamide biosynthesis 3

increases expression

Sodium Selenite results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dipeptidylpeptidase 3

increases expression

Sodium Selenite results in increased expression of DPP3 mRNA

NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541

G

DNA-damage regulated autophagy modulator 1

decreases expression

Sodium Selenite results in decreased expression of DRAM1 mRNA

NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765

G

desmocollin 2

decreases expression

Sodium Selenite results in decreased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

dynein, cytoplasmic 1 light intermediate chain 2

decreases expression

Sodium Selenite results in decreased expression of DYNC1LI2 mRNA

NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670

G

dynein cytoplasmic 2 light intermediate chain 1

increases expression

Sodium Selenite results in increased expression of DYNC2LI1 mRNA

NCBI chr 6:9,992,537...10,025,355
Ensembl chr 6:9,992,541...10,025,336

G

dynein light chain Tctex-type 3

increases expression

Sodium Selenite results in increased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

E2F transcription factor 3

decreases expression

Sodium Selenite results in decreased expression of E2F3 mRNA

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

EBF transcription factor 1

decreases expression

Sodium Selenite results in decreased expression of EBF1 mRNA

NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665

G

EBP like

increases expression

Sodium Selenite results in increased expression of EBPL mRNA

NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472

G

enoyl-CoA hydratase 1

increases expression

Sodium Selenite results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

ECSIT signaling integrator

increases expression

Sodium Selenite results in increased expression of ECSIT mRNA

NCBI chr 8:20,605,583...20,618,453
Ensembl chr 8:20,605,583...20,618,390

G

ectodysplasin A2 receptor

increases expression

Sodium Selenite results in increased expression of EDA2R mRNA

NCBI chr X:62,224,763...62,269,333
Ensembl chr X:62,228,229...62,269,268

G

endothelin receptor type A

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of EDNRA mRNA

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

G

erythroid differentiation regulatory factor 1

decreases expression

Sodium Selenite results in decreased expression of EDRF1 mRNA

NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701

G

EEF1A lysine methyltransferase 3

decreases expression

Sodium Selenite results in decreased expression of EEF1AKMT3 mRNA

NCBI chr 7:62,853,304...62,864,558
Ensembl chr 7:62,854,899...62,864,617

G

eukaryotic translation elongation factor 1 epsilon 1

increases expression

Sodium Selenite results in increased expression of EEF1E1 mRNA

NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720

G

eukaryotic translation elongation factor 2

increases expression

Sodium Selenite results in increased expression of EEF2 mRNA

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

EF-hand calcium binding domain 14

increases expression

Sodium Selenite results in increased expression of EFCAB14 mRNA

NCBI chr 5:129,218,139...129,258,628
Ensembl chr 5:129,218,424...129,258,625

G

epidermal growth factor

multiple interactions

Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in decreased expression of EGF mRNA]

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

decreases expression

Sodium Selenite results in decreased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

early growth response 1

increases expression
multiple interactions

Sodium Selenite results in increased expression of EGR1 mRNA
Acetylcarnitine inhibits the reaction [Sodium Selenite results in increased expression of EGR1 mRNA]

PMID:18175754 PMID:20067779

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 4

decreases expression

Sodium Selenite results in decreased expression of EGR4 mRNA

NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328

G

EI24, autophagy associated transmembrane protein

increases expression

Sodium Selenite results in increased expression of EI24 mRNA

NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571

G

EP300 interacting inhibitor of differentiation 2

increases expression

Sodium Selenite results in increased expression of EID2 mRNA

NCBI chr 1:83,538,274...83,539,599

G

eukaryotic translation initiation factor 2 alpha kinase 3

decreases expression

Sodium Selenite results in decreased expression of EIF2AK3 protein

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

increases phosphorylation
multiple interactions

Sodium Selenite results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Sodium Selenite results in increased phosphorylation of EIF2S1 protein]

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 3, subunit A

increases expression

Sodium Selenite results in increased expression of EIF3A mRNA

NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976

G

eukaryotic translation initiation factor 3, subunit H

increases expression

Sodium Selenite results in increased expression of EIF3H mRNA

NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451

G

eukaryotic translation initiation factor 4A3

increases expression

Sodium Selenite deficiency results in increased expression of EIF4A3 protein

NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057

G

eukaryotic translation initiation factor 4B

increases expression

Sodium Selenite results in increased expression of EIF4B mRNA

NCBI chr 7:133,206,637...133,228,436

G

eukaryotic translation initiation factor 4E binding protein 2

increases expression

Sodium Selenite results in increased expression of EIF4EBP2 mRNA

NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946

G

eukaryotic translation initiation factor 4 gamma 1

increases expression

Sodium Selenite results in increased expression of EIF4G1 mRNA

NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941

G

eukaryotic translation initiation factor 4, gamma 2

increases expression

Sodium Selenite results in increased expression of EIF4G2 mRNA

NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588

G

eukaryotic translation initiation factor 4H

increases expression

Sodium Selenite results in increased expression of EIF4H mRNA

NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876

G

eukaryotic translation initiation factor 5B

increases expression

Sodium Selenite results in increased expression of EIF5B mRNA

NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

decreases expression

Sodium Selenite results in decreased expression of ELFN2 mRNA

NCBI chr 7:110,220,293...110,272,770
Ensembl chr 7:110,225,919...110,272,433

G

elongator acetyltransferase complex subunit 3

increases expression

Sodium Selenite results in increased expression of ELP3 mRNA

NCBI chr15:39,754,635...39,816,482
Ensembl chr15:39,754,632...39,816,445

G

embigin

increases expression

Sodium Selenite results in increased expression of EMB mRNA

NCBI chr 2:49,070,509...49,125,042
Ensembl chr 2:49,069,087...49,125,050

G

ER membrane protein complex subunit 10

increases expression

Sodium Selenite results in increased expression of EMC10 mRNA

NCBI chr 1:94,980,260...94,988,847
Ensembl chr 1:94,943,587...94,988,847

G

ER membrane protein complex subunit 3

decreases expression

Sodium Selenite results in decreased expression of EMC3 mRNA

NCBI chr 4:146,663,065...146,678,976
Ensembl chr 4:146,663,067...146,679,029

G

ER membrane protein complex subunit 8

increases expression

Sodium Selenite results in increased expression of EMC8 mRNA

NCBI chr19:48,708,304...48,721,626
Ensembl chr19:48,582,574...48,721,543

G

elastin microfibril interfacer 3

decreases expression

Sodium Selenite results in decreased expression of EMILIN3 mRNA

NCBI chr 3:149,558,785...149,564,785
Ensembl chr 3:149,558,970...149,564,785

G

engrailed homeobox 2

increases expression

Sodium Selenite results in increased expression of EN2 mRNA

NCBI chr 4:7,221,096...7,226,943
Ensembl chr 4:7,221,096...7,226,943

G

glutamyl aminopeptidase

decreases expression

Sodium Selenite results in decreased expression of ENPEP mRNA

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleoside triphosphate diphosphohydrolase 7

decreases expression

Sodium Selenite results in decreased expression of ENTPD7 mRNA

NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447

G

endosome associated trafficking regulator 1

increases expression

Sodium Selenite results in increased expression of ENTR1 mRNA

NCBI chr 3:9,200,967...9,207,688
Ensembl chr 3:9,200,967...9,207,688

G

E1A binding protein p300

decreases expression

Sodium Selenite results in decreased expression of EP300 mRNA; Sodium Selenite results in decreased expression of EP300 protein

