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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-adrenergic drug
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Accession:CHEBI:48539 term browser browse the term
Definition:Any drug that acts on an α-adrenergic receptor.
Synonyms:related_synonym: alpha-adrenergic drugs


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(R)-adrenaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases export 		EXP [Epinephrine co-treated with [verlukast results in decreased activity of ABCC1 protein]] results in increased abundance of Glutathione Disulfide; [verlukast results in decreased activity of ABCC1 protein] which promotes the reaction and affects the abundance of Epinephrine metabolite
ABCC1 protein results in increased export of Epinephrine metabolite 		CTD PMID:19053318 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Aco2 aconitase 2 increases expression EXP Epinephrine results in increased expression of ACO2 protein CTD PMID:19464573 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892 		JBrowse link
G Actn1 actinin, alpha 1 increases expression EXP Epinephrine results in increased expression of ACTN1 protein CTD PMID:19464573 NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression 		EXP Sildenafil Citrate inhibits the reaction [Epinephrine results in decreased expression of ADIPOQ protein]; Tadalafil inhibits the reaction [Epinephrine results in decreased expression of ADIPOQ protein] CTD PMID:29233027 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
increases activity
affects binding 		EXP
ISO 		[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Epinephrine binds to and results in increased activity of ADRA1A protein
Epinephrine results in increased activity of ADRA1A protein
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Epinephrine binds to and results in increased activity of ADRA1A protein; Epinephrine inhibits the reaction [ADRA1A protein binds to Prazosin]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
Epinephrine binds to ADRA1A protein 		CTD PMID:8183249 PMID:15306222 PMID:15672411 PMID:20030735 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
increases activity 		ISO [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Epinephrine binds to and results in increased activity of ADRA1B protein; Epinephrine inhibits the reaction [ADRA1B protein binds to Prazosin]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 PMID:20030735 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding
increases activity
multiple interactions 		ISO Epinephrine binds to ADRA1D protein
Epinephrine results in increased activity of ADRA1D protein
[Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; Carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Epinephrine binds to and results in increased activity of ADRA1D protein; Epinephrine inhibits the reaction [ADRA1D protein binds to Prazosin]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] 		CTD PMID:8183249 PMID:15306222 PMID:20030735 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases activity
multiple interactions 		EXP
ISO 		Epinephrine results in increased activity of ADRA2A protein
Epinephrine promotes the reaction [GNB2 protein binds to ADRA2A protein]; Epinephrine promotes the reaction [GNB4 protein binds to ADRA2A protein]; Epinephrine promotes the reaction [GNG12 protein binds to ADRA2A protein]; Epinephrine promotes the reaction [GNG2 protein binds to ADRA2A protein]; Epinephrine promotes the reaction [GNG3 protein binds to ADRA2A protein]; Epinephrine promotes the reaction [GNG4 protein binds to ADRA2A protein]
[Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; ADRA2A promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; Epinephrine binds to and results in increased activity of ADRA2A protein; Epinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan] 		CTD PMID:17341653 PMID:17680988 PMID:20030735 PMID:30737458 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; ADRA2B promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; Epinephrine binds to and results in increased activity of ADRA2B protein; Epinephrine inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] CTD PMID:17680988 PMID:20030735 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; ADRA2C promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; Epinephrine binds to and results in increased activity of ADRA2C protein; Epinephrine inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan] CTD PMID:17680988 PMID:20030735 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
increases activity 		ISO
EXP 		[CGP 20712A binds to and results in decreased activity of ADRB1 protein] which results in decreased activity of Epinephrine
Epinephrine results in increased activity of ADRB1 protein
Epinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]
[Epinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; columbamine inhibits the reaction [Epinephrine results in increased activity of ADRB1 protein]; epiberberine affects the reaction [Epinephrine results in increased activity of ADRB1 protein]; Epinephrine binds to and results in increased activity of ADRB1 protein; Epinephrine inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Epinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Harmaline affects the reaction [Epinephrine results in increased activity of ADRB1 protein]; Harmine affects the reaction [Epinephrine results in increased activity of ADRB1 protein]; Nebivolol inhibits the reaction [Epinephrine results in increased activity of ADRB1 protein]; nuciferine affects the reaction [Epinephrine results in increased activity of ADRB1 protein]; palmatine inhibits the reaction [Epinephrine results in increased activity of ADRB1 protein]; Propranolol inhibits the reaction [Epinephrine results in increased activity of ADRB1 protein] 		CTD PMID:8096834 PMID:12010770 PMID:14730417 PMID:30155694 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
affects response to substance
increases activity 		ISO
EXP 		3,4-dihydroxyphenyllactic acid inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; [Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; anhydroicaritin inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Atenolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Atenolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; Carvedilol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; columbamine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Emodin inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; epiberberine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Epinephrine binds to and results in increased activity of ADRB2 protein; Epinephrine inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Epinephrine promotes the reaction [GRK2 protein results in increased phosphorylation of ADRB2 protein]; Epinephrine promotes the reaction [GRK5 protein results in increased phosphorylation of ADRB2 protein]; Epinephrine results in increased phosphorylation of and results in increased localization of ADRB2 protein; Harmaline inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Harmine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; ICI 118551 inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; ICI 118551 inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; liquiritin inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; nuciferine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; palmatine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [[Epinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP]; Propranolol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; Propranolol inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; protopine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; Synephrine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]; tetrahydrocolumbamine inhibits the reaction [Epinephrine results in increased activity of ADRB2 protein]
[Epinephrine results in increased activity of ADRB2 protein] which results in increased secretion of Histamine
ADRB2 affects the susceptibility to Epinephrine 		CTD PMID:1389726 PMID:11164953 PMID:12920204 PMID:14722251 PMID:14730417 More... NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP
ISO 		Epinephrine binds to and results in increased activity of ADRB3 protein
[Epinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Epinephrine binds to and results in increased activity of ADRB3 protein; Epinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein] 		CTD PMID:1682311 PMID:7815362 PMID:14730417 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Ak2 adenylate kinase 2 decreases expression
multiple interactions 		EXP Epinephrine results in decreased expression of AK2 protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of AK2 protein 		CTD PMID:19464573 NCBI chr 5:146,609,469...146,649,008
Ensembl chr 5:146,630,445...146,650,610 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [Epinephrine co-treated with INS protein] results in increased phosphorylation of AKT1 protein CTD PMID:32305330 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions
increases activity 		EXP Cycloheximide inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Timolol inhibits the reaction [Epinephrine results in increased activity of AOC1 protein] CTD PMID:2860926 NCBI chr 4:79,143,126...79,162,705
Ensembl chr 4:79,143,126...79,162,704 		JBrowse link
G Aqp7 aquaporin 7 affects localization
multiple interactions
increases expression 		ISO Epinephrine affects the localization of AQP7 protein
INS1 inhibits the reaction [Epinephrine results in increased expression of AQP7 mRNA] 		CTD PMID:10777495 NCBI chr 5:60,968,495...60,982,618
Ensembl chr 5:60,967,558...60,982,618 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression EXP Epinephrine results in increased expression of ATP5F1A protein CTD PMID:19464573 NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO Epinephrine results in increased expression of BCL2 protein CTD PMID:36423730 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bmp2 bone morphogenetic protein 2 decreases expression ISO Epinephrine results in decreased expression of BMP2 mRNA; Epinephrine results in decreased expression of BMP2 protein CTD PMID:31520687 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G C1qbp complement C1q binding protein multiple interactions
increases expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of C1QBP protein
Epinephrine results in increased expression of C1QBP protein 		CTD PMID:19464573 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases abundance EXP CALCA protein results in increased abundance of Epinephrine CTD PMID:8058111 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Caly calcyon neuron-specific vesicular protein decreases secretion ISO CALY protein results in decreased secretion of Epinephrine CTD PMID:30753204 NCBI chr 1:204,292,317...204,303,506
Ensembl chr 1:204,292,318...204,303,196 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Epinephrine results in increased expression of CA2 mRNA CTD PMID:12729923 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity 		ISO
EXP 		Atenolol inhibits the reaction [Epinephrine results in increased activity of CASP3 protein]; carvedilol inhibits the reaction [Epinephrine results in increased activity of CASP3 protein]
Epinephrine results in increased expression of CASP3 protein
Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] results in increased activity of CASP3 protein]; Sildenafil Citrate inhibits the reaction [Epinephrine results in increased expression of CASP3 protein]; Tadalafil inhibits the reaction [Epinephrine results in increased expression of CASP3 protein]; Vardenafil Dihydrochloride inhibits the reaction [Epinephrine results in increased expression of CASP3 protein] 		CTD PMID:10728402 PMID:19135123 PMID:29233027 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase decreases response to substance ISO CAT results in decreased susceptibility to Epinephrine CTD PMID:25172298 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Epinephrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 mRNA]; Epinephrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]; Propranolol inhibits the reaction [Epinephrine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL3 protein]]
Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA]; Epinephrine inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]; Epinephrine inhibits the reaction [Thioglycolates results in increased secretion of CCL3 protein] 		CTD PMID:9863660 PMID:12538206 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression 		EXP
ISO 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; 2-methoxyidazoxan inhibits the reaction [Epinephrine results in increased expression of CCND1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]
Epinephrine results in increased expression of CCND1 mRNA; Epinephrine results in increased expression of CCND1 protein
ADRA2A promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased expression of CCND1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased expression of CCND1 protein] 		CTD PMID:17680988 PMID:26964897 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Epinephrine results in decreased expression of CEBPB protein CTD PMID:31520687 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO [methyllycaconitine binds to and results in decreased activity of CHRNA7 protein] inhibits the reaction [Nicotine results in increased abundance of Epinephrine] CTD PMID:17498763 NCBI chr 1:126,123,425...126,249,181
Ensembl chr 1:126,123,425...126,446,858 		JBrowse link
G Comt catechol-O-methyltransferase increases methylation
multiple interactions 		ISO
EXP 		COMT protein results in increased methylation of Epinephrine
[COMT protein results in increased methylation of Epinephrine] which results in increased abundance of Metanephrine; tolcapone inhibits the reaction [[COMT protein results in increased methylation of Epinephrine] which results in increased abundance of Metanephrine]
[tolcapone results in decreased activity of COMT protein] which results in increased abundance of Epinephrine 		CTD PMID:8821542 PMID:10064789 PMID:11160877 PMID:11248589 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases phosphorylation 		ISO
EXP 		ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; Dietary Fats promotes the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; Epinephrine promotes the reaction [Dietary Fats results in increased phosphorylation of CREB1 protein]; Ketoconazole inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased phosphorylation of CREB1 protein] 		CTD PMID:17680988 PMID:22496244 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases abundance 		EXP corticotropin releasing hormone (9-41) inhibits the reaction [CRH protein affects the abundance of Epinephrine]
CRH results in increased abundance of Epinephrine 		CTD PMID:1320258 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Csk C-terminal Src kinase multiple interactions ISO CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]; Isoproterenol inhibits the reaction [CSK protein promotes the reaction [Epinephrine results in increased abundance of Cyclic AMP]] CTD PMID:1699227 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:66,925,651...66,930,274 		JBrowse link
G Ctnnb1 catenin beta 1 increases phosphorylation
multiple interactions 		EXP Epinephrine results in increased phosphorylation of CTNNB1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein] 		CTD PMID:26964897 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsk cathepsin K increases expression ISO Epinephrine results in increased expression of CTSK mRNA CTD PMID:12729923 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of CYCS protein
Epinephrine results in increased expression of CYCS protein 		CTD PMID:19464573 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Dbh dopamine beta-hydroxylase affects abundance ISO DBH gene polymorphism affects the abundance of Epinephrine CTD PMID:16163519 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Des desmin multiple interactions
decreases expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DES protein
Epinephrine results in decreased expression of DES protein 		CTD PMID:19464573 NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DLAT protein CTD PMID:19464573 NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:59,868,214...59,900,818
Ensembl chr 1:59,868,214...59,900,818 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of ECHS1 protein CTD PMID:19464573 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506 		JBrowse link
G Epha4 Eph receptor A4 increases phosphorylation ISO Epinephrine results in increased phosphorylation of EPHA4 protein CTD PMID:22273509 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of ETFB protein CTD PMID:19464573 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659 		JBrowse link
G Fabp3 fatty acid binding protein 3 affects expression
multiple interactions 		EXP Epinephrine affects the expression of FABP3 protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of FABP3 protein 		CTD PMID:19464573 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression 		ISO Atenolol inhibits the reaction [Epinephrine results in increased expression of FAS protein]; carvedilol inhibits the reaction [Epinephrine results in increased expression of FAS protein] CTD PMID:10728402 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions
increases expression 		ISO Atenolol inhibits the reaction [Epinephrine results in increased expression of FASLG protein]; carvedilol inhibits the reaction [Epinephrine results in increased expression of FASLG protein] CTD PMID:10728402 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fh fumarate hydratase increases expression EXP Epinephrine results in increased expression of FH protein CTD PMID:19464573 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627 		JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO Epinephrine results in decreased expression of FOXO1 protein CTD PMID:31520687 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Gnb2 G protein subunit beta 2 multiple interactions ISO Epinephrine promotes the reaction [GNB2 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr12:24,795,505...24,800,796
Ensembl chr12:24,795,827...24,800,796 		JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO Epinephrine promotes the reaction [GNB4 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr 2:117,289,112...117,329,050
Ensembl chr 2:117,293,284...117,328,945 		JBrowse link
G Gng12 G protein subunit gamma 12 multiple interactions ISO Epinephrine promotes the reaction [GNG12 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr 4:97,340,830...97,464,422
Ensembl chr 4:97,340,472...97,464,476 		JBrowse link
G Gng2 G protein subunit gamma 2 multiple interactions ISO Epinephrine promotes the reaction [GNG2 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr15:4,365,222...4,466,060
Ensembl chr15:4,365,135...4,466,059 		JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions ISO Epinephrine promotes the reaction [GNG3 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr 1:215,160,952...215,162,718
Ensembl chr 1:215,160,952...215,162,718 		JBrowse link
G Gng4 G protein subunit gamma 4 multiple interactions ISO Epinephrine promotes the reaction [GNG4 protein binds to ADRA2A protein] CTD PMID:30737458 NCBI chr17:93,432,791...93,481,709
Ensembl chr17:93,433,195...93,481,709 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO Epinephrine promotes the reaction [GRK2 protein results in increased phosphorylation of ADRB2 protein] CTD PMID:14722251 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 multiple interactions ISO Epinephrine promotes the reaction [GRK5 protein results in increased phosphorylation of ADRB2 protein] CTD PMID:14722251 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HADH protein CTD PMID:19464573 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Epinephrine results in increased expression of HIF1A protein CTD PMID:36423730 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Epinephrine results in increased expression of HK2 protein CTD PMID:36423730 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275 		JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions
affects localization 		EXP Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] affects the localization of HSF1 protein]
Epinephrine affects the localization of HSF1 protein 		CTD PMID:19135123 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSP90AB1 protein CTD PMID:19464573 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of HSPA5 protein CTD PMID:19464573 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Epinephrine results in increased expression of HSPA8 protein CTD PMID:19464573 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSPA9 protein CTD PMID:19464573 NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398 		JBrowse link
G Hspb6 heat shock protein family B (small) member 6 decreases expression
multiple interactions 		EXP Epinephrine results in decreased expression of HSPB6 protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSPB6 protein 		CTD PMID:19464573 NCBI chr 1:94,934,372...94,936,516
Ensembl chr 1:94,933,543...94,936,512 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression
multiple interactions 		EXP Epinephrine results in decreased expression of IDH2 protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of IDH2 protein 		CTD PMID:19464573 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO Epinephrine promotes the reaction [Lipopolysaccharides results in increased expression of IL10 protein] CTD PMID:10588509 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:10588509 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions 		EXP
ISO 		Epinephrine results in decreased expression of IL6 mRNA
Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] 		CTD PMID:10588509 PMID:12423672 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions ISO
EXP 		INS1 inhibits the reaction [Epinephrine results in increased expression of AQP7 mRNA]
cilostamide inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]]; Cytochalasin B inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]]; hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]]; INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]; Wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Epinephrine results in increased transport of Fatty Acids, Nonesterified]] 		CTD PMID:10777495 PMID:15172182 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression 		ISO [Epinephrine co-treated with INS protein] results in increased phosphorylation of AKT1 protein; Butoxamine inhibits the reaction [Epinephrine results in decreased expression of INS protein]; Pentolinium Tartrate inhibits the reaction [Epinephrine results in decreased secretion of INS protein]; Propranolol inhibits the reaction [Epinephrine results in decreased expression of INS protein] CTD PMID:1218171 PMID:6018752 PMID:6314140 PMID:32305330 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Epinephrine] CTD PMID:16214444 NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:48,253,412...48,354,509 		JBrowse link
G Itgav integrin subunit alpha V increases expression ISO Epinephrine results in increased expression of ITGAV mRNA CTD PMID:12729923 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:89,245,095...89,333,511 		JBrowse link
G Itgb1 integrin subunit beta 1 increases response to substance EXP ITGB1 results in increased susceptibility to Epinephrine CTD PMID:14984413 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269 		JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases expression
affects localization
increases activity 		ISO
EXP 		Theophylline inhibits the reaction [Epinephrine results in increased activity of LIPE protein]
Epinephrine results in increased expression of LIPE mRNA
Epinephrine affects the localization of LIPE protein 		CTD PMID:7155675 PMID:10777495 PMID:11160373 NCBI chr 1:90,093,433...90,112,117
Ensembl chr 1:90,093,433...90,112,117 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases activity
affects activity 		ISO
EXP 		ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]; Epinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Epinephrine results in increased phosphorylation of MAPK1 protein]
Epinephrine deficiency results in increased activity of MAPK1 protein
Epinephrine affects the activity of MAPK1 protein 		CTD PMID:11093795 PMID:15292328 PMID:17680988 PMID:22496244 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases activity
affects activity 		ISO
EXP 		ADRA2A promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; ADRA2B promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; ADRA2C promotes the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]; Epinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Epinephrine results in increased phosphorylation of MAPK3 protein]
Epinephrine deficiency results in increased activity of MAPK3 protein
Epinephrine affects the activity of MAPK3 protein 		CTD PMID:11093795 PMID:15292328 PMID:17680988 PMID:22496244 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Meis1 Meis homeobox 1 decreases expression ISO Epinephrine results in decreased expression of MEIS1 protein CTD PMID:31520687 NCBI chr14:97,356,949...97,499,646
Ensembl chr14:97,322,748...97,495,083 		JBrowse link
G Myl2 myosin light chain 2 multiple interactions
affects expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] affects the expression of MYL2 protein
Epinephrine affects the expression of MYL2 protein 		CTD PMID:19464573 NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Epinephrine affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions EXP Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] results in increased activity of [RELA protein binds to NFKB1 protein]]; Epinephrine results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:19135123 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression 		ISO
EXP 		Atenolol inhibits the reaction [Epinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Atenolol inhibits the reaction [Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Epinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Prazosin inhibits the reaction [Epinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Prazosin inhibits the reaction [Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
Epinephrine results in increased expression of NOS2 mRNA 		CTD PMID:16925470 PMID:19439816 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Epinephrine results in increased expression of NTF3 mRNA; Epinephrine results in increased expression of NTF3 protein CTD PMID:19854260 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G P2rx7 purinergic receptor P2X 7 decreases activity ISO Epinephrine results in decreased activity of P2RX7 protein CTD PMID:15459114 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G P2ry12 purinergic receptor P2Y12 multiple interactions ISO Epinephrine inhibits the reaction [P2RY12 gene mutant form results in decreased susceptibility to Adenosine Diphosphate] CTD PMID:11413167 NCBI chr 2:145,631,487...145,673,194
Ensembl chr 2:145,629,967...145,633,410 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases cleavage ISO Epinephrine results in decreased cleavage of PARP1 protein CTD PMID:36423730 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression ISO Epinephrine results in increased expression of PCNA protein CTD PMID:36423730 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Phb1 prohibitin 1 multiple interactions
increases expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of PHB1 protein
Epinephrine results in increased expression of PHB1 protein 		CTD PMID:19464573 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP Epinephrine results in increased expression of PHGDH mRNA CTD PMID:12423672 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Pkm pyruvate kinase M1/2 multiple interactions
increases expression 		EXP
ISO 		[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein
Epinephrine results in increased expression of PKM protein 		CTD PMID:19464573 PMID:36423730 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression EXP Epinephrine results in increased expression of PPARGC1A mRNA CTD PMID:22496244 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha decreases expression
multiple interactions 		EXP Epinephrine results in decreased expression of PPP2R1A protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PPP2R1A protein 		CTD PMID:19464573 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression 		EXP [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PRDX6 protein
Epinephrine results in decreased expression of PRDX6 protein 		CTD PMID:19464573 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657 		JBrowse link
G Prkce protein kinase C, epsilon affects response to substance ISO
EXP 		PRKCE protein affects the susceptibility to Epinephrine CTD PMID:11454025 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Epinephrine results in decreased expression of PTGS2 mRNA; Epinephrine results in decreased expression of PTGS2 protein CTD PMID:31520687 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] results in increased activity of [RELA protein binds to NFKB1 protein]]; Epinephrine results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:19135123 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin multiple interactions
increases activity 		ISO ICI 118551 inhibits the reaction [Epinephrine results in increased activity of REN protein] CTD PMID:6314140 PMID:8592096 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Sct secretin multiple interactions EXP Epinephrine inhibits the reaction [SCT protein results in increased abundance of Cyclic AMP] CTD PMID:6312992 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:205,812,435...205,813,246 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Epinephrine results in increased expression of SERPINE1 mRNA CTD PMID:15850565 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
increases uptake 		EXP
ISO 		[Corticosterone results in decreased activity of SLC22A3 protein] inhibits the reaction [Epinephrine results in increased abundance of Epinephrine metabolite]; [Corticosterone results in decreased activity of SLC22A3 protein] which results in decreased abundance of Epinephrine
SLC22A3 protein results in increased uptake of Epinephrine 		CTD PMID:19053318 PMID:20858707 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 increases uptake ISO SLC29A4 protein results in increased uptake of Epinephrine CTD PMID:20858707 NCBI chr12:16,967,047...16,998,276
Ensembl chr12:16,967,047...16,988,338 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
affects binding
increases expression
increases activity 		ISO
EXP 		6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Epinephrine results in increased activity of SOD1 protein]; Atenolol inhibits the reaction [Epinephrine results in increased activity of SOD1 protein]; Vitamin E inhibits the reaction [Epinephrine results in increased activity of SOD1 protein]
Epinephrine binds to SOD1 protein mutant form
[Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of SOD1 protein
Epinephrine results in increased expression of SOD1 protein
Epinephrine results in increased expression of SOD1 mRNA; Epinephrine results in increased expression of SOD1 protein 		CTD PMID:11163531 PMID:19464573 PMID:23612299 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
increases activity 		ISO
EXP 		6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Epinephrine results in increased activity of SOD2 protein]; Atenolol inhibits the reaction [Epinephrine results in increased activity of SOD2 protein]; Vitamin E inhibits the reaction [Epinephrine results in increased activity of SOD2 protein]
[Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of SOD2 protein
Epinephrine results in increased expression of SOD2 protein
Epinephrine results in increased expression of SOD2 mRNA; Epinephrine results in increased expression of SOD2 protein 		CTD PMID:11163531 PMID:19464573 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta increases expression EXP Epinephrine results in increased expression of SUCLG2 protein CTD PMID:19464573 NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296 		JBrowse link
G Th tyrosine hydroxylase increases chemical synthesis
multiple interactions 		ISO
EXP 		TH protein results in increased chemical synthesis of Epinephrine
[Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine 		CTD PMID:9822156 PMID:19067675 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thy1 Thy-1 cell surface antigen multiple interactions
decreases expression 		ISO Propranolol inhibits the reaction [Epinephrine results in decreased expression of THY1] CTD PMID:7558147 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
decreases secretion 		ISO
EXP 		Epinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Epinephrine results in decreased expression of TNF mRNA
Epinephrine results in decreased secretion of TNF protein 		CTD PMID:10588509 PMID:12423672 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Epinephrine results in decreased expression of TP53 protein CTD PMID:36423730 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression
multiple interactions 		EXP Epinephrine results in increased expression of VDAC1 protein
[Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of VDAC1 protein 		CTD PMID:19464573 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Wnt4 Wnt family member 4 decreases expression ISO Epinephrine results in decreased expression of WNT4 mRNA; Epinephrine results in decreased expression of WNT4 protein CTD PMID:31520687 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:154,797,311...154,817,128 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [Epinephrine co-treated with Xanthine co-treated with XDH] affects the expression of MYL2 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of AK2 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DES protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of DLAT protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of ECHS1 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of ETFB protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of FABP3 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HADH protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSP90AB1 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSPA9 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of HSPB6 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of IDH2 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PKM protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PPP2R1A protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of PRDX6 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in decreased expression of SOD2 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of C1QBP protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of CYCS protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of HSPA5 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of PHB1 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of SOD1 protein; [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of VDAC1 protein; Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] affects the localization of HSF1 protein]; Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] results in increased activity of [RELA protein binds to NFKB1 protein]]; Epinephrine promotes the reaction [[Xanthine co-treated with XDH protein] results in increased activity of CASP3 protein] CTD PMID:19135123 PMID:19464573 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
(R)-noradrenaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase multiple interactions
increases activity 		EXP 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid inhibits the reaction [Norepinephrine results in increased activity of AANAT protein]; Cannabidiol inhibits the reaction [Norepinephrine results in increased activity of AANAT protein]; Cannabinol inhibits the reaction [Norepinephrine results in increased activity of AANAT protein] CTD PMID:16805813 NCBI chr10:102,323,647...102,330,639
Ensembl chr10:102,326,135...102,330,635 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle increases expression EXP Norepinephrine results in increased expression of ACTA1 mRNA CTD PMID:17592507 NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions 		ISO Norepinephrine results in increased expression of ACTA2 mRNA
[Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of ACTA2 mRNA]; Carnosine inhibits the reaction [Norepinephrine results in increased expression of ACTA2 mRNA]; FPS-ZM1 inhibits the reaction [Norepinephrine results in increased expression of ACTA2 mRNA] 		CTD PMID:34609854 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Ada adenosine deaminase multiple interactions
decreases response to substance 		ISO
EXP 		[ADA protein co-treated with Norepinephrine] results in increased secretion of Glycerol
Propranolol promotes the reaction [ADA protein results in decreased susceptibility to Norepinephrine] 		CTD PMID:7949234 PMID:17428236 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adra1a adrenoceptor alpha 1A affects binding
multiple interactions
increases activity
affects expression
affects response to substance 		ISO
EXP 		Norepinephrine binds to ADRA1A protein
[Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; Norepinephrine binds to and results in increased activity of ADRA1A protein; Norepinephrine inhibits the reaction [ADRA1A protein binds to Prazosin]
Norepinephrine results in increased activity of ADRA1A protein
5-methylurapidil inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; [chlorethylclonidine co-treated with Phenoxybenzamine] inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; BMY 7378 inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; chlorethylclonidine inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; Phenoxybenzamine inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; Prazosin inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]; Spiperone inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein]
Norepinephrine affects the expression of ADRA1A protein
ADRA1A protein affects the susceptibility to Norepinephrine 		CTD PMID:8183249 PMID:10416824 PMID:12417256 PMID:20030735 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; Norepinephrine binds to and results in increased activity of ADRA1B protein; Norepinephrine inhibits the reaction [ADRA1B protein binds to Prazosin] CTD PMID:20030735 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding
multiple interactions
affects response to substance 		ISO
EXP 		Norepinephrine binds to ADRA1D protein
[Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; Norepinephrine binds to and results in increased activity of ADRA1D protein; Norepinephrine inhibits the reaction [ADRA1D protein binds to Prazosin]
ADRA1D affects the susceptibility to Norepinephrine
Norepinephrine binds to and affects the activity of ADRA1D protein 		CTD PMID:8183249 PMID:9639061 PMID:11901185 PMID:15493479 PMID:20030735 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A affects secretion
multiple interactions
affects abundance
affects binding 		EXP
ISO 		ADRA2A protein affects the secretion of Norepinephrine
[ADRA2A protein mutant form co-treated with ADRA2C protein mutant form] results in increased abundance of Norepinephrine
ADRA2A protein affects the abundance of Norepinephrine
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Dexmedetomidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Doxazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Norepinephrine binds to and results in increased activity of ADRA2A protein; Norepinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; Prazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; talipexole inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Thapsigargin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Yohimbine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]
Norepinephrine binds to ADRA2A protein
[BRL 44408 binds to and results in decreased activity of ADRA2A protein] inhibits the reaction [Xylazine inhibits the reaction [Potassium results in increased secretion of Norepinephrine]] 		CTD PMID:10336518 PMID:10742289 PMID:11312645 PMID:20030735 PMID:20083574 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; Norepinephrine binds to and results in increased activity of ADRA2B protein; Norepinephrine inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] CTD PMID:20030735 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C affects binding
multiple interactions 		ISO Norepinephrine binds to ADRA2C protein
[ADRA2A protein mutant form co-treated with ADRA2C protein mutant form] results in increased abundance of Norepinephrine
[Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; Norepinephrine binds to and results in increased activity of ADRA2C protein; Norepinephrine inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan] 		CTD PMID:10336518 PMID:20030735 PMID:20083574 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions ISO
EXP 		[Norepinephrine binds to and results in increased activity of ADRB1 protein] which results in increased abundance of Cyclic AMP; Norepinephrine binds to and results in increased activity of ADRB1 protein; Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Norepinephrine inhibits the reaction [Iodocyanopindolol binds to ADRB1 protein]; Norepinephrine promotes the reaction [ADRB1 protein results in increased activity of GNAS protein]; Octopamine inhibits the reaction [Norepinephrine binds to ADRB1 protein]; Propranolol inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRB1 protein]
[CGP 20712A binds to and results in decreased activity of ADRB1 protein] which results in decreased activity of Norepinephrine 		CTD PMID:8096834 PMID:10344530 PMID:12010770 PMID:14730417 PMID:17200720 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
affects binding 		EXP
ISO 		[ICI 118551 binds to and results in decreased activity of ADRB2 protein] inhibits the reaction [Fenoterol affects the abundance of Norepinephrine]
[Norepinephrine binds to and results in increased activity of ADRB2 protein] which results in increased abundance of Cyclic AMP; Norepinephrine binds to and results in increased activity of ADRB2 protein; Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB2 protein]; Octopamine inhibits the reaction [Norepinephrine binds to ADRB2 protein]; Propranolol inhibits the reaction [Norepinephrine binds to ADRB2 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine binds to ADRB2 protein] 		CTD PMID:7969507 PMID:10344530 PMID:14730417 PMID:24929186 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases activity 		ISO
EXP 		[Norepinephrine binds to and results in increased activity of ADRB3 protein] which results in increased abundance of Cyclic AMP; Norepinephrine binds to and results in increased activity of ADRB3 protein; Norepinephrine inhibits the reaction [cyanopindolol binds to ADRB3 protein]; Octopamine inhibits the reaction [Norepinephrine binds to ADRB3 protein]
Norepinephrine results in increased activity of ADRB3 protein
3-(2-ethylphenoxy)-1-(1,2,3,4-tetrahydronaphth-1-ylamino)-2-propanol oxalate inhibits the reaction [Norepinephrine results in increased activity of ADRB3 protein]; Norepinephrine binds to and results in increased activity of ADRB3 protein 		CTD PMID:1682311 PMID:7815362 PMID:8569714 PMID:10344530 PMID:14730417 More... NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Agt angiotensinogen increases abundance
affects abundance
multiple interactions 		EXP AGT protein results in increased abundance of Norepinephrine
Norepinephrine affects the abundance of AGT protein
carvedilol inhibits the reaction [AGT protein results in increased abundance of Norepinephrine]; Losartan inhibits the reaction [AGT protein results in increased abundance of Norepinephrine] 		CTD PMID:614752 PMID:15741261 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 affects response to substance ISO AGTR2 protein affects the susceptibility to Norepinephrine CTD PMID:11714657 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Norepinephrine results in decreased expression of AKT1 protein modified form CTD PMID:16338971 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression EXP Norepinephrine results in increased expression of ALOX5AP mRNA CTD PMID:14618266 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038 		JBrowse link
G Anxa1 annexin A1 multiple interactions ISO ANXA1 affects the reaction [Norepinephrine results in decreased secretion of IL6 protein] CTD PMID:16835395 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Aqp2 aquaporin 2 decreases expression EXP Norepinephrine results in decreased expression of AQP2 protein CTD PMID:16788141 NCBI chr 7:132,590,286...132,595,321
Ensembl chr 7:132,590,225...132,595,319 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects abundance
decreases expression 		ISO
EXP 		ATP2A2 protein affects the abundance of Norepinephrine
Norepinephrine results in decreased expression of ATP2A2 mRNA 		CTD PMID:17592507 PMID:19328205 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Avp arginine vasopressin multiple interactions EXP [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA CTD PMID:11742803 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		EXP N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in increased expression of BAX protein]
Norepinephrine results in increased expression of BAX mRNA; Norepinephrine results in increased expression of BAX protein 		CTD PMID:18675472 PMID:20374255 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in decreased expression of BCL2 protein]; N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in decreased expression of BCL2 protein] CTD PMID:14732211 PMID:17041759 PMID:20374255 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP Norepinephrine results in decreased expression of BCL2L1 mRNA CTD PMID:18675472 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bdkrb2 bradykinin receptor B2 affects response to substance ISO BDKRB2 affects the susceptibility to Norepinephrine CTD PMID:12105144 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G C5ar2 complement C5a receptor 2 increases expression EXP Norepinephrine results in increased expression of C5AR2 mRNA; Norepinephrine results in increased expression of C5AR2 protein CTD PMID:15715664 NCBI chr 1:86,058,557...86,073,583
Ensembl chr 1:86,057,256...86,061,372 		JBrowse link
G Calca calcitonin-related polypeptide alpha affects response to substance
increases abundance
multiple interactions 		EXP CALCA protein affects the susceptibility to Norepinephrine
CALCA protein results in increased abundance of Norepinephrine
Propranolol promotes the reaction [CALCA protein affects the susceptibility to Norepinephrine] 		CTD PMID:8058111 PMID:18055875 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Caly calcyon neuron-specific vesicular protein increases secretion ISO CALY protein results in increased secretion of Norepinephrine CTD PMID:30753204 NCBI chr 1:204,292,317...204,303,506
Ensembl chr 1:204,292,318...204,303,196 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression EXP Norepinephrine results in increased expression of CAMK2B mRNA CTD PMID:14618266 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Casp12 caspase 12 multiple interactions
increases cleavage 		EXP CAT protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP12 protein alternative form] CTD PMID:16338971 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:10,926,994...10,954,442 		JBrowse link
G Casp2 caspase 2 multiple interactions
increases activity 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:14732211 PMID:15158148 PMID:17041759 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases cleavage
increases expression 		ISO
EXP 		Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein]; Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein
Norepinephrine results in increased activity of CASP3 protein
Norepinephrine results in increased cleavage of CASP3 protein
Norepinephrine results in increased expression of CASP3 protein
Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in increased expression of CASP3 protein]; Norepinephrine inhibits the reaction [Okadaic Acid results in increased activity of CASP3 protein] 		CTD PMID:11099166 PMID:14732211 PMID:15158148 PMID:16338971 PMID:17041759 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp6 caspase 6 multiple interactions
increases activity 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] CTD PMID:14732211 PMID:15158148 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:221,140,256...221,152,726 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]; Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein CTD PMID:17136323 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 affects activity EXP Norepinephrine affects the activity of CASP8 protein CTD PMID:25437044 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 multiple interactions
affects activity
increases cleavage
increases activity 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]
Norepinephrine affects the activity of CASP9 protein
Norepinephrine results in increased cleavage of CASP9 protein 		CTD PMID:14732211 PMID:15158148 PMID:16338971 PMID:25437044 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [Norepinephrine results in increased cleavage of CASP12 protein alternative form] CTD PMID:16338971 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL3 mRNA]; Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]; Norepinephrine inhibits the reaction [Thioglycolates results in increased secretion of CCL3 protein]; Propranolol inhibits the reaction [Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein]] CTD PMID:9863660 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases secretion
multiple interactions 		ISO Norepinephrine results in increased secretion of CCL5 protein
Prazosin inhibits the reaction [Norepinephrine results in increased secretion of CCL5 protein] 		CTD PMID:16782692 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Norepinephrine results in increased expression of CCN1 mRNA CTD PMID:15117851 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP Norepinephrine results in decreased expression of CITED4 mRNA CTD PMID:14618266 NCBI chr 5:139,532,165...139,533,056
Ensembl chr 5:139,531,584...139,533,361 		JBrowse link
G Cnr1 cannabinoid receptor 1 affects expression ISO Norepinephrine affects the expression of CNR1 mRNA CTD PMID:29650773 NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression 		EXP
ISO 		carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]; Doxazosin inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]
[Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]; FPS-ZM1 inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA] 		CTD PMID:10722803 PMID:14577597 PMID:19575289 PMID:34609854 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions 		EXP
ISO 		Norepinephrine results in increased expression of COL3A1 mRNA
[Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]; Carnosine inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]; FPS-ZM1 inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]
carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA] 		CTD PMID:10722803 PMID:14577597 PMID:34609854 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions
increases methylation 		ISO [tolcapone results in decreased activity of COMT protein] which results in increased abundance of Norepinephrine
COMT protein results in increased methylation of Norepinephrine 		CTD PMID:11160877 PMID:11248589 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression EXP Norepinephrine results in decreased expression of CPT1A mRNA CTD PMID:19109942 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Crem cAMP responsive element modulator increases expression ISO Norepinephrine results in increased expression of CREM mRNA CTD PMID:11171092 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases abundance 		EXP corticotropin releasing hormone (9-41) inhibits the reaction [CRH protein affects the abundance of Norepinephrine]; Norepinephrine affects the expression of and affects the secretion of CRH protein; Propranolol affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein]; Yohimbine affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein]
CRH results in increased abundance of Norepinephrine 		CTD PMID:1320258 PMID:3497798 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 multiple interactions EXP [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Morphine deficiency affects the abundance of Norepinephrine]; [CP 154526 binds to and results in decreased activity of CRHR1 protein] inhibits the reaction [Naloxone affects the abundance of Norepinephrine] CTD PMID:24398105 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,540,192...89,583,466 		JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP Norepinephrine results in increased expression of CROT mRNA CTD PMID:14618266 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064 		JBrowse link
G Cycs cytochrome c, somatic affects localization
increases localization 		EXP Norepinephrine affects the localization of CYCS protein
Norepinephrine results in increased localization of CYCS protein 		CTD PMID:16338971 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Dbh dopamine beta-hydroxylase affects abundance
increases abundance
decreases abundance 		ISO DBH gene polymorphism affects the abundance of Norepinephrine
DBH protein results in increased abundance of Norepinephrine
DBH mutant form results in decreased abundance of Norepinephrine 		CTD PMID:15148402 PMID:16163519 PMID:18329701 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Norepinephrine results in increased expression of DDIT3 mRNA; Norepinephrine results in increased expression of DDIT3 protein CTD PMID:16338971 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Dnm2 dynamin 2 decreases expression EXP Norepinephrine results in decreased expression of DNM2 mRNA CTD PMID:14618266 NCBI chr 8:28,254,344...28,336,297
Ensembl chr 8:28,254,529...28,336,295 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP Norepinephrine inhibits the reaction [Rotenone results in decreased expression of DRD1 mRNA]; Norepinephrine inhibits the reaction [Rotenone results in decreased expression of DRD1 protein] CTD PMID:20887679 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO
EXP 		[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
Norepinephrine inhibits the reaction [Rotenone results in increased expression of DRD2 mRNA]; Norepinephrine inhibits the reaction [Rotenone results in increased expression of DRD2 protein] 		CTD PMID:8032591 PMID:20887679 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
increases activity
decreases secretion
increases secretion 		EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine]; [EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine; BQ 610 inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine]; BQ 788 inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine]; BQ 788 inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine]; KT 5823 inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine]; Metoprolol inhibits the reaction [Norepinephrine results in increased expression of EDN1 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine]; Picrotoxin inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine]
Norepinephrine results in increased activity of EDN1 promoter 		CTD PMID:11435416 PMID:12184995 PMID:14759557 PMID:16023617 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Edn3 endothelin 3 multiple interactions
decreases secretion
increases secretion 		EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [EDN3 protein results in increased secretion of Norepinephrine]; 2-aminoethoxydiphenyl borate inhibits the reaction [EDN3 protein results in increased secretion of Norepinephrine]; [EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine; bisindolylmaleimide I inhibits the reaction [EDN3 protein results in increased secretion of Norepinephrine]; BQ 788 inhibits the reaction [EDN3 protein results in decreased secretion of Norepinephrine]; KT 5823 inhibits the reaction [EDN3 protein results in decreased secretion of Norepinephrine]; Picrotoxin inhibits the reaction [EDN3 protein results in decreased secretion of Norepinephrine] CTD PMID:12184995 PMID:14759557 PMID:16023617 NCBI chr 3:183,980,458...184,004,958
Ensembl chr 3:183,980,668...184,005,329 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] which results in decreased susceptibility to Norepinephrine CTD PMID:15834289 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP [EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine; [EDN3 protein binds to and results in increased activity of EDNRB protein] which results in decreased secretion of Norepinephrine CTD PMID:16023617 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Efhd2 EF-hand domain family, member D2 increases secretion ISO EFHD2 gene mutant form results in increased secretion of Norepinephrine CTD PMID:28397836 NCBI chr 5:159,443,959...159,459,993
Ensembl chr 5:159,443,960...159,460,369 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [EGF protein co-treated with Norepinephrine] results in increased expression of MYC mRNA CTD PMID:11742803 PMID:12632255 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP EGFR protein inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form] CTD PMID:19168439 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egr1 early growth response 1 increases expression EXP Norepinephrine results in increased expression of EGR1 CTD PMID:7905536 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of ELK1 protein] CTD PMID:11880281 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions
increases expression 		ISO [Dexamethasone co-treated with Norepinephrine] results in increased expression of ELOVL3 mRNA; Dactinomycin inhibits the reaction [Norepinephrine results in increased expression of ELOVL3 mRNA]; Norepinephrine results in increased expression of and results in decreased degradation of ELOVL3 mRNA; rosiglitazone promotes the reaction [[Dexamethasone co-treated with Norepinephrine] results in increased expression of ELOVL3 mRNA] CTD PMID:17726147 NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:254,938,731...254,942,559 		JBrowse link
G Epo erythropoietin decreases response to substance ISO EPO protein results in decreased susceptibility to Norepinephrine CTD PMID:14732207 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
increases expression 		ISO Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; Norepinephrine promotes the reaction [REL protein binds to F3 promoter]; Norepinephrine promotes the reaction [RELA protein binds to F3 promoter]; prolinedithiocarbamate inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; REL mutant form inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] CTD PMID:23114885 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions EXP [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; KT 5720 inhibits the reaction [Norepinephrine inhibits the reaction [Carbachol results in increased expression of FGF1 protein]]; Norepinephrine inhibits the reaction [Carbachol results in increased expression of FGF1 protein] CTD PMID:11742803 PMID:15264218 NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,939,870...30,961,393 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]] CTD PMID:11742803 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression EXP Norepinephrine results in increased expression of FGR mRNA CTD PMID:14618266 NCBI chr 5:150,473,767...150,503,524
Ensembl chr 5:150,473,792...150,503,169 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Norepinephrine co-treated with Prazosin] results in decreased expression of FN1 protein; [Norepinephrine co-treated with Propranolol] results in increased expression of FN1 protein CTD PMID:11821714 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fndc5 fibronectin type III domain containing 5 decreases abundance EXP FNDC5 protein results in decreased abundance of Norepinephrine CTD PMID:32165127 NCBI chr 5:146,765,951...146,775,611
Ensembl chr 5:146,751,416...146,778,540 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions 		ISO
EXP 		Norepinephrine results in increased expression of FOS mRNA
Norepinephrine results in increased expression of FOS; Norepinephrine results in increased expression of FOS mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of FOS mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of FOS mRNA]; bisindolylmaleimide inhibits the reaction [Norepinephrine results in increased expression of FOS mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of FOS mRNA] 		CTD PMID:7605896 PMID:7905536 PMID:12729908 PMID:19225867 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Norepinephrine results in increased expression of FOSB CTD PMID:7905536 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions
increases phosphorylation 		EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of FOXO3 protein]; SHC1 protein affects the reaction [Norepinephrine results in increased phosphorylation of FOXO3 protein] CTD PMID:19168439 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions
increases expression 		EXP Norepinephrine results in increased activity of G6PD mRNA; Norepinephrine results in increased activity of G6PD protein
Metoprolol inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]; Prazosin inhibits the reaction [Norepinephrine results in increased activity of G6PD protein]
Norepinephrine results in increased expression of G6PD mRNA 		CTD PMID:1378361 PMID:7605896 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144 		JBrowse link
G Gabpa GA binding protein transcription factor subunit alpha multiple interactions EXP [Progesterone co-treated with Norepinephrine] results in increased expression of GABPA mRNA CTD PMID:16954335 NCBI chr11:37,375,040...37,404,060
Ensembl chr11:37,375,084...37,404,059 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP Norepinephrine results in increased expression of GJA1 mRNA CTD PMID:14618266 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gk glycerol kinase increases activity
increases expression 		EXP Norepinephrine results in increased activity of GK protein
Norepinephrine results in increased expression of GK mRNA 		CTD PMID:12736183 NCBI chr  X:54,106,708...54,189,940
Ensembl chr  X:54,112,214...54,196,701 		JBrowse link
G Gnas GNAS complex locus multiple interactions ISO Norepinephrine promotes the reaction [ADRB1 protein results in increased activity of GNAS protein] CTD PMID:17200720 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Gpc3 glypican 3 increases expression EXP Norepinephrine results in increased expression of GPC3 mRNA CTD PMID:14618266 NCBI chr  X:136,789,770...137,157,598
Ensembl chr  X:136,789,770...137,157,639 		JBrowse link
G Hbb hemoglobin subunit beta increases expression EXP Norepinephrine results in increased expression of HBB mRNA CTD PMID:14618266 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:167,630,245...167,663,873 		JBrowse link
G Hdc histidine decarboxylase affects abundance ISO HDC protein affects the abundance of Norepinephrine CTD PMID:12421355 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		ISO Propranolol inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of HMOX1 mRNA] CTD PMID:24929186 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Norepinephrine results in increased expression of HSPA5 mRNA; Norepinephrine results in increased expression of HSPA5 protein CTD PMID:16338971 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions
increases expression 		EXP N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in increased expression of HTR2B protein] CTD PMID:20374255 NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression 		ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Norepinephrine promotes the reaction [RELA protein binds to ICAM1 promoter]]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; bisindolylmaleimide I inhibits the reaction [Norepinephrine promotes the reaction [NFKB1 protein binds to ICAM1 promoter]]; bisindolylmaleimide I inhibits the reaction [Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]]; NFKB1 mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Norepinephrine promotes the reaction [NFKB1 protein binds to ICAM1 promoter]; Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]; Norepinephrine promotes the reaction [RELA protein binds to ICAM1 promoter]; prolinedithiocarbamate inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; REL mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; wortmannin inhibits the reaction [Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]] CTD PMID:23114885 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases response to substance 		EXP Prazosin inhibits the reaction [IGF1 protein results in decreased susceptibility to Norepinephrine] CTD PMID:17184500 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Il1b interleukin 1 beta affects secretion
increases expression
multiple interactions 		EXP Norepinephrine affects the secretion of IL1B protein
Norepinephrine results in increased expression of IL1B mRNA
carvedilol inhibits the reaction [Norepinephrine results in increased expression of IL1B mRNA]; Norepinephrine promotes the reaction [IL1B protein results in increased expression of IL6 protein] 		CTD PMID:8392517 PMID:10722803 PMID:16386803 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
increases activity
decreases secretion 		ISO
EXP 		Norepinephrine results in increased expression of and results in increased secretion of IL6 protein; sulforaphane inhibits the reaction [Norepinephrine results in increased expression of and results in increased secretion of IL6 protein]
Norepinephrine results in increased expression of IL6 mRNA; Norepinephrine results in increased expression of IL6 protein
Norepinephrine results in increased activity of IL6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; Carvedilol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; ICI 118551 inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; Metoprolol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]; Norepinephrine promotes the reaction [IL1B protein results in increased expression of IL6 protein]; Norepinephrine promotes the reaction [TNF protein results in increased expression of IL6 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA]
Norepinephrine results in decreased secretion of IL6 protein
ANXA1 affects the reaction [Norepinephrine results in decreased secretion of IL6 protein] 		CTD PMID:8392517 PMID:10722803 PMID:11406463 PMID:12619890 PMID:14577597 More... NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP INS1 protein inhibits the reaction [[Theophylline co-treated with Norepinephrine] results in increased abundance of Cyclic AMP] CTD PMID:4306506 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
increases expression 		EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of JUN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of JUN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of JUN protein]; bisindolylmaleimide inhibits the reaction [Norepinephrine results in increased expression of JUN mRNA]; bisindolylmaleimide inhibits the reaction [Norepinephrine results in increased phosphorylation of JUN protein]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of JUN mRNA]; pyrazolanthrone inhibits the reaction [Norepinephrine results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of JUN mRNA]
Norepinephrine results in increased expression of JUN; Norepinephrine results in increased expression of JUN mRNA 		CTD PMID:7905536 PMID:19225867 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Norepinephrine results in increased expression of JUNB CTD PMID:7905536 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 affects response to substance EXP KCNMA1 protein affects the susceptibility to Norepinephrine CTD PMID:22226998 NCBI chr15:351,065...1,057,117
Ensembl chr15:351,659...1,057,117 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Norepinephrine results in decreased secretion of and results in decreased expression of LHB protein; Phenoxybenzamine inhibits the reaction [Norepinephrine results in decreased secretion of and results in decreased expression of LHB protein]; Piperoxan inhibits the reaction [Norepinephrine results in decreased secretion of and results in decreased expression of LHB protein]; Prazosin inhibits the reaction [Norepinephrine results in decreased secretion of and results in decreased expression of LHB protein] CTD PMID:3953791 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Lpl lipoprotein lipase multiple interactions
increases expression 		EXP Prazosin inhibits the reaction [Norepinephrine results in increased expression of LPL mRNA]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of LPL mRNA] CTD PMID:9032464 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Maoa monoamine oxidase A increases metabolic processing
increases abundance 		ISO MAOA protein results in increased metabolism of Norepinephrine
MAOA mutant form results in increased abundance of Norepinephrine 		CTD PMID:10647887 PMID:11834493 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Maob monoamine oxidase B increases abundance ISO MAOB mutant form results in increased abundance of Norepinephrine CTD PMID:11834493 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		ISO
EXP 		Norepinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK1 protein]
Norepinephrine results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK1 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased activity of and results in increased phosphorylation of MAPK1 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein; [Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein; AG 1879 inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased phosphorylation of MAPK1 protein]; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Carvedilol inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Egtazic Acid inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein]; Gadolinium inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; N-(8-aminooctyl)-5-iodonaphthalene-1-sulfonamide inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein]; Norepinephrine results in increased activity of and results in increased phosphorylation of MAPK1 protein; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Prazosin affects the reaction [Norepinephrine results in increased activity of and results in increased phosphorylation of MAPK1 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK1 protein]; Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; W 7 inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK1 protein] 		CTD PMID:10788502 PMID:11054474 PMID:11880281 PMID:11914123 PMID:15292328 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 multiple interactions ISO MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Norepinephrine] CTD PMID:16949803 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		ISO
EXP 		Norepinephrine inhibits the reaction [Estradiol results in decreased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK3 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased activity of and results in increased phosphorylation of MAPK3 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein]; [Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein; [Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein; AG 1879 inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased phosphorylation of MAPK3 protein]; Cadmium Chloride inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; cadmium sulfate inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Egtazic Acid inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein]; Gadolinium inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; N,N'-bis(salicylideneamino)ethane-manganese(II) inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; N-(8-aminooctyl)-5-iodonaphthalene-1-sulfonamide inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein]; Norepinephrine results in increased activity of and results in increased phosphorylation of MAPK3 protein; oxophenylarsine inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Prazosin inhibits the reaction [[Norepinephrine co-treated with Propranolol] results in increased phosphorylation of MAPK3 protein]; Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; W 7 inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of and results in increased phosphorylation of MAPK3 protein] 		CTD PMID:10788502 PMID:11054474 PMID:11880281 PMID:11914123 PMID:15292328 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein] CTD PMID:17041759 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
affects response to substance 		ISO MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Norepinephrine] CTD PMID:16949803 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
increases activity 		EXP
ISO 		Cromolyn Sodium inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; Metoprolol inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; Norepinephrine results in increased activity of and results in increased expression of MMP2 protein; Prazosin inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; trans-sodium crocetinate inhibits the reaction [Norepinephrine results in increased activity of MMP2 protein]; trans-sodium crocetinate inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]
Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Norepinephrine results in increased expression of MMP2 mRNA] 		CTD PMID:14577597 PMID:15326086 PMID:16864425 PMID:24929186 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
increases activity 		EXP
ISO 		trans-sodium crocetinate inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]
Norepinephrine results in increased activity of MMP9 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; Propranolol inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased activity of MMP9 protein]; quercetin 3-O-glucuronide inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; SR 11302 inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA]; tanshinone inhibits the reaction [Norepinephrine results in increased expression of MMP9 mRNA] 		CTD PMID:16864425 PMID:24929186 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mt3 metallothionein 3 increases expression EXP Norepinephrine results in increased expression of MT3 mRNA CTD PMID:14618266 NCBI chr19:10,854,676...10,856,080
Ensembl chr19:10,854,677...10,856,080 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression 		EXP [EGF protein co-treated with Norepinephrine] results in increased expression of MYC mRNA
Norepinephrine results in increased expression of MYC 		CTD PMID:7605896 PMID:12632255 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myh11 myosin heavy chain 11 increases expression EXP Norepinephrine results in increased expression of MYH11 mRNA CTD PMID:14618266 NCBI chr10:1,250,554...1,345,681
Ensembl chr10:1,263,194...1,345,678 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Norepinephrine results in decreased expression of MYH6 mRNA CTD PMID:17592507 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
affects expression
increases expression 		EXP Propranolol promotes the reaction [Norepinephrine results in increased expression of MYH7 mRNA]
Norepinephrine affects the expression of MYH7 mRNA 		CTD PMID:17592507 PMID:25437044 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Myl1 myosin, light chain 1 multiple interactions
increases phosphorylation 		ISO
EXP 		PRKD1 protein affects the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein]
chelerythrine inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein]; CRT 0066101 inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein]; fasudil inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein] 		CTD PMID:37963515 Ensembl chr 9:75,887,227...75,907,971 JBrowse link
G Myl3 myosin light chain 3 decreases expression EXP Norepinephrine results in decreased expression of MYL3 mRNA CTD PMID:14618266 NCBI chr 8:119,617,077...119,623,215
Ensembl chr 8:119,616,868...119,623,216 		JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 decreases expression EXP Norepinephrine results in decreased expression of NAALAD2 mRNA CTD PMID:14618266 NCBI chr 8:23,682,499...23,756,066
Ensembl chr 8:23,683,395...23,756,060 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP Norepinephrine results in increased expression of NFE2L2 mRNA CTD PMID:14618266 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated increases expression ISO Norepinephrine results in increased expression of NFIL3 mRNA CTD PMID:12729908 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
affects localization 		ISO Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine promotes the reaction [NFKB1 protein binds to ICAM1 promoter]]; NFKB1 mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; NFKB1 mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Norepinephrine affects the localization of [NFKB1 protein binds to RELA protein]; Norepinephrine promotes the reaction [[NFKB1 protein binds to RELA protein] which binds to SOD2 promoter]; Norepinephrine promotes the reaction [NFKB1 protein binds to ICAM1 promoter]; Norepinephrine results in increased activity of [NFKB1 protein binds to RELA protein]; prolinedithiocarbamate inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; Vitamin E inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein] CTD PMID:16782692 PMID:23114885 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Ngf nerve growth factor decreases expression EXP Norepinephrine results in decreased expression of NGF mRNA; Norepinephrine results in decreased expression of NGF protein CTD PMID:8593794 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
affects response to substance 		ISO [GW 274150 results in decreased activity of NOS2 protein] which results in increased susceptibility to Norepinephrine; Atenolol inhibits the reaction [Norepinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Atenolol inhibits the reaction [Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Norepinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Prazosin inhibits the reaction [Norepinephrine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Prazosin inhibits the reaction [Norepinephrine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
NOS2 protein affects the susceptibility to Norepinephrine 		CTD PMID:16424707 PMID:19439816 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nppa natriuretic peptide A increases expression
multiple interactions 		ISO
EXP 		Norepinephrine results in increased expression of NPPA mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]; Carvedilol inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Norepinephrine results in increased expression of NPPA mRNA] 		CTD PMID:9788975 PMID:10722803 PMID:14577597 PMID:14618266 PMID:15240149 More... NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B affects abundance
decreases abundance 		ISO NPPB affects the abundance of Norepinephrine
NPPB protein results in decreased abundance of Norepinephrine 		CTD PMID:16333235 PMID:20339970 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Npy neuropeptide Y affects response to substance ISO NPY protein affects the susceptibility to Norepinephrine CTD PMID:15003356 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions EXP [Estradiol co-treated with Norepinephrine] results in decreased expression of NRF1 mRNA CTD PMID:16954335 NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353 		JBrowse link
G Ntf3 neurotrophin 3 increases expression EXP Norepinephrine results in increased expression of NTF3 mRNA; Norepinephrine results in increased expression of NTF3 protein CTD PMID:19854260 NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:160,600,770...160,676,349 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases activity EXP Norepinephrine results in decreased activity of ODC1 protein CTD PMID:1850525 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP [dextrallorphan binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Dextrorphan binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Levallorphan binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Levorphanol binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Methadyl Acetate binds to OPRD1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRD1 protein] which results in decreased uptake of Norepinephrine CTD PMID:7562497 NCBI chr 5:149,590,244...149,624,999
Ensembl chr 5:149,590,244...149,624,999 		JBrowse link
G Oprk1 opioid receptor, kappa 1 multiple interactions EXP [dextrallorphan binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Dextrorphan binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Levallorphan binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Levorphanol binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Methadyl Acetate binds to OPRK1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRK1 protein] which results in decreased uptake of Norepinephrine CTD PMID:7562497 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:18,657,871...18,675,671 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP [dextrallorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextromethorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextropropoxyphene binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Dextrorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Levallorphan binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Levorphanol binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Methadone binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Methadyl Acetate binds to OPRM1 protein] which results in decreased uptake of Norepinephrine; [Tramadol binds to OPRM1 protein] which results in decreased uptake of Norepinephrine CTD PMID:7562497 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Pak3 p21 (RAC1) activated kinase 3 decreases expression EXP Norepinephrine results in decreased expression of PAK3 mRNA CTD PMID:14618266 NCBI chr  X:111,912,967...112,171,037
Ensembl chr  X:111,913,059...112,165,035 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases expression EXP Norepinephrine results in increased expression of PAM mRNA CTD PMID:14618266 NCBI chr 9:105,445,812...105,719,287
Ensembl chr 9:105,445,929...105,719,285 		JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Norepinephrine results in increased expression of PER1 mRNA CTD PMID:12729908 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211 		JBrowse link
G Per2 period circadian regulator 2 increases expression ISO Norepinephrine results in increased expression of PER2 mRNA CTD PMID:12729908 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression EXP Norepinephrine results in increased expression of PEX2 mRNA CTD PMID:14618266 NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:97,948,443...97,981,092 		JBrowse link
