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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:agonist
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Accession:CHEBI:48705 term browser browse the term
Definition:Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
Synonyms:related_synonym: agonista;   agoniste;   agonists


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      CHEBI ontology 19911
        role 19854
          biological role 19852
            pharmacological role 19106
              agonist 18622
                5-hydroxytryptamine 2A receptor agonist + 12
                5-hydroxytryptamine 2B receptor agonist + 12
                5-hydroxytryptamine 2C receptor agonist + 12
                AMCR277A 0
                AMPA receptor agonist + 2
                G-1 0
                G-protein-coupled receptor agonist + 83
                IP3 receptor agonist + 0
                K-ATP channel agonist + 136
                LRH-1 agonist + 0
                MAIT cell agonist + 0
                NOD1 agonist + 0
                P2Y2 receptor agonist + 0
                PPARalpha agonist + 3147
                PPARbeta/delta agonist + 65
                PPARgamma agonist + 763
                SMO receptor agonist + 940
                TRPA1 channel agonist + 41
                TRPV1 agonist + 522
                TRPV4 agonist + 0
                Toll-like receptor 2 agonist + 2
                abscisic acid receptor agonist + 1
                adenosine receptor agonist + 71
                adenylate cyclase agonist + 345
                androstane receptor agonist + 3824
                aryl hydrocarbon receptor agonist + 1989
                beta-alanine + 60
                bradykinin receptor agonist + 48
                bucladesine 311
                cannabinoid receptor agonist + 1528
                capsaicin receptor agonist + 7
                elastin-laminin receptor agonist + 26
                erythropeotin receptor agonist + 0
                estrogen receptor agonist + 1196
                farnesoid X receptor agonist + 291
                formyl peptide receptor agonist + 0
                glucagon-like peptide-2 receptor agonist + 0
                glucocorticoid receptor agonist + 20
                glycine receptor agonist + 425
                guanylate cyclase 2C agonist + 0
                hormone + 18507
                hormone agonist + 2786
                insulin-sensitizing drug + 976
                kisspeptin receptor agonist + 0
                liver X receptor agonist + 1
                lysophosphatidic acid receptor 3 agonist + 0
                melatonin receptor agonist + 0
                metabotropic glutamate receptor agonist + 9
                neurokinin-1 receptor agonist + 0
                neuropeptide FF receptor agonist + 0
                neuropeptide Y2 receptor agonist + 0
                odorant receptor agonist + 7
                opioid receptor agonist + 773
                piezo1 agonist + 1
                platelet-activating factor receptor agonist + 0
                pregnane X receptor agonist + 404
                prostacyclin receptor agonist + 0
                prostaglandin receptor agonist + 19
                protein kinase agonist + 9210
                retinoic acid receptor agonist + 9978
                retinoid X receptor agonist + 9955
                sphingosine-1-phosphate receptor agonist + 109
                thrombopoietin receptor agonist + 1
                thromboxane A2 agonist + 2
                tropomyosin-related kinase B receptor agonist + 226
                vitamin D receptor agonist + 0
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