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

endothelial PAS domain protein 1

increases expression

Sodium Selenite results in increased expression of EPAS1 mRNA

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

EGFR pathway substrate 8, signaling adaptor

decreases expression

Sodium Selenite results in decreased expression of EPS8 mRNA

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

Sodium Selenite results in increased expression of ERCC1 mRNA

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 3, TFIIH core complex helicase subunit

increases expression

Sodium Selenite results in increased expression of ERCC3 mRNA

NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329

G

epiregulin

increases expression

Sodium Selenite results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ER lipid raft associated 1

increases expression

Sodium Selenite results in increased expression of ERLIN1 mRNA

NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394

G

estrogen receptor 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

affects expression

Sodium Selenite affects the expression of ESR2 mRNA

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

extended synaptotagmin 2

increases expression

Sodium Selenite results in increased expression of ESYT2 mRNA

NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590

G

electron transfer flavoprotein subunit beta

increases expression

Sodium Selenite results in increased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

electron transfer flavoprotein dehydrogenase

increases expression

Sodium Selenite results in increased expression of ETFDH mRNA

NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745

G

exo/endonuclease G

decreases expression

Sodium Selenite results in decreased expression of EXOG mRNA

NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672

G

exosome component 6

increases expression

Sodium Selenite results in increased expression of EXOSC6 mRNA

NCBI chr19:39,022,171...39,023,585
Ensembl chr19:39,022,183...39,023,515

G

exostosin glycosyltransferase 2

increases expression

Sodium Selenite results in increased expression of EXT2 mRNA

NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

increases expression

Sodium Selenite results in increased expression of EZH1 mRNA

NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921

G

coagulation factor II (thrombin) receptor-like 2

increases expression

Sodium Selenite results in increased expression of F2RL2 mRNA

NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098

G

coagulation factor VIII-associated 1

increases expression

Sodium Selenite results in increased expression of F8A1 mRNA

NCBI chr X:150,957,357...150,958,871
Ensembl chr X:150,916,679...150,960,168

G

FA core complex associated protein 100

increases expression

Sodium Selenite results in increased expression of FAAP100 mRNA

NCBI chr10:105,641,677...105,653,809
Ensembl chr10:105,639,414...105,653,494

G

fatty acid binding protein 4

increases expression
multiple interactions

Sodium Selenite results in increased expression of FABP4 mRNA
Sodium Selenite inhibits the reaction [citreoviridin results in decreased expression of FABP4 mRNA]

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

Fas associated factor 1

increases expression

Sodium Selenite results in increased expression of FAF1 mRNA

NCBI chr 5:124,426,032...124,790,014
Ensembl chr 5:124,426,062...124,789,977

G

family with sequence similarity 117, member A

increases expression

Sodium Selenite results in increased expression of FAM117A mRNA

NCBI chr10:80,281,411...80,325,345
Ensembl chr10:80,281,408...80,325,343

G

family with sequence similarity 135, member B

increases expression

Sodium Selenite results in increased expression of FAM135B mRNA

NCBI chr 7:103,380,981...103,649,802
Ensembl chr 7:103,386,915...103,649,708

G

family with sequence similarity 162, member A

increases expression

Sodium Selenite results in increased expression of FAM162A mRNA

NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239

G

family with sequence similarity 98, member C

increases expression

Sodium Selenite results in increased expression of FAM98C mRNA

NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases expression

Sodium Selenite results in decreased expression of FARP1 mRNA

NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299

G

phenylalanyl-tRNA synthetase subunit beta

increases expression

Sodium Selenite results in increased expression of FARSB mRNA

NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045

G

fatty acid synthase

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 2

decreases expression

Sodium Selenite results in decreased expression of FAT2 mRNA

NCBI chr10:39,364,072...39,456,324
Ensembl chr10:39,364,073...39,456,216

G

fibrillarin

increases expression

Sodium Selenite results in increased expression of FBL mRNA

NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932

G

F-box and leucine-rich repeat protein 12

increases expression

Sodium Selenite results in increased expression of FBXL12 mRNA

NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607

G

F-box and leucine-rich repeat protein 5

increases expression

Sodium Selenite results in increased expression of FBXL5 mRNA

NCBI chr14:67,305,109...67,347,383
Ensembl chr14:67,267,801...67,347,383

G

F-box protein 32

increases expression

Sodium Selenite results in increased expression of FBXO32 mRNA

PMID:18175754 PMID:24383545

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 5

decreases expression

Sodium Selenite results in decreased expression of FBXO5 mRNA

NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437

G

Fc epsilon receptor Ia

increases expression

Sodium Selenite results in increased expression of FCER1A mRNA

NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351

G

ferredoxin reductase

increases expression

Sodium Selenite results in increased expression of FDXR mRNA

NCBI chr10:100,507,863...100,516,649
Ensembl chr10:100,507,865...100,516,658

G

FERM domain containing kindlin 2

decreases expression

Sodium Selenite results in decreased expression of FERMT2 mRNA

PMID:18175754 PMID:23274088

NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811

G

fasciculation and elongation protein zeta 1

increases expression

Sodium Selenite results in increased expression of FEZ1 mRNA

NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683

G

fibroblast growth factor receptor 2

multiple interactions

Sodium Selenite promotes the reaction [Hydrogen Peroxide results in decreased expression of FGFR2 mRNA]

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

four and a half LIM domains 2

increases expression

Sodium Selenite results in increased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

Fms related receptor tyrosine kinase 1

decreases expression

Sodium Selenite results in decreased expression of FLT1 mRNA

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

formin 2

increases expression

Sodium Selenite results in increased expression of FMN2 mRNA

NCBI chr13:86,454,256...86,771,437
Ensembl chr13:86,453,926...86,771,411

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

Sodium Selenite results in decreased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

formin binding protein 1

increases expression

Sodium Selenite results in increased expression of FNBP1 mRNA

NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881

G

formin binding protein 1-like

decreases expression

Sodium Selenite results in decreased expression of FNBP1L mRNA

NCBI chr 2:210,647,241...210,748,203
Ensembl chr 2:210,647,246...210,738,455

G

farnesyltransferase, CAAX box, subunit alpha

increases expression

Sodium Selenite results in increased expression of FNTA mRNA

NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Sodium Selenite results in increased expression of FOS mRNA
Buthionine Sulfoximine inhibits the reaction [Sodium Selenite results in increased expression of FOS mRNA]; Glutathione affects the reaction [Sodium Selenite results in increased expression of FOS mRNA]
Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]
Sodium Selenite results in increased expression of FOS protein
[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of FOS mRNA; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of FOS protein

PMID:11769627 PMID:16542727 PMID:16944776 PMID:18175754 PMID:18449455 More...

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box O1

multiple interactions

Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein]

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

forkhead box P1

increases expression

Sodium Selenite results in increased expression of FOXP1 mRNA

NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258

G

FAD-dependent oxidoreductase domain containing 2

decreases expression

Sodium Selenite results in decreased expression of FOXRED2 mRNA

NCBI chr 7:109,521,761...109,538,300
Ensembl chr 7:109,521,761...109,540,874

G

fibroblast growth factor receptor substrate 2

decreases expression

Sodium Selenite results in decreased expression of FRS2 mRNA

NCBI chr 7:52,711,255...52,792,738
Ensembl chr 7:52,711,257...52,792,743

G

follicle stimulating hormone subunit beta

multiple interactions

Sodium Selenite inhibits the reaction [sodium arsenite results in decreased expression of FSHB protein]

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

follistatin-like 1

multiple interactions

Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of FSTL1 protein]

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

Fus RNA binding protein

affects localization
multiple interactions

Sodium Selenite affects the localization of FUS protein
Sodium Selenite promotes the reaction [TUBA4A protein binds to FUS protein]

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

fucosyltransferase 4, pseudogene 1

decreases expression

Sodium Selenite results in decreased expression of FUT6 mRNA

NCBI chr 9:1,569,605...1,572,022

G

fucosyltransferase 7

decreases expression

Sodium Selenite results in decreased expression of FUT7 mRNA

NCBI chr 3:8,237,687...8,242,273
Ensembl chr 3:8,239,384...8,242,260

G

FXYD domain-containing ion transport regulator 5

increases expression

Sodium Selenite results in increased expression of FXYD5 mRNA

NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519

G

frizzled class receptor 1

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of FZD1 mRNA
Sodium Selenite results in decreased expression of FZD1 mRNA

NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

glucose-6-phosphatase catalytic subunit 1

multiple interactions

Sodium Selenite inhibits the reaction [Alloxan results in increased activity of G6PC1 protein]
Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA]

PMID:25779343 PMID:26522834

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

GRB2-associated binding protein 1

decreases expression

Sodium Selenite results in decreased expression of GAB1 mRNA

NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236

G

glutamate decarboxylase 1

decreases expression

Sodium Selenite results in decreased expression of GAD1 mRNA

NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333

G

growth arrest and DNA-damage-inducible, alpha

decreases expression

Sodium Selenite results in decreased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

cyclin G associated kinase

increases expression

Sodium Selenite results in increased expression of GAK mRNA

NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398

G

polypeptide N-acetylgalactosaminyltransferase 1

increases expression

Sodium Selenite results in increased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

polypeptide N-acetylgalactosaminyltransferase 11

increases expression

Sodium Selenite results in increased expression of GALNT11 mRNA

NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140

G

galanin receptor 3

increases expression

Sodium Selenite results in increased expression of GALR3 mRNA

NCBI chr 7:110,603,525...110,608,429
Ensembl chr 7:110,605,226...110,607,685

G

glycyl-tRNA synthetase 1

increases expression

Sodium Selenite results in increased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest specific 6

increases expression

Sodium Selenite results in increased expression of GAS6 mRNA

NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904

G

GATA binding protein 3

increases expression

Sodium Selenite results in increased expression of GATA3 mRNA

NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391

G

glycine amidinotransferase

decreases expression

Sodium Selenite results in decreased expression of GATM mRNA

NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129

G

glucosylceramidase beta 3

decreases expression

Sodium Selenite results in decreased expression of GBA3 mRNA

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

gastrulation brain homeobox 2

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of GBX2 mRNA

NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212

G

GRIP and coiled-coil domain containing 1

increases expression

Sodium Selenite results in increased expression of GCC1 mRNA

NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663

G

glutamate-cysteine ligase, catalytic subunit

increases expression

Sodium Selenite results in increased expression of GCLC mRNA

PMID:18449455 PMID:24383545

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glucosaminyl (N-acetyl) transferase 3, mucin type

decreases expression

Sodium Selenite results in decreased expression of GCNT3 mRNA

NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562

G

growth differentiation factor 15

increases expression

Sodium Selenite results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

glial cell derived neurotrophic factor

multiple interactions

Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDNF mRNA]

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

glial fibrillary acidic protein

multiple interactions
decreases expression

Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in increased expression of GFAP mRNA]
Sodium Selenite results in decreased expression of GFAP mRNA

PMID:17997286 PMID:18209489

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

geranylgeranyl diphosphate synthase 1

increases expression

Sodium Selenite results in increased expression of GGPS1 mRNA

NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220

G

growth hormone receptor

decreases expression

Sodium Selenite results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

GTPase, IMAP family member 1

increases expression

Sodium Selenite results in increased expression of GIMAP1 mRNA

NCBI chr 4:77,687,581...77,691,468
Ensembl chr 4:77,682,171...77,691,866

G

gap junction protein, beta 4

increases expression

Sodium Selenite results in increased expression of GJB4 mRNA

NCBI chr 5:139,675,776...139,679,551
Ensembl chr 5:139,675,780...139,679,667

G

golgi glycoprotein 1

increases expression

Sodium Selenite results in increased expression of GLG1 mRNA

NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178

G

GLI family zinc finger 2

decreases expression

Sodium Selenite results in decreased expression of GLI2 mRNA

NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574

G

glyoxalase domain containing 4

increases expression

Sodium Selenite results in increased expression of GLOD4 mRNA

NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898

G

glutamate dehydrogenase 1

increases expression

Sodium Selenite results in increased expression of GLUD1 mRNA

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

glia maturation factor, gamma

increases expression

Sodium Selenite results in increased expression of GMFG mRNA

NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183

G

geminin, DNA replication inhibitor

decreases expression

Sodium Selenite results in decreased expression of GMNN mRNA

NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054

G

guanine monophosphate synthase

increases expression

Sodium Selenite results in increased expression of GMPS mRNA

NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875

G

golgin A5

increases expression

Sodium Selenite results in increased expression of GOLGA5 mRNA

NCBI chr 6:121,612,389...121,640,552
Ensembl chr 6:121,612,529...121,640,413

G

golgin A7

increases expression

Sodium Selenite results in increased expression of GOLGA7 mRNA

NCBI chr16:68,767,259...68,782,536
Ensembl chr16:68,767,299...68,782,511

G

gon-4 like

decreases expression

Sodium Selenite results in decreased expression of GON4L mRNA

NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634

G

glutamic-oxaloacetic transaminase 1

increases expression

Sodium Selenite results in increased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

G patch domain containing 11

decreases expression

Sodium Selenite results in decreased expression of GPATCH11 mRNA

NCBI chr 6:16,229,933...16,243,305
Ensembl chr 6:16,233,059...16,243,238

G

GC-rich promoter binding protein 1

increases expression

Sodium Selenite results in increased expression of GPBP1 mRNA

NCBI chr 2:43,023,504...43,091,146
Ensembl chr 2:43,023,504...43,090,907

G

glypican 1

increases expression

Sodium Selenite results in increased expression of GPC1 mRNA

NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047

G

G protein-coupled estrogen receptor 1

increases expression

Sodium Selenite results in increased expression of GPER1 protein

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glycoprotein hormone subunit beta 5

increases expression

Sodium Selenite results in increased expression of GPHB5 mRNA

NCBI chr 6:94,129,968...94,134,585
Ensembl chr 6:94,131,021...94,133,570

G

G protein-coupled receptor 132

increases expression

Sodium Selenite results in increased expression of GPR132 mRNA

NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168

G

G protein-coupled receptor 161

decreases expression

Sodium Selenite results in decreased expression of GPR161 mRNA

NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613

G

G protein-coupled receptor 19

decreases expression

Sodium Selenite results in decreased expression of GPR19 mRNA

NCBI chr 4:167,710,944...167,739,232
Ensembl chr 4:167,710,666...167,741,036

G

G protein-coupled receptor 39

decreases expression

Sodium Selenite results in decreased expression of GPR39 mRNA

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

G

G-protein coupled receptor 65

increases expression

Sodium Selenite results in increased expression of GPR65 mRNA

NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512

G

glutamic--pyruvic transaminase

increases expression
multiple interactions

Sodium Selenite results in increased expression of GPT mRNA
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]; Sodium Selenite inhibits the reaction [Matrines results in increased expression of GPT protein]

PMID:18175754 PMID:30031400 PMID:36464106 PMID:37716422

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions
affects activity
affects expression
increases expression
increases activity
decreases expression
increases expression

GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased activity of GPX1 protein]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased expression of GPX1 protein]
SEPHS1 protein affects the reaction [Sodium Selenite results in increased expression of GPX1 protein]; Sodium Selenite affects the reaction [GPX1 gene mutant form affects the susceptibility to Paraquat]; Sodium Selenite inhibits the reaction [Diethylhexyl Phthalate results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]
Sodium Selenite affects the activity of GPX1 protein
Sodium Selenite affects the expression of GPX1 mRNA
[Sodium Selenite co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [cholestane-3,5,6-triol results in increased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein]; Sodium Selenite inhibits the reaction [sodium arsenite results in increased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased activity of GPX1 protein]
Sodium Selenite results in increased expression of GPX1 mRNA; Sodium Selenite results in increased expression of GPX1 protein
Sodium Selenite deficiency results in decreased expression of GPX1 protein
Sodium selenite increases expression of GPX1 protein in epithelial cells

CTD
RGD

PMID:12449240 PMID:12654481 PMID:12667700 PMID:12896980 PMID:15203190 More...