G Pgd phosphogluconate dehydrogenase multiple interactions
increases activity 		EXP carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD protein] CTD PMID:1378361 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression EXP Norepinephrine results in increased expression of PIK3C3 mRNA CTD PMID:14618266 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539 		JBrowse link
G Plcb1 phospholipase C beta 1 increases activity
multiple interactions
increases expression 		EXP Norepinephrine results in increased activity of PLCB1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCB1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCB1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCB1 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB1 mRNA]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB1 protein]; Norepinephrine results in increased expression of and results in increased activity of PLCB1 protein; Prazosin inhibits the reaction [Norepinephrine results in increased expression of and results in increased activity of PLCB1 protein]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCB1 mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCB1 protein]; pyrazolanthrone inhibits the reaction [Norepinephrine results in increased expression of PLCB1 mRNA]
Norepinephrine results in increased expression of PLCB1 mRNA; Norepinephrine results in increased expression of PLCB1 protein 		CTD PMID:16714034 PMID:19225867 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646 		JBrowse link
G Plcb3 phospholipase C beta 3 increases activity
multiple interactions
increases expression 		EXP Norepinephrine results in increased activity of PLCB3 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCB3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCB3 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCB3 protein]; Norepinephrine results in increased expression of and results in increased activity of PLCB3 protein; Prazosin inhibits the reaction [Norepinephrine results in increased expression of and results in increased activity of PLCB3 protein]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCB3 protein]; pyrazolanthrone inhibits the reaction [Norepinephrine results in increased expression of PLCB3 mRNA]
Norepinephrine results in increased expression of PLCB3 mRNA; Norepinephrine results in increased expression of PLCB3 protein 		CTD PMID:16714034 PMID:19225867 NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583 		JBrowse link
G Plcd1 phospholipase C, delta 1 increases activity
multiple interactions
increases expression 		EXP Norepinephrine results in increased activity of PLCD1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCD1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCD1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCD1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCD1 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCD1 mRNA]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCD1 protein]; Norepinephrine results in increased expression of and results in increased activity of PLCD1 protein; Prazosin inhibits the reaction [Norepinephrine results in increased expression of and results in increased activity of PLCD1 protein]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCD1 mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCD1 protein]; pyrazolanthrone inhibits the reaction [Norepinephrine results in increased expression of PLCD1 mRNA]
Norepinephrine results in increased expression of PLCD1 mRNA; Norepinephrine results in increased expression of PLCD1 protein 		CTD PMID:16714034 PMID:19225867 NCBI chr 8:127,672,955...127,695,939
Ensembl chr 8:127,672,980...127,695,939 		JBrowse link
G Plcg1 phospholipase C, gamma 1 increases activity
multiple interactions
increases expression 		EXP Norepinephrine results in increased activity of PLCG1 protein
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCG1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Norepinephrine results in increased expression of PLCG1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCG1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Norepinephrine results in increased expression of PLCG1 protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCG1 mRNA]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased expression of PLCG1 protein]; Norepinephrine results in increased expression of and results in increased activity of PLCG1 protein; Prazosin inhibits the reaction [Norepinephrine results in increased expression of and results in increased activity of PLCG1 protein]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCG1 mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of PLCG1 protein]
Norepinephrine results in increased expression of PLCG1 mRNA; Norepinephrine results in increased expression of PLCG1 protein 		CTD PMID:16714034 PMID:19225867 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Pmpcb peptidase, mitochondrial processing subunit beta decreases expression EXP Norepinephrine results in decreased expression of PMPCB mRNA CTD PMID:14618266 NCBI chr 4:14,189,807...14,202,584
Ensembl chr 4:14,165,844...14,202,615 		JBrowse link
G Pnlip pancreatic lipase increases expression EXP Norepinephrine results in increased expression of PNLIP mRNA CTD PMID:14618266 NCBI chr 1:267,760,073...267,797,797
Ensembl chr 1:267,784,724...267,797,795 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression EXP Norepinephrine results in increased expression of PPARA mRNA CTD PMID:19109942 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP Norepinephrine results in increased expression of PPARG mRNA CTD PMID:19109942 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
increases expression 		ISO
EXP 		[Propranolol co-treated with Prazosin] inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of PPARGC1A mRNA]
Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PPARGC1A mRNA] 		CTD PMID:16513826 PMID:16954335 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
multiple interactions 		EXP
ISO 		Norepinephrine results in increased phosphorylation of PPP1R12A protein
PRKD1 protein affects the reaction [Norepinephrine results in increased phosphorylation of PPP1R12A protein]
CRT 0066101 inhibits the reaction [Norepinephrine results in increased phosphorylation of PPP1R12A protein]; fasudil inhibits the reaction [Norepinephrine results in increased phosphorylation of PPP1R12A protein] 		CTD PMID:37963515 NCBI chr 7:45,368,922...45,480,158
Ensembl chr 7:45,369,315...45,480,157 		JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A increases phosphorylation
multiple interactions 		EXP Norepinephrine results in increased phosphorylation of PPP1R14A protein
chelerythrine inhibits the reaction [Norepinephrine results in increased phosphorylation of PPP1R14A protein] 		CTD PMID:37963515 NCBI chr 1:93,708,269...93,718,218
Ensembl chr 1:93,708,218...93,719,147 		JBrowse link
G Prkd1 protein kinase D1 multiple interactions
increases phosphorylation 		ISO
EXP 		PRKD1 protein affects the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein]; PRKD1 protein affects the reaction [Norepinephrine results in increased phosphorylation of PPP1R12A protein]
CRT 0066101 inhibits the reaction [Norepinephrine results in increased phosphorylation of PRKD1 protein] 		CTD PMID:37963515 NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:73,460,640...73,836,509 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions EXP [Estradiol co-treated with Norepinephrine] results in decreased expression of PTEN mRNA; [Progesterone co-treated with Norepinephrine] results in increased expression of PTEN mRNA; Norepinephrine inhibits the reaction [Testosterone results in decreased expression of PTEN mRNA] CTD PMID:16954335 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Norepinephrine CTD PMID:15834289 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated affects expression EXP Norepinephrine affects the expression of PYGM mRNA CTD PMID:14618266 NCBI chr 1:213,119,805...213,134,622
Ensembl chr 1:213,119,791...213,134,612 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions
affects localization 		ISO Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of REL protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of REL protein]; bisindolylmaleimide I inhibits the reaction [Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]]; Norepinephrine promotes the reaction [REL protein binds to F3 promoter]; Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]; prolinedithiocarbamate inhibits the reaction [Norepinephrine affects the localization of REL protein]; REL mutant form inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; REL mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Vitamin E inhibits the reaction [Norepinephrine affects the localization of REL protein]; wortmannin inhibits the reaction [Norepinephrine affects the localization of REL protein]; wortmannin inhibits the reaction [Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]] CTD PMID:23114885 NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization 		ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Norepinephrine affects the localization of RELA protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Norepinephrine promotes the reaction [RELA protein binds to ICAM1 promoter]]; Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of RELA protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of RELA protein]; Norepinephrine affects the localization of [NFKB1 protein binds to RELA protein]; Norepinephrine promotes the reaction [[NFKB1 protein binds to RELA protein] which binds to SOD2 promoter]; Norepinephrine promotes the reaction [RELA protein binds to F3 promoter]; Norepinephrine promotes the reaction [RELA protein binds to ICAM1 promoter]; Norepinephrine results in increased activity of [NFKB1 protein binds to RELA protein]; prolinedithiocarbamate inhibits the reaction [Norepinephrine affects the localization of RELA protein]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Vitamin E inhibits the reaction [Norepinephrine affects the localization of RELA protein] CTD PMID:16782692 PMID:23114885 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO Norepinephrine results in increased expression of S100A8 mRNA; Norepinephrine results in increased expression of S100A8 protein CTD PMID:16677282 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO Norepinephrine results in increased expression of S100A9 mRNA; Norepinephrine results in increased expression of S100A9 protein CTD PMID:16677282 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G S100b S100 calcium binding protein B increases expression
affects response to substance 		ISO Norepinephrine results in increased expression of S100B mRNA; Norepinephrine results in increased expression of S100B protein
S100B protein affects the susceptibility to Norepinephrine 		CTD PMID:9788975 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,348...12,381,081 		JBrowse link
G Safb scaffold attachment factor B increases expression EXP Norepinephrine results in increased expression of SAFB mRNA CTD PMID:14618266 NCBI chr 9:1,504,657...1,525,545
Ensembl chr 9:1,504,456...1,525,781 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression EXP Norepinephrine results in increased expression of SCD1 mRNA CTD PMID:22413010 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Norepinephrine results in increased expression of SERPINE1 mRNA CTD PMID:17429342 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions
increases expression 		EXP carvedilol inhibits the reaction [Norepinephrine results in increased expression of SERPINH1 mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased expression of SERPINH1 protein]
Norepinephrine results in increased expression of SERPINH1 mRNA; Norepinephrine results in increased expression of SERPINH1 protein 		CTD PMID:10722803 NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976 		JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions
increases phosphorylation 		EXP 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; bisindolylmaleimide I inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; EGFR protein inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; Prazosin inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; RTKI cpd inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; SHC1 protein affects the reaction [Norepinephrine results in decreased expression of SOD2 protein]; SHC1 protein affects the reaction [Norepinephrine results in increased phosphorylation of FOXO3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; U 0126 inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form] CTD PMID:19168439 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 decreases expression EXP Norepinephrine results in decreased expression of SLC12A1 protein CTD PMID:16788141 NCBI chr 3:132,859,581...132,936,354
Ensembl chr 3:132,859,590...132,936,340 		JBrowse link
G Slc14a2 solute carrier family 14 member 2 decreases expression EXP Norepinephrine results in decreased expression of SLC14A2 protein CTD PMID:16788141 Ensembl chr18:73,887,575...73,953,570 JBrowse link
G Slc18a1 solute carrier family 18 member A1 multiple interactions ISO Norepinephrine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin] CTD PMID:8245983 NCBI chr16:25,408,485...25,453,786
Ensembl chr16:25,420,243...25,453,786 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions
increases expression
decreases activity
affects binding 		EXP
ISO 		Norepinephrine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]
Norepinephrine results in increased expression of SLC18A2 mRNA
Norepinephrine results in decreased activity of SLC18A2 protein
Norepinephrine binds to SLC18A2 protein 		CTD PMID:1438304 PMID:7912402 PMID:14618266 PMID:15475732 NCBI chr 1:268,399,815...268,435,229
Ensembl chr 1:268,400,016...268,435,231 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake
multiple interactions 		ISO
EXP 		SLC22A3 protein results in increased uptake of Norepinephrine
Norepinephrine affects the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] 		CTD PMID:9830022 PMID:20858707 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc29a4 solute carrier family 29 member 4 increases uptake ISO SLC29A4 protein results in increased uptake of Norepinephrine CTD PMID:20858707 NCBI chr12:16,967,047...16,998,276
Ensembl chr12:16,967,047...16,988,338 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions
increases uptake
decreases expression
decreases uptake
decreases activity 		ISO
EXP 		N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [SLC6A2 protein results in increased uptake of Norepinephrine]; Norepinephrine inhibits the reaction [nisoxetine binds to SLC6A2 protein]; SLC6A2 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein]
[Cullen corylifolium extract results in decreased activity of SLC6A2 protein] which results in decreased uptake of Norepinephrine; Norepinephrine affects the localization of and affects the metabolism of SLC6A2 protein
[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine; Bupivacaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]; Lidocaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]; tricaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]
Norepinephrine results in decreased expression of SLC6A2 protein
SLC6A2 mutant form results in decreased uptake of Norepinephrine
Norepinephrine results in decreased activity of SLC6A2 protein 		CTD PMID:11082428 PMID:11458707 PMID:16338971 PMID:16725121 PMID:17234900 More... NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases uptake 		ISO SLC6A3 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein]
SLC6A3 protein results in increased uptake of Norepinephrine 		CTD PMID:17234900 PMID:17250655 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions ISO SLC6A4 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] CTD PMID:17234900 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 increases expression EXP Norepinephrine results in increased expression of SLC8A1 mRNA; Norepinephrine results in increased expression of SLC8A1 protein CTD PMID:11179087 NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:18,946,798...19,287,964 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
increases expression
multiple interactions 		EXP
ISO 		Norepinephrine results in decreased expression of SOD2 protein
Norepinephrine results in increased expression of SOD2 mRNA
Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; NFKB1 mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Norepinephrine promotes the reaction [[NFKB1 protein binds to RELA protein] which binds to SOD2 promoter]; prolinedithiocarbamate inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; RELA mutant form inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Vitamin E inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]
SHC1 protein affects the reaction [Norepinephrine results in decreased expression of SOD2 protein] 		CTD PMID:19168439 PMID:23114885 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP Norepinephrine results in increased expression of STAR mRNA CTD PMID:14618266 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases phosphorylation 		ISO [Clorgyline co-treated with Selegiline] inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein]; Carnosine inhibits the reaction [Norepinephrine results in increased phosphorylation of STAT3 protein] CTD PMID:34609854 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Syk spleen associated tyrosine kinase increases expression EXP Norepinephrine results in increased expression of SYK mRNA CTD PMID:14618266 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278 		JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions ISO SLC6A2 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein]; SLC6A3 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein]; SLC6A4 protein promotes the reaction [Norepinephrine results in increased activity of TAAR1 protein] CTD PMID:17234900 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Tbxa2r thromboxane A2 receptor multiple interactions EXP [SQ 29548 binds to and results in decreased activity of TBXA2R protein] which results in decreased susceptibility to Norepinephrine CTD PMID:15834289 NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:9,034,108...9,038,905 		JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP [Estradiol co-treated with Norepinephrine] results in decreased expression of TFAM mRNA; [Progesterone co-treated with Norepinephrine] results in increased expression of TFAM mRNA CTD PMID:16954335 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression 		EXP Prazosin inhibits the reaction [Norepinephrine results in increased expression of TGFB1 mRNA] CTD PMID:15326086 PMID:19575289 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression
multiple interactions 		EXP Norepinephrine results in increased expression of TGFB2 mRNA; Norepinephrine results in increased expression of TGFB2 protein
Prazosin inhibits the reaction [Norepinephrine results in increased expression of TGFB2 mRNA] 		CTD PMID:15326086 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions 		EXP Norepinephrine results in increased expression of TGFB3 mRNA
Prazosin inhibits the reaction [Norepinephrine results in increased expression of TGFB3 mRNA] 		CTD PMID:15326086 NCBI chr 6:111,435,170...111,457,646
Ensembl chr 6:111,435,170...111,456,946 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases chemical synthesis 		EXP
ISO 		[Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Norepinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Norepinephrine
TH protein results in increased chemical synthesis of Norepinephrine 		CTD PMID:9822156 PMID:19067675 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression
multiple interactions 		ISO Norepinephrine results in decreased expression of THY1
Propranolol inhibits the reaction [Norepinephrine results in decreased expression of THY1] 		CTD PMID:7558147 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 increases expression EXP Norepinephrine results in increased expression of TIMM13 mRNA CTD PMID:14618266 NCBI chr 7:9,459,490...9,460,849
Ensembl chr 7:9,459,582...9,460,862 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions
increases expression 		EXP Metoprolol inhibits the reaction [Norepinephrine results in increased expression of TIMP2 mRNA]; Prazosin inhibits the reaction [Norepinephrine results in increased expression of TIMP2 mRNA] CTD PMID:14577597 PMID:15326086 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion 		EXP Acetylcysteine inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Norepinephrine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; Norepinephrine promotes the reaction [TNF protein results in increased expression of IL6 protein]
Norepinephrine results in increased expression of TNF mRNA 		CTD PMID:8392517 PMID:15081246 PMID:15158148 PMID:25437044 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Norepinephrine results in increased expression of TP53 mRNA CTD PMID:14618266 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions
increases expression 		ISO
EXP 		[Rosiglitazone results in increased susceptibility to Norepinephrine] which results in increased expression of UCP1 mRNA; [Rosiglitazone results in increased susceptibility to Norepinephrine] which results in increased expression of UCP1 protein; AG 1879 promotes the reaction [Norepinephrine results in increased expression of UCP1 mRNA]
[AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF1 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine promotes the reaction [FGF2 protein results in increased expression of UCP1 mRNA]]; [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine results in increased expression of UCP1 mRNA]; [EGF protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [FGF1 protein co-treated with AVP protein co-treated with Norepinephrine co-treated with Triiodothyronine] results in decreased expression of UCP1 mRNA; [Triiodothyronine co-treated with Norepinephrine] results in increased expression of UCP1 mRNA 		CTD PMID:10465291 PMID:10788502 PMID:11742803 PMID:29910772 PMID:31048375 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420 		JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP Norepinephrine results in increased expression of UCP2 mRNA CTD PMID:8593794 PMID:12588052 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743 		JBrowse link
G Usf1 upstream transcription factor 1 multiple interactions ISO USF1 gene polymorphism promotes the reaction [Norepinephrine results in increased metabolism of Lipids]; USF1 protein affects the reaction [Norepinephrine results in increased metabolism of Lipids] CTD PMID:15985485 NCBI chr13:86,377,679...86,385,523
Ensembl chr13:86,377,717...86,385,522 		JBrowse link
G Vdr vitamin D receptor increases abundance ISO VDR protein results in increased abundance of Norepinephrine CTD PMID:27450565 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression 		ISO [Cobalt co-treated with Norepinephrine] results in increased expression of VEGFA mRNA; [Cycloheximide co-treated with Norepinephrine] results in increased expression of VEGFA mRNA; [Norepinephrine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; AG 1879 inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA]; Cyclic AMP affects the reaction [Norepinephrine results in increased expression of VEGFA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Norepinephrine results in increased expression of VEGFA]; Propranolol inhibits the reaction [Norepinephrine results in increased expression of VEGFA mRNA] CTD PMID:10788502 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Xbp1 X-box binding protein 1 affects localization EXP Norepinephrine affects the localization of XBP1 protein CTD PMID:16338971 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xdh xanthine dehydrogenase increases expression EXP Norepinephrine results in increased expression of XDH mRNA CTD PMID:14618266 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
2-methoxyidazoxan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A affects binding
multiple interactions 		ISO ADRA2A protein binds to 2-methoxyidazoxan
Epinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; Norepinephrine inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; Oxymetazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]; xylometazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan] 		CTD PMID:20030735 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B affects binding
multiple interactions 		ISO ADRA2B protein binds to 2-methoxyidazoxan
Epinephrine inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan]; Norepinephrine inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan]; Oxymetazoline inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan]; xylometazoline inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] 		CTD PMID:20030735 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions
affects response to substance
affects binding 		ISO Epinephrine inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]; Norepinephrine inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]; Oxymetazoline inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]; xylometazoline inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan]
ADRA2C affects the susceptibility to 2-methoxyidazoxan 		CTD PMID:10336518 PMID:20030735 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP 2-methoxyidazoxan inhibits the reaction [Epinephrine results in increased expression of CCND1 protein] CTD PMID:17680988 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
adrenaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Serpinf1 serpin family F member 1 multiple interactions ISO epinephrine promotes the reaction [lipopolysaccharide increases expression of Serpinf1 protein in plasma] RGD PMID:9091588 RGD:11541073 NCBI chr10:60,748,504...60,760,898
Ensembl chr10:60,748,506...60,760,898 		JBrowse link
ajmalicine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression
multiple interactions 		ISO raubasine results in increased expression of CASP3 protein
CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein] 		CTD PMID:38064316 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions 		ISO raubasine results in decreased activity of CYP2D6 protein
raubasine inhibits the reaction [CYP2D6 protein affects the metabolism of Dextromethorphan] 		CTD PMID:15930738 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO raubasine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein] CTD PMID:29782822 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Gsdme gasdermin E increases cleavage ISO raubasine results in increased cleavage of GSDME protein CTD PMID:38064316 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
multiple interactions 		ISO raubasine results in increased expression of IL1B protein
raubasine results in increased secretion of IL1B protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of IL1B protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein] 		CTD PMID:38064316 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions 		ISO raubasine results in increased expression of IL6 protein
raubasine results in increased secretion of IL6 protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of IL6 protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein] 		CTD PMID:38064316 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression 		ISO raubasine results in increased secretion of TNF protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of TNF protein; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein]
raubasine results in increased expression of TNF protein 		CTD PMID:38064316 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
alfuzosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A affects binding
multiple interactions 		EXP
ISO 		alfuzosin binds to ADRA1A protein
alfuzosin inhibits the reaction [Prazosin binds to ADRA1A protein] 		CTD PMID:7536677 PMID:8183249 PMID:8196478 PMID:21544540 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B affects binding ISO alfuzosin binds to ADRA1B protein CTD PMID:8183249 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding ISO
EXP 		alfuzosin binds to ADRA1D protein CTD PMID:8183249 PMID:9294627 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP alfuzosin inhibits the reaction [Cyclophosphamide results in increased expression of FOS protein] CTD PMID:17240043 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP alfuzosin inhibits the reaction [Phenylephrine results in decreased secretion of GNRH1 protein]; alfuzosin inhibits the reaction [Phenylephrine results in increased secretion of GNRH1 protein] CTD PMID:1975657 NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP alfuzosin inhibits the reaction [Phenylephrine results in increased secretion of TAC1 protein] CTD PMID:17240043 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
alpha-methyl-L-dopa term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Comt catechol-O-methyltransferase increases methylation
decreases activity 		ISO COMT protein results in increased methylation of Methyldopa
Methyldopa results in decreased activity of COMT protein 		CTD PMID:7053299 PMID:11160877 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTA1 protein CTD PMID:8131222 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTM1 protein CTD PMID:8131222 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity ISO Methyldopa analog results in decreased activity of GSTP1 protein CTD PMID:8131222 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Prl prolactin increases expression
increases secretion 		ISO Methyldopa results in increased expression of PRL protein
Methyldopa results in increased secretion of PRL protein 		CTD PMID:1867878 PMID:7265421 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Ren renin decreases activity EXP Methyldopa results in decreased activity of REN protein CTD PMID:145319 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
apomorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amy2a3 amylase 2a3 multiple interactions EXP Apomorphine results in increased secretion of and results in increased activity of AMY1A protein; Atenolol inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein]; Metoclopramide inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:204,005,840...204,014,412
Ensembl chr 2:204,005,840...204,014,413 		JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions 		ISO Apomorphine results in increased expression of AVP protein
Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein] 		CTD PMID:16575035 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form] CTD PMID:25633564 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A decreases expression ISO Apomorphine results in decreased expression of BMPR1A mRNA CTD PMID:25633564 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861 		JBrowse link
G Cck cholecystokinin multiple interactions
decreases activity 		EXP Naloxone inhibits the reaction [CCK protein results in decreased activity of Apomorphine] CTD PMID:3561887 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:130,031,013...130,037,686 		JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance ISO CCKBR protein affects the susceptibility to Apomorphine CTD PMID:11702094 NCBI chr 1:169,183,578...169,193,583
Ensembl chr 1:169,183,194...169,193,745 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Apomorphine results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO Apomorphine binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole] 		CTD PMID:8103921 PMID:15985612 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects response to substance
increases response to substance 		ISO
EXP 		[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]
DRD2 protein affects the susceptibility to Apomorphine
DRD2 protein results in increased susceptibility to Apomorphine 		CTD PMID:2571179 PMID:7520908 PMID:8103596 PMID:8103921 PMID:14639100 More... NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Drd3 dopamine receptor D3 increases response to substance ISO DRD3 protein results in increased susceptibility to Apomorphine CTD PMID:19497322 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Apomorphine results in increased expression of FOS protein CTD PMID:10904129 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Apomorphine results in decreased expression of FURIN mRNA CTD PMID:25633564 NCBI chr 1:143,757,389...143,770,430
Ensembl chr 1:143,757,391...143,773,497 		JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP GDNF protein affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:58,621,327...58,647,240 		JBrowse link
G Gh1 growth hormone 1 increases secretion
increases expression 		ISO Apomorphine results in increased secretion of GH1 protein
Apomorphine results in increased expression of GH1 protein 		CTD PMID:993808 PMID:8889285 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases secretion
decreases expression 		ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Apomorphine results in decreased secretion of HAMP protein modified form
Apomorphine results in decreased expression of HAMP mRNA 		CTD PMID:25633564 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] CTD PMID:8539317 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases response to substance
multiple interactions 		EXP HTR6 protein results in increased susceptibility to Apomorphine
Ro4368554 inhibits the reaction [HTR6 protein results in increased susceptibility to Apomorphine] 		CTD PMID:17920665 NCBI chr 5:156,579,901...156,595,147
Ensembl chr 5:156,579,901...156,595,147 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Apomorphine inhibits the reaction [Oxidopamine results in increased phosphorylation of JUN protein] CTD PMID:14599342 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO Apomorphine results in increased activity of ODC1 protein CTD PMID:10354516 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Penk proenkephalin multiple interactions EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] CTD PMID:17719177 NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:21,981,382...21,986,705 		JBrowse link
G Prl prolactin decreases expression ISO Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Pvalb parvalbumin affects expression EXP Apomorphine affects the expression of PVALB protein CTD PMID:15238432 NCBI chr 7:111,653,820...111,668,469
Ensembl chr 7:111,653,111...111,668,446 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Apomorphine CTD PMID:15728856 NCBI chr10:94,696,556...94,770,387
Ensembl chr10:94,696,556...94,770,387 		JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions EXP SHH protein modified form affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Sst somatostatin affects secretion EXP Apomorphine affects the secretion of SST protein CTD PMID:17961553 NCBI chr11:90,461,546...90,462,823
Ensembl chr11:90,461,546...90,462,823 		JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:216,456,148...216,518,718
Ensembl chr 1:216,456,259...216,518,718 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:17719177 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
asenapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases expression 		ISO Asenapine results in decreased activity of CYP1A2 protein
Asenapine results in decreased expression of CYP1A2 mRNA 		CTD PMID:32941854 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
brimonidine tartrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP 		Brimonidine Tartrate inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]; Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:8397342 PMID:10742289 PMID:12208771 PMID:12598592 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Agt angiotensinogen multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased abundance of Superoxides]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Brimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation EXP Brimonidine Tartrate results in increased phosphorylation of CREB1 protein CTD PMID:17680988 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Prkca protein kinase C, alpha affects localization
multiple interactions 		EXP Brimonidine Tartrate affects the localization of PRKCA protein
Nitric Oxide deficiency promotes the reaction [Brimonidine Tartrate affects the localization of PRKCA protein] 		CTD PMID:12388232 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta affects localization
multiple interactions 		EXP Brimonidine Tartrate affects the localization of PRKCD protein
Nitric Oxide deficiency inhibits the reaction [Brimonidine Tartrate affects the localization of PRKCD protein] 		CTD PMID:12388232 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Rhoa ras homolog family member A multiple interactions EXP 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; bisindolylmaleimide I inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; Brimonidine Tartrate promotes the reaction [AGT protein results in increased activity of RHOA protein]; diphenyleneiodonium inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]]; tempol inhibits the reaction [Brimonidine Tartrate promotes the reaction [AGT protein results in increased expression of RHOA protein]] CTD PMID:18250367 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Brimonidine Tartrate inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
carvedilol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression 		ISO Carvedilol inhibits the reaction [Albuterol results in increased expression of ABCB11 mRNA]
Carvedilol results in decreased expression of ABCB11 protein 		CTD PMID:37632784 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
decreases activity 		ISO
EXP 		ABCB1 protein results in increased transport of carvedilol
[Cyclosporine results in decreased activity of ABCB1 protein] which results in increased uptake of carvedilol
[carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]] which results in decreased susceptibility to Daunorubicin; [carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]] which results in decreased susceptibility to Doxorubicin; [carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]] which results in decreased susceptibility to Paclitaxel; [carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine; [carvedilol results in decreased activity of ABCB1 protein] which results in increased susceptibility to Doxorubicin; [carvedilol results in decreased activity of ABCB1 protein] which results in increased uptake of fluorexon; carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Doxorubicin]; carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Paclitaxel]; carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; valspodar inhibits the reaction [ABCB1 protein results in increased transport of carvedilol] 		CTD PMID:10571255 PMID:11895100 PMID:12708479 PMID:16671962 PMID:17609666 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO Carvedilol results in decreased expression of ABCC2 protein CTD PMID:37632784 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO Carvedilol results in decreased expression of ABCC4 protein CTD PMID:37632784 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP
ISO 		carvedilol inhibits the reaction [Colchicine results in decreased activity of ACE protein]
carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA] 		CTD PMID:15071347 PMID:18992766 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression 		EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; Carvedilol inhibits the reaction [Ethanol results in increased expression of ACTA2 mRNA]; Carvedilol inhibits the reaction [Ethanol results in increased expression of ACTA2 protein]
carvedilol results in decreased expression of ACTA2 protein 		CTD PMID:20403466 PMID:22413959 PMID:30254303 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP carvedilol results in decreased expression of ACTN4 protein CTD PMID:20403466 NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO carvedilol results in decreased expression of ADIPOQ protein CTD PMID:19367012 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
decreases expression 		ISO
EXP 		Carvedilol binds to and results in decreased activity of ADRA1A protein; Carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
carvedilol results in decreased expression of ADRA1A mRNA 		CTD PMID:15306222 PMID:20668454 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO carvedilol binds to and results in decreased activity of ADRA1B protein; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions ISO carvedilol binds to and results in decreased activity of ADRA1D protein; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects binding
increases expression
increases phosphorylation
increases activity
affects response to substance 		ISO
EXP 		[ADRB1 gene co-treated with ADRB2 gene] affects the susceptibility to Carvedilol; [Carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP; [Carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP; ADRB1 protein polymorphism affects the reaction [[Carvedilol binds to and results in decreased activity of ADRB1 protein] which results in decreased abundance of Cyclic AMP]; ADRB1 protein polymorphism affects the susceptibility to [Carvedilol co-treated with Angiotensin Receptor Antagonists]; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Carvedilol binds to and results in decreased activity of ADRB1 protein; Carvedilol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]; Carvedilol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Carvedilol inhibits the reaction [cyanopindolol binds to ADRB1 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased activity of ADRB1 protein]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; Carvedilol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; CGP 20712A inhibits the reaction [[Carvedilol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [Carvedilol results in increased activity of ADRB1 protein]; Guanine Nucleotides affects the reaction [Carvedilol binds to ADRB1 protein]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
carvedilol binds to ADRB1 protein
carvedilol results in increased expression of ADRB1 mRNA
carvedilol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; carvedilol inhibits the reaction [Dihydroalprenolol binds to ADRB1 protein]
[carvedilol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein; carvedilol results in increased phosphorylation of ADRB1 protein
carvedilol results in increased activity of ADRB1 protein
ADRB1 gene polymorphism affects the susceptibility to carvedilol; ADRB1 protein polymorphism affects the susceptibility to carvedilol 		CTD PMID:1378154 PMID:2462161 PMID:7908256 PMID:10372227 PMID:12535855 More... NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions
increases phosphorylation
affects binding
increases expression
increases uptake
affects response to substance 		ISO
EXP 		[ADRB1 gene co-treated with ADRB2 gene] affects the susceptibility to carvedilol; [carvedilol binds to ADRB2 protein] which results in decreased abundance of Cyclic AMP; [carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; [carvedilol binds to and results in decreased activity of ADRB2 protein] which results in decreased abundance of Cyclic AMP; [carvedilol co-treated with ADRB2 protein] results in increased expression of GNAS protein; [carvedilol co-treated with ADRB2 protein] results in increased expression of GRK2 protein; carvedilol binds to and results in decreased activity of ADRB2 protein; carvedilol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; carvedilol inhibits the reaction [cyanopindolol binds to ADRB2 protein]; carvedilol inhibits the reaction [Epinephrine binds to and results in increased activity of ADRB2 protein]; carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; Guanine Nucleotides affects the reaction [carvedilol binds to ADRB2 protein]; ICI 118551 inhibits the reaction [[carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein]; ICI 118551 inhibits the reaction [[carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein]; ICI 118551 inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol results in increased phosphorylation of ADRB2 protein]
carvedilol results in increased expression of ADRB2 mRNA
carvedilol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; carvedilol inhibits the reaction [Dihydroalprenolol binds to ADRB2 protein]
carvedilol inhibits the reaction [ADRB2 results in decreased susceptibility to Histamine]; carvedilol inhibits the reaction [ADRB2 results in increased expression of GRK2 protein]
carvedilol results in increased uptake of ADRB2 protein
ADRB2 gene SNP affects the susceptibility to carvedilol; ADRB2 protein polymorphism affects the susceptibility to carvedilol 		CTD PMID:1378154 PMID:2462161 PMID:10372227 PMID:10455254 PMID:12198331 More... NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
decreases expression
affects response to substance 		ISO
EXP 		carvedilol inhibits the reaction [cyanopindolol binds to ADRB3 protein]
carvedilol results in decreased expression of ADRB3 mRNA
ADRB3 affects the susceptibility to carvedilol 		CTD PMID:11159692 PMID:14730417 PMID:17440824 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Agt angiotensinogen multiple interactions
decreases response to substance
decreases expression 		EXP
ISO 		[Losartan co-treated with Carvedilol] results in decreased susceptibility to AGT protein modified form; Carvedilol inhibits the reaction [AGT protein affects the localization of RAC1 protein]; Carvedilol inhibits the reaction [AGT protein results in increased abundance of Glycerol]; Carvedilol inhibits the reaction [AGT protein results in increased abundance of Norepinephrine]; Carvedilol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species]; Carvedilol inhibits the reaction [Losartan results in decreased susceptibility to AGT protein modified form]; Losartan inhibits the reaction [Carvedilol results in decreased susceptibility to AGT protein modified form]
carvedilol results in decreased susceptibility to AGT protein modified form
carvedilol inhibits the reaction [AGT protein modified form promotes the reaction [Phenylephrine results in increased abundance of Inositol Phosphates]]; carvedilol inhibits the reaction [AGT protein modified form results in increased susceptibility to Phenylephrine]
carvedilol results in decreased expression of AGT protein 		CTD PMID:12004934 PMID:12538430 PMID:15741261 PMID:16794485 PMID:16940222 More... NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation EXP
ISO 		carvedilol results in increased phosphorylation of AKT1 protein CTD PMID:27288437 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G App amyloid beta precursor protein decreases expression ISO carvedilol results in decreased expression of APP protein modified form CTD PMID:20579773 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971 		JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR125A mRNA; [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR125B-1 mRNA; [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR150 mRNA; [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA; [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR214 mRNA; ARRB1 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; carvedilol promotes the reaction [ADRB1 protein binds to ARRB1 protein]; carvedilol promotes the reaction [ARRB1 protein binds to DROSHA protein]; carvedilol promotes the reaction [ARRB1 protein binds to HNRNPA1 protein]; Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; GRK5 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; GRK6 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; Metoprolol inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]
ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125A mRNA]; ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR150 mRNA]; ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR214 mRNA]; carvedilol promotes the reaction [ARRB1 protein binds to DROSHA protein]; carvedilol promotes the reaction [ARRB1 protein binds to HNRNPA1 protein] 		CTD PMID:18787115 PMID:24334028 NCBI chr 1:163,249,654...163,321,711
Ensembl chr 1:163,250,157...163,340,859 		JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions
affects localization 		ISO
EXP 		ARRB2 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [carvedilol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [carvedilol results in increased phosphorylation of MAPK3 protein]; carvedilol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; ICI 118551 inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
carvedilol affects the localization of ARRB2 protein 		CTD PMID:17925438 PMID:18787115 PMID:21078978 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,645,357...55,653,487 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
increases expression 		EXP carvedilol inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP2A2 mRNA]; carvedilol inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP2A2 protein]
carvedilol results in increased expression of ATP2A2 mRNA 		CTD PMID:15670758 PMID:16026515 PMID:16162791 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Avp arginine vasopressin decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of AVP protein
carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] 		CTD PMID:12523682 PMID:14711191 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Carvedilol] which results in decreased expression of BAK1 mRNA CTD PMID:29122578 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
decreases expression 		EXP
ISO 		carvedilol inhibits the reaction [Doxorubicin results in increased expression of BAX mRNA]; carvedilol inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]
carvedilol inhibits the reaction [Cisplatin results in increased expression of BAX protein]
carvedilol results in increased expression of BAX protein
carvedilol results in decreased expression of BAX 		CTD PMID:12973927 PMID:15380674 PMID:20079142 PMID:24012798 PMID:25245570 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
affects expression 		EXP carvedilol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]; carvedilol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; carvedilol inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]
carvedilol results in increased expression of BCL2 mRNA
carvedilol affects the expression of BCL2 protein 		CTD PMID:15380674 PMID:16780994 PMID:16909474 PMID:22000973 PMID:25245570 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP carvedilol results in increased expression of BCL2L1 protein CTD PMID:20079142 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Becn1 beclin 1 increases expression EXP carvedilol results in increased expression of BECN1 protein CTD PMID:20079142 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP capsazepine inhibits the reaction [carvedilol results in increased secretion of [CALCA protein co-treated with CALCB protein]]; carvedilol results in increased secretion of [CALCA protein co-treated with CALCB protein] CTD PMID:14764656 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Calcb calcitonin-related polypeptide, beta multiple interactions EXP capsazepine inhibits the reaction [carvedilol results in increased secretion of [CALCA protein co-treated with CALCB protein]]; carvedilol results in increased secretion of [CALCA protein co-treated with CALCB protein] CTD PMID:14764656 NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CAMK2D protein] CTD PMID:26982530 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO 		[Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]
carvedilol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein]
carvedilol inhibits the reaction [Epinephrine results in increased activity of CASP3 protein] 		CTD PMID:10728402 PMID:15380674 PMID:21044617 PMID:24012798 PMID:25245570 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase multiple interactions
increases activity 		EXP Carvedilol inhibits the reaction [Arginine results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Aspirin results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Chlorpromazine results in decreased expression of CAT protein]; Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of CAT protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]
carvedilol results in increased activity of CAT protein 		CTD PMID:12010767 PMID:16909474 PMID:25245570 PMID:25496245 PMID:32295429 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in decreased expression of CDH1 protein] CTD PMID:30254303 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Cfl1 cofilin 1 decreases expression EXP carvedilol results in decreased expression of CFL1 protein CTD PMID:20403466 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353 		JBrowse link
G Ckb creatine kinase B multiple interactions EXP Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]] CTD PMID:25496245 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478 		JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of [CKM protein binds to CKB protein]]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of CKM protein] CTD PMID:25496245 PMID:26982530 NCBI chr 1:88,189,382...88,199,717
Ensembl chr 1:88,189,485...88,199,719 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
decreases expression 		EXP carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL1A1 mRNA]; carvedilol inhibits the reaction [Ethanol results in increased expression of COL1A1 mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA]
carvedilol decreases expression of collagen I mRNA in kidney of high fat high sodium diet fed SHRSP/A3N rats
Carvedilol results in decreased expression of COL1A1 mRNA; Carvedilol results in decreased expression of COL1A1 protein 		CTD
RGD		 PMID:10722803 PMID:11181017 PMID:11682445 PMID:19575289 PMID:21216836 More... RGD:30296650 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
decreases expression 		EXP carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of COL3A1 mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased expression of COL3A1 mRNA]
carvedilol decreases expression of collagen III mRNA in kidney of high fat high sodium diet fed SHRSP/A3N rats
carvedilol results in decreased expression of COL3A1 protein 		CTD
RGD		 PMID:10722803 PMID:11181017 PMID:11682445 PMID:11682445 RGD:30296650 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Crp C-reactive protein decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of CRP protein
Carvedilol inhibits the reaction [Arginine results in increased expression of CRP protein] 		CTD PMID:15047035 PMID:32569593 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO carvedilol inhibits the reaction [CSF2 results in increased expression of IL10 mRNA]; carvedilol inhibits the reaction [CSF2 results in increased expression of IL10 protein] CTD PMID:12722941 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031 		JBrowse link
G Cycs cytochrome c, somatic increases expression EXP carvedilol results in increased expression of CYCS protein CTD PMID:18971572 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Carvedilol results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Carvedilol results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases metabolic processing EXP CYP2C11 protein results in increased metabolism of carvedilol CTD PMID:29415952 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 increases metabolic processing EXP CYP2D2 protein results in increased metabolism of carvedilol CTD PMID:29415952 NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects glucuronidation
affects metabolic processing
affects response to substance 		ISO CYP2D6 gene polymorphism affects the glucuronidation of carvedilol
CYP2D6 gene polymorphism affects the metabolism of carvedilol; CYP2D6 protein polymorphism affects the metabolism of carvedilol
CYP2D6 gene polymorphism affects the susceptibility to carvedilol 		CTD PMID:15001973 PMID:16595916 PMID:16849011 PMID:17329852 PMID:20643254 More... NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing EXP CYP3A2 protein results in increased metabolism of carvedilol CTD PMID:29415952 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases metabolic processing EXP CYP3A23-3A1 protein results in increased metabolism of Carvedilol CTD PMID:29415952 NCBI chr12:14,369,950...14,398,803
Ensembl chr12:14,368,266...14,398,813 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO Carvedilol results in increased expression of CYP7A1 protein CTD PMID:37632784 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression ISO carvedilol results in decreased expression of DDIT4 mRNA CTD PMID:27288437 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037 		JBrowse link
G Drosha drosha ribonuclease III multiple interactions ISO carvedilol promotes the reaction [ARRB1 protein binds to DROSHA protein] CTD PMID:24334028 NCBI chr 2:63,591,885...63,703,688
Ensembl chr 2:63,591,968...63,703,687 		JBrowse link
G Edn1 endothelin 1 decreases secretion
decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased secretion of EDN1 protein
carvedilol results in decreased expression of EDN1 mRNA
carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]
carvedilol results in decreased expression of EDN1 mRNA; carvedilol results in decreased expression of EDN1 protein
carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 protein] 		CTD PMID:9500873 PMID:11078433 PMID:14711191 PMID:16428915 PMID:18971572 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation 		ISO AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of and results in increased uptake of EGFR protein]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]; Propranolol inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]]
[carvedilol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein 		CTD PMID:18787115 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions EXP [irbesartan co-treated with carvedilol] results in decreased expression of F3 mRNA; [irbesartan co-treated with carvedilol] results in decreased expression of F3 protein CTD PMID:21229253 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO carvedilol inhibits the reaction [Epinephrine results in increased expression of FAS protein] CTD PMID:10728402 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Faslg Fas ligand multiple interactions ISO carvedilol inhibits the reaction [Epinephrine results in increased expression of FASLG protein] CTD PMID:10728402 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fasn fatty acid synthase multiple interactions EXP carvedilol inhibits the reaction [Ethanol results in increased expression of FASN mRNA] CTD PMID:22413959 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO carvedilol promotes the reaction [FKBP1B protein binds to RYR2 protein] CTD PMID:12743001 NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:33,558,517...33,568,129 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
decreases expression 		EXP carvedilol inhibits the reaction [[Sodium, Dietary co-treated with Dietary Fats] results in increased expression of FN1 mRNA]; carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]
carvedilol decreases expression of fibronectin mRNA in kidney of high fat high sodium diet fed SHRSP/A3N rats
carvedilol results in decreased expression of FN1 protein 		CTD
RGD		 PMID:11181017 PMID:11682445 PMID:12140129 PMID:11682445 RGD:30296650 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Gap43 growth associated protein 43 decreases expression EXP carvedilol results in decreased expression of GAP43 mRNA; carvedilol results in decreased expression of GAP43 protein CTD PMID:20359859 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Gata4 GATA binding protein 4 decreases phosphorylation EXP carvedilol results in decreased phosphorylation of GATA4 protein CTD PMID:21472269 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
affects localization
decreases phosphorylation
increases phosphorylation
decreases degradation 		ISO
EXP 		carvedilol results in increased expression of GJA1 mRNA; carvedilol results in increased expression of GJA1 protein
carvedilol affects the localization of GJA1 protein
carvedilol results in decreased phosphorylation of GJA1 protein
carvedilol results in increased phosphorylation of GJA1 protein
carvedilol results in decreased degradation of GJA1 protein 		CTD PMID:16448880 PMID:16563290 PMID:17445419 PMID:18971572 PMID:19478468 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gja4 gap junction protein, alpha 4 increases expression EXP carvedilol results in increased expression of GJA4 protein CTD PMID:16448880 NCBI chr 5:144,917,791...144,920,324
Ensembl chr 5:144,914,147...144,921,216 		JBrowse link
G Gnas GNAS complex locus multiple interactions
increases expression 		ISO
EXP 		[carvedilol co-treated with ADRB2 protein] results in increased expression of GNAS protein
carvedilol results in increased expression of GNAS mRNA 		CTD PMID:10455254 PMID:20668454 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GOT1 protein] CTD PMID:25496245 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gpnmb glycoprotein nmb decreases expression EXP carvedilol results in decreased expression of GPNMB protein CTD PMID:20403466 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of GPT protein] CTD PMID:25496245 PMID:30254303 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions
decreases expression
increases expression 		ISO [carvedilol co-treated with ADRB2 protein] results in increased expression of GRK2 protein
carvedilol results in decreased expression of GRK2 protein
carvedilol results in increased expression of GRK2 protein
carvedilol inhibits the reaction [ADRB2 results in increased expression of GRK2 protein] 		CTD PMID:9788834 PMID:10455254 PMID:12198331 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Grk5 G protein-coupled receptor kinase 5 multiple interactions ISO GRK5 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]
GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125A mRNA]; GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR150 mRNA]; GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR214 mRNA] 		CTD PMID:24334028 NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 multiple interactions ISO GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR125A mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR125B-1 mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR150 mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR214 mRNA]
GRK6 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] 		CTD PMID:24334028 NCBI chr17:9,182,160...9,198,380
Ensembl chr17:9,182,160...9,197,954 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO HBEGF protein inhibits the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; HBEGF protein inhibits the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; HBEGF protein promotes the reaction [carvedilol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] CTD PMID:18787115 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO carvedilol results in increased expression of HMOX1 mRNA CTD PMID:11688356 PMID:12227681 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions ISO carvedilol promotes the reaction [ARRB1 protein binds to HNRNPA1 protein] CTD PMID:24334028 NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085 		JBrowse link
G Hpca hippocalcin affects localization EXP carvedilol affects the localization of HPCA protein CTD PMID:21078978 NCBI chr 5:146,739,978...146,750,961
Ensembl chr 5:146,739,978...146,749,983 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP carvedilol results in increased expression of HSPH1 protein CTD PMID:20403466 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Ifng interferon gamma multiple interactions ISO carvedilol inhibits the reaction [Hemagglutinins results in increased expression of IFNG protein] CTD PMID:15229385 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions EXP carvedilol inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] CTD PMID:26036690 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression 		ISO
EXP 		carvedilol inhibits the reaction [CSF2 results in increased expression of IL10 mRNA]; carvedilol inhibits the reaction [CSF2 results in increased expression of IL10 protein]
carvedilol results in increased expression of IL10 mRNA; carvedilol results in increased expression of IL10 protein 		CTD PMID:12722941 PMID:16310260 PMID:18971572 PMID:20017808 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il12a interleukin 12A multiple interactions ISO carvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]]; carvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15229385 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO carvedilol promotes the reaction [Hemagglutinins results in increased expression of [IL12A protein binds to IL12B protein]]; carvedilol promotes the reaction [Lipopolysaccharides results in increased expression of [IL12A protein binds to IL12B protein]] CTD PMID:15229385 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194 		JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of IL1B mRNA
carvedilol results in decreased expression of IL1B mRNA; carvedilol results in decreased expression of IL1B protein
Carvedilol inhibits the reaction [Arginine results in increased expression of IL1B protein]; Carvedilol inhibits the reaction [Aspirin results in increased expression of IL1B protein]; Carvedilol inhibits the reaction [Norepinephrine results in increased expression of IL1B mRNA]
carvedilol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] 		CTD PMID:10722803 PMID:14684360 PMID:15921778 PMID:16310260 PMID:20017808 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression EXP carvedilol results in increased expression of IL1RN protein CTD PMID:20017808 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions 		EXP carvedilol results in decreased expression of IL6 mRNA; carvedilol results in decreased expression of IL6 protein
Carvedilol inhibits the reaction [Aspirin results in increased expression of IL6 protein]; Carvedilol inhibits the reaction [Norepinephrine results in increased expression of IL6 mRNA] 		CTD PMID:10722803 PMID:11406463 PMID:16310260 PMID:32295429 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ins2 insulin 2 decreases expression ISO carvedilol results in decreased expression of INS protein alternative form CTD PMID:16598518 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Jph2 junctophilin 2 increases expression ISO carvedilol results in increased expression of JPH2 protein CTD PMID:22375019 NCBI chr 3:172,414,246...172,478,678
Ensembl chr 3:172,414,256...172,478,348 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 multiple interactions EXP carvedilol binds to and results in decreased activity of KCNA5 protein CTD PMID:22146582 NCBI chr 4:161,040,853...161,044,311
Ensembl chr 4:160,996,950...161,044,408 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
affects activity 		ISO carvedilol results in decreased activity of KCNH2 protein
carvedilol affects the activity of KCNH2 protein 		CTD PMID:11164846 PMID:16314852 PMID:22020101 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 decreases activity ISO carvedilol results in decreased activity of KCNJ11 protein CTD PMID:16325804 NCBI chr 1:105,727,473...105,731,167
Ensembl chr 1:105,727,570...105,731,169 		JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 multiple interactions ISO carvedilol binds to and results in decreased activity of KCNJ4 protein; Phosphatidylinositol Phosphates inhibits the reaction [carvedilol binds to and results in decreased activity of KCNJ4 protein] CTD PMID:21663737 NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:112,922,532...112,954,826 		JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 decreases activity ISO carvedilol results in decreased activity of KCNK3 protein CTD PMID:21410455 NCBI chr 6:31,483,129...31,519,061
Ensembl chr 6:31,483,140...31,519,061 		JBrowse link
G Klf13 KLF transcription factor 13 multiple interactions EXP [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Carvedilol] which results in decreased expression of KLF13 mRNA CTD PMID:29122578 NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:126,916,781...126,961,056 		JBrowse link
G Lox lysyl oxidase decreases expression EXP carvedilol results in decreased expression of LOX mRNA CTD PMID:21216836 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation 		EXP
ISO 		[Doxorubicin co-treated with carvedilol] results in increased phosphorylation of MAPK1 protein; carvedilol inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK1 protein]
Erlotinib Hydrochloride inhibits the reaction [carvedilol results in increased phosphorylation of MAPK1 protein]
[Carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [Carvedilol results in increased phosphorylation of MAPK1 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ICI 118551 inhibits the reaction [[Carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] 		CTD PMID:11054474 PMID:15306222 PMID:16213474 PMID:17925438 PMID:18787115 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP carvedilol inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK14 protein] CTD PMID:16213474 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation 		EXP
ISO 		[Doxorubicin co-treated with carvedilol] results in increased phosphorylation of MAPK3 protein; carvedilol inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK3 protein]
carvedilol results in increased phosphorylation of MAPK3 protein
Erlotinib Hydrochloride inhibits the reaction [carvedilol results in increased phosphorylation of MAPK3 protein]
[Carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein; AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB1 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [Carvedilol results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]; HBEGF protein inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ICI 118551 inhibits the reaction [[Carvedilol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; RTKI cpd inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]] 		CTD PMID:11054474 PMID:15306222 PMID:16213474 PMID:17925438 PMID:18787115 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing decreases expression EXP carvedilol results in decreased expression of MFGE8 protein CTD PMID:20403466 NCBI chr 1:142,474,027...142,489,431
Ensembl chr 1:142,474,028...142,489,431 		JBrowse link
G Mir125a microRNA 125a multiple interactions
increases expression 		ISO [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR125A mRNA
ARRB1 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR125A mRNA]; GRK5 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR125A mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR125A mRNA]
carvedilol results in increased expression of MIR125A mRNA 		CTD PMID:24334028 NCBI chr 1:67,350,675...67,350,759
Ensembl chr 1:67,350,675...67,350,759 		JBrowse link
G Mir125b1 microRNA 125b-1 multiple interactions
increases expression 		ISO ARRB1 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; GRK5 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]; GRK6 gene mutant form inhibits the reaction [carvedilol results in increased expression of MIR125B-1 mRNA]
[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR125B-1 mRNA 		CTD PMID:24334028 NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:50,850,036...50,850,122 		JBrowse link
G Mir125b2 microRNA 125b-2 increases expression ISO Carvedilol results in increased expression of MIR125B2 mRNA CTD PMID:29122578 NCBI chr11:29,732,572...29,732,659 JBrowse link
G Mir150 microRNA 150 multiple interactions
increases expression 		ISO [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR150 mRNA
ARRB1 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR150 mRNA]; GRK5 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR150 mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR150 mRNA] 		CTD PMID:24334028 NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571 		JBrowse link
G Mir190a microRNA 190a multiple interactions ISO [carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA; Colforsin inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; GRK5 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; GRK6 mutant form inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA]; Metoprolol inhibits the reaction [[carvedilol co-treated with ARRB1 protein] results in increased expression of MIR190A mRNA] CTD PMID:24334028 NCBI chr 8:76,732,179...76,732,263 JBrowse link
G Mir200a microRNA 200a multiple interactions EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in decreased expression of MIR200A mRNA] CTD PMID:30254303 NCBI chr 5:171,930,717...171,930,805 JBrowse link
G Mir214 microRNA 214 multiple interactions
increases expression 		ISO ARRB1 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR214 mRNA]; GRK5 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR214 mRNA]; GRK6 gene mutant form inhibits the reaction [Carvedilol results in increased expression of MIR214 mRNA]
[Carvedilol co-treated with ARRB1 protein] results in increased expression of MIR214 mRNA 		CTD PMID:24334028 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases activity
decreases expression 		EXP
ISO 		carvedilol inhibits the reaction [Doxorubicin results in increased expression of MMP2 mRNA]
carvedilol results in decreased activity of MMP2 protein
carvedilol inhibits the reaction [TNF protein results in increased expression of MMP2 protein]
carvedilol results in decreased expression of MMP2 		CTD PMID:16213474 PMID:16310260 PMID:17964422 PMID:20452391 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp8 matrix metallopeptidase 8 decreases expression ISO carvedilol results in decreased expression of MMP8 mRNA CTD PMID:15921778 NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:13,008,890...13,018,729 		JBrowse link
G Mmp9 matrix metallopeptidase 9 affects activity
decreases expression
decreases activity
multiple interactions 		ISO
EXP 		carvedilol affects the activity of MMP9 protein
carvedilol results in decreased expression of MMP9 mRNA
carvedilol results in decreased activity of MMP9 protein
carvedilol inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
carvedilol inhibits the reaction [Doxorubicin results in increased expression of MMP9 mRNA] 		CTD PMID:16213474 PMID:16310260 PMID:16574429 PMID:17964422 PMID:18971572 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO
EXP 		carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased expression of MPO protein]
Carvedilol inhibits the reaction [Arginine results in increased expression of MPO protein]
carvedilol inhibits the reaction [Calcimycin results in increased secretion of MPO protein]; carvedilol inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of MPO protein]; carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein] 		CTD PMID:16601795 PMID:17159805 PMID:18987595 PMID:32569593 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Msn moesin decreases expression EXP carvedilol results in decreased expression of MSN protein CTD PMID:20403466 NCBI chr  X:65,005,546...65,073,512
Ensembl chr  X:65,005,458...65,075,129 		JBrowse link
G Mstn myostatin decreases expression EXP carvedilol results in decreased expression of MSTN mRNA; carvedilol results in decreased expression of MSTN protein CTD PMID:16968467 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:55,944,513...55,950,913 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
affects expression 		EXP carvedilol results in decreased expression of MYC protein
carvedilol affects the expression of MYC protein 		CTD PMID:21472269 PMID:22000973 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Myl12a myosin light chain 12A decreases expression EXP carvedilol results in decreased expression of MYL12A protein CTD PMID:20403466 NCBI chr 9:118,338,592...118,346,277
Ensembl chr 9:118,338,604...118,342,634 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases phosphorylation EXP carvedilol results in increased phosphorylation of NFATC4 protein CTD PMID:21472269 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP 		Atenolol inhibits the reaction [carvedilol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Atenolol inhibits the reaction [carvedilol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; carvedilol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; carvedilol inhibits the reaction [Dopamine inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; carvedilol inhibits the reaction [Dopamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; carvedilol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; carvedilol promotes the reaction [wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Prazosin inhibits the reaction [carvedilol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]]; Prazosin inhibits the reaction [carvedilol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]
Carvedilol inhibits the reaction [Aspirin results in increased expression of NOS2 protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of NOS2 protein] 		CTD PMID:17159805 PMID:19439816 PMID:25245570 PMID:32295429 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
increases phosphorylation
decreases expression 		EXP
ISO 		carvedilol results in increased expression of NOS3 mRNA; carvedilol results in increased expression of NOS3 protein
Carvedilol inhibits the reaction [Doxorubicin results in decreased phosphorylation of NOS3 protein]
carvedilol results in increased phosphorylation of NOS3 protein
carvedilol results in decreased expression of NOS3 mRNA 		CTD PMID:16741616 PMID:17559835 PMID:18971572 PMID:31066085 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP carvedilol inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA] CTD PMID:16213474 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520 		JBrowse link
G Nphs1 NPHS1 adhesion molecule, nephrin increases expression EXP Carvedilol results in increased expression of NPHS1 CTD PMID:20452391 NCBI chr 1:94,848,261...94,876,522
Ensembl chr 1:94,848,261...94,876,521 		JBrowse link
G Nppa natriuretic peptide A decreases expression
increases expression
decreases degradation
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of NPPA protein
carvedilol results in increased expression of NPPA mRNA; carvedilol results in increased expression of NPPA protein
carvedilol results in decreased expression of NPPA mRNA
carvedilol results in decreased degradation of NPPA protein
carvedilol inhibits the reaction [Norepinephrine results in increased expression of NPPA mRNA]; carvedilol promotes the reaction [NPPA protein results in increased abundance of Cyclic GMP] 		CTD PMID:1378157 PMID:9421401 PMID:10722803 PMID:11206715 PMID:21216836 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B multiple interactions
decreases expression
increases expression 		ISO
EXP 		[carvedilol co-treated with temocapril hydrochloride co-treated with Spironolactone co-treated with Aspirin] affects the expression of NPPB protein
carvedilol inhibits the reaction [Doxorubicin results in increased expression of NPPB protein]
carvedilol results in decreased expression of NPPB protein
carvedilol results in decreased expression of NPPB mRNA; carvedilol results in decreased expression of NPPB protein
carvedilol results in increased expression of NPPB mRNA 		CTD PMID:11206715 PMID:19367012 PMID:19650993 PMID:19692266 PMID:20413026 More... NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Npr3 natriuretic peptide receptor 3 decreases expression EXP carvedilol results in decreased expression of NPR3 mRNA CTD PMID:9421401 PMID:11206715 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:62,597,668...62,660,066 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Carvedilol results in decreased expression of NR0B2 mRNA CTD PMID:37632784 NCBI chr 5:151,063,160...151,066,475
Ensembl chr 5:151,063,160...151,066,475 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression ISO Carvedilol results in increased expression of NR1H4 mRNA CTD PMID:37632784 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions EXP carvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]; carvedilol inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]; carvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]; carvedilol inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein] CTD PMID:16055083 NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO carvedilol results in decreased susceptibility to [PDGFB protein binds to PDGFB protein] CTD PMID:11904532 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343 		JBrowse link
G Pgd phosphogluconate dehydrogenase multiple interactions EXP carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased activity of PGD protein] CTD PMID:1378361 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP carvedilol inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:22413959 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression EXP carvedilol results in increased expression of PPARGC1A mRNA CTD PMID:18971572 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213 		JBrowse link
G Prkca protein kinase C, alpha decreases expression EXP carvedilol results in decreased expression of PRKCA protein CTD PMID:20668454 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Prkcd protein kinase C, delta decreases expression EXP carvedilol results in decreased expression of PRKCD protein CTD PMID:20668454 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Prkce protein kinase C, epsilon increases activity EXP carvedilol results in increased activity of PRKCE protein CTD PMID:16782078 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions EXP Carvedilol inhibits the reaction [Arginine results in increased expression of PTAFR mRNA] CTD PMID:32569593 NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression EXP carvedilol results in decreased expression of PTGS1 mRNA CTD PMID:16741616 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Carvedilol inhibits the reaction [Aspirin results in increased expression of PTGS2 protein] CTD PMID:32295429 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP carvedilol inhibits the reaction [AGT protein affects the localization of RAC1 protein] CTD PMID:16940222 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109 		JBrowse link
G Reg3b regenerating family member 3 beta multiple interactions EXP Carvedilol inhibits the reaction [Arginine results in increased expression of REG3B mRNA] CTD PMID:32569593 NCBI chr 4:112,419,776...112,423,014
Ensembl chr 4:112,419,776...112,423,014 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Carvedilol inhibits the reaction [Arginine results in increased expression of RELA protein]; Carvedilol inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of RELA protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Carvedilol inhibits the reaction [Potassium Dichromate affects the localization of RELA protein] CTD PMID:25245570 PMID:26036690 PMID:30254303 PMID:32569593 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of REN protein
