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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-valerolactone
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Accession:CHEBI:48569 term browser browse the term
Definition:A butan-4-olide that is dihydrofuran-2(3H)-one substituted by a methyl group at position 5. It has been found in the urine samples of humans exposed to n-hexane.
Synonyms:exact_synonym: 5-methyldihydrofuran-2(3H)-one
 related_synonym: 4-Hydroxypentanoic acid lactone;   4-Hydroxyvaleric acid lactone;   4-Methyl-4-hydroxybutanoic acid lactone;   4-Methyl-gamma-butyrolactone;   4-Pentanolide;   4-Valerolactone;   Formula=C5H8O2;   InChI=1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3;   InChIKey=GAEKPEKOJKCEMS-UHFFFAOYSA-N;   SMILES=CC1CCC(=O)O1;   dihydro-5-methyl-2(3H)-furanone;   gamma-Pentalactone;   gamma-Pentanolactone
 xref: CAS:108-29-2;   HMDB:HMDB0033840
 xref_mesh: MESH:C037556
 xref: PMID:23486087;   PMID:7470400;   Patent:CN101633649;   Reaxys:80420;   Wikipedia:Gamma-Valerolactone


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gamma-valerolactone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO gamma-valerolactone results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        food additive 16831
          flavouring agent 4866
            gamma-valerolactone 1
              (R)-gamma-valerolactone 0
              (S)-gamma-valerolactone 0
              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  ester 17455
                                    carboxylic ester 16741
                                      lactone 13297
                                        gamma-lactone 6854
                                          butan-4-olide 308
                                            gamma-valerolactone 1
                                              (R)-gamma-valerolactone 0
                                              (S)-gamma-valerolactone 0
                                              5-(3',4',5'-trihydroxyphenyl)-gamma-valerolactone 0
                                              5-(3',4'-dihydroxyphenyl)-gamma-valerolactone 3'-O-sulfate 0
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