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression

Sodium Selenite results in increased expression of GPX2 protein

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 3

multiple interactions
increases expression
increases activity

GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased activity of GPX3 protein]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased expression of GPX3 protein]

PMID:16952904 PMID:17536041 PMID:18400727

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 4

multiple interactions
affects response to substance
affects activity
affects expression
increases expression

alpha-Tocopherol inhibits the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]; Arachidonic Acid promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein]; Docosahexaenoic Acids inhibits the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein]; Docosahexaenoic Acids promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased activity of GPX1 protein]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased activity of GPX3 protein]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased expression of GPX1 protein]; GPX4 gene SNP inhibits the reaction [Sodium Selenite results in increased expression of GPX3 protein]; IL1B protein promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein]; IL1B protein promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]; Linoleic Acids, Conjugated promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]; Sodium Selenite inhibits the reaction [Matrines results in decreased expression of GPX4 protein]; Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein; TNF protein affects the reaction [Sodium Selenite results in increased activity of GPX4 protein]; TNF protein affects the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]
GPX4 gene SNP affects the susceptibility to Sodium Selenite
Sodium Selenite affects the activity of GPX4 protein polymorphism
Sodium Selenite affects the expression of GPX4 protein polymorphism
Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of GPX4 mRNA]; Sodium Selenite inhibits the reaction [sodium aescinate results in decreased expression of GPX4 protein]
Sodium Selenite results in increased expression of GPX4 mRNA; Sodium Selenite results in increased expression of GPX4 protein
Sodium Selenite inhibits the reaction [Selenium deficiency results in decreased expression of GPX4 protein]; Sodium Selenite inhibits the reaction [sodium aescinate results in decreased expression of GPX4 protein]

PMID:14642406 PMID:18400727 PMID:18514395 PMID:20643113 PMID:34970773 More...

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

GRAM domain containing 1B

decreases expression

Sodium Selenite results in decreased expression of GRAMD1B mRNA

NCBI chr 8:40,654,492...40,893,869
Ensembl chr 8:40,659,182...40,893,925

G

GRAM domain containing 2B

decreases expression

Sodium Selenite results in decreased expression of GRAMD2B mRNA

NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953

G

GRAM domain containing 4

decreases expression

Sodium Selenite results in decreased expression of GRAMD4 mRNA

NCBI chr 7:117,150,398...117,224,056
Ensembl chr 7:117,150,374...117,224,053

G

growth factor receptor bound protein 10

decreases expression

Sodium Selenite results in decreased expression of GRB10 mRNA

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

growth factor receptor bound protein 2

decreases expression
increases expression

Sodium Selenite results in decreased expression of GRB2 mRNA
Sodium Selenite results in increased expression of GRB2 mRNA

PMID:16705456 PMID:18175754

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

G

grainyhead-like transcription factor 1

decreases expression

Sodium Selenite results in decreased expression of GRHL1 mRNA

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

G

glutamate ionotropic receptor kainate type subunit 1

increases expression

Sodium Selenite results in increased expression of GRIK1 mRNA

NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645

G

glutamate ionotropic receptor kainate type subunit 3

increases expression

Sodium Selenite results in increased expression of GRIK3 mRNA

NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307

G

G protein-coupled receptor kinase 6

increases expression

Sodium Selenite results in increased expression of GRK6 mRNA

NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644

G

glycogen synthase kinase 3 beta

decreases expression

Sodium Selenite results in decreased expression of GSK3B mRNA

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

GSK3B interacting protein

increases expression

Sodium Selenite results in increased expression of GSKIP mRNA

NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100

G

glutathione-disulfide reductase

increases expression
multiple interactions
increases activity
decreases activity

Sodium Selenite results in increased expression of GSR protein
lupeol inhibits the reaction [Sodium Selenite results in decreased activity of GSR protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]
Methylmercury Compounds inhibits the reaction [Sodium Selenite results in increased activity of GSR protein]

PMID:20620206 PMID:21215776 PMID:22476978 PMID:26697995

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase kappa 1

increases expression

Sodium Selenite results in increased expression of GSTK1 mRNA

NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292

G

glutathione S-transferase, mu 5

increases expression

Sodium Selenite results in increased expression of GSTM3 mRNA

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glutathione S-transferase omega 1

decreases expression

Sodium Selenite results in decreased expression of GSTO1 mRNA

NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468

G

glutathione S-transferase pi 1

multiple interactions
decreases methylation
increases expression

Sodium Selenite affects the reaction [H3-4 protein modified form binds to GSTP1 promoter]; Sodium Selenite inhibits the reaction [GSTP1 protein SNP binds to and results in increased glutathionylation of Dinitrochlorobenzene]
Sodium Selenite results in decreased methylation of GSTP1 promoter
Sodium Selenite results in increased expression of GSTP1 mRNA; Sodium Selenite results in increased expression of GSTP1 protein

PMID:18676679 PMID:22401947

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 1

increases expression

Sodium Selenite results in increased expression of GSTT1 mRNA

PMID:16705456 PMID:24383545

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

general transcription factor IIF subunit 2

increases expression

Sodium Selenite results in increased expression of GTF2F2 mRNA

NCBI chr15:51,206,027...51,327,166
Ensembl chr15:51,206,031...51,327,253

G

GTP binding protein 4

increases expression

Sodium Selenite results in increased expression of GTPBP4 mRNA

NCBI chr17:61,308,033...61,328,184
Ensembl chr17:61,308,014...61,418,009

G

GTP binding protein 6 (putative)

increases expression

Sodium Selenite results in increased expression of GTPBP6 mRNA

NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873

G

guanylate cyclase 1 soluble subunit alpha 1

decreases expression

Sodium Selenite results in decreased expression of GUCY1A1 mRNA

NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671

G

GULP PTB domain containing engulfment adaptor 1

decreases expression

Sodium Selenite results in decreased expression of GULP1 mRNA

NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005

G

granzyme K

increases expression

Sodium Selenite results in increased expression of GZMK mRNA

NCBI chr 2:44,840,811...44,848,829
Ensembl chr 2:44,840,811...44,848,894

G

H1.0 linker histone

decreases expression

Sodium Selenite results in decreased expression of H1-0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.X variant histone

increases expression

Sodium Selenite results in increased expression of H2AX mRNA
Sodium Selenite results in increased expression of H2AX protein

PMID:18175754 PMID:37142062

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

H2A.Z variant histone 2

increases expression

Sodium Selenite results in increased expression of H2AZ2 mRNA

NCBI chr14:81,293,304...81,312,209
Ensembl chr14:81,293,299...81,312,144

G

H2B clustered histone 6

decreases expression

Sodium Selenite results in decreased expression of H2BC6 mRNA

NCBI chr17:41,520,775...41,521,238

G

H3.4 histone, cluster member

multiple interactions
increases acetylation
decreases methylation

Sodium Selenite affects the reaction [H3-4 protein modified form binds to GSTP1 promoter]
Sodium Selenite results in increased acetylation of H3-4
Sodium Selenite results in decreased methylation of H3-4

NCBI chr10:43,740,702...43,741,262

G

H4 clustered histone 14

decreases expression

Sodium Selenite results in decreased expression of H4C2 mRNA

NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

Sodium Selenite results in increased expression of HADHA mRNA

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

HAUS augmin-like complex, subunit 3

increases expression

Sodium Selenite results in increased expression of HAUS3 mRNA

NCBI chr14:76,580,549...76,599,542
Ensembl chr14:76,580,546...76,752,463

G

hepatitis A virus cellular receptor 1

multiple interactions

Sodium Selenite inhibits the reaction [sodium aescinate results in increased expression of HAVCR1]