[aliskiren co-treated with Carvedilol] inhibits the reaction [Isoproterenol results in increased activity of REN protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased activity of REN protein] 		CTD PMID:2454358 PMID:26982530 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Ryr2 ryanodine receptor 2 affects activity
decreases activity
increases expression
multiple interactions
increases activity 		ISO
EXP 		carvedilol affects the activity of RYR2 protein; carvedilol analog affects the activity of RYR2 protein
Carvedilol results in decreased activity of RYR2 protein
carvedilol results in increased expression of RYR2 protein
[Huang Qi co-treated with carvedilol] results in increased expression of RYR2 mRNA
carvedilol promotes the reaction [Perindopril results in increased expression of RYR2 protein]; Perindopril promotes the reaction [carvedilol results in increased expression of RYR2 protein]
carvedilol results in increased expression of RYR2 mRNA
carvedilol results in increased activity of RYR2 protein
carvedilol inhibits the reaction [Isoproterenol results in increased phosphorylation of RYR2 protein]; carvedilol promotes the reaction [FKBP1B protein binds to RYR2 protein] 		CTD PMID:12743001 PMID:19620082 PMID:21743453 PMID:21924056 PMID:37850394 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:63,081,527...63,666,705 		JBrowse link
G S100a10 S100 calcium binding protein A10 decreases expression EXP carvedilol results in decreased expression of S100A10 protein CTD PMID:20403466 NCBI chr 2:181,904,454...181,913,101
Ensembl chr 2:181,904,261...181,913,103 		JBrowse link
G S100a11 S100 calcium binding protein A11 decreases expression EXP carvedilol results in decreased expression of S100A11 protein CTD PMID:20403466 NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541 		JBrowse link
G S100a6 S100 calcium binding protein A6 decreases expression EXP carvedilol results in decreased expression of S100A6 protein CTD PMID:20403466 NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:178,398,481...178,399,762 		JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions EXP carvedilol inhibits the reaction [Norepinephrine results in increased expression of SERPINH1 mRNA]; carvedilol inhibits the reaction [Norepinephrine results in increased expression of SERPINH1 protein] CTD PMID:10722803 NCBI chr 1:163,055,630...163,063,177
Ensembl chr 1:163,055,630...163,062,976 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression
multiple interactions 		ISO Carvedilol results in decreased expression of SLC10A1 protein
[Carvedilol co-treated with Albuterol] results in decreased expression of SLC10A1 protein; Carvedilol inhibits the reaction [Albuterol results in increased expression of SLC10A1 mRNA]; Carvedilol inhibits the reaction [Albuterol results in increased expression of SLC10A1 protein] 		CTD PMID:37632784 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO carvedilol inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Carvedilol inhibits the reaction [SLC22A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; Carvedilol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]; Carvedilol inhibits the reaction [SLC22A2 protein results in increased uptake of Metformin] CTD PMID:19740083 PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO carvedilol inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]; carvedilol inhibits the reaction [SLC22A3 protein results in increased uptake of Metformin] CTD PMID:21641380 PMID:21697722 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO carvedilol inhibits the reaction [SLC22A4 protein results in increased uptake of Tetraethylammonium] CTD PMID:21641380 NCBI chr10:38,634,098...38,687,409
Ensembl chr10:38,634,098...38,679,920 		JBrowse link
G Smad7 SMAD family member 7 multiple interactions EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein] CTD PMID:30254303 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Carvedilol inhibits the reaction [Isoproterenol results in decreased expression of and results in decreased activity of SOD1 protein] CTD PMID:25496245 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP carvedilol inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein] CTD PMID:26036690 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sox2 SRY-box transcription factor 2 increases expression EXP
ISO 		carvedilol results in increased expression of SOX2 mRNA CTD PMID:27288437 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:119,454,541...119,496,350 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP carvedilol inhibits the reaction [Ethanol results in increased expression of SREBF1 mRNA] CTD PMID:22413959 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions EXP Carvedilol inhibits the reaction [Arginine results in increased expression of STAT1 protein] CTD PMID:32569593 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Terf2 telomeric repeat binding factor 2 affects expression EXP carvedilol affects the expression of TERF2 protein CTD PMID:22000973 NCBI chr19:51,887,221...51,915,756
Ensembl chr19:51,887,221...51,915,566 		JBrowse link
G Tfpi tissue factor pathway inhibitor multiple interactions EXP [irbesartan co-treated with carvedilol] results in decreased expression of TFPI mRNA; [irbesartan co-treated with carvedilol] results in decreased expression of TFPI protein CTD PMID:21229253 NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
decreases expression
multiple interactions 		ISO
EXP 		carvedilol results in decreased expression of TGFB1 mRNA
carvedilol decreases expression of TGFbeta mRNA in kidney of high fat high sodium diet fed SHRSP/A3N rats
carvedilol results in decreased expression of TGFB1 mRNA; carvedilol results in decreased expression of TGFB1 protein
Carvedilol inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TGFB1 mRNA]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TGFB1 protein]; Carvedilol inhibits the reaction [Sodium, Dietary results in increased expression of TGFB1 mRNA] 		CTD
RGD		 PMID:11682445 PMID:11688356 PMID:12227681 PMID:15921778 PMID:16310260 More... RGD:30296650 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression 		EXP carvedilol inhibits the reaction [Ethanol results in increased expression of TH protein]
carvedilol results in decreased expression of TH mRNA; carvedilol results in decreased expression of TH protein 		CTD PMID:20359859 PMID:22413959 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions
decreases expression 		EXP carvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA]; carvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 protein]
carvedilol results in decreased expression of TIMP1 mRNA 		CTD PMID:21216836 PMID:22413959 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression 		ISO
EXP 		carvedilol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; carvedilol inhibits the reaction [TNF protein results in increased expression of MMP2 protein]; carvedilol inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
carvedilol results in decreased expression of TNF mRNA; carvedilol results in decreased expression of TNF protein
Carvedilol inhibits the reaction [Arginine results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Aspirin results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; Carvedilol inhibits the reaction [Ethanol results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TNF protein] 		CTD PMID:15229385 PMID:16310260 PMID:17964422 PMID:20017808 PMID:22413959 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 affects expression
multiple interactions 		EXP carvedilol affects the expression of TP53 protein
carvedilol inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein] 		CTD PMID:22000973 PMID:25245570 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Txn1 thioredoxin 1 increases expression EXP carvedilol results in increased expression of TXN1 protein CTD PMID:20403466 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
affects metabolic processing
affects glucuronidation 		ISO UGT1A1 protein results in increased glucuronidation of carvedilol
UGT1A1 gene polymorphism affects the metabolism of carvedilol
UGT1A1 gene polymorphism affects the glucuronidation of carvedilol 		CTD PMID:14744946 PMID:16849011 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation
affects glucuronidation
affects metabolic processing 		ISO UGT2B7 protein results in increased glucuronidation of carvedilol
UGT2B7 gene polymorphism affects the glucuronidation of carvedilol
UGT2B7 gene polymorphism affects the metabolism of carvedilol 		CTD PMID:14744946 PMID:16849011 PMID:17329852 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
G Vim vimentin multiple interactions EXP Carvedilol inhibits the reaction [Carbon Tetrachloride results in increased expression of VIM protein]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of VIM protein] CTD PMID:12140129 PMID:30254303 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
clonidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor multiple interactions EXP [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine CTD PMID:8987795 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2A protein
[5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine 		CTD PMID:10217548 PMID:12560108 PMID:12598592 PMID:16595736 PMID:17934014 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO Clonidine binds to and results in increased activity of ADRA2B protein CTD PMID:10217548 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions
increases response to substance 		ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2C protein
ADRA2C results in increased susceptibility to Clonidine 		CTD PMID:8987795 PMID:10217548 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Clonidine results in increased expression of AIFM1 protein CTD PMID:28115640 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Clonidine results in decreased expression of APOA1 protein CTD PMID:2193493 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Clonidine results in decreased expression of APOA2 protein CTD PMID:2193493 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Avp arginine vasopressin increases expression EXP Clonidine results in increased expression of AVP protein CTD PMID:7400963 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Clonidine results in increased expression of BAD protein CTD PMID:28115640 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Clonidine results in decreased expression of BCL2 protein CTD PMID:28115640 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Clonidine results in increased expression of BCL2L1 mRNA CTD PMID:12423672 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Casp2 caspase 2 increases activity ISO Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity 		EXP
ISO 		Clonidine results in increased expression of CASP3 mRNA
Clonidine results in increased activity of CASP3 protein 		CTD PMID:15351510 PMID:28115640 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases activity ISO Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO Clonidine results in increased activity of CASP9 protein CTD PMID:28115640 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein] CTD PMID:12107048 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Clonidine results in increased expression of COMT mRNA CTD PMID:12423672 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
increases metabolic processing 		ISO [[CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine] which results in decreased chemical synthesis of 4-hydroxyclonidine; [CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine; [CYP2D6 protein results in increased metabolism of Clonidine] which results in increased chemical synthesis of 4-hydroxyclonidine CTD PMID:31585114 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Clonidine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein] CTD PMID:12560108 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gal galanin and GMAP prepropeptide increases activity EXP Clonidine results in increased activity of GAL protein CTD PMID:10818254 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gh1 growth hormone 1 increases secretion
multiple interactions
increases expression 		ISO
EXP 		Clonidine results in increased secretion of GH1 protein
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
L 657743 inhibits the reaction [Clonidine results in increased expression of GH1 protein]
Clonidine results in increased expression of GH1; Clonidine results in increased expression of GH1 protein 		CTD PMID:707001 PMID:2568210 PMID:3007707 PMID:6150000 PMID:15099682 More... NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Gnai1 G protein subunit alpha i1 affects response to substance ISO GNAI1 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G Gnai3 G protein subunit alpha i3 affects response to substance ISO GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Clonidine results in increased expression of HSP90AA1 mRNA CTD PMID:10684495 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Clonidine results in increased expression of HSPD1 mRNA CTD PMID:10684495 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Ifng interferon gamma multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein] CTD PMID:16192389 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 increases secretion ISO Clonidine results in increased secretion of IL10 protein CTD PMID:16612254 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP 		Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein] 		CTD PMID:12065299 PMID:16192389 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein] CTD PMID:16192389 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Ins2 insulin 2 decreases secretion ISO Clonidine results in decreased secretion of INS protein CTD PMID:707001 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Clonidine cotreated with Forearm Reperfusion Injury] increases expression of ITGAM protein in local neutrophils RGD PMID:22987052 RGD:329853767 NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:192,089,542...192,139,943 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of NFKB1 protein] CTD PMID:12065299 PMID:12107048 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nppa natriuretic peptide A increases expression EXP Clonidine results in increased expression of NPPA protein CTD PMID:18378355 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Npy neuropeptide Y increases expression
multiple interactions
decreases expression 		EXP Clonidine results in increased expression of NPY mRNA
Yohimbine inhibits the reaction [Clonidine results in decreased expression of NPY mRNA] 		CTD PMID:1878751 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions
increases response to substance 		EXP [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine
OPRM1 results in increased susceptibility to Clonidine 		CTD PMID:8987795 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Clonidine results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pomc proopiomelanocortin increases expression
multiple interactions
increases secretion
decreases expression 		ISO
EXP 		Clonidine results in increased expression of POMC protein
[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form]
Clonidine results in decreased expression of POMC protein
[Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone 		CTD PMID:2455169 PMID:2846107 PMID:3039113 PMID:6089027 PMID:10898105 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Prl prolactin increases expression
multiple interactions 		ISO
EXP 		Clonidine results in increased expression of PRL protein
Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] 		CTD PMID:1678730 PMID:16401171 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of RELA protein] CTD PMID:12065299 PMID:12107048 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin increases activity
decreases activity
decreases expression
multiple interactions 		ISO Clonidine results in increased activity of REN protein
Clonidine results in decreased activity of REN protein
Clonidine results in decreased expression of REN protein
[Clonidine co-treated with Spironolactone] results in decreased expression of REN protein 		CTD PMID:238481 PMID:998518 PMID:3007707 PMID:3913757 PMID:6337028 More... NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO
EXP 		Clonidine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] 		CTD PMID:9830022 PMID:10966924 PMID:16263091 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions 		ISO Clonidine results in increased activity of TAAR1 protein
[Clonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP 		CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine; [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Norepinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Norepinephrine; Clonidine results in decreased activity of and results in decreased expression of TH protein; Clonidine results in increased activity of and results in increased expression of TH protein CTD PMID:19067675 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein] CTD PMID:16192389 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Clonidine results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tpd52 tumor protein D52 increases expression ISO Clonidine results in increased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
clonidine (amino form) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor multiple interactions EXP [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine CTD PMID:8987795 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2A protein
[5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine 		CTD PMID:10217548 PMID:12560108 PMID:12598592 PMID:16595736 PMID:17934014 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO Clonidine binds to and results in increased activity of ADRA2B protein CTD PMID:10217548 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions
increases response to substance 		ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2C protein
ADRA2C results in increased susceptibility to Clonidine 		CTD PMID:8987795 PMID:10217548 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Clonidine results in increased expression of AIFM1 protein CTD PMID:28115640 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Clonidine results in decreased expression of APOA1 protein CTD PMID:2193493 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Clonidine results in decreased expression of APOA2 protein CTD PMID:2193493 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Avp arginine vasopressin increases expression EXP Clonidine results in increased expression of AVP protein CTD PMID:7400963 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Clonidine results in increased expression of BAD protein CTD PMID:28115640 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Clonidine results in decreased expression of BCL2 protein CTD PMID:28115640 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Clonidine results in increased expression of BCL2L1 mRNA CTD PMID:12423672 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Casp2 caspase 2 increases activity ISO Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity 		EXP
ISO 		Clonidine results in increased expression of CASP3 mRNA
Clonidine results in increased activity of CASP3 protein 		CTD PMID:15351510 PMID:28115640 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases activity ISO Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO Clonidine results in increased activity of CASP9 protein CTD PMID:28115640 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein] CTD PMID:12107048 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Clonidine results in increased expression of COMT mRNA CTD PMID:12423672 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
multiple interactions 		ISO CYP2D6 protein results in increased metabolism of Clonidine
[[CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine] which results in decreased chemical synthesis of 4-hydroxyclonidine; [CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine; [CYP2D6 protein results in increased metabolism of Clonidine] which results in increased chemical synthesis of 4-hydroxyclonidine 		CTD PMID:31585114 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Clonidine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein] CTD PMID:12560108 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gal galanin and GMAP prepropeptide increases activity EXP Clonidine results in increased activity of GAL protein CTD PMID:10818254 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gh1 growth hormone 1 increases secretion
multiple interactions
increases expression 		ISO
EXP 		Clonidine results in increased secretion of GH1 protein
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
L 657743 inhibits the reaction [Clonidine results in increased expression of GH1 protein]
Clonidine results in increased expression of GH1; Clonidine results in increased expression of GH1 protein 		CTD PMID:707001 PMID:2568210 PMID:3007707 PMID:6150000 PMID:15099682 More... NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Gnai1 G protein subunit alpha i1 affects response to substance ISO GNAI1 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G Gnai3 G protein subunit alpha i3 affects response to substance ISO GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Clonidine results in increased expression of HSP90AA1 mRNA CTD PMID:10684495 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Clonidine results in increased expression of HSPD1 mRNA CTD PMID:10684495 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Ifng interferon gamma multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein] CTD PMID:16192389 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 increases secretion ISO Clonidine results in increased secretion of IL10 protein CTD PMID:16612254 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP 		Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein] 		CTD PMID:12065299 PMID:16192389 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein] CTD PMID:16192389 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Ins2 insulin 2 decreases secretion ISO Clonidine results in decreased secretion of INS protein CTD PMID:707001 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of NFKB1 protein] CTD PMID:12065299 PMID:12107048 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nppa natriuretic peptide A increases expression EXP Clonidine results in increased expression of NPPA protein CTD PMID:18378355 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Npy neuropeptide Y increases expression
multiple interactions
decreases expression 		EXP Clonidine results in increased expression of NPY mRNA
Yohimbine inhibits the reaction [Clonidine results in decreased expression of NPY mRNA] 		CTD PMID:1878751 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions
increases response to substance 		EXP [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine
OPRM1 results in increased susceptibility to Clonidine 		CTD PMID:8987795 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Clonidine results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pomc proopiomelanocortin increases expression
multiple interactions
increases secretion
decreases expression 		ISO
EXP 		Clonidine results in increased expression of POMC protein
[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form]
Clonidine results in decreased expression of POMC protein
[Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone 		CTD PMID:2455169 PMID:2846107 PMID:3039113 PMID:6089027 PMID:10898105 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Prl prolactin increases expression
multiple interactions 		ISO
EXP 		Clonidine results in increased expression of PRL protein
Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] 		CTD PMID:1678730 PMID:16401171 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of RELA protein] CTD PMID:12065299 PMID:12107048 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin increases activity
decreases activity
decreases expression
multiple interactions 		ISO Clonidine results in increased activity of REN protein
Clonidine results in decreased activity of REN protein
Clonidine results in decreased expression of REN protein
[Clonidine co-treated with Spironolactone] results in decreased expression of REN protein 		CTD PMID:238481 PMID:998518 PMID:3007707 PMID:3913757 PMID:6337028 More... NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO
EXP 		Clonidine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] 		CTD PMID:9830022 PMID:10966924 PMID:16263091 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions 		ISO Clonidine results in increased activity of TAAR1 protein
[Clonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP 		CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine; [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Norepinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Norepinephrine; Clonidine results in decreased activity of and results in decreased expression of TH protein; Clonidine results in increased activity of and results in increased expression of TH protein CTD PMID:19067675 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein] CTD PMID:16192389 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Clonidine results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tpd52 tumor protein D52 increases expression ISO Clonidine results in increased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
clonidine (imino form) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor multiple interactions EXP [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine CTD PMID:8987795 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2A protein
[5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine results in decreased activity of ADRA2A protein] which results in decreased susceptibility to Clonidine 		CTD PMID:10217548 PMID:12560108 PMID:12598592 PMID:16595736 PMID:17934014 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO Clonidine binds to and results in increased activity of ADRA2B protein CTD PMID:10217548 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions
increases response to substance 		ISO
EXP 		Clonidine binds to and results in increased activity of ADRA2C protein
ADRA2C results in increased susceptibility to Clonidine 		CTD PMID:8987795 PMID:10217548 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Clonidine results in increased expression of AIFM1 protein CTD PMID:28115640 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Apoa1 apolipoprotein A1 decreases expression ISO Clonidine results in decreased expression of APOA1 protein CTD PMID:2193493 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression ISO Clonidine results in decreased expression of APOA2 protein CTD PMID:2193493 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:86,174,741...86,179,410 		JBrowse link
G Avp arginine vasopressin increases expression EXP Clonidine results in increased expression of AVP protein CTD PMID:7400963 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Clonidine results in increased expression of BAD protein CTD PMID:28115640 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Clonidine results in decreased expression of BCL2 protein CTD PMID:28115640 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Clonidine results in increased expression of BCL2L1 mRNA CTD PMID:12423672 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Casp2 caspase 2 increases activity ISO Clonidine results in increased activity of CASP2 protein CTD PMID:28115640 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 increases expression
increases activity 		EXP
ISO 		Clonidine results in increased expression of CASP3 mRNA
Clonidine results in increased activity of CASP3 protein 		CTD PMID:15351510 PMID:28115640 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 increases activity ISO Clonidine results in increased activity of CASP8 protein CTD PMID:28115640 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO Clonidine results in increased activity of CASP9 protein CTD PMID:28115640 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 protein] CTD PMID:12107048 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions ISO Clonidine inhibits the reaction [CFTR protein affects the transport of Chlorides] CTD PMID:12598592 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Clonidine results in increased expression of COMT mRNA CTD PMID:12423672 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing
multiple interactions 		ISO CYP2D6 protein results in increased metabolism of Clonidine
[[CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine] which results in decreased chemical synthesis of 4-hydroxyclonidine; [CYP2D6 gene polymorphism results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Clonidine; [CYP2D6 protein results in increased metabolism of Clonidine] which results in increased chemical synthesis of 4-hydroxyclonidine 		CTD PMID:31585114 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Clonidine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of FOS protein] CTD PMID:12560108 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gal galanin and GMAP prepropeptide increases activity EXP Clonidine results in increased activity of GAL protein CTD PMID:10818254 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Gh1 growth hormone 1 increases secretion
multiple interactions
increases expression 		ISO
EXP 		Clonidine results in increased secretion of GH1 protein
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
L 657743 inhibits the reaction [Clonidine results in increased expression of GH1 protein]
Clonidine results in increased expression of GH1; Clonidine results in increased expression of GH1 protein 		CTD PMID:707001 PMID:2568210 PMID:3007707 PMID:6150000 PMID:15099682 More... NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Gnai1 G protein subunit alpha i1 affects response to substance ISO GNAI1 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198 		JBrowse link
G Gnai3 G protein subunit alpha i3 affects response to substance ISO GNAI3 affects the susceptibility to Clonidine CTD PMID:15207363 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Clonidine results in increased expression of HSP90AA1 mRNA CTD PMID:10684495 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Clonidine results in increased expression of HSPD1 mRNA CTD PMID:10684495 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Ifng interferon gamma multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IFNG protein] CTD PMID:16192389 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il10 interleukin 10 increases secretion ISO Clonidine results in increased secretion of IL10 protein CTD PMID:16612254 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1A protein] CTD PMID:16192389 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP 		Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL1B protein] 		CTD PMID:12065299 PMID:16192389 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of IL2 protein] CTD PMID:16192389 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Ins2 insulin 2 decreases secretion ISO Clonidine results in decreased secretion of INS protein CTD PMID:707001 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of NFKB1 protein] CTD PMID:12065299 PMID:12107048 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nppa natriuretic peptide A increases expression EXP Clonidine results in increased expression of NPPA protein CTD PMID:18378355 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Npy neuropeptide Y increases expression
multiple interactions
decreases expression 		EXP Clonidine results in increased expression of NPY mRNA
Yohimbine inhibits the reaction [Clonidine results in decreased expression of NPY mRNA] 		CTD PMID:1878751 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions
increases response to substance 		EXP [Naloxone binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Clonidine
OPRM1 results in increased susceptibility to Clonidine 		CTD PMID:8987795 NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression ISO Clonidine results in decreased expression of PDCD4 mRNA CTD PMID:21873647 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pomc proopiomelanocortin increases expression
multiple interactions
increases secretion
decreases expression 		ISO
EXP 		Clonidine results in increased expression of POMC protein
[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein; Capsaicin inhibits the reaction [[Clonidine co-treated with Naloxone co-treated with Morphine] results in increased secretion of POMC protein]; Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form]
Clonidine results in decreased expression of POMC protein
[Clonidine results in increased expression of POMC protein] which results in increased susceptibility to Naloxone 		CTD PMID:2455169 PMID:2846107 PMID:3039113 PMID:6089027 PMID:10898105 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Prl prolactin increases expression
multiple interactions 		ISO
EXP 		Clonidine results in increased expression of PRL protein
Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] 		CTD PMID:1678730 PMID:16401171 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Clonidine inhibits the reaction [IL1B protein results in increased activity of [RELA protein binds to NFKB1 protein]]; Clonidine inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of and results in increased activity of RELA protein] CTD PMID:12065299 PMID:12107048 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Ren renin increases activity
decreases activity
decreases expression
multiple interactions 		ISO Clonidine results in increased activity of REN protein
Clonidine results in decreased activity of REN protein
Clonidine results in decreased expression of REN protein
[Clonidine co-treated with Spironolactone] results in decreased expression of REN protein 		CTD PMID:238481 PMID:998518 PMID:3007707 PMID:3913757 PMID:6337028 More... NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC22A1 protein results in increased transport of 1-Methyl-4-phenylpyridinium] CTD PMID:16263091 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC22A2 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:16263091 PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO
EXP 		Clonidine inhibits the reaction [SLC22A3 protein results in increased transport of 1-Methyl-4-phenylpyridinium]; Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium]
Clonidine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] 		CTD PMID:9830022 PMID:10966924 PMID:16263091 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Clonidine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Clonidine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions 		ISO Clonidine results in increased activity of TAAR1 protein
[Clonidine results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP 		CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Dopamine; [Clonidine results in decreased activity of and results in decreased expression of TH protein] which results in decreased abundance of Norepinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Epinephrine; [Clonidine results in increased expression of TH protein] which results in increased abundance of Norepinephrine; Clonidine results in decreased activity of and results in decreased expression of TH protein; Clonidine results in increased activity of and results in increased expression of TH protein CTD PMID:19067675 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP BRL 44408 inhibits the reaction [Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein]]; Clonidine inhibits the reaction [Zymosan results in increased expression of TNF protein] CTD PMID:16192389 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Clonidine results in increased expression of TNFAIP3 mRNA CTD PMID:21873647 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
G Tpd52 tumor protein D52 increases expression ISO Clonidine results in increased expression of TPD52 mRNA CTD PMID:21873647 NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241 		JBrowse link
clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
desipramine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Desipramine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO Desipramine inhibits the reaction [Silicon Dioxide results in increased expression of ACTA2 protein] CTD PMID:34969174 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO Desipramine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Desipramine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression EXP Desipramine results in increased expression of ARC mRNA CTD PMID:14580947 NCBI chr 7:108,444,959...108,448,413
Ensembl chr 7:108,444,692...108,451,220 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Desipramine results in increased expression of BCL2 mRNA; Desipramine results in increased expression of BCL2 protein CTD PMID:17510525 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Desipramine results in increased expression of BDNF mRNA CTD PMID:15555640 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression ISO Desipramine results in decreased expression of CAMKK1 mRNA CTD PMID:15555640 NCBI chr10:58,135,872...58,159,023
Ensembl chr10:58,135,915...58,159,010 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression ISO Desipramine results in decreased expression of CAMKK2 mRNA CTD PMID:15555640 NCBI chr12:39,451,828...39,505,719
Ensembl chr12:39,451,834...39,514,964 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity 		ISO
EXP 		1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester promotes the reaction [Desipramine results in increased cleavage of and results in increased activity of CASP3 protein]; Desipramine results in increased cleavage of and results in increased activity of CASP3 protein
Desipramine results in increased activity of CASP3 protein 		CTD PMID:18606486 PMID:18986328 PMID:20549303 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases activity EXP Desipramine results in increased activity of CASP9 protein CTD PMID:20549303 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Desipramine inhibits the reaction [TNF protein results in increased expression of CCL5 protein] CTD PMID:17477857 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO Desipramine inhibits the reaction [Silicon Dioxide results in decreased expression of CDH1 protein] CTD PMID:34969174 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression EXP Desipramine results in increased expression of CREB1 mRNA CTD PMID:8601816 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Cs citrate synthase multiple interactions ISO Desipramine inhibits the reaction [Glucose results in increased activity of CS protein] CTD PMID:32481596 NCBI chr 7:1,348,389...1,374,624
Ensembl chr 7:1,342,942...1,375,938 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Desipramine results in decreased activity of CYP2C19 protein CTD PMID:15135088 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing ISO CYP2D6 protein affects the metabolism of Desipramine CTD PMID:15286053 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Desipramine results in decreased activity of CYP2E1 protein CTD PMID:15135088 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases response to substance
decreases activity 		ISO CYP3A4 protein results in increased susceptibility to Desipramine
Desipramine results in decreased activity of CYP3A4 protein 		CTD PMID:15135088 PMID:21540358 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance ISO DBH protein results in increased susceptibility to Desipramine CTD PMID:15148402 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:30,886,328...30,903,316 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects response to substance
increases expression 		EXP DDIT3 affects the susceptibility to Desipramine
Desipramine results in increased expression of DDIT3 protein 		CTD PMID:20549303 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Egr1 early growth response 1 decreases expression EXP Desipramine results in decreased expression of EGR1 mRNA CTD PMID:7612155 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Desipramine results in decreased expression of FOS mRNA CTD PMID:7612155 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Desipramine inhibits the reaction [Reserpine results in increased expression of GAL mRNA] CTD PMID:1717808 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 affects localization EXP Desipramine affects the localization of GRK2 protein CTD PMID:12527474 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 affects localization EXP Desipramine affects the localization of GRK3 protein CTD PMID:12527474 NCBI chr12:49,285,228...49,395,803
Ensembl chr12:49,285,263...49,395,802 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions
increases expression 		ISO
EXP 		Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A mRNA]; Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A protein]
Desipramine results in increased expression of HTR1A protein 		CTD PMID:1589591 PMID:15885359 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A decreases expression EXP Desipramine results in decreased expression of HTR2A; Desipramine results in decreased expression of HTR2A protein CTD PMID:1664741 PMID:2553044 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Ifna1 interferon, alpha 1 multiple interactions ISO Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A mRNA]; Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of HTR1A protein]; Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 mRNA]; Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 protein] CTD PMID:15885359 NCBI chr 5:108,143,240...108,143,809
Ensembl chr 5:108,143,240...108,143,809 		JBrowse link
G Il1b interleukin 1 beta increases secretion EXP Desipramine results in increased secretion of IL1B protein CTD PMID:16386803 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Desipramine inhibits the reaction [TNF protein results in increased expression of IL6 protein] CTD PMID:24951586 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Desipramine results in decreased activity of KCNH2 protein CTD PMID:20211602 PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases activity ISO Desipramine results in increased activity of MAPK1 protein CTD PMID:18986328 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases activity ISO Desipramine results in increased activity of MAPK14 protein CTD PMID:18986328 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity ISO Desipramine results in increased activity of MAPK3 protein CTD PMID:18986328 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester promotes the reaction [Desipramine results in increased phosphorylation of MAPK8 protein] CTD PMID:18606486 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Nes nestin increases expression EXP Desipramine results in increased expression of NES mRNA CTD PMID:17510525 NCBI chr 2:175,735,715...175,745,631
Ensembl chr 2:175,736,551...175,746,228 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects response to substance ISO NFE2L2 protein affects the susceptibility to Desipramine CTD PMID:21540358 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Desipramine inhibits the reaction [Silicon Dioxide results in increased expression of NLRP3 protein] CTD PMID:34969174 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 mRNA]; Desipramine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 protein] CTD PMID:15885359 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Plcb1 phospholipase C beta 1 decreases expression EXP Desipramine results in decreased expression of PLCB1 mRNA; Desipramine results in decreased expression of PLCB1 protein CTD PMID:12527476 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Desipramine results in increased expression of PPP1R15A protein CTD PMID:20549303 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774 		JBrowse link
G Slc16a2 solute carrier family 16 member 2 multiple interactions ISO Desipramine inhibits the reaction [SLC16A2 protein results in increased uptake of Triiodothyronine] CTD PMID:28119167 NCBI chr  X:72,791,096...72,914,299
Ensembl chr  X:72,781,876...72,914,498 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression ISO Desipramine results in increased expression of SLC17A7 mRNA; Desipramine results in increased expression of SLC17A7 protein CTD PMID:16111724 NCBI chr 1:104,786,172...104,798,049
Ensembl chr 1:104,785,955...104,798,049 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Desipramine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions EXP
ISO 		Desipramine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
Desipramine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog] 		CTD PMID:9830022 PMID:10966924 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO Desipramine inhibits the reaction [SLC22A7 protein results in increased uptake of Rhodamine 123] CTD PMID:38280639 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions
decreases activity
decreases expression 		ISO
EXP 		Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]]
Desipramine results in decreased activity of SLC6A2 protein
Desipramine results in decreased expression of SLC6A2 protein
[Desipramine binds to and results in decreased activity of SLC6A2 protein] which results in decreased susceptibility to 1-Methyl-4-phenylpyridinium; [Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine; Bupivacaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]; Lidocaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine]; tricaine inhibits the reaction [[Desipramine results in decreased activity of SLC6A2 protein] which results in decreased abundance of Norepinephrine] 		CTD PMID:16725121 PMID:17234900 PMID:18561912 PMID:18923402 PMID:19616025 More... NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 decreases activity ISO Desipramine results in decreased activity of SMPD1 protein CTD PMID:15781658 NCBI chr 1:169,304,772...169,308,615
Ensembl chr 1:169,304,708...169,308,614 		JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions ISO Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Dopamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Octopamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [tryptamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Tyramine results in increased activity of TAAR1 protein]] CTD PMID:17234900 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression EXP Desipramine results in decreased expression of TAC1 protein CTD PMID:8955926 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA] CTD PMID:1717808 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
G Tnf tumor necrosis factor decreases activity
multiple interactions 		ISO Desipramine results in decreased activity of TNF protein
Desipramine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; Desipramine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Desipramine inhibits the reaction [TNF protein results in increased expression of IL6 protein] 		CTD PMID:17477857 PMID:24951586 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
dexmedetomidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Dexmedetomidine binds to and results in increased activity of ADRA2A protein; Dexmedetomidine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein] CTD PMID:10742289 PMID:15627480 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of BAX protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of BAX protein] CTD PMID:30597158 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of BCL2 mRNA]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of BCL2 protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of BCL2 mRNA]] CTD PMID:20003127 PMID:34121490 PMID:36075570 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of BCL2L1 protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of BCL2L1 protein] CTD PMID:30597158 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP1 protein]
Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]] 		CTD PMID:30102002 PMID:36858639 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions 		ISO
EXP 		Dexmedetomidine results in increased activity of CASP3 protein
atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased cleavage of CASP3 protein]]; Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in increased expression of CASP3 protein]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased cleavage of CASP3 protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]] 		CTD PMID:18724006 PMID:19352168 PMID:20003127 PMID:30597158 PMID:34121490 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity ISO Dexmedetomidine results in increased activity of CASP7 protein CTD PMID:18724006 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp8 caspase 8 increases activity ISO Dexmedetomidine results in increased activity of CASP8 protein CTD PMID:18724006 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO Dexmedetomidine results in increased activity of CASP9 protein CTD PMID:18724006 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Dexmedetomidine inhibits the reaction [Ethanol results in increased expression of CCL2 mRNA] CTD PMID:31954762 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions EXP Dexmedetomidine inhibits the reaction [Propofol results in increased expression of CDK5R1 protein] CTD PMID:31187143 NCBI chr10:65,981,692...65,985,831
Ensembl chr10:65,978,911...65,989,272 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:15627480 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]]; atipamezole inhibits the reaction [Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]]; Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Dexmedetomidine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:16510159 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions EXP Dexmedetomidine inhibits the reaction [Propofol results in increased phosphorylation of DPYSL2 protein] CTD PMID:31187143 NCBI chr15:45,181,041...45,287,065
Ensembl chr15:45,181,041...45,287,065 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of DUSP1 protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of DUSP1 protein] CTD PMID:30597158 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions EXP Dexmedetomidine inhibits the reaction [Lidocaine results in increased expression of FOXO3 protein] CTD PMID:32228195 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of GPT protein] CTD PMID:30597158 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gsdmd gasdermin D multiple interactions ISO Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]] CTD PMID:36858639 NCBI chr 7:109,423,209...109,427,771
Ensembl chr 7:109,422,910...109,430,722 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation 		EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased phosphorylation of GSK3B protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased phosphorylation of GSK3B protein]; Dexmedetomidine inhibits the reaction [Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein]
Dexmedetomidine results in increased phosphorylation of GSK3B protein 		CTD PMID:30597158 PMID:31187143 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		EXP
ISO 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 protein]]; atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of HMOX1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of and results in decreased activity of HMOX1 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of HMOX1 mRNA]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of HMOX1 protein]; Dexmedetomidine results in increased expression of and results in increased activity of HMOX1 protein
Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]]
Dexmedetomidine results in increased expression of HMOX1 mRNA 		CTD PMID:30597158 PMID:36027947 PMID:36858639 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hspa12b heat shock protein family A (Hsp70) member 12B multiple interactions ISO Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in decreased expression of HSPA12B mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in decreased expression of HSPA12B protein]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] CTD PMID:38901789 NCBI chr 3:138,799,396...138,817,396
Ensembl chr 3:138,799,398...138,818,935 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions EXP Dexmedetomidine affects the reaction [MIR330 protein affects the expression of HSPD1 mRNA]; Dexmedetomidine inhibits the reaction [Sevoflurane results in decreased expression of HSPD1 mRNA]; Dexmedetomidine inhibits the reaction [Sevoflurane results in decreased expression of HSPD1 protein] CTD PMID:34590382 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]] CTD PMID:36858639 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Dexmedetomidine inhibits the reaction [Ethanol results in increased expression of IL1B mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]
Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL1B protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL1B protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL1B protein]] 		CTD PMID:30102002 PMID:31954762 PMID:36858639 PMID:38901789 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO 		Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Dexmedetomidine promotes the reaction [prolinedithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA]]; prolinedithiocarbamate promotes the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]
Dexmedetomidine inhibits the reaction [Ethanol results in increased expression of IL6 mRNA] 		CTD PMID:29723264 PMID:31954762 PMID:34121490 PMID:36075570 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of LDHA protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of LDHA protein]]; zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of LDHA protein]] CTD PMID:36858639 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions EXP Dexmedetomidine affects the reaction [MIR330 protein affects the lipidation of MAP1LC3B protein]; Dexmedetomidine inhibits the reaction [Sevoflurane results in decreased lipidation of MAP1LC3B protein] CTD PMID:34590382 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of MAPK1 protein] CTD PMID:36027947 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mir134 microRNA 134 multiple interactions EXP Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of MIR134 mRNA]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of BCL2 mRNA]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 mRNA]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF mRNA]] CTD PMID:34121490 NCBI chr 6:134,570,313...134,570,385 JBrowse link
G Mir330 microRNA 330 multiple interactions EXP Dexmedetomidine affects the reaction [MIR330 protein affects the expression of HSPD1 mRNA]; Dexmedetomidine affects the reaction [MIR330 protein affects the lipidation of MAP1LC3B protein]; Dexmedetomidine inhibits the reaction [Sevoflurane results in increased expression of MIR330 mRNA] CTD PMID:34590382 NCBI chr 1:87,961,207...87,961,303
Ensembl chr 1:87,961,207...87,961,303 		JBrowse link
G Mir34a microRNA 34a decreases response to substance EXP MIR34A mRNA results in decreased susceptibility to Dexmedetomidine CTD PMID:35527005 NCBI chr 5:165,815,952...165,816,053
Ensembl chr 5:165,815,952...165,816,053 		JBrowse link
G Mir381 microRNA 381 multiple interactions ISO [Dexmedetomidine co-treated with Lipopolysaccharides] results in increased expression of MIR381 mRNA; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] CTD PMID:30102002 NCBI chr 6:134,562,381...134,562,441 JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein]] CTD PMID:38901789 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
increases phosphorylation 		EXP
ISO 		2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein]]; atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFE2L2 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 mRNA]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of NFE2L2 protein]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased phosphorylation of NFE2L2 protein]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFE2L2 protein]
Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of and results in increased localization of NFE2L2 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of CASP1 protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased cleavage of GSDMD protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL1B protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of LDHA protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein]]; NFE2L2 protein promotes the reaction [Dexmedetomidine promotes the reaction [Ropivacaine results in increased expression of HMOX1 protein]]
Dexmedetomidine results in increased expression of NFE2L2 mRNA; Dexmedetomidine results in increased expression of NFE2L2 protein
Dexmedetomidine results in increased phosphorylation of NFE2L2 protein 		CTD PMID:30597158 PMID:36027947 PMID:36858639 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]
Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein]; NFE2L2 protein promotes the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of NLRP3 protein]] 		CTD PMID:30102002 PMID:36858639 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 protein] CTD PMID:30597158 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions EXP Dexmedetomidine inhibits the reaction [Lidocaine results in increased expression of PRKCB protein] CTD PMID:30240660 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO 		Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of RELA protein]
Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]] 		CTD PMID:29723264 PMID:38901789 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP Dexmedetomidine inhibits the reaction [Lidocaine results in decreased expression of SIRT1 protein] CTD PMID:32228195 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of SOD1 protein]]; Dexmedetomidine inhibits the reaction [Isoflurane results in decreased expression of SOD1 protein] CTD PMID:36027947 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]] CTD PMID:38901789 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO 		Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Dexmedetomidine promotes the reaction [prolinedithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; MIR134 inhibits the reaction [Dexmedetomidine inhibits the reaction [Hydrogen Peroxide results in increased expression of TNF mRNA]]; prolinedithiocarbamate promotes the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
Dexmedetomidine inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; HSPA12B protein affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; MIR381 mRNA affects the reaction [Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] 		CTD PMID:29723264 PMID:30102002 PMID:31954762 PMID:34121490 PMID:36075570 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP atipamezole inhibits the reaction [Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TP53 protein]]; Dexmedetomidine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TP53 protein] CTD PMID:30597158 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions EXP Dexmedetomidine inhibits the reaction [Sevoflurane results in decreased expression of ULK1 mRNA] CTD PMID:34590382 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746 		JBrowse link
doxazosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Doxazosin inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] CTD PMID:11895100 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Adra1a adrenoceptor alpha 1A affects binding EXP
ISO 		Doxazosin binds to ADRA1A protein CTD PMID:7536677 PMID:8183249 PMID:21544540 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B affects binding ISO Doxazosin binds to ADRA1B protein CTD PMID:8183249 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding ISO
EXP 		Doxazosin binds to ADRA1D protein CTD PMID:8183249 PMID:9294627 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions
decreases expression
increases activity 		ISO Doxazosin inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]
Doxazosin results in decreased expression of ADRA2A protein
Doxazosin results in increased activity of ADRA2A protein 		CTD PMID:10694191 PMID:10742289 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adrb1 adrenoceptor beta 1 increases expression EXP Doxazosin results in increased expression of ADRB1 protein CTD PMID:18084315 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Doxazosin results in increased expression of ADRB2 protein CTD PMID:18084315 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects phosphorylation EXP Doxazosin affects the phosphorylation of AKT1 protein CTD PMID:18084315 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		ISO Doxazosin results in increased expression of BAX protein
SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of BAX protein] 		CTD PMID:16007219 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO BCL2 inhibits the reaction [Doxazosin results in decreased expression of VEGFA] CTD PMID:12576871 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions 		ISO Doxazosin results in increased activity of CASP3 protein
Doxazosin results in increased cleavage of and results in increased activity of CASP3 protein 		CTD PMID:12771931 PMID:15221243 PMID:22845314 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Doxazosin results in decreased expression of CCNA2 protein CTD PMID:15371785 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Doxazosin results in increased expression of CDKN1A mRNA CTD PMID:12771931 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Doxazosin inhibits the reaction [Norepinephrine results in increased expression of COL1A1 mRNA] CTD PMID:19575289 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Crp C-reactive protein decreases expression ISO Doxazosin results in decreased expression of CRP protein CTD PMID:16680063 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Doxazosin results in increased expression of DDIT3 protein CTD PMID:22845314 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Epha2 Eph receptor A2 multiple interactions ISO [Doxazosin results in increased phosphorylation of and results in increased activity of EPHA2 protein] which results in increased phosphorylation of and results in increased activity of PTPN11 protein; Doxazosin results in increased phosphorylation of and results in increased activity of EPHA2 protein; Lithocholic Acid inhibits the reaction [Doxazosin results in increased phosphorylation of and results in increased activity of EPHA2 protein] CTD PMID:22845314 NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234 		JBrowse link
G Faslg Fas ligand increases expression ISO Doxazosin results in increased expression of FASLG mRNA CTD PMID:12771931 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Klf10 KLF transcription factor 10 increases expression ISO Doxazosin results in increased expression of KLF10 mRNA; Doxazosin results in increased expression of KLF10 protein CTD PMID:12771931 NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 affects phosphorylation EXP Doxazosin affects the phosphorylation of MAPK1 protein CTD PMID:18084315 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 affects phosphorylation EXP Doxazosin affects the phosphorylation of MAPK3 protein CTD PMID:18084315 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mstn myostatin decreases expression EXP Doxazosin results in decreased expression of MSTN mRNA; Doxazosin results in decreased expression of MSTN protein CTD PMID:16968467 NCBI chr 9:55,944,513...55,950,913
Ensembl chr 9:55,944,513...55,950,913 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO Doxazosin results in increased expression of NFKBIA mRNA; Doxazosin results in increased expression of NFKBIA protein CTD PMID:12771931 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nppb natriuretic peptide B increases expression
multiple interactions 		ISO
EXP 		Doxazosin results in increased expression of NPPB protein
[Atenolol co-treated with Doxazosin] results in decreased expression of NPPB mRNA; [Atenolol co-treated with Losartan co-treated with Doxazosin] results in decreased expression of NPPB mRNA; [Losartan co-treated with Doxazosin] results in decreased expression of NPPB mRNA 		CTD PMID:15969258 PMID:18551024 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression
increases cleavage 		ISO Doxazosin results in decreased expression of PTK2 protein
Doxazosin results in increased cleavage of PTK2 protein 		CTD PMID:15221243 PMID:22845314 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO [Doxazosin results in increased phosphorylation of and results in increased activity of EPHA2 protein] which results in increased phosphorylation of and results in increased activity of PTPN11 protein CTD PMID:22845314 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Rb1 RB transcriptional corepressor 1 affects phosphorylation
decreases phosphorylation 		EXP
ISO 		Doxazosin affects the phosphorylation of RB1 protein
Doxazosin results in decreased phosphorylation of RB1 protein 		CTD PMID:15371785 PMID:18084315 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Ren renin increases expression ISO Doxazosin results in increased expression of REN protein CTD PMID:7818152 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Serpinb5 serpin family B member 5 multiple interactions
increases response to substance 		ISO SERPINB5 protein promotes the reaction [Doxazosin results in decreased expression of VEGFA mRNA alternative form]; SERPINB5 protein promotes the reaction [Doxazosin results in decreased expression of VEGFA protein]; SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of BAX protein]; SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of SMAD4 mRNA]; SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of SMAD4 protein]
SERPINB5 protein results in increased susceptibility to Doxazosin 		CTD PMID:16007219 NCBI chr13:23,500,203...23,520,401
Ensembl chr13:23,500,198...23,520,400 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Doxazosin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Smad4 SMAD family member 4 increases expression
multiple interactions 		ISO Doxazosin results in increased expression of SMAD4 mRNA; Doxazosin results in increased expression of SMAD4 protein
SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of SMAD4 mRNA]; SERPINB5 protein promotes the reaction [Doxazosin results in increased expression of SMAD4 protein] 		CTD PMID:12771931 PMID:16007219 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:69,518,988...69,549,684 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression 		ISO BCL2 inhibits the reaction [Doxazosin results in decreased expression of VEGFA]; SERPINB5 protein promotes the reaction [Doxazosin results in decreased expression of VEGFA mRNA alternative form]; SERPINB5 protein promotes the reaction [Doxazosin results in decreased expression of VEGFA protein]
Doxazosin results in decreased expression of VEGFA mRNA; Doxazosin results in decreased expression of VEGFA mRNA alternative form; Doxazosin results in decreased expression of VEGFA protein 		CTD PMID:12576871 PMID:16007219 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
ergotamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein] CTD PMID:19121572 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Casp3 caspase 3 increases activity ISO Ergotamine results in increased activity of CASP3 protein CTD PMID:21295106 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of FOS protein] CTD PMID:19121572 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Ergotamine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO Ergotamine binds to and results in increased activity of HTR2B protein CTD PMID:11104741 NCBI chr 9:94,184,442...94,206,851
Ensembl chr 9:94,190,109...94,204,087 		JBrowse link
fenoldopam term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3galt2 alpha 1,3-galactosyltransferase 2 increases expression EXP Fenoldopam results in increased expression of A3GALT2 mRNA CTD PMID:21983523 NCBI chr 5:146,385,725...146,398,156
Ensembl chr 5:146,385,746...146,400,043 		JBrowse link
G Abca8a ATP-binding cassette, subfamily A (ABC1), member 8a decreases expression EXP Fenoldopam results in decreased expression of ABCA8A mRNA CTD PMID:21983523 NCBI chr10:95,501,798...95,571,770
Ensembl chr10:95,501,798...95,571,873 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase increases expression EXP Fenoldopam results in increased expression of ABL2 mRNA CTD PMID:21983523 NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775 		JBrowse link
G Actg1 actin, gamma 1 increases expression EXP Fenoldopam results in increased expression of ACTG1 mRNA CTD PMID:21983523 NCBI chr10:106,118,106...106,120,951
Ensembl chr10:106,118,108...106,120,951 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 increases expression EXP Fenoldopam results in increased expression of ADAM9 mRNA CTD PMID:21983523 NCBI chr16:73,725,186...73,804,284
Ensembl chr16:73,725,114...73,804,646 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 decreases expression EXP Fenoldopam results in decreased expression of ADAMTS4 mRNA CTD PMID:21983523 NCBI chr13:86,203,011...86,212,500
Ensembl chr13:86,202,642...86,212,514 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 decreases expression EXP Fenoldopam results in decreased expression of ATP2B2 mRNA CTD PMID:21983523 NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:148,450,207...148,696,239 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression EXP Fenoldopam results in increased expression of B4GALT1 mRNA CTD PMID:21983523 NCBI chr 5:60,731,601...60,778,456
Ensembl chr 5:60,731,602...60,778,445 		JBrowse link
G Calu calumenin increases expression EXP Fenoldopam results in increased expression of CALU mRNA CTD PMID:21983523 NCBI chr 4:58,914,456...58,941,957
Ensembl chr 4:58,914,421...58,941,956 		JBrowse link
G Cbx7 chromobox 7 decreases expression EXP Fenoldopam results in decreased expression of CBX7 mRNA CTD PMID:21983523 NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression EXP Fenoldopam results in increased expression of CD55 mRNA CTD PMID:21983523 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107 		JBrowse link
G Ckap4 cytoskeleton-associated protein 4 increases expression EXP Fenoldopam results in increased expression of CKAP4 mRNA CTD PMID:21983523 NCBI chr 7:21,118,527...21,126,624
Ensembl chr 7:21,118,085...21,126,624 		JBrowse link
G Clic1 chloride intracellular channel 1 increases expression EXP Fenoldopam results in increased expression of CLIC1 mRNA CTD PMID:21983523 NCBI chr20:3,769,522...3,778,367
Ensembl chr20:3,769,527...3,778,367 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain increases expression EXP Fenoldopam results in increased expression of COL12A1 mRNA CTD PMID:21983523 NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711 		JBrowse link
G Drd1 dopamine receptor D1 affects response to substance
multiple interactions 		EXP DRD1 protein affects the susceptibility to Fenoldopam
Fenoldopam binds to and results in increased activity of DRD1 protein 		CTD PMID:1724532 PMID:8103596 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Ecm2 extracellular matrix protein 2 decreases expression EXP Fenoldopam results in decreased expression of ECM2 mRNA CTD PMID:21983523 NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,326,359...15,358,855 		JBrowse link
G Eng endoglin increases expression EXP Fenoldopam results in increased expression of ENG mRNA CTD PMID:21983523 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 increases expression EXP Fenoldopam results in increased expression of ENPP3 mRNA CTD PMID:21983523 NCBI chr 1:22,382,717...22,454,324
Ensembl chr 1:22,382,964...22,454,314 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression EXP Fenoldopam results in increased expression of ERP29 mRNA CTD PMID:21983523 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression EXP Fenoldopam results in increased expression of FGF2 protein CTD PMID:12180796 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fn1 fibronectin 1 increases expression EXP Fenoldopam results in increased expression of FN1 mRNA CTD PMID:21983523 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 decreases expression EXP Fenoldopam results in decreased expression of HMGCS2 mRNA CTD PMID:21983523 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242 		JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 increases expression EXP Fenoldopam results in increased expression of KDELR3 mRNA CTD PMID:21983523 NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 increases expression EXP Fenoldopam results in increased expression of KPNA2 mRNA CTD PMID:21983523 NCBI chr10:92,433,678...92,445,841
Ensembl chr10:92,433,679...92,445,937 		JBrowse link
G Lgmn legumain increases expression EXP Fenoldopam results in increased expression of LGMN mRNA CTD PMID:21983523 NCBI chr 6:127,308,913...127,347,355
Ensembl chr 6:127,308,913...127,347,328 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression EXP Fenoldopam results in increased expression of LITAF mRNA CTD PMID:21983523 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930 		JBrowse link
G Loxl2 lysyl oxidase-like 2 increases expression EXP Fenoldopam results in increased expression of LOXL2 mRNA CTD PMID:21983523 NCBI chr15:51,091,547...51,182,843
Ensembl chr15:51,069,997...51,182,842 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP Fenoldopam results in increased expression of LRAT mRNA CTD PMID:21983523 NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148 		JBrowse link
G Myct1 myc target 1 increases expression EXP Fenoldopam results in increased expression of MYCT1 mRNA CTD PMID:21983523 NCBI chr 1:44,423,478...44,434,751
Ensembl chr 1:44,423,544...44,436,992 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression EXP Fenoldopam results in increased expression of NFKBIZ mRNA CTD PMID:21983523 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP Fenoldopam results in increased expression of NOS2 protein CTD PMID:12180796 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nrip3 nuclear receptor interacting protein 3 increases expression EXP Fenoldopam results in increased expression of NRIP3 mRNA CTD PMID:21983523 NCBI chr 1:173,224,532...173,249,829
Ensembl chr 1:173,224,532...173,251,769 		JBrowse link
G Omd osteomodulin decreases expression EXP Fenoldopam results in decreased expression of OMD mRNA CTD PMID:21983523 NCBI chr17:15,266,646...15,274,870
Ensembl chr17:15,266,646...15,274,870 		JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 increases expression EXP Fenoldopam results in increased expression of PDIA6 mRNA CTD PMID:21983523 NCBI chr 6:45,791,704...45,808,947
Ensembl chr 6:45,791,678...45,810,091 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Fenoldopam results in increased expression of PGK1 mRNA CTD PMID:21983523 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:75,336,687...75,352,959 		JBrowse link
G Plp2 proteolipid protein 2 increases expression EXP Fenoldopam results in increased expression of PLP2 mRNA CTD PMID:21983523 NCBI chr  X:17,506,153...17,509,552
Ensembl chr  X:17,506,059...17,509,550 		JBrowse link
G Pros1 protein S increases expression EXP Fenoldopam results in increased expression of PROS1 mRNA CTD PMID:21983523 NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852 		JBrowse link
G Ptrh1 peptidyl-tRNA hydrolase 1 homolog increases expression EXP Fenoldopam results in increased expression of PTRH1 mRNA CTD PMID:21983523 NCBI chr 3:36,462,575...36,475,605
Ensembl chr 3:36,462,575...36,476,139 		JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP Fenoldopam results in increased expression of RAN mRNA CTD PMID:21983523 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 increases expression EXP Fenoldopam results in increased expression of RANGAP1 mRNA CTD PMID:21983523 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Fenoldopam results in increased expression of S100A11 mRNA CTD PMID:21983523 NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression EXP Fenoldopam results in increased expression of S100A4 mRNA CTD PMID:21983523 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression EXP Fenoldopam results in decreased expression of SLC2A4 mRNA CTD PMID:21983523 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc39a11 solute carrier family 39, member 11 increases expression EXP Fenoldopam results in increased expression of SLC39A11 mRNA CTD PMID:21983523 NCBI chr10:98,775,155...99,196,302
Ensembl chr10:98,776,525...99,107,368 		JBrowse link
G Slc41a2 solute carrier family 41 member 2 increases expression EXP Fenoldopam results in increased expression of SLC41A2 mRNA CTD PMID:21983523 NCBI chr 7:22,271,298...22,378,764
Ensembl chr 7:22,271,313...22,378,764 		JBrowse link
G Sult5a1 sulfotransferase family 5A, member 1 decreases expression EXP Fenoldopam results in decreased expression of SULT5A1 mRNA CTD PMID:21983523 NCBI chr19:68,097,808...68,115,426
Ensembl chr19:68,097,808...68,112,656 		JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions 		ISO Fenoldopam results in increased activity of TAAR1 protein
[Fenoldopam results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP 		CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression EXP Fenoldopam results in increased expression of TGFB1 protein CTD PMID:12180796 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Fenoldopam results in increased expression of THBS1 mRNA CTD PMID:21983523 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Fenoldopam results in increased expression of TIMP1 mRNA CTD PMID:21983523 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tlr2 toll-like receptor 2 increases expression EXP Fenoldopam results in increased expression of TLR2 mRNA CTD PMID:21983523 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194 		JBrowse link
G Tmem97 transmembrane protein 97 increases expression EXP Fenoldopam results in increased expression of TMEM97 mRNA CTD PMID:21983523 NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818 		JBrowse link
G Tnc tenascin C increases expression EXP Fenoldopam results in increased expression of TNC mRNA CTD PMID:21983523 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:82,391,340...82,476,131 		JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression EXP Fenoldopam results in decreased expression of TNFSF10 mRNA CTD PMID:21983523 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP Fenoldopam results in increased expression of TPM4 mRNA CTD PMID:21983523 NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb increases expression EXP Fenoldopam results in increased expression of TUBB4B mRNA CTD PMID:21983523 NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:28,435,148...28,439,719 		JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression EXP Fenoldopam results in increased expression of TUBB5 mRNA CTD PMID:21983523 NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726 		JBrowse link
G Tubb6 tubulin, beta 6 class V increases expression EXP Fenoldopam results in increased expression of TUBB6 mRNA CTD PMID:21983523 NCBI chr18:63,213,287...63,222,926
Ensembl chr18:63,213,279...63,224,303 		JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 increases expression EXP Fenoldopam results in increased expression of UBE2L3 mRNA CTD PMID:21983523 NCBI chr11:97,300,584...97,343,084
Ensembl chr11:97,301,945...97,343,084 		JBrowse link
G Vcan versican increases expression EXP Fenoldopam results in increased expression of VCAN mRNA CTD PMID:21983523 NCBI chr 2:22,497,035...22,595,955
Ensembl chr 2:22,497,035...22,595,955 		JBrowse link
G Vwf von Willebrand factor affects expression EXP Fenoldopam affects the expression of VWF protein CTD PMID:11026604 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
flupenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity 		ISO Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
Flupenthixol analog results in decreased activity of ABCB1 protein; Flupenthixol analog results in decreased activity of ABCB1 protein mutant form 		CTD PMID:7905786 PMID:12711602 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Flupenthixol binds to DRD1 protein CTD PMID:1352677 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Flupenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Flupenthixol results in decreased expression of PTGS1 protein CTD PMID:8897462 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Flupenthixol results in decreased expression of PTGS2 protein CTD PMID:8897462 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
idazoxan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A multiple interactions EXP [Idazoxan binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to amitraz CTD PMID:10582558 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions EXP [Imipramine co-treated with Idazoxan] results in decreased activity of ADRB1 protein CTD PMID:2868116 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Crh corticotropin releasing hormone decreases expression EXP Idazoxan results in decreased expression of CRH mRNA CTD PMID:1351783 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]] CTD PMID:20950675 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Gad2 glutamate decarboxylase 2 multiple interactions EXP [methylhistaprodifen co-treated with Idazoxan] inhibits the reaction [amitraz affects the expression of GAD2 mRNA]; Idazoxan inhibits the reaction [amitraz affects the expression of GAD2 mRNA] CTD PMID:26141220 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:89,671,716...89,941,089 		JBrowse link
G Gh1 growth hormone 1 decreases expression EXP Idazoxan results in decreased expression of GH1 protein CTD PMID:6150737 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859 		JBrowse link
G Gls glutaminase multiple interactions EXP [methylhistaprodifen co-treated with Idazoxan] inhibits the reaction [amitraz results in increased expression of GLS mRNA] CTD PMID:26141220 NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP Idazoxan results in increased expression of NR3C1 mRNA CTD PMID:1351783 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Prl prolactin decreases secretion EXP Idazoxan results in decreased secretion of PRL protein CTD PMID:1678730 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Taar1 trace-amine-associated receptor 1 multiple interactions
increases activity 		ISO [Idazoxan results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP Idazoxan results in increased expression of TH mRNA CTD PMID:1351783 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227 		JBrowse link
ketanserin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions ISO
EXP 		Ketanserin inhibits the reaction [Prazosin binds to ADRA1A protein]