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

HCLS1 associated protein X-1

increases expression

Sodium Selenite results in increased expression of HAX1 mRNA

NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714

G

hemoglobin subunit epsilon 1

decreases expression

Sodium Selenite results in decreased expression of HBE1 mRNA

NCBI chr 1:158,282,931...158,458,855
Ensembl chr 1:158,282,936...158,284,391

G

hemoglobin subunit gamma 1

decreases expression

Sodium Selenite results in decreased expression of HBG1 mRNA

NCBI chr 1:158,271,871...158,273,426
Ensembl chr 1:158,271,873...158,273,425

G

hemoglobin subunit theta 1B

decreases expression

Sodium Selenite results in decreased expression of HBQ1 mRNA

NCBI chr10:15,334,293...15,336,061
Ensembl chr10:15,320,762...15,321,397
Ensembl chr10:15,320,762...15,321,397

G

HBS1-like translational GTPase

increases expression

Sodium Selenite results in increased expression of HBS1L mRNA

NCBI chr 1:16,092,529...16,170,082
Ensembl chr 1:16,092,547...16,170,074

G

hypocretin neuropeptide precursor

increases expression

Sodium Selenite results in increased expression of HCRT mRNA

NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210

G

histone deacetylase 3

decreases expression

Sodium Selenite results in decreased expression of HDAC3 protein

NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856

G

histone deacetylase 7

increases expression

Sodium Selenite results in increased expression of HDAC7 mRNA

NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072

G

HEAT repeat containing 1

increases expression

Sodium Selenite results in increased expression of HEATR1 mRNA

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

heme binding protein 2

increases expression

Sodium Selenite results in increased expression of HEBP2 mRNA

NCBI chr 1:13,194,982...13,201,777
Ensembl chr 1:13,194,982...13,201,777

G

hdc homolog, cell cycle regulator

increases expression

Sodium Selenite results in increased expression of HECA mRNA

NCBI chr 1:12,525,445...12,575,358
Ensembl chr 1:12,525,135...12,576,427

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

decreases expression

Sodium Selenite results in decreased expression of HERC6 mRNA

NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744

G

hes family bHLH transcription factor 2

decreases expression

Sodium Selenite results in decreased expression of HES2 mRNA

NCBI chr 5:162,667,190...162,668,235
Ensembl chr 5:162,667,190...162,668,235

G

hepatocyte growth factor

multiple interactions
decreases expression

Sodium Selenite inhibits the reaction [TGFB1 protein results in increased expression of HGF protein]
Sodium Selenite results in decreased expression of HGF mRNA
[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of HGF mRNA

PMID:16757516 PMID:18175754 PMID:23274088

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

HIC ZBTB transcriptional repressor 1

multiple interactions
increases expression

[ptaquiloside co-treated with Sodium Selenite] results in increased expression of HIC1 mRNA
Sodium Selenite results in increased expression of HIC1 mRNA

NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475

G

histidine triad nucleotide binding protein 1

increases expression

Sodium Selenite results in increased expression of HINT1 mRNA

NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568

G

homeodomain interacting protein kinase 2

decreases expression

Sodium Selenite results in decreased expression of HIPK2 mRNA

NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223

G

homeobox containing 1

increases expression

Sodium Selenite results in increased expression of HMBOX1 mRNA

NCBI chr15:39,067,805...39,200,633
Ensembl chr15:39,067,804...39,200,323

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]

PMID:30031400 PMID:36464106

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

high mobility group nucleosome binding domain 5

decreases expression

Sodium Selenite results in decreased expression of HMGN5 mRNA

NCBI chr X:74,085,871...74,094,488
Ensembl chr X:74,085,875...74,094,441

G

heme oxygenase 1

multiple interactions

[zinc chloride co-treated with Sodium Selenite] inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein]; Sodium Selenite inhibits the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in decreased expression of HMOX1 protein]; Sodium Selenite inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Sodium Selenite inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 mRNA]; Sodium Selenite inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 protein]

PMID:23603382 PMID:36646412 PMID:36736877

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heme oxygenase 2

increases expression

Sodium Selenite results in increased expression of HMOX2 mRNA

NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148

G

heterogeneous nuclear ribonucleoprotein D

increases expression

Sodium Selenite results in increased expression of HNRNPD mRNA

NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786

G

heterogeneous nuclear ribonucleoprotein K

increases expression

Sodium Selenite results in increased expression of HNRNPK mRNA

NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997

G

homeo box B1

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of HOXB1 mRNA
Sodium Selenite results in decreased expression of HOXB1 mRNA

NCBI chr10:81,331,507...81,332,928
Ensembl chr10:81,331,507...81,332,836

G

homeo box B6

decreases expression

Sodium Selenite results in decreased expression of HOXB6 mRNA

NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449

G

homeo box D3

increases expression

Sodium Selenite results in increased expression of HOXD3 mRNA

NCBI chr 3:59,638,708...59,650,282
Ensembl chr 3:59,638,708...59,650,282

G

15-hydroxyprostaglandin dehydrogenase

multiple interactions
increases expression

N-TUTCA2 gene mutant form inhibits the reaction [Sodium Selenite results in increased expression of HPGD mRNA]; N-TUTCA2 gene mutant form inhibits the reaction [Sodium Selenite results in increased expression of HPGD protein]
Sodium Selenite results in increased expression of HPGD mRNA; Sodium Selenite results in increased expression of HPGD protein

NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228

G

hematopoietic prostaglandin D synthase

increases expression
multiple interactions

Sodium Selenite results in increased expression of HPGDS mRNA; Sodium Selenite results in increased expression of HPGDS protein
SEPHS2 protein affects the reaction [Sodium Selenite results in increased expression of HPGDS protein]

NCBI chr 4:94,368,426...94,397,931
Ensembl chr 4:94,373,342...94,397,883

G

hepsin

decreases expression

Sodium Selenite results in decreased expression of HPN mRNA

NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein]; [Sodium Selenite results in increased abundance of Selenium] which results in increased expression of HSD11B2 protein

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

heat shock transcription factor 1

increases expression

Sodium Selenite results in increased expression of HSF1 mRNA

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 alpha family class B member 1

increases expression

Sodium Selenite results in increased expression of HSP90AB1 mRNA

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein family A (Hsp70) member 2

decreases expression

Sodium Selenite results in decreased expression of HSPA2 mRNA

NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287

G

heat shock protein family A (Hsp70) member 5

increases expression

Sodium Selenite results in increased expression of HSPA5 protein

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family A (Hsp70) member 8

increases expression

Sodium Selenite results in increased expression of HSPA8 mRNA

NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259

G

heat shock protein family A (Hsp70) member 9

increases expression

Sodium Selenite results in increased expression of HSPA9 mRNA

NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292

G

heat shock protein family B (small) member 9

increases expression

Sodium Selenite results in increased expression of HSPB9 mRNA

NCBI chr10:85,641,284...85,641,929
Ensembl chr10:85,641,284...85,641,929

G

heat shock protein family D (Hsp60) member 1

increases expression

Sodium Selenite results in increased expression of HSPD1 mRNA

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

intercellular adhesion molecule 1

multiple interactions

Sodium Selenite inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Sodium Selenite inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inducible T-cell co-stimulator

increases expression

Sodium Selenite results in increased expression of ICOS mRNA

NCBI chr 9:62,368,075...62,406,900
Ensembl chr 9:62,383,832...62,405,672

G

alpha-L-iduronidase

decreases expression

Sodium Selenite results in decreased expression of IDUA mRNA

NCBI chr14:1,031,588...1,059,494
Ensembl chr14:1,032,171...1,046,522

G

immediate early response 3

increases expression

Sodium Selenite results in increased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

interferon alpha and beta receptor subunit 2

increases expression

Sodium Selenite results in increased expression of IFNAR2 mRNA

NCBI chr11:30,613,576...30,645,958
Ensembl chr11:30,613,767...30,668,124

G

interferon beta 1

multiple interactions

Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; Sodium Selenite inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]

NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523

G

interferon, epsilon

decreases expression

Sodium Selenite results in decreased expression of IFNE mRNA

NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256

G

interferon gamma

increases expression
multiple interactions
decreases expression

Sodium Selenite results in increased expression of IFNG protein
Sodium Selenite inhibits the reaction [Cadmium Chloride results in decreased expression of IFNG protein]
N-TUTCA2 gene mutant form inhibits the reaction [Sodium Selenite results in decreased expression of IFNG mRNA]; Sodium Selenite inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased activity of SP1 protein]; Sodium Selenite inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of SOD2 mRNA]; Sodium Selenite inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of UCP2 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]

PMID:15650415 PMID:18789669 PMID:24954678 PMID:25187657

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon-related developmental regulator 1

increases expression

Sodium Selenite results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

interferon-related developmental regulator 2

increases expression

Sodium Selenite results in increased expression of IFRD2 mRNA

NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194

G

intraflagellar transport 27

increases expression

Sodium Selenite results in increased expression of IFT27 mRNA

NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416

G

insulin-like growth factor 1

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of IGF1 mRNA
Sodium Selenite results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 2 mRNA binding protein 2

decreases expression

Sodium Selenite results in decreased expression of IGF2BP2 mRNA

NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377

G

insulin-like growth factor binding protein 5

multiple interactions

[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA

NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156

G

insulin-like growth factor binding protein 7

increases expression

Sodium Selenite results in increased expression of IGFBP7 mRNA

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

interleukin 10

multiple interactions
decreases expression

Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of IL10 protein]
Sodium Selenite results in decreased expression of IL10 protein

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 10 receptor subunit beta

decreases expression

Sodium Selenite results in decreased expression of IL10RB mRNA

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

interleukin 17 receptor A

increases expression

Sodium Selenite results in increased expression of IL17R mRNA

NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174

G

interleukin 18

multiple interactions

Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL18 mRNA]

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

multiple interactions
increases expression
decreases expression

IL1B protein promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein]; IL1B protein promotes the reaction [Sodium Selenite results in increased expression of GPX4 mRNA]
Sodium Selenite results in increased expression of IL1B protein
N-TUTCA2 gene mutant form promotes the reaction [Sodium Selenite deficiency results in increased expression of IL1B mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
Sodium Selenite results in decreased expression of IL1B mRNA
[Sodium Selenite co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]

PMID:10871427 PMID:14642406 PMID:18789669 PMID:25187657 PMID:37967787

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 22 receptor subunit alpha 2

decreases expression

Sodium Selenite results in decreased expression of IL22RA2 mRNA

NCBI chr 1:14,353,736...14,377,844
Ensembl chr 1:14,364,489...14,377,844

G

interleukin 23 subunit alpha

increases expression

Sodium Selenite results in increased expression of IL23A mRNA

NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923

G

interleukin 27

increases expression

Sodium Selenite results in increased expression of IL27 mRNA

NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582

G

interleukin 3 receptor subunit alpha

increases expression

Sodium Selenite results in increased expression of IL3RA mRNA

NCBI chr12:16,318,081...16,323,781
Ensembl chr12:16,318,081...16,323,484

G

interleukin 6

multiple interactions
increases expression

Sodium Selenite inhibits the reaction [IL6 protein results in increased activity of AR protein]; Sodium Selenite inhibits the reaction [IL6 protein results in increased expression of KLK3 protein]; Sodium Selenite inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]
Sodium Selenite results in increased expression of IL6 mRNA
[Sodium Selenite co-treated with Plant Extracts] inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]; Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of IL6 protein]; Sodium Selenite inhibits the reaction [sodium arsenite results in increased expression of IL6 protein]; Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]; zinc chloride inhibits the reaction [Sodium Selenite promotes the reaction [[lead chloride co-treated with Cadmium Chloride co-treated with Mercuric Chloride co-treated with sodium arsenite] results in increased expression of IL6 protein]]

PMID:16757516 PMID:17346688 PMID:18175754 PMID:24954678 PMID:26085057 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inositol monophosphatase 2

increases expression

Sodium Selenite results in increased expression of IMPA2 mRNA

NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641

G

inhibin subunit alpha

multiple interactions

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of INHA mRNA

NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248

G

inhibin subunit beta E

increases expression

Sodium Selenite results in increased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

insulin 1

multiple interactions

mitoquinone inhibits the reaction [Sodium Selenite inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; Sodium Selenite inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]
Sodium Selenite inhibits the reaction [SOD1 gene mutant form inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]

PMID:23795780 PMID:24140496 PMID:26522834

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions
decreases expression

INS protein inhibits the reaction [Sodium Selenite results in increased secretion of SELENOP protein]
Sodium Selenite results in decreased expression of INS2 mRNA
[Dexamethasone co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in decreased expression of RUNX2 protein; [Dexamethasone co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in decreased expression of SP7 protein; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of RUNX2 mRNA; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of RUNX2 protein; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of SMAD2 mRNA; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of SMAD3 mRNA; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of SOX9 mRNA; [Folic Acid co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in increased expression of SP7 protein; TGFB1 protein affects the reaction [[Dexamethasone co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in decreased expression of SP7 protein]; TGFB1 protein inhibits the reaction [[Dexamethasone co-treated with INS protein co-treated with TF protein co-treated with Sodium Selenite] results in decreased expression of RUNX2 protein]

PMID:18972406 PMID:23274088 PMID:32324263

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

IQ motif containing GTPase activating protein 2

increases expression

Sodium Selenite results in increased expression of IQGAP2 mRNA

NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279

G

interleukin-1 receptor-associated kinase 4

increases expression

Sodium Selenite results in increased expression of IRAK4 mRNA

NCBI chr 7:125,682,502...125,708,294
Ensembl chr 7:125,682,488...125,717,837

G

interferon regulatory factor 3

multiple interactions

Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased activity of IRF3 protein]; Sodium Selenite inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IRF3 protein]; Sodium Selenite inhibits the reaction [Poly I-C results in increased activity of IRF3 protein]; Sodium Selenite inhibits the reaction [TBK1 protein results in increased activity of IRF3 protein]; Sodium Selenite inhibits the reaction [TICAM1 protein results in increased activity of IRF3 protein]

NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935

G

insulin receptor substrate 1

multiple interactions

Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein]

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

iron-sulfur cluster assembly 2

increases expression

Sodium Selenite results in increased expression of ISCA2 mRNA

NCBI chr 6:104,418,509...104,420,019
Ensembl chr 6:104,418,454...104,420,045

G

iron-sulfur cluster assembly enzyme

increases expression

Sodium Selenite results in increased expression of ISCU mRNA

NCBI chr12:42,852,305...42,858,150
Ensembl chr12:42,852,305...42,858,150

G

itchy E3 ubiquitin protein ligase

decreases expression

Sodium Selenite results in decreased expression of ITCH mRNA

NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543

G

integrin subunit alpha 1

increases expression

Sodium Selenite results in increased expression of ITGA1 mRNA

NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238

G

integrin subunit alpha 5

increases expression

Sodium Selenite results in increased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

IL2-inducible T-cell kinase

decreases expression

Sodium Selenite results in decreased expression of ITK mRNA

NCBI chr10:30,753,344...30,814,685
Ensembl chr10:30,753,344...30,814,685

G

inosine triphosphatase

increases expression

Sodium Selenite results in increased expression of ITPA mRNA

NCBI chr 3:117,885,464...117,897,247
Ensembl chr 3:117,885,099...117,897,249

G

jumping translocation breakpoint

increases expression

Sodium Selenite results in increased expression of JTB mRNA

NCBI chr 2:175,685,392...175,689,609
Ensembl chr 2:175,684,993...175,690,108

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression
decreases activity
increases phosphorylation

[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of JUN mRNA; [Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in decreased expression of JUN protein; [Sodium Selenite results in increased expression of JUN protein] which results in decreased activity of AR protein; MAPK8 protein affects the reaction [Sodium Selenite results in decreased activity of JUN protein]
Buthionine Sulfoximine inhibits the reaction [Sodium Selenite results in increased expression of JUN mRNA]; Glutathione affects the reaction [Sodium Selenite results in increased expression of JUN mRNA]
Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]
Sodium Selenite results in increased phosphorylation of JUN protein

PMID:10644709 PMID:11769627 PMID:16944776 PMID:17346688 PMID:18449455 More...