Ketanserin binds to and results in decreased activity of ADRA1A protein 		CTD PMID:11937776 PMID:16545797 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO Ketanserin inhibits the reaction [Prazosin binds to ADRA1B protein] CTD PMID:11937776 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions ISO Ketanserin inhibits the reaction [Prazosin binds to ADRA1D protein] CTD PMID:11937776 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]; Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein] CTD PMID:22975078 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP [Fluoxetine co-treated with Ketanserin] results in increased expression of BDNF mRNA CTD PMID:21627639 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Fluoxetine co-treated with Ketanserin] results in increased expression of CTNNB1 mRNA CTD PMID:21627639 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ddc dopa decarboxylase increases activity ISO Ketanserin results in increased activity of DDC protein CTD PMID:16415089 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
decreases activity
affects binding 		ISO
EXP 		Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein]; Clozapine inhibits the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Ketanserin binds to HTR2A protein]; Quetiapine Fumarate inhibits the reaction [Ketanserin binds to HTR2A protein]; Spiperone inhibits the reaction [Ketanserin binds to HTR2A protein]; ziprasidone inhibits the reaction [Ketanserin binds to HTR2A protein]
Ketanserin results in decreased activity of HTR2A protein
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [Ketanserin binds to HTR2A protein]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in decreased abundance of Serotonin]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in increased secretion of Corticosterone]; [Ketanserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Serotonin; Diazinon promotes the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein; Ketanserin inhibits the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]; Ketanserin inhibits the reaction [Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]]; Ketanserin inhibits the reaction [Tramadol results in increased activity of HTR2A protein]; Risperidone inhibits the reaction [Ketanserin binds to HTR2A protein]
4-iodo-2,5-dimethoxyphenylisopropylamine inhibits the reaction [Ketanserin binds to HTR2A protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Ketanserin binds to HTR2A protein]; HU 211 inhibits the reaction [Ketanserin binds to HTR2A protein]; Ketanserin binds to and results in decreased activity of HTR2A protein 		CTD PMID:2891550 PMID:10773215 PMID:10978843 PMID:11927170 PMID:16314884 More... NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Ketanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP] CTD PMID:14578406 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Ketanserin inhibits the reaction [Serotonin results in increased expression of and results in increased secretion of IL6 protein] CTD PMID:11076827 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO [[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]] CTD PMID:22975078 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ketanserin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK1 protein] CTD PMID:22048642 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ketanserin inhibits the reaction [Tobacco Smoke Pollution results in increased phosphorylation of MAPK3 protein] CTD PMID:22048642 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Ketanserin inhibits the reaction [Tobacco Smoke Pollution affects the localization of NFE2L2 protein] CTD PMID:22048642 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions ISO Ketanserin inhibits the reaction [Serotonin results in increased phosphorylation of PPP1R1B protein] CTD PMID:11880652 NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,844,036...83,853,063 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects binding
multiple interactions 		ISO Ketanserin binds to SLC6A4 protein
methamidophos inhibits the reaction [Ketanserin binds to SLC6A4 protein] 		CTD PMID:21871486 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta multiple interactions ISO [[Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]]] which results in increased ubiquitination of and results in increased degradation of IRS1 protein; [Ketanserin inhibits the reaction [Serotonin results in increased activity of AKT1 protein]] promotes the reaction [Serotonin inhibits the reaction [IRS1 protein binds to YWHAB protein]] CTD PMID:22975078 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854 		JBrowse link
labetalol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Labetalol results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Ace2 angiotensin converting enzyme 2 increases activity ISO Labetalol results in increased activity of ACE2 protein CTD PMID:21859683 NCBI chr  X:33,925,458...33,972,851
Ensembl chr  X:33,925,458...33,971,596 		JBrowse link
G Adrb1 adrenoceptor beta 1 decreases activity
affects binding
increases activity
multiple interactions 		ISO
EXP 		Labetalol results in decreased activity of ADRB1 protein
Labetalol binds to ADRB1 protein
Labetalol results in increased activity of ADRB1 protein
[Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP; CGP 20712A inhibits the reaction [[Labetalol co-treated with ADRB1] results in increased abundance of Cyclic AMP]; CGP 20712A inhibits the reaction [Labetalol results in increased activity of ADRB1 protein]
Labetalol binds to and results in decreased activity of ADRB1 protein; Labetalol inhibits the reaction [CGP 12177 binds to ADRB1 protein]; Labetalol inhibits the reaction [Dihydroalprenolol binds to ADRB1 protein] 		CTD PMID:2462161 PMID:2567112 PMID:11425575 PMID:11483288 PMID:12761341 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237 		JBrowse link
G Adrb2 adrenoceptor beta 2 decreases activity
affects binding
multiple interactions 		ISO
EXP 		Labetalol results in decreased activity of ADRB2 protein
Labetalol binds to ADRB2 protein
[Labetalol binds to ADRB2 protein] which results in increased abundance of Cyclic AMP; [Labetalol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein; [Labetalol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein
Labetalol binds to and results in decreased activity of ADRB2 protein; Labetalol inhibits the reaction [CGP 12177 binds to ADRB2 protein]; Labetalol inhibits the reaction [Dihydroalprenolol binds to ADRB2 protein] 		CTD PMID:2462161 PMID:2567112 PMID:11425575 PMID:11483288 PMID:17925438 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Agt angiotensinogen decreases expression ISO Labetalol results in decreased expression of AGT protein CTD PMID:14627 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Labetalol co-treated with Isoflurane] results in increased expression of AVP protein CTD PMID:1897344 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Labetalol binds to ADRB2 protein] which results in increased phosphorylation of MAPK1 protein CTD PMID:17925438 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Labetalol binds to ADRB2 protein] which results in increased phosphorylation of MAPK3 protein CTD PMID:17925438 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Nppa natriuretic peptide A decreases activity ISO Labetalol results in decreased activity of NPPA protein CTD PMID:2524958 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Prl prolactin multiple interactions
increases expression 		ISO carbidopa, levodopa drug combination inhibits the reaction [Labetalol results in increased expression of PRL protein] CTD PMID:7105431 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Ren renin multiple interactions
decreases activity 		ISO [Labetalol co-treated with Isoflurane] results in increased expression of REN protein
Labetalol results in decreased activity of REN protein 		CTD PMID:1897344 PMID:2524958 PMID:7013770 PMID:7988622 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol; Fluconazole inhibits the reaction [[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol] CTD PMID:18098064 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451 		JBrowse link
methoxamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1d adrenoceptor alpha 1D affects binding ISO Methoxamine binds to ADRA1D protein CTD PMID:15493479 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions
increases secretion 		EXP Pregnanolone inhibits the reaction [Methoxamine results in increased secretion of CRH protein] CTD PMID:7816204 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:104,058,770...104,061,386 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Carbon Tetrachloride co-treated with Phenobarbital co-treated with Methoxamine] results in increased expression of PTGS2 protein CTD PMID:12500202 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Tbxas1 thromboxane A synthase 1 multiple interactions EXP [Carbon Tetrachloride co-treated with Phenobarbital co-treated with Methoxamine] results in increased expression of TBXAS1 protein CTD PMID:12500202 NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969 		JBrowse link
mianserin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor multiple interactions ISO [Caffeine co-treated with Mianserin] results in decreased expression of ADORA1 mRNA CTD PMID:29882086 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Caffeine co-treated with Mianserin] results in decreased expression of COMT mRNA CTD PMID:29882086 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533 		JBrowse link
G Fgf4 fibroblast growth factor 4 decreases expression ISO Mianserin results in decreased expression of FGF4 mRNA CTD PMID:24154490 NCBI chr 1:209,453,229...209,457,085
Ensembl chr 1:209,453,229...209,457,085 		JBrowse link
G Gsc goosecoid homeobox decreases expression ISO Mianserin results in decreased expression of GSC mRNA CTD PMID:24154490 NCBI chr 6:129,152,836...129,154,875
Ensembl chr 6:129,152,836...129,154,875 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [Mianserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; Mianserin binds to and results in decreased activity of HTR2A protein CTD PMID:10764922 PMID:10978843 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C increases expression
multiple interactions 		ISO Mianserin results in increased expression of HTR2C protein
6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [Mianserin results in increased expression of HTR2C protein]; Mianserin binds to and affects the activity of HTR2C protein
[Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine; Mianserin binds to and results in decreased activity of HTR2C protein 		CTD PMID:10978843 PMID:15213358 PMID:18083778 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:115,452,842...115,682,324 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects binding
multiple interactions 		ISO Mianserin binds to HTR7 protein
[Mianserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; Mianserin inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein] 		CTD PMID:14578406 PMID:20827463 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression ISO Mianserin results in decreased expression of ID2 mRNA CTD PMID:24154490 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:38,983,034...39,011,101 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO Mianserin affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:47,531,312...47,778,348
Ensembl chr11:47,531,312...47,778,348 		JBrowse link
G Prkca protein kinase C, alpha decreases expression ISO Mianserin results in decreased expression of PRKCA mRNA CTD PMID:24154490 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Mianserin inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Mianserin inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:21561794 NCBI chr 1:214,951,493...214,960,317
Ensembl chr 1:214,951,867...214,960,311 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 multiple interactions ISO [Caffeine co-treated with Mianserin] results in decreased expression of SLC6A15 mRNA CTD PMID:29882086 NCBI chr 7:40,439,607...40,493,788
Ensembl chr 7:40,439,658...40,493,786 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Mianserin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:19,814,345...19,819,859
Ensembl chr 5:19,814,360...19,819,854 		JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression EXP Mianserin results in decreased expression of TAC1 protein CTD PMID:8955926 NCBI chr 4:36,645,344...36,653,548
Ensembl chr 4:36,645,571...36,653,546 		JBrowse link
midodrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Midodrine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Midodrine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
mirtazapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases export ISO ABCB1 protein results in increased export of mirtazapine CTD PMID:14550684 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:28623179 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions 		EXP Mirtazapine results in decreased phosphorylation of AKT1 protein
Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein] 		CTD PMID:35066094 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Atg7 autophagy related 7 multiple interactions
increases expression 		EXP
ISO 		Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of ATG7 mRNA] CTD PMID:35066094 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Mirtazapine inhibits the reaction [phenylhydrazine results in increased expression of BAX mRNA]; Mirtazapine promotes the reaction [Quercetin inhibits the reaction [phenylhydrazine results in increased expression of BAX mRNA]]; Quercetin promotes the reaction [Mirtazapine inhibits the reaction [phenylhydrazine results in increased expression of BAX mRNA]] CTD PMID:38740240 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of BCL2 mRNA]; Mirtazapine promotes the reaction [Quercetin inhibits the reaction [phenylhydrazine results in decreased expression of BCL2 mRNA]]; Quercetin promotes the reaction [Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of BCL2 mRNA]] CTD PMID:38740240 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression 		ISO
EXP 		Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of BECN1 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of BECN1 protein] 		CTD PMID:35066094 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Mirtazapine inhibits the reaction [phenylhydrazine results in increased expression of CASP3 mRNA]; Mirtazapine promotes the reaction [Quercetin inhibits the reaction [phenylhydrazine results in increased expression of CASP3 mRNA]]; Quercetin promotes the reaction [Mirtazapine inhibits the reaction [phenylhydrazine results in increased expression of CASP3 mRNA]] CTD PMID:38740240 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase multiple interactions EXP mirtazapine inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:19034656 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression 		ISO
EXP 		Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of COL1A1 mRNA] 		CTD PMID:35066094 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460 		JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP mirtazapine results in increased expression of DRD1 mRNA CTD PMID:16499906 NCBI chr17:10,545,488...10,550,029
Ensembl chr17:10,545,111...10,567,166 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP mirtazapine inhibits the reaction [Quinpirole binds to DRD2 protein] CTD PMID:12523492 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions EXP mirtazapine inhibits the reaction [Quinpirole binds to DRD3 protein] CTD PMID:12523492 NCBI chr11:70,385,586...70,437,793
Ensembl chr11:70,385,586...70,446,760 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of FSHB protein]; Mirtazapine promotes the reaction [Quercetin inhibits the reaction [phenylhydrazine results in decreased expression of FSHB protein]]; Quercetin promotes the reaction [Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of FSHB protein]] CTD PMID:38740240 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:114,003,262...114,007,072 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression 		ISO Ethanol promotes the reaction [Mirtazapine results in increased expression of GPT protein] CTD PMID:35066094 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression 		EXP Ethanol promotes the reaction [Mirtazapine results in increased expression of HMGB1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of ATG7 mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of BECN1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased expression of LAMP1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of AKT1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of ATG7 mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of BECN1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of COL1A1 mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of NPPB mRNA]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of TGFB1 mRNA] CTD PMID:35066094 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO mirtazapine results in increased expression of HMGCS1 mRNA CTD PMID:16324787 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
increases expression 		ISO 6-chloro-5-methyl-1-((2-(2-methylpyrid-3-yloxy)pyrid-5-yl)carbamoyl)indoline inhibits the reaction [mirtazapine results in increased expression of HTR2C protein]; mirtazapine binds to and affects the activity of HTR2C protein CTD PMID:18083778 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:115,452,842...115,682,324 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of IL1B protein] CTD PMID:37403423 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of IL6 protein] CTD PMID:37403423 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:38,983,034...39,011,101 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO mirtazapine affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:47,531,312...47,778,348
Ensembl chr11:47,531,312...47,778,348 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions
decreases expression 		EXP Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased expression of LAMP1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased expression of LAMP1 protein] CTD PMID:35066094 NCBI chr16:83,058,131...83,082,843
Ensembl chr16:83,058,385...83,075,159 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of LHB protein]; Quercetin promotes the reaction [Mirtazapine inhibits the reaction [phenylhydrazine results in decreased expression of LHB protein]] CTD PMID:38740240 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:105,037,457...105,038,445 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP mirtazapine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19034656 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions 		EXP Mirtazapine results in decreased phosphorylation of MTOR protein
Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein]]; HMGB1 protein affects the reaction [Mirtazapine results in decreased phosphorylation of MTOR protein] 		CTD PMID:35066094 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression EXP Mirtazapine results in increased expression of NFE2L2 protein CTD PMID:37403423 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of NOX1 protein] CTD PMID:28623179 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:101,572,340...101,595,520 		JBrowse link
G Nppb natriuretic peptide B increases expression
multiple interactions 		ISO
EXP 		Mirtazapine results in increased expression of NPPB mRNA
Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of NPPB mRNA]; Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of NPPB mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of NPPB mRNA] 		CTD PMID:35066094 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression
multiple interactions 		EXP Mirtazapine results in increased expression of PIK3C3 protein
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of PIK3C3 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of PIK3C3 protein] 		CTD PMID:35066094 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539 		JBrowse link
G Prl prolactin increases expression ISO mirtazapine results in increased expression of PRL protein CTD PMID:15105766 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression EXP Mirtazapine results in decreased expression of RELA protein CTD PMID:37403423 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO mirtazapine results in increased expression of SCD mRNA CTD PMID:16324787 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO mirtazapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO mirtazapine results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:55,164,721...55,170,289
Ensembl chr10:55,164,721...55,170,270 		JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression ISO mirtazapine results in increased expression of SLC2A5 mRNA CTD PMID:16002093 NCBI chr 5:165,857,412...165,892,928
Ensembl chr 5:165,866,172...165,894,038 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO mirtazapine inhibits the reaction [Thioacetamide results in increased expression of SMAD3 protein modified form] CTD PMID:28623179 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions 		EXP
ISO 		Mirtazapine results in increased expression of SQSTM1 protein
Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]
3-methyladenine inhibits the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; 3-methyladenine inhibits the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of SQSTM1 protein]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of SQSTM1 protein] 		CTD PMID:35066094 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO mirtazapine results in increased cleavage of and results in increased activity of SREBF1 protein CTD PMID:16324787 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression 		ISO
EXP 		Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]; Mirtazapine inhibits the reaction [Thioacetamide results in increased expression of TGFB1 protein]
Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]; HMGB1 protein affects the reaction [Ethanol promotes the reaction [Mirtazapine results in increased expression of TGFB1 mRNA]]; HMGB1 protein affects the reaction [Mirtazapine results in increased expression of TGFB1 mRNA] 		CTD PMID:28623179 PMID:35066094 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression EXP Mirtazapine results in decreased expression of TLR4 protein CTD PMID:37403423 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Mirtazapine inhibits the reaction [Cadmium results in increased expression of TNF protein] CTD PMID:37403423 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
nefazodone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1cf APOBEC1 complementation factor increases expression EXP nefazodone results in increased expression of A1CF mRNA CTD PMID:24136188 NCBI chr 1:239,149,436...239,242,460
Ensembl chr 1:239,149,493...239,236,817 		JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP nefazodone results in decreased expression of AADAC mRNA CTD PMID:24136188 NCBI chr 2:146,293,449...146,351,061
Ensembl chr 2:146,313,279...146,324,525 		JBrowse link
G Aadat aminoadipate aminotransferase decreases expression EXP nefazodone results in decreased expression of AADAT mRNA CTD PMID:24136188 NCBI chr16:34,520,236...34,566,388
Ensembl chr16:34,520,238...34,566,540 		JBrowse link
G Aamp angio-associated, migratory cell protein increases expression EXP nefazodone results in increased expression of AAMP mRNA CTD PMID:24136188 NCBI chr 9:83,312,519...83,318,325
Ensembl chr 9:83,312,519...83,318,325 		JBrowse link
G Aasdhppt aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase increases expression EXP nefazodone results in increased expression of AASDHPPT mRNA CTD PMID:24136188 NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:9,738,172...9,748,953 		JBrowse link
G Abat 4-aminobutyrate aminotransferase decreases expression EXP nefazodone results in decreased expression of ABAT mRNA CTD PMID:24136188 NCBI chr10:7,503,351...7,599,474
Ensembl chr10:7,492,022...7,599,474 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 decreases expression EXP nefazodone results in decreased expression of ABCA3 mRNA CTD PMID:24136188 NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285 		JBrowse link
G Abca8a ATP-binding cassette, subfamily A (ABC1), member 8a decreases expression EXP nefazodone results in decreased expression of ABCA8A mRNA CTD PMID:24136188 NCBI chr10:95,501,798...95,571,770
Ensembl chr10:95,501,798...95,571,873 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity 		ISO
EXP 		nefazodone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
nefazodone results in decreased expression of ABCB11 mRNA
nefazodone results in decreased activity of ABCB11 protein 		CTD PMID:16410371 PMID:20829430 PMID:22646477 PMID:23956101 PMID:24014644 More... NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
multiple interactions
decreases activity 		EXP
ISO 		nefazodone results in increased expression of ABCB4 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCB4 mRNA
nefazodone results in decreased activity of ABCB4 protein 		CTD PMID:24136188 PMID:28437613 PMID:33819548 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 increases expression EXP nefazodone results in increased expression of ABCB6 mRNA CTD PMID:24136188 NCBI chr 9:84,117,222...84,125,939
Ensembl chr 9:84,117,220...84,125,526 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of ABCC3 mRNA
nefazodone results in decreased expression of ABCC3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ABCC3 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr10:79,793,571...79,839,528
Ensembl chr10:79,793,583...79,839,494 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ABCC4 mRNA
nefazodone results in increased expression of ABCC4 mRNA 		CTD PMID:32152650 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression EXP nefazodone results in decreased expression of ABCC6 mRNA CTD PMID:24136188 NCBI chr 1:105,583,681...105,637,895
Ensembl chr 1:105,583,682...105,637,895 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression EXP nefazodone results in increased expression of ABCE1 mRNA CTD PMID:24136188 NCBI chr19:45,109,880...45,134,819
Ensembl chr19:45,109,906...45,134,819 		JBrowse link
G Abcf3 ATP binding cassette subfamily F member 3 increases expression EXP nefazodone results in increased expression of ABCF3 mRNA CTD PMID:24136188 NCBI chr11:93,844,863...93,856,595
Ensembl chr11:93,844,363...93,856,595 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ABCG2 mRNA CTD PMID:33819548 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Abcg3l2 ATP-binding cassette, subfamily G (WHITE), member 3-like 2 decreases expression EXP nefazodone results in decreased expression of ABCG3L2 mRNA CTD PMID:24136188 NCBI chr14:4,798,053...4,847,424
Ensembl chr14:4,798,053...4,838,117 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of ABCG5 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG5 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:15,717,936...15,743,376 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of ABCG8 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ABCG8 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:15,698,448...15,717,730 		JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression EXP nefazodone results in decreased expression of ABHD1 mRNA CTD PMID:24136188 NCBI chr 6:31,142,476...31,147,464
Ensembl chr 6:31,142,476...31,147,464 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase decreases expression EXP nefazodone results in decreased expression of ABHD2 mRNA CTD PMID:24136188 NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674 		JBrowse link
G Abhd4 abhydrolase domain containing 4, N-acyl phospholipase B increases expression EXP nefazodone results in increased expression of ABHD4 mRNA CTD PMID:24136188 NCBI chr15:31,674,090...31,686,051
Ensembl chr15:31,674,143...31,687,007 		JBrowse link
G Ablim3 actin binding LIM protein family, member 3 increases expression EXP nefazodone results in increased expression of ABLIM3 mRNA CTD PMID:24136188 NCBI chr18:57,527,917...57,646,936
Ensembl chr18:57,527,917...57,646,710 		JBrowse link
G Abtb1 ankyrin repeat and BTB domain containing 1 increases expression EXP nefazodone results in increased expression of ABTB1 mRNA CTD PMID:24136188 NCBI chr 4:122,856,558...122,862,895
Ensembl chr 4:122,856,564...122,862,789 		JBrowse link
G Acaa1a acetyl-CoA acyltransferase 1A increases expression EXP nefazodone results in increased expression of ACAA1 mRNA CTD PMID:24136188 NCBI chr 8:127,956,126...127,966,348
Ensembl chr 8:127,956,129...127,966,241 		JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 increases expression EXP nefazodone results in increased expression of ACAA2 mRNA CTD PMID:24136188 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:70,620,110...70,648,420 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP nefazodone results in decreased expression of ACACA mRNA CTD PMID:24136188 NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,511,857...69,773,888 		JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 increases expression EXP nefazodone results in increased expression of ACAD11 mRNA CTD PMID:24136188 NCBI chr 8:113,560,142...113,625,346
Ensembl chr 8:113,560,196...113,625,352 		JBrowse link
G Acly ATP citrate lyase decreases expression EXP nefazodone results in decreased expression of ACLY mRNA CTD PMID:24136188 NCBI chr10:85,912,402...85,964,605
Ensembl chr10:85,912,402...85,963,631 		JBrowse link
G Aco1 aconitase 1 increases expression EXP nefazodone results in increased expression of ACO1 mRNA CTD PMID:24136188 NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:60,055,866...60,112,600 		JBrowse link
G Aco2 aconitase 2 increases expression EXP nefazodone results in increased expression of ACO2 mRNA CTD PMID:24136188 NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892 		JBrowse link
G Acot12 acyl-CoA thioesterase 12 increases expression EXP nefazodone results in increased expression of ACOT12 mRNA CTD PMID:24136188 NCBI chr 2:24,721,648...24,763,686
Ensembl chr 2:24,721,910...24,765,298 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 decreases expression EXP nefazodone results in decreased expression of ACOT13 mRNA CTD PMID:24136188 NCBI chr17:40,668,404...40,680,876
Ensembl chr17:40,668,316...40,680,876 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP nefazodone results in increased expression of ACOT2 mRNA CTD PMID:24136188 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 increases expression EXP nefazodone results in increased expression of ACOT7 mRNA CTD PMID:24136188 NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033 		JBrowse link
G Acot8 acyl-CoA thioesterase 8 increases expression EXP nefazodone results in increased expression of ACOT8 mRNA CTD PMID:24136188 NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression EXP nefazodone results in increased expression of ACOX1 mRNA CTD PMID:24136188 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136 		JBrowse link
G Acox3 acyl-CoA oxidase 3, pristanoyl decreases expression EXP nefazodone results in decreased expression of ACOX3 mRNA CTD PMID:24136188 NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881 		JBrowse link
G Acp1 acid phosphatase 1 increases expression EXP nefazodone results in increased expression of ACP1 mRNA CTD PMID:24136188 NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959 		JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression EXP nefazodone results in decreased expression of ACP2 mRNA CTD PMID:24136188 NCBI chr 3:97,630,654...97,642,601
Ensembl chr 3:97,631,326...97,642,565 		JBrowse link
G Acsf2 acyl-CoA synthetase family member 2 decreases expression EXP nefazodone results in decreased expression of ACSF2 mRNA CTD PMID:24136188 NCBI chr10:80,001,389...80,043,796
Ensembl chr10:80,001,389...80,045,050 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of ACSL1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ACSL1 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr16:52,487,870...52,554,110
Ensembl chr16:52,487,870...52,554,023 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 increases expression EXP nefazodone results in increased expression of ACSL4 mRNA CTD PMID:24136188 NCBI chr  X:110,739,633...110,803,416
Ensembl chr  X:110,739,648...110,803,261 		JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP nefazodone results in decreased expression of ACSL5 mRNA CTD PMID:24136188 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:264,294,864...264,341,943 		JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP nefazodone results in increased expression of ACSM2A mRNA CTD PMID:24136188 NCBI chr 1:183,347,705...183,386,453
Ensembl chr 1:183,347,705...183,386,453 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP nefazodone results in decreased expression of ACSS2 mRNA CTD PMID:24136188 NCBI chr 3:164,464,124...164,507,607
Ensembl chr 3:164,464,055...164,519,830 		JBrowse link
G Actr3 actin related protein 3 increases expression EXP nefazodone results in increased expression of ACTR3 mRNA CTD PMID:24136188 NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 decreases expression EXP nefazodone results in decreased expression of ADAMTS7 mRNA CTD PMID:24136188 NCBI chr 8:99,584,529...99,624,132
Ensembl chr 8:99,584,529...99,624,132 		JBrowse link
G Adap2 ArfGAP with dual PH domains 2 decreases expression EXP nefazodone results in decreased expression of ADAP2 mRNA CTD PMID:24136188 NCBI chr10:65,635,891...65,665,019
Ensembl chr10:65,622,434...65,664,022 		JBrowse link
G Adck5 aarF domain containing kinase 5 increases expression EXP nefazodone results in increased expression of ADCK5 mRNA CTD PMID:24136188 NCBI chr 7:110,182,275...110,200,088
Ensembl chr 7:110,181,981...110,200,088 		JBrowse link
G Add1 adducin 1 increases expression EXP nefazodone results in increased expression of ADD1 mRNA CTD PMID:24136188 NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of ADGRG1 mRNA CTD PMID:33819548 NCBI chr19:10,009,983...10,047,138
Ensembl chr19:10,010,031...10,047,124 		JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 decreases expression EXP nefazodone results in decreased expression of ADGRL2 mRNA CTD PMID:24136188 NCBI chr 2:240,356,176...240,987,246
Ensembl chr 2:240,356,177...240,855,933 		JBrowse link
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH1C mRNA CTD PMID:33819548 NCBI chr 2:229,470,703...229,482,291
Ensembl chr 2:229,470,703...229,482,291 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of ADH4 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH4 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 2:229,622,092...229,640,120
Ensembl chr 2:229,622,095...229,641,879 		JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ADH6 mRNA CTD PMID:33819548 NCBI chr 2:229,576,612...229,608,359
Ensembl chr 2:229,576,636...229,607,914 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP nefazodone results in decreased expression of ADHFE1 mRNA CTD PMID:24136188 NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835 		JBrowse link
G Adprm ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent increases expression EXP nefazodone results in increased expression of ADPRM mRNA CTD PMID:24136188 NCBI chr10:52,231,085...52,243,637
Ensembl chr10:52,230,233...52,243,569 		JBrowse link
G Adprs ADP-ribosylserine hydrolase increases expression EXP nefazodone results in increased expression of ADPRS mRNA CTD PMID:24136188 NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816 		JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP nefazodone results in decreased expression of ADRA1B mRNA CTD PMID:24136188 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor increases expression EXP nefazodone results in increased expression of ADRM1 mRNA CTD PMID:24136188 NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483 		JBrowse link
G Adsl adenylosuccinate lyase increases expression EXP nefazodone results in increased expression of ADSL mRNA CTD PMID:24136188 NCBI chr 7:114,359,440...114,383,618
Ensembl chr 7:114,359,440...114,384,872 		JBrowse link
G Afg3l2 AFG3 like matrix AAA peptidase subunit 2 increases expression EXP nefazodone results in increased expression of AFG3L2 mRNA CTD PMID:24136188 NCBI chr18:63,224,163...63,269,000
Ensembl chr18:63,224,163...63,269,000 		JBrowse link
G Afm afamin decreases expression EXP nefazodone results in decreased expression of AFM mRNA CTD PMID:24136188 NCBI chr14:17,815,194...17,848,042
Ensembl chr14:17,815,194...17,848,039 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 decreases expression EXP nefazodone results in decreased expression of AGXT2 mRNA CTD PMID:24136188 NCBI chr 2:61,063,416...61,104,828
Ensembl chr 2:61,063,419...61,105,090 		JBrowse link
G Ahcyl1 adenosylhomocysteinase-like 1 increases expression EXP nefazodone results in increased expression of AHCYL1 mRNA CTD PMID:24136188 NCBI chr 2:197,982,335...198,016,770
Ensembl chr 2:197,982,344...198,033,930 		JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 increases expression EXP nefazodone results in increased expression of AHSA1 mRNA CTD PMID:24136188 NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595 		JBrowse link
G Aig1 androgen-induced 1 increases expression EXP nefazodone results in increased expression of AIG1 mRNA CTD PMID:24136188 NCBI chr 1:9,866,546...10,089,454
Ensembl chr 1:9,866,548...10,089,155 		JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression EXP nefazodone results in increased expression of AIMP1 mRNA CTD PMID:24136188 NCBI chr 2:223,825,930...223,849,477
Ensembl chr 2:223,825,931...223,849,994 		JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 increases expression EXP nefazodone results in increased expression of AIMP2 mRNA CTD PMID:24136188 NCBI chr12:15,814,854...15,824,432
Ensembl chr12:15,814,878...15,824,431 		JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein increases expression EXP nefazodone results in increased expression of AIP mRNA CTD PMID:24136188 NCBI chr 1:210,837,473...210,848,691
Ensembl chr 1:210,836,755...210,848,634 		JBrowse link
G Ak3 adenylate kinase 3 increases expression EXP nefazodone results in increased expression of AK3 mRNA CTD PMID:24136188 NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183 		JBrowse link
G Ak4 adenylate kinase 4 decreases expression EXP nefazodone results in decreased expression of AK4 mRNA CTD PMID:24136188 NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401 		JBrowse link
G Akap8l A-kinase anchoring protein 8 like decreases expression EXP nefazodone results in decreased expression of AKAP8L mRNA CTD PMID:24136188 NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression EXP nefazodone results in increased expression of AKR1A1 mRNA CTD PMID:24136188 NCBI chr 5:135,329,605...135,367,037
Ensembl chr 5:135,329,606...135,367,035 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases expression EXP nefazodone results in decreased expression of AKR1C1 mRNA CTD PMID:24136188 NCBI chr17:70,720,397...70,747,285
Ensembl chr17:70,720,398...70,747,247 		JBrowse link
G Akr1c14 aldo-keto reductase family 1, member C14 increases expression EXP nefazodone results in increased expression of AKR1C14 mRNA CTD PMID:24136188 NCBI chr17:71,066,197...71,083,184
Ensembl chr17:71,066,200...71,083,157 		JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of AKR1D1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of AKR1D1 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 4:67,121,288...67,154,543
Ensembl chr 4:67,120,024...67,154,540 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 increases expression EXP nefazodone results in increased expression of AKR7A2 mRNA CTD PMID:24136188 NCBI chr 5:156,835,589...156,844,127
Ensembl chr 5:156,835,551...156,844,109 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression
multiple interactions
decreases expression 		EXP
ISO 		nefazodone results in increased expression of AKR7A3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AKR7A3 mRNA
nefazodone results in decreased expression of AKR7A3 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:156,874,086...156,885,153 		JBrowse link
G Akt1s1 AKT1 substrate 1 increases expression EXP nefazodone results in increased expression of AKT1S1 mRNA CTD PMID:24136188 NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP nefazodone results in increased expression of ALAS1 mRNA CTD PMID:24136188 NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:115,755,238...115,768,642 		JBrowse link
G Alb albumin multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALB mRNA CTD PMID:33819548 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP nefazodone results in increased expression of ALDH1A1 mRNA CTD PMID:24136188 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:227,427,070...227,579,500 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP nefazodone results in increased expression of ALDH1A7 mRNA CTD PMID:24136188 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:227,627,448...227,672,523 		JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression EXP nefazodone results in decreased expression of ALDH1B1 mRNA CTD PMID:24136188 NCBI chr 5:64,859,000...64,864,008
Ensembl chr 5:64,858,934...64,864,365 		JBrowse link
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 increases expression EXP nefazodone results in increased expression of ALDH1L1 mRNA CTD PMID:24136188 NCBI chr 4:124,617,182...124,663,674
Ensembl chr 4:124,617,217...124,664,704 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression EXP nefazodone results in increased expression of ALDH3A2 mRNA CTD PMID:24136188 NCBI chr10:46,427,789...46,448,449
Ensembl chr10:46,407,993...46,448,648 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP nefazodone results in increased expression of ALDOA mRNA CTD PMID:24136188 NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211 		JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression EXP nefazodone results in increased expression of ALG12 mRNA CTD PMID:24136188 NCBI chr 7:121,774,796...121,789,175
Ensembl chr 7:121,768,234...121,788,983 		JBrowse link
G Alg3 ALG3, alpha-1,3- mannosyltransferase increases expression EXP nefazodone results in increased expression of ALG3 mRNA CTD PMID:24136188 NCBI chr11:93,804,859...93,810,403
Ensembl chr11:93,804,891...93,812,060 		JBrowse link
G Alkbh7 alkB homolog 7 increases expression EXP nefazodone results in increased expression of ALKBH7 mRNA CTD PMID:24136188 NCBI chr 9:1,925,896...1,928,048
Ensembl chr 9:1,925,743...1,928,048 		JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of ALPP mRNA CTD PMID:33819548 NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 increases expression EXP nefazodone results in increased expression of AMD1 mRNA CTD PMID:24136188 NCBI chr20:45,250,289...45,324,939
Ensembl chr20:45,250,289...45,265,982 		JBrowse link
G Ammecr1l AMMECR1 like decreases expression EXP nefazodone results in decreased expression of AMMECR1L mRNA CTD PMID:24136188 NCBI chr18:23,661,649...23,685,391
Ensembl chr18:23,661,341...23,685,649 		JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of AMPD3 mRNA CTD PMID:33819548 NCBI chr 1:174,319,526...174,364,605
Ensembl chr 1:174,294,867...174,364,608 		JBrowse link
G Amt aminomethyltransferase increases expression EXP nefazodone results in increased expression of AMT mRNA CTD PMID:24136188 NCBI chr 8:117,859,700...117,866,692
Ensembl chr 8:117,860,345...117,866,803 		JBrowse link
G Amy2a3 amylase 2a3 decreases expression EXP nefazodone results in decreased expression of AMY1A mRNA CTD PMID:24136188 NCBI chr 2:204,005,840...204,014,412
Ensembl chr 2:204,005,840...204,014,413 		JBrowse link
G Ang angiogenin decreases expression EXP nefazodone results in decreased expression of ANG mRNA CTD PMID:24136188 NCBI chr15:26,786,233...26,796,883
Ensembl chr15:26,786,065...26,801,106 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression EXP nefazodone results in decreased expression of ANGPTL3 mRNA CTD PMID:24136188 NCBI chr 5:118,818,494...118,825,531
Ensembl chr 5:118,818,499...118,826,444 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression EXP nefazodone results in decreased expression of ANGPTL4 mRNA CTD PMID:24136188 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP nefazodone results in decreased expression of ANKH mRNA CTD PMID:24136188 NCBI chr 2:79,883,350...80,011,222
Ensembl chr 2:79,883,544...80,011,699 		JBrowse link
G Ankrd13c ankyrin repeat domain 13C decreases expression EXP nefazodone results in decreased expression of ANKRD13C mRNA CTD PMID:24136188 NCBI chr 2:249,679,752...249,729,272
Ensembl chr 2:249,681,872...249,729,272 		JBrowse link
G Anks4b ankyrin repeat and sterile alpha motif domain containing 4B decreases expression EXP nefazodone results in decreased expression of ANKS4B mRNA CTD PMID:24136188 NCBI chr 1:183,934,528...183,989,127
Ensembl chr 1:183,978,769...183,989,122 		JBrowse link
G Ano10 anoctamin 10 increases expression EXP nefazodone results in increased expression of ANO10 mRNA CTD PMID:24136188 NCBI chr 8:130,719,177...130,838,243
Ensembl chr 8:130,718,755...130,877,636 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A decreases expression EXP nefazodone results in decreased expression of ANP32A mRNA CTD PMID:24136188 NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922 		JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B increases expression EXP nefazodone results in increased expression of ANP32B mRNA CTD PMID:24136188 NCBI chr 5:65,538,872...65,561,305
Ensembl chr 5:65,538,535...65,561,437 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP nefazodone results in increased expression of ANP32E mRNA CTD PMID:24136188 NCBI chr 2:186,161,520...186,177,984
Ensembl chr 2:186,161,532...186,177,986 		JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression EXP nefazodone results in decreased expression of ANPEP mRNA CTD PMID:24136188 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101 		JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 decreases expression EXP nefazodone results in decreased expression of ANTXR2 mRNA CTD PMID:24136188 NCBI chr14:11,845,774...11,986,166
Ensembl chr14:11,845,700...11,986,168 		JBrowse link
G Anxa3 annexin A3 decreases expression EXP nefazodone results in decreased expression of ANXA3 mRNA CTD PMID:24136188 NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849 		JBrowse link
G Anxa5 annexin A5 decreases expression EXP nefazodone results in decreased expression of ANXA5 mRNA CTD PMID:24136188 NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400 		JBrowse link
G Anxa7 annexin A7 increases expression EXP nefazodone results in increased expression of ANXA7 mRNA CTD PMID:24136188 NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891 		JBrowse link
G Aox1 aldehyde oxidase 1 increases expression
multiple interactions
decreases expression 		EXP
ISO 		nefazodone results in increased expression of AOX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of AOX1 mRNA
nefazodone results in decreased expression of AOX1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Ap1m1 adaptor related protein complex 1 subunit mu 1 increases expression EXP nefazodone results in increased expression of AP1M1 mRNA CTD PMID:24136188 NCBI chr16:17,620,910...17,636,431
Ensembl chr16:17,616,187...17,636,462 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP nefazodone results in increased expression of AP2M1 mRNA CTD PMID:24136188 NCBI chr11:93,859,690...93,868,600
Ensembl chr11:93,859,690...93,868,480 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases expression EXP nefazodone results in increased expression of APEX1 mRNA CTD PMID:24136188 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329 		JBrowse link
G Api5 apoptosis inhibitor 5 increases expression EXP nefazodone results in increased expression of API5 mRNA CTD PMID:24136188 NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580 		JBrowse link
G Aplp2 amyloid beta precursor like protein 2 decreases expression EXP nefazodone results in decreased expression of APLP2 mRNA CTD PMID:24136188 NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:37,857,407...37,920,031 		JBrowse link
G Apmap adipocyte plasma membrane associated protein decreases expression EXP nefazodone results in decreased expression of APMAP mRNA CTD PMID:24136188 NCBI chr 3:159,869,451...159,897,727
Ensembl chr 3:159,869,451...159,897,726 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of APOA1 mRNA CTD PMID:33819548 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:55,423,825...55,425,729 		JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP nefazodone results in decreased expression of APOA4 mRNA CTD PMID:24136188 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:55,434,168...55,438,164 		JBrowse link
G Apoa5 apolipoprotein A5 decreases expression EXP nefazodone results in decreased expression of APOA5 mRNA CTD PMID:24136188 NCBI chr 8:55,446,329...55,460,509
Ensembl chr 8:55,456,899...55,460,507 		JBrowse link
G Apol2 apolipoprotein L2 decreases expression EXP nefazodone results in decreased expression of APOL3 mRNA CTD PMID:24136188 NCBI chr 7:111,211,944...111,219,209
Ensembl chr 7:111,211,893...111,217,223 		JBrowse link
G Apol9a-Apol7a Apol9a-Apol7a readthrough decreases expression EXP nefazodone results in decreased expression of APOL7B mRNA CTD PMID:24136188 NCBI chr 7:111,011,645...111,019,326
Ensembl chr 7:111,011,645...111,017,084 		JBrowse link
G Apom apolipoprotein M decreases expression EXP nefazodone results in decreased expression of APOM mRNA CTD PMID:24136188 NCBI chr20:3,695,618...3,698,218
Ensembl chr20:3,692,737...3,698,218 		JBrowse link
G Aqp8 aquaporin 8 increases expression EXP nefazodone results in increased expression of AQP8 mRNA CTD PMID:24136188 NCBI chr 1:187,424,314...187,430,243
Ensembl chr 1:187,424,417...187,430,242 		JBrowse link
G Arcn1 archain 1 increases expression EXP nefazodone results in increased expression of ARCN1 mRNA CTD PMID:24136188 NCBI chr 8:53,954,401...53,979,005
Ensembl chr 8:53,954,404...53,979,005 		JBrowse link
G Arf1 ARF GTPase 1 increases expression EXP nefazodone results in increased expression of ARF1 mRNA CTD PMID:24136188 NCBI chr10:44,497,543...44,513,994 JBrowse link
G Arf6 ARF GTPase 6 increases expression EXP nefazodone results in increased expression of ARF6 mRNA CTD PMID:24136188 NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:93,569,234...93,610,536 		JBrowse link
G Arfip2 ARF interacting protein 2 decreases expression EXP nefazodone results in decreased expression of ARFIP2 mRNA CTD PMID:24136188 NCBI chr 1:169,387,484...169,392,290
Ensembl chr 1:169,387,485...169,392,166 		JBrowse link
G Arg1 arginase 1 increases expression EXP nefazodone results in increased expression of ARG1 mRNA CTD PMID:24136188 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713 		JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 decreases expression EXP nefazodone results in decreased expression of ARHGEF19 mRNA CTD PMID:24136188 NCBI chr 5:158,818,840...158,837,196
Ensembl chr 5:158,818,932...158,837,196 		JBrowse link
G Arid1a AT-rich interaction domain 1A decreases expression EXP nefazodone results in decreased expression of ARID1A mRNA CTD PMID:24136188 NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386 		JBrowse link
G Arl4a ARF like GTPase 4A increases expression EXP nefazodone results in increased expression of ARL4A mRNA CTD PMID:24136188 NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760 		JBrowse link
G Arl5a ARF like GTPase 5A increases expression EXP nefazodone results in increased expression of ARL5A mRNA CTD PMID:24136188 NCBI chr 3:57,287,599...57,312,488
Ensembl chr 3:57,289,846...57,312,488 		JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 decreases expression EXP nefazodone results in decreased expression of ARL6IP1 mRNA CTD PMID:24136188 NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232 		JBrowse link
G Arl6ip4 ARF like GTPase 6 interacting protein 4 increases expression EXP nefazodone results in increased expression of ARL6IP4 mRNA CTD PMID:24136188 NCBI chr12:38,140,566...38,142,711
Ensembl chr12:38,140,550...38,142,724 		JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP nefazodone results in increased expression of ARPC5L mRNA CTD PMID:24136188 NCBI chr 3:43,169,518...43,177,224
Ensembl chr 3:43,169,462...43,177,240
Ensembl chr 9:43,169,462...43,177,240 		JBrowse link
G Arpin actin-related protein 2/3 complex inhibitor increases expression EXP nefazodone results in increased expression of ARPIN mRNA CTD PMID:24136188 NCBI chr 1:143,273,590...143,282,426
Ensembl chr 1:143,273,590...143,282,532 		JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression EXP nefazodone results in increased expression of ARPP19 mRNA CTD PMID:24136188 NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385 		JBrowse link
G Arsa arylsulfatase A decreases expression EXP nefazodone results in decreased expression of ARSA mRNA CTD PMID:24136188 NCBI chr 7:122,422,971...122,426,971
Ensembl chr 7:122,422,982...122,428,401 		JBrowse link
G Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 decreases expression EXP nefazodone results in decreased expression of ASAP2 mRNA CTD PMID:24136188 NCBI chr 6:46,386,605...46,549,669
Ensembl chr 6:46,386,605...46,549,669 		JBrowse link
G Asf1a anti-silencing function 1A histone chaperone increases expression EXP nefazodone results in increased expression of ASF1A mRNA CTD PMID:24136188 NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase decreases expression EXP nefazodone results in decreased expression of ASH1L mRNA CTD PMID:24136188 NCBI chr 2:176,644,393...176,780,848
Ensembl chr 2:176,644,924...176,780,847 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP nefazodone results in increased expression of ASNS mRNA CTD PMID:24136188 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Asnsd1 asparagine synthetase domain containing 1 increases expression EXP nefazodone results in increased expression of ASNSD1 mRNA CTD PMID:24136188 NCBI chr 9:55,618,799...55,631,064
Ensembl chr 9:55,618,799...55,631,064 		JBrowse link
G Aspg asparaginase decreases expression EXP nefazodone results in decreased expression of ASPG mRNA CTD PMID:24136188 NCBI chr 6:136,997,832...137,017,417
Ensembl chr 6:136,998,023...137,017,417 		JBrowse link
G Atf1 activating transcription factor 1 increases expression EXP nefazodone results in increased expression of ATF1 mRNA CTD PMID:24136188 NCBI chr 7:133,240,774...133,283,488
Ensembl chr 7:133,241,197...133,283,485 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression 		ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of ATF4 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF4 mRNA
nefazodone results in increased expression of ATF4 mRNA; nefazodone results in increased expression of ATF4 protein 		CTD PMID:27613715 PMID:32152650 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atf5 activating transcription factor 5 increases expression EXP nefazodone results in increased expression of ATF5 mRNA CTD PMID:24136188 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183 		JBrowse link
G Atf6 activating transcription factor 6 increases expression
multiple interactions 		ISO nefazodone results in increased expression of ATF6 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATF6 mRNA 		CTD PMID:32152650 NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033 		JBrowse link
G Atg7 autophagy related 7 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of ATG7 mRNA
nefazodone results in increased expression of ATG7 mRNA 		CTD PMID:32152650 NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:149,391,390...149,598,319 		JBrowse link
G Atg9a autophagy related 9A decreases expression EXP nefazodone results in decreased expression of ATG9A mRNA CTD PMID:24136188 NCBI chr 9:84,126,071...84,136,723
Ensembl chr 9:84,126,071...84,136,666 		JBrowse link
G Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase increases expression EXP nefazodone results in increased expression of ATIC mRNA CTD PMID:24136188 NCBI chr 9:80,614,311...80,634,360
Ensembl chr 9:80,614,283...80,635,756 		JBrowse link
G Atl2 atlastin GTPase 2 increases expression EXP nefazodone results in increased expression of ATL2 mRNA CTD PMID:24136188 NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320 		JBrowse link
G Atl3 atlastin GTPase 3 increases expression EXP nefazodone results in increased expression of ATL3 mRNA CTD PMID:24136188 NCBI chr 1:214,110,127...214,151,098
Ensembl chr 1:214,109,702...214,152,510 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP nefazodone results in decreased expression of ATOH8 mRNA CTD PMID:24136188 NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379 		JBrowse link
G Atosa atos homolog A decreases expression EXP nefazodone results in decreased expression of ATOSA mRNA CTD PMID:24136188 NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091 		JBrowse link
G Atp11a ATPase phospholipid transporting 11A decreases expression EXP nefazodone results in decreased expression of ATP11A mRNA CTD PMID:24136188 NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression EXP nefazodone results in increased expression of ATP5F1D mRNA CTD PMID:24136188 NCBI chr 7:10,211,260...10,218,989
Ensembl chr 7:10,211,262...10,216,583 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP nefazodone results in increased expression of ATP5IF1 mRNA CTD PMID:24136188 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:150,022,960...150,026,677 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 increases expression EXP nefazodone results in increased expression of ATP5MC1 mRNA CTD PMID:24136188 NCBI chr10:81,520,762...81,523,735
Ensembl chr10:81,520,765...81,523,363 		JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d increases expression EXP nefazodone results in increased expression of ATP5PD mRNA CTD PMID:24136188 NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 increases expression EXP nefazodone results in increased expression of ATP6AP2 mRNA CTD PMID:24136188 NCBI chr  X:12,856,708...12,883,670
Ensembl chr  X:12,855,859...12,905,875 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B increases expression EXP nefazodone results in increased expression of ATP6V0B mRNA CTD PMID:24136188 NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression EXP nefazodone results in increased expression of ATP6V0E1 mRNA CTD PMID:24136188 NCBI chr10:16,984,084...17,007,156
Ensembl chr10:16,984,084...17,028,858 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP nefazodone results in increased expression of ATP6V1A mRNA CTD PMID:24136188 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:70,035,134...70,120,603 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 increases expression EXP nefazodone results in increased expression of ATP6V1B2 mRNA CTD PMID:24136188 NCBI chr16:25,384,254...25,408,388
Ensembl chr16:25,384,257...25,408,839 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 increases expression EXP nefazodone results in increased expression of ATP6V1C1 mRNA CTD PMID:24136188 NCBI chr 7:71,719,326...71,757,191
Ensembl chr 7:71,719,404...71,757,184 		JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP nefazodone results in increased expression of ATP6V1D mRNA CTD PMID:24136188 NCBI chr 6:103,389,778...103,405,346
Ensembl chr 6:103,389,783...103,405,346 		JBrowse link
G Atp6v1e1 ATPase H+ transporting V1 subunit E1 increases expression EXP nefazodone results in increased expression of ATP6V1E1 mRNA CTD PMID:24136188 NCBI chr 4:155,694,534...155,716,660
Ensembl chr 4:155,694,534...155,716,678 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F increases expression EXP nefazodone results in increased expression of ATP6V1F mRNA CTD PMID:24136188 NCBI chr 4:59,033,020...59,035,980 JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 increases expression EXP nefazodone results in increased expression of ATP6V1G1 mRNA CTD PMID:24136188 NCBI chr 5:81,976,959...81,983,139
Ensembl chr 5:81,977,015...81,985,930 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H increases expression EXP nefazodone results in increased expression of ATP6V1H mRNA CTD PMID:24136188 NCBI chr 5:19,176,849...19,282,516
Ensembl chr 5:19,176,849...19,282,516 		JBrowse link
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase increases expression EXP nefazodone results in increased expression of ATPSCKMT mRNA CTD PMID:24136188 NCBI chr 2:84,313,991...84,329,195
Ensembl chr 2:84,313,921...84,329,194 		JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO nefazodone results in decreased expression of ATR mRNA CTD PMID:27288927 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718 		JBrowse link
G Atrn attractin decreases expression EXP nefazodone results in decreased expression of ATRN mRNA CTD PMID:24136188 NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase increases expression EXP nefazodone results in increased expression of AUH mRNA CTD PMID:24136188 NCBI chr17:12,481,396...12,576,748
Ensembl chr17:12,481,416...12,602,587 		JBrowse link
G Aup1 AUP1, lipid droplet regulating VLDL assembly factor increases expression EXP nefazodone results in increased expression of AUP1 mRNA CTD PMID:24136188 NCBI chr 4:117,118,035...117,121,063
Ensembl chr 4:117,117,999...117,121,061 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP nefazodone results in decreased expression of AVPR1A mRNA CTD PMID:24136188 NCBI chr 7:59,999,743...60,003,667
Ensembl chr 7:59,999,738...60,003,837 		JBrowse link
G Azi2 5-azacytidine induced 2 increases expression EXP nefazodone results in increased expression of AZI2 mRNA CTD PMID:24136188 NCBI chr 8:126,651,268...126,674,795
Ensembl chr 8:126,651,206...126,676,182 		JBrowse link
G Azin1 antizyme inhibitor 1 increases expression EXP nefazodone results in increased expression of AZIN1 mRNA CTD PMID:24136188 NCBI chr 7:71,539,711...71,566,515
Ensembl chr 7:71,539,711...71,566,515 		JBrowse link
G B2m beta-2 microglobulin decreases expression EXP nefazodone results in decreased expression of B2M mRNA CTD PMID:24136188 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of BAAT mRNA CTD PMID:33819548 NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:68,646,203...68,656,181 		JBrowse link
G Bag3 BAG cochaperone 3 increases expression EXP nefazodone results in increased expression of BAG3 mRNA CTD PMID:24136188 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280 		JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 increases expression EXP nefazodone results in increased expression of BAIAP2L1 mRNA CTD PMID:24136188 NCBI chr12:15,364,090...15,453,602
Ensembl chr12:15,364,109...15,453,605 		JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 increases expression EXP nefazodone results in increased expression of BANF1 mRNA CTD PMID:24136188 NCBI chr 1:212,101,523...212,103,568
Ensembl chr 1:212,101,523...212,103,552 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO nefazodone results in increased expression of BBC3 mRNA CTD PMID:27288927 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 decreases expression EXP nefazodone results in decreased expression of BBOX1 mRNA CTD PMID:24136188 NCBI chr 3:117,277,226...117,326,383
Ensembl chr 3:117,277,226...117,326,064 		JBrowse link
G Bcap29 B-cell receptor-associated protein 29 increases expression EXP nefazodone results in increased expression of BCAP29 mRNA CTD PMID:24136188 NCBI chr 6:53,910,209...53,950,206
Ensembl chr 6:53,910,216...53,949,963 		JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase decreases expression EXP nefazodone results in decreased expression of BCKDK mRNA CTD PMID:24136188 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of BCL2L1 mRNA CTD PMID:33819548 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bcl6 BCL6, transcription repressor increases expression EXP nefazodone results in increased expression of BCL6 mRNA CTD PMID:24136188 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Bcs1l BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone increases expression EXP nefazodone results in increased expression of BCS1L mRNA CTD PMID:24136188 NCBI chr 9:83,614,045...83,618,052
Ensembl chr 9:83,613,975...83,618,257 		JBrowse link
G Bet1 Bet1 golgi vesicular membrane trafficking protein increases expression EXP nefazodone results in increased expression of BET1 mRNA CTD PMID:24136188 NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164 		JBrowse link
G Bgn biglycan decreases expression EXP nefazodone results in decreased expression of BGN mRNA CTD PMID:24136188 NCBI chr  X:156,348,633...156,360,797
Ensembl chr  X:156,348,615...156,360,799 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase decreases expression EXP nefazodone results in decreased expression of BHMT mRNA CTD PMID:24136188 NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:26,594,854...26,614,715 		JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B increases expression EXP nefazodone results in increased expression of BLTP3B mRNA CTD PMID:24136188 NCBI chr 7:26,068,948...26,149,033
Ensembl chr 7:26,068,955...26,149,083 		JBrowse link
G Blvrb biliverdin reductase B increases expression EXP nefazodone results in increased expression of BLVRB mRNA CTD PMID:24136188 NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225 		JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression EXP nefazodone results in decreased expression of BMP1 mRNA CTD PMID:24136188 NCBI chr15:51,961,310...52,005,597
Ensembl chr15:51,961,310...52,005,485 		JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO nefazodone results in increased expression of BMP6 mRNA CTD PMID:32816093 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP nefazodone results in increased expression of BNIP3 mRNA CTD PMID:24136188 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP nefazodone results in increased expression of BNIP3L mRNA CTD PMID:24136188 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Bola3 bolA family member 3 increases expression EXP nefazodone results in increased expression of BOLA3 mRNA CTD PMID:24136188 NCBI chr 4:117,411,044...117,420,491
Ensembl chr 4:117,410,680...117,420,491 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression EXP nefazodone results in increased expression of BOP1 mRNA CTD PMID:24136188 NCBI chr 7:110,052,716...110,076,529
Ensembl chr 7:110,052,720...110,076,529 		JBrowse link
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 increases expression EXP nefazodone results in increased expression of BPNT1 mRNA CTD PMID:24136188 NCBI chr13:99,397,127...99,425,056
Ensembl chr13:99,400,115...99,425,053 		JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 increases expression EXP nefazodone results in increased expression of BPNT2 mRNA CTD PMID:24136188 NCBI chr 5:22,573,241...22,600,126
Ensembl chr 5:22,570,165...22,600,126 		JBrowse link
G Brd10 bromodomain containing 10 decreases expression EXP nefazodone results in decreased expression of BRD10 mRNA CTD PMID:24136188 NCBI chr 1:236,904,520...236,984,414
Ensembl chr 1:236,904,520...236,983,923 		JBrowse link
G Brd3 bromodomain containing 3 decreases expression EXP nefazodone results in decreased expression of BRD3 mRNA CTD PMID:24136188 NCBI chr 3:31,173,332...31,227,749
Ensembl chr 3:31,173,332...31,227,629 		JBrowse link
G Brix1 biogenesis of ribosomes BRX1 increases expression EXP nefazodone results in increased expression of BRIX1 mRNA CTD PMID:24136188 NCBI chr 2:61,177,769...61,188,647
Ensembl chr 2:61,177,771...61,188,647 		JBrowse link
G Brk1 BRICK1 subunit of SCAR/WAVE actin nucleating complex increases expression EXP nefazodone results in increased expression of BRK1 mRNA CTD PMID:24136188 NCBI chr 4:148,306,436...148,321,668
Ensembl chr 4:148,306,398...148,321,984 		JBrowse link
G Btbd1 BTB domain containing 1 decreases expression EXP nefazodone results in decreased expression of BTBD1 mRNA CTD PMID:24136188 NCBI chr 1:145,143,806...145,183,653
Ensembl chr 1:145,143,808...145,181,197 		JBrowse link
G Btf3 basic transcription factor 3 increases expression EXP nefazodone results in increased expression of BTF3 mRNA CTD PMID:24136188 NCBI chr 2:31,394,010...31,401,138
Ensembl chr 2:31,394,011...31,401,125
Ensembl chr13:31,394,011...31,401,125 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 decreases expression EXP nefazodone results in decreased expression of BTG1 mRNA CTD PMID:24136188 NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein increases expression EXP nefazodone results in increased expression of BUB3 mRNA CTD PMID:24136188 NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028 		JBrowse link
G Bysl bystin-like increases expression EXP nefazodone results in increased expression of BYSL mRNA CTD PMID:24136188 NCBI chr 9:20,880,341...20,890,092
Ensembl chr 9:20,880,026...20,890,900 		JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression EXP nefazodone results in increased expression of BZW1 mRNA CTD PMID:24136188 NCBI chr 9:67,424,860...67,438,656
Ensembl chr 9:67,424,866...67,439,684 		JBrowse link
G C10h17orf58 similar to human chromosome 17 open reading frame 58 increases expression EXP nefazodone results in increased expression of C10H17ORF58 mRNA CTD PMID:24136188 NCBI chr10:92,472,779...92,477,330
Ensembl chr10:92,471,934...92,477,330 		JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 increases expression EXP nefazodone results in increased expression of C10H5ORF15 mRNA CTD PMID:24136188 NCBI chr10:37,064,889...37,077,493
Ensembl chr10:37,064,728...37,077,493 		JBrowse link
G C13h1orf115 similar to human chromosome 1 open reading frame 115 decreases expression EXP nefazodone results in decreased expression of C13H1ORF115 mRNA CTD PMID:24136188 NCBI chr13:98,953,841...98,963,577
Ensembl chr13:98,953,843...98,963,810 		JBrowse link
G C18h18orf32 similar to human chromosome 18 open reading frame 32 increases expression EXP nefazodone results in increased expression of C18H18ORF32 mRNA CTD PMID:24136188 NCBI chr18:70,861,434...70,869,983
Ensembl chr18:70,861,435...70,869,983 		JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 increases expression EXP nefazodone results in increased expression of C1GALT1C1 mRNA CTD PMID:24136188 NCBI chr  X:122,243,736...122,248,217
Ensembl chr  X:122,234,454...122,248,422 		JBrowse link
G C1qbp complement C1q binding protein increases expression EXP nefazodone results in increased expression of C1QBP mRNA CTD PMID:24136188 NCBI chr10:56,198,534...56,203,185
Ensembl chr10:56,198,540...56,203,235 		JBrowse link
G C1r complement C1r decreases expression EXP nefazodone results in decreased expression of C1R mRNA CTD PMID:24136188 NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714 		JBrowse link
G C1s complement C1s decreases expression EXP nefazodone results in decreased expression of C1S mRNA CTD PMID:24136188 NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736 		JBrowse link
G C2 complement C2 decreases expression EXP nefazodone results in decreased expression of C2 mRNA CTD PMID:24136188 NCBI chr20:3,944,722...3,975,006
Ensembl chr20:3,955,776...3,981,740 		JBrowse link
G C20h6orf89 similar to human chromosome 6 open reading frame 89 increases expression EXP nefazodone results in increased expression of C20H6ORF89 mRNA CTD PMID:24136188 NCBI chr20:7,324,105...7,368,482
Ensembl chr20:7,324,129...7,363,666 		JBrowse link
G C4b complement C4B decreases expression EXP nefazodone results in decreased expression of C4B mRNA CTD PMID:24136188 NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289 		JBrowse link
G C5 complement C5 decreases expression EXP nefazodone results in decreased expression of C5 mRNA CTD PMID:24136188 NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468 		JBrowse link
G C5h1orf210 similar to human chromosome 1 open reading frame 210 decreases expression EXP nefazodone results in decreased expression of C5H1ORF210 mRNA CTD PMID:24136188 NCBI chr 5:137,334,142...137,337,300
Ensembl chr 5:137,334,142...137,337,300 		JBrowse link
G C6 complement C6 decreases expression EXP nefazodone results in decreased expression of C6 mRNA CTD PMID:24136188 NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120 		JBrowse link
G C8a complement C8 alpha chain decreases expression EXP nefazodone results in decreased expression of C8A mRNA CTD PMID:24136188 NCBI chr 5:124,812,131...124,866,631
Ensembl chr 5:124,812,131...124,866,710 		JBrowse link
G C8b complement C8 beta chain decreases expression EXP nefazodone results in decreased expression of C8B mRNA CTD PMID:24136188 NCBI chr 5:124,763,974...124,801,522
Ensembl chr 5:124,761,790...124,801,516 		JBrowse link
G C8h11orf54 similar to human chromosome 11 open reading frame 54 increases expression EXP nefazodone results in increased expression of C8H11ORF54 mRNA CTD PMID:24136188 NCBI chr 8:20,405,240...20,427,811
Ensembl chr 8:20,405,241...20,427,811 		JBrowse link
G C8h11orf65 similar to human chromosome 11 open reading frame 65 increases expression EXP nefazodone results in increased expression of C8H11ORF65 mRNA CTD PMID:24136188 NCBI chr 8:62,692,123...62,720,951
Ensembl chr 8:62,692,568...62,720,946 		JBrowse link
G C9 complement C9 decreases expression EXP nefazodone results in decreased expression of C9 mRNA CTD PMID:24136188 NCBI chr 2:57,300,510...57,348,759
Ensembl chr 2:57,300,427...57,348,752 		JBrowse link
G C9h2orf69 similar to human chromosome 2 open reading frame 69 increases expression EXP nefazodone results in increased expression of C9H2ORF69 mRNA CTD PMID:24136188 NCBI chr 9:66,444,084...66,452,720
Ensembl chr 9:66,444,112...66,453,983 		JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP nefazodone results in decreased expression of CAR3 mRNA CTD PMID:24136188 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:88,491,670...88,500,524 		JBrowse link
G Ca8 carbonic anhydrase 8 decreases expression EXP nefazodone results in decreased expression of CAR8 mRNA CTD PMID:24136188 NCBI chr 5:26,102,767...26,199,819
Ensembl chr 5:26,102,813...26,199,796 		JBrowse link
G Cab39 calcium binding protein 39 increases expression EXP nefazodone results in increased expression of CAB39 mRNA CTD PMID:24136188 NCBI chr 9:93,911,099...93,972,542
Ensembl chr 9:93,911,054...93,972,542 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C affects activity ISO nefazodone affects the activity of CACNA1C protein CTD PMID:26821276 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:153,436,427...154,051,762 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CACNA2D1 mRNA CTD PMID:33819548 NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147 		JBrowse link
G Cacul1 CDK2-associated, cullin domain 1 increases expression EXP nefazodone results in increased expression of CACUL1 mRNA CTD PMID:24136188 NCBI chr 1:269,652,356...269,712,265
Ensembl chr 1:269,652,356...269,712,112 		JBrowse link
G Cacybp calcyclin binding protein increases expression EXP nefazodone results in increased expression of CACYBP mRNA CTD PMID:24136188 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505 		JBrowse link
G Cald1 caldesmon 1 decreases expression EXP nefazodone results in decreased expression of CALD1 mRNA CTD PMID:24136188 NCBI chr 4:64,232,906...64,414,085
Ensembl chr 4:64,233,171...64,414,085 		JBrowse link
G Calm2 calmodulin 2 decreases expression EXP nefazodone results in decreased expression of CALM2 mRNA CTD PMID:24136188 NCBI chr 6:12,845,170...12,857,830
Ensembl chr15:64,519,554...64,520,657
Ensembl chr 6:64,519,554...64,520,657 		JBrowse link
G Caprin1 cell cycle associated protein 1 increases expression EXP nefazodone results in increased expression of CAPRIN1 mRNA CTD PMID:24136188 NCBI chr 3:110,606,489...110,685,408
Ensembl chr 3:110,606,489...110,685,562 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression EXP nefazodone results in decreased expression of CARHSP1 mRNA CTD PMID:24136188 NCBI chr10:7,453,602...7,467,218
Ensembl chr10:7,452,978...7,467,770 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression 		ISO
EXP 		Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP3 protein]
nefazodone results in increased expression of CASP3 mRNA 		CTD PMID:22700542 PMID:24136188 PMID:27288927 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions 		ISO nefazodone results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [nefazodone results in increased activity of CASP7 protein] 		CTD PMID:22700542 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp9 caspase 9 increases activity ISO nefazodone results in increased activity of CASP9 protein CTD PMID:27288927 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of CAT mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CAT mRNA 		CTD PMID:32152650 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cavin3 caveolae associated protein 3 increases expression EXP nefazodone results in increased expression of CAVIN3 mRNA CTD PMID:24136188 NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981 		JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions
increases expression 		ISO
EXP 		[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CBR1 mRNA
nefazodone results in increased expression of CBR1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr11:46,346,405...46,348,815
Ensembl chr11:46,378,411...46,381,104
Ensembl chr11:46,378,411...46,381,104 		JBrowse link
G Cbr4 carbonyl reductase 4 increases expression EXP nefazodone results in increased expression of CBR4 mRNA CTD PMID:24136188 NCBI chr16:33,625,734...33,695,067
Ensembl chr16:33,617,399...33,656,832 		JBrowse link
G Cbx3 chromobox 3 increases expression EXP nefazodone results in increased expression of CBX3 mRNA CTD PMID:24136188 NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911 		JBrowse link
G Ccdc107 coiled-coil domain containing 107 decreases expression EXP nefazodone results in decreased expression of CCDC107 mRNA CTD PMID:24136188 NCBI chr 5:62,545,273...62,548,711
Ensembl chr 5:62,544,714...62,548,709 		JBrowse link
G Ccdc47 coiled-coil domain containing 47 increases expression EXP nefazodone results in increased expression of CCDC47 mRNA CTD PMID:24136188 NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626 		JBrowse link
G Ccdc6 coiled-coil domain containing 6 increases expression EXP nefazodone results in increased expression of CCDC6 mRNA CTD PMID:24136188 NCBI chr20:18,431,243...18,527,227
Ensembl chr20:18,431,243...18,527,227 		JBrowse link
G Ccdc80 coiled-coil domain containing 80 decreases expression EXP nefazodone results in decreased expression of CCDC80 mRNA CTD PMID:24136188 NCBI chr11:69,191,188...69,224,844
Ensembl chr11:69,191,189...69,224,844 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression EXP nefazodone results in decreased expression of CCL6 mRNA; nefazodone results in decreased expression of CCL9 mRNA CTD PMID:24136188 NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877 		JBrowse link
G Ccnl1 cyclin L1 decreases expression EXP nefazodone results in decreased expression of CCNL1 mRNA CTD PMID:24136188 NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468 		JBrowse link
G Ccnl2 cyclin L2 decreases expression EXP nefazodone results in decreased expression of CCNL2 mRNA CTD PMID:24136188 NCBI chr 5:171,698,951...171,711,037
Ensembl chr 5:171,699,689...171,711,231 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression
multiple interactions 		ISO nefazodone results in increased expression of CCR2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CCR2 mRNA 		CTD PMID:32152650 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059 		JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression EXP nefazodone results in increased expression of CCS mRNA CTD PMID:24136188 NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 increases expression EXP nefazodone results in increased expression of CCT2 mRNA CTD PMID:24136188 NCBI chr 7:54,578,654...54,591,428
Ensembl chr 7:54,578,663...54,592,977 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 increases expression EXP nefazodone results in increased expression of CCT3 mRNA CTD PMID:24136188 NCBI chr 2:176,063,529...176,088,180
Ensembl chr 2:176,063,526...176,089,925 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 increases expression EXP nefazodone results in increased expression of CCT4 mRNA CTD PMID:24136188 NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 increases expression EXP nefazodone results in increased expression of CCT5 mRNA CTD PMID:24136188 NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:84,302,623...84,313,779 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A increases expression EXP nefazodone results in increased expression of CCT6A mRNA CTD PMID:24136188 NCBI chr12:32,508,842...32,519,072
Ensembl chr12:32,508,675...32,519,119 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 increases expression EXP nefazodone results in increased expression of CCT7 mRNA CTD PMID:24136188 NCBI chr 4:119,546,730...119,563,973
Ensembl chr 4:119,546,730...119,563,973 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 increases expression EXP nefazodone results in increased expression of CCT8 mRNA CTD PMID:24136188 NCBI chr11:40,196,619...40,208,328
Ensembl chr11:40,196,619...40,208,328 		JBrowse link
G Cd14 CD14 molecule increases expression EXP nefazodone results in increased expression of CD14 mRNA CTD PMID:24136188 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd164 CD164 molecule decreases expression EXP nefazodone results in decreased expression of CD164 mRNA CTD PMID:24136188 NCBI chr20:46,606,439...46,618,015
Ensembl chr20:46,606,107...46,638,649 		JBrowse link
G Cd302 CD302 molecule decreases expression EXP nefazodone results in decreased expression of CD302 mRNA CTD PMID:24136188 NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:65,113,102...65,164,737 		JBrowse link
G Cd5l Cd5 molecule-like decreases expression EXP nefazodone results in decreased expression of CD5L mRNA CTD PMID:24136188 NCBI chr 2:175,088,915...175,099,928
Ensembl chr 2:175,088,884...175,099,926 		JBrowse link
G Cd74 CD74 molecule decreases expression EXP nefazodone results in decreased expression of CD74 mRNA CTD PMID:24136188 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Cd81 Cd81 molecule decreases expression EXP nefazodone results in decreased expression of CD81 mRNA CTD PMID:24136188 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092 		JBrowse link
G Cd82 Cd82 molecule decreases expression EXP nefazodone results in decreased expression of CD82 mRNA CTD PMID:24136188 NCBI chr 3:99,842,748...99,887,298
Ensembl chr 3:99,842,757...99,886,744 		JBrowse link
G Cdc40 cell division cycle 40 increases expression EXP nefazodone results in increased expression of CDC40 mRNA CTD PMID:24136188 NCBI chr20:45,855,739...45,908,239
Ensembl chr20:45,855,739...45,907,978 		JBrowse link
G Cdc73 cell division cycle 73 increases expression EXP nefazodone results in increased expression of CDC73 mRNA CTD PMID:24136188 NCBI chr13:57,897,924...58,000,031
Ensembl chr13:57,883,983...57,999,978 		JBrowse link
G Cdh2 cadherin 2 decreases expression EXP nefazodone results in decreased expression of CDH2 mRNA CTD PMID:24136188 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP nefazodone results in increased expression of CDK4 mRNA CTD PMID:24136188 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression EXP nefazodone results in increased expression of CDK7 mRNA CTD PMID:24136188 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression EXP nefazodone results in decreased expression of CDO1 mRNA CTD PMID:24136188 NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 decreases expression EXP nefazodone results in decreased expression of CEACAM1 mRNA CTD PMID:24136188 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798 		JBrowse link
G Cela1 chymotrypsin like elastase 1 decreases expression EXP nefazodone results in decreased expression of CELA1 mRNA CTD PMID:24136188 NCBI chr 7:133,651,939...133,665,136
Ensembl chr 7:133,651,941...133,665,061 		JBrowse link
G Cenpv centromere protein V increases expression EXP nefazodone results in increased expression of CENPV mRNA CTD PMID:24136188 NCBI chr10:47,713,778...47,746,800
Ensembl chr10:47,713,778...47,727,679 		JBrowse link
G Cep170 centrosomal protein 170 decreases expression EXP nefazodone results in decreased expression of CEP170 mRNA CTD PMID:24136188 NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990 		JBrowse link
G Ces1e carboxylesterase 1E increases expression EXP nefazodone results in increased expression of CES1E mRNA CTD PMID:24136188 NCBI chr19:30,006,173...30,042,628
Ensembl chr19:30,006,153...30,042,626 		JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP nefazodone results in increased expression of CES2 mRNA CTD PMID:24136188 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752 		JBrowse link
G Cfap20 cilia and flagella associated protein 20 increases expression EXP nefazodone results in increased expression of CFAP20 mRNA CTD PMID:24136188 NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612 		JBrowse link
G Cfap298 cilia and flagella associated protein 298 increases expression EXP nefazodone results in increased expression of CFAP298 mRNA CTD PMID:24136188 NCBI chr11:43,667,996...43,678,049
Ensembl chr11:43,668,014...43,677,382 		JBrowse link
G Cfb complement factor B decreases expression EXP nefazodone results in decreased expression of CFB mRNA CTD PMID:24136188 NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,955,776...3,981,740 		JBrowse link
G Cfh complement factor H decreases expression EXP nefazodone results in decreased expression of CFH mRNA CTD PMID:24136188 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532 		JBrowse link
G Cfhr1 complement factor H-related 1 decreases expression EXP nefazodone results in decreased expression of CFHR1 mRNA CTD PMID:24136188 NCBI chr13:53,946,298...53,961,282
Ensembl chr13:53,919,927...53,961,303 		JBrowse link
G Cgn cingulin decreases expression EXP nefazodone results in decreased expression of CGN mRNA CTD PMID:24136188 NCBI chr 2:184,997,425...185,024,785
Ensembl chr 2:184,997,425...185,023,635 		JBrowse link
G Cgnl1 cingulin-like 1 decreases expression EXP nefazodone results in decreased expression of CGNL1 mRNA CTD PMID:24136188 NCBI chr 8:81,154,169...81,305,598
Ensembl chr 8:81,140,091...81,305,747 		JBrowse link
G Cgrrf1 cell growth regulator with ring finger domain 1 increases expression EXP nefazodone results in increased expression of CGRRF1 mRNA CTD PMID:24136188 NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811 		JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression EXP nefazodone results in decreased expression of CHAC2 mRNA CTD PMID:24136188 NCBI chr14:108,921,669...108,929,215
Ensembl chr14:108,921,341...108,929,469 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 increases expression EXP nefazodone results in increased expression of CHCHD10 mRNA CTD PMID:24136188 NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,277...12,745,677 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 increases expression EXP nefazodone results in increased expression of CHCHD2 mRNA CTD PMID:24136188 NCBI chr12:32,464,847...32,470,871
Ensembl chr12:32,464,824...32,470,871 		JBrowse link
G Chchd5 coiled-coil-helix-coiled-coil-helix domain containing 5 increases expression EXP nefazodone results in increased expression of CHCHD5 mRNA CTD PMID:24136188 NCBI chr 3:136,815,034...136,819,230
Ensembl chr 3:136,815,048...136,821,914 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP nefazodone results in increased expression of CHCHD6 mRNA CTD PMID:24136188 NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421 		JBrowse link
G Chi3l1 chitinase 3 like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CHI3L1 mRNA CTD PMID:33819548 NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825 		JBrowse link
G Chka choline kinase alpha decreases expression EXP nefazodone results in decreased expression of CHKA mRNA CTD PMID:24136188 NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752 		JBrowse link
G Chmp4c charged multivesicular body protein 4C increases expression EXP nefazodone results in increased expression of CHMP4C mRNA CTD PMID:24136188 NCBI chr 2:93,299,152...93,336,075
Ensembl chr 2:93,299,157...93,360,850 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression EXP nefazodone results in increased expression of CHORDC1 mRNA CTD PMID:24136188 NCBI chr 8:23,650,721...23,674,786
Ensembl chr 8:23,650,865...23,677,696 		JBrowse link
G Chpf2 chondroitin polymerizing factor 2 increases expression EXP nefazodone results in increased expression of CHPF2 mRNA CTD PMID:24136188 NCBI chr 4:11,470,917...11,479,096
Ensembl chr 4:11,472,908...11,478,370 		JBrowse link
G Chpt1 choline phosphotransferase 1 increases expression EXP nefazodone results in increased expression of CHPT1 mRNA CTD PMID:24136188 NCBI chr 7:24,753,880...24,802,529
Ensembl chr 7:24,750,343...24,802,521 		JBrowse link
G Chrac1 chromatin accessibility complex subunit 1 increases expression EXP nefazodone results in increased expression of CHRAC1 mRNA CTD PMID:24136188 NCBI chr 7:106,901,841...106,905,441 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex increases expression EXP nefazodone results in increased expression of CHUK mRNA CTD PMID:24136188 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273 		JBrowse link
G Churc1 churchill domain containing 1 increases expression EXP nefazodone results in increased expression of CHURC1 mRNA CTD PMID:24136188 NCBI chr 6:101,203,778...101,218,364
Ensembl chr 6:101,203,841...101,237,748 		JBrowse link
G Ciao2a cytosolic iron-sulfur assembly component 2A increases expression EXP nefazodone results in increased expression of CIAO2A mRNA CTD PMID:24136188 NCBI chr 8:75,565,620...75,577,542
Ensembl chr 8:75,565,567...75,577,541 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 increases expression EXP nefazodone results in increased expression of CIAPIN1 mRNA CTD PMID:24136188 NCBI chr19:10,185,955...10,199,120
Ensembl chr19:10,182,088...10,201,495 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression EXP nefazodone results in increased expression of CIDEA mRNA CTD PMID:24136188 NCBI chr18:63,164,817...63,190,384
Ensembl chr18:63,164,099...63,190,382 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c decreases expression EXP nefazodone results in decreased expression of CIDEC mRNA CTD PMID:24136188 NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP nefazodone results in decreased expression of CITED2 mRNA CTD PMID:24136188 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782 		JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression EXP nefazodone results in increased expression of CKS1B mRNA CTD PMID:24136188 NCBI chr 2:177,130,751...177,135,333
Ensembl chr 2:177,130,777...177,135,365 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP nefazodone results in decreased expression of CKS2 mRNA CTD PMID:24136188 NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519 		JBrowse link
G Clcn3 chloride voltage-gated channel 3 increases expression EXP nefazodone results in increased expression of CLCN3 mRNA CTD PMID:24136188 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984 		JBrowse link
G Clcn4 chloride voltage-gated channel 4 decreases expression EXP nefazodone results in decreased expression of CLCN4 mRNA CTD PMID:24136188 NCBI chr  X:27,290,769...27,356,967
Ensembl chr  X:27,290,868...27,356,939 		JBrowse link
G Cldnd1 claudin domain containing 1 increases expression EXP nefazodone results in increased expression of CLDND1 mRNA CTD PMID:24136188 NCBI chr11:55,352,321...55,358,779
Ensembl chr11:55,352,321...55,358,907 		JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP nefazodone results in decreased expression of CLEC4F mRNA CTD PMID:24136188 NCBI chr 4:117,686,686...117,696,407
Ensembl chr 4:117,686,686...117,696,438 		JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression EXP nefazodone results in increased expression of CLIP1 mRNA CTD PMID:24136188 NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit increases expression EXP nefazodone results in increased expression of CLPP mRNA CTD PMID:24136188 NCBI chr 9:1,917,305...1,924,706
Ensembl chr 9:1,918,682...1,924,705 		JBrowse link
G Cltb clathrin, light chain B increases expression EXP nefazodone results in increased expression of CLTB mRNA CTD PMID:24136188 NCBI chr17:10,006,416...10,024,278
Ensembl chr17:10,006,656...10,024,915 		JBrowse link
G Cltc clathrin heavy chain increases expression EXP nefazodone results in increased expression of CLTC mRNA CTD PMID:24136188 NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691 		JBrowse link
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase increases expression EXP nefazodone results in increased expression of CMAS mRNA CTD PMID:24136188 NCBI chr 4:177,449,801...177,468,117
Ensembl chr 4:177,449,732...177,476,291 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog increases expression EXP nefazodone results in increased expression of CMBL mRNA CTD PMID:24136188 NCBI chr 2:84,280,128...84,301,878
Ensembl chr 2:84,242,512...84,301,880 		JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 decreases expression EXP nefazodone results in decreased expression of CMTM6 mRNA CTD PMID:24136188 NCBI chr 8:123,301,131...123,319,230
Ensembl chr 8:123,300,918...123,319,230 		JBrowse link
G Cmtm8 CKLF-like MARVEL transmembrane domain containing 8 increases expression EXP nefazodone results in increased expression of CMTM8 mRNA CTD PMID:24136188 NCBI chr 8:123,360,168...123,425,291
Ensembl chr 8:123,360,170...123,425,276 		JBrowse link
G Cnot11 CCR4-NOT transcription complex, subunit 11 increases expression EXP nefazodone results in increased expression of CNOT11 mRNA CTD PMID:24136188 NCBI chr 9:49,310,624...49,320,325
Ensembl chr 9:49,309,518...49,321,771 		JBrowse link
G Coa3 cytochrome C oxidase assembly factor 3 increases expression EXP nefazodone results in increased expression of COA3 mRNA CTD PMID:24136188 NCBI chr10:86,720,454...86,721,435
Ensembl chr10:86,720,456...86,721,440 		JBrowse link
G Coa5 cytochrome C oxidase assembly factor 5 increases expression EXP nefazodone results in increased expression of COA5 mRNA CTD PMID:24136188 NCBI chr 9:47,147,267...47,160,724
Ensembl chr 9:47,147,267...47,160,672 		JBrowse link
G Coasy Coenzyme A synthase increases expression EXP nefazodone results in increased expression of COASY mRNA CTD PMID:24136188 NCBI chr10:86,514,850...86,519,130
Ensembl chr10:86,514,874...86,519,130 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 increases expression EXP nefazodone results in increased expression of COG6 mRNA CTD PMID:24136188 NCBI chr 2:139,212,459...139,249,505
Ensembl chr 2:139,211,678...139,249,737 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain decreases expression EXP nefazodone results in decreased expression of COL14A1 mRNA CTD PMID:24136188 NCBI chr 7:88,611,827...88,826,939
Ensembl chr 7:88,611,828...88,826,938 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP nefazodone results in decreased expression of COL18A1 mRNA CTD PMID:24136188 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP nefazodone results in decreased expression of COL1A2 mRNA CTD PMID:24136188 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression EXP nefazodone results in decreased expression of COL3A1 mRNA CTD PMID:24136188 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression EXP nefazodone results in decreased expression of COL6A1 mRNA CTD PMID:24136188 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,457...11,924,107 		JBrowse link
G Commd5 COMM domain containing 5 increases expression EXP nefazodone results in increased expression of COMMD5 mRNA CTD PMID:24136188 NCBI chr 7:110,502,492...110,503,916
Ensembl chr 7:110,479,403...110,505,897 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 increases expression EXP nefazodone results in increased expression of COMTD1 mRNA CTD PMID:24136188 NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232 		JBrowse link
G Cope COPI coat complex subunit epsilon increases expression EXP nefazodone results in increased expression of COPE mRNA CTD PMID:24136188 NCBI chr16:19,148,832...19,159,052
Ensembl chr16:19,148,832...19,159,212 		JBrowse link
G Cops4 COP9 signalosome subunit 4 increases expression EXP nefazodone results in increased expression of COPS4 mRNA CTD PMID:24136188 NCBI chr14:9,382,897...9,413,216
Ensembl chr14:9,382,900...9,413,107 		JBrowse link
G Cops5 COP9 signalosome subunit 5 increases expression EXP nefazodone results in increased expression of COPS5 mRNA CTD PMID:24136188 NCBI chr 5:13,975,198...13,993,391
Ensembl chr 5:13,975,052...13,993,387 		JBrowse link
G Cops7a COP9 signalosome subunit 7A increases expression EXP nefazodone results in increased expression of COPS7A mRNA CTD PMID:24136188 NCBI chr 4:159,452,878...159,478,878
Ensembl chr 4:159,452,897...159,460,315 		JBrowse link
G Coq10a coenzyme Q10A decreases expression EXP nefazodone results in decreased expression of COQ10A mRNA CTD PMID:24136188 NCBI chr 7:1,376,591...1,387,694
Ensembl chr 7:1,376,591...1,382,722 		JBrowse link
G Coq6 coenzyme Q6 monooxygenase increases expression EXP nefazodone results in increased expression of COQ6 mRNA CTD PMID:24136188 NCBI chr 6:109,738,934...109,750,315
Ensembl chr 6:109,738,951...109,750,310 		JBrowse link
G Coq8a coenzyme Q8A decreases expression EXP nefazodone results in decreased expression of COQ8A mRNA CTD PMID:24136188 NCBI chr13:94,436,680...94,465,535
Ensembl chr13:94,436,546...94,463,378 		JBrowse link
G Coro1c coronin 1C decreases expression EXP nefazodone results in decreased expression of CORO1C mRNA CTD PMID:24136188 NCBI chr12:48,373,573...48,445,718
Ensembl chr12:48,373,597...48,445,716 		JBrowse link
G Cox14 cytochrome c oxidase assembly factor COX14 increases expression EXP nefazodone results in increased expression of COX14 mRNA CTD PMID:24136188 NCBI chr 7:132,731,069...132,733,159
Ensembl chr 7:132,731,069...132,733,159 		JBrowse link
G Cox19 cytochrome c oxidase assembly factor COX19 increases expression EXP nefazodone results in increased expression of COX19 mRNA CTD PMID:24136188 NCBI chr12:20,417,389...20,426,868
Ensembl chr12:20,417,341...20,426,868 		JBrowse link
G Cp ceruloplasmin decreases expression EXP nefazodone results in decreased expression of CP mRNA CTD PMID:24136188 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Cpb2 carboxypeptidase B2 decreases expression EXP nefazodone results in decreased expression of CPB2 mRNA CTD PMID:24136188 NCBI chr15:56,967,128...57,015,964
Ensembl chr15:56,966,839...57,015,962 		JBrowse link
G Cpox coproporphyrinogen oxidase increases expression EXP nefazodone results in increased expression of CPOX mRNA CTD PMID:24136188 NCBI chr11:55,405,778...55,415,761
Ensembl chr11:55,405,784...55,415,761 		JBrowse link
G Cpq carboxypeptidase Q decreases expression EXP nefazodone results in decreased expression of PGCP mRNA CTD PMID:24136188 NCBI chr 7:66,148,973...66,719,189
Ensembl chr 7:66,149,377...66,716,137 		JBrowse link
G Cps1 carbamoyl-phosphate synthase 1 decreases expression EXP nefazodone results in decreased expression of CPS1 mRNA CTD PMID:24136188 NCBI chr 9:76,063,863...76,186,739
Ensembl chr 9:76,000,754...76,186,734 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 increases expression EXP nefazodone results in increased expression of CPSF3 mRNA CTD PMID:24136188 NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP nefazodone results in increased expression of CPT1A mRNA CTD PMID:24136188 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression EXP nefazodone results in increased expression of CPT2 mRNA CTD PMID:24136188 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:127,893,207...127,910,818 		JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP nefazodone results in increased expression of CRAT mRNA CTD PMID:24136188 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression EXP nefazodone results in increased expression of CREB3 mRNA CTD PMID:24136188 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:62,613,638...62,619,500 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 increases expression EXP nefazodone results in increased expression of CREB3L3 mRNA CTD PMID:24136188 NCBI chr 7:9,273,320...9,281,755
Ensembl chr 7:9,273,338...9,281,778 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression EXP nefazodone results in increased expression of CREG1 mRNA CTD PMID:24136188 NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272 		JBrowse link
G Creld1 cysteine-rich with EGF-like domains 1 increases expression EXP nefazodone results in increased expression of CRELD1 mRNA CTD PMID:24136188 NCBI chr 4:148,187,510...148,197,120
Ensembl chr 4:148,187,265...148,197,116 		JBrowse link
G Crem cAMP responsive element modulator decreases expression EXP nefazodone results in decreased expression of CREM mRNA CTD PMID:24136188 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crip2 cysteine-rich protein 2 decreases expression EXP nefazodone results in decreased expression of CRIP2 mRNA CTD PMID:24136188 NCBI chr 6:138,042,175...138,047,121
Ensembl chr 6:138,041,906...138,047,120 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression EXP nefazodone results in decreased expression of CROT mRNA CTD PMID:24136188 NCBI chr 4:26,031,729...26,088,057
Ensembl chr 4:26,052,516...26,088,064 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP nefazodone results in decreased expression of CRY1 mRNA CTD PMID:24136188 NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822 		JBrowse link
G Crybg2 crystallin beta-gamma domain containing 2 decreases expression EXP nefazodone results in decreased expression of CRYBG2 mRNA CTD PMID:24136188 NCBI chr 5:151,570,154...151,602,164
Ensembl chr 5:151,570,540...151,602,163 		JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP nefazodone results in increased expression of CRYL1 mRNA CTD PMID:24136188 NCBI chr15:35,542,628...35,661,563
Ensembl chr15:35,542,628...35,661,563 		JBrowse link
G Cse1l chromosome segregation 1 like increases expression EXP nefazodone results in increased expression of CSE1L mRNA CTD PMID:24136188 NCBI chr 3:176,060,183...176,097,909
Ensembl chr 3:176,060,215...176,108,734 		JBrowse link
G Csf1 colony stimulating factor 1 decreases expression
multiple interactions
increases expression 		EXP
ISO 		nefazodone results in decreased expression of CSF1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CSF1 mRNA
nefazodone results in increased expression of CSF1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468 		JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP nefazodone results in decreased expression of CSF1R mRNA CTD PMID:24136188 NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP nefazodone results in decreased expression of CSRP1 mRNA CTD PMID:24136188 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:49,709,914...49,731,139 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP nefazodone results in decreased expression of CTH mRNA CTD PMID:24136188 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctsc cathepsin C decreases expression EXP nefazodone results in decreased expression of CTSC mRNA CTD PMID:24136188 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082 		JBrowse link
G Ctsd cathepsin D increases expression EXP nefazodone results in increased expression of CTSD mRNA CTD PMID:24136188 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821 		JBrowse link
G Ctsh cathepsin H decreases expression EXP nefazodone results in decreased expression of CTSH mRNA CTD PMID:24136188 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181 		JBrowse link
G Ctsl cathepsin L increases expression EXP nefazodone results in increased expression of CTSL mRNA CTD PMID:24136188 NCBI chr17:770,104...776,266
Ensembl chr17:770,093...777,113 		JBrowse link
G Cttn cortactin multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of CTTN mRNA CTD PMID:33819548 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression EXP nefazodone results in decreased expression of CXCL12 mRNA CTD PMID:24136188 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627 		JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression EXP nefazodone results in decreased expression of CXXC5 mRNA CTD PMID:24136188 NCBI chr18:27,701,650...27,732,633
Ensembl chr18:27,701,188...27,732,635 		JBrowse link
G Cyb5a cytochrome b5 type A increases expression EXP nefazodone results in increased expression of CYB5A mRNA CTD PMID:24136188 NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094 		JBrowse link
G Cybb cytochrome b-245 beta chain decreases expression EXP nefazodone results in decreased expression of CYBB mRNA CTD PMID:24136188 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of CYLD mRNA
nefazodone results in increased expression of CYLD mRNA 		CTD PMID:32152650 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity 		EXP
ISO 		nefazodone results in increased expression of CYP1A1 mRNA
nefazodone results in decreased activity of CYP1A1 protein 		CTD PMID:24136188 PMID:33814510 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of CYP1A2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP1A2 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO nefazodone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142 		JBrowse link
G Cyp20a1 cytochrome P450, family 20, subfamily a, polypeptide 1 increases expression EXP nefazodone results in increased expression of CYP20A1 mRNA CTD PMID:24136188 NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP27A1 mRNA CTD PMID:33819548 NCBI chr 9:83,712,402...83,743,222
Ensembl chr 9:83,713,293...83,743,215 		JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 increases expression EXP nefazodone results in increased expression of CYP2B12 mRNA CTD PMID:24136188 NCBI chr 1:91,135,294...91,147,094
Ensembl chr 1:91,135,294...91,208,159 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of CYP2B3 mRNA
nefazodone results in decreased expression of CYP2B6 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP2B6 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C18 mRNA CTD PMID:33819548 NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853 		JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP nefazodone results in decreased expression of CYP2C13 mRNA CTD PMID:24136188 NCBI chr 1:248,706,787...248,787,239
Ensembl chr 1:248,706,788...248,787,210 		JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 decreases expression EXP nefazodone results in decreased expression of CYP2C22 mRNA CTD PMID:24136188 NCBI chr 1:248,941,143...248,980,767
Ensembl chr 1:248,904,062...248,971,182 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP2C19 mRNA CTD PMID:33819548 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP nefazodone results in increased expression of CYP2E1 mRNA CTD PMID:24136188 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 decreases expression EXP nefazodone results in decreased expression of CYP2J3 mRNA CTD PMID:24136188 NCBI chr 5:116,335,755...116,360,677
Ensembl chr 5:116,335,755...116,360,499 		JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 decreases expression EXP nefazodone results in decreased expression of CYP2T1 mRNA CTD PMID:24136188 NCBI chr 1:91,573,923...91,579,215
Ensembl chr 1:91,574,572...91,579,215 		JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP nefazodone results in increased expression of CYP3A18 mRNA CTD PMID:24136188 NCBI chr12:13,994,312...14,044,185
Ensembl chr12:13,994,311...14,045,788 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
increases hydroxylation
multiple interactions
increases response to substance 		ISO nefazodone results in decreased expression of CYP3A4 mRNA
CYP3A4 protein results in increased hydroxylation of nefazodone
[CYP3A4 protein results in increased hydroxylation of nefazodone] which results in increased abundance of hydroxynefazodone; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP3A4 mRNA; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased hydroxylation of nefazodone]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]
CYP3A4 protein results in increased susceptibility to nefazodone 		CTD PMID:12584149 PMID:21540358 PMID:27485346 PMID:32152650 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases expression 		ISO
EXP 		nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]
nefazodone results in increased expression of CYP3A9 mRNA 		CTD PMID:12584149 PMID:24136188 NCBI chr12:21,919,955...21,960,160
Ensembl chr12:21,919,940...21,960,154 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP nefazodone results in increased expression of CYP4A1 mRNA CTD PMID:24136188 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP nefazodone results in increased expression of CYP4A3 mRNA CTD PMID:24136188 NCBI chr 5:134,334,396...134,352,268
Ensembl chr 5:134,334,701...134,352,236 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression EXP nefazodone results in decreased expression of CYP4F1 mRNA CTD PMID:24136188 NCBI chr 7:12,661,357...12,672,952
Ensembl chr 7:12,661,359...12,672,612 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 decreases expression EXP nefazodone results in decreased expression of CYP4F6 mRNA CTD PMID:24136188 NCBI chr 7:12,680,799...12,708,378
Ensembl chr 7:12,680,806...12,708,402 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
decreases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA
nefazodone results in decreased expression of CYP7A1 mRNA 		CTD PMID:32152650 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP7B1 mRNA CTD PMID:33819548 NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:102,419,011...102,451,804 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of CYP8B1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of CYP8B1 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:130,442,503...130,457,689 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression EXP nefazodone results in decreased expression of DAAM1 mRNA CTD PMID:24136188 NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049 		JBrowse link
G Dag1 dystroglycan 1 decreases expression EXP nefazodone results in decreased expression of DAG1 mRNA CTD PMID:24136188 NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:117,769,517...117,782,199 		JBrowse link
G Dao D-amino-acid oxidase increases expression EXP nefazodone results in increased expression of DAO mRNA CTD PMID:24136188 NCBI chr12:48,252,900...48,275,964
Ensembl chr12:48,252,902...48,273,300 		JBrowse link
G Dars1 aspartyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of DARS1 mRNA CTD PMID:24136188 NCBI chr13:42,410,351...42,465,467
Ensembl chr13:42,379,162...42,465,467 		JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 increases expression EXP nefazodone results in increased expression of DCAF11 mRNA CTD PMID:24136188 NCBI chr15:33,015,370...33,027,407
Ensembl chr15:33,016,762...33,027,672 		JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 increases expression EXP nefazodone results in increased expression of DCAF13 mRNA CTD PMID:24136188 NCBI chr 7:72,045,828...72,081,039
Ensembl chr 7:72,045,872...72,083,629 		JBrowse link
G Ddc dopa decarboxylase decreases expression EXP nefazodone results in decreased expression of DDC mRNA CTD PMID:24136188 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806 		JBrowse link
G Ddhd1 DDHD domain containing 1 decreases expression EXP nefazodone results in decreased expression of DDHD1 mRNA CTD PMID:24136188 NCBI chr15:21,304,053...21,370,608
Ensembl chr15:21,303,826...21,370,608 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions 		ISO nefazodone results in increased expression of DDIT3 mRNA; nefazodone results in increased expression of DDIT3 protein
2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; 4-phenylbutyric acid inhibits the reaction [nefazodone results in increased expression of DDIT3 protein]; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DDIT3 mRNA 		CTD PMID:24136188 PMID:27613715 PMID:32152650 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Ddx17 DEAD-box helicase 17 decreases expression EXP nefazodone results in decreased expression of DDX17 mRNA CTD PMID:24136188 NCBI chr 7:112,971,522...112,989,747
Ensembl chr 7:112,971,523...112,989,747 		JBrowse link
G Ddx21 DExD-box helicase 21 increases expression EXP nefazodone results in increased expression of DDX21 mRNA CTD PMID:24136188 NCBI chr20:31,077,044...31,097,238
Ensembl chr20:31,077,045...31,097,238 		JBrowse link
G Ddx39a DExD-box helicase 39A increases expression EXP nefazodone results in increased expression of DDX39A mRNA CTD PMID:24136188 NCBI chr19:41,323,465...41,331,413
Ensembl chr19:41,322,836...41,332,306 		JBrowse link
G Ddx56 DEAD-box helicase 56 increases expression EXP nefazodone results in increased expression of DDX56 mRNA CTD PMID:24136188 NCBI chr14:85,325,942...85,336,262
Ensembl chr14:85,325,942...85,336,262 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP nefazodone results in increased expression of DECR1 mRNA CTD PMID:24136188 NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:34,208,195...34,236,033 		JBrowse link
G Decr2 2,4-dienoyl-CoA reductase 2 increases expression EXP nefazodone results in increased expression of DECR2 mRNA CTD PMID:24136188 NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 increases expression EXP nefazodone results in increased expression of DEGS1 mRNA CTD PMID:24136188 NCBI chr13:96,478,645...96,485,302
Ensembl chr13:96,478,646...96,485,302 		JBrowse link
G Dennd4c DENN domain containing 4C increases expression EXP nefazodone results in increased expression of DENND4C mRNA CTD PMID:24136188 NCBI chr 5:106,316,942...106,421,484
Ensembl chr 5:106,318,281...106,415,489 		JBrowse link
G Desi1 desumoylating isopeptidase 1 increases expression EXP nefazodone results in increased expression of DESI1 mRNA CTD PMID:24136188 NCBI chr 7:115,401,613...115,422,974
Ensembl chr 7:115,401,624...115,423,172 		JBrowse link
G Desi2 desumoylating isopeptidase 2 increases expression EXP nefazodone results in increased expression of DESI2 mRNA CTD PMID:24136188 NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981 		JBrowse link
G Dexi Dexi homolog decreases expression EXP nefazodone results in decreased expression of DEXI mRNA CTD PMID:24136188 NCBI chr10:5,632,400...5,645,653
Ensembl chr10:5,632,961...5,645,648 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression EXP nefazodone results in increased expression of DGAT1 mRNA CTD PMID:24136188 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016 		JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP nefazodone results in decreased expression of DGKA mRNA CTD PMID:24136188 NCBI chr 7:1,733,247...1,761,181
Ensembl chr 7:1,733,248...1,759,569 		JBrowse link
G Dgkz diacylglycerol kinase zeta decreases expression EXP nefazodone results in decreased expression of DGKZ mRNA CTD PMID:24136188 NCBI chr 3:98,359,804...98,401,847
Ensembl chr 3:98,359,804...98,401,951 		JBrowse link
G Dhdds dehydrodolichyl diphosphate synthase subunit increases expression EXP nefazodone results in increased expression of DHDDS mRNA CTD PMID:24136188 NCBI chr 5:151,482,139...151,508,248
Ensembl chr 5:151,481,429...151,508,129 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 increases expression EXP nefazodone results in increased expression of DHRS4 mRNA CTD PMID:24136188 NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101 		JBrowse link
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 decreases expression EXP nefazodone results in decreased expression of DHTKD1 mRNA CTD PMID:24136188 NCBI chr17:77,242,512...77,316,074
Ensembl chr17:77,264,514...77,316,071 		JBrowse link
G Dhx15 DEAH-box helicase 15 increases expression EXP nefazodone results in increased expression of DHX15 mRNA CTD PMID:24136188 NCBI chr14:62,999,886...63,037,829
Ensembl chr14:62,999,877...63,037,828 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression EXP nefazodone results in increased expression of DIABLO mRNA CTD PMID:24136188 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein decreases expression EXP nefazodone results in decreased expression of DLC1 mRNA CTD PMID:24136188 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:61,995,001...62,374,819 		JBrowse link
G Dmgdh dimethylglycine dehydrogenase decreases expression EXP nefazodone results in decreased expression of DMGDH mRNA CTD PMID:24136188 NCBI chr 2:26,647,540...26,722,496
Ensembl chr 2:26,647,565...26,723,071 		JBrowse link
G Dnaaf9 dynein axonemal assembly factor 9 decreases expression EXP nefazodone results in decreased expression of DNAAF9 mRNA CTD PMID:24136188 NCBI chr 3:138,370,971...138,505,711
Ensembl chr 3:138,372,531...138,505,695 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 increases expression EXP nefazodone results in increased expression of DNAJA1 mRNA CTD PMID:24136188 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160 		JBrowse link
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 increases expression EXP nefazodone results in increased expression of DNAJA2 mRNA CTD PMID:24136188 NCBI chr19:37,671,019...37,689,163
Ensembl chr19:37,670,945...37,690,120 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 increases expression EXP nefazodone results in increased expression of DNAJA3 mRNA CTD PMID:24136188 NCBI chr10:11,361,168...11,386,599
Ensembl chr10:11,361,168...11,386,599 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of DNAJB1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB11 mRNA CTD PMID:32152650 NCBI chr11:91,656,334...91,672,800
Ensembl chr11:91,656,335...91,672,800 		JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression EXP nefazodone results in increased expression of DNAJB12 mRNA CTD PMID:24136188 NCBI chr20:28,371,180...28,389,390
Ensembl chr20:28,371,199...28,389,389 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of DNAJB9 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJB9 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJB9 mRNA 		CTD PMID:24136188 PMID:32152650 PMID:33819548 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344 		JBrowse link
G Dnajc1 DnaJ heat shock protein family (Hsp40) member C1 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC1 mRNA
nefazodone results in increased expression of DNAJC1 mRNA 		CTD PMID:32152650 NCBI chr17:85,863,651...86,020,954
Ensembl chr17:85,863,651...86,020,432 		JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC10 mRNA
nefazodone results in increased expression of DNAJC10 mRNA 		CTD PMID:32152650 NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:85,639,589...85,689,368 		JBrowse link
G Dnajc12 DnaJ heat shock protein family (Hsp40) member C12 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of DNAJC12 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of DNAJC12 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr20:25,245,475...25,266,238
Ensembl chr20:25,222,298...25,266,251 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 increases expression EXP nefazodone results in increased expression of DNAJC15 mRNA CTD PMID:24136188 NCBI chr15:59,594,314...59,658,862
Ensembl chr15:59,594,314...59,658,987 		JBrowse link
G Dnajc18 DnaJ heat shock protein family (Hsp40) member C18 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC18 mRNA CTD PMID:32152650 NCBI chr18:27,543,438...27,577,535
Ensembl chr18:27,543,438...27,577,535 		JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of DNAJC19 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC19 mRNA 		CTD PMID:32152650 NCBI chr 2:118,851,497...118,875,813
Ensembl chr 2:118,869,413...118,873,781 		JBrowse link
G Dnajc21 DnaJ heat shock protein family (Hsp40) member C21 multiple interactions
decreases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of DNAJC21 mRNA
nefazodone results in decreased expression of DNAJC21 mRNA 		CTD PMID:32152650 NCBI chr 2:61,146,669...61,173,908
Ensembl chr 2:61,145,142...61,174,126 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC3 mRNA CTD PMID:32152650 NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643 		JBrowse link
G Dnajc6 DnaJ heat shock protein family (Hsp40) member C6 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of DNAJC6 mRNA
nefazodone results in increased expression of DNAJC6 mRNA 		CTD PMID:32152650 NCBI chr 5:121,232,532...121,398,775
Ensembl chr 5:121,235,425...121,398,775 		JBrowse link
G Dnlz DNL-type zinc finger increases expression EXP nefazodone results in increased expression of DNLZ mRNA CTD PMID:24136188 NCBI chr 3:29,568,041...29,569,937
Ensembl chr 3:29,568,041...29,569,996 		JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 increases expression EXP nefazodone results in increased expression of DNPH1 mRNA CTD PMID:24136188 NCBI chr 9:21,978,894...21,981,631
Ensembl chr 9:21,978,894...21,981,631 		JBrowse link
G Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 increases expression EXP nefazodone results in increased expression of DNTTIP1 mRNA CTD PMID:24136188 NCBI chr 3:173,901,070...173,924,742
Ensembl chr 3:173,900,945...173,925,098 		JBrowse link
G Dock9 dedicator of cytokinesis 9 increases expression EXP nefazodone results in increased expression of DOCK9 mRNA CTD PMID:24136188 NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799 		JBrowse link
G Dohh deoxyhypusine hydroxylase increases expression EXP nefazodone results in increased expression of DOHH mRNA CTD PMID:24136188 NCBI chr 7:8,972,202...8,977,025
Ensembl chr 7:8,972,202...8,977,025 		JBrowse link
G Dph3 diphthamide biosynthesis 3 increases expression EXP nefazodone results in increased expression of DPH3 mRNA CTD PMID:24136188 NCBI chr16:7,294,580...7,299,996
Ensembl chr16:7,294,580...7,299,996 		JBrowse link
G Dpm1 dolichyl-phosphate mannosyltransferase subunit 1, catalytic increases expression EXP nefazodone results in increased expression of DPM1 mRNA CTD PMID:24136188 NCBI chr 3:177,338,855...177,358,398
Ensembl chr 3:177,338,855...177,358,412 		JBrowse link
G Dpy19l1 dpy-19 like C-mannosyltransferase 1 decreases expression EXP nefazodone results in decreased expression of DPY19L1 mRNA CTD PMID:24136188 NCBI chr 8:31,209,025...31,297,485
Ensembl chr 8:31,209,025...31,297,518 		JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit increases expression EXP nefazodone results in increased expression of DPY30 mRNA CTD PMID:24136188 NCBI chr 6:26,872,812...26,893,580
Ensembl chr 6:26,872,732...26,894,930 		JBrowse link
G Dpys dihydropyrimidinase decreases expression EXP nefazodone results in decreased expression of DPYS mRNA CTD PMID:24136188 NCBI chr 7:72,707,566...72,814,183
Ensembl chr 7:72,721,048...72,814,142 		JBrowse link
G Dr1 down-regulator of transcription 1 increases expression EXP nefazodone results in increased expression of DR1 mRNA CTD PMID:24136188 NCBI chr14:1,603,203...1,614,556
Ensembl chr14:1,603,204...1,614,556 		JBrowse link
G Dsc2 desmocollin 2 increases expression EXP nefazodone results in increased expression of DSC2 mRNA CTD PMID:24136188 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,725,466...11,757,466 		JBrowse link
G Dstn destrin, actin depolymerizing factor increases expression EXP nefazodone results in increased expression of DSTN mRNA CTD PMID:24136188 NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769 		JBrowse link
G Dtd1 D-aminoacyl-tRNA deacylase 1 increases expression EXP nefazodone results in increased expression of DTD1 mRNA CTD PMID:24136188 NCBI chr 3:152,449,193...152,611,960
Ensembl chr 3:152,452,620...152,486,304 		JBrowse link
G Dut deoxyuridine triphosphatase increases expression EXP nefazodone results in increased expression of DUT mRNA CTD PMID:24136188 NCBI chr 3:132,952,258...132,963,433
Ensembl chr 3:132,952,394...132,964,956 		JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 increases expression EXP nefazodone results in increased expression of DYNC1H1 mRNA CTD PMID:24136188 NCBI chr 6:135,436,375...135,502,117
Ensembl chr 6:135,430,750...135,502,116 		JBrowse link
G Dynll2 dynein light chain LC8-type 2 increases expression EXP nefazodone results in increased expression of DYNLL2 mRNA CTD PMID:24136188 NCBI chr10:73,264,260...73,283,042
Ensembl chr10:73,264,261...73,272,285 		JBrowse link
G Dynlt3 dynein light chain Tctex-type 3 decreases expression EXP nefazodone results in decreased expression of DYNLT3 mRNA CTD PMID:24136188 NCBI chr  X:16,000,425...16,009,632
Ensembl chr  X:16,000,395...16,009,627 		JBrowse link
G Ebna1bp2 EBNA1 binding protein 2 increases expression EXP nefazodone results in increased expression of EBNA1BP2 mRNA CTD PMID:24136188 NCBI chr 5:137,433,534...137,438,100
Ensembl chr 5:137,433,226...137,438,637 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase decreases expression EXP nefazodone results in decreased expression of EBP mRNA CTD PMID:24136188 NCBI chr  X:16,971,372...16,977,782
Ensembl chr  X:16,971,405...16,977,781 		JBrowse link
G Ebpl EBP like increases expression EXP nefazodone results in increased expression of EBPL mRNA CTD PMID:24136188 NCBI chr15:39,684,140...39,707,537
Ensembl chr15:39,684,140...39,707,537 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP nefazodone results in increased expression of ECH1 mRNA CTD PMID:24136188 NCBI chr 1:93,241,076...93,248,314
Ensembl chr 1:93,241,734...93,248,440 		JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression EXP nefazodone results in decreased expression of ECHDC1 mRNA CTD PMID:24136188 NCBI chr 1:30,304,968...30,355,957
Ensembl chr 1:30,304,971...30,337,208 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP nefazodone results in increased expression of ECI1 mRNA CTD PMID:24136188 NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773 		JBrowse link
G Ecm1 extracellular matrix protein 1 decreases expression EXP nefazodone results in decreased expression of ECM1 mRNA CTD PMID:24136188 NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606 		JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold increases expression EXP nefazodone results in increased expression of ECPAS mRNA CTD PMID:24136188 NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908 		JBrowse link
G Ecsit ECSIT signaling integrator increases expression EXP nefazodone results in increased expression of ECSIT mRNA CTD PMID:24136188 NCBI chr 8:28,881,594...28,894,443
Ensembl chr 8:28,881,594...28,894,397 		JBrowse link
G Eef1b2 eukaryotic translation elongation factor 1 beta 2 increases expression EXP nefazodone results in increased expression of EEF1B2 mRNA CTD PMID:24136188 NCBI chr 9:72,074,091...72,076,591
Ensembl chr 9:72,073,802...72,076,589 		JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta increases expression EXP nefazodone results in increased expression of EEF1D mRNA CTD PMID:24136188 NCBI chr 7:109,462,645...109,478,021
Ensembl chr 7:109,462,646...109,489,531 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 increases expression EXP nefazodone results in increased expression of EEF1E1 mRNA CTD PMID:24136188 NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,354,228...26,370,687 		JBrowse link
G Efna1 ephrin A1 decreases expression EXP nefazodone results in decreased expression of EFNA1 mRNA CTD PMID:24136188 NCBI chr 2:176,979,434...176,988,675
Ensembl chr 2:176,979,434...176,988,726 		JBrowse link
G Egf epidermal growth factor decreases expression EXP nefazodone results in decreased expression of EGF mRNA CTD PMID:24136188 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP nefazodone results in decreased expression of EGFR mRNA CTD PMID:24136188 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Ehbp1 EH domain binding protein 1 decreases expression EXP nefazodone results in decreased expression of EHBP1 mRNA CTD PMID:24136188 NCBI chr14:100,294,585...100,581,764
Ensembl chr14:100,294,585...100,546,579 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP nefazodone results in increased expression of EIF1A mRNA CTD PMID:24136188 NCBI chr18:41,512,298...41,524,645
Ensembl chr18:41,503,180...41,549,696 		JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing increases expression EXP nefazodone results in increased expression of EIF1AD mRNA CTD PMID:24136188 NCBI chr 1:212,103,715...212,109,015
Ensembl chr 1:212,103,892...212,109,017 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A multiple interactions
increases expression 		ISO 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [nefazodone results in increased expression of EIF2A protein modified form] CTD PMID:27613715 NCBI chr 2:144,911,247...144,944,705
Ensembl chr 2:144,911,153...144,945,201 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 decreases expression EXP nefazodone results in decreased expression of EIF2AK1 mRNA CTD PMID:24136188 NCBI chr12:15,824,431...15,858,266
Ensembl chr12:15,825,124...15,858,281 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon increases expression EXP nefazodone results in increased expression of EIF2B5 mRNA CTD PMID:24136188 NCBI chr11:93,898,814...93,909,431
Ensembl chr11:93,898,814...93,908,800 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression EXP nefazodone results in increased expression of EIF2S1 mRNA CTD PMID:24136188 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta increases expression EXP nefazodone results in increased expression of EIF2S2 mRNA CTD PMID:24136188 NCBI chr 3:163,834,846...163,855,733
Ensembl chr 3:163,834,851...163,855,570 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression EXP nefazodone results in increased expression of EIF2S3X mRNA CTD PMID:24136188 NCBI chr  X:62,910,292...62,933,936
Ensembl chr  X:62,910,293...62,934,489 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B increases expression EXP nefazodone results in increased expression of EIF3B mRNA CTD PMID:24136188 NCBI chr12:19,310,308...19,334,768
Ensembl chr12:19,310,311...19,334,939 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP nefazodone results in increased expression of EIF3C mRNA CTD PMID:24136188 NCBI chr 1:190,565,183...190,583,067
Ensembl chr 1:190,565,184...190,583,067 		JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E increases expression EXP nefazodone results in increased expression of EIF3E mRNA CTD PMID:24136188 NCBI chr 7:76,224,567...76,257,346
Ensembl chr 7:76,224,568...76,257,785 		JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G increases expression EXP nefazodone results in increased expression of EIF3G mRNA CTD PMID:24136188 NCBI chr 8:27,705,914...27,709,946
Ensembl chr 8:27,705,915...27,709,987 		JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I increases expression EXP nefazodone results in increased expression of EIF3I mRNA CTD PMID:24136188 NCBI chr 5:147,219,457...147,226,910
Ensembl chr 5:147,219,366...147,241,232 		JBrowse link
G Eif3l eukaryotic translation initiation factor 3, subunit L increases expression EXP nefazodone results in increased expression of EIF3L mRNA CTD PMID:24136188 NCBI chr 7:112,522,222...112,544,063
Ensembl chr 7:112,507,831...112,544,062 		JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M increases expression EXP nefazodone results in increased expression of EIF3M mRNA CTD PMID:24136188 NCBI chr 3:111,879,589...111,897,193
Ensembl chr 3:111,870,925...111,897,193 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression EXP nefazodone results in increased expression of EIF4A1 mRNA CTD PMID:24136188 NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,883,093...54,888,602 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E increases expression EXP nefazodone results in increased expression of EIF4E mRNA CTD PMID:24136188 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression EXP nefazodone results in increased expression of EIF4EBP1 mRNA CTD PMID:24136188 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 increases expression EXP nefazodone results in increased expression of EIF4EBP2 mRNA CTD PMID:24136188 NCBI chr20:29,922,260...29,942,922
Ensembl chr20:29,922,260...29,942,922 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 increases expression EXP nefazodone results in increased expression of EIF4G1 mRNA CTD PMID:24136188 NCBI chr11:93,726,322...93,746,387
Ensembl chr11:93,726,322...93,746,367 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression EXP nefazodone results in increased expression of EIF5 mRNA CTD PMID:24136188 NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP nefazodone results in increased expression of EIF5A mRNA CTD PMID:24136188 NCBI chr10:55,138,821...55,143,272
Ensembl chr10:55,138,823...55,143,330 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 increases expression EXP nefazodone results in increased expression of EIF6 mRNA CTD PMID:24136188 NCBI chr 3:164,785,162...164,791,410
Ensembl chr 3:164,785,163...164,791,525 		JBrowse link
G Elac2 elaC ribonuclease Z 2 increases expression EXP nefazodone results in increased expression of ELAC2 mRNA CTD PMID:24136188 NCBI chr10:50,131,449...50,154,755
Ensembl chr10:50,131,521...50,155,069 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 increases expression EXP nefazodone results in increased expression of ELAVL1 mRNA CTD PMID:24136188 NCBI chr12:7,441,699...7,482,625
Ensembl chr12:7,441,699...7,482,631 		JBrowse link
G Eloc elongin C increases expression EXP nefazodone results in increased expression of ELOC mRNA CTD PMID:24136188 NCBI chr 5:7,444,769...7,461,187
Ensembl chr20:25,752,857...25,753,279 		JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression EXP nefazodone results in increased expression of ELOVL2 mRNA CTD PMID:24136188 NCBI chr17:23,750,350...23,790,601
Ensembl chr17:23,750,350...23,790,601 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 decreases expression EXP nefazodone results in decreased expression of ELOVL5 mRNA CTD PMID:24136188 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Elp2 elongator acetyltransferase complex subunit 2 increases expression EXP nefazodone results in increased expression of ELP2 mRNA CTD PMID:24136188 NCBI chr18:16,160,686...16,196,307
Ensembl chr18:16,160,671...16,196,414 		JBrowse link
G Emc1 ER membrane protein complex subunit 1 increases expression EXP nefazodone results in increased expression of EMC1 mRNA CTD PMID:24136188 NCBI chr 5:156,891,773...156,917,092
Ensembl chr 5:156,891,773...156,917,092 		JBrowse link
G Emc10 ER membrane protein complex subunit 10 increases expression EXP nefazodone results in increased expression of EMC10 mRNA CTD PMID:24136188 NCBI chr 1:104,119,040...104,125,409
Ensembl chr 1:104,119,040...104,125,368 		JBrowse link
G Emc6 ER membrane protein complex subunit 6 increases expression EXP nefazodone results in increased expression of EMC6 mRNA CTD PMID:24136188 NCBI chr10:58,292,584...58,293,850
Ensembl chr10:58,292,470...58,298,885 		JBrowse link
G Emc7 ER membrane protein complex subunit 7 increases expression EXP nefazodone results in increased expression of EMC7 mRNA CTD PMID:24136188 NCBI chr 3:119,714,617...119,728,748
Ensembl chr 3:119,718,357...119,730,486 		JBrowse link
G Emc8 ER membrane protein complex subunit 8 increases expression EXP nefazodone results in increased expression of EMC8 mRNA CTD PMID:24136188 NCBI chr19:65,620,365...65,630,328
Ensembl chr19:65,620,375...65,630,235 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 decreases expression EXP nefazodone results in decreased expression of EMILIN1 mRNA CTD PMID:24136188 NCBI chr 6:31,175,919...31,183,657
Ensembl chr 6:31,175,919...31,183,657 		JBrowse link
G Eml4 EMAP like 4 decreases expression EXP nefazodone results in decreased expression of EML4 mRNA CTD PMID:24136188 NCBI chr 6:16,972,054...17,087,365
Ensembl chr 6:16,972,075...17,087,439 		JBrowse link
G Enc1 ectodermal-neural cortex 1 multiple interactions
decreases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of ENC1 mRNA
nefazodone results in decreased expression of ENC1 mRNA 		CTD PMID:32152650 NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 decreases expression EXP nefazodone results in decreased expression of ENPP1 mRNA CTD PMID:24136188 NCBI chr 1:22,518,051...22,583,044
Ensembl chr 1:22,518,069...22,583,044 		JBrowse link
G Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 increases expression EXP nefazodone results in increased expression of ENTPD4 mRNA CTD PMID:24136188 NCBI chr15:51,040,665...51,068,450
Ensembl chr15:51,040,673...51,068,441 		JBrowse link
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 increases expression EXP nefazodone results in increased expression of ENTPD5 mRNA CTD PMID:24136188 NCBI chr 6:109,750,210...109,786,376
Ensembl chr 6:109,753,204...109,786,495 		JBrowse link
G Entr1 endosome associated trafficking regulator 1 increases expression EXP nefazodone results in increased expression of ENTR1 mRNA CTD PMID:24136188 NCBI chr 3:29,599,059...29,605,780
Ensembl chr 3:29,599,059...29,605,898 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 increases expression EXP nefazodone results in increased expression of EPB41 mRNA CTD PMID:24136188 NCBI chr 5:149,394,080...149,548,178
Ensembl chr 5:149,394,096...149,543,540 		JBrowse link
G Epb41l4b erythrocyte membrane protein band 4.1 like 4B decreases expression EXP nefazodone results in decreased expression of EPB41L4B mRNA CTD PMID:24136188 NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of EPHX1 mRNA
nefazodone results in decreased expression of EPHX1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of EPRS1 mRNA CTD PMID:24136188 NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509 		JBrowse link
G Ereg epiregulin increases expression ISO nefazodone results in increased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Eri3 ERI1 exoribonuclease family member 3 increases expression EXP nefazodone results in increased expression of ERI3 mRNA CTD PMID:24136188 NCBI chr 5:136,252,691...136,379,832
Ensembl chr 5:136,252,683...136,379,815 		JBrowse link
G Erlin1 ER lipid raft associated 1 increases expression EXP nefazodone results in increased expression of ERLIN1 mRNA CTD PMID:24136188 NCBI chr 1:252,870,356...252,905,681
Ensembl chr 1:252,870,356...252,905,947 		JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression EXP nefazodone results in increased expression of ERMP1 mRNA CTD PMID:24136188 NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP nefazodone results in decreased expression of ERRFI1 mRNA CTD PMID:24136188 NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432 		JBrowse link
G Esd esterase D increases expression EXP nefazodone results in increased expression of ESD mRNA CTD PMID:24136188 NCBI chr15:56,453,082...56,472,582
Ensembl chr15:56,453,044...56,473,508 		JBrowse link
G Etf1 eukaryotic translation termination factor 1 increases expression EXP nefazodone results in increased expression of ETF1 mRNA CTD PMID:24136188 NCBI chr18:26,776,518...26,804,857
Ensembl chr18:26,777,858...26,804,613 		JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase decreases expression EXP nefazodone results in decreased expression of ETHE1 mRNA CTD PMID:24136188 NCBI chr 1:89,311,948...89,327,000
Ensembl chr 1:89,311,934...89,326,998 		JBrowse link
G Etnk1 ethanolamine kinase 1 increases expression EXP nefazodone results in increased expression of ETNK1 mRNA CTD PMID:24136188 NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721 		JBrowse link
G Exosc4 exosome component 4 increases expression EXP nefazodone results in increased expression of EXOSC4 mRNA CTD PMID:24136188 NCBI chr 7:109,928,491...109,931,233
Ensembl chr 7:109,928,498...109,931,820 		JBrowse link
G Exosc5 exosome component 5 increases expression EXP nefazodone results in increased expression of EXOSC5 mRNA CTD PMID:24136188 NCBI chr 1:90,295,495...90,305,047
Ensembl chr 1:90,293,797...90,305,046 		JBrowse link
G Exosc7 exosome component 7 increases expression EXP nefazodone results in increased expression of EXOSC7 mRNA CTD PMID:24136188 NCBI chr 8:131,650,988...131,676,399
Ensembl chr 8:131,651,050...131,696,825 		JBrowse link
G F10 coagulation factor X decreases expression EXP nefazodone results in decreased expression of F10 mRNA CTD PMID:24136188 NCBI chr16:83,170,973...83,190,280
Ensembl chr16:83,170,977...83,190,280 		JBrowse link
G Faah fatty acid amide hydrolase decreases expression EXP nefazodone results in decreased expression of FAAH mRNA CTD PMID:24136188 NCBI chr 5:134,716,545...134,735,396
Ensembl chr 5:134,716,545...134,735,396 		JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP nefazodone results in decreased expression of FABP5 mRNA CTD PMID:24136188 NCBI chr 2:93,672,451...93,676,186
Ensembl chr 2:93,672,458...93,676,127 		JBrowse link
G Fabp7 fatty acid binding protein 7 decreases expression EXP nefazodone results in decreased expression of FABP7 mRNA CTD PMID:24136188 NCBI chr20:37,667,125...37,673,299
Ensembl chr20:37,669,601...37,675,907 		JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP nefazodone results in decreased expression of FADS1 mRNA CTD PMID:24136188 NCBI chr 1:216,252,605...216,267,618
Ensembl chr 1:216,252,602...216,267,615 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression EXP nefazodone results in decreased expression of FADS2 mRNA CTD PMID:24136188 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Faf1 Fas associated factor 1 increases expression EXP nefazodone results in increased expression of FAF1 mRNA CTD PMID:24136188 NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516 		JBrowse link
G Fam117b family with sequence similarity 117, member B decreases expression EXP nefazodone results in decreased expression of FAM117B mRNA CTD PMID:24136188 NCBI chr 9:68,834,334...68,902,543
Ensembl chr 9:68,834,354...68,902,543 		JBrowse link
G Fam136a family with sequence similarity 136, member A increases expression EXP nefazodone results in increased expression of FAM136A mRNA CTD PMID:24136188 NCBI chr 4:120,362,563...120,368,479
Ensembl chr 4:120,362,561...120,368,479 		JBrowse link
G Fam193b family with sequence similarity 193, member B decreases expression EXP nefazodone results in decreased expression of FAM193B mRNA CTD PMID:24136188 NCBI chr17:9,071,974...9,104,659
Ensembl chr17:9,071,795...9,104,656 		JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A increases expression EXP nefazodone results in increased expression of FAM3A mRNA CTD PMID:24136188 NCBI chr  X:157,317,993...157,326,640
Ensembl chr  X:157,317,990...157,326,612 		JBrowse link
G Fam89a family with sequence similarity 89, member A decreases expression EXP nefazodone results in decreased expression of FAM89A mRNA CTD PMID:24136188 NCBI chr19:69,607,391...69,620,019
Ensembl chr19:69,607,391...69,620,019 		JBrowse link
G Fam91a1 family with sequence similarity 91, member A1 increases expression EXP nefazodone results in increased expression of FAM91A1 mRNA CTD PMID:24136188 NCBI chr 7:91,857,261...91,897,019
Ensembl chr 7:91,859,062...91,898,195 		JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta increases expression EXP nefazodone results in increased expression of FARSB mRNA CTD PMID:24136188 NCBI chr 9:87,336,321...87,395,546
Ensembl chr 9:87,336,326...87,395,505 		JBrowse link
G Fasn fatty acid synthase decreases expression EXP nefazodone results in decreased expression of FASN mRNA CTD PMID:24136188 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583 		JBrowse link
G Fbl fibrillarin increases expression EXP nefazodone results in increased expression of FBL mRNA CTD PMID:24136188 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506 		JBrowse link
G Fbxo21 F-box protein 21 increases expression EXP nefazodone results in increased expression of FBXO21 mRNA CTD PMID:24136188 NCBI chr12:44,231,918...44,266,035
Ensembl chr12:44,231,923...44,266,035 		JBrowse link
G Fbxo31 F-box protein 31 increases expression EXP nefazodone results in increased expression of FBXO31 mRNA CTD PMID:24136188 NCBI chr19:66,533,437...66,564,674
Ensembl chr19:66,533,437...66,564,674 		JBrowse link
G Fbxo4 F-box protein 4 increases expression EXP nefazodone results in increased expression of FBXO4 mRNA CTD PMID:24136188 NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388 		JBrowse link
G Fbxo7 F-box protein 7 increases expression EXP nefazodone results in increased expression of FBXO7 mRNA CTD PMID:24136188 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:19,696,961...19,725,180 		JBrowse link
G Fcf1 Fcf1 rRNA-processing protein increases expression EXP nefazodone results in increased expression of NOMO1 mRNA CTD PMID:24136188 NCBI chr 6:110,348,854...110,360,715
Ensembl chr 6:110,348,845...110,372,221 		JBrowse link
G Fcgr2a Fc gamma receptor 2A decreases expression EXP nefazodone results in decreased expression of FCGR2A mRNA CTD PMID:24136188 NCBI chr13:85,813,516...85,830,269
Ensembl chr13:85,855,437...85,864,394
Ensembl chr13:85,855,437...85,864,394 		JBrowse link
G Fcna ficolin A decreases expression EXP nefazodone results in decreased expression of FCNA mRNA CTD PMID:24136188 NCBI chr 3:28,844,036...28,847,441
Ensembl chr 3:28,844,039...28,847,237 		JBrowse link
G Fdx1 ferredoxin 1 increases expression EXP nefazodone results in increased expression of FDX1 mRNA CTD PMID:24136188 NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583 		JBrowse link
G Fech ferrochelatase increases expression EXP nefazodone results in increased expression of FECH mRNA CTD PMID:24136188 NCBI chr18:60,215,325...60,248,525
Ensembl chr18:60,215,325...60,249,546 		JBrowse link
G Fga fibrinogen alpha chain decreases expression EXP nefazodone results in decreased expression of FGA mRNA CTD PMID:24136188 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:170,672,012...170,679,577 		JBrowse link
G Fgb fibrinogen beta chain decreases expression EXP nefazodone results in decreased expression of FGB mRNA CTD PMID:24136188 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression EXP nefazodone results in increased expression of FGF21 mRNA CTD PMID:24136188 NCBI chr 1:105,219,825...105,221,376
Ensembl chr 1:105,219,825...105,232,056 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression EXP nefazodone results in decreased expression of FGFR2 mRNA CTD PMID:24136188 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914 		JBrowse link
G Fgg fibrinogen gamma chain decreases expression EXP nefazodone results in decreased expression of FGG mRNA CTD PMID:24136188 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170 		JBrowse link
G Fggy FGGY carbohydrate kinase domain containing decreases expression EXP nefazodone results in decreased expression of FGGY mRNA CTD PMID:24136188 NCBI chr 5:115,514,573...115,901,713
Ensembl chr 5:115,472,211...115,901,714 		JBrowse link
G Fgl1 fibrinogen-like 1 decreases expression EXP nefazodone results in decreased expression of FGL1 mRNA CTD PMID:24136188 NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 increases expression EXP nefazodone results in increased expression of FKBP11 mRNA CTD PMID:24136188 NCBI chr 7:131,750,828...131,757,784
Ensembl chr 7:131,750,672...131,770,123 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression EXP nefazodone results in increased expression of FKBP1A mRNA CTD PMID:24136188 NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233 		JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 increases expression EXP nefazodone results in increased expression of FKBP3 mRNA CTD PMID:24136188 NCBI chr 6:88,850,137...88,862,542
Ensembl chr 6:88,843,879...88,863,447 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of FKBP5 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FKBP5 mRNA 		CTD PMID:32152650 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,458,940...6,543,118 		JBrowse link
G Flcn folliculin increases expression EXP nefazodone results in increased expression of FLCN mRNA CTD PMID:24136188 NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309 		JBrowse link
G Flot1 flotillin 1 decreases expression EXP nefazodone results in decreased expression of FLOT1 mRNA CTD PMID:24136188 NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771 		JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 increases expression EXP nefazodone results in increased expression of FLYWCH1 mRNA CTD PMID:24136188 NCBI chr10:13,279,232...13,298,955
Ensembl chr10:13,279,232...13,298,925 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of FMO1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of FMO1 mRNA 		CTD PMID:32152650 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874 		JBrowse link
G Fn1 fibronectin 1 decreases expression EXP nefazodone results in decreased expression of FN1 mRNA CTD PMID:24136188 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fndc3b fibronectin type III domain containing 3B increases expression EXP nefazodone results in increased expression of FNDC3B mRNA CTD PMID:24136188 NCBI chr 2:112,240,108...112,546,113
Ensembl chr 2:112,243,202...112,546,306 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO nefazodone results in increased expression of FOS mRNA CTD PMID:27288927 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of FOSL1 mRNA
nefazodone results in increased expression of FOSL1 mRNA 		CTD PMID:32152650 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP nefazodone results in decreased expression of FOXA2 mRNA CTD PMID:24136188 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757 		JBrowse link
G Foxn3 forkhead box N3 decreases expression EXP nefazodone results in decreased expression of FOXN3 mRNA CTD PMID:24136188 NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040 		JBrowse link
G Foxo3 forkhead box O3 increases expression ISO nefazodone results in increased expression of FOXO3 mRNA CTD PMID:27288927 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Fstl1 follistatin-like 1 decreases expression EXP nefazodone results in decreased expression of FSTL1 mRNA CTD PMID:24136188 NCBI chr11:76,400,870...76,454,053
Ensembl chr11:76,391,315...76,455,126 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase increases expression EXP nefazodone results in increased expression of FTCD mRNA CTD PMID:24136188 NCBI chr20:12,054,710...12,068,219
Ensembl chr20:12,054,711...12,068,237 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP nefazodone results in increased expression of FTL1 mRNA CTD PMID:24136188 NCBI chr 1:105,072,858...105,074,705
Ensembl chr  X:45,399,355...45,399,915
Ensembl chr 2:45,399,355...45,399,915
Ensembl chr 1:45,399,355...45,399,915 		JBrowse link
G Fus Fus RNA binding protein decreases expression EXP nefazodone results in decreased expression of FUS mRNA CTD PMID:24136188 NCBI chr 1:192,007,011...192,020,887
Ensembl chr 1:192,007,006...192,020,884 		JBrowse link
G Fxr1 FMR1 autosomal homolog 1 increases expression EXP nefazodone results in increased expression of FXR1 mRNA CTD PMID:24136188 NCBI chr 2:118,812,287...118,865,813
Ensembl chr 2:118,811,980...118,867,027 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression EXP nefazodone results in decreased expression of FZD1 mRNA CTD PMID:24136188 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:30,247,228...30,833,176 		JBrowse link
G Fzd8 frizzled class receptor 8 decreases expression EXP nefazodone results in decreased expression of FZD8 mRNA CTD PMID:24136188 NCBI chr17:62,007,849...62,015,485
Ensembl chr17:62,007,627...62,015,961 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP nefazodone results in decreased expression of G6PC1 mRNA CTD PMID:24136188 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Gaa alpha glucosidase increases expression EXP nefazodone results in increased expression of GAA mRNA CTD PMID:24136188 NCBI chr10:105,028,106...105,045,365
Ensembl chr10:105,028,307...105,045,366 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP nefazodone results in increased expression of GADD45A mRNA CTD PMID:24136188 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Galk1 galactokinase 1 increases expression EXP nefazodone results in increased expression of GALK1 mRNA CTD PMID:24136188 NCBI chr10:101,742,067...101,746,244
Ensembl chr10:101,735,061...101,746,258 		JBrowse link
G Galm galactose mutarotase decreases expression EXP nefazodone results in decreased expression of GALM mRNA CTD PMID:24136188 NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:20,589,776...20,644,417 		JBrowse link
G Gars1 glycyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of GARS1 mRNA CTD PMID:24136188 NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876 		JBrowse link
G Gas5 growth arrest specific 5 increases expression EXP nefazodone results in increased expression of GAS5 mRNA CTD PMID:24136188 NCBI chr13:75,836,963...75,840,284 JBrowse link
G Gas6 growth arrest specific 6 decreases expression EXP nefazodone results in decreased expression of GAS6 mRNA CTD PMID:24136188 NCBI chr16:82,747,676...82,778,090
Ensembl chr16:82,747,345...82,778,088 		JBrowse link
G Gc GC, vitamin D binding protein decreases expression EXP nefazodone results in decreased expression of GC mRNA CTD PMID:24136188 NCBI chr14:18,916,255...18,951,670
Ensembl chr14:18,916,246...18,951,673 		JBrowse link
G Gcat glycine C-acetyltransferase decreases expression EXP nefazodone results in decreased expression of GCAT mRNA CTD PMID:24136188 NCBI chr 7:112,475,572...112,481,920
Ensembl chr 7:112,475,496...112,482,664 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP nefazodone results in increased expression of GCH1 mRNA CTD PMID:24136188 NCBI chr15:22,884,006...22,917,412
Ensembl chr15:22,884,006...22,917,412 		JBrowse link
G Gck glucokinase decreases expression EXP nefazodone results in decreased expression of GCK mRNA CTD PMID:24136188 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:84,999,020...85,040,949 		JBrowse link
G Gckr glucokinase regulator decreases expression EXP nefazodone results in decreased expression of GCKR mRNA CTD PMID:24136188 NCBI chr 6:30,765,071...30,795,627
Ensembl chr 6:30,765,075...30,795,627 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP nefazodone results in increased expression of GCLC mRNA CTD PMID:24136188 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP nefazodone results in increased expression of GCLM mRNA CTD PMID:24136188 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Gda guanine deaminase increases expression EXP nefazodone results in increased expression of GDA mRNA CTD PMID:24136188 NCBI chr 1:228,333,401...228,408,901
Ensembl chr 1:228,333,364...228,409,348 		JBrowse link
G Gde1 glycerophosphodiester phosphodiesterase 1 increases expression EXP nefazodone results in increased expression of GDE1 mRNA CTD PMID:24136188 NCBI chr 1:182,451,182...182,466,569
Ensembl chr 1:182,451,184...182,466,772 		JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 increases expression EXP nefazodone results in increased expression of GEMIN6 mRNA CTD PMID:24136188 NCBI chr 6:20,538,325...20,542,867
Ensembl chr 6:20,538,325...20,542,852 		JBrowse link
G Get4 guided entry of tail-anchored proteins factor 4 increases expression EXP nefazodone results in increased expression of GET4 mRNA CTD PMID:24136188 NCBI chr12:20,490,861...20,508,096
Ensembl chr12:20,490,861...20,555,240 		JBrowse link
G Ggh gamma-glutamyl hydrolase increases expression EXP nefazodone results in increased expression of GGH mRNA CTD PMID:24136188 NCBI chr 5:38,326,747...38,349,655
Ensembl chr 5:38,326,594...38,349,647 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GGT1 mRNA CTD PMID:33819548 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression EXP nefazodone results in increased expression of GHITM mRNA CTD PMID:24136188 NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,905,806...12,918,123 		JBrowse link
G Ghr growth hormone receptor decreases expression EXP nefazodone results in decreased expression of GHR mRNA CTD PMID:24136188 NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331 		JBrowse link
G Gjb1 gap junction protein, beta 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB1 mRNA CTD PMID:33819548 NCBI chr  X:70,541,845...70,549,776
Ensembl chr  X:70,541,862...70,549,843 		JBrowse link
G Gjb2 gap junction protein, beta 2 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of GJB2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GJB2 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr15:35,375,977...35,393,817
Ensembl chr15:35,375,692...35,393,877 		JBrowse link
G Gk glycerol kinase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GK mRNA CTD PMID:33819548 NCBI chr  X:54,106,708...54,189,940
Ensembl chr  X:54,112,214...54,196,701 		JBrowse link
G Gldc glycine decarboxylase decreases expression EXP nefazodone results in decreased expression of GLDC mRNA CTD PMID:24136188 NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:237,296,753...237,375,604 		JBrowse link
G Glrx glutaredoxin increases expression EXP nefazodone results in increased expression of GLRX mRNA CTD PMID:24136188 NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543 		JBrowse link
G Glrx2 glutaredoxin 2 increases expression EXP nefazodone results in increased expression of GLRX2 mRNA CTD PMID:24136188 NCBI chr13:58,032,199...58,055,061
Ensembl chr13:58,032,401...58,043,150 		JBrowse link
G Glrx3 glutaredoxin 3 increases expression EXP nefazodone results in increased expression of GLRX3 mRNA CTD PMID:24136188 NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:201,671,481...201,701,717 		JBrowse link
G Glrx5 glutaredoxin 5 increases expression EXP nefazodone results in increased expression of GLRX5 mRNA CTD PMID:24136188 NCBI chr 6:129,752,902...129,763,278
Ensembl chr 6:129,752,840...129,763,278 		JBrowse link
G Gls2 glutaminase 2 decreases expression EXP nefazodone results in decreased expression of GLS2 mRNA CTD PMID:24136188 NCBI chr 7:1,201,757...1,218,014
Ensembl chr 7:1,201,838...1,218,013 		JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression EXP nefazodone results in decreased expression of GLUD1 mRNA CTD PMID:24136188 NCBI chr16:9,646,569...9,680,215
Ensembl chr16:9,646,509...9,680,210 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP nefazodone results in decreased expression of GLUL mRNA CTD PMID:24136188 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520 		JBrowse link
G Glyatl2 glycine-N-acyltransferase-like 2 increases expression EXP nefazodone results in increased expression of GLYATL2 mRNA CTD PMID:24136188 NCBI chr 1:219,232,154...219,265,142
Ensembl chr 1:219,232,103...219,266,322 		JBrowse link
G Gm2a ganglioside GM2 activator decreases expression EXP nefazodone results in decreased expression of GM2A mRNA CTD PMID:24136188 NCBI chr10:39,719,919...39,732,452
Ensembl chr10:39,719,938...39,732,451 		JBrowse link
G Gmps guanine monophosphate synthase increases expression EXP nefazodone results in increased expression of GMPS mRNA CTD PMID:24136188 NCBI chr 2:150,587,824...150,641,564
Ensembl chr 2:150,587,854...150,648,986 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP nefazodone results in decreased expression of GNAI2 mRNA CTD PMID:24136188 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:117,167,045...117,187,622 		JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression EXP nefazodone results in increased expression of GNAI3 mRNA CTD PMID:24136188 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Gnas GNAS complex locus decreases expression EXP nefazodone results in decreased expression of GNAS mRNA CTD PMID:24136188 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase decreases expression EXP nefazodone results in decreased expression of GNE mRNA CTD PMID:24136188 NCBI chr 5:63,062,953...63,103,320
Ensembl chr 5:63,062,850...63,103,251 		JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP nefazodone results in increased expression of GNL3 mRNA CTD PMID:24136188 NCBI chr16:6,213,844...6,220,029
Ensembl chr16:6,213,871...6,219,845 		JBrowse link
G Gnl3l G protein nucleolar 3 like increases expression EXP nefazodone results in increased expression of GNL3L mRNA CTD PMID:24136188 NCBI chr  X:23,404,324...23,437,501
Ensembl chr  X:23,404,324...23,439,315 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression EXP nefazodone results in decreased expression of GNMT mRNA CTD PMID:24136188 NCBI chr 9:21,752,235...21,756,368
Ensembl chr 9:21,752,266...21,755,692 		JBrowse link
G Gns glucosamine (N-acetyl)-6-sulfatase decreases expression EXP nefazodone results in decreased expression of GNS mRNA CTD PMID:24136188 NCBI chr 7:58,774,625...58,808,650
Ensembl chr 7:58,774,625...58,808,650 		JBrowse link
G Golph3 golgi phosphoprotein 3 increases expression EXP nefazodone results in increased expression of GOLPH3 mRNA CTD PMID:24136188 NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:63,074,256...63,113,577 		JBrowse link
G Golt1a golgi transport 1A increases expression EXP nefazodone results in increased expression of GOLT1A mRNA CTD PMID:24136188 NCBI chr13:47,312,412...47,325,176
Ensembl chr13:47,322,002...47,325,175 		JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing increases expression EXP nefazodone results in increased expression of GOPC mRNA CTD PMID:24136188 NCBI chr20:32,270,314...32,319,635
Ensembl chr20:32,270,314...32,319,611 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases expression EXP nefazodone results in decreased expression of GOT1 mRNA CTD PMID:24136188 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871 		JBrowse link
G Gpat4 glycerol-3-phosphate acyltransferase 4 increases expression EXP nefazodone results in increased expression of GPAT4 mRNA CTD PMID:24136188 NCBI chr16:75,515,935...75,555,431
Ensembl chr16:75,521,640...75,557,847 		JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 increases expression EXP nefazodone results in increased expression of GPD1 mRNA CTD PMID:24136188 NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:132,721,915...132,730,368 		JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression EXP nefazodone results in increased expression of GPI mRNA CTD PMID:24136188 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression EXP nefazodone results in decreased expression of GPLD1 mRNA CTD PMID:24136188 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975 		JBrowse link
G Gprc5b G protein-coupled receptor, class C, group 5, member B multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of GPRC5B mRNA CTD PMID:33819548 NCBI chr 1:182,748,247...182,772,711
Ensembl chr 1:182,748,247...182,772,757 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP nefazodone results in decreased expression of GPX1 mRNA CTD PMID:24136188 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of GPX2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of GPX2 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GPX2 mRNA 		CTD PMID:32152650 PMID:33819548 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP nefazodone results in increased expression of GPX4 mRNA CTD PMID:24136188 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629 		JBrowse link
G Gramd2b GRAM domain containing 2B increases expression EXP nefazodone results in increased expression of GRAMD2B mRNA CTD PMID:24136188 NCBI chr18:52,082,128...52,180,056
Ensembl chr18:52,082,029...52,180,054 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP nefazodone results in increased expression of GRINA mRNA CTD PMID:24136188 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:109,843,196...109,846,042 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 increases expression EXP nefazodone results in increased expression of GRWD1 mRNA CTD PMID:24136188 NCBI chr 1:105,437,708...105,443,410
Ensembl chr 1:105,437,709...105,443,825 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP nefazodone results in increased expression of GSR mRNA CTD PMID:24136188 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gss glutathione synthetase increases expression EXP nefazodone results in increased expression of GSS mRNA CTD PMID:24136188 NCBI chr 3:164,508,005...164,538,343
Ensembl chr 3:164,508,005...164,538,306 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions
decreases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTA1 mRNA
nefazodone results in decreased expression of GSTA1 mRNA 		CTD PMID:32152650 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP nefazodone results in increased expression of GSTA2 mRNA CTD PMID:24136188 NCBI chr 8:88,064,829...88,077,168
Ensembl chr 8:88,064,616...88,077,092 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP nefazodone results in increased expression of GSTA3 mRNA CTD PMID:24136188 NCBI chr 9:31,154,989...31,180,653
Ensembl chr 9:31,154,989...31,180,654 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP nefazodone results in increased expression of GSTA4 mRNA CTD PMID:24136188 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of GSTM1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of GSTM2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM2 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 2:198,312,179...198,316,962 JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of GSTM4 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of GSTM4 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 2:198,356,114...198,373,487
Ensembl chr 2:198,358,744...198,373,638 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP nefazodone results in increased expression of GSTP1 mRNA CTD PMID:24136188 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Gstp3 glutathione S-transferase pi 3 decreases expression EXP nefazodone results in decreased expression of GSTP3 mRNA CTD PMID:24136188 NCBI chr 1:210,785,151...210,787,705
Ensembl chr 1:210,785,151...210,787,684 		JBrowse link
G Gstt3 glutathione S-transferase, theta 3 increases expression EXP nefazodone results in increased expression of GSTT3 mRNA CTD PMID:24136188 NCBI chr20:12,873,618...12,881,974
Ensembl chr20:12,874,374...12,881,973 		JBrowse link
G Gtf2b general transcription factor IIB increases expression EXP nefazodone results in increased expression of GTF2B mRNA CTD PMID:24136188 NCBI chr 2:234,427,734...234,446,043
Ensembl chr 2:234,427,637...234,446,049 		JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 increases expression EXP nefazodone results in increased expression of GTF2H1 mRNA CTD PMID:24136188 NCBI chr 1:106,457,692...106,485,729
Ensembl chr 1:106,457,394...106,485,727 		JBrowse link
G Gtf3a general transcription factor III A increases expression EXP nefazodone results in increased expression of GTF3A mRNA CTD PMID:24136188 NCBI chr12:13,250,643...13,258,587