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

lysine acetyltransferase 2B

decreases expression

Sodium Selenite results in decreased expression of KAT2B mRNA

NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064

G

kelch repeat and BTB domain containing 11

increases expression

Sodium Selenite results in increased expression of KBTBD11 mRNA

NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736

G

potassium voltage-gated channel subfamily A member 2

decreases expression

Sodium Selenite results in decreased expression of KCNA2 mRNA

NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400

G

potassium voltage-gated channel subfamily A member 5

decreases expression

Sodium Selenite results in decreased expression of KCNA5 mRNA

NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697

G

potassium voltage-gated channel subfamily A regulatory beta subunit 1

decreases expression

Sodium Selenite results in decreased expression of KCNAB1 mRNA

NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534

G

potassium voltage-gated channel subfamily H member 4

decreases expression

Sodium Selenite results in decreased expression of KCNH4 mRNA

NCBI chr10:85,668,332...85,688,166
Ensembl chr10:85,668,337...85,688,158

G

potassium inwardly-rectifying channel, subfamily J, member 10

increases expression

Sodium Selenite results in increased expression of KCNJ10 mRNA

NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461

G

potassium inwardly-rectifying channel, subfamily J, member 13

decreases expression

Sodium Selenite results in decreased expression of KCNJ13 mRNA

NCBI chr 9:88,063,003...88,071,112
Ensembl chr 9:88,063,003...88,071,112

G

potassium calcium-activated channel subfamily N member 4

increases expression

Sodium Selenite results in increased expression of KCNN4 mRNA

NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340

G

potassium voltage-gated channel, modifier subfamily S, member 2

decreases expression

Sodium Selenite results in decreased expression of KCNS2 mRNA

NCBI chr 7:66,022,352...66,028,422
Ensembl chr 7:66,022,352...66,028,422

G

potassium channel tetramerization domain containing 1

increases expression

Sodium Selenite results in increased expression of KCTD1 mRNA

NCBI chr18:6,122,390...6,316,434
Ensembl chr18:6,122,390...6,317,393

G

lysine demethylase 1B

decreases expression

Sodium Selenite results in decreased expression of KDM1B mRNA

NCBI chr17:17,602,961...17,643,865
Ensembl chr17:17,602,961...17,643,800

G

lysine demethylase 5A

decreases expression
increases expression

Sodium Selenite results in decreased expression of KDM5A mRNA
Sodium Selenite results in increased expression of KDM5A mRNA

PMID:16705456 PMID:18175754

NCBI chr 4:153,565,909...153,643,912
Ensembl chr 4:153,565,846...153,642,422

G

Kelch-like ECH-associated protein 1

multiple interactions

Sodium Selenite inhibits the reaction [Sodium Fluoride results in decreased expression of KEAP1 mRNA]

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

alpha-ketoglutarate dehydrogenase subunit 4

increases expression

Sodium Selenite results in increased expression of KGD4 mRNA

NCBI chr 2:31,870,549...31,878,335
Ensembl chr 2:31,870,551...31,880,730

G

KH RNA binding domain containing, signal transduction associated 1

increases expression

Sodium Selenite results in increased expression of KHDRBS1 mRNA

NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180

G

KH-type splicing regulatory protein

increases expression

Sodium Selenite results in increased expression of KHSRP mRNA

NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451

G

kinesin family member 14

decreases expression

Sodium Selenite results in decreased expression of KIF14 mRNA

NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164

G

kinesin family member 4A

decreases expression

Sodium Selenite results in decreased expression of KIF4A mRNA

NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139

G

KLF transcription factor 7

decreases expression

Sodium Selenite results in decreased expression of KLF7 mRNA

NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261

G

kelch-like family member 7

decreases expression

Sodium Selenite results in decreased expression of KLHL7 mRNA

NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541

G

kallikrein 1-related peptidase C10

multiple interactions
decreases secretion
decreases expression

Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Sodium Selenite results in decreased expression of KLK3 protein]; Sodium Selenite inhibits the reaction [IL6 protein results in increased expression of KLK3 protein]; Sodium Selenite inhibits the reaction [Metribolone results in increased expression of KLK3 protein]
Sodium Selenite results in decreased secretion of KLK3 protein
Sodium Selenite results in decreased expression of KLK3 mRNA

PMID:16928829 PMID:17346688 PMID:18760546

NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052

G

kinetochore scaffold 1

decreases expression

Sodium Selenite results in decreased expression of KNL1 mRNA

NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915

G

keratin 35

increases expression

Sodium Selenite results in increased expression of KRT35 mRNA

NCBI chr10:85,026,171...85,029,568
Ensembl chr10:85,026,171...85,029,568

G

keratin 72

increases expression

Sodium Selenite results in increased expression of KRT72 mRNA

NCBI chr 7:132,910,379...132,920,844
Ensembl chr 7:132,910,613...132,920,783

G

kinectin 1

increases expression

Sodium Selenite results in increased expression of KTN1 mRNA

NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578

G

laminin subunit alpha 2

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of LAMA2 mRNA
Sodium Selenite results in decreased expression of LAMA2 mRNA

NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530

G

laminin subunit alpha 4

decreases expression

Sodium Selenite results in decreased expression of LAMA4 mRNA

NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347

G

laminin subunit gamma 1

decreases expression

Sodium Selenite results in decreased expression of LAMC1 mRNA

NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492

G

lecithin cholesterol acyltransferase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in decreased expression of LCAT mRNA]

NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231

G

late cornified envelope 1F

decreases expression

Sodium Selenite results in decreased expression of LCE1F mRNA

NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372

G

leucine carboxyl methyltransferase 1

increases expression

Sodium Selenite results in increased expression of LCMT1 mRNA

NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112

G

leucine carboxyl methyltransferase 2

decreases expression

Sodium Selenite results in decreased expression of LCMT2 mRNA

NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084

G

lactate dehydrogenase A

increases expression

Sodium Selenite results in increased expression of LDHA mRNA

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

lactate dehydrogenase B

increases expression

Sodium Selenite results in increased expression of LDHB mRNA

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

low density lipoprotein receptor

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

low density lipoprotein receptor class A domain containing 3

increases expression

Sodium Selenite results in increased expression of LDLRAD3 mRNA

NCBI chr 3:88,239,529...88,481,340
Ensembl chr 3:88,239,622...88,481,267

G

LDOC1, regulator of NFKB signaling

decreases expression

Sodium Selenite results in decreased expression of LDOC1 mRNA

NCBI chr X:139,965,509...140,074,355
Ensembl chr X:139,965,509...140,074,355

G

leukocyte receptor cluster member 1

increases expression

Sodium Selenite results in increased expression of LENG1 mRNA

NCBI chr 1:65,551,983...65,556,915
Ensembl chr 1:65,551,983...65,556,915

G

leptin

decreases expression

Sodium Selenite results in decreased expression of LEP mRNA

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

G

galectin 4

increases expression

Sodium Selenite results in increased expression of LGALS4 mRNA

NCBI chr 1:84,124,766...84,132,481
Ensembl chr 1:84,124,764...84,132,481

G

luteinizing hormone subunit beta

multiple interactions

Sodium Selenite inhibits the reaction [sodium arsenite results in decreased expression of LHB protein]