Ensembl chr12:13,250,644...13,258,587 		JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP nefazodone results in decreased expression of GUCY1B2 mRNA CTD PMID:24136188 NCBI chr15:40,774,907...40,845,463
Ensembl chr15:40,774,906...40,845,463 		JBrowse link
G Gulo gulonolactone (L-) oxidase decreases expression EXP nefazodone results in decreased expression of GULO mRNA CTD PMID:24136188 NCBI chr15:44,381,226...44,403,314
Ensembl chr15:44,381,214...44,403,422 		JBrowse link
G Gusb glucuronidase, beta decreases expression EXP nefazodone results in decreased expression of GUSB mRNA CTD PMID:24136188 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G H1f0 H1.0 linker histone decreases expression EXP nefazodone results in decreased expression of H1F0 mRNA CTD PMID:24136188 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006 		JBrowse link
G H2az2 H2A.Z variant histone 2 decreases expression EXP nefazodone results in decreased expression of H2AZ2 mRNA CTD PMID:24136188 NCBI chr14:85,507,228...85,526,166
Ensembl chr14:85,507,228...85,526,207
Ensembl chr16:85,507,228...85,526,207 		JBrowse link
G H3f3b H3.3 histone B increases expression EXP nefazodone results in increased expression of H3F3B mRNA CTD PMID:24136188 NCBI chr10:101,755,404...101,764,616
Ensembl chr10:101,755,404...101,757,636 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression EXP nefazodone results in increased expression of HACD3 mRNA CTD PMID:24136188 NCBI chr 8:74,396,441...74,433,700
Ensembl chr 8:74,396,442...74,433,700 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha increases expression EXP nefazodone results in increased expression of HADHA mRNA CTD PMID:24136188 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP nefazodone results in increased expression of HADHB mRNA CTD PMID:24136188 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:31,873,404...31,907,835 		JBrowse link
G Hagh hydroxyacyl glutathione hydrolase decreases expression EXP nefazodone results in decreased expression of HAGH mRNA CTD PMID:24136188 NCBI chr10:14,379,400...14,394,046
Ensembl chr10:14,382,410...14,394,043 		JBrowse link
G Hal histidine ammonia lyase decreases expression EXP nefazodone results in decreased expression of HAL mRNA CTD PMID:24136188 NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:29,893,855...29,924,744 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP nefazodone results in decreased expression of HAMP mRNA CTD PMID:24136188 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP nefazodone results in decreased expression of HAO1 mRNA CTD PMID:24136188 NCBI chr 3:142,102,873...142,281,527
Ensembl chr 3:142,224,612...142,281,494 		JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP nefazodone results in decreased expression of HAO2 mRNA CTD PMID:24136188 NCBI chr 2:188,888,848...188,921,567
Ensembl chr 2:188,889,212...188,913,133 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of HARS1 mRNA CTD PMID:24136188 NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,655,671...28,672,712 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 decreases expression EXP nefazodone results in decreased expression of HBA-A1 mRNA CTD PMID:24136188 NCBI chr10:15,841,724...15,842,580
Ensembl chr10:15,841,763...15,842,603 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP nefazodone results in decreased expression of HBA1 mRNA CTD PMID:24136188 NCBI chr10:15,828,291...15,829,138
Ensembl chr10:15,828,377...15,829,141 		JBrowse link
G Hdac2 histone deacetylase 2 decreases expression EXP nefazodone results in decreased expression of HDAC2 mRNA CTD PMID:24136188 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:42,102,861...42,126,311 		JBrowse link
G Hdac6 histone deacetylase 6 increases expression EXP nefazodone results in increased expression of HDAC6 mRNA CTD PMID:24136188 NCBI chr  X:17,222,538...17,244,373
Ensembl chr  X:17,222,856...17,244,370 		JBrowse link
G Hdgf heparin binding growth factor increases expression EXP nefazodone results in increased expression of HDGF mRNA CTD PMID:24136188 NCBI chr 2:175,668,290...175,677,614
Ensembl chr 2:175,668,324...175,677,225 		JBrowse link
G Helz2 helicase with zinc finger 2 decreases expression EXP nefazodone results in decreased expression of HELZ2 mRNA CTD PMID:24136188 NCBI chr 3:188,716,370...188,730,776
Ensembl chr 3:188,716,370...188,730,716 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of HERPUD1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HERPUD1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP nefazodone results in decreased expression of HES6 mRNA CTD PMID:24136188 NCBI chr 9:99,449,375...99,451,343
Ensembl chr 9:99,449,371...99,451,096 		JBrowse link
G Hexa hexosaminidase subunit alpha decreases expression EXP nefazodone results in decreased expression of HEXA mRNA CTD PMID:24136188 NCBI chr 8:68,832,524...68,857,462
Ensembl chr 8:68,809,615...68,859,560 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 decreases expression EXP nefazodone results in decreased expression of HEXIM1 mRNA CTD PMID:24136188 NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,560,519...88,580,000 		JBrowse link
G Hfe homeostatic iron regulator increases expression EXP nefazodone results in increased expression of HFE mRNA CTD PMID:24136188 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase decreases expression EXP nefazodone results in decreased expression of HGD mRNA CTD PMID:24136188 NCBI chr11:76,592,202...76,643,776
Ensembl chr11:76,592,204...76,643,767 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HGF mRNA CTD PMID:33819548 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate increases expression EXP nefazodone results in increased expression of HGS mRNA CTD PMID:24136188 NCBI chr10:106,237,988...106,256,174
Ensembl chr10:106,237,824...106,256,174 		JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP nefazodone results in decreased expression of HHEX mRNA CTD PMID:24136188 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:244,602,825...244,608,604 		JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases expression EXP nefazodone results in increased expression of HIBCH mRNA CTD PMID:24136188 NCBI chr 9:56,082,082...56,161,796
Ensembl chr 9:56,082,091...56,161,886 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP nefazodone results in increased expression of HIGD1A mRNA CTD PMID:24136188 NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888 		JBrowse link
G Hikeshi heat shock protein nuclear import factor hikeshi increases expression EXP nefazodone results in increased expression of HIKESHI mRNA CTD PMID:24136188 NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911 		JBrowse link
G Hint2 histidine triad nucleotide binding protein 2 increases expression EXP nefazodone results in increased expression of HINT2 mRNA CTD PMID:24136188 NCBI chr 5:62,700,383...62,702,638
Ensembl chr 5:62,700,384...62,702,915 		JBrowse link
G Hlcs holocarboxylase synthetase increases expression EXP nefazodone results in increased expression of HLCS mRNA CTD PMID:24136188 NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082 		JBrowse link
G Hmbs hydroxymethylbilane synthase increases expression EXP nefazodone results in increased expression of HMBS mRNA CTD PMID:24136188 NCBI chr 8:53,570,364...53,577,758
Ensembl chr 8:53,570,364...53,577,802 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression EXP nefazodone results in increased expression of HMGCR mRNA CTD PMID:24136188 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression EXP nefazodone results in decreased expression of HMGCS1 mRNA CTD PMID:24136188 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 increases expression EXP nefazodone results in increased expression of HMGN1 mRNA CTD PMID:24136188 NCBI chr11:48,891,813...48,897,732
Ensembl chr11:48,891,814...48,897,771 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP nefazodone results in increased expression of HMOX1 mRNA CTD PMID:24136188 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression EXP nefazodone results in decreased expression of HNRNPA2B1 mRNA CTD PMID:24136188 NCBI chr 4:81,867,354...81,875,886
Ensembl chr 4:81,869,661...81,877,572 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression EXP nefazodone results in increased expression of HNRNPAB mRNA CTD PMID:24136188 NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307 		JBrowse link
G Hnrnpf heterogeneous nuclear ribonucleoprotein F increases expression EXP nefazodone results in increased expression of HNRNPF mRNA CTD PMID:24136188 NCBI chr 4:152,755,668...152,776,867
Ensembl chr 4:152,722,617...152,815,769 		JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 decreases expression EXP nefazodone results in decreased expression of HOGA1 mRNA CTD PMID:24136188 NCBI chr 1:250,806,430...250,833,544
Ensembl chr 1:250,806,255...250,833,869 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP nefazodone results in increased expression of HOMER1 mRNA CTD PMID:24136188 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression EXP nefazodone results in increased expression of HPRT1 mRNA CTD PMID:24136188 NCBI chr  X:137,655,744...137,687,718
Ensembl chr  X:137,655,680...137,687,712 		JBrowse link
G Hpx hemopexin multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of HPX mRNA CTD PMID:33819548 NCBI chr 1:169,344,647...169,352,155
Ensembl chr 1:169,344,583...169,352,156 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 increases expression EXP nefazodone results in increased expression of HSD17B4 mRNA CTD PMID:24136188 NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467 		JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP nefazodone results in decreased expression of HSD17B6 mRNA CTD PMID:24136188 NCBI chr 7:831,407...850,950
Ensembl chr 7:831,421...850,873 		JBrowse link
G Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 decreases expression EXP nefazodone results in decreased expression of HSD3B5 mRNA CTD PMID:24136188 NCBI chr 2:188,697,669...188,717,141
Ensembl chr 2:188,697,670...188,709,118 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 increases expression EXP nefazodone results in increased expression of HSDL2 mRNA CTD PMID:24136188 NCBI chr 5:79,238,881...79,274,051
Ensembl chr 5:79,212,525...79,274,798 		JBrowse link
G Hsf2 heat shock transcription factor 2 increases expression EXP nefazodone results in increased expression of HSF2 mRNA CTD PMID:24136188 NCBI chr20:37,366,301...37,393,922
Ensembl chr20:37,366,279...37,401,022 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP nefazodone results in increased expression of HSP90AA1 mRNA CTD PMID:24136188 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 increases expression EXP nefazodone results in increased expression of HSP90AB1 mRNA CTD PMID:24136188 NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of HSPA5 mRNA
nefazodone results in increased expression of HSPA5 mRNA 		CTD PMID:32152650 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP nefazodone results in increased expression of HSPA8 mRNA CTD PMID:24136188 NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP nefazodone results in increased expression of HSPA9 mRNA CTD PMID:24136188 NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,804,774...26,828,398 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP nefazodone results in increased expression of HSPB1 mRNA CTD PMID:24136188 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 increases expression EXP nefazodone results in increased expression of HSPB8 mRNA CTD PMID:24136188 NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 increases expression EXP nefazodone results in increased expression of HSPBP1 mRNA CTD PMID:24136188 NCBI chr 1:78,194,067...78,217,836
Ensembl chr 1:78,189,305...78,217,835 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP nefazodone results in increased expression of HSPD1 mRNA CTD PMID:24136188 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP nefazodone results in increased expression of HSPE1 mRNA CTD PMID:24136188 NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression EXP nefazodone results in increased expression of HSPH1 mRNA CTD PMID:24136188 NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression EXP nefazodone results in increased expression of HTATIP2 mRNA CTD PMID:24136188 NCBI chr 1:108,609,424...108,624,810
Ensembl chr 1:108,605,811...108,624,815 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A affects binding ISO nefazodone binds to HTR1A protein CTD PMID:7855217 NCBI chr 2:38,427,169...38,431,733
Ensembl chr 2:38,427,083...38,540,760 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding ISO nefazodone binds to HTR2C protein CTD PMID:18083778 NCBI chr  X:115,453,190...115,682,325
Ensembl chr  X:115,452,842...115,682,324 		JBrowse link
G Htra1 HtrA serine peptidase 1 decreases expression EXP nefazodone results in decreased expression of HTRA1 mRNA CTD PMID:24136188 NCBI chr 1:194,928,069...194,977,619
Ensembl chr 1:194,927,687...194,977,620 		JBrowse link
G Hyal3 hyaluronidase 3 decreases expression EXP nefazodone results in decreased expression of HYAL3 mRNA CTD PMID:24136188 NCBI chr 8:117,133,028...117,138,663
Ensembl chr 8:117,132,649...117,139,289 		JBrowse link
G Hycc2 hyccin PI4KA lipid kinase complex subunit 2 increases expression EXP nefazodone results in increased expression of HYCC2 mRNA CTD PMID:24136188 NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186 		JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of IARS1 mRNA CTD PMID:24136188 NCBI chr17:15,147,357...15,193,716
Ensembl chr17:15,147,357...15,193,652 		JBrowse link
G Iars2 isoleucyl-tRNA synthetase 2, mitochondrial increases expression EXP nefazodone results in increased expression of IARS2 mRNA CTD PMID:24136188 NCBI chr13:99,363,035...99,397,068
Ensembl chr13:99,362,696...99,397,068 		JBrowse link
G Iba57 iron-sulfur cluster assembly factor IBA57 increases expression EXP nefazodone results in increased expression of IBA57 mRNA CTD PMID:24136188 NCBI chr10:44,441,579...44,450,368
Ensembl chr10:44,441,579...44,450,368 		JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP nefazodone results in decreased expression of ICAM1 mRNA CTD PMID:24136188 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id4 inhibitor of DNA binding 4 decreases expression EXP nefazodone results in decreased expression of ID4 mRNA CTD PMID:24136188 NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492 		JBrowse link
G Ide insulin degrading enzyme increases expression EXP nefazodone results in increased expression of IDE mRNA CTD PMID:24136188 NCBI chr 1:244,415,495...244,516,925
Ensembl chr 1:244,416,343...244,514,526 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 increases expression EXP nefazodone results in increased expression of IDH1 mRNA CTD PMID:24136188 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:74,027,892...74,049,555 		JBrowse link
G Ier3 immediate early response 3 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of IER3 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IER3 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IFI27 mRNA CTD PMID:33819548 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781 		JBrowse link
G Ifi35 interferon-induced protein 35 increases expression EXP nefazodone results in increased expression of IFI35 mRNA CTD PMID:24136188 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 decreases expression EXP nefazodone results in decreased expression of IFITM1 mRNA CTD PMID:24136188 NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776 		JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP 		[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone CTD PMID:19362101 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 increases expression EXP nefazodone results in increased expression of IFRD1 mRNA CTD PMID:24136188 NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131 		JBrowse link
G Ifrd2 interferon-related developmental regulator 2 increases expression EXP nefazodone results in increased expression of IFRD2 mRNA CTD PMID:24136188 NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP nefazodone results in decreased expression of IGF1 mRNA CTD PMID:24136188 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP nefazodone results in decreased expression of IGFALS mRNA CTD PMID:24136188 NCBI chr10:14,397,076...14,408,439
Ensembl chr10:14,403,399...14,407,138 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of IGFBP1 mRNA CTD PMID:33819548 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 decreases expression EXP nefazodone results in decreased expression of IGFBP3 mRNA CTD PMID:24136188 NCBI chr14:86,270,208...86,277,944
Ensembl chr14:86,270,208...86,277,944 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression EXP nefazodone results in decreased expression of IGFBP4 mRNA CTD PMID:24136188 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP nefazodone results in decreased expression of IGFBP7 mRNA CTD PMID:24136188 NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620 		JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 increases expression EXP nefazodone results in increased expression of IGSF11 mRNA CTD PMID:24136188 NCBI chr11:75,238,706...75,389,748
Ensembl chr11:75,236,545...75,390,425 		JBrowse link
G Igsf5 immunoglobulin superfamily, member 5 decreases expression EXP nefazodone results in decreased expression of IGSF5 mRNA CTD PMID:24136188 NCBI chr11:49,155,990...49,198,872
Ensembl chr11:49,156,341...49,210,603 		JBrowse link
G Igtp interferon gamma induced GTPase decreases expression EXP nefazodone results in decreased expression of IGTP mRNA CTD PMID:24136188 NCBI chr10:42,875,047...42,882,866
Ensembl chr10:42,876,790...42,882,858 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 increases expression EXP nefazodone results in increased expression of IL13RA1 mRNA CTD PMID:24136188 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il17ra interleukin 17 receptor A decreases expression EXP nefazodone results in decreased expression of IL17RA mRNA CTD PMID:24136188 NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:155,339,400...155,362,382 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
decreases expression 		EXP
ISO 		[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone
nefazodone results in decreased expression of IL1A mRNA 		CTD PMID:19362101 PMID:32816093 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO nefazodone results in decreased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il24 interleukin 24 increases expression ISO nefazodone results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Il33 interleukin 33 decreases expression EXP nefazodone results in decreased expression of IL33 mRNA CTD PMID:24136188 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901 		JBrowse link
G Imp3 IMP U3 small nucleolar ribonucleoprotein 3 increases expression EXP nefazodone results in increased expression of IMP3 mRNA CTD PMID:24136188 NCBI chr 8:66,235,498...66,236,386 JBrowse link
G Imp4 IMP U3 small nucleolar ribonucleoprotein 4 increases expression EXP nefazodone results in increased expression of IMP4 mRNA CTD PMID:24136188 NCBI chr 9:44,150,029...44,155,167
Ensembl chr 9:44,150,337...44,157,751 		JBrowse link
G Impdh2 inosine monophosphate dehydrogenase 2 increases expression EXP nefazodone results in increased expression of IMPDH2 mRNA CTD PMID:24136188 NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873 		JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP nefazodone results in decreased expression of INHBA mRNA CTD PMID:24136188 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Inhbc inhibin subunit beta C decreases expression EXP nefazodone results in decreased expression of INHBC mRNA CTD PMID:24136188 NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:65,069,451...65,082,919 		JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP nefazodone results in increased expression of INMT mRNA CTD PMID:24136188 NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755 		JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP nefazodone results in decreased expression of INSIG1 mRNA CTD PMID:24136188 NCBI chr 4:8,049,339...8,057,812
Ensembl chr 4:8,049,556...8,057,778 		JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP nefazodone results in increased expression of INSIG2 mRNA CTD PMID:24136188 NCBI chr13:35,025,160...35,052,937
Ensembl chr13:35,025,164...35,047,658 		JBrowse link
G Ipmk inositol polyphosphate multikinase decreases expression EXP nefazodone results in decreased expression of IPMK mRNA CTD PMID:24136188 NCBI chr20:17,216,151...17,250,826
Ensembl chr20:17,216,151...17,250,757 		JBrowse link
G Ipo4 importin 4 increases expression EXP nefazodone results in increased expression of IPO4 mRNA CTD PMID:24136188 NCBI chr15:33,087,321...33,097,241
Ensembl chr15:33,087,321...33,097,241 		JBrowse link
G Ipo5 importin 5 increases expression EXP nefazodone results in increased expression of IPO5 mRNA CTD PMID:24136188 NCBI chr15:104,397,626...104,447,985
Ensembl chr15:104,397,276...104,447,985 		JBrowse link
G Ipo7 importin 7 increases expression EXP nefazodone results in increased expression of IPO7 mRNA CTD PMID:24136188 NCBI chr 1:173,497,472...173,537,707
Ensembl chr 1:173,497,503...173,536,778 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression EXP nefazodone results in increased expression of IRAK1 mRNA CTD PMID:24136188 NCBI chr  X:156,919,927...156,929,825
Ensembl chr  X:156,920,081...156,929,825 		JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression EXP nefazodone results in increased expression of IREB2 mRNA CTD PMID:24136188 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:64,154,945...64,205,520 		JBrowse link
G Irf6 interferon regulatory factor 6 decreases expression EXP nefazodone results in decreased expression of IRF6 mRNA CTD PMID:24136188 NCBI chr13:107,200,876...107,220,083
Ensembl chr13:107,200,731...107,220,049 		JBrowse link
G Irgm immunity-related GTPase M decreases expression EXP nefazodone results in decreased expression of IRGM mRNA CTD PMID:24136188 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,732,961...33,743,228 		JBrowse link
G Isoc1 isochorismatase domain containing 1 increases expression EXP nefazodone results in increased expression of ISOC1 mRNA CTD PMID:24136188 NCBI chr18:54,356,757...54,377,170
Ensembl chr18:54,356,734...54,377,170 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 decreases expression EXP nefazodone results in decreased expression of ITIH1 mRNA CTD PMID:24136188 NCBI chr16:6,128,696...6,142,813
Ensembl chr16:6,128,698...6,142,853 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 decreases expression EXP nefazodone results in decreased expression of ITIH2 mRNA CTD PMID:24136188 NCBI chr17:73,285,281...73,321,555
Ensembl chr17:73,285,270...73,321,547 		JBrowse link
G Ivd isovaleryl-CoA dehydrogenase decreases expression EXP nefazodone results in decreased expression of IVD mRNA CTD PMID:24136188 NCBI chr 3:126,305,584...126,326,016
Ensembl chr 3:126,305,364...126,328,160 		JBrowse link
G Iyd iodotyrosine deiodinase decreases expression EXP nefazodone results in decreased expression of IYD mRNA CTD PMID:24136188 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:42,410,130...42,426,386 		JBrowse link
G Jade1 jade family PHD finger 1 increases expression EXP nefazodone results in increased expression of JADE1 mRNA CTD PMID:24136188 NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252 		JBrowse link
G Jagn1 jagunal homolog 1 increases expression EXP nefazodone results in increased expression of JAGN1 mRNA CTD PMID:24136188 NCBI chr 4:148,147,213...148,151,915
Ensembl chr 4:148,147,229...148,151,915 		JBrowse link
G Jmjd1c jumonji domain containing 1C decreases expression EXP nefazodone results in decreased expression of JMJD1C mRNA CTD PMID:24136188 NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,330,990...21,461,916 		JBrowse link
G Josd1 Josephin domain containing 1 increases expression EXP nefazodone results in increased expression of JOSD1 mRNA CTD PMID:24136188 NCBI chr 7:113,110,709...113,124,632
Ensembl chr 7:113,110,717...113,124,632 		JBrowse link
G Josd2 Josephin domain containing 2 increases expression EXP nefazodone results in increased expression of JOSD2 mRNA CTD PMID:24136188 NCBI chr 1:104,097,382...104,101,271
Ensembl chr 1:104,097,376...104,101,277 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
increases expression 		EXP
ISO 		nefazodone results in decreased expression of JUN mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUN mRNA
nefazodone results in increased expression of JUN mRNA 		CTD PMID:24136188 PMID:27288927 PMID:32152650 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
increases expression 		EXP
ISO 		nefazodone results in decreased expression of JUND mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of JUND mRNA
nefazodone results in increased expression of JUND mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Jup junction plakoglobin decreases expression EXP nefazodone results in decreased expression of JUP mRNA CTD PMID:24136188 NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,800,814...85,827,429 		JBrowse link
G Kansl1 KAT8 regulatory NSL complex subunit 1 decreases expression EXP nefazodone results in decreased expression of KANSL1 mRNA CTD PMID:24136188 NCBI chr10:89,737,637...89,868,620
Ensembl chr10:89,737,637...89,868,620 		JBrowse link
G Kansl2 KAT8 regulatory NSL complex subunit 2 increases expression EXP nefazodone results in increased expression of KANSL2 mRNA CTD PMID:24136188 NCBI chr 7:131,548,062...131,564,876
Ensembl chr 7:131,548,062...131,564,753 		JBrowse link
G Kcmf1 potassium channel modulatory factor 1 increases expression EXP nefazodone results in increased expression of KCMF1 mRNA CTD PMID:24136188 NCBI chr 4:106,447,974...106,508,359
Ensembl chr 4:106,447,981...106,508,359 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
affects activity
multiple interactions 		ISO nefazodone results in decreased activity of KCNH2 protein
nefazodone affects the activity of KCNH2 protein
nefazodone binds to and results in decreased activity of KCNH2 protein 		CTD PMID:24052561 PMID:24374264 PMID:26821276 PMID:28551711 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 multiple interactions ISO nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr 3:60,353,990...60,518,110
Ensembl chr 3:60,354,146...60,518,104 		JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 multiple interactions ISO nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA] CTD PMID:22164246 NCBI chr 8:38,981,598...39,011,197
Ensembl chr 8:38,983,034...39,011,101 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 multiple interactions ISO nefazodone affects the activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA] CTD PMID:22164246 NCBI chr11:47,531,312...47,778,348
Ensembl chr11:47,531,312...47,778,348 		JBrowse link
G Kctd5 potassium channel tetramerization domain containing 5 increases expression EXP nefazodone results in increased expression of KCTD5 mRNA CTD PMID:24136188 NCBI chr10:13,583,781...13,609,762
Ensembl chr10:13,583,781...13,610,062 		JBrowse link
G Kctd9 potassium channel tetramerization domain containing 9 increases expression EXP nefazodone results in increased expression of KCTD9 mRNA CTD PMID:24136188 NCBI chr15:46,117,211...46,145,258
Ensembl chr15:46,117,874...46,145,266 		JBrowse link
G Kdm5b lysine demethylase 5B decreases expression EXP nefazodone results in decreased expression of KDM5B mRNA CTD PMID:24136188 NCBI chr13:48,554,367...48,625,721
Ensembl chr13:48,554,420...48,626,423 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 increases expression EXP nefazodone results in increased expression of KEAP1 mRNA CTD PMID:24136188 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042 		JBrowse link
G Klf15 KLF transcription factor 15 increases expression EXP nefazodone results in increased expression of KLF15 mRNA CTD PMID:24136188 NCBI chr 4:124,522,652...124,535,613
Ensembl chr 4:124,522,909...124,542,373 		JBrowse link
G Klhdc2 kelch domain containing 2 increases expression EXP nefazodone results in increased expression of KLHDC2 mRNA CTD PMID:24136188 NCBI chr 6:93,512,981...93,552,809
Ensembl chr 6:93,513,017...93,577,762 		JBrowse link
G Kmt2e lysine methyltransferase 2E decreases expression EXP nefazodone results in decreased expression of KMT2E mRNA CTD PMID:24136188 NCBI chr 4:12,550,570...12,655,329
Ensembl chr 4:12,550,570...12,619,721 		JBrowse link
G Kng1 kininogen 1 decreases expression EXP nefazodone results in decreased expression of KNG1 mRNA CTD PMID:24136188 NCBI chr11:91,317,354...91,340,148
Ensembl chr11:91,317,355...91,340,148 		JBrowse link
G Kng2 kininogen 2 decreases expression EXP nefazodone results in decreased expression of KNG2 mRNA CTD PMID:24136188 NCBI chr11:91,418,470...91,440,841
Ensembl chr11:91,414,207...91,441,259 		JBrowse link
G Kpna1 karyopherin subunit alpha 1 increases expression EXP nefazodone results in increased expression of KPNA1 mRNA CTD PMID:24136188 NCBI chr11:78,221,165...78,279,778
Ensembl chr11:78,222,884...78,267,067 		JBrowse link
G Krt18 keratin 18 increases expression EXP nefazodone results in increased expression of KRT18 mRNA CTD PMID:24136188 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848 		JBrowse link
G Krt8 keratin 8 increases expression EXP nefazodone results in increased expression of KRT8 mRNA CTD PMID:24136188 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:135,002,894...135,010,403 		JBrowse link
G Kxd1 KxDL motif containing 1 increases expression EXP nefazodone results in increased expression of KXD1 mRNA CTD PMID:24136188 NCBI chr16:18,929,316...18,950,239
Ensembl chr16:18,936,356...18,950,237 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases expression EXP nefazodone results in increased expression of KYAT1 mRNA CTD PMID:24136188 NCBI chr 3:33,857,407...33,891,153
Ensembl chr 3:33,857,743...33,890,642 		JBrowse link
G Kynu kynureninase decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of KYNU mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of KYNU mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014 		JBrowse link
G L3mbtl2 L3MBTL histone methyl-lysine binding protein 2 increases expression EXP nefazodone results in increased expression of L3MBTL2 mRNA CTD PMID:24136188 NCBI chr 7:115,066,427...115,087,625
Ensembl chr 7:115,066,486...115,087,598 		JBrowse link
G Lactb2 lactamase, beta 2 increases expression EXP nefazodone results in increased expression of LACTB2 mRNA CTD PMID:24136188 NCBI chr 5:10,352,165...10,374,928
Ensembl chr 5:10,352,154...10,379,255 		JBrowse link
G Lama3 laminin subunit alpha 3 increases expression EXP nefazodone results in increased expression of LAMA3 mRNA CTD PMID:24136188 NCBI chr18:3,797,898...4,033,021
Ensembl chr18:3,797,939...4,026,449 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression EXP nefazodone results in increased expression of LAMTOR3 mRNA CTD PMID:24136188 NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:229,084,858...229,099,383 		JBrowse link
G Lamtor4 late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 increases expression EXP nefazodone results in increased expression of LAMTOR4 mRNA CTD PMID:24136188 NCBI chr12:22,372,269...22,376,090
Ensembl chr12:22,372,269...22,376,090 		JBrowse link
G Lancl1 LanC like glutathione S-transferase 1 increases expression EXP nefazodone results in increased expression of LANCL1 mRNA CTD PMID:24136188 NCBI chr 9:75,968,284...75,998,397
Ensembl chr 9:75,968,286...76,003,475 		JBrowse link
G Lap3 leucine aminopeptidase 3 decreases expression EXP nefazodone results in decreased expression of LAP3 mRNA CTD PMID:24136188 NCBI chr14:69,820,907...69,839,891
Ensembl chr14:69,820,908...69,839,891 		JBrowse link
G Laptm4a lysosomal protein transmembrane 4 alpha increases expression EXP nefazodone results in increased expression of LAPTM4A mRNA CTD PMID:24136188 NCBI chr 6:37,438,503...37,456,238
Ensembl chr 6:37,438,121...37,456,223 		JBrowse link
G Lbp lipopolysaccharide binding protein multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of LBP mRNA CTD PMID:33819548 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 decreases expression EXP nefazodone results in decreased expression of LCMT1 mRNA CTD PMID:24136188 NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LDLR mRNA CTD PMID:33819548 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lect2 leukocyte cell-derived chemotaxin 2 decreases expression EXP nefazodone results in decreased expression of LECT2 mRNA CTD PMID:24136188 NCBI chr17:8,050,034...8,056,256
Ensembl chr17:8,050,034...8,056,256 		JBrowse link
G Leprotl1 leptin receptor overlapping transcript-like 1 increases expression EXP nefazodone results in increased expression of LEPROTL1 mRNA CTD PMID:24136188 NCBI chr16:64,744,148...64,756,776
Ensembl chr16:64,743,717...64,756,776 		JBrowse link
G Lgals5 galectin 5 decreases expression EXP nefazodone results in decreased expression of LGALS5 mRNA CTD PMID:24136188 NCBI chr10:64,351,976...64,355,137
Ensembl chr10:64,351,964...64,355,180 		JBrowse link
G Lgals8 galectin 8 increases expression EXP nefazodone results in increased expression of LGALS8 mRNA CTD PMID:24136188 NCBI chr17:62,716,368...62,744,272
Ensembl chr17:62,719,828...62,744,482 		JBrowse link
G Lgals9 galectin 9 decreases expression EXP nefazodone results in decreased expression of LGALS9 mRNA CTD PMID:24136188 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
G Lgalsl galectin-like decreases expression EXP nefazodone results in decreased expression of LGALSL mRNA CTD PMID:24136188 NCBI chr14:99,198,340...99,205,846
Ensembl chr14:99,198,339...99,206,487 		JBrowse link
G Lims2 LIM zinc finger domain containing 2 decreases expression EXP nefazodone results in decreased expression of LIMS2 mRNA CTD PMID:24136188 NCBI chr18:23,828,164...23,866,363
Ensembl chr18:23,837,686...23,867,086 		JBrowse link
G Lin37 lin-37 DREAM MuvB core complex component increases expression EXP nefazodone results in increased expression of LIN37 mRNA CTD PMID:24136188 NCBI chr 1:94,936,512...94,940,444
Ensembl chr 1:94,936,512...94,940,444 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression EXP nefazodone results in increased expression of LIPA mRNA CTD PMID:24136188 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740 		JBrowse link
G Lipc lipase C, hepatic type decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of LIPC mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of LIPC mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 8:80,390,470...80,516,463
Ensembl chr 8:80,390,471...80,516,285 		JBrowse link
G Lmbrd1 LMBR1 domain containing 1 increases expression EXP nefazodone results in increased expression of LMBRD1 mRNA CTD PMID:24136188 NCBI chr 9:34,592,723...34,674,425
Ensembl chr 9:34,577,616...34,674,428 		JBrowse link
G Lmna lamin A/C increases expression EXP nefazodone results in increased expression of LMNA mRNA CTD PMID:24136188 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072 		JBrowse link
G Lox lysyl oxidase decreases expression EXP nefazodone results in decreased expression of LOX mRNA CTD PMID:24136188 NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810 		JBrowse link
G Lpin1 lipin 1 decreases expression EXP nefazodone results in decreased expression of LPIN1 mRNA CTD PMID:24136188 NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991 		JBrowse link
G Lrat lecithin retinol acyltransferase decreases expression EXP nefazodone results in decreased expression of LRAT mRNA CTD PMID:24136188 NCBI chr 2:170,562,148...170,571,212
Ensembl chr 2:170,565,543...170,571,148 		JBrowse link
G Lrp1 LDL receptor related protein 1 decreases expression EXP nefazodone results in decreased expression of LRP1 mRNA CTD PMID:24136188 NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:65,265,639...65,346,196 		JBrowse link
G Lrp3 LDL receptor related protein 3 decreases expression EXP nefazodone results in decreased expression of LRP3 mRNA CTD PMID:24136188 NCBI chr 1:96,980,762...96,996,157
Ensembl chr 1:96,981,815...96,996,057 		JBrowse link
G Lrp5 LDL receptor related protein 5 decreases expression EXP nefazodone results in decreased expression of LRP5 mRNA CTD PMID:24136188 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:210,243,502...210,346,822 		JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression EXP nefazodone results in decreased expression of LRP6 mRNA CTD PMID:24136188 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:169,000,968...169,131,716 		JBrowse link
G Lrrc59 leucine rich repeat containing 59 increases expression EXP nefazodone results in increased expression of LRRC59 mRNA CTD PMID:24136188 NCBI chr10:80,069,162...80,083,820
Ensembl chr10:80,069,120...80,084,079 		JBrowse link
G Lrrc8b leucine rich repeat containing 8 VRAC subunit B decreases expression EXP nefazodone results in decreased expression of LRRC8B mRNA CTD PMID:24136188 NCBI chr14:4,655,273...4,721,648
Ensembl chr14:4,655,273...4,721,076 		JBrowse link
G Lsm10 LSM10, U7 small nuclear RNA associated increases expression EXP nefazodone results in increased expression of LSM10 mRNA CTD PMID:24136188 NCBI chr 5:143,649,817...143,660,391
Ensembl chr 5:143,615,360...143,663,986 		JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression EXP nefazodone results in decreased expression of LTA4H mRNA CTD PMID:24136188 NCBI chr 7:29,856,846...29,888,642
Ensembl chr 7:29,856,802...29,888,641 		JBrowse link
G Ltbr lymphotoxin beta receptor increases expression EXP nefazodone results in increased expression of LTBR mRNA CTD PMID:24136188 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:159,795,115...159,807,296 		JBrowse link
G Luc7l2 LUC7 pre-mRNA splicing factor like 2 decreases expression EXP nefazodone results in decreased expression of LUC7L2 mRNA CTD PMID:24136188 NCBI chr 4:68,251,435...68,314,861
Ensembl chr 4:68,271,414...68,314,837 		JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of LY96 mRNA CTD PMID:33819548 NCBI chr 5:7,365,536...7,397,864
Ensembl chr 5:7,365,557...7,395,816 		JBrowse link
G Lypla1 lysophospholipase 1 decreases expression EXP nefazodone results in decreased expression of LYPLA1 mRNA CTD PMID:24136188 NCBI chr 5:19,477,408...19,506,568
Ensembl chr 5:19,477,409...19,506,522 		JBrowse link
G Lyplal1 lysophospholipase-like 1 increases expression EXP nefazodone results in increased expression of LYPLAL1 mRNA CTD PMID:24136188 NCBI chr13:100,158,060...100,189,339
Ensembl chr13:100,158,060...100,189,503 		JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 decreases expression EXP nefazodone results in decreased expression of LYVE1 mRNA CTD PMID:24136188 NCBI chr 1:174,393,387...174,410,977 JBrowse link
G Maco1 macoilin 1 increases expression EXP nefazodone results in increased expression of MACO1 mRNA CTD PMID:24136188 NCBI chr 5:152,296,107...152,358,684
Ensembl chr 5:152,296,558...152,358,684 		JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 decreases expression EXP nefazodone results in decreased expression of MACROD1 mRNA CTD PMID:24136188 NCBI chr 1:213,675,413...213,831,571
Ensembl chr 1:213,675,406...213,816,348 		JBrowse link
G Maf MAF bZIP transcription factor multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAF mRNA CTD PMID:32152650 NCBI chr19:60,259,200...60,622,145
Ensembl chr19:60,269,541...60,621,378 		JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression EXP nefazodone results in decreased expression of MAFB mRNA CTD PMID:24136188 NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression
multiple interactions 		ISO nefazodone results in increased expression of MAFF mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFF mRNA 		CTD PMID:32152650 NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147 		JBrowse link
G Mafg MAF bZIP transcription factor G multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFG mRNA
nefazodone results in increased expression of MAFG mRNA 		CTD PMID:32152650 NCBI chr10:106,401,633...106,410,159 JBrowse link
G Mafk MAF bZIP transcription factor K increases expression
multiple interactions 		ISO nefazodone results in increased expression of MAFK mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAFK mRNA 		CTD PMID:32152650 NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192 		JBrowse link
G Magmas-ps1 mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction, pseudogene 1 increases expression EXP nefazodone results in increased expression of MAGMAS-PS1 mRNA CTD PMID:24136188 NCBI chr10:89,102,411...89,102,931 JBrowse link
G Magoh mago homolog, exon junction complex subunit increases expression EXP nefazodone results in increased expression of MAGOH mRNA CTD PMID:24136188 NCBI chr 5:127,868,044...127,875,423
Ensembl chr 5:127,868,055...127,875,384 		JBrowse link
G Mal2 mal, T-cell differentiation protein 2 increases expression EXP nefazodone results in increased expression of MAL2 mRNA CTD PMID:24136188 NCBI chr 7:87,790,239...87,823,219
Ensembl chr 7:87,790,239...87,850,403 		JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 increases expression EXP nefazodone results in increased expression of MALSU1 mRNA CTD PMID:24136188 NCBI chr 4:79,381,963...79,390,786
Ensembl chr 4:79,374,393...79,411,608 		JBrowse link
G Maoa monoamine oxidase A increases expression EXP nefazodone results in increased expression of MAOA mRNA CTD PMID:24136188 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of MAP1LC3B mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAP1LC3B mRNA; nefazodone results in increased expression of and results in increased lipidation of MAP1LC3B protein 		CTD PMID:24136188 PMID:32152650 PMID:33609687 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression EXP nefazodone results in increased expression of MAP2K1 mRNA CTD PMID:24136188 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases expression EXP nefazodone results in increased expression of MAP2K2 mRNA CTD PMID:24136188 NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 increases expression EXP nefazodone results in increased expression of MAP2K3 mRNA CTD PMID:24136188 NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MAP2K6 mRNA CTD PMID:32152650 NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of MAPK1 mRNA
nefazodone results in increased phosphorylation of and results in increased activity of MAPK1 protein 		CTD PMID:24136188 PMID:27613715 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO nefazodone results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:27613715 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 decreases expression EXP nefazodone results in decreased expression of MAPKAPK2 mRNA CTD PMID:24136188 NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326 		JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 increases expression
multiple interactions 		ISO nefazodone results in increased expression of MAPKAPK3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MAPKAPK3 mRNA 		CTD PMID:32152650 NCBI chr 8:116,808,429...116,842,228
Ensembl chr 8:116,808,429...116,842,228 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 increases expression EXP nefazodone results in increased expression of MARCHF5 mRNA CTD PMID:24136188 NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:244,343,630...244,366,462 		JBrowse link
G Marchf6 membrane associated ring-CH-type finger 6 increases expression EXP nefazodone results in increased expression of MARCHF6 mRNA CTD PMID:24136188 NCBI chr 2:84,166,570...84,243,817
Ensembl chr 2:84,166,570...84,243,792 		JBrowse link
G Marcksl1 MARCKS-like 1 decreases expression EXP nefazodone results in decreased expression of MARCKSL1 mRNA CTD PMID:24136188 NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:147,134,514...147,138,417 		JBrowse link
G Masp1 MBL associated serine protease 1 decreases expression EXP nefazodone results in decreased expression of MASP1 mRNA CTD PMID:24136188 NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470 		JBrowse link
G Mbl1 mannose binding lectin 1 decreases expression EXP nefazodone results in decreased expression of MBL1 mRNA CTD PMID:24136188 NCBI chr16:17,063,232...17,069,271
Ensembl chr16:17,060,703...17,069,271 		JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression EXP nefazodone results in decreased expression of MBL2 mRNA CTD PMID:24136188 NCBI chr 1:237,429,873...237,465,567
Ensembl chr 1:237,429,973...237,437,546 		JBrowse link
G Mbtd1 mbt domain containing 1 decreases expression EXP nefazodone results in decreased expression of MBTD1 mRNA CTD PMID:24136188 NCBI chr10:79,336,041...79,392,315
Ensembl chr10:79,335,235...79,392,315 		JBrowse link
G Mcee methylmalonyl CoA epimerase decreases expression EXP nefazodone results in decreased expression of MCEE mRNA CTD PMID:24136188 NCBI chr 1:127,376,311...127,399,551
Ensembl chr 1:127,376,298...127,400,367 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 increases expression EXP nefazodone results in increased expression of MCOLN1 mRNA CTD PMID:24136188 NCBI chr12:6,357,851...6,372,151
Ensembl chr12:6,357,807...6,372,151 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP nefazodone results in increased expression of MDM2 mRNA CTD PMID:24136188 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791 		JBrowse link
G Me1 malic enzyme 1 increases expression EXP nefazodone results in increased expression of ME1 mRNA CTD PMID:24136188 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275 		JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase increases expression EXP nefazodone results in increased expression of MECR mRNA CTD PMID:24136188 NCBI chr 5:149,313,765...149,339,964
Ensembl chr 5:149,313,774...149,342,825 		JBrowse link
G Med31 mediator complex subunit 31 increases expression EXP nefazodone results in increased expression of MED31 mRNA CTD PMID:24136188 NCBI chr10:57,335,507...57,338,889
Ensembl chr10:57,335,507...57,338,889 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase increases expression ISO nefazodone results in increased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Metap2 methionyl aminopeptidase 2 increases expression EXP nefazodone results in increased expression of METAP2 mRNA CTD PMID:24136188 NCBI chr 7:30,299,433...30,327,477
Ensembl chr 7:30,299,433...30,327,521 		JBrowse link
G Mettl5 methyltransferase 5, N6-adenosine increases expression EXP nefazodone results in increased expression of METTL5 mRNA CTD PMID:24136188 NCBI chr 3:75,033,605...75,046,359
Ensembl chr 3:75,026,861...75,045,831 		JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 increases expression EXP nefazodone results in increased expression of MFSD1 mRNA CTD PMID:24136188 NCBI chr 2:154,156,167...154,176,209
Ensembl chr 2:154,156,166...154,177,086 		JBrowse link
G Mfsd4b1 major facilitator superfamily domain containing 4B1 increases expression EXP nefazodone results in increased expression of MFSD4B1 mRNA CTD PMID:24136188 NCBI chr20:44,991,384...45,004,590
Ensembl chr20:44,991,384...45,006,161 		JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP nefazodone results in decreased expression of MGAT4B mRNA CTD PMID:24136188 NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309 		JBrowse link
G Mgll monoglyceride lipase increases expression EXP nefazodone results in increased expression of MGLL mRNA CTD PMID:24136188 NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440 		JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression
multiple interactions
decreases expression 		EXP
ISO 		nefazodone results in increased expression of MGST2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MGST2 mRNA; [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of MGST2 mRNA
nefazodone results in decreased expression of MGST2 mRNA 		CTD PMID:24136188 PMID:32152650 PMID:33819548 NCBI chr 2:137,821,787...137,866,664
Ensembl chr 2:137,836,140...137,866,661 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 decreases expression EXP nefazodone results in decreased expression of MGST3 mRNA CTD PMID:24136188 NCBI chr13:82,059,480...82,080,418
Ensembl chr13:82,059,480...82,080,575 		JBrowse link
G Mid1ip1 MID1 interacting protein 1 decreases expression EXP nefazodone results in decreased expression of MID1IP1 mRNA CTD PMID:24136188 NCBI chr  X:14,733,539...14,735,859
Ensembl chr  X:14,732,830...14,739,079 		JBrowse link
G Mif macrophage migration inhibitory factor increases expression EXP nefazodone results in increased expression of MIF mRNA CTD PMID:24136188 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Mindy3 MINDY lysine 48 deubiquitinase 3 decreases expression EXP nefazodone results in decreased expression of MINDY3 mRNA CTD PMID:24136188 NCBI chr17:80,454,404...80,532,999
Ensembl chr17:80,454,405...80,532,960 		JBrowse link
G Miox myo-inositol oxygenase increases expression EXP nefazodone results in increased expression of MIOX mRNA CTD PMID:24136188 NCBI chr 7:122,284,660...122,287,158
Ensembl chr 7:122,284,660...122,287,157 		JBrowse link
G Mix23 mitochondrial matrix import factor 23 increases expression EXP nefazodone results in increased expression of MIX23 mRNA CTD PMID:24136188 NCBI chr11:78,166,038...78,186,323
Ensembl chr11:78,166,038...78,186,323 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression EXP nefazodone results in decreased expression of MKNK2 mRNA CTD PMID:24136188 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529 		JBrowse link
G Mlec malectin increases expression EXP nefazodone results in increased expression of MLEC mRNA CTD PMID:24136188 NCBI chr12:47,118,918...47,133,598
Ensembl chr12:47,118,855...47,130,064 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of MLKL mRNA
nefazodone results in increased expression of MLKL mRNA 		CTD PMID:32152650 NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858 		JBrowse link
G Mlx MAX dimerization protein MLX increases expression EXP nefazodone results in increased expression of MLX mRNA CTD PMID:24136188 NCBI chr10:86,519,517...86,524,607
Ensembl chr10:86,519,864...86,524,772 		JBrowse link
G Mlxipl MLX interacting protein-like decreases expression EXP nefazodone results in decreased expression of MLXIPL mRNA CTD PMID:24136188 NCBI chr12:27,178,158...27,213,675
Ensembl chr12:27,178,158...27,213,660 		JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression EXP nefazodone results in increased expression of MLYCD mRNA CTD PMID:24136188 NCBI chr19:64,356,582...64,372,447
Ensembl chr19:64,356,223...64,372,446 		JBrowse link
G Mmadhc metabolism of cobalamin associated D increases expression EXP nefazodone results in increased expression of MMADHC mRNA CTD PMID:24136188 NCBI chr 3:55,117,832...55,135,735
Ensembl chr 3:55,117,833...55,135,851 		JBrowse link
G Mmgt1 membrane magnesium transporter 1 increases expression EXP nefazodone results in increased expression of MMGT1 mRNA CTD PMID:24136188 NCBI chr  X:139,445,834...139,458,169
Ensembl chr  X:139,445,834...139,458,169 		JBrowse link
G Mmut methylmalonyl-CoA mutase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MMUT mRNA CTD PMID:33819548 NCBI chr 9:27,425,935...27,454,202
Ensembl chr 9:27,425,935...27,454,342 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 increases expression EXP nefazodone results in increased expression of MOCS2 mRNA CTD PMID:24136188 NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394 		JBrowse link
G Morf4l2 mortality factor 4 like 2 increases expression EXP nefazodone results in increased expression of MORF4L2 mRNA CTD PMID:24136188 NCBI chr  X:104,874,850...104,885,946
Ensembl chr  X:104,852,693...104,892,855 		JBrowse link
G Mospd3 motile sperm domain containing 3 decreases expression EXP nefazodone results in decreased expression of MOSPD3 mRNA CTD PMID:24136188 NCBI chr12:24,728,012...24,737,078
Ensembl chr12:24,732,008...24,736,244 		JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 decreases expression EXP nefazodone results in decreased expression of MPC1 mRNA CTD PMID:24136188 NCBI chr 1:54,985,305...54,996,979
Ensembl chr 1:54,985,301...54,997,064 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 increases expression EXP nefazodone results in increased expression of MPC2 mRNA CTD PMID:24136188 NCBI chr13:80,261,143...80,280,668
Ensembl chr13:80,259,727...80,280,668 		JBrowse link
G Mpp1 MAGUK p55 scaffold protein 1 decreases expression EXP nefazodone results in decreased expression of MPP1 mRNA CTD PMID:24136188
G Mpst mercaptopyruvate sulfurtransferase decreases expression EXP nefazodone results in decreased expression of MPST mRNA CTD PMID:24136188 NCBI chr 7:111,836,079...111,843,651
Ensembl chr 7:111,835,587...111,843,650 		JBrowse link
G Mri1 methylthioribose-1-phosphate isomerase 1 increases expression EXP nefazodone results in increased expression of MRI1 mRNA CTD PMID:24136188 NCBI chr19:40,812,114...40,819,846
Ensembl chr19:40,812,094...40,822,607 		JBrowse link
G Mro maestro decreases expression EXP nefazodone results in decreased expression of MRO mRNA CTD PMID:24136188 NCBI chr18:69,723,764...69,742,815
Ensembl chr18:69,725,798...69,743,031 		JBrowse link
G Mrpl14 mitochondrial ribosomal protein L14 increases expression EXP nefazodone results in increased expression of MRPL14 mRNA CTD PMID:24136188 NCBI chr 9:22,800,286...22,812,711
Ensembl chr 9:22,795,744...22,812,855 		JBrowse link
G Mrpl17 mitochondrial ribosomal protein L17 increases expression EXP nefazodone results in increased expression of MRPL17 mRNA CTD PMID:24136188 NCBI chr 1:169,574,010...169,575,699
Ensembl chr 1:169,574,010...169,575,818 		JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 increases expression EXP nefazodone results in increased expression of MRPL18 mRNA CTD PMID:24136188 NCBI chr 1:50,384,951...50,389,769
Ensembl chr 1:50,384,367...50,389,763 		JBrowse link
G Mrpl19 mitochondrial ribosomal protein L19 increases expression EXP nefazodone results in increased expression of MRPL19 mRNA CTD PMID:24136188 NCBI chr 4:116,079,654...116,083,883
Ensembl chr 4:116,079,654...116,083,883 		JBrowse link
G Mrpl20 mitochondrial ribosomal protein L20 increases expression EXP nefazodone results in increased expression of MRPL20 mRNA CTD PMID:24136188 NCBI chr 5:171,690,664...171,695,728
Ensembl chr 5:171,691,198...171,695,728 		JBrowse link
G Mrpl22 mitochondrial ribosomal protein L22 increases expression EXP nefazodone results in increased expression of MRPL22 mRNA CTD PMID:24136188 NCBI chr10:42,843,165...42,856,243
Ensembl chr10:42,843,222...42,856,227 		JBrowse link
G Mrpl23 mitochondrial ribosomal protein L23 increases expression EXP nefazodone results in increased expression of MRPL23 mRNA CTD PMID:24136188 NCBI chr 1:207,116,930...207,124,702
Ensembl chr 1:207,116,462...207,124,699 		JBrowse link
G Mrpl24 mitochondrial ribosomal protein L24 increases expression EXP nefazodone results in increased expression of MRPL24 mRNA CTD PMID:24136188 NCBI chr 2:175,680,872...175,687,107
Ensembl chr 2:175,681,070...175,688,660 		JBrowse link
G Mrpl34 mitochondrial ribosomal protein L34 increases expression EXP nefazodone results in increased expression of MRPL34 mRNA CTD PMID:24136188 NCBI chr16:18,186,447...18,187,182
Ensembl chr16:18,185,306...18,187,181 		JBrowse link
G Mrpl36 mitochondrial ribosomal protein L36 increases expression EXP nefazodone results in increased expression of MRPL36 mRNA CTD PMID:24136188 NCBI chr 1:31,794,025...31,797,446
Ensembl chr 1:31,790,887...31,797,808 		JBrowse link
G Mrpl49 mitochondrial ribosomal protein L49 increases expression EXP nefazodone results in increased expression of MRPL49 mRNA CTD PMID:24136188 NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888 		JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 increases expression EXP nefazodone results in increased expression of MRPL50 mRNA CTD PMID:24136188 NCBI chr 5:68,662,933...68,668,087
Ensembl chr 5:68,662,939...68,669,748 		JBrowse link
G Mrpl52 mitochondrial ribosomal protein L52 increases expression EXP nefazodone results in increased expression of MRPL52 mRNA CTD PMID:24136188 NCBI chr15:31,852,927...31,856,160
Ensembl chr15:31,852,760...31,856,162 		JBrowse link
G Mrpl55 mitochondrial ribosomal protein L55 increases expression EXP nefazodone results in increased expression of MRPL55 mRNA CTD PMID:24136188 NCBI chr10:44,488,252...44,491,401
Ensembl chr10:44,488,244...44,491,401 		JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B increases expression EXP nefazodone results in increased expression of MRPS18B mRNA CTD PMID:24136188 NCBI chr20:2,842,978...2,849,065
Ensembl chr20:2,842,528...2,849,065 		JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C increases expression EXP nefazodone results in increased expression of MRPS18C mRNA CTD PMID:24136188 NCBI chr14:9,116,688...9,122,943 JBrowse link
G Mrps30 mitochondrial ribosomal protein S30 increases expression EXP nefazodone results in increased expression of MRPS30 mRNA CTD PMID:24136188 NCBI chr 2:52,189,049...52,196,136
Ensembl chr 2:52,189,058...52,195,904 		JBrowse link
G Mrps33 mitochondrial ribosomal protein S33 increases expression EXP nefazodone results in increased expression of MRPS33 mRNA CTD PMID:24136188 NCBI chr 4:69,563,501...69,572,317
Ensembl chr 4:69,563,503...69,572,177 		JBrowse link
G Mrps34 mitochondrial ribosomal protein S34 increases expression EXP nefazodone results in increased expression of MRPS34 mRNA CTD PMID:24136188 NCBI chr10:14,420,543...14,421,674
Ensembl chr10:14,408,136...14,421,771 		JBrowse link
G Mrps9 mitochondrial ribosomal protein S9 increases expression EXP nefazodone results in increased expression of MRPS9 mRNA CTD PMID:24136188 NCBI chr 9:52,605,678...52,664,499
Ensembl chr 9:52,605,678...52,664,499 		JBrowse link
G Mrto4 MRT4 homolog, ribosome maturation factor increases expression EXP nefazodone results in increased expression of MRTO4 mRNA CTD PMID:24136188 NCBI chr 5:156,884,985...156,891,738
Ensembl chr 5:156,884,985...156,891,738 		JBrowse link
G Msrb2 methionine sulfoxide reductase B2 increases expression EXP nefazodone results in increased expression of MSRB2 mRNA CTD PMID:24136188 NCBI chr17:86,882,750...86,908,392
Ensembl chr17:86,882,394...86,908,391 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 decreases expression ISO nefazodone results in decreased expression of ATP8 mRNA CTD PMID:27288927 NCBI chr MT:7,758...7,961
Ensembl chr MT:7,743...7,946 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I decreases expression ISO nefazodone results in decreased expression of COX1 mRNA CTD PMID:27288927 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853 		JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 decreases expression ISO nefazodone results in decreased expression of ND5 mRNA CTD PMID:27288927 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553 		JBrowse link
G Mt1a metallothionein 1A increases expression EXP nefazodone results in increased expression of MT1A mRNA CTD PMID:24136188 NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr  X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression EXP nefazodone results in decreased expression of MTARC1 mRNA CTD PMID:24136188 NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252 		JBrowse link
G Mterf3 mitochondrial transcription termination factor 3 increases expression EXP nefazodone results in increased expression of MTERF3 mRNA CTD PMID:24136188 NCBI chr 7:65,711,654...65,729,926
Ensembl chr 7:65,711,662...65,729,895 		JBrowse link
G Mthfs methenyltetrahydrofolate synthetase increases expression EXP nefazodone results in increased expression of MTHFS mRNA CTD PMID:24136188 NCBI chr 8:98,609,410...98,681,901
Ensembl chr 8:98,609,399...98,752,036 		JBrowse link
G Mtmr4 myotubularin related protein 4 increases expression EXP nefazodone results in increased expression of MTMR4 mRNA CTD PMID:24136188 NCBI chr10:72,890,665...72,913,598
Ensembl chr10:72,889,827...72,913,598 		JBrowse link
G Mtpn myotrophin increases expression EXP nefazodone results in increased expression of MTPN mRNA CTD PMID:24136188 NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 increases expression EXP nefazodone results in increased expression of MTSS1 mRNA CTD PMID:24136188 NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303 		JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of MTTP mRNA CTD PMID:33819548 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650 		JBrowse link
G Mug1 murinoglobulin 1 decreases expression EXP nefazodone results in decreased expression of MUG1 mRNA CTD PMID:24136188 NCBI chr 4:156,748,351...156,802,132 JBrowse link
G Mug2 murinoglobulin 2 decreases expression EXP nefazodone results in decreased expression of PZP mRNA CTD PMID:24136188 NCBI chr 4:156,836,140...156,908,972 JBrowse link
G Mvk mevalonate kinase decreases expression EXP nefazodone results in decreased expression of MVK mRNA CTD PMID:24136188 NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503 		JBrowse link
G Mybbp1a MYB binding protein 1a increases expression EXP nefazodone results in increased expression of MYBBP1A mRNA CTD PMID:24136188 NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,555,452...57,566,041 		JBrowse link
G Myh9 myosin, heavy chain 9 decreases expression EXP nefazodone results in decreased expression of MYH9 mRNA CTD PMID:24136188 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963 		JBrowse link
G Myo1d myosin ID decreases expression EXP nefazodone results in decreased expression of MYO1D mRNA CTD PMID:24136188 NCBI chr10:65,986,900...66,263,538
Ensembl chr10:65,975,122...66,263,958 		JBrowse link
G Myo1g myosin IG increases expression EXP nefazodone results in increased expression of MYO1G mRNA CTD PMID:24136188 NCBI chr14:85,600,619...85,615,760
Ensembl chr14:85,600,619...85,615,760 		JBrowse link
G Myorg myogenesis regulating glycosidase decreases expression EXP nefazodone results in decreased expression of MYORG mRNA CTD PMID:24136188 NCBI chr 5:61,452,956...61,460,500
Ensembl chr 5:61,432,418...61,460,581 		JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit increases expression EXP nefazodone results in increased expression of NAA15 mRNA CTD PMID:24136188 NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619 		JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit increases expression EXP nefazodone results in increased expression of NAA20 mRNA CTD PMID:24136188 NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit increases expression EXP nefazodone results in increased expression of NAA50 mRNA CTD PMID:24136188 NCBI chr11:70,044,281...70,066,754
Ensembl chr11:70,044,281...70,066,754 		JBrowse link
G Nab1 Ngfi-A binding protein 1 increases expression EXP nefazodone results in increased expression of NAB1 mRNA CTD PMID:24136188 NCBI chr 9:56,545,547...56,585,045
Ensembl chr 9:56,545,729...56,614,210 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 increases expression EXP nefazodone results in increased expression of NAE1 mRNA CTD PMID:24136188 NCBI chr19:452,462...478,591
Ensembl chr19:452,432...478,831 		JBrowse link
G Naga alpha-N-acetylgalactosaminidase decreases expression EXP nefazodone results in decreased expression of NAGA mRNA CTD PMID:24136188 NCBI chr 7:115,726,438...115,735,494
Ensembl chr 7:115,726,624...115,736,828 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP nefazodone results in increased expression of NAMPT mRNA CTD PMID:24136188 NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 increases expression EXP nefazodone results in increased expression of NAP1L1 mRNA CTD PMID:24136188 NCBI chr 7:48,819,464...48,844,108
Ensembl chr 7:48,819,477...48,844,104 		JBrowse link
G Napg NSF attachment protein gamma increases expression EXP nefazodone results in increased expression of NAPG mRNA CTD PMID:24136188 NCBI chr18:58,710,702...58,729,450
Ensembl chr18:58,708,655...58,729,450 		JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of NARS1 mRNA CTD PMID:24136188 NCBI chr18:60,259,506...60,275,782
Ensembl chr18:60,259,516...60,275,782 		JBrowse link
G Nat8 N-acetyltransferase 8 increases expression EXP nefazodone results in increased expression of NAT8 mRNA CTD PMID:24136188 NCBI chr 4:119,836,986...119,837,764
Ensembl chr 4:119,835,645...119,843,159 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 increases expression EXP nefazodone results in increased expression of NCBP1 mRNA CTD PMID:24136188 NCBI chr 5:65,211,632...65,244,532
Ensembl chr 5:65,211,358...65,244,665 		JBrowse link
G Nckap1 NCK-associated protein 1 increases expression EXP nefazodone results in increased expression of NCKAP1 mRNA CTD PMID:24136188 NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression EXP nefazodone results in decreased expression of NCOR1 mRNA CTD PMID:24136188 NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350 		JBrowse link
G Ndfip2 Nedd4 family interacting protein 2 increases expression EXP nefazodone results in increased expression of NDFIP2 mRNA CTD PMID:24136188 NCBI chr15:88,394,548...88,500,881
Ensembl chr15:88,395,032...88,503,600 		JBrowse link
G Ndrg2 NDRG family member 2 decreases expression EXP nefazodone results in decreased expression of NDRG2 mRNA CTD PMID:24136188 NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125 		JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 increases expression EXP nefazodone results in increased expression of NDUFA5 mRNA CTD PMID:24136188 NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235 		JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 increases expression EXP nefazodone results in increased expression of NDUFAB1 mRNA CTD PMID:24136188 NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:186,057,113...186,089,373 		JBrowse link
G Ndufaf3 NADH:ubiquinone oxidoreductase complex assembly factor 3 increases expression EXP nefazodone results in increased expression of NDUFAF3 mRNA CTD PMID:24136188 NCBI chr 8:118,139,891...118,141,723
Ensembl chr 8:118,139,892...118,141,723 		JBrowse link
G Ndufaf4 NADH:ubiquinone oxidoreductase complex assembly factor 4 increases expression EXP nefazodone results in increased expression of NDUFAF4 mRNA CTD PMID:24136188 NCBI chr 5:43,401,795...43,406,967 JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 increases expression EXP nefazodone results in increased expression of NDUFC2 mRNA CTD PMID:24136188 NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 decreases expression EXP nefazodone results in decreased expression of NDUFV3 mRNA CTD PMID:24136188 NCBI chr20:9,613,786...9,622,941
Ensembl chr13:48,468,224...48,488,847
Ensembl chr20:48,468,224...48,488,847 		JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression EXP nefazodone results in decreased expression of NECTIN3 mRNA CTD PMID:24136188 NCBI chr11:67,825,296...67,931,999
Ensembl chr11:67,827,137...67,871,383 		JBrowse link
G Net1 neuroepithelial cell transforming 1 decreases expression EXP nefazodone results in decreased expression of NET1 mRNA CTD PMID:24136188 NCBI chr17:71,251,145...71,280,345
Ensembl chr17:71,251,149...71,289,270 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression EXP nefazodone results in decreased expression of NFE2L2 mRNA CTD PMID:24136188 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfia nuclear factor I/A decreases expression EXP nefazodone results in decreased expression of NFIA mRNA CTD PMID:24136188 NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395 		JBrowse link
G Nfib nuclear factor I/B decreases expression EXP nefazodone results in decreased expression of NFIB mRNA CTD PMID:24136188 NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated decreases expression EXP nefazodone results in decreased expression of NFIL3 mRNA CTD PMID:24136188 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826 		JBrowse link
G Nfkbib NFKB inhibitor beta increases expression EXP nefazodone results in increased expression of NFKBIB mRNA CTD PMID:24136188 NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:93,173,820...93,326,366 		JBrowse link
G Nfu1 NFU1 iron-sulfur cluster scaffold increases expression EXP nefazodone results in increased expression of NFU1 mRNA CTD PMID:24136188 NCBI chr 4:121,016,316...121,036,925
Ensembl chr 4:121,016,393...121,037,493 		JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 increases expression EXP nefazodone results in increased expression of NFX1 mRNA CTD PMID:24136188 NCBI chr 5:60,900,140...60,958,889
Ensembl chr 5:60,901,217...60,958,889 		JBrowse link
G Nfxl1 nuclear transcription factor, X-box binding-like 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of NFXL1 mRNA CTD PMID:33819548 NCBI chr14:35,980,058...36,021,478
Ensembl chr14:35,980,057...36,023,281 		JBrowse link
G Nhp2 NHP2 ribonucleoprotein increases expression EXP nefazodone results in increased expression of NHP2 mRNA CTD PMID:24136188 NCBI chr10:36,378,020...36,381,362
Ensembl chr10:36,377,997...36,381,354 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 increases expression EXP nefazodone results in increased expression of NIFK mRNA CTD PMID:24136188 NCBI chr13:31,946,119...31,955,950
Ensembl chr13:31,946,108...31,959,561 		JBrowse link
G Nipsnap3b nipsnap homolog 3B decreases expression EXP nefazodone results in decreased expression of NIPSNAP3A mRNA CTD PMID:24136188 NCBI chr 5:72,446,945...72,465,090
Ensembl chr 5:72,432,957...72,465,544 		JBrowse link
G Nit1 nitrilase 1 increases expression EXP nefazodone results in increased expression of NIT1 mRNA CTD PMID:24136188 NCBI chr13:86,302,334...86,305,770
Ensembl chr13:86,298,387...86,305,770 		JBrowse link
G Nmt1 N-myristoyltransferase 1 increases expression EXP nefazodone results in increased expression of NMT1 mRNA CTD PMID:24136188 NCBI chr10:88,488,918...88,525,496
Ensembl chr10:88,488,990...88,522,729 		JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression EXP nefazodone results in decreased expression of NNMT mRNA CTD PMID:24136188 NCBI chr 8:57,820,156...57,851,301
Ensembl chr 8:57,825,464...57,843,174 		JBrowse link
G Nono non-POU domain containing, octamer-binding increases expression EXP nefazodone results in increased expression of NONO mRNA CTD PMID:24136188 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:70,593,888...70,611,979 		JBrowse link
G Nop16 NOP16 nucleolar protein increases expression EXP nefazodone results in increased expression of NOP16 mRNA CTD PMID:24136188 NCBI chr17:10,028,058...10,032,975
Ensembl chr17:10,028,034...10,033,038 		JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression EXP nefazodone results in increased expression of NOP56 mRNA CTD PMID:24136188 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959 		JBrowse link
G Notch2 notch receptor 2 decreases expression EXP nefazodone results in decreased expression of NOTCH2 mRNA CTD PMID:24136188 NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823 		JBrowse link
G Npepl1 aminopeptidase-like 1 increases expression EXP nefazodone results in increased expression of NPEPL1 mRNA CTD PMID:24136188 NCBI chr 3:183,312,185...183,324,744
Ensembl chr 3:183,312,185...183,324,744 		JBrowse link
G Nphp1 nephrocystin 1 increases expression EXP nefazodone results in increased expression of NPHP1 mRNA CTD PMID:24136188 NCBI chr 3:135,413,927...135,469,505
Ensembl chr 3:135,413,927...135,469,505 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor increases expression EXP nefazodone results in increased expression of NPLOC4 mRNA CTD PMID:24136188 NCBI chr10:106,152,756...106,208,306
Ensembl chr10:106,153,173...106,208,264 		JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP nefazodone results in increased expression of NPM1 mRNA CTD PMID:24136188 NCBI chr10:18,245,739...18,255,913
Ensembl chr10:18,245,740...18,256,024
Ensembl chr  X:18,245,740...18,256,024 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP nefazodone results in increased expression of NQO1 mRNA CTD PMID:24136188 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 decreases expression EXP nefazodone results in decreased expression of NQO2 mRNA CTD PMID:24136188 NCBI chr17:31,114,825...31,144,062
Ensembl chr17:31,114,529...31,143,662 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP nefazodone results in increased expression of NR1D2 mRNA CTD PMID:24136188 NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of NR1H2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of NR1H2 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:104,178,234...104,183,863 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of NR1H3 mRNA CTD PMID:33819548 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of NR1H4 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1H4 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 decreases expression ISO nefazodone results in decreased expression of NR1I2 mRNA CTD PMID:32152650 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
decreases expression 		EXP
ISO 		nefazodone results in increased expression of NR1I3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of NR1I3 mRNA
nefazodone results in decreased expression of NR1I3 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370 		JBrowse link
G Nr2c2ap nuclear receptor 2C2-associated protein increases expression EXP nefazodone results in increased expression of NR2C2AP mRNA CTD PMID:24136188 NCBI chr16:19,322,395...19,324,912
Ensembl chr16:19,322,405...19,324,637 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP nefazodone results in decreased expression of NR3C1 mRNA CTD PMID:24136188 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nrbp2 nuclear receptor binding protein 2 decreases expression EXP nefazodone results in decreased expression of NRBP2 mRNA CTD PMID:24136188 NCBI chr 7:109,679,330...109,685,656
Ensembl chr 7:109,679,330...109,685,588 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP nefazodone results in decreased expression of NREP mRNA CTD PMID:24136188 NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742 		JBrowse link
G Nsdhl NAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHL decreases expression EXP nefazodone results in decreased expression of NSDHL mRNA CTD PMID:24136188 NCBI chr  X:155,817,301...155,848,224
Ensembl chr  X:155,817,340...155,848,220 		JBrowse link
G Nsfl1c NSFL1 cofactor increases expression EXP nefazodone results in increased expression of NSFL1C mRNA CTD PMID:24136188 NCBI chr 3:160,438,708...160,463,261
Ensembl chr 3:160,438,708...160,463,228 		JBrowse link
G Nsmce1 NSE1 homolog, SMC5-SMC6 complex component increases expression EXP nefazodone results in increased expression of NSMCE1 mRNA CTD PMID:24136188 NCBI chr 1:189,462,801...189,489,188
Ensembl chr 1:189,462,677...189,491,432 		JBrowse link
G Nsun2 NOP2/Sun RNA methyltransferase 2 increases expression EXP nefazodone results in increased expression of NSUN2 mRNA CTD PMID:24136188 NCBI chr 1:35,490,583...35,514,839
Ensembl chr 1:35,490,583...35,514,306 		JBrowse link
G Nt5e 5' nucleotidase, ecto decreases expression EXP nefazodone results in decreased expression of NT5E mRNA CTD PMID:24136188 NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645 		JBrowse link
G Nubp2 NUBP iron-sulfur cluster assembly factor 2 increases expression EXP nefazodone results in increased expression of NUBP2 mRNA CTD PMID:24136188 NCBI chr10:14,407,743...14,411,428
Ensembl chr10:14,407,745...14,411,600 		JBrowse link
G Nucb2 nucleobindin 2 decreases expression EXP nefazodone results in decreased expression of NUCB2 mRNA CTD PMID:24136188 NCBI chr 1:180,185,121...180,221,644
Ensembl chr 1:180,199,551...180,230,116 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 increases expression EXP nefazodone results in increased expression of NUCKS1 mRNA CTD PMID:24136188 NCBI chr13:45,897,275...45,926,491
Ensembl chr13:45,897,248...45,923,101 		JBrowse link
G Nudc nuclear distribution C, dynein complex regulator increases expression EXP nefazodone results in increased expression of NUDC mRNA CTD PMID:24136188 NCBI chr 5:151,041,878...151,055,260
Ensembl chr 5:151,041,875...151,055,260 		JBrowse link
G Nudt4 nudix hydrolase 4 increases expression EXP nefazodone results in increased expression of NUDT4 mRNA CTD PMID:24136188 NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491 		JBrowse link
G Nudt7 nudix hydrolase 7 increases expression EXP nefazodone results in increased expression of NUDT7 mRNA CTD PMID:24136188 NCBI chr19:59,034,808...59,049,148
Ensembl chr19:59,034,839...59,063,994 		JBrowse link
G Nup153 nucleoporin 153 increases expression EXP nefazodone results in increased expression of NUP153 mRNA CTD PMID:24136188 NCBI chr17:18,178,434...18,231,109
Ensembl chr17:18,178,456...18,231,109 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP nefazodone results in increased expression of NUPR1 mRNA CTD PMID:24136188 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:190,643,867...190,645,901 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit increases expression EXP nefazodone results in increased expression of NUS1 mRNA CTD PMID:24136188 NCBI chr20:32,354,519...32,381,265
Ensembl chr20:32,354,439...32,381,264 		JBrowse link
G Nutf2 nuclear transport factor 2 increases expression EXP nefazodone results in increased expression of NUTF2 mRNA CTD PMID:24136188 NCBI chr19:50,662,168...50,683,457
Ensembl chr19:50,662,394...50,683,454 		JBrowse link
G Nxpe4 neurexophilin and PC-esterase domain family member 4 decreases expression EXP nefazodone results in decreased expression of NXPE4 mRNA CTD PMID:24136188 NCBI chr 8:57,399,199...57,640,629
Ensembl chr 8:57,631,895...57,644,186 		JBrowse link
G Oaf out at first homolog decreases expression EXP nefazodone results in decreased expression of OAF mRNA CTD PMID:24136188 NCBI chr 8:52,491,314...52,509,285
Ensembl chr 8:52,491,315...52,509,285 		JBrowse link
G Oat ornithine aminotransferase decreases expression EXP nefazodone results in decreased expression of OAT mRNA CTD PMID:24136188 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP nefazodone results in increased expression of ODC1 mRNA CTD PMID:24136188 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression EXP nefazodone results in decreased expression of OGT mRNA CTD PMID:24136188 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:70,811,319...70,856,123 		JBrowse link
G Olr59 olfactory receptor 59 decreases expression EXP nefazodone results in decreased expression of OLR59 mRNA CTD PMID:24136188 NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265 		JBrowse link
G Onecut1 one cut homeobox 1 decreases expression EXP nefazodone results in decreased expression of ONECUT1 mRNA CTD PMID:24136188 NCBI chr 8:84,480,066...84,507,848
Ensembl chr 8:84,480,305...84,508,124 		JBrowse link
G Onecut2 one cut homeobox 2 decreases expression EXP nefazodone results in decreased expression of ONECUT2 mRNA CTD PMID:24136188 NCBI chr18:60,101,967...60,161,095
Ensembl chr18:60,102,126...60,107,668 		JBrowse link
G Osbp oxysterol binding protein increases expression EXP nefazodone results in increased expression of OSBP mRNA CTD PMID:24136188 NCBI chr 1:218,313,455...218,343,263
Ensembl chr 1:218,313,148...218,343,258 		JBrowse link
G Osbpl11 oxysterol binding protein-like 11 increases expression EXP nefazodone results in increased expression of OSBPL11 mRNA CTD PMID:24136188 NCBI chr11:81,038,759...81,121,887
Ensembl chr11:81,038,985...81,101,299 		JBrowse link
G Otc ornithine transcarbamylase decreases expression EXP nefazodone results in decreased expression of OTC mRNA CTD PMID:24136188 NCBI chr  X:15,126,358...15,202,473
Ensembl chr  X:15,126,358...15,239,555 		JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 increases expression EXP nefazodone results in increased expression of OTUB1 mRNA CTD PMID:24136188 NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679 		JBrowse link
G Ovca2 OVCA2 serine hydrolase domain containing increases expression EXP nefazodone results in increased expression of OVCA2 mRNA CTD PMID:24136188 NCBI chr10:60,524,385...60,527,547
Ensembl chr10:60,522,026...60,527,536 		JBrowse link
G Oxnad1 oxidoreductase NAD-binding domain containing 1 increases expression EXP nefazodone results in increased expression of OXNAD1 mRNA CTD PMID:24136188 NCBI chr16:7,299,755...7,328,824
Ensembl chr16:7,299,755...7,328,824 		JBrowse link
G Pa2g4 proliferation-associated 2G4 increases expression EXP nefazodone results in increased expression of PA2G4 mRNA CTD PMID:24136188 NCBI chr 7:1,569,326...1,576,794
Ensembl chr 7:1,569,327...1,576,802 		JBrowse link
G Pabpn1 poly(A) binding protein, nuclear 1 decreases expression EXP nefazodone results in decreased expression of PABPN1 mRNA CTD PMID:24136188 NCBI chr15:32,337,955...32,342,700
Ensembl chr15:32,338,089...32,342,691 		JBrowse link
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 increases expression EXP nefazodone results in increased expression of PACSIN2 mRNA CTD PMID:24136188 NCBI chr 7:116,385,571...116,478,609
Ensembl chr 7:116,384,190...116,478,537 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression EXP nefazodone results in increased expression of PAFAH1B1 mRNA CTD PMID:24136188 NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196 		JBrowse link
G Pah phenylalanine hydroxylase multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PAH mRNA CTD PMID:33819548 NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627 		JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase increases expression EXP nefazodone results in increased expression of PAICS mRNA CTD PMID:24136188 NCBI chr14:31,553,355...31,586,843
Ensembl chr14:31,553,357...31,587,027 		JBrowse link
G Pald1 phosphatase domain containing, paladin 1 increases expression EXP nefazodone results in increased expression of PALD1 mRNA CTD PMID:24136188 NCBI chr20:29,812,650...29,877,733
Ensembl chr20:29,812,650...29,850,063 		JBrowse link
G Palmd palmdelphin decreases expression EXP nefazodone results in decreased expression of PALMD mRNA CTD PMID:24136188 NCBI chr 2:207,574,413...207,626,239
Ensembl chr 2:207,574,249...207,626,239 		JBrowse link
G Paox polyamine oxidase increases expression EXP nefazodone results in increased expression of PAOX mRNA CTD PMID:24136188 NCBI chr 1:204,349,326...204,358,140
Ensembl chr 1:204,348,987...204,358,481 		JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression EXP nefazodone results in decreased expression of PAQR9 mRNA CTD PMID:24136188 NCBI chr 8:104,993,884...104,996,180
Ensembl chr 8:104,993,827...104,998,285 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 decreases expression EXP nefazodone results in decreased expression of PARP14 mRNA CTD PMID:24136188 NCBI chr11:78,408,134...78,440,201
Ensembl chr11:78,408,058...78,440,195 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 decreases expression EXP nefazodone results in decreased expression of PARP9 mRNA CTD PMID:24136188 NCBI chr11:78,286,282...78,320,409
Ensembl chr11:78,286,287...78,320,608 		JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP nefazodone results in increased expression of PBLD1 mRNA CTD PMID:24136188 NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 decreases expression EXP nefazodone results in decreased expression of PBXIP1 mRNA CTD PMID:24136188 NCBI chr 2:177,154,056...177,167,810
Ensembl chr 2:177,154,101...177,167,328 		JBrowse link
G Pc pyruvate carboxylase decreases expression EXP nefazodone results in decreased expression of PC mRNA CTD PMID:24136188 NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 increases expression EXP nefazodone results in increased expression of PCBP1 mRNA CTD PMID:24136188 NCBI chr 4:120,530,100...120,532,107
Ensembl chr 4:120,529,172...120,539,111 		JBrowse link
G Pcdh1 protocadherin 1 decreases expression EXP nefazodone results in decreased expression of PCDH1 mRNA CTD PMID:24136188 NCBI chr18:30,258,154...30,290,828
Ensembl chr18:30,258,154...30,290,436 		JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 decreases expression EXP nefazodone results in decreased expression of PCDHGC3 mRNA CTD PMID:24136188 NCBI chr18:29,884,245...29,919,095 JBrowse link
G Pcgf6 polycomb group ring finger 6 increases expression EXP nefazodone results in increased expression of PCGF6 mRNA CTD PMID:24136188 NCBI chr 1:255,866,709...255,886,306
Ensembl chr 1:255,866,711...255,886,266 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP nefazodone results in decreased expression of PCK1 mRNA CTD PMID:24136188 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 increases expression EXP nefazodone results in increased expression of PCMT1 mRNA CTD PMID:24136188 NCBI chr 1:3,932,161...3,980,751
Ensembl chr 1:3,932,161...3,964,848 		JBrowse link
G Pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 decreases expression EXP nefazodone results in decreased expression of PCMTD1 mRNA CTD PMID:24136188 NCBI chr 5:17,071,629...17,143,803
Ensembl chr 5:17,071,629...17,142,010 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO nefazodone results in decreased expression of PCNA mRNA CTD PMID:27288927 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcnx1 pecanex 1 decreases expression EXP nefazodone results in decreased expression of PCNX1 mRNA CTD PMID:24136188 NCBI chr 6:107,296,704...107,433,576
Ensembl chr 6:107,296,792...107,432,452 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP nefazodone results in increased expression of PCSK6 mRNA CTD PMID:24136188 NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128 		JBrowse link
G Pctp phosphatidylcholine transfer protein decreases expression EXP nefazodone results in decreased expression of PCTP mRNA CTD PMID:24136188 NCBI chr10:75,305,999...75,351,919
Ensembl chr10:75,305,999...75,326,432 		JBrowse link
G Pdap1 PDGFA associated protein 1 increases expression EXP nefazodone results in increased expression of PDAP1 mRNA CTD PMID:24136188 NCBI chr12:14,584,414...14,594,641
Ensembl chr12:14,584,398...14,594,641 		JBrowse link
G Pdcd11 programmed cell death 11 increases expression EXP nefazodone results in increased expression of PDCD11 mRNA CTD PMID:24136188 NCBI chr 1:255,922,198...255,963,336
Ensembl chr 1:255,922,225...255,963,336 		JBrowse link
G Pdcd4 programmed cell death 4 decreases expression EXP nefazodone results in decreased expression of PDCD4 mRNA CTD PMID:24136188 NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189 		JBrowse link
G Pdcl3 phosducin-like 3 increases expression EXP nefazodone results in increased expression of PDCL3 mRNA CTD PMID:24136188 NCBI chr 9:48,730,083...48,738,554
Ensembl chr 9:48,723,767...48,739,529 		JBrowse link
G Pde2a phosphodiesterase 2A decreases expression EXP nefazodone results in decreased expression of PDE2A mRNA CTD PMID:24136188 NCBI chr 1:165,235,623...165,327,466
Ensembl chr 1:165,235,623...165,327,466 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 increases expression EXP nefazodone results in increased expression of PDHA1 mRNA CTD PMID:24136188 NCBI chr  X:38,509,158...38,522,986
Ensembl chr  X:38,509,084...38,522,536 		JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X increases expression EXP nefazodone results in increased expression of PDHX mRNA CTD PMID:24136188 NCBI chr 3:109,826,579...109,886,869
Ensembl chr 3:109,827,209...109,886,905 		JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 decreases expression EXP nefazodone results in decreased expression of PDIA5 mRNA CTD PMID:24136188 NCBI chr11:78,777,436...78,892,370
Ensembl chr11:78,777,419...78,864,329 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 decreases expression EXP nefazodone results in decreased expression of PDK2 mRNA CTD PMID:24136188 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 decreases expression EXP nefazodone results in decreased expression of PDK4 mRNA CTD PMID:24136188 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP nefazodone results in decreased expression of PDLIM1 mRNA CTD PMID:24136188 NCBI chr 1:248,991,818...249,040,409
Ensembl chr 1:248,991,818...249,047,379 		JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression EXP nefazodone results in increased expression of PDZK1 mRNA CTD PMID:24136188 NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression EXP nefazodone results in increased expression of PEBP1 mRNA CTD PMID:24136188 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780 		JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase increases expression EXP nefazodone results in increased expression of PECR mRNA CTD PMID:24136188 NCBI chr 9:81,347,170...81,375,809
Ensembl chr 9:81,347,173...81,375,806 		JBrowse link
G Pef1 penta-EF hand domain containing 1 increases expression EXP nefazodone results in increased expression of PEF1 mRNA CTD PMID:24136188 NCBI chr 5:147,735,973...147,759,239
Ensembl chr 5:147,735,976...147,761,092 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor increases expression EXP nefazodone results in increased expression of PELO mRNA CTD PMID:24136188 NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression EXP nefazodone results in increased expression of PEX11A mRNA CTD PMID:24136188 NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:143,089,410...143,096,645 		JBrowse link
G Pex16 peroxisomal biogenesis factor 16 increases expression EXP nefazodone results in increased expression of PEX16 mRNA CTD PMID:24136188 NCBI chr 3:98,800,357...98,808,091
Ensembl chr 3:98,798,654...98,808,630 		JBrowse link
G Pex2 peroxisomal biogenesis factor 2 increases expression EXP nefazodone results in increased expression of PEX2 mRNA CTD PMID:24136188 NCBI chr 2:97,957,479...97,973,767
Ensembl chr 2:97,948,443...97,981,092 		JBrowse link
G Pex7 peroxisomal biogenesis factor 7 increases expression EXP nefazodone results in increased expression of PEX7 mRNA CTD PMID:24136188 NCBI chr 1:16,402,319...16,466,304
Ensembl chr 1:16,402,320...16,466,366 		JBrowse link
G Pfdn6 prefoldin subunit 6 increases expression EXP nefazodone results in increased expression of PFDN6 mRNA CTD PMID:24136188 NCBI chr20:4,947,844...4,949,318
Ensembl chr20:4,947,844...4,949,318 		JBrowse link
G Pfn1 profilin 1 increases expression EXP nefazodone results in increased expression of PFN1 mRNA CTD PMID:24136188 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,863,881...55,868,611 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression EXP nefazodone results in increased expression of PGAM1 mRNA CTD PMID:24136188 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203 		JBrowse link
G Pgpep1 pyroglutamyl-peptidase I decreases expression EXP nefazodone results in decreased expression of PGPEP1 mRNA CTD PMID:24136188 NCBI chr16:18,804,408...18,817,466
Ensembl chr16:18,805,009...18,817,462 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression EXP nefazodone results in increased expression of PGRMC1 mRNA CTD PMID:24136188 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805 		JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 decreases expression EXP nefazodone results in decreased expression of PGRMC2 mRNA CTD PMID:24136188 NCBI chr 2:125,996,190...126,012,090
Ensembl chr 2:125,996,193...126,012,090 		JBrowse link
G Phb1 prohibitin 1 increases expression EXP nefazodone results in increased expression of PHB1 mRNA CTD PMID:24136188 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:81,102,028...81,116,233 		JBrowse link
G Phf5a PHD finger protein 5A increases expression EXP nefazodone results in increased expression of PHF5A mRNA CTD PMID:24136188 NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP nefazodone results in increased expression of PHGDH mRNA CTD PMID:24136188 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 decreases expression EXP nefazodone results in decreased expression of PHLDB2 mRNA CTD PMID:24136188 NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734 		JBrowse link
G Phtf1 putative homeodomain transcription factor 1 decreases expression EXP nefazodone results in decreased expression of PHTF1 mRNA CTD PMID:24136188 NCBI chr 2:194,161,343...194,249,925
Ensembl chr 2:194,161,000...194,219,530 		JBrowse link
G Pi4k2b phosphatidylinositol 4-kinase type 2 beta increases expression EXP nefazodone results in increased expression of PI4K2B mRNA CTD PMID:24136188 NCBI chr14:62,434,589...62,461,507
Ensembl chr14:62,424,511...62,461,446 		JBrowse link
G Pi4ka phosphatidylinositol 4-kinase alpha increases expression EXP nefazodone results in increased expression of PI4KA mRNA CTD PMID:24136188 NCBI chr11:97,113,390...97,234,374
Ensembl chr11:97,113,245...97,228,315 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 increases expression ISO nefazodone results in increased expression of PID1 mRNA CTD PMID:32816093 NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070 		JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C increases expression EXP nefazodone results in increased expression of PIGC mRNA CTD PMID:24136188 NCBI chr13:76,876,894...76,879,420
Ensembl chr13:76,872,922...76,880,224 		JBrowse link
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K increases expression EXP nefazodone results in increased expression of PIGK mRNA CTD PMID:24136188 NCBI chr 2:244,289,928...244,375,394
Ensembl chr 2:244,250,621...244,376,030 		JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P decreases expression EXP nefazodone results in decreased expression of PIGP mRNA CTD PMID:24136188 NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082 		JBrowse link
G Pigx phosphatidylinositol glycan anchor biosynthesis, class X increases expression EXP nefazodone results in increased expression of PIGX mRNA CTD PMID:24136188 NCBI chr11:82,192,125...82,208,062
Ensembl chr11:82,192,092...82,208,061 		JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of PIK3C2B mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2B mRNA 		CTD PMID:32152650 NCBI chr13:47,046,866...47,107,733
Ensembl chr13:47,047,127...47,107,725 		JBrowse link
G Pik3c2g phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of PIK3C2G mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C2G mRNA 		CTD PMID:32152650 NCBI chr 4:174,215,527...174,583,378
Ensembl chr 4:174,215,527...174,581,705 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of PIK3C3 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3C3 mRNA 		CTD PMID:32152650 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of PIK3R1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of PIK3R1 mRNA 		CTD PMID:32152650 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347 		JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase increases expression EXP nefazodone results in increased expression of PIM3 mRNA CTD PMID:24136188 NCBI chr 7:121,822,076...121,836,257
Ensembl chr 7:121,832,742...121,836,259 		JBrowse link
G Pink1 PTEN induced kinase 1 increases expression EXP nefazodone results in increased expression of PINK1 mRNA CTD PMID:24136188 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:155,813,838...155,825,950 		JBrowse link
G Pir pirin increases expression EXP nefazodone results in increased expression of PIR mRNA CTD PMID:24136188 NCBI chr  X:33,740,428...33,851,049
Ensembl chr  X:33,740,429...33,851,049 		JBrowse link
G Pithd1 PITH domain containing 1 increases expression EXP nefazodone results in increased expression of PITHD1 mRNA CTD PMID:24136188 NCBI chr 5:153,489,529...153,500,025
Ensembl chr 5:153,489,529...153,500,261 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic decreases expression EXP nefazodone results in decreased expression of PKDCC mRNA CTD PMID:24136188 NCBI chr 6:17,208,171...17,217,488
Ensembl chr 6:17,208,171...17,218,042 		JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP nefazodone results in decreased expression of PKLR mRNA CTD PMID:24136188 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP nefazodone results in increased expression of PLA2G12A mRNA CTD PMID:24136188 NCBI chr 2:221,110,722...221,126,966
Ensembl chr 2:221,110,685...221,126,964 		JBrowse link
G Plaa phospholipase A2, activating protein increases expression EXP nefazodone results in increased expression of PLAA mRNA CTD PMID:24136188 NCBI chr 5:114,544,327...114,576,023
Ensembl chr 5:114,544,325...114,576,109 		JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 decreases expression EXP nefazodone results in decreased expression of PLAAT3 mRNA CTD PMID:24136188 NCBI chr 1:214,211,755...214,245,551
Ensembl chr 1:214,211,791...214,246,763 		JBrowse link
G Plbd1 phospholipase B domain containing 1 decreases expression EXP nefazodone results in decreased expression of PLBD1 mRNA CTD PMID:24136188 NCBI chr 4:171,204,198...171,260,488
Ensembl chr 4:171,204,198...171,260,488 		JBrowse link
G Plekhb1 pleckstrin homology domain containing B1 decreases expression EXP nefazodone results in decreased expression of PLEKHB1 mRNA CTD PMID:24136188 NCBI chr 1:164,410,901...164,425,216
Ensembl chr 1:164,410,903...164,428,568 		JBrowse link
G Plg plasminogen decreases expression EXP nefazodone results in decreased expression of PLG mRNA CTD PMID:24136188 NCBI chr 1:50,872,927...50,915,406
Ensembl chr 1:50,872,926...50,917,320 		JBrowse link
G Plod1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 increases expression EXP nefazodone results in increased expression of PLOD1 mRNA CTD PMID:24136188 NCBI chr 5:163,623,847...163,650,737
Ensembl chr 5:163,623,848...163,651,110 		JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression EXP nefazodone results in increased expression of PLPBP mRNA CTD PMID:24136188 NCBI chr16:71,705,064...71,717,726
Ensembl chr16:71,700,028...71,717,726 		JBrowse link
G Plpp2 phospholipid phosphatase 2 increases expression EXP nefazodone results in increased expression of PLPP2 mRNA CTD PMID:24136188 NCBI chr 7:10,826,534...10,834,628
Ensembl chr 7:10,826,549...10,834,627 		JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression EXP nefazodone results in decreased expression of PLPP3 mRNA CTD PMID:24136188 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667 		JBrowse link
G Pls3 plastin 3 increases expression EXP nefazodone results in increased expression of PLS3 mRNA CTD PMID:24136188 NCBI chr  X:116,401,247...116,495,898
Ensembl chr  X:116,401,293...116,495,893 		JBrowse link
G Plxna2 plexin A2 decreases expression EXP nefazodone results in decreased expression of PLXNA2 mRNA CTD PMID:24136188 NCBI chr13:108,683,155...108,888,336
Ensembl chr13:108,691,530...108,887,453 		JBrowse link
G Plxnb2 plexin B2 decreases expression EXP nefazodone results in decreased expression of PLXNB2 mRNA CTD PMID:24136188 NCBI chr 7:122,111,917...122,138,201
Ensembl chr 7:122,111,917...122,127,746 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO nefazodone results in increased expression of PMAIP1 mRNA CTD PMID:27288927 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression EXP nefazodone results in increased expression of PMPCA mRNA CTD PMID:24136188 NCBI chr 3:29,605,823...29,614,936
Ensembl chr 3:29,604,232...29,614,935 		JBrowse link
G Pmvk phosphomevalonate kinase decreases expression EXP nefazodone results in decreased expression of PMVK mRNA CTD PMID:24136188 NCBI chr 2:177,174,344...177,184,076
Ensembl chr 2:177,174,335...177,184,080 		JBrowse link
G Pnisr PNN interacting serine and arginine rich protein decreases expression EXP nefazodone results in decreased expression of PNISR mRNA CTD PMID:24136188 NCBI chr 5:40,190,214...40,219,619
Ensembl chr 5:40,192,735...40,219,611 		JBrowse link
G Pnn pinin, desmosome associated protein decreases expression EXP nefazodone results in decreased expression of PNN mRNA CTD PMID:24136188 NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933 		JBrowse link
G Pno1 partner of NOB1 homolog increases expression EXP nefazodone results in increased expression of PNO1 mRNA CTD PMID:24136188 NCBI chr14:95,811,335...95,819,903
Ensembl chr14:95,688,125...95,905,881 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression EXP nefazodone results in increased expression of PNPLA2 mRNA CTD PMID:24136188 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:205,982,258...205,987,359 		JBrowse link
G Pnpla7 patatin-like phospholipase domain containing 7 increases expression EXP nefazodone results in increased expression of PNPLA7 mRNA CTD PMID:24136188 NCBI chr 3:28,180,670...28,259,673
Ensembl chr 3:28,180,751...28,259,672 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 increases expression EXP nefazodone results in increased expression of PNPLA8 mRNA CTD PMID:24136188 NCBI chr 6:67,056,783...67,118,714
Ensembl chr 6:67,056,697...67,120,512 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 decreases expression EXP nefazodone results in decreased expression of PNRC1 mRNA CTD PMID:24136188 NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression EXP nefazodone results in increased expression of POLD4 mRNA CTD PMID:24136188 NCBI chr 1:210,956,110...210,957,863
Ensembl chr 1:210,956,099...210,957,860 		JBrowse link
G Poldip2 DNA polymerase delta interacting protein 2 increases expression EXP nefazodone results in increased expression of POLDIP2 mRNA CTD PMID:24136188 NCBI chr10:63,905,287...63,915,655
Ensembl chr10:63,904,691...63,915,655 		JBrowse link
G Pole4 DNA polymerase epsilon 4, accessory subunit increases expression EXP nefazodone results in increased expression of POLE4 mRNA CTD PMID:24136188 NCBI chr 4:116,723,040...116,728,873
Ensembl chr 4:116,716,719...116,728,851 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit increases expression EXP nefazodone results in increased expression of POLG2 mRNA CTD PMID:24136188 NCBI chr10:92,212,303...92,222,849
Ensembl chr10:92,212,304...92,222,726 		JBrowse link
G Polr1f RNA polymerase I subunit F increases expression EXP nefazodone results in increased expression of POLR1F mRNA CTD PMID:24136188 NCBI chr 6:55,780,706...55,797,935
Ensembl chr 6:55,780,706...55,797,935 		JBrowse link
G Polr3d RNA polymerase III subunit D increases expression EXP nefazodone results in increased expression of POLR3D mRNA CTD PMID:24136188 NCBI chr15:51,921,283...51,925,952
Ensembl chr15:51,921,283...51,925,691 		JBrowse link
G Pomp proteasome maturation protein increases expression EXP nefazodone results in increased expression of POMP mRNA CTD PMID:24136188 NCBI chr12:12,198,262...12,212,132
Ensembl chr12:12,198,263...12,210,880 		JBrowse link
G Pon3 paraoxonase 3 decreases expression EXP nefazodone results in decreased expression of PON3 mRNA CTD PMID:24136188 NCBI chr 4:34,323,546...34,350,244
Ensembl chr 4:34,315,889...34,350,244 		JBrowse link
G Pop5 POP5 homolog, ribonuclease P/MRP subunit increases expression EXP nefazodone results in increased expression of POP5 mRNA CTD PMID:24136188 NCBI chr12:47,037,451...47,045,778
Ensembl chr12:47,029,403...47,042,032 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP nefazodone results in increased expression of POR mRNA CTD PMID:24136188 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases expression EXP nefazodone results in increased expression of PPA1 mRNA CTD PMID:24136188 NCBI chr20:30,132,088...30,160,492
Ensembl chr20:30,133,504...30,160,489 		JBrowse link
G Ppa2 inorganic pyrophosphatase 2 decreases expression EXP nefazodone results in decreased expression of PPA2 mRNA CTD PMID:24136188 NCBI chr 2:224,472,738...224,552,101
Ensembl chr 2:224,474,823...224,552,628 		JBrowse link
G Ppan peter pan homolog increases expression EXP nefazodone results in increased expression of PPAN mRNA CTD PMID:24136188 NCBI chr 8:27,700,147...27,704,127
Ensembl chr 8:27,700,152...27,704,128 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PPARA mRNA CTD PMID:33819548 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase increases expression EXP nefazodone results in increased expression of PPAT mRNA CTD PMID:24136188 NCBI chr14:31,570,010...31,604,410
Ensembl chr14:31,551,388...31,604,405 		JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP nefazodone results in increased expression of PPCS mRNA CTD PMID:24136188 NCBI chr 5:138,308,394...138,312,047
Ensembl chr 5:138,308,397...138,312,012 		JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor decreases expression EXP nefazodone results in decreased expression of PPDPF mRNA CTD PMID:24136188 NCBI chr 3:188,676,821...188,678,599
Ensembl chr 3:188,676,965...188,678,599 		JBrowse link
G Ppfibp2 PPFIA binding protein 2 decreases expression EXP nefazodone results in decreased expression of PPFIBP2 mRNA CTD PMID:24136188 NCBI chr 1:170,916,649...171,062,096
Ensembl chr 1:170,916,649...171,065,618 		JBrowse link
G Ppie peptidylprolyl isomerase E increases expression EXP nefazodone results in increased expression of PPIE mRNA CTD PMID:24136188 NCBI chr 5:140,691,285...140,704,347
Ensembl chr 5:140,683,801...140,740,767 		JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression EXP nefazodone results in increased expression of PPM1K mRNA CTD PMID:24136188 NCBI chr 4:88,942,226...88,969,139
Ensembl chr 4:88,942,386...88,969,136 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta increases expression EXP nefazodone results in increased expression of PPP1CB mRNA CTD PMID:24136188 NCBI chr 6:29,681,099...29,712,835
Ensembl chr 6:29,681,100...29,712,924 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B increases expression EXP nefazodone results in increased expression of PPP1R14B mRNA CTD PMID:24136188 NCBI chr 1:213,594,416...213,596,527
Ensembl chr12:21,088,517...21,101,431
Ensembl chr 1:21,088,517...21,101,431 		JBrowse link
G Ppp1r21 protein phosphatase 1, regulatory subunit 21 decreases expression EXP nefazodone results in decreased expression of PPP1R21 mRNA CTD PMID:24136188 NCBI chr 6:11,655,059...11,724,219
Ensembl chr 6:11,655,059...11,724,219 		JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP nefazodone results in decreased expression of PPP1R3B mRNA CTD PMID:24136188 NCBI chr16:63,533,318...63,545,683
Ensembl chr16:63,532,842...63,549,997 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of PPP1R3C mRNA CTD PMID:33819548 NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta increases expression EXP nefazodone results in increased expression of PPP2CB mRNA CTD PMID:24136188 NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP nefazodone results in increased expression of PPP2R1A mRNA CTD PMID:24136188 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242 		JBrowse link
G Ppp2r2d protein phosphatase 2, regulatory subunit B, delta increases expression EXP nefazodone results in increased expression of PPP2R2D mRNA CTD PMID:24136188 NCBI chr 1:203,095,536...203,129,895
Ensembl chr 1:203,095,531...203,129,893 		JBrowse link
G Ppp2r5a protein phosphatase 2, regulatory subunit B', alpha decreases expression EXP nefazodone results in decreased expression of PPP2R5A mRNA CTD PMID:24136188 NCBI chr13:105,462,371...105,506,767
Ensembl chr13:105,462,371...105,506,767 		JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon decreases expression EXP nefazodone results in decreased expression of PPP2R5E mRNA CTD PMID:24136188 NCBI chr 6:99,904,569...100,053,672
Ensembl chr 6:99,904,569...100,053,573 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta increases expression EXP nefazodone results in increased expression of PPP3CB mRNA CTD PMID:24136188 NCBI chr15:3,809,182...3,854,204
Ensembl chr15:3,809,262...3,854,203 		JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha increases expression EXP nefazodone results in increased expression of PPP3R1 mRNA CTD PMID:24136188 NCBI chr14:95,758,333...95,808,015 JBrowse link
G Ppp6c protein phosphatase 6, catalytic subunit increases expression EXP nefazodone results in increased expression of PPP6C mRNA CTD PMID:24136188 NCBI chr 3:43,339,521...43,371,807
Ensembl chr 3:43,341,108...43,371,807 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression EXP nefazodone results in increased expression of PRDX1 mRNA CTD PMID:24136188 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504 		JBrowse link
G Prdx3 peroxiredoxin 3 increases expression EXP nefazodone results in increased expression of PRDX3 mRNA CTD PMID:24136188 NCBI chr 1:269,987,691...270,000,111
Ensembl chr 1:269,987,685...270,000,300 		JBrowse link
G Prdx5 peroxiredoxin 5 increases expression EXP nefazodone results in increased expression of PRDX5 mRNA CTD PMID:24136188 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020 		JBrowse link
G Prdx6 peroxiredoxin 6 increases expression EXP nefazodone results in increased expression of PRDX6 mRNA CTD PMID:24136188 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:76,061,554...76,072,657 		JBrowse link
G Preb prolactin regulatory element binding increases expression EXP nefazodone results in increased expression of PREB mRNA CTD PMID:24136188 NCBI chr 6:31,138,757...31,142,544
Ensembl chr 6:31,138,743...31,142,540 		JBrowse link
G Prelid3b PRELI domain containing 3B increases expression EXP nefazodone results in increased expression of PRELID3B mRNA CTD PMID:24136188 NCBI chr 3:183,681,257...183,689,253
Ensembl chr 3:183,681,255...183,689,289 		JBrowse link
G Prkab1 protein kinase AMP-activated non-catalytic subunit beta 1 decreases expression EXP nefazodone results in decreased expression of PRKAB1 mRNA CTD PMID:24136188 NCBI chr12:46,248,971...46,259,487
Ensembl chr12:46,249,010...46,259,482 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases expression EXP nefazodone results in decreased expression of PRKACA mRNA CTD PMID:24136188 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha increases expression EXP nefazodone results in increased expression of PRKAR1A mRNA CTD PMID:24136188 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:95,120,487...95,139,025 		JBrowse link
G Prkci protein kinase C, iota increases expression EXP nefazodone results in increased expression of PRKCI mRNA CTD PMID:24136188 NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:114,250,398...114,310,784 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 increases expression EXP nefazodone results in increased expression of PRMT1 mRNA CTD PMID:24136188 NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:104,595,335...104,604,827 		JBrowse link
G Prodh1 proline dehydrogenase 1 decreases expression EXP nefazodone results in decreased expression of PRODH mRNA CTD PMID:24136188 NCBI chr11:96,414,275...96,431,604
Ensembl chr11:96,414,224...96,433,418 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 increases expression EXP nefazodone results in increased expression of PRPF19 mRNA CTD PMID:24136188 NCBI chr 1:216,966,104...216,977,549
Ensembl chr 1:216,966,462...216,980,506 		JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 increases expression EXP nefazodone results in increased expression of PRPS1 mRNA CTD PMID:24136188 NCBI chr  X:108,920,663...108,942,713
Ensembl chr  X:108,920,651...108,942,711 		JBrowse link
G Prss23 serine protease 23 decreases expression EXP nefazodone results in decreased expression of PRSS23 mRNA CTD PMID:24136188 NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871 		JBrowse link
G Prxl2b peroxiredoxin like 2B decreases expression EXP nefazodone results in decreased expression of PRXL2B mRNA CTD PMID:24136188 NCBI chr 5:170,744,953...170,747,556
Ensembl chr 5:170,744,953...170,747,556 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression EXP nefazodone results in increased expression of PSAT1 mRNA CTD PMID:24136188 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693 		JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP nefazodone results in increased expression of PSMA1 mRNA CTD PMID:24136188 NCBI chr 1:177,876,838...177,887,857
Ensembl chr 1:177,875,353...177,887,949 		JBrowse link
G Psma2 proteasome 20S subunit alpha 2 increases expression EXP nefazodone results in increased expression of PSMA2 mRNA CTD PMID:24136188 NCBI chr17:55,250,054...55,260,441
Ensembl chr17:55,247,442...55,339,673 		JBrowse link
G Psma3 proteasome 20S subunit alpha 3 increases expression EXP nefazodone results in increased expression of PSMA3 mRNA CTD PMID:24136188 NCBI chr 6:95,219,714...95,239,745
Ensembl chr 6:95,219,629...95,241,032 		JBrowse link
G Psma4 proteasome 20S subunit alpha 4 increases expression EXP nefazodone results in increased expression of PSMA4 mRNA CTD PMID:24136188 NCBI chr 8:64,236,520...64,243,980
Ensembl chr 8:64,236,783...64,243,979 		JBrowse link
G Psma5 proteasome 20S subunit alpha 5 increases expression EXP nefazodone results in increased expression of PSMA5 mRNA CTD PMID:24136188 NCBI chr 2:198,584,502...198,607,867
Ensembl chr 2:198,584,505...198,607,867 		JBrowse link
G Psma6 proteasome 20S subunit alpha 6 increases expression EXP nefazodone results in increased expression of PSMA6 mRNA CTD PMID:24136188 NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717 		JBrowse link
G Psma7 proteasome 20S subunit alpha 7 increases expression EXP nefazodone results in increased expression of PSMA7 mRNA CTD PMID:24136188 NCBI chr 3:187,514,901...187,521,289
Ensembl chr 3:187,513,441...187,521,253 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 increases expression EXP nefazodone results in increased expression of PSMB1 mRNA CTD PMID:24136188 NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640 		JBrowse link
G Psmb2 proteasome 20S subunit beta 2 increases expression EXP nefazodone results in increased expression of PSMB2 mRNA CTD PMID:24136188 NCBI chr 5:144,255,058...144,287,200
Ensembl chr 5:144,255,026...144,287,608 		JBrowse link
G Psmb3 proteasome 20S subunit beta 3 increases expression EXP nefazodone results in increased expression of PSMB3 mRNA CTD PMID:24136188 NCBI chr10:83,193,787...83,200,883
Ensembl chr10:83,193,787...83,200,883 		JBrowse link
G Psmb4 proteasome 20S subunit beta 4 increases expression EXP nefazodone results in increased expression of PSMB4 mRNA CTD PMID:24136188 NCBI chr 2:185,131,787...185,134,561
Ensembl chr 2:185,131,786...185,135,287 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 increases expression EXP nefazodone results in increased expression of PSMB5 mRNA CTD PMID:24136188 NCBI chr15:32,042,784...32,047,379
Ensembl chr15:32,042,787...32,047,379 		JBrowse link
G Psmb6 proteasome 20S subunit beta 6 increases expression EXP nefazodone results in increased expression of PSMB6 mRNA CTD PMID:24136188 NCBI chr10:55,737,852...55,740,218
Ensembl chr10:55,737,888...55,740,218 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 increases expression EXP nefazodone results in increased expression of PSMB7 mRNA CTD PMID:24136188 NCBI chr 3:42,767,500...42,827,470
Ensembl chr 3:42,767,501...42,827,601 		JBrowse link
G Psmb8 proteasome 20S subunit beta 8 decreases expression EXP nefazodone results in decreased expression of PSMB8 mRNA CTD PMID:24136188 NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression EXP nefazodone results in decreased expression of PSMB9 mRNA CTD PMID:24136188 NCBI chr20:4,668,952...4,674,421
Ensembl chr20:4,668,739...4,674,421 		JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 increases expression EXP nefazodone results in increased expression of PSMC1 mRNA CTD PMID:24136188 NCBI chr 6:125,122,497...125,134,859
Ensembl chr 6:125,122,490...125,134,858 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 increases expression EXP nefazodone results in increased expression of PSMC2 mRNA CTD PMID:24136188 NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:14,148,090...14,162,390 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression EXP nefazodone results in increased expression of PSMC3 mRNA CTD PMID:24136188 NCBI chr 3:97,487,643...97,493,025
Ensembl chr 3:97,487,632...97,499,176 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 increases expression EXP nefazodone results in increased expression of PSMC4 mRNA CTD PMID:24136188 NCBI chr 1:92,476,690...92,485,268
Ensembl chr 1:92,476,690...92,485,060 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression EXP nefazodone results in increased expression of PSMC5 mRNA CTD PMID:24136188 NCBI chr10:91,687,553...91,693,487
Ensembl chr10:91,686,295...91,695,921 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression EXP nefazodone results in increased expression of PSMC6 mRNA CTD PMID:24136188 NCBI chr15:21,022,314...21,043,785
Ensembl chr15:21,022,314...21,043,785 		JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 increases expression EXP nefazodone results in increased expression of PSMD1 mRNA CTD PMID:24136188 NCBI chr 9:94,157,971...94,233,218
Ensembl chr 9:94,157,971...94,233,218 		JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 increases expression EXP nefazodone results in increased expression of PSMD11 mRNA CTD PMID:24136188 NCBI chr10:65,923,669...65,977,523
Ensembl chr10:65,931,279...65,976,234 		JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression EXP nefazodone results in increased expression of PSMD12 mRNA CTD PMID:24136188 NCBI chr10:92,937,957...92,956,601
Ensembl chr10:92,901,133...92,988,964 		JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 increases expression EXP nefazodone results in increased expression of PSMD13 mRNA CTD PMID:24136188 NCBI chr 1:205,394,248...205,406,525
Ensembl chr 1:205,393,746...205,411,651 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 increases expression EXP nefazodone results in increased expression of PSMD14 mRNA CTD PMID:24136188 NCBI chr 3:66,662,933...66,755,666
Ensembl chr 3:66,662,900...66,755,665 		JBrowse link
G Psmd2 proteasome 26S subunit ubiquitin receptor, non-ATPase 2 increases expression EXP nefazodone results in increased expression of PSMD2 mRNA CTD PMID:24136188 NCBI chr11:93,752,761...93,763,388
Ensembl chr11:93,752,763...93,763,388 		JBrowse link
G Psmd3 proteasome 26S subunit, non-ATPase 3 increases expression EXP nefazodone results in increased expression of PSMD3 mRNA CTD PMID:24136188 NCBI chr10:84,139,249...84,151,879
Ensembl chr10:84,139,677...84,151,878 		JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 increases expression EXP nefazodone results in increased expression of PSMD4 mRNA CTD PMID:24136188 NCBI chr 2:185,287,941...185,297,238
Ensembl chr 2:185,286,868...185,297,201 		JBrowse link
G Psmd5 proteasome 26S subunit, non-ATPase 5 increases expression EXP nefazodone results in increased expression of PSMD5 mRNA CTD PMID:24136188 NCBI chr 3:38,531,206...38,552,085
Ensembl chr 3:38,530,951...38,548,490 		JBrowse link
G Psmd6 proteasome 26S subunit, non-ATPase 6 increases expression EXP nefazodone results in increased expression of PSMD6 mRNA CTD PMID:24136188 NCBI chr15:13,532,675...13,542,682
Ensembl chr15:13,532,675...13,542,682 		JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression EXP nefazodone results in increased expression of PSMD7 mRNA CTD PMID:24136188 NCBI chr19:52,404,032...52,411,316
Ensembl chr19:52,404,032...52,417,871 		JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 increases expression EXP nefazodone results in increased expression of PSMD8 mRNA CTD PMID:24136188 NCBI chr 1:93,601,857...93,608,689
Ensembl chr 1:93,601,853...93,608,689 		JBrowse link
G Psmd9 proteasome 26S subunit, non-ATPase 9 increases expression EXP nefazodone results in increased expression of PSMD9 mRNA CTD PMID:24136188 NCBI chr12:38,998,027...39,018,340
Ensembl chr12:38,998,030...39,018,679 		JBrowse link
G Psme3 proteasome activator subunit 3 increases expression EXP nefazodone results in increased expression of PSME3 mRNA CTD PMID:24136188 NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,757,899...86,818,033 		JBrowse link
G Psme4 proteasome activator subunit 4 increases expression EXP nefazodone results in increased expression of PSME4 mRNA CTD PMID:24136188 NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328 		JBrowse link
G Psmg2 proteasome assembly chaperone 2 increases expression EXP nefazodone results in increased expression of PSMG2 mRNA CTD PMID:24136188 NCBI chr18:63,478,620...63,493,193 JBrowse link
G Psmg3 proteasome assembly chaperone 3 increases expression EXP nefazodone results in increased expression of PSMG3 mRNA CTD PMID:24136188 NCBI chr12:19,923,288...19,926,205
Ensembl chr12:19,923,288...19,926,205 		JBrowse link
G Pten phosphatase and tensin homolog increases expression EXP nefazodone results in increased expression of PTEN mRNA CTD PMID:24136188 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330 		JBrowse link
G Ptges3l1 prostaglandin E synthase 3-like 1 increases expression EXP nefazodone results in increased expression of PTGES3L1 mRNA CTD PMID:24136188 NCBI chr  X:46,092,665...46,101,937
Ensembl chr  X:46,092,206...46,107,019 		JBrowse link
G Ptgr3 prostaglandin reductase 3 increases expression EXP nefazodone results in increased expression of PTGR3 mRNA CTD PMID:24136188 NCBI chr18:79,729,282...79,738,632
Ensembl chr18:79,729,282...79,738,632 		JBrowse link
G Ptms parathymosin decreases expression EXP nefazodone results in decreased expression of PTMS mRNA CTD PMID:24136188 NCBI chr 4:159,408,647...159,412,837
Ensembl chr 4:159,408,649...159,415,212 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 increases expression EXP nefazodone results in increased expression of PTPMT1 mRNA CTD PMID:24136188 NCBI chr 3:97,345,752...97,355,396
Ensembl chr 3:97,345,752...97,355,254 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 increases expression EXP nefazodone results in increased expression of PTPN11 mRNA CTD PMID:24136188 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:41,043,785...41,085,577 		JBrowse link
G Ptpn21 protein tyrosine phosphatase, non-receptor type 21 increases expression EXP nefazodone results in increased expression of PTPN21 mRNA CTD PMID:24136188 NCBI chr 6:123,662,783...123,727,809
Ensembl chr 6:123,662,783...123,727,809 		JBrowse link
G Ptprb protein tyrosine phosphatase, receptor type, B decreases expression EXP nefazodone results in decreased expression of PTPRB mRNA CTD PMID:24136188 NCBI chr 7:53,816,197...53,920,760
Ensembl chr 7:53,816,097...53,920,760 		JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression EXP nefazodone results in decreased expression of PTPRD mRNA CTD PMID:24136188 NCBI chr 5:95,093,221...97,415,498
Ensembl chr 5:95,095,858...96,178,903 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression EXP nefazodone results in decreased expression of PTPRF mRNA CTD PMID:24136188 NCBI chr 5:137,027,376...137,109,405
Ensembl chr 5:137,028,164...137,095,426 		JBrowse link
G Pum3 pumilio RNA-binding family member 3 increases expression EXP nefazodone results in increased expression of PUM3 mRNA CTD PMID:24136188 NCBI chr 1:234,483,482...234,527,718
Ensembl chr 1:234,487,954...234,527,612 		JBrowse link
G Pum3l1 pumilio RNA-binding family member 3 like 1 increases expression EXP nefazodone results in increased expression of PUM3L1 mRNA CTD PMID:24136188 NCBI chr  X:154,615,637...154,617,736
Ensembl chr  X:154,615,648...154,617,733 		JBrowse link
G Pus1 pseudouridine synthase 1 increases expression EXP nefazodone results in increased expression of PUS1 mRNA CTD PMID:24136188 NCBI chr12:51,539,659...51,548,975
Ensembl chr12:51,540,212...51,548,973 		JBrowse link
G Pygl glycogen phosphorylase L decreases expression EXP nefazodone results in decreased expression of PYGL mRNA CTD PMID:24136188 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269 		JBrowse link
G R3hdm2 R3H domain containing 2 decreases expression EXP nefazodone results in decreased expression of R3HDM2 mRNA CTD PMID:24136188 NCBI chr 7:65,097,685...65,225,863
Ensembl chr 7:65,097,923...65,225,862 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family decreases expression EXP nefazodone results in decreased expression of RAB11B mRNA CTD PMID:24136188 NCBI chr 7:15,223,613...15,236,754
Ensembl chr 7:15,223,534...15,236,756 		JBrowse link
G Rab21 RAB21, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB21 mRNA CTD PMID:24136188 NCBI chr 7:52,790,158...52,814,943
Ensembl chr 7:52,790,165...52,814,943 		JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB28 mRNA CTD PMID:24136188 NCBI chr14:73,458,386...73,535,367
Ensembl chr14:73,458,249...73,535,369 		JBrowse link
G Rab2a RAB2A, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB2A mRNA CTD PMID:24136188 NCBI chr 5:26,473,424...26,537,441
Ensembl chr 5:26,473,548...26,538,488 		JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB30 mRNA CTD PMID:24136188 NCBI chr 1:156,216,137...156,310,778
Ensembl chr 1:156,216,137...156,310,778 		JBrowse link
G Rab34 RAB34, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB34 mRNA CTD PMID:24136188 NCBI chr10:63,581,542...63,585,608
Ensembl chr10:63,580,997...63,586,083 		JBrowse link
G Rab38 RAB38, member RAS oncogene family decreases expression EXP nefazodone results in decreased expression of RAB38 mRNA CTD PMID:24136188 NCBI chr 1:151,595,153...151,675,492
Ensembl chr 1:151,595,078...151,675,493 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB5A mRNA CTD PMID:24136188 NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447 		JBrowse link
G Rab5if RAB5 interacting factor increases expression EXP nefazodone results in increased expression of RAB5IF mRNA CTD PMID:24136188 NCBI chr 3:165,818,060...165,828,071
Ensembl chr 3:165,816,588...165,828,067 		JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAB6A mRNA CTD PMID:24136188 NCBI chr 1:164,370,033...164,422,324
Ensembl chr 1:164,369,861...164,417,763 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression EXP nefazodone results in decreased expression of RAB7A mRNA CTD PMID:24136188 NCBI chr 4:122,019,281...122,068,067
Ensembl chr 4:121,983,938...122,064,185 		JBrowse link
G Rack1 receptor for activated C kinase 1 increases expression EXP nefazodone results in increased expression of RACK1 mRNA CTD PMID:24136188 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,670,270...33,675,948 		JBrowse link
G Rad23b RAD23 homolog B, nucleotide excision repair protein increases expression EXP nefazodone results in increased expression of RAD23B mRNA CTD PMID:24136188 NCBI chr 5:74,885,518...74,923,621
Ensembl chr 5:74,885,516...74,962,426 		JBrowse link
G Rala RAS like proto-oncogene A increases expression
multiple interactions 		ISO nefazodone results in increased expression of RALA mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RALA mRNA 		CTD PMID:32152650 NCBI chr17:51,787,682...51,840,738
Ensembl chr17:51,787,699...51,840,733 		JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit increases expression EXP nefazodone results in increased expression of RAMAC mRNA CTD PMID:24136188 NCBI chr 1:145,117,752...145,123,640
Ensembl chr 1:145,117,736...145,124,256 		JBrowse link
G Ran RAN, member RAS oncogene family increases expression EXP nefazodone results in increased expression of RAN mRNA CTD PMID:24136188 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317 		JBrowse link
G Ranbp2 RAN binding protein 2 increases expression EXP nefazodone results in increased expression of RANBP2 mRNA CTD PMID:24136188 NCBI chr20:26,984,520...27,036,573
Ensembl chr20:26,985,275...27,036,571 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 increases expression EXP nefazodone results in increased expression of RANGAP1 mRNA CTD PMID:24136188 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:115,104,823...115,130,564 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions
decreases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of RAP1A mRNA
nefazodone results in decreased expression of RAP1A mRNA 		CTD PMID:32152650 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808 		JBrowse link
G Rarb retinoic acid receptor, beta decreases expression EXP nefazodone results in decreased expression of RARB mRNA CTD PMID:24136188 NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040 		JBrowse link
G Rarres1 retinoic acid receptor responder 1 decreases expression EXP nefazodone results in decreased expression of RARRES1 mRNA CTD PMID:24136188 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024 		JBrowse link
G Rarres2 retinoic acid receptor responder 2 decreases expression EXP nefazodone results in decreased expression of RARRES2 mRNA CTD PMID:24136188 NCBI chr 4:78,853,450...78,856,652
Ensembl chr 4:78,853,453...78,856,457 		JBrowse link
G Rars1 arginyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of RARS1 mRNA CTD PMID:24136188 NCBI chr10:20,774,804...20,799,251
Ensembl chr10:20,774,805...20,799,251 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP nefazodone results in decreased expression of RB1 mRNA CTD PMID:24136188 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857 		JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor increases expression EXP nefazodone results in increased expression of RBBP7 mRNA CTD PMID:24136188 NCBI chr  X:35,544,873...35,563,030
Ensembl chr  X:35,544,873...35,563,030 		JBrowse link
G Rbfa ribosome binding factor A decreases expression EXP nefazodone results in decreased expression of RBFA mRNA CTD PMID:24136188 NCBI chr18:75,914,247...75,923,893
Ensembl chr18:75,914,145...75,939,219 		JBrowse link
G Rbis ribosomal biogenesis factor increases expression EXP nefazodone results in increased expression of RBIS mRNA CTD PMID:24136188 NCBI chr 2:88,702,599...88,718,587
Ensembl chr 2:88,702,536...88,719,527 		JBrowse link
G Rbm26 RNA binding motif protein 26 decreases expression EXP nefazodone results in decreased expression of RBM26 mRNA CTD PMID:24136188 NCBI chr15:88,299,378...88,379,365
Ensembl chr15:88,301,436...88,378,686 		JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP nefazodone results in increased expression of RBM3 mRNA CTD PMID:24136188 NCBI chr  X:17,020,863...17,024,341
Ensembl chr  X:17,020,864...17,024,841 		JBrowse link
G Rbm39 RNA binding motif protein 39 decreases expression EXP nefazodone results in decreased expression of RBM39 mRNA CTD PMID:24136188 NCBI chr 3:165,123,087...165,156,453
Ensembl chr 3:165,123,095...165,149,397 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression EXP nefazodone results in increased expression of RBPMS mRNA CTD PMID:24136188 NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503 		JBrowse link
G Rbx1 ring-box 1 increases expression EXP nefazodone results in increased expression of RBX1 mRNA CTD PMID:24136188 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:114,870,972...114,881,191 		JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP nefazodone results in decreased expression of RCAN1 mRNA CTD PMID:24136188 NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236 		JBrowse link
G Rcan2 regulator of calcineurin 2 increases expression EXP nefazodone results in increased expression of RCAN2 mRNA CTD PMID:24136188 NCBI chr 9:24,456,861...24,674,234
Ensembl chr 9:24,456,861...24,672,189 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 increases expression EXP nefazodone results in increased expression of RCC2 mRNA CTD PMID:24136188 NCBI chr 5:158,277,476...158,300,294
Ensembl chr 5:158,277,476...158,300,294 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 increases expression EXP nefazodone results in increased expression of RCHY1 mRNA CTD PMID:24136188 NCBI chr14:16,397,533...16,413,286
Ensembl chr14:16,397,494...16,413,451 		JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression EXP nefazodone results in decreased expression of RDH11 mRNA CTD PMID:24136188 NCBI chr 6:103,712,373...103,728,247
Ensembl chr 6:103,712,374...103,729,741 		JBrowse link
G Rdh16 retinol dehydrogenase 16 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of RDH16 mRNA CTD PMID:33819548 NCBI chr 7:65,499,763...65,510,304 JBrowse link
G Reep5 receptor accessory protein 5 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of REEP5 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of REEP5 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr18:26,219,528...26,257,505
Ensembl chr18:26,219,530...26,250,660 		JBrowse link
G Reep6 receptor accessory protein 6 increases expression EXP nefazodone results in increased expression of REEP6 mRNA CTD PMID:24136188 NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740 		JBrowse link
G Reln reelin decreases expression EXP nefazodone results in decreased expression of RELN mRNA CTD PMID:24136188 NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:13,628,399...14,055,162 		JBrowse link
G Retreg1 reticulophagy regulator 1 increases expression EXP nefazodone results in increased expression of RETREG1 mRNA CTD PMID:24136188 NCBI chr 2:78,045,435...78,205,316
Ensembl chr 2:78,066,031...78,225,356 		JBrowse link
G Rex1bd required for excision 1-B domain containing increases expression EXP nefazodone results in increased expression of REX1BD mRNA CTD PMID:24136188 NCBI chr16:18,956,023...18,958,494
Ensembl chr16:18,955,969...18,958,494 		JBrowse link
G Rexo2 RNA exonuclease 2 increases expression EXP nefazodone results in increased expression of REXO2 mRNA CTD PMID:24136188 NCBI chr 8:57,708,420...57,720,142
Ensembl chr 8:57,707,558...57,720,142 		JBrowse link
G Rfk riboflavin kinase increases expression EXP nefazodone results in increased expression of RFK mRNA CTD PMID:24136188 NCBI chr 1:224,226,632...224,234,185
Ensembl chr 1:224,226,628...224,235,698
Ensembl chr  X:224,226,628...224,235,698 		JBrowse link
G Rfk-ps3 riboflavin kinase, pseudogene 3 increases expression EXP nefazodone results in increased expression of RFK-PS3 mRNA CTD PMID:24136188 NCBI chr 3:106,965,232...106,967,412
Ensembl chr 3:106,954,321...106,967,418 		JBrowse link
G Rgn regucalcin decreases expression EXP nefazodone results in decreased expression of RGN mRNA CTD PMID:24136188 NCBI chr  X:4,172,537...4,190,112
Ensembl chr  X:4,172,537...4,190,251 		JBrowse link
G Rhbdd2 rhomboid domain containing 2 increases expression EXP nefazodone results in increased expression of RHBDD2 mRNA CTD PMID:24136188 NCBI chr12:26,680,206...26,690,926
Ensembl chr12:26,680,969...26,691,080 		JBrowse link
G Rheb Ras homolog, mTORC1 binding increases expression EXP nefazodone results in increased expression of RHEB mRNA CTD PMID:24136188 NCBI chr 4:11,012,173...11,053,860
Ensembl chr 4:11,012,643...11,053,931 		JBrowse link
G Rhob ras homolog family member B decreases expression EXP nefazodone results in decreased expression of RHOB mRNA CTD PMID:24136188 NCBI chr 6:37,083,030...37,085,204
Ensembl chr 6:37,075,015...37,112,772 		JBrowse link
G Rida reactive intermediate imine deaminase A homolog decreases expression EXP nefazodone results in decreased expression of RIDA mRNA CTD PMID:24136188 NCBI chr 7:67,576,586...67,590,493
Ensembl chr 7:67,576,586...67,590,692 		JBrowse link
G Rig1 RNA sensor RIG-1 decreases expression EXP nefazodone results in decreased expression of RIGI mRNA CTD PMID:24136188 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995 		JBrowse link
G Riok3 RIO kinase 3 increases expression EXP nefazodone results in increased expression of RIOK3 mRNA CTD PMID:24136188 NCBI chr18:3,602,535...3,628,108
Ensembl chr18:3,602,535...3,628,108 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression
multiple interactions 		ISO nefazodone results in increased expression of RIPK1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RIPK1 mRNA 		CTD PMID:32152650 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167 		JBrowse link
G Rmdn2 regulator of microtubule dynamics 2 decreases expression EXP nefazodone results in decreased expression of RMDN2 mRNA CTD PMID:24136188 NCBI chr 6:21,101,383...21,195,221
Ensembl chr 6:21,119,396...21,193,684 		JBrowse link
G Rmi1 RecQ mediated genome instability 1 decreases expression EXP nefazodone results in decreased expression of RMI1 mRNA CTD PMID:24136188 NCBI chr17:6,261,961...6,269,947
Ensembl chr17:6,260,896...6,282,052 		JBrowse link
G Rnase4 ribonuclease A family member 4 decreases expression EXP nefazodone results in decreased expression of RNASE4 mRNA CTD PMID:24136188 NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639 		JBrowse link
G Rnf10 ring finger protein 10 increases expression EXP nefazodone results in increased expression of RNF10 mRNA CTD PMID:24136188 NCBI chr12:47,002,409...47,036,201
Ensembl chr12:47,002,409...47,036,201 		JBrowse link
G Rnf113a2 ring finger protein 113A2 increases expression EXP nefazodone results in increased expression of RNF113A2 mRNA CTD PMID:24136188 NCBI chr 6:109,794,794...109,796,075
Ensembl chr 6:109,794,684...109,796,273 		JBrowse link
G Rnf114 ring finger protein 114 increases expression EXP nefazodone results in increased expression of RNF114 mRNA CTD PMID:24136188 NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960 		JBrowse link
G Rnf115 ring finger protein 115 increases expression EXP nefazodone results in increased expression of RNF115 mRNA CTD PMID:24136188 NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:186,950,760...187,019,561 		JBrowse link
G Rnf125 ring finger protein 125 decreases expression EXP nefazodone results in decreased expression of RNF125 mRNA CTD PMID:24136188 NCBI chr18:12,528,995...12,550,646
Ensembl chr18:12,528,838...12,554,430 		JBrowse link
G Rnf139 ring finger protein 139 increases expression EXP nefazodone results in increased expression of RNF139 mRNA CTD PMID:24136188 NCBI chr 7:92,329,201...92,340,386
Ensembl chr 7:92,329,157...92,341,721 		JBrowse link
G Rnf14 ring finger protein 14 increases expression EXP nefazodone results in increased expression of RNF14 mRNA CTD PMID:24136188 NCBI chr18:30,381,072...30,406,859
Ensembl chr18:30,382,857...30,406,774 		JBrowse link
G Rnf149 ring finger protein 149 increases expression EXP nefazodone results in increased expression of RNF149 mRNA CTD PMID:24136188 NCBI chr 9:49,322,524...49,350,361
Ensembl chr 9:49,323,857...49,350,042 		JBrowse link
G Rnf187 ring finger protein 187 increases expression EXP nefazodone results in increased expression of RNF187 mRNA CTD PMID:24136188 NCBI chr10:44,209,080...44,214,979
Ensembl chr10:44,202,332...44,215,470 		JBrowse link
G Rnf39 ring finger protein 39 decreases expression EXP nefazodone results in decreased expression of RNF39 mRNA CTD PMID:24136188 NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323 		JBrowse link
G Rnf4 ring finger protein 4 increases expression EXP nefazodone results in increased expression of RNF4 mRNA CTD PMID:24136188 NCBI chr14:80,625,864...80,647,138
Ensembl chr14:80,625,866...80,647,148 		JBrowse link
G Rnf7 ring finger protein 7 increases expression EXP nefazodone results in increased expression of RNF7 mRNA CTD PMID:24136188 NCBI chr 8:105,918,395...105,927,643
Ensembl chr 8:105,918,395...105,927,405 		JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 increases expression EXP nefazodone results in increased expression of RNH1 mRNA CTD PMID:24136188 NCBI chr 1:205,698,882...205,711,348
Ensembl chr 1:205,698,882...205,711,582 		JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 increases expression EXP nefazodone results in increased expression of RNPS1 mRNA CTD PMID:24136188 NCBI chr10:13,950,151...13,960,396
Ensembl chr10:13,950,184...13,960,393 		JBrowse link
G Rogdi rogdi atypical leucine zipper increases expression EXP nefazodone results in increased expression of ROGDI mRNA CTD PMID:24136188 NCBI chr10:11,074,288...11,078,907
Ensembl chr10:11,074,262...11,078,906 		JBrowse link
G Rora RAR-related orphan receptor A decreases expression EXP nefazodone results in decreased expression of RORA mRNA CTD PMID:24136188 NCBI chr 8:78,182,710...78,915,730
Ensembl chr 8:78,182,620...78,915,730 		JBrowse link
G Rorc RAR-related orphan receptor C decreases expression EXP nefazodone results in decreased expression of RORC mRNA CTD PMID:24136188 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566 		JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase decreases expression EXP nefazodone results in decreased expression of H4C8 mRNA CTD PMID:24136188 NCBI chr20:31,975,328...32,126,675
Ensembl chr20:31,975,329...32,126,547 		JBrowse link
G Rpa1 replication protein A1 decreases expression EXP nefazodone results in decreased expression of RPA1 mRNA CTD PMID:24136188 NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279 		JBrowse link
G Rpl10a ribosomal protein L10A increases expression EXP nefazodone results in increased expression of RPL10A mRNA CTD PMID:24136188 NCBI chr20:6,390,533...6,393,091
Ensembl chr20:6,390,179...6,393,091 		JBrowse link
G Rpl12a-ps1 ribosomal protein L12, pseudogene 1 increases expression EXP nefazodone results in increased expression of RPL12A-PS1 mRNA CTD PMID:24136188 NCBI chr 7:54,252,702...54,253,424 JBrowse link
G Rpl15 ribosomal protein L15 increases expression EXP nefazodone results in increased expression of RPL15 mRNA CTD PMID:24136188 NCBI chr15:9,934,663...9,937,946
Ensembl chr15:9,934,679...9,938,308 		JBrowse link
G Rpl17 ribosomal protein L17 increases expression EXP nefazodone results in increased expression of RPL17 mRNA CTD PMID:24136188 NCBI chr18:70,856,275...70,859,388
Ensembl chr 3:111,722,010...111,722,638
Ensembl chr18:111,722,010...111,722,638 		JBrowse link
G Rpl18 ribosomal protein L18 increases expression EXP nefazodone results in increased expression of RPL18 mRNA CTD PMID:24136188 NCBI chr 1:105,325,269...105,327,911
Ensembl chr 1:105,325,250...105,327,910 		JBrowse link
G Rpl18a ribosomal protein L18A increases expression EXP nefazodone results in increased expression of RPL18A mRNA CTD PMID:24136188 NCBI chr16:18,576,467...18,578,653
Ensembl chr 1:70,166,729...70,167,654
Ensembl chr16:70,166,729...70,167,654 		JBrowse link
G Rpl22l1 ribosomal protein L22 like 1 increases expression EXP nefazodone results in increased expression of RPL22L1 mRNA CTD PMID:24136188 NCBI chr 2:113,683,196...113,685,132
Ensembl chr 2:113,683,196...113,685,132 		JBrowse link
G Rpl23 ribosomal protein L23 increases expression EXP nefazodone results in increased expression of RPL23 mRNA CTD PMID:24136188 NCBI chr10:83,268,223...83,272,184
Ensembl chr10:83,262,592...83,272,214 		JBrowse link
G Rpl3 ribosomal protein L3 increases expression EXP nefazodone results in increased expression of RPL3 mRNA CTD PMID:24136188 NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990 		JBrowse link
G Rpl36a ribosomal protein L36A increases expression EXP nefazodone results in increased expression of RPL36A mRNA CTD PMID:24136188 NCBI chr  X:102,058,573...102,062,162
Ensembl chr20:22,034,086...22,034,406 		JBrowse link
G Rpl7l1 ribosomal protein L7-like 1 increases expression EXP nefazodone results in increased expression of RPL7L1 mRNA CTD PMID:24136188 NCBI chr 9:21,695,718...21,703,736
Ensembl chr 9:21,695,707...21,703,735 		JBrowse link
G Rpl8 ribosomal protein L8 increases expression EXP nefazodone results in increased expression of RPL8 mRNA CTD PMID:24136188 NCBI chr 7:110,506,815...110,509,106
Ensembl chr 7:110,506,800...110,509,103
Ensembl chr 3:110,506,800...110,509,103 		JBrowse link
G Rpl9 ribosomal protein L9 increases expression EXP nefazodone results in increased expression of RPL9 mRNA CTD PMID:24136188 NCBI chr14:43,247,536...43,250,784
Ensembl chr14:43,247,588...43,250,782
Ensembl chr 1:43,247,588...43,250,782 		JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression EXP nefazodone results in increased expression of RPLP2 mRNA CTD PMID:24136188 NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 decreases expression EXP nefazodone results in decreased expression of RPP21 mRNA CTD PMID:24136188 NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,023,186...2,025,308 		JBrowse link
G Rps12 ribosomal protein S12 increases expression EXP nefazodone results in increased expression of RPS12 mRNA CTD PMID:24136188 NCBI chr 1:23,499,943...23,502,234
Ensembl chr 1:23,500,073...23,502,235 		JBrowse link
G Rps14 ribosomal protein S14 increases expression EXP nefazodone results in increased expression of RPS14 mRNA CTD PMID:24136188 NCBI chr18:56,492,010...56,503,092
Ensembl chr18:56,498,245...56,503,091 		JBrowse link
G Rps15 ribosomal protein S15 increases expression EXP nefazodone results in increased expression of RPS15 mRNA CTD PMID:24136188 NCBI chr 7:10,066,572...10,068,167
Ensembl chr 7:10,066,677...10,068,123 		JBrowse link
G Rps16 ribosomal protein S16 increases expression EXP nefazodone results in increased expression of RPS16 mRNA CTD PMID:24136188 NCBI chr 1:92,770,658...92,773,603
Ensembl chr19:56,922,246...56,923,020
Ensembl chr 1:56,922,246...56,923,020 		JBrowse link
G Rps17 ribosomal protein S17 increases expression EXP nefazodone results in increased expression of RPS17 mRNA CTD PMID:24136188 NCBI chr 1:144,705,150...144,707,736
Ensembl chr 1:144,705,149...144,707,734
Ensembl chr 8:144,705,149...144,707,734 		JBrowse link
G Rps2 ribosomal protein S2 increases expression EXP nefazodone results in increased expression of RPS2 mRNA CTD PMID:24136188 NCBI chr10:14,251,841...14,253,697
Ensembl chr10:14,251,380...14,253,695 		JBrowse link
G Rps2-ps38 ribosomal protein S2, pseudogene 38 increases expression EXP nefazodone results in increased expression of RPS2-PS38 mRNA CTD PMID:24136188 NCBI chr11:51,891,059...51,891,931 JBrowse link
G Rps20 ribosomal protein S20 increases expression EXP nefazodone results in increased expression of RPS20 mRNA CTD PMID:24136188 NCBI chr 5:21,616,687...21,618,068
Ensembl chr 3:42,839,965...43,095,621
Ensembl chr 9:42,839,965...43,095,621
Ensembl chr 5:42,839,965...43,095,621 		JBrowse link
G Rps21-ps1 ribosomal protein S21, pseudogene 1 increases expression EXP nefazodone results in increased expression of RPS21 mRNA CTD PMID:24136188 NCBI chr 5:158,670,141...158,670,484
Ensembl chr 5:158,670,116...158,670,490 		JBrowse link
G Rps27a ribosomal protein S27a increases expression EXP nefazodone results in increased expression of RPS27A mRNA CTD PMID:24136188 NCBI chr14:107,486,664...107,488,941
Ensembl chr 5:138,465,088...138,466,080
Ensembl chr14:138,465,088...138,466,080
Ensembl chr 5:138,465,088...138,466,080 		JBrowse link
G Rps3 ribosomal protein S3 increases expression EXP nefazodone results in increased expression of RPS3 mRNA CTD PMID:24136188 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:163,189,842...163,195,776 		JBrowse link
G Rps5 ribosomal protein S5 increases expression EXP nefazodone results in increased expression of RPS5 mRNA CTD PMID:24136188 NCBI chr 1:82,610,965...82,615,262
Ensembl chr 1:82,610,965...82,615,262 		JBrowse link
G Rps6 ribosomal protein S6 increases expression EXP nefazodone results in increased expression of RPS6 mRNA CTD PMID:24136188 NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566 		JBrowse link
G Rps9 ribosomal protein S9 increases expression EXP nefazodone results in increased expression of RPS9 mRNA CTD PMID:24136188 NCBI chr 1:74,427,084...74,430,513
Ensembl chr 1:74,427,087...74,430,105 		JBrowse link
G Rpsa ribosomal protein SA increases expression EXP nefazodone results in increased expression of RPSA mRNA CTD PMID:24136188 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737 		JBrowse link
G Rragc Ras-related GTP binding C increases expression EXP nefazodone results in increased expression of RRAGC mRNA CTD PMID:24136188 NCBI chr 5:141,433,014...141,452,546
Ensembl chr 5:141,433,040...141,452,548 		JBrowse link
G Rras2 RAS related 2 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of RRAS2 mRNA CTD PMID:32152650 NCBI chr 1:177,668,143...177,737,551
Ensembl chr 1:177,668,144...177,737,551 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP nefazodone results in decreased expression of RRM2 mRNA CTD PMID:24136188 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor increases expression EXP nefazodone results in increased expression of RRN3 mRNA CTD PMID:24136188 NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330 		JBrowse link
G Rsrc2 arginine and serine rich coiled-coil 2 decreases expression EXP nefazodone results in decreased expression of RSRC2 mRNA CTD PMID:24136188 NCBI chr12:38,500,709...38,520,715
Ensembl chr12:38,500,770...38,520,707 		JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression EXP nefazodone results in decreased expression of RSRP1 mRNA CTD PMID:24136188 NCBI chr 5:152,431,448...152,435,202
Ensembl chr 5:152,431,478...152,435,126 		JBrowse link
G RT1-S3 RT1 class Ib, locus S3 decreases expression EXP nefazodone results in decreased expression of RT1-S3 mRNA CTD PMID:24136188 NCBI chr20:2,675,463...2,680,229 JBrowse link
G Rtcb RNA 2',3'-cyclic phosphate and 5'-OH ligase increases expression EXP nefazodone results in increased expression of RTCB mRNA CTD PMID:24136188 NCBI chr 7:19,795,393...19,814,875
Ensembl chr 7:19,795,393...19,814,875 		JBrowse link
G Rup2 urinary protein 2 decreases expression EXP nefazodone results in decreased expression of RUP2 mRNA CTD PMID:24136188 NCBI chr 8:43,547,875...43,551,456
Ensembl chr 8:43,549,809...43,700,211 		JBrowse link
G Ruvbl2 RuvB-like AAA ATPase 2 increases expression EXP nefazodone results in increased expression of RUVBL2 mRNA CTD PMID:24136188 NCBI chr 1:105,038,487...105,051,851
Ensembl chr 1:105,038,174...105,051,720 		JBrowse link
G Rwdd4 RWD domain containing 4 increases expression EXP nefazodone results in increased expression of RWDD4 mRNA CTD PMID:24136188 NCBI chr16:51,447,384...51,465,718
Ensembl chr16:51,447,385...51,465,759 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 decreases expression EXP nefazodone results in decreased expression of S1PR1 mRNA CTD PMID:24136188 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:205,900,836...206,328,689 		JBrowse link
G Saa4 serum amyloid A4 decreases expression EXP nefazodone results in decreased expression of SAA4 mRNA CTD PMID:24136188 NCBI chr 1:106,383,856...106,388,158
Ensembl chr 1:106,383,856...106,387,354 		JBrowse link
G Sall1 spalt-like transcription factor 1 increases expression EXP nefazodone results in increased expression of SALL1 mRNA CTD PMID:24136188 NCBI chr19:34,179,316...34,196,278
Ensembl chr19:34,181,078...34,196,278 		JBrowse link
G Samm50 SAMM50 sorting and assembly machinery component increases expression EXP nefazodone results in increased expression of SAMM50 mRNA CTD PMID:24136188 NCBI chr 7:117,197,460...117,221,668
Ensembl chr 7:117,197,381...117,224,581 		JBrowse link
G Sap18 Sin3A associated protein 18 increases expression EXP nefazodone results in increased expression of SAP18 mRNA CTD PMID:24136188 NCBI chr15:36,058,784...36,063,089
Ensembl chr10:87,156,914...87,158,257
Ensembl chr15:87,156,914...87,158,257 		JBrowse link
G Sap30l SAP30-like increases expression EXP nefazodone results in increased expression of SAP30L mRNA CTD PMID:24136188 NCBI chr10:42,480,201...42,488,139
Ensembl chr10:42,480,201...42,488,139 		JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B increases expression EXP nefazodone results in increased expression of SAR1B mRNA CTD PMID:24136188 NCBI chr10:36,525,365...36,555,009
Ensembl chr10:36,519,384...36,555,005 		JBrowse link
G Sardh sarcosine dehydrogenase decreases expression EXP nefazodone results in decreased expression of SARDH mRNA CTD PMID:24136188 NCBI chr 3:30,908,621...30,973,409
Ensembl chr 3:30,908,621...30,972,137 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of SARS1 mRNA CTD PMID:24136188 NCBI chr 2:198,753,673...198,769,411
Ensembl chr 2:198,753,675...198,769,365 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 decreases expression EXP nefazodone results in decreased expression of SAT1 mRNA CTD PMID:24136188 NCBI chr  X:44,008,089...44,011,376
Ensembl chr  X:44,006,781...44,011,374 		JBrowse link
G Scamp1 secretory carrier membrane protein 1 increases expression EXP nefazodone results in increased expression of SCAMP1 mRNA CTD PMID:24136188 NCBI chr 2:27,168,863...27,251,637
Ensembl chr 2:27,168,864...27,251,742 		JBrowse link
G Scamp4 secretory carrier membrane protein 4 increases expression EXP nefazodone results in increased expression of SCAMP4 mRNA CTD PMID:24136188 NCBI chr 7:9,752,193...9,764,614
Ensembl chr 7:9,752,193...9,778,736 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SCARB1 mRNA CTD PMID:32152650 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:36,957,496...37,023,980 		JBrowse link
G Scarb2 scavenger receptor class B, member 2 increases expression EXP nefazodone results in increased expression of SCARB2 mRNA CTD PMID:24136188 NCBI chr14:15,842,583...15,894,123
Ensembl chr14:15,842,515...15,896,671 		JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) increases expression EXP nefazodone results in increased expression of SCCPDH mRNA CTD PMID:24136188 NCBI chr13:93,932,086...93,953,840
Ensembl chr13:93,912,395...93,954,192 		JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of SCD1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SCD mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 affects activity ISO nefazodone affects the activity of SCN5A protein CTD PMID:26821276 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470 		JBrowse link
G Scp2 sterol carrier protein 2 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of SCP2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SCP2 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:128,008,125...128,110,043 		JBrowse link
G Sdc2 syndecan 2 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of SDC2 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SDC2 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 7:66,012,405...66,125,101
Ensembl chr 7:66,108,853...66,126,294 		JBrowse link
G Sdhc succinate dehydrogenase complex subunit C increases expression EXP nefazodone results in increased expression of SDHC mRNA CTD PMID:24136188 NCBI chr13:86,077,133...86,098,025
Ensembl chr13:86,077,134...86,098,044 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression EXP nefazodone results in increased expression of SDR42E1 mRNA CTD PMID:24136188 NCBI chr19:62,624,130...62,636,652
Ensembl chr19:62,624,150...62,636,756 		JBrowse link
G Sds serine dehydratase decreases expression EXP nefazodone results in decreased expression of SDS mRNA CTD PMID:24136188 NCBI chr12:41,743,796...41,751,108
Ensembl chr12:41,743,799...41,748,773 		JBrowse link
G Sec23a Sec23 homolog A, COPII coat complex component increases expression EXP nefazodone results in increased expression of SEC23A mRNA CTD PMID:24136188 NCBI chr 6:82,393,699...82,442,594
Ensembl chr 6:82,394,863...82,440,904 		JBrowse link
G Sec23b Sec23 homolog B, COPII coat complex component increases expression EXP nefazodone results in increased expression of SEC23B mRNA CTD PMID:24136188 NCBI chr 3:152,392,340...152,434,813
Ensembl chr 3:152,392,308...152,434,800 		JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component increases expression EXP nefazodone results in increased expression of SEC24D mRNA CTD PMID:24136188 NCBI chr 2:214,103,138...214,211,155
Ensembl chr 2:214,103,190...214,211,144 		JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor decreases expression EXP nefazodone results in decreased expression of SEC62 mRNA CTD PMID:24136188 NCBI chr 2:114,499,317...114,526,705
Ensembl chr 2:114,499,317...114,530,321 		JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator decreases expression EXP nefazodone results in decreased expression of SEC63 mRNA CTD PMID:24136188 NCBI chr20:47,827,291...47,896,248
Ensembl chr20:47,827,291...47,896,248 		JBrowse link
G Sectm1b secreted and transmembrane 1B decreases expression EXP nefazodone results in decreased expression of SECTM1B mRNA CTD PMID:24136188 NCBI chr10:106,822,397...106,832,105
Ensembl chr10:106,822,397...106,832,104 		JBrowse link
G Selenbp1 selenium binding protein 1 increases expression EXP nefazodone results in increased expression of SELENBP1 mRNA CTD PMID:24136188 NCBI chr 2:185,183,022...185,193,612
Ensembl chr 2:185,183,004...185,194,295 		JBrowse link
G Serf2 small EDRK-rich factor 2 decreases expression EXP nefazodone results in decreased expression of SERF2 mRNA CTD PMID:24136188 NCBI chr 3:128,880,681...128,884,457
Ensembl chr 3:128,880,681...128,884,457 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 increases expression EXP nefazodone results in increased expression of SERP1 mRNA CTD PMID:24136188 NCBI chr 2:144,907,204...144,911,187
Ensembl chr 2:144,907,205...144,911,187 		JBrowse link
G Serpina11 serpin family A member 11 decreases expression EXP nefazodone results in decreased expression of SERPINA11 mRNA CTD PMID:24136188 NCBI chr 6:128,668,030...128,677,476
Ensembl chr 6:128,668,034...128,677,454 		JBrowse link
G Serpina3c serine (or cysteine) proteinase inhibitor, clade A, member 3C decreases expression EXP nefazodone results in decreased expression of SERPINA3C mRNA CTD PMID:24136188 NCBI chr 6:129,007,578...129,014,988
Ensembl chr 6:128,829,577...129,014,971 		JBrowse link
G Serpina3n serpin family A member 3N decreases expression EXP nefazodone results in decreased expression of SERPINA3N mRNA CTD PMID:24136188 NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415 		JBrowse link
G Serpina4 serpin family A member 4 decreases expression EXP nefazodone results in decreased expression of SERPINA4 mRNA CTD PMID:24136188 NCBI chr 6:128,764,738...128,773,858
Ensembl chr 6:128,764,769...128,776,028 		JBrowse link
G Serpina6 serpin family A member 6 decreases expression EXP nefazodone results in decreased expression of SERPINA6 mRNA CTD PMID:24136188 NCBI chr 6:128,544,828...128,555,064
Ensembl chr 6:128,544,831...128,555,139 		JBrowse link
G Serpinb9 serpin family B member 9 decreases expression EXP nefazodone results in decreased expression of SERPINB9 mRNA CTD PMID:24136188 NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,629,392...31,651,974 		JBrowse link
G Serpind1 serpin family D member 1 decreases expression EXP nefazodone results in decreased expression of SERPIND1 mRNA CTD PMID:24136188 NCBI chr11:97,168,753...97,179,830
Ensembl chr11:97,168,754...97,179,755 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA
nefazodone results in increased expression of SERPINE1 mRNA 		CTD PMID:32152650 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Serpinf2 serpin family F member 2 decreases expression EXP nefazodone results in decreased expression of SERPINF2 mRNA CTD PMID:24136188 NCBI chr10:60,770,698...60,778,782
Ensembl chr10:60,770,698...60,778,996 		JBrowse link
G Serping1 serpin family G member 1 decreases expression EXP nefazodone results in decreased expression of SERPING1 mRNA CTD PMID:24136188 NCBI chr 3:90,249,410...90,259,299
Ensembl chr 3:90,249,423...90,258,717 		JBrowse link
G Sesn2 sestrin 2 decreases expression EXP nefazodone results in decreased expression of SESN2 mRNA CTD PMID:24136188 NCBI chr 5:149,986,304...150,005,255
Ensembl chr 5:149,986,317...150,005,255 		JBrowse link
G Set Set nuclear proto-oncogene increases expression EXP nefazodone results in increased expression of SET mRNA CTD PMID:24136188 NCBI chr 3:33,732,319...33,743,433 JBrowse link
G Setd4 SET domain containing 4 increases expression EXP nefazodone results in increased expression of SETD4 mRNA CTD PMID:24136188 NCBI chr11:46,315,340...46,344,024
Ensembl chr11:46,323,895...46,344,024 		JBrowse link
G Setd6 SET domain containing 6, protein lysine methyltransferase increases expression EXP nefazodone results in increased expression of SETD6 mRNA CTD PMID:24136188 NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515 		JBrowse link
G Sez6 seizure related 6 homolog decreases expression EXP nefazodone results in decreased expression of SEZ6 mRNA CTD PMID:24136188 NCBI chr10:63,317,065...63,366,733
Ensembl chr10:63,316,953...63,366,723 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 increases expression EXP nefazodone results in increased expression of SF3B4 mRNA CTD PMID:24136188 NCBI chr 2:186,421,667...186,426,419
Ensembl chr 2:186,421,636...186,426,833 		JBrowse link
G Sf3b5 splicing factor 3b, subunit 5 increases expression EXP nefazodone results in increased expression of SF3B5 mRNA CTD PMID:24136188 NCBI chr 1:9,177,189...9,177,901
Ensembl chr 1:9,177,098...9,177,900 		JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression EXP nefazodone results in increased expression of SFPQ mRNA CTD PMID:24136188 NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926 		JBrowse link
G Sfxn1 sideroflexin 1 increases expression EXP nefazodone results in increased expression of SFXN1 mRNA CTD PMID:24136188 NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456 		JBrowse link
G Sgf29 SAGA complex associated factor 29 increases expression EXP nefazodone results in increased expression of SGF29 mRNA CTD PMID:24136188 NCBI chr 1:190,668,803...190,702,500
Ensembl chr 1:190,669,028...190,717,906 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression EXP nefazodone results in decreased expression of SGK1 mRNA CTD PMID:24136188 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 increases expression EXP nefazodone results in increased expression of SGPP1 mRNA CTD PMID:24136188 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259 		JBrowse link
G Sh2d4a SH2 domain containing 4A decreases expression EXP nefazodone results in decreased expression of SH2D4A mRNA CTD PMID:24136188 NCBI chr16:26,106,721...26,176,069
Ensembl chr16:26,106,730...26,175,974 		JBrowse link
G Sh3bgrl SH3 domain binding glutamate rich protein like decreases expression EXP nefazodone results in decreased expression of SH3BGRL mRNA CTD PMID:24136188 NCBI chr  X:78,242,704...78,343,633
Ensembl chr  X:78,242,405...78,343,634 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 multiple interactions
increases expression 		ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SH3GLB1 mRNA
nefazodone results in increased expression of SH3GLB1 mRNA 		CTD PMID:32152650 NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:236,410,436...236,445,140 		JBrowse link
G Shc1 SHC adaptor protein 1 increases expression EXP nefazodone results in increased expression of SHC1 mRNA CTD PMID:24136188 NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 increases expression EXP nefazodone results in increased expression of SHMT1 mRNA CTD PMID:24136188 NCBI chr10:45,968,959...45,990,341
Ensembl chr10:45,960,434...45,997,326 		JBrowse link
G Sin3b SIN3 transcription regulator family member B increases expression EXP nefazodone results in increased expression of SIN3B mRNA CTD PMID:24136188 NCBI chr16:17,157,352...17,194,051
Ensembl chr16:17,157,352...17,270,664 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex increases expression EXP nefazodone results in increased expression of SKIC8 mRNA CTD PMID:24136188 NCBI chr 8:63,999,669...64,016,959
Ensembl chr 8:63,999,671...64,016,846 		JBrowse link
G Skp1 S-phase kinase-associated protein 1 increases expression EXP nefazodone results in increased expression of SKP1 mRNA CTD PMID:24136188 NCBI chr10:36,898,670...36,917,828
Ensembl chr10:36,903,078...36,918,308 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of SLC10A1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SLC10A1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944 		JBrowse link
G Slc10a7 solute carrier family 10, member 7 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SLC10A7 mRNA CTD PMID:33819548 NCBI chr19:46,087,440...46,311,753
Ensembl chr19:46,049,631...46,311,753 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 increases expression EXP nefazodone results in increased expression of SLC12A2 mRNA CTD PMID:24136188 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 increases expression EXP nefazodone results in increased expression of SLC16A7 mRNA CTD PMID:24136188 NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386 		JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression EXP nefazodone results in increased expression of SLC17A1 mRNA CTD PMID:24136188 NCBI chr17:41,647,332...41,683,078
Ensembl chr17:41,649,919...41,681,174 		JBrowse link
G Slc17a2 solute carrier family 17, member 2 decreases expression EXP nefazodone results in decreased expression of SLC17A2 mRNA CTD PMID:24136188 NCBI chr17:41,748,195...41,767,601
Ensembl chr17:41,748,195...41,764,180 		JBrowse link
G Slc17a3 solute carrier family 17 member 3 increases expression EXP nefazodone results in increased expression of SLC17A3 mRNA CTD PMID:24136188 NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,698,680...41,723,329 		JBrowse link
G Slc18b1 solute carrier family 18 member B1 increases expression EXP nefazodone results in increased expression of SLC18B1 mRNA CTD PMID:24136188 NCBI chr 1:23,447,462...23,490,043
Ensembl chr 1:23,447,462...23,489,962 		JBrowse link
G Slc19a2 solute carrier family 19 member 2 decreases expression EXP nefazodone results in decreased expression of SLC19A2 mRNA CTD PMID:24136188 NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 increases expression EXP nefazodone results in increased expression of SLC20A1 mRNA CTD PMID:24136188 NCBI chr 3:136,880,360...136,894,255
Ensembl chr 3:136,880,290...136,894,249 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of SLC22A1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SLC22A1 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a18 solute carrier family 22, member 18 increases expression EXP nefazodone results in increased expression of SLC22A18 mRNA CTD PMID:24136188 NCBI chr 1:208,100,032...208,124,382
Ensembl chr 1:208,101,136...208,124,380 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO nefazodone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP nefazodone results in increased expression of SLC22A5 mRNA CTD PMID:24136188 NCBI chr10:38,509,072...38,536,240
Ensembl chr10:38,509,072...38,536,077 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression EXP nefazodone results in decreased expression of SLC22A7 mRNA CTD PMID:24136188 NCBI chr 9:22,044,672...22,052,051
Ensembl chr 9:22,045,435...22,051,681 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP nefazodone results in decreased expression of SLC22A8 mRNA CTD PMID:24136188 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588 		JBrowse link
G Slc25a1 solute carrier family 25 member 1 decreases expression EXP nefazodone results in decreased expression of SLC25A1 mRNA CTD PMID:24136188 NCBI chr11:96,560,054...96,563,071
Ensembl chr11:96,560,041...96,565,052 		JBrowse link
G Slc25a17 solute carrier family 25 member 17 increases expression EXP nefazodone results in increased expression of SLC25A17 mRNA CTD PMID:24136188 NCBI chr 7:114,724,533...114,767,163
Ensembl chr 7:114,724,533...114,767,345 		JBrowse link
G Slc25a20 solute carrier family 25 member 20 increases expression EXP nefazodone results in increased expression of SLC25A20 mRNA CTD PMID:24136188 NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027 		JBrowse link
G Slc25a23 solute carrier family 25 member 23 decreases expression EXP nefazodone results in decreased expression of SLC25A23 mRNA CTD PMID:24136188 NCBI chr 9:1,969,633...1,985,365
Ensembl chr 9:1,969,357...1,985,365 		JBrowse link
G Slc25a25 solute carrier family 25 member 25 decreases expression EXP nefazodone results in decreased expression of SLC25A25 mRNA CTD PMID:24136188 NCBI chr 3:36,106,448...36,139,812