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM homeobox 1

increases expression

Sodium Selenite results in increased expression of LHX1 mRNA

NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617

G

LIM homeobox 5

multiple interactions
decreases expression

[ptaquiloside co-treated with Sodium Selenite] results in decreased expression of LHX5 mRNA
Sodium Selenite results in decreased expression of LHX5 mRNA

NCBI chr12:36,126,186...36,134,625
Ensembl chr12:36,126,186...36,134,625

G

leukocyte immunoglobulin like receptor A5

decreases expression

Sodium Selenite results in decreased expression of LILRA5 mRNA

NCBI chr 1:69,973,292...69,978,750
Ensembl chr 1:69,973,292...70,001,718

G

LIM domain containing 2

increases expression

Sodium Selenite results in increased expression of LIMD2 mRNA

NCBI chr10:91,090,279...91,092,772
Ensembl chr10:91,090,280...91,092,775

G

lipase E, hormone sensitive type

increases phosphorylation

Sodium Selenite results in increased phosphorylation of LIPE protein

NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310

G

LLP homolog, long-term synaptic facilitation factor

increases expression

Sodium Selenite results in increased expression of LLPH mRNA

NCBI chr 7:55,735,317...55,740,341
Ensembl chr 7:55,735,400...55,740,339

G

lemur tyrosine kinase 3

decreases expression

Sodium Selenite results in decreased expression of LMTK3 mRNA

NCBI chr 1:96,261,058...96,280,362
Ensembl chr 1:96,260,977...96,280,672

G

small nucleolar RNA SNORA71

increases expression

Sodium Selenite results in increased expression of SNORA71D mRNA

NCBI chr 1:232,131,169...232,131,300
Ensembl chr 1:232,131,169...232,131,300

G

lysyl oxidase-like 2

decreases expression

Sodium Selenite results in decreased expression of LOXL2 mRNA

NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067

G

lipin 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

LIM domain containing preferred translocation partner in lipoma

decreases expression

Sodium Selenite results in decreased expression of LPP mRNA

NCBI chr11:75,787,326...76,426,646
Ensembl chr11:75,797,078...76,422,597

G

leupaxin

increases expression

Sodium Selenite results in increased expression of LPXN mRNA

NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084

G

leucine rich repeat and fibronectin type III domain containing 3

increases expression

Sodium Selenite results in increased expression of LRFN3 mRNA

NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725

G

LDL receptor related protein 10

increases expression

Sodium Selenite results in increased expression of LRP10 mRNA

NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505

G

LDL receptor related protein 12

decreases expression

Sodium Selenite results in decreased expression of LRP12 mRNA

NCBI chr 7:70,941,068...71,012,409
Ensembl chr 7:70,941,068...71,012,441

G

leucine rich repeat containing 45

increases expression

Sodium Selenite results in increased expression of LRRC45 mRNA

NCBI chr10:105,994,468...106,002,425
Ensembl chr10:105,993,087...106,002,424

G

leucine rich repeat containing 47

increases expression

Sodium Selenite results in increased expression of LRRC47 mRNA

NCBI chr 5:164,570,539...164,580,174
Ensembl chr 5:164,570,435...164,580,174

G

leucine rich repeat and sterile alpha motif containing 1

decreases expression

Sodium Selenite results in decreased expression of LRSAM1 mRNA

NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154

G

LSM10, U7 small nuclear RNA associated

increases expression

Sodium Selenite results in increased expression of LSM10 mRNA

NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505

G

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression

Sodium Selenite results in increased expression of LSM6 mRNA

NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484

G

LSM8 homolog, U6 small nuclear RNA associated

increases expression

Sodium Selenite results in increased expression of LSM8 mRNA

NCBI chr 4:47,306,259...47,312,125
Ensembl chr 4:47,306,295...47,314,293

G

lymphotoxin beta

decreases expression

Sodium Selenite results in decreased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

latent transforming growth factor beta binding protein 1

decreases expression

Sodium Selenite results in decreased expression of LTBP1 mRNA

NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349

G

lactotransferrin

increases expression

Sodium Selenite results in increased expression of LTF mRNA

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

G

LTV1 ribosome biogenesis factor

increases expression

Sodium Selenite results in increased expression of LTV1 mRNA

NCBI chr 1:7,565,673...7,578,398
Ensembl chr 1:7,565,669...7,578,563

G

lymphocyte antigen 6 family member G6C

increases expression

Sodium Selenite results in increased expression of LY6G6C mRNA

NCBI chr20:3,753,632...3,757,205
Ensembl chr20:3,753,632...3,758,867

G

lymphocyte antigen 86

increases expression

Sodium Selenite results in increased expression of LY86 mRNA

NCBI chr17:27,415,807...27,499,695
Ensembl chr17:27,415,830...27,487,260

G

macroH2A.1 histone

increases expression

Sodium Selenite results in increased expression of MACROH2A1 mRNA

NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072

G

MAF bZIP transcription factor G

decreases expression

Sodium Selenite results in decreased expression of MAFG mRNA

NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026

G

MAGE family member D1

increases expression

Sodium Selenite results in increased expression of MAGED1 mRNA

NCBI chr X:59,422,715...59,429,381
Ensembl chr X:59,422,717...59,429,364

G

mastermind-like transcriptional coactivator 3

decreases expression

Sodium Selenite results in decreased expression of MAML3 mRNA

NCBI chr 2:135,720,431...136,137,829
Ensembl chr 2:135,721,021...136,137,814

G

mannosidase, alpha, class 1C, member 1

increases expression

Sodium Selenite results in increased expression of MAN1C1 mRNA

NCBI chr 5:146,774,282...146,913,257
Ensembl chr 5:146,775,842...146,913,421

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions

[Sodium Selenite co-treated with (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane] results in increased expression of MAP1LC3B protein modified form
Sodium Selenite inhibits the reaction [citreoviridin results in increased expression of MAP1LC3B protein modified form]

PMID:28757135 PMID:31419397

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen activated protein kinase kinase 1

decreases expression

Sodium Selenite results in decreased expression of MAP2K1 mRNA

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

increases expression

Sodium Selenite results in increased expression of MAP2K2 mRNA

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase 4

multiple interactions

Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein]

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen-activated protein kinase kinase 6

decreases expression
increases expression

Sodium Selenite results in decreased expression of MAP2K6 mRNA
Sodium Selenite results in increased expression of MAP2K6 mRNA

PMID:16705456 PMID:18175754

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

G

mitogen-activated protein kinase kinase kinase 14

decreases expression

Sodium Selenite results in decreased expression of MAP3K14 mRNA

NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523

G

mitogen-activated protein kinase kinase kinase 5

multiple interactions

Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein]

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen activated protein kinase kinase kinase 7

increases expression

Sodium Selenite results in increased expression of MAP3K7 mRNA

NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597

G

mitogen-activated protein kinase kinase kinase kinase 5

decreases expression

Sodium Selenite results in decreased expression of MAP4K5 mRNA

NCBI chr 6:88,284,087...88,377,118
Ensembl chr 6:88,284,094...88,376,799

G

MAP7 domain containing 3

increases expression

Sodium Selenite results in increased expression of MAP7D3 mRNA

NCBI chr X:134,619,227...134,647,525
Ensembl chr X:134,619,227...134,685,841

G

mitogen activated protein kinase 1

increases phosphorylation
decreases phosphorylation
multiple interactions

Sodium Selenite results in increased phosphorylation of MAPK1 protein
Sodium Selenite results in decreased phosphorylation of MAPK1 protein
[Sodium Selenite co-treated with coenzyme Q10] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]