Ensembl chr 3:36,106,449...36,140,011 		JBrowse link
G Slc25a3 solute carrier family 25 member 3 increases expression EXP nefazodone results in increased expression of SLC25A3 mRNA CTD PMID:24136188 NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309 		JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP nefazodone results in decreased expression of SLC25A30 mRNA CTD PMID:24136188 NCBI chr15:57,486,346...57,508,981
Ensembl chr15:57,486,350...57,502,690 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 increases expression EXP nefazodone results in increased expression of SLC25A39 mRNA CTD PMID:24136188 NCBI chr10:87,862,630...87,867,626
Ensembl chr10:87,862,631...87,866,973 		JBrowse link
G Slc26a8 solute carrier family 26 member 8 increases expression EXP nefazodone results in increased expression of SLC26A8 mRNA CTD PMID:24136188 NCBI chr20:6,687,207...6,751,184
Ensembl chr20:6,699,445...6,751,184 		JBrowse link
G Slc28a2 solute carrier family 28 member 2 decreases expression EXP nefazodone results in decreased expression of SLC28A2 mRNA CTD PMID:24136188 NCBI chr 3:129,778,425...129,841,292
Ensembl chr 3:129,807,537...129,841,291 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 decreases expression EXP nefazodone results in decreased expression of SLC29A1 mRNA CTD PMID:24136188 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 decreases expression EXP nefazodone results in decreased expression of SLC2A2 mRNA CTD PMID:24136188 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression EXP nefazodone results in increased expression of SLC30A1 mRNA CTD PMID:24136188 NCBI chr13:106,022,019...106,025,892
Ensembl chr13:106,022,019...106,025,892 		JBrowse link
G Slc30a5 solute carrier family 30 member 5 increases expression EXP nefazodone results in increased expression of SLC30A5 mRNA CTD PMID:24136188 NCBI chr 2:33,679,800...33,710,025
Ensembl chr 2:33,679,800...33,712,596 		JBrowse link
G Slc33a1 solute carrier family 33 member 1 increases expression EXP nefazodone results in increased expression of SLC33A1 mRNA CTD PMID:24136188 NCBI chr 2:150,565,327...150,587,700
Ensembl chr 2:150,565,328...150,587,416 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 increases expression EXP nefazodone results in increased expression of SLC34A1 mRNA CTD PMID:24136188 NCBI chr17:9,224,010...9,238,983
Ensembl chr17:9,224,010...9,238,983 		JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP nefazodone results in decreased expression of SLC34A2 mRNA CTD PMID:24136188 NCBI chr14:62,123,313...62,153,020
Ensembl chr14:62,123,316...62,143,360 		JBrowse link
G Slc35b1 solute carrier family 35, member B1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SLC35B1 mRNA CTD PMID:33819548 NCBI chr10:80,824,972...80,832,048
Ensembl chr10:80,824,696...80,832,045 		JBrowse link
G Slc35e3 solute carrier family 35, member E3 increases expression EXP nefazodone results in increased expression of SLC35E3 mRNA CTD PMID:24136188 NCBI chr 7:55,222,962...55,236,022
Ensembl chr 7:55,219,998...55,236,035 		JBrowse link
G Slc39a8 solute carrier family 39 member 8 decreases expression EXP nefazodone results in decreased expression of SLC39A8 mRNA CTD PMID:24136188 NCBI chr 2:226,845,686...226,992,668
Ensembl chr 2:226,929,644...226,992,667 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression EXP nefazodone results in increased expression of SLC3A2 mRNA CTD PMID:24136188 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression EXP nefazodone results in increased expression of SLC40A1 mRNA CTD PMID:24136188 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460 		JBrowse link
G Slc43a1 solute carrier family 43 member 1 decreases expression EXP nefazodone results in decreased expression of SLC43A1 mRNA CTD PMID:24136188 NCBI chr 3:90,327,250...90,353,438
Ensembl chr 3:90,327,149...90,353,438 		JBrowse link
G Slc46a1 solute carrier family 46 member 1 decreases expression EXP nefazodone results in decreased expression of SLC46A1 mRNA CTD PMID:24136188 NCBI chr10:63,859,551...63,865,987
Ensembl chr10:63,859,504...63,866,869 		JBrowse link
G Slc48a1 solute carrier family 48 member 1 increases expression EXP nefazodone results in increased expression of SLC48A1 mRNA CTD PMID:24136188 NCBI chr 7:130,794,233...130,802,119
Ensembl chr 7:130,794,245...130,803,022 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP nefazodone results in increased expression of SLC4A2 mRNA CTD PMID:24136188 NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:11,628,862...11,645,402 		JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SLC51B mRNA CTD PMID:32152650 NCBI chr 8:74,827,047...74,835,109
Ensembl chr 8:74,827,047...74,835,109 		JBrowse link
G Slc66a2 solute carrier family 66 member 2 decreases expression EXP nefazodone results in decreased expression of SLC66A2 mRNA CTD PMID:24136188 NCBI chr18:75,976,000...76,014,651
Ensembl chr18:75,977,458...76,014,651 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 decreases expression EXP nefazodone results in decreased expression of SLC6A12 mRNA CTD PMID:24136188 NCBI chr 4:156,257,518...156,275,870
Ensembl chr 4:156,254,208...156,275,879 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 decreases expression EXP nefazodone results in decreased expression of SLC6A6 mRNA CTD PMID:24136188 NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression EXP nefazodone results in increased expression of SLC6A9 mRNA CTD PMID:24136188 NCBI chr 5:136,660,022...136,694,173
Ensembl chr 5:136,659,948...136,694,172 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases expression EXP nefazodone results in increased expression of SLCO1A2 mRNA CTD PMID:24136188 NCBI chr 4:176,441,104...176,495,846
Ensembl chr 4:176,441,104...176,495,816 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 decreases expression EXP nefazodone results in decreased expression of SLCO2A1 mRNA CTD PMID:24136188 NCBI chr 8:112,467,739...112,551,923
Ensembl chr 8:112,467,160...112,551,921 		JBrowse link
G Slfn3 schlafen 3 decreases expression EXP nefazodone results in decreased expression of SLFN3 mRNA CTD PMID:24136188 NCBI chr10:68,515,815...68,557,674 JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO nefazodone results in increased expression of SLPI mRNA CTD PMID:32816093 NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822 		JBrowse link
G Sltm SAFB-like, transcription modulator increases expression EXP nefazodone results in increased expression of SLTM mRNA CTD PMID:24136188 NCBI chr 8:80,096,555...80,142,668
Ensembl chr 8:80,097,652...80,142,671 		JBrowse link
G Smagp small cell adhesion glycoprotein decreases expression EXP nefazodone results in decreased expression of SMAGP mRNA CTD PMID:24136188 NCBI chr 7:133,599,043...133,617,492
Ensembl chr 7:133,599,043...133,616,642 		JBrowse link
G Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 increases expression EXP nefazodone results in increased expression of SMARCB1 mRNA CTD PMID:24136188 NCBI chr20:12,740,105...12,763,054
Ensembl chr20:12,740,943...12,763,055 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 decreases expression EXP nefazodone results in decreased expression of SMC6 mRNA CTD PMID:24136188 NCBI chr 6:39,697,810...39,752,275
Ensembl chr 6:39,697,811...39,752,279 		JBrowse link
G Smim26 small integral membrane protein 26 increases expression EXP nefazodone results in increased expression of SMIM26 mRNA CTD PMID:24136188 NCBI chr 3:152,443,397...152,445,102
Ensembl chr 3:152,443,579...152,445,447 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 decreases expression EXP nefazodone results in decreased expression of SMOC1 mRNA CTD PMID:24136188 NCBI chr 6:106,432,592...106,593,956
Ensembl chr 6:106,432,603...106,593,956 		JBrowse link
G Snap29 synaptosome associated protein 29 increases expression EXP nefazodone results in increased expression of SNAP29 mRNA CTD PMID:24136188 NCBI chr11:97,082,721...97,113,195
Ensembl chr11:97,082,739...97,113,195 		JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 increases expression EXP nefazodone results in increased expression of SNRNP25 mRNA CTD PMID:24136188 NCBI chr10:15,924,932...15,928,279
Ensembl chr10:15,924,940...15,928,252 		JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 decreases expression EXP nefazodone results in decreased expression of SNRNP70 mRNA CTD PMID:24136188 NCBI chr 1:104,992,518...105,012,851
Ensembl chr 1:104,992,442...105,012,851 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 increases expression EXP nefazodone results in increased expression of SNRPB mRNA CTD PMID:24136188 NCBI chr 3:137,824,870...137,832,479
Ensembl chr 3:137,824,683...137,832,515 		JBrowse link
G Snrpc small nuclear ribonucleoprotein polypeptide C increases expression EXP nefazodone results in increased expression of SNRPC mRNA CTD PMID:24136188 NCBI chr20:5,890,229...5,908,410
Ensembl chr20:5,890,229...5,908,410 		JBrowse link
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide increases expression EXP nefazodone results in increased expression of SNRPD3 mRNA CTD PMID:24136188 NCBI chr20:13,129,555...13,145,100
Ensembl chr20:13,109,294...13,145,763 		JBrowse link
G Snrpg small nuclear ribonucleoprotein polypeptide G increases expression EXP nefazodone results in increased expression of SNRPG mRNA CTD PMID:24136188 NCBI chr 4:120,369,676...120,377,263
Ensembl chr 4:120,369,685...120,377,261
Ensembl chr  X:120,369,685...120,377,261 		JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 increases expression EXP nefazodone results in increased expression of SNU13 mRNA CTD PMID:24136188 NCBI chr 7:115,445,415...115,451,008
Ensembl chr 1:269,702,002...269,703,004
Ensembl chr 7:269,702,002...269,703,004 		JBrowse link
G Snx2 sorting nexin 2 increases expression EXP nefazodone results in increased expression of SNX2 mRNA CTD PMID:24136188 NCBI chr18:48,800,594...48,842,158
Ensembl chr18:48,800,583...48,842,474 		JBrowse link
G Snx24 sorting nexin 24 decreases expression EXP nefazodone results in decreased expression of SNX24 mRNA CTD PMID:24136188 NCBI chr18:48,869,804...49,024,352
Ensembl chr18:48,869,882...49,024,350 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression EXP nefazodone results in decreased expression of SOCS2 mRNA CTD PMID:24136188 NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases expression 		EXP
ISO 		nefazodone results in increased expression of SOD2 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SOD2 mRNA
nefazodone results in decreased expression of SOD2 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sord sorbitol dehydrogenase increases expression EXP nefazodone results in increased expression of SORD mRNA CTD PMID:24136188 NCBI chr 3:129,638,282...129,669,727
Ensembl chr 3:129,638,302...129,686,100 		JBrowse link
G Sorl1 sortilin related receptor 1 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SORL1 mRNA CTD PMID:33819548 NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:51,238,722...51,401,446 		JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression EXP nefazodone results in decreased expression of SPARC mRNA CTD PMID:24136188 NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268 		JBrowse link
G Spg21 SPG21 abhydrolase domain containing, maspardin increases expression EXP nefazodone results in increased expression of SPG21 mRNA CTD PMID:24136188 NCBI chr 8:74,876,136...74,903,676
Ensembl chr 8:74,876,136...74,903,676 		JBrowse link
G Sphk2 sphingosine kinase 2 increases expression EXP nefazodone results in increased expression of SPHK2 mRNA CTD PMID:24136188 NCBI chr 1:105,317,332...105,324,985
Ensembl chr 1:105,317,333...105,321,637 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 decreases expression EXP nefazodone results in decreased expression of SPINK1 mRNA CTD PMID:24136188 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545 		JBrowse link
G Spryd4 SPRY domain containing 4 increases expression EXP nefazodone results in increased expression of SPRYD4 mRNA CTD PMID:24136188 NCBI chr 7:1,217,984...1,222,231
Ensembl chr 7:1,218,122...1,219,942 		JBrowse link
G Spryd7 SPRY domain containing 7 increases expression EXP nefazodone results in increased expression of SPRYD7 mRNA CTD PMID:24136188 NCBI chr15:39,883,237...39,903,770
Ensembl chr15:39,883,238...39,903,674 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases expression EXP nefazodone results in increased expression of SPTAN1 mRNA CTD PMID:24136188 NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:33,607,210...33,703,889 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A decreases expression EXP nefazodone results in decreased expression of SPTSSA mRNA CTD PMID:24136188 NCBI chr 6:77,879,931...77,891,344
Ensembl chr 6:77,879,941...77,891,403 		JBrowse link
G Sqstm1 sequestosome 1 increases expression
multiple interactions 		EXP
ISO 		nefazodone results in increased expression of SQSTM1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SQSTM1 mRNA 		CTD PMID:24136188 PMID:32152650 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases expression EXP nefazodone results in decreased expression of SRD5A1 mRNA CTD PMID:24136188 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
multiple interactions 		EXP
ISO 		nefazodone results in decreased expression of SREBF1 mRNA
[Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of SREBF1 mRNA 		CTD PMID:24136188 PMID:33819548 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164 		JBrowse link
G Srgn serglycin decreases expression EXP nefazodone results in decreased expression of SRGN mRNA CTD PMID:24136188 NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327 		JBrowse link
G Srm spermidine synthase increases expression EXP nefazodone results in increased expression of SRM mRNA CTD PMID:24136188 NCBI chr 5:164,309,002...164,312,203
Ensembl chr 5:164,308,991...164,332,705 		JBrowse link
G Srp72 signal recognition particle 72 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of SRP72 mRNA CTD PMID:33819548 NCBI chr14:31,522,424...31,549,978
Ensembl chr14:31,522,963...31,550,151 		JBrowse link
G Srr serine racemase decreases expression EXP nefazodone results in decreased expression of SRR mRNA CTD PMID:24136188 NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100 		JBrowse link
G Srrt serrate, RNA effector molecule increases expression EXP nefazodone results in increased expression of SRRT mRNA CTD PMID:24136188 NCBI chr12:25,027,883...25,042,847
Ensembl chr12:25,029,334...25,042,845 		JBrowse link
G Srsf11 serine and arginine rich splicing factor 11 decreases expression EXP nefazodone results in decreased expression of SRSF11 mRNA CTD PMID:24136188 NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499 		JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 increases expression EXP nefazodone results in increased expression of SRSF4 mRNA CTD PMID:24136188 NCBI chr 5:149,345,538...149,373,309
Ensembl chr 5:149,345,422...149,374,609 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression EXP nefazodone results in increased expression of SRXN1 mRNA CTD PMID:24136188 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 increases expression EXP nefazodone results in increased expression of SSBP1 mRNA CTD PMID:24136188 NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700 		JBrowse link
G Ssx2ip SSX family member 2 interacting protein decreases expression EXP nefazodone results in decreased expression of SSX2IP mRNA CTD PMID:24136188 NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017 		JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression EXP nefazodone results in increased expression of ST13 mRNA CTD PMID:24136188 NCBI chr 7:114,769,758...114,805,877
Ensembl chr 7:114,769,759...114,805,941 		JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 decreases expression EXP nefazodone results in decreased expression of ST6GAL1 mRNA CTD PMID:24136188 NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415 		JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP nefazodone results in decreased expression of STAC3 mRNA CTD PMID:24136188 NCBI chr 7:65,227,151...65,235,884
Ensembl chr 7:65,228,352...65,235,878 		JBrowse link
G Stag1 STAG1 cohesin complex component decreases expression EXP nefazodone results in decreased expression of STAG1 mRNA CTD PMID:24136188 NCBI chr 8:110,057,981...110,443,666
Ensembl chr 8:110,058,056...110,443,665 		JBrowse link
G Stard3nl STARD3 N-terminal like increases expression EXP nefazodone results in increased expression of STARD3NL mRNA CTD PMID:24136188 NCBI chr17:50,278,859...50,312,864
Ensembl chr17:50,278,894...50,312,866 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 decreases expression EXP nefazodone results in decreased expression of STAT2 mRNA CTD PMID:24136188 NCBI chr 7:1,287,025...1,302,858
Ensembl chr 7:1,287,024...1,303,459 		JBrowse link
G Stbd1 starch binding domain 1 increases expression EXP nefazodone results in increased expression of STBD1 mRNA CTD PMID:24136188 NCBI chr14:15,754,769...15,758,174
Ensembl chr14:15,754,644...15,761,659 		JBrowse link
G Steap3 STEAP3 metalloreductase decreases expression EXP nefazodone results in decreased expression of STEAP3 mRNA CTD PMID:24136188 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:33,904,710...33,950,080 		JBrowse link
G Steap4 STEAP4 metalloreductase decreases expression EXP nefazodone results in decreased expression of STEAP4 mRNA CTD PMID:24136188 NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:27,009,584...27,067,105 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression EXP nefazodone results in increased expression of STIP1 mRNA CTD PMID:24136188 NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654 		JBrowse link
G Stk24 serine/threonine kinase 24 increases expression EXP nefazodone results in increased expression of STK24 mRNA CTD PMID:24136188 NCBI chr15:104,770,556...104,866,524
Ensembl chr15:104,773,569...104,865,975 		JBrowse link
G Stoml2 stomatin like 2 increases expression EXP nefazodone results in increased expression of STOML2 mRNA CTD PMID:24136188 NCBI chr 5:62,052,042...62,055,639
Ensembl chr 5:62,052,045...62,055,670 		JBrowse link
G Strap serine/threonine kinase receptor associated protein increases expression EXP nefazodone results in increased expression of STRAP mRNA CTD PMID:24136188 NCBI chr 4:172,377,325...172,391,573
Ensembl chr 4:172,377,305...172,392,436 		JBrowse link
G Stx12 syntaxin 12 increases expression EXP nefazodone results in increased expression of STX12 mRNA CTD PMID:24136188 NCBI chr 5:150,347,554...150,376,426
Ensembl chr 5:150,334,836...150,376,346 		JBrowse link
G Stx7 syntaxin 7 decreases expression EXP nefazodone results in decreased expression of STX7 mRNA CTD PMID:24136188 NCBI chr 1:23,016,330...23,056,579
Ensembl chr 1:23,016,336...23,056,465 		JBrowse link
G Sulf2 sulfatase 2 decreases expression EXP nefazodone results in decreased expression of SULF2 mRNA CTD PMID:24136188 NCBI chr 3:175,241,322...175,323,808
Ensembl chr 3:175,241,322...175,323,651 		JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases expression EXP nefazodone results in increased expression of SULT1B1 mRNA CTD PMID:24136188 NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549 		JBrowse link
G Sult1c2a sulfotransferase family 1C member 2A decreases expression EXP nefazodone results in decreased expression of SULT1C2A mRNA CTD PMID:24136188 NCBI chr 9:7,075,873...7,103,316
Ensembl chr 9:7,066,905...7,244,132 		JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 decreases expression EXP nefazodone results in decreased expression of SULT1C3 mRNA CTD PMID:24136188 NCBI chr 9:7,548,839...7,594,299
Ensembl chr 9:7,548,622...7,594,295 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression
multiple interactions 		ISO nefazodone results in decreased expression of SULT2A1 mRNA
[nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of SULT2A1 mRNA 		CTD PMID:32152650 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Sult2a6 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6 increases expression EXP nefazodone results in increased expression of SULT2A6 mRNA CTD PMID:24136188 NCBI chr 1:84,046,685...84,097,808
Ensembl chr 1:84,046,685...84,097,808 		JBrowse link
G Sumf2 sulfatase modifying factor 2 increases expression EXP nefazodone results in increased expression of SUMF2 mRNA CTD PMID:24136188 NCBI chr12:32,489,671...32,507,941
Ensembl chr12:32,489,671...32,507,928 		JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 increases expression EXP nefazodone results in increased expression of SUN2 mRNA CTD PMID:24136188 NCBI chr 7:113,155,766...113,172,950
Ensembl chr 7:113,155,766...113,172,940 		JBrowse link
G Suox sulfite oxidase decreases expression EXP nefazodone results in decreased expression of SUOX mRNA CTD PMID:24136188 NCBI chr 7:1,687,666...1,691,759
Ensembl chr 7:1,687,666...1,690,235 		JBrowse link
G Svil supervillin decreases expression EXP nefazodone results in decreased expression of SVIL mRNA CTD PMID:24136188 NCBI chr17:57,343,910...57,539,508
Ensembl chr17:57,343,910...57,462,660 		JBrowse link
G Swi5 SWI5 homologous recombination repair protein increases expression EXP nefazodone results in increased expression of SWI5 mRNA CTD PMID:24136188 NCBI chr 3:35,972,436...35,981,658
Ensembl chr 3:35,972,436...35,981,554 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein increases expression EXP nefazodone results in increased expression of SYNCRIP mRNA CTD PMID:24136188 NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:98,282,358...98,315,386 		JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression EXP nefazodone results in decreased expression of SYNE2 mRNA CTD PMID:24136188 NCBI chr 6:100,272,729...100,586,364
Ensembl chr 6:100,272,729...100,583,723 		JBrowse link
G Syngr2 synaptogyrin 2 increases expression EXP nefazodone results in increased expression of SYNGR2 mRNA CTD PMID:24136188 NCBI chr10:103,528,599...103,533,167
Ensembl chr10:103,528,607...103,533,162 		JBrowse link
G Synj2bp synaptojanin 2 binding protein decreases expression EXP nefazodone results in decreased expression of SYNJ2BP mRNA CTD PMID:24136188 NCBI chr 6:106,920,970...106,958,653
Ensembl chr 6:106,920,970...106,966,543 		JBrowse link
G Synrg synergin, gamma decreases expression EXP nefazodone results in decreased expression of SYNRG mRNA CTD PMID:24136188 NCBI chr10:69,346,154...69,428,714
Ensembl chr10:69,322,114...69,428,714 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 increases expression EXP nefazodone results in increased expression of TAF9 mRNA CTD PMID:24136188 NCBI chr 2:33,528,388...33,532,395
Ensembl chr 2:33,531,368...33,536,078 		JBrowse link
G Tardbp TAR DNA binding protein increases expression EXP nefazodone results in increased expression of TARDBP mRNA CTD PMID:24136188 NCBI chr 5:164,330,452...164,348,435
Ensembl chr 5:164,334,924...164,345,204 		JBrowse link
G Tatdn2 TatD DNase domain containing 2 increases expression EXP nefazodone results in increased expression of TATDN2 mRNA CTD PMID:24136188 NCBI chr 4:148,400,454...148,416,501
Ensembl chr 4:148,400,492...148,416,501 		JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression EXP nefazodone results in increased expression of TBC1D15 mRNA CTD PMID:24136188 NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303 		JBrowse link
G Tbc1d17 TBC1 domain family, member 17 increases expression EXP nefazodone results in increased expression of TBC1D17 mRNA CTD PMID:24136188 NCBI chr 1:104,461,266...104,469,615
Ensembl chr 1:104,461,267...104,469,489 		JBrowse link
G Tbc1d8 TBC1 domain family, member 8 decreases expression EXP nefazodone results in decreased expression of TBC1D8 mRNA CTD PMID:24136188 NCBI chr 9:49,147,109...49,257,140
Ensembl chr 9:49,147,109...49,257,118 		JBrowse link
G Tbcb tubulin folding cofactor B increases expression EXP nefazodone results in increased expression of TBCB mRNA CTD PMID:24136188 NCBI chr 1:94,605,100...94,610,949
Ensembl chr 1:94,605,101...94,610,949 		JBrowse link
G Tbce tubulin folding cofactor E increases expression EXP nefazodone results in increased expression of TBCE mRNA CTD PMID:24136188 NCBI chr17:55,983,627...56,031,578
Ensembl chr17:55,985,707...56,032,302 		JBrowse link
G Tbk1 TANK-binding kinase 1 increases expression EXP nefazodone results in increased expression of TBK1 mRNA CTD PMID:24136188 NCBI chr 7:58,963,319...58,996,357
Ensembl chr 7:58,963,325...58,996,357 		JBrowse link
G Tcea1 transcription elongation factor A1 increases expression EXP nefazodone results in increased expression of TCEA1 mRNA CTD PMID:24136188 NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156 		JBrowse link
G Tcp1 t-complex 1 increases expression EXP nefazodone results in increased expression of TCP1 mRNA CTD PMID:24136188 NCBI chr 1:50,376,848...50,384,527
Ensembl chr 1:50,376,848...50,384,527 		JBrowse link
G Tdg thymine-DNA glycosylase increases expression EXP nefazodone results in increased expression of TDG mRNA CTD PMID:24136188 NCBI chr 7:22,965,388...22,990,311
Ensembl chr 7:22,965,388...22,985,100 		JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression EXP nefazodone results in increased expression of TEF mRNA CTD PMID:24136188 NCBI chr 7:115,197,180...115,221,930
Ensembl chr 7:115,193,282...115,221,928 		JBrowse link
G Tefm transcription elongation factor, mitochondrial increases expression EXP nefazodone results in increased expression of TEFM mRNA CTD PMID:24136188 NCBI chr10:65,617,547...65,622,042
Ensembl chr10:65,617,550...65,622,042 		JBrowse link
G Tent2 terminal nucleotidyltransferase 2 decreases expression EXP nefazodone results in decreased expression of TENT2 mRNA CTD PMID:24136188 NCBI chr 2:26,115,150...26,167,465
Ensembl chr 2:26,115,240...26,167,113 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B increases expression EXP nefazodone results in increased expression of TENT4B mRNA CTD PMID:24136188 NCBI chr19:34,984,244...35,042,423
Ensembl chr19:34,980,296...35,042,399 		JBrowse link
G Tent5a terminal nucleotidyltransferase 5A decreases expression EXP nefazodone results in decreased expression of TENT5A mRNA CTD PMID:24136188 NCBI chr 8:95,102,349...95,109,100
Ensembl chr 8:95,105,412...95,109,100 		JBrowse link
G Tex261 testis expressed 261 increases expression EXP nefazodone results in increased expression of TEX261 mRNA CTD PMID:24136188 NCBI chr 4:117,813,050...117,818,408
Ensembl chr 4:117,811,176...117,819,180 		JBrowse link
G Tex264 testis expressed 264, ER-phagy receptor increases expression EXP nefazodone results in increased expression of TEX264 mRNA CTD PMID:24136188 NCBI chr 8:116,174,517...116,201,578
Ensembl chr 8:116,174,518...116,201,667 		JBrowse link
G Tf transferrin decreases expression EXP nefazodone results in decreased expression of TF mRNA CTD PMID:24136188 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400 		JBrowse link
G Tfam transcription factor A, mitochondrial increases expression EXP nefazodone results in increased expression of TFAM mRNA CTD PMID:24136188 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877 		JBrowse link
G Tfb2m transcription factor B2, mitochondrial increases expression EXP nefazodone results in increased expression of TFB2M mRNA CTD PMID:24136188 NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594 		JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 increases expression EXP nefazodone results in increased expression of TFE3 mRNA CTD PMID:24136188 NCBI chr  X:17,401,466...17,414,829
Ensembl chr  X:17,401,466...17,414,685 		JBrowse link
G Tfpi tissue factor pathway inhibitor multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TFPI mRNA CTD PMID:33819548 NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742 		JBrowse link
G Tfrc transferrin receptor increases expression EXP nefazodone results in increased expression of TFRC mRNA CTD PMID:24136188 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP nefazodone results in decreased expression of TGFBI mRNA CTD PMID:24136188 NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471 		JBrowse link
G Tgm2 transglutaminase 2 decreases expression EXP nefazodone results in decreased expression of TGM2 mRNA CTD PMID:24136188 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240 		JBrowse link
G Thnsl2 threonine synthase-like 2 decreases expression EXP nefazodone results in decreased expression of THNSL2 mRNA CTD PMID:24136188 NCBI chr 4:104,671,305...104,691,084
Ensembl chr 4:104,670,925...104,691,959 		JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP nefazodone results in decreased expression of THRSP mRNA CTD PMID:24136188 NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827 		JBrowse link
G Thumpd3 THUMP domain containing 3 increases expression EXP nefazodone results in increased expression of THUMPD3 mRNA CTD PMID:24136188 NCBI chr 4:147,741,288...147,764,254
Ensembl chr 4:147,741,309...147,765,579 		JBrowse link
G Timm10 translocase of inner mitochondrial membrane 10 increases expression EXP nefazodone results in increased expression of TIMM10 mRNA CTD PMID:24136188 NCBI chr 3:90,315,048...90,318,613
Ensembl chr 3:90,315,092...90,318,614 		JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B increases expression EXP nefazodone results in increased expression of TIMM10B mRNA CTD PMID:24136188 NCBI chr 1:169,392,355...169,395,201
Ensembl chr 1:169,392,177...169,395,205 		JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 increases expression EXP nefazodone results in increased expression of TIMM13 mRNA CTD PMID:24136188 NCBI chr 7:9,459,490...9,460,849
Ensembl chr 7:9,459,582...9,460,862 		JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A increases expression EXP nefazodone results in increased expression of TIMM17A mRNA CTD PMID:24136188 NCBI chr13:49,282,918...49,296,363
Ensembl chr13:49,282,918...49,307,904 		JBrowse link
G Timm29 translocase of inner mitochondrial membrane 29 increases expression EXP nefazodone results in increased expression of TIMM29 mRNA CTD PMID:24136188 NCBI chr 8:28,421,370...28,424,339
Ensembl chr 8:28,421,370...28,424,339 		JBrowse link
G Timm8a1 translocase of inner mitochondrial membrane 8A1 increases expression EXP nefazodone results in increased expression of TIMM8A1 mRNA CTD PMID:24136188 NCBI chr  X:102,011,206...102,015,444
Ensembl chr  X:102,011,206...102,015,444 		JBrowse link
G Timm8b translocase of inner mitochondrial membrane 8 homolog B increases expression EXP nefazodone results in increased expression of TIMM8B mRNA CTD PMID:24136188 NCBI chr 8:59,850,737...59,852,117
Ensembl chr 8:59,850,728...59,852,962 		JBrowse link
G Timm9 translocase of inner mitochondrial membrane 9 increases expression EXP nefazodone results in increased expression of TIMM9 mRNA CTD PMID:24136188 NCBI chr 6:95,346,065...95,358,895
Ensembl chr 6:95,346,065...95,358,895 		JBrowse link
G Tjp2 tight junction protein 2 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of TJP2 mRNA CTD PMID:33819548 NCBI chr 1:231,136,218...231,264,750
Ensembl chr 1:231,136,243...231,264,750 		JBrowse link
G Tkt transketolase increases expression EXP nefazodone results in increased expression of TKT mRNA CTD PMID:24136188 NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431 		JBrowse link
G Tle5 TLE family member 5, transcriptional modulator decreases expression EXP nefazodone results in decreased expression of TLE5 mRNA CTD PMID:24136188 NCBI chr 7:8,794,123...8,801,056
Ensembl chr 7:8,793,796...8,801,054 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TLR4 mRNA CTD PMID:33819548 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tm2d1 TM2 domain containing 1 increases expression EXP nefazodone results in increased expression of TM2D1 mRNA CTD PMID:24136188 NCBI chr 5:118,136,299...118,177,639
Ensembl chr 5:118,136,299...118,170,283 		JBrowse link
G Tm2d3 TM2 domain containing 3 increases expression EXP nefazodone results in increased expression of TM2D3 mRNA CTD PMID:24136188 NCBI chr 1:128,677,680...128,687,580
Ensembl chr 1:128,677,629...128,687,580 		JBrowse link
G Tm9sf3 transmembrane 9 superfamily member 3 increases expression EXP nefazodone results in increased expression of TM9SF3 mRNA CTD PMID:24136188 NCBI chr 1:249,981,458...250,034,247
Ensembl chr 1:249,981,458...250,034,247 		JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 decreases expression EXP nefazodone results in decreased expression of TMCC2 mRNA CTD PMID:24136188 NCBI chr13:46,346,177...46,383,862
Ensembl chr13:46,346,177...46,383,862 		JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 increases expression EXP nefazodone results in increased expression of TMCO1 mRNA CTD PMID:24136188 NCBI chr13:81,993,172...82,016,496
Ensembl chr13:81,993,097...82,017,201 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 increases expression EXP nefazodone results in increased expression of TMED2 mRNA CTD PMID:24136188 NCBI chr12:37,713,522...37,722,606
Ensembl chr12:37,713,529...37,722,606 		JBrowse link
G Tmed9 transmembrane p24 trafficking protein 9 increases expression EXP nefazodone results in increased expression of TMED9 mRNA CTD PMID:24136188 NCBI chr17:9,034,797...9,039,311
Ensembl chr17:9,034,823...9,039,319 		JBrowse link
G Tmem106b transmembrane protein 106B increases expression EXP nefazodone results in increased expression of TMEM106B mRNA CTD PMID:24136188 NCBI chr 4:42,294,074...42,313,426
Ensembl chr 4:42,294,101...42,313,407 		JBrowse link
G Tmem11 transmembrane protein 11 increases expression EXP nefazodone results in increased expression of TMEM11 mRNA CTD PMID:24136188 NCBI chr10:46,042,251...46,057,065
Ensembl chr 6:125,690,543...125,691,404
Ensembl chr10:125,690,543...125,691,404 		JBrowse link
G Tmem126a transmembrane protein 126A increases expression EXP nefazodone results in increased expression of TMEM126A mRNA CTD PMID:24136188 NCBI chr 1:153,837,015...153,843,192
Ensembl chr 1:153,835,236...153,843,160 		JBrowse link
G Tmem134 transmembrane protein 134 increases expression EXP nefazodone results in increased expression of TMEM134 mRNA CTD PMID:24136188 NCBI chr 1:210,848,761...210,857,735
Ensembl chr 1:210,848,578...210,858,861 		JBrowse link
G Tmem140 transmembrane protein 140 decreases expression EXP nefazodone results in decreased expression of TMEM140 mRNA CTD PMID:24136188 NCBI chr 4:64,503,621...64,514,620
Ensembl chr 4:64,500,439...64,521,990 		JBrowse link
G Tmem147 transmembrane protein 147 increases expression EXP nefazodone results in increased expression of TMEM147 mRNA CTD PMID:24136188 NCBI chr 1:95,104,448...95,106,268
Ensembl chr 1:95,104,452...95,106,283 		JBrowse link
G Tmem14c transmembrane protein 14C increases expression EXP nefazodone results in increased expression of TMEM14C mRNA CTD PMID:24136188 NCBI chr17:23,939,501...23,945,622
Ensembl chr17:23,939,509...23,959,055 		JBrowse link
G Tmem176a transmembrane protein 176A decreases expression EXP nefazodone results in decreased expression of TMEM176A mRNA CTD PMID:24136188 NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:79,101,857...79,111,175 		JBrowse link
G Tmem205 transmembrane protein 205 increases expression EXP nefazodone results in increased expression of TMEM205 mRNA CTD PMID:24136188 NCBI chr 8:28,728,172...28,733,908
Ensembl chr 8:28,728,172...28,733,908 		JBrowse link
G Tmem208 transmembrane protein 208 increases expression EXP nefazodone results in increased expression of TMEM208 mRNA CTD PMID:24136188 NCBI chr19:50,113,494...50,116,210
Ensembl chr19:50,113,510...50,124,153 		JBrowse link
G Tmem259 transmembrane protein 259 increases expression EXP nefazodone results in increased expression of TMEM259 mRNA CTD PMID:24136188 NCBI chr 7:10,374,804...10,381,566
Ensembl chr 7:10,373,119...10,381,566 		JBrowse link
G Tmem33 transmembrane protein 33 increases expression EXP nefazodone results in increased expression of TMEM33 mRNA CTD PMID:24136188 NCBI chr14:41,242,358...41,264,586
Ensembl chr14:41,242,358...41,264,586 		JBrowse link
G Tmem38b transmembrane protein 38B increases expression EXP nefazodone results in increased expression of TMEM38B mRNA CTD PMID:24136188 NCBI chr 5:73,255,662...73,291,383
Ensembl chr 5:73,255,632...73,292,384 		JBrowse link
G Tmem41a transmembrane protein 41a increases expression EXP nefazodone results in increased expression of TMEM41A mRNA CTD PMID:24136188 NCBI chr11:92,588,497...92,595,105
Ensembl chr11:92,588,489...92,595,715 		JBrowse link
G Tmem60 transmembrane protein 60 increases expression EXP nefazodone results in increased expression of TMEM60 mRNA CTD PMID:24136188 NCBI chr 4:15,102,168...15,107,023
Ensembl chr 4:15,100,348...15,107,139 		JBrowse link
G Tmem62 transmembrane protein 62 increases expression EXP nefazodone results in increased expression of TMEM62 mRNA CTD PMID:24136188 NCBI chr 3:128,380,366...128,415,583
Ensembl chr 3:128,375,500...128,415,583 		JBrowse link
G Tmem69 transmembrane protein 69 increases expression EXP nefazodone results in increased expression of TMEM69 mRNA CTD PMID:24136188 NCBI chr 5:135,241,557...135,247,323
Ensembl chr 5:135,241,560...135,247,215 		JBrowse link
G Tmem9b TMEM9 domain family, member B increases expression EXP nefazodone results in increased expression of TMEM9B mRNA CTD PMID:24136188 NCBI chr 1:173,199,225...173,218,674
Ensembl chr 1:173,200,869...173,218,053 		JBrowse link
G Tmsb4x thymosin beta 4, X-linked decreases expression EXP nefazodone results in decreased expression of TMSB4X mRNA CTD PMID:24136188 NCBI chr  X:30,761,611...30,763,612
Ensembl chr  X:30,761,612...30,763,613 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 increases expression EXP nefazodone results in increased expression of TMX1 mRNA CTD PMID:24136188 NCBI chr 6:94,696,699...94,707,751
Ensembl chr 6:94,696,358...94,708,618 		JBrowse link
G Tmx2 thioredoxin-related transmembrane protein 2 increases expression EXP nefazodone results in increased expression of TMX2 mRNA CTD PMID:24136188 NCBI chr 3:90,161,628...90,169,278
Ensembl chr 3:90,160,930...90,169,278 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP 		[IFNG protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to nefazodone CTD PMID:19362101 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TNFRSF10A mRNA CTD PMID:33819548 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:51,250,112...51,278,082 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression EXP nefazodone results in increased expression of TNFRSF1A mRNA CTD PMID:24136188 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in decreased expression of TNFSF10 mRNA CTD PMID:33819548 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of TNFSF11 mRNA CTD PMID:33819548 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479 		JBrowse link
G Tomm20 translocase of outer mitochondrial membrane 20 increases expression EXP nefazodone results in increased expression of TOMM20 mRNA CTD PMID:24136188 NCBI chr19:71,822,429...71,832,420
Ensembl chr19:71,822,411...71,832,510 		JBrowse link
G Tomm5 translocase of outer mitochondrial membrane 5 increases expression EXP nefazodone results in increased expression of TOMM5 mRNA CTD PMID:24136188 NCBI chr 5:64,158,026...64,160,857 JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 increases expression EXP nefazodone results in increased expression of TOMM70A mRNA CTD PMID:24136188 NCBI chr11:56,847,837...56,886,302
Ensembl chr11:56,846,334...56,886,320 		JBrowse link
G Tor1a torsin family 1, member A increases expression EXP nefazodone results in increased expression of TOR1A mRNA CTD PMID:24136188 NCBI chr 3:34,648,421...34,655,453
Ensembl chr 3:34,648,422...34,655,417 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression EXP nefazodone results in decreased expression of TP53I3 mRNA CTD PMID:24136188 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Tp53inp2 tumor protein p53 inducible nuclear protein 2 decreases expression EXP nefazodone results in decreased expression of TP53INP2 mRNA CTD PMID:24136188 NCBI chr 3:164,341,618...164,350,270
Ensembl chr 3:164,343,205...164,350,225 		JBrowse link
G Tpcn1 two pore segment channel 1 decreases expression EXP nefazodone results in decreased expression of TPCN1 mRNA CTD PMID:24136188 NCBI chr12:41,633,399...41,690,200
Ensembl chr12:41,633,398...41,690,200 		JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP nefazodone results in increased expression of TPM1 mRNA CTD PMID:24136188 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468 		JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP nefazodone results in increased expression of TPM3 mRNA CTD PMID:24136188 NCBI chr 2:177,812,534...177,842,661
Ensembl chr 2:177,814,883...177,842,660 		JBrowse link
G Tpm4 tropomyosin 4 decreases expression EXP nefazodone results in decreased expression of TPM4 mRNA CTD PMID:24136188 NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494 		JBrowse link
G Tprg1l tumor protein p63 regulated 1-like increases expression EXP nefazodone results in increased expression of TPRG1L mRNA CTD PMID:24136188 NCBI chr 5:170,004,577...170,007,784
Ensembl chr 5:170,004,577...170,007,983 		JBrowse link
G Tpst1 tyrosylprotein sulfotransferase 1 decreases expression EXP nefazodone results in decreased expression of TPST1 mRNA CTD PMID:24136188 NCBI chr12:32,180,688...32,247,478
Ensembl chr12:32,180,936...32,241,821 		JBrowse link
G Trabd TraB domain containing increases expression EXP nefazodone results in increased expression of TRABD mRNA CTD PMID:24136188 NCBI chr 7:122,034,685...122,045,657
Ensembl chr 7:122,038,553...122,045,657 		JBrowse link
G Trak1 trafficking kinesin protein 1 decreases expression EXP nefazodone results in decreased expression of TRAK1 mRNA CTD PMID:24136188 NCBI chr 8:129,861,967...130,016,870
Ensembl chr 8:129,861,977...130,016,870 		JBrowse link
G Trappc13 trafficking protein particle complex subunit 13 increases expression EXP nefazodone results in increased expression of TRAPPC13 mRNA CTD PMID:24136188 NCBI chr 2:37,004,288...37,035,837
Ensembl chr 2:37,002,976...37,035,820 		JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression EXP nefazodone results in increased expression of TRIB3 mRNA CTD PMID:24136188 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802 		JBrowse link
G Trim26 tripartite motif-containing 26 decreases expression EXP nefazodone results in decreased expression of TRIM26 mRNA CTD PMID:24136188 NCBI chr20:1,711,564...1,736,389
Ensembl chr20:1,715,005...1,736,623 		JBrowse link
G Trim5 tripartite motif-containing 5 decreases expression EXP nefazodone results in decreased expression of TRIM5 mRNA CTD PMID:24136188 NCBI chr 1:168,132,277...168,149,263
Ensembl chr 1:168,132,308...168,141,657 		JBrowse link
G Trmt1 tRNA methyltransferase 1 increases expression EXP nefazodone results in increased expression of TRMT1 mRNA CTD PMID:24136188 NCBI chr19:40,361,583...40,374,971
Ensembl chr19:40,361,583...40,374,622 		JBrowse link
G Tsfm Ts translation elongation factor, mitochondrial increases expression EXP nefazodone results in increased expression of TSFM mRNA CTD PMID:24136188 NCBI chr 7:64,714,330...64,750,106
Ensembl chr 7:64,714,036...64,750,171 		JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression EXP nefazodone results in increased expression of TSKU mRNA CTD PMID:24136188 NCBI chr 1:162,071,459...162,082,972
Ensembl chr 1:162,064,126...162,089,272 		JBrowse link
G Tsnax translin-associated factor X increases expression EXP nefazodone results in increased expression of TSNAX mRNA CTD PMID:24136188 NCBI chr19:69,873,210...69,887,244
Ensembl chr19:69,872,987...69,887,224 		JBrowse link
G Ttc1 tetratricopeptide repeat domain 1 increases expression EXP nefazodone results in increased expression of TTC1 mRNA CTD PMID:24136188 NCBI chr10:28,703,763...28,728,910
Ensembl chr10:28,703,769...28,728,882 		JBrowse link
G Ttc13 tetratricopeptide repeat domain 13 decreases expression EXP nefazodone results in decreased expression of TTC13 mRNA CTD PMID:24136188 NCBI chr19:69,534,989...69,589,590
Ensembl chr19:69,534,989...69,589,563 		JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 decreases expression EXP nefazodone results in decreased expression of TTC3 mRNA CTD PMID:24136188 NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418 		JBrowse link
G Ttyh2 tweety family member 2 decreases expression EXP nefazodone results in decreased expression of TTYH2 mRNA CTD PMID:24136188 NCBI chr10:100,208,129...100,252,505
Ensembl chr10:100,207,860...100,253,521 		JBrowse link
G Ttyh3 tweety family member 3 decreases expression EXP nefazodone results in decreased expression of TTYH3 mRNA CTD PMID:24136188 NCBI chr12:19,110,973...19,139,379
Ensembl chr12:19,110,824...19,139,371 		JBrowse link
G Tuba1c tubulin, alpha 1C increases expression EXP nefazodone results in increased expression of TUBA1C mRNA CTD PMID:24136188 NCBI chr 7:131,636,974...132,078,589
Ensembl chr 7:132,070,536...132,079,311 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP nefazodone results in decreased expression of TUBB2A mRNA CTD PMID:24136188 NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,983,387...31,006,838 		JBrowse link
G Tut7 terminal uridylyl transferase 7 decreases expression EXP nefazodone results in decreased expression of TUT7 mRNA CTD PMID:24136188 NCBI chr17:4,854,553...4,908,758
Ensembl chr17:4,855,936...4,909,070 		JBrowse link
G Txn1 thioredoxin 1 increases expression EXP nefazodone results in increased expression of TXN1 mRNA CTD PMID:24136188 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307 		JBrowse link
G Txnl1 thioredoxin-like 1 increases expression EXP nefazodone results in increased expression of TXNL1 mRNA CTD PMID:24136188 NCBI chr18:59,397,275...59,428,072
Ensembl chr18:59,398,535...59,435,518 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP nefazodone results in increased expression of TXNRD1 mRNA CTD PMID:24136188 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Tysnd1 trypsin like peroxisomal matrix peptidase 1 increases expression EXP nefazodone results in increased expression of TYSND1 mRNA CTD PMID:24136188 NCBI chr20:30,180,878...30,188,239
Ensembl chr20:30,181,090...30,188,236 		JBrowse link
G U2af1 U2 small nuclear RNA auxiliary factor 1 increases expression EXP nefazodone results in increased expression of U2AF1 mRNA CTD PMID:24136188 NCBI chr20:9,744,206...9,755,146
Ensembl chr20:9,744,207...9,755,094 		JBrowse link
G Uba3 ubiquitin-like modifier activating enzyme 3 increases expression EXP nefazodone results in increased expression of UBA3 mRNA CTD PMID:24136188 NCBI chr 4:131,346,219...131,367,378
Ensembl chr 4:131,346,224...131,367,277 		JBrowse link
G Uba5 ubiquitin-like modifier activating enzyme 5 multiple interactions ISO [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with nefazodone] results in increased expression of UBA5 mRNA CTD PMID:33819548 NCBI chr 8:113,544,037...113,559,711
Ensembl chr 8:113,544,037...113,559,711 		JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression EXP nefazodone results in increased expression of UBE2D3 mRNA CTD PMID:24136188 NCBI chr 2:226,543,194...226,571,001
Ensembl chr 2:226,540,531...226,573,144 		JBrowse link
G Ube2f ubiquitin-conjugating enzyme E2F (putative) increases expression EXP nefazodone results in increased expression of UBE2F mRNA CTD PMID:24136188 NCBI chr 9:99,293,506...99,328,690
Ensembl chr 9:99,293,515...99,330,479 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K increases expression EXP nefazodone results in increased expression of UBE2K mRNA CTD PMID:24136188 NCBI chr14:43,011,681...43,077,825
Ensembl chr14:43,011,681...43,072,462 		JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 increases expression EXP nefazodone results in increased expression of UBE2L3 mRNA CTD PMID:24136188 NCBI chr11:97,300,584...97,343,084
Ensembl chr11:97,301,945...97,343,084 		JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M increases expression EXP nefazodone results in increased expression of UBE2M mRNA CTD PMID:24136188 NCBI chr 1:82,734,761...82,738,298
Ensembl chr 1:82,732,231...82,738,613 		JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N increases expression EXP nefazodone results in increased expression of UBE2N mRNA CTD PMID:24136188 NCBI chr 7:32,041,190...32,071,252 JBrowse link
G Ube2q2 ubiquitin conjugating enzyme E2 Q2 increases expression EXP nefazodone results in increased expression of UBE2Q2 mRNA CTD PMID:24136188 NCBI chr 8:64,414,502...64,474,425
Ensembl chr 8:64,414,301...64,474,418 		JBrowse link
G Ube2v2 ubiquitin conjugating enzyme E2 V2 increases expression EXP nefazodone results in increased expression of UBE2V2 mRNA CTD PMID:24136188 NCBI chr11:98,808,681...98,842,583
Ensembl chr11:98,807,538...98,843,211 		JBrowse link
G Ube2z ubiquitin-conjugating enzyme E2Z increases expression EXP nefazodone results in increased expression of UBE2Z mRNA CTD PMID:24136188 NCBI chr10:81,494,522...81,513,641
Ensembl chr10:81,494,523...81,513,641 		JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression EXP nefazodone results in increased expression of UBE3A mRNA CTD PMID:24136188 NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:119,206,148...119,297,097 		JBrowse link
G Ube3c ubiquitin protein ligase E3C increases expression EXP nefazodone results in increased expression of UBE3C mRNA CTD PMID:24136188 NCBI chr 4:6,323,831...6,425,085
Ensembl chr 4:6,323,831...6,424,845 		JBrowse link
G Ube4a ubiquitination factor E4A increases expression EXP nefazodone results in increased expression of UBE4A mRNA CTD PMID:24136188 NCBI chr 8:54,132,799...54,174,921
Ensembl chr 8:54,132,801...54,174,835 		JBrowse link
G Ube4b ubiquitination factor E4B increases expression EXP nefazodone results in increased expression of UBE4B mRNA CTD PMID:24136188 NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:165,049,897...165,153,572 		JBrowse link
G Ubfd1 ubiquitin family domain containing 1 increases expression EXP nefazodone results in increased expression of UBFD1 mRNA CTD PMID:24136188 NCBI chr 1:186,057,267...186,068,832
Ensembl chr 1:186,057,123...186,066,103 		JBrowse link
G Ubl3 ubiquitin-like 3 increases expression EXP nefazodone results in increased expression of UBL3 mRNA CTD PMID:24136188 NCBI chr12:11,509,912...11,554,548
Ensembl chr12:11,509,848...11,554,547 		JBrowse link
G Ubqln1 ubiquilin 1 increases expression EXP nefazodone results in increased expression of UBQLN1 mRNA CTD PMID:24136188 NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,444,124...6,482,499 		JBrowse link
G Ubqln2 ubiquilin 2 increases expression EXP nefazodone results in increased expression of UBQLN2 mRNA CTD PMID:24136188 NCBI chr  X:21,228,809...21,232,228
Ensembl chr  X:21,229,197...21,232,268 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 increases expression EXP nefazodone results in increased expression of UBR4 mRNA CTD PMID:24136188 NCBI chr 5:156,919,029...157,027,127
Ensembl chr 5:156,919,085...157,027,127 		JBrowse link
G Ubxn1 UBX domain protein 1 increases expression EXP nefazodone results in increased expression of UBXN1 mRNA CTD PMID:24136188 NCBI chr 1:215,194,418...215,198,343
Ensembl chr 1:215,174,216...215,198,343 		JBrowse link
G Ubxn4 UBX domain protein 4 increases expression EXP nefazodone results in increased expression of UBXN4 mRNA CTD PMID:24136188 NCBI chr13:42,292,346...42,324,928
Ensembl chr13:42,292,528...42,326,143 		JBrowse link
G Uchl3-ps1 ubiquitin C-terminal hydrolase L3, pseudogene 1 increases expression EXP nefazodone results in increased expression of UCHL3-PS1 mRNA CTD PMID:24136188 NCBI chr 3:182,275,286...182,276,167 JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 increases expression EXP nefazodone results in increased expression of UCHL5 mRNA CTD PMID:24136188 NCBI chr13:58,070,947...58,106,825
Ensembl chr13:58,042,029...58,107,441 		JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 increases expression EXP nefazodone results in increased expression of UFD1 mRNA CTD PMID:24136188 NCBI chr11:95,665,971...95,689,423
Ensembl chr11:95,665,972...95,689,434 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 increases expression EXP nefazodone results in increased expression of UFL1 mRNA CTD PMID:24136188 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:43,758,098...43,791,682 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase increases expression EXP nefazodone results in increased expression of UGDH mRNA CTD PMID:24136188 NCBI chr14:43,202,480...43,226,002
Ensembl chr14:43,202,356...43,226,629 		JBrowse link
G Uggt1 UDP-glucose glycoprotein glucosyltransferase 1 increases expression EXP nefazodone results in increased expression of UGGT1 mRNA CTD PMID:24136188 NCBI chr 9:45,851,127...45,964,454
Ensembl chr 9:45,854,985...45,964,455 		JBrowse link
G Ugt1a6a UDP glucuronosyltransferase family 1 member A6a increases expression EXP nefazodone results in increased expression of UGT1A6 mRNA CTD PMID:24136188 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP nefazodone results in increased expression of UGT2B17 mRNA CTD PMID:24136188 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331 		JBrowse link
G Ulk2 unc-51 like autophagy activating kinase 2 decreases expression EXP nefazodone results in decreased expression of ULK2 mRNA CTD PMID:24136188 NCBI chr10:46,951,038...47,029,844
Ensembl chr10:46,951,038...47,029,844 		JBrowse link
G Umps uridine monophosphate synthetase increases expression EXP nefazodone results in increased expression of UMPS mRNA CTD PMID:24136188 NCBI chr11:80,311,269...80,321,678
Ensembl chr11:80,311,214...80,327,828 		JBrowse link
G Ung uracil-DNA glycosylase increases expression EXP nefazodone results in increased expression of UNG mRNA CTD PMID:24136188 NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257 		JBrowse link
G Unkl unk like zinc finger increases expression EXP nefazodone results in increased expression of UNKL mRNA CTD PMID:24136188 NCBI chr10:14,710,627...14,756,725
Ensembl chr10:14,710,563...14,756,724 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 increases expression EXP nefazodone results in increased expression of UQCRC1 mRNA CTD PMID:24136188 NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964 		JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 increases expression EXP nefazodone results in increased expression of UQCRC2 mRNA CTD PMID:24136188 NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone increases expression EXP nefazodone results in increased expression of URI1 mRNA CTD PMID:24136188 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:99,783,158...99,853,906 		JBrowse link
G Use1 unconventional SNARE in the ER 1 increases expression EXP nefazodone results in increased expression of USE1 mRNA CTD PMID:24136188 NCBI chr16:18,069,118...18,075,816
Ensembl chr16:18,070,793...18,075,814 		JBrowse link
G Usp10 ubiquitin specific peptidase 10 increases expression EXP nefazodone results in increased expression of USP10 mRNA CTD PMID:24136188 NCBI chr19:64,881,255...64,923,522
Ensembl chr19:64,881,315...64,923,519 		JBrowse link
G Usp14 ubiquitin specific peptidase 14 increases expression EXP nefazodone results in increased expression of USP14 mRNA CTD PMID:24136188 NCBI chr18:1,292,745...1,330,867
Ensembl chr18:1,292,745...1,330,336 		JBrowse link
G Usp3 ubiquitin specific peptidase 3 increases expression EXP nefazodone results in increased expression of USP3 mRNA CTD PMID:24136188 NCBI chr 8:75,973,278...76,049,151
Ensembl chr 8:75,974,615...76,049,153 		JBrowse link
G Usp39 ubiquitin specific peptidase 39 increases expression EXP nefazodone results in increased expression of USP39 mRNA CTD PMID:24136188 NCBI chr 4:105,932,140...105,964,551
Ensembl chr 4:105,932,140...105,964,551 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 increases expression EXP nefazodone results in increased expression of USP47 mRNA CTD PMID:24136188 NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:175,586,723...175,669,904 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 increases expression EXP nefazodone results in increased expression of USP5 mRNA CTD PMID:24136188 NCBI chr 4:159,305,927...159,321,345
Ensembl chr 4:159,305,938...159,320,956 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 increases expression EXP nefazodone results in increased expression of USP7 mRNA CTD PMID:24136188 NCBI chr10:7,335,508...7,432,018
Ensembl chr10:7,367,604...7,432,013 		JBrowse link
G Ust4r integral membrane transport protein UST4r increases expression EXP nefazodone results in increased expression of UST4R mRNA CTD PMID:24136188 NCBI chr 1:214,501,347...214,571,852
Ensembl chr 1:214,501,347...214,571,832 		JBrowse link
G Ust5r integral membrane transport protein UST5r decreases expression EXP nefazodone results in decreased expression of UST5R mRNA CTD PMID:24136188 NCBI chr 1:214,640,172...214,716,024
Ensembl chr 1:214,640,172...214,715,861 		JBrowse link
G Vat1 vesicle amine transport 1 increases expression EXP nefazodone results in increased expression of VAT1 mRNA CTD PMID:24136188 NCBI chr10:86,889,793...86,897,411
Ensembl chr10:86,889,793...86,897,411 		JBrowse link
G Vcp valosin-containing protein increases expression EXP nefazodone results in increased expression of VCP mRNA CTD PMID:24136188 NCBI chr 5:62,005,984...62,025,387
Ensembl chr 5:62,005,985...62,025,387 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression EXP nefazodone results in increased expression of VDAC1 mRNA CTD PMID:24136188 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541 		JBrowse link
G Vdac3 voltage-dependent anion channel 3 increases expression EXP nefazodone results in increased expression of VDAC3 mRNA CTD PMID:24136188 NCBI chr16:76,137,489...76,153,933
Ensembl chr16:76,137,504...76,155,304 		JBrowse link
G Vim vimentin decreases expression EXP nefazodone results in decreased expression of VIM mRNA CTD PMID:24136188 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:81,568,272...81,585,746 		JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 decreases expression EXP nefazodone results in decreased expression of VKORC1 mRNA CTD PMID:24136188 NCBI chr 1:191,932,969...191,935,490 JBrowse link
G Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 increases expression EXP nefazodone results in increased expression of VKORC1L1 mRNA CTD PMID:24136188 NCBI chr12:32,354,078...32,404,327 JBrowse link
G Vnn1 vanin 1 increases expression EXP nefazodone results in increased expression of VNN1 mRNA CTD PMID:24136188 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629 		JBrowse link
G Vps26a VPS26 retromer complex component A increases expression EXP nefazodone results in increased expression of VPS26A mRNA CTD PMID:24136188 NCBI chr20:30,947,018...30,976,964
Ensembl chr20:30,947,023...30,976,827 		JBrowse link
G Vps29 VPS29 retromer complex component increases expression EXP nefazodone results in increased expression of VPS29 mRNA CTD PMID:24136188 NCBI chr12:39,869,688...39,878,732
Ensembl chr12:39,869,688...39,878,848 		JBrowse link
G Vps35 VPS35 retromer complex component increases expression EXP nefazodone results in increased expression of VPS35 mRNA CTD PMID:24136188 NCBI chr19:37,938,989...37,974,887
Ensembl chr19:37,938,720...37,974,886 		JBrowse link
G Vwa8 von Willebrand factor A domain containing 8 increases expression EXP nefazodone results in increased expression of VWA8 mRNA CTD PMID:24136188 NCBI chr15:60,661,764...60,985,971
Ensembl chr15:60,661,877...60,985,971 		JBrowse link
G Wapl WAPL cohesin release factor increases expression EXP nefazodone results in increased expression of WAPL mRNA CTD PMID:24136188 NCBI chr16:10,011,741...10,081,472
Ensembl chr16:10,012,110...10,081,472 		JBrowse link
G Wasl WASP like actin nucleation promoting factor increases expression EXP nefazodone results in increased expression of WASL mRNA CTD PMID:24136188 NCBI chr 4:54,049,081...54,097,653
Ensembl chr 4:54,049,082...54,097,570 		JBrowse link
G Wdr36 WD repeat domain 36 increases expression EXP nefazodone results in increased expression of WDR36 mRNA CTD PMID:24136188 NCBI chr18:24,747,812...24,783,704
Ensembl chr18:24,747,832...24,783,110 		JBrowse link
G Wdr45 WD repeat domain 45 increases expression EXP nefazodone results in increased expression of WDR45 mRNA CTD PMID:24136188 NCBI chr  X:17,448,195...17,454,117
Ensembl chr  X:17,448,207...17,454,117 		JBrowse link
G Wdr77 WD repeat domain 77 increases expression EXP nefazodone results in increased expression of WDR77 mRNA CTD PMID:24136188 NCBI chr 2:196,123,882...196,133,853
Ensembl chr 2:196,123,848...196,134,567 		JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression EXP nefazodone results in decreased expression of WSB1 mRNA CTD PMID:24136188 NCBI chr10:64,700,752...64,717,038
Ensembl chr10:64,700,762...64,716,832 		JBrowse link
G Wwc3 WWC family member 3 increases expression EXP nefazodone results in increased expression of WWC3 mRNA CTD PMID:24136188 NCBI chr  X:27,146,018...27,263,446
Ensembl chr  X:27,145,812...27,263,446 		JBrowse link
G Xbp1 X-box binding protein 1 increases splicing ISO nefazodone results in increased splicing of XBP1 mRNA CTD PMID:27613715 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Xdh xanthine dehydrogenase decreases expression EXP nefazodone results in decreased expression of XDH mRNA CTD PMID:24136188 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression EXP nefazodone results in decreased expression of XPC mRNA CTD PMID:24136188 NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305 		JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 decreases expression EXP nefazodone results in decreased expression of XPNPEP2 mRNA CTD PMID:24136188 NCBI chr  X:132,165,696...132,194,937
Ensembl chr  X:132,165,701...132,195,126 		JBrowse link
G Xpo1 exportin 1 increases expression EXP nefazodone results in increased expression of XPO1 mRNA CTD PMID:24136188 NCBI chr14:101,434,450...101,476,705
Ensembl chr14:101,434,517...101,476,714 		JBrowse link
G Xpot exportin for tRNA increases expression EXP nefazodone results in increased expression of XPOT mRNA CTD PMID:24136188 NCBI chr 7:58,997,025...59,037,506
Ensembl chr 7:58,997,025...59,037,502 		JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 increases expression EXP nefazodone results in increased expression of YARS1 mRNA CTD PMID:24136188 NCBI chr 5:146,820,163...146,848,377
Ensembl chr 5:146,819,358...146,848,377 		JBrowse link
G Yif1a Yip1 interacting factor homolog A, membrane trafficking protein increases expression EXP nefazodone results in increased expression of YIF1A mRNA CTD PMID:24136188 NCBI chr 1:211,823,921...211,828,437
Ensembl chr 1:211,824,273...211,828,802 		JBrowse link
G Yipf1 Yip1 domain family, member 1 decreases expression EXP nefazodone results in decreased expression of YIPF1 mRNA CTD PMID:24136188 NCBI chr 5:127,340,962...127,376,270
Ensembl chr 5:127,340,953...127,376,538 		JBrowse link
G Yipf4 Yip1 domain family, member 4 increases expression EXP nefazodone results in increased expression of YIPF4 mRNA CTD PMID:24136188 NCBI chr 6:26,702,647...26,714,066
Ensembl chr 6:26,682,488...26,714,066 		JBrowse link
G Ypel3 yippee-like 3 decreases expression EXP nefazodone results in decreased expression of YPEL3 mRNA CTD PMID:24136188 NCBI chr 1:190,814,920...190,818,248
Ensembl chr 1:190,814,512...190,818,251 		JBrowse link
G Ypel5 yippee-like 5 increases expression EXP nefazodone results in increased expression of YPEL5 mRNA CTD PMID:24136188 NCBI chr 6:28,408,079...28,423,536
Ensembl chr 6:28,408,080...28,412,385 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta increases expression EXP nefazodone results in increased expression of YWHAB mRNA CTD PMID:24136188 NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma increases expression EXP nefazodone results in increased expression of YWHAG mRNA CTD PMID:24136188 NCBI chr12:26,381,106...26,409,466
Ensembl chr12:26,380,816...26,409,465 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression EXP nefazodone results in increased expression of YWHAQ mRNA CTD PMID:24136188 NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875 		JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta increases expression EXP nefazodone results in increased expression of YWHAZ mRNA CTD PMID:24136188 NCBI chr 7:69,826,404...69,848,702
Ensembl chr 7:69,826,404...69,849,007 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 decreases expression EXP nefazodone results in decreased expression of ZBTB20 mRNA CTD PMID:24136188 NCBI chr11:70,558,010...71,297,039
Ensembl chr11:70,580,930...70,736,237 		JBrowse link
G Zdhhc7 zinc finger DHHC-type palmitoyltransferase 7 increases expression EXP nefazodone results in increased expression of ZDHHC7 mRNA CTD PMID:24136188 NCBI chr19:65,048,140...65,065,286
Ensembl chr19:65,037,310...65,065,286 		JBrowse link
G Zfand2a zinc finger AN1-type containing 2A increases expression EXP nefazodone results in increased expression of ZFAND2A mRNA CTD PMID:24136188 NCBI chr12:20,275,435...20,286,513
Ensembl chr12:20,275,450...20,286,513 		JBrowse link
G Zfp110 zinc finger protein 110 decreases expression EXP nefazodone results in decreased expression of ZFP110 mRNA CTD PMID:24136188 NCBI chr 1:82,509,563...82,533,294
Ensembl chr 1:82,517,769...82,533,292 		JBrowse link
G Zfp260 zinc finger protein 260 decreases expression EXP nefazodone results in decreased expression of ZFP260 mRNA CTD PMID:24136188 NCBI chr 1:94,469,861...94,477,377
Ensembl chr 1:94,460,733...94,478,217 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 decreases expression EXP nefazodone results in decreased expression of ZFP36L1 mRNA CTD PMID:24136188 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979 		JBrowse link
G Zfp386 zinc finger protein 386 (Kruppel-like) decreases expression EXP nefazodone results in decreased expression of ZFP386 mRNA CTD PMID:24136188 NCBI chr 6:143,109,563...143,124,266
Ensembl chr 6:143,109,610...143,127,027 		JBrowse link
G Zfp598 zinc finger protein 598 increases expression EXP nefazodone results in increased expression of ZFP598 mRNA CTD PMID:24136188 NCBI chr10:14,198,763...14,210,773
Ensembl chr10:14,185,611...14,210,772 		JBrowse link
G Zfp706 zinc finger protein 706 increases expression EXP nefazodone results in increased expression of ZFP706 mRNA CTD PMID:24136188 NCBI chr 7:70,050,960...70,059,588
Ensembl chr 7:70,052,534...70,059,159 		JBrowse link
G Zfyve21 zinc finger FYVE-type containing 21 decreases expression EXP nefazodone results in decreased expression of ZFYVE21 mRNA CTD PMID:24136188 NCBI chr 6:136,695,132...136,715,601
Ensembl chr 6:136,694,908...136,715,601 		JBrowse link
G Zkscan3 zinc finger with KRAB and SCAN domains 3 decreases expression EXP nefazodone results in decreased expression of ZKSCAN3 mRNA CTD PMID:24136188 NCBI chr17:47,912,816...47,928,553
Ensembl chr17:47,912,912...47,928,551 		JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 decreases expression EXP nefazodone results in decreased expression of ZMIZ2 mRNA CTD PMID:24136188 NCBI chr14:85,465,323...85,481,860
Ensembl chr14:85,465,373...85,481,860 		JBrowse link
G Zpr1 ZPR1 zinc finger increases expression EXP nefazodone results in increased expression of ZPR1 mRNA CTD PMID:24136188 NCBI chr 8:55,461,839...55,471,413
Ensembl chr 8:55,461,839...55,471,413 		JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression EXP nefazodone results in increased expression of ZWINT mRNA CTD PMID:24136188 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203 		JBrowse link
oxymetazoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions
affects binding 		ISO
EXP 		[Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; Oxymetazoline binds to and results in increased activity of ADRA1A protein; Oxymetazoline inhibits the reaction [ADRA1A protein binds to Prazosin]; Oxymetazoline inhibits the reaction [Prazosin binds to ADRA1A protein]
Oxymetazoline binds to ADRA1A protein 		CTD PMID:8196478 PMID:15872040 PMID:20030735 PMID:21544540 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions
affects binding 		ISO Oxymetazoline inhibits the reaction [ADRA1B protein binds to Prazosin]
Oxymetazoline binds to ADRA1B protein 		CTD PMID:20030735 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions
affects binding 		ISO Oxymetazoline inhibits the reaction [ADRA1D protein binds to Prazosin]
Oxymetazoline binds to ADRA1D protein 		CTD PMID:15493479 PMID:20030735 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions
affects binding 		ISO Oxymetazoline inhibits the reaction [ADRA2A protein binds to 2-methoxyidazoxan]
Oxymetazoline binds to ADRA2A protein 		CTD PMID:20030735 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; Oxymetazoline binds to and results in increased activity of ADRA2B protein; Oxymetazoline inhibits the reaction [ADRA2B protein binds to 2-methoxyidazoxan] CTD PMID:20030735 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adra2c adrenoceptor alpha 2C affects binding
multiple interactions 		ISO Oxymetazoline binds to ADRA2C protein
Oxymetazoline inhibits the reaction [ADRA2C protein binds to 2-methoxyidazoxan] 		CTD PMID:20030735 NCBI chr14:79,695,514...79,697,476
Ensembl chr14:79,694,995...79,706,656 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [CYP2C19 protein co-treated with NADP] results in increased metabolism of Oxymetazoline CTD PMID:21177487 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Oxymetazoline inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
paliperidone palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
multiple interactions
increases export
increases transport
affects response to substance
decreases activity 		ISO
EXP 		ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate; ABCB1 protein affects the abundance of Paliperidone Palmitate
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Paliperidone Palmitate]
ABCB1A protein results in increased transport of Paliperidone Palmitate
ABCB1A protein affects the susceptibility to Paliperidone Palmitate
Paliperidone Palmitate results in decreased activity of ABCB1 protein
Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]
ABCB1 protein results in increased transport of Paliperidone Palmitate 		CTD PMID:15502009 PMID:16118767 PMID:16810505 PMID:16936711 PMID:17541883 More... NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Paliperidone Palmitate CTD PMID:15502009 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Paliperidone Palmitate results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Paliperidone Palmitate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Paliperidone Palmitate results in increased expression of BDNF mRNA CTD PMID:21220416 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects abundance ISO CYP2D6 gene polymorphism affects the abundance of Paliperidone Palmitate; CYP2D6 protein affects the abundance of Paliperidone Palmitate CTD PMID:10639689 PMID:15089809 PMID:17541883 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding 		ISO
EXP 		Paliperidone Palmitate binds to and results in decreased activity of DRD2 protein
Paliperidone Palmitate binds to DRD2 protein 		CTD PMID:19713555 PMID:22437487 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:58,605,403...58,669,339 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions 		EXP Paliperidone Palmitate results in increased expression of FADS2 mRNA
[Paliperidone Palmitate results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, Unsaturated 		CTD PMID:21458237 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions 		ISO
EXP 		Paliperidone Palmitate binds to HTR2A protein
Paliperidone Palmitate binds to and results in decreased activity of HTR2A protein 		CTD PMID:7520908 PMID:19713555 PMID:22437487 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 PMID:20827463 NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:243,049,081...243,173,230 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Paliperidone Palmitate results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Paliperidone Palmitate results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il24 interleukin 24 increases expression ISO Paliperidone Palmitate results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Paliperidone Palmitate results in decreased activity of KCNH2 protein CTD PMID:21394035 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Prl prolactin increases expression ISO Paliperidone Palmitate results in increased expression of PRL protein CTD PMID:17460786 PMID:19825908 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217 		JBrowse link
phentolamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Phentolamine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:26,106,895...26,164,440 JBrowse link
G Adra1a adrenoceptor alpha 1A affects binding
multiple interactions 		ISO Phentolamine binds to ADRA1A protein
Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium] 		CTD PMID:15306222 PMID:21544540 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B affects binding
multiple interactions 		ISO Phentolamine binds to ADRA1B protein
Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] 		CTD PMID:15306222 NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects binding
multiple interactions 		ISO Phentolamine binds to ADRA1D protein
Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] 		CTD PMID:15306222 PMID:15493479 NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions EXP Phentolamine binds to and results in decreased activity of ADRA2A protein CTD PMID:8397342 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity 		ISO Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP3 protein] CTD PMID:22700542 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions 		ISO Phentolamine results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [Phentolamine results in increased activity of CASP7 protein] 		CTD PMID:22700542 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Ereg epiregulin decreases expression ISO Phentolamine results in decreased expression of EREG mRNA CTD PMID:32816093 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO Phentolamine inhibits the reaction [Ethylene Dibromide results in increased activity of GGT1 protein] CTD PMID:12628311 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050 		JBrowse link
G Il24 interleukin 24 decreases expression ISO Phentolamine results in decreased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity 		ISO Phentolamine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Phentolamine results in decreased activity of KCNH2 protein 		CTD PMID:19583963 PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein] CTD PMID:15306222 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein] CTD PMID:15306222 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO Phentolamine results in decreased expression of MET mRNA CTD PMID:32816093 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Phentolamine inhibits the reaction [POMC results in increased uptake of Magnesium] CTD PMID:191614 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Pygl glycogen phosphorylase L multiple interactions EXP Phentolamine inhibits the reaction [Neostigmine results in increased activity of PYGL protein modified form] CTD PMID:1350317 NCBI chr 6:94,433,558...94,476,219
Ensembl chr 6:94,426,346...94,476,269 		JBrowse link
G Ren renin increases activity ISO Phentolamine results in increased activity of REN protein CTD PMID:6173514 NCBI chr13:47,348,312...47,359,539
Ensembl chr13:47,348,143...47,359,543 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Phentolamine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO
EXP 		Phentolamine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:12411423 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Phentolamine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,533,580...46,590,128
Ensembl chr10:46,533,583...46,587,096 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Phentolamine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,490,262...46,532,954
Ensembl chr10:46,489,831...46,533,425 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO
EXP 		SULT1A1 protein results in increased sulfation of Phentolamine CTD PMID:11181495 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Phentolamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:11752888 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
phenylephrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression EXP Phenylephrine results in decreased expression of ABCC9 mRNA CTD PMID:18158353 NCBI chr 4:177,262,848...177,386,837
Ensembl chr 4:177,262,848...177,386,348 		JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase increases expression EXP Phenylephrine results in increased expression of ABHD2 mRNA CTD PMID:18158353 NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase multiple interactions
increases phosphorylation
affects response to substance 		EXP ABL1 protein affects the reaction [Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein]]; ABL1 protein affects the reaction [Phenylephrine promotes the reaction [CRK protein binds to WASL protein]]; ABL1 protein affects the reaction [Phenylephrine results in increased phosphorylation of BCAR1 protein]
Phenylephrine results in increased phosphorylation of ABL1 protein
ABL1 protein affects the susceptibility to Phenylephrine 		CTD PMID:17615370 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:35,377,391...35,480,846 		JBrowse link
G Abtb3 ankyrin repeat and BTB domain containing 3 decreases expression EXP Phenylephrine results in decreased expression of ABTB3 mRNA CTD PMID:18158353 NCBI chr 7:19,922,883...20,199,740
Ensembl chr 7:19,923,814...20,198,110 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions
decreases expression 		EXP AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of ACADM mRNA]; dorsomorphin promotes the reaction [Phenylephrine results in decreased expression of ACADM mRNA] CTD PMID:19699196 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP Phenylephrine results in increased expression of ACAT2 mRNA CTD PMID:18158353 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Ace angiotensin I converting enzyme affects response to substance ISO ACE protein affects the susceptibility to Phenylephrine CTD PMID:18431347 NCBI chr10:91,410,129...91,430,246
Ensembl chr10:91,409,819...91,430,942 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP Phenylephrine results in increased expression of ACOT2 mRNA CTD PMID:18158353 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:109,342,646...109,350,502 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions
increases expression 		ISO
EXP 		[Phenylephrine co-treated with ADRA1B protein] results in increased expression of ACTA1 protein; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA; [Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of ACTA1 mRNA; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]
MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; RGS2 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; S100A6 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; S100B protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; TGFB1I1 protein promotes the reaction [Phenylephrine results in increased expression of ACTA1 mRNA] 		CTD PMID:10642269 PMID:10710348 PMID:11230109 PMID:11499749 PMID:11513749 More... NCBI chr19:68,781,168...68,784,194
Ensembl chr19:68,781,168...68,786,178 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression 		EXP MYOCD protein affects the reaction [Phenylephrine results in increased expression of ACTA2 mRNA] CTD PMID:16556869 PMID:18158353 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503 		JBrowse link
G Actr3 actin related protein 3 increases expression EXP Phenylephrine results in increased expression of ACTR3 mRNA CTD PMID:18158353 NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions EXP ADAM17 protein affects the reaction [Phenylephrine results in increased cleavage of and results in increased secretion of EGF protein]; ADAM17 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; ADAM17 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] CTD PMID:16760267 NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:46,601,583...46,649,344 		JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance ISO ADCY5 protein results in increased susceptibility to Phenylephrine CTD PMID:12869393 NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343 		JBrowse link
G Adhfe1 alcohol dehydrogenase, iron containing, 1 decreases expression EXP Phenylephrine results in decreased expression of ADHFE1 mRNA CTD PMID:18158353 NCBI chr 5:14,488,784...14,515,405
Ensembl chr 5:14,488,788...14,515,835 		JBrowse link
G Adm adrenomedullin multiple interactions
increases expression
decreases secretion
decreases expression
decreases response to substance 		EXP
ISO 		[Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM mRNA; [Phenylephrine co-treated with Isoproterenol] results in increased expression of ADM protein; ADM protein inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; ADM protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Phenylephrine results in increased expression of ADM mRNA; Phenylephrine results in increased expression of ADM protein
Phenylephrine results in decreased secretion of ADM protein
Phenylephrine results in decreased expression of ADM mRNA
ADM protein results in decreased susceptibility to Phenylephrine 		CTD PMID:11470465 PMID:15370692 PMID:17250927 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions
increases expression 		EXP 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]]; 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein]]; ADORA1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein]; N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]; N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein]
Phenylephrine results in increased expression of ADORA1 mRNA; Phenylephrine results in increased expression of ADORA1 protein 		CTD PMID:19966059 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:48,213,273...48,247,190 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions
increases expression 		EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]]; ADORA2A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]
Phenylephrine results in increased expression of ADORA2A mRNA; Phenylephrine results in increased expression of ADORA2A protein 		CTD PMID:19966059 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802 		JBrowse link
G Adora3 adenosine A3 receptor multiple interactions
increases expression 		EXP 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]]; ADORA3 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]; alpha,beta-methyleneadenosine 5'-diphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 mRNA]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of ADORA3 protein]
Phenylephrine results in increased expression of ADORA3 mRNA; Phenylephrine results in increased expression of ADORA3 protein 		CTD PMID:19966059 NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:196,077,042...196,080,686 		JBrowse link
G Adprhl1 ADP-ribosylhydrolase like 1 increases expression EXP Phenylephrine results in increased expression of ADPRHL1 mRNA CTD PMID:18158353 NCBI chr16:82,985,355...83,017,240 JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
increases activity
affects activity
increases response to substance
affects binding
affects response to substance 		ISO
EXP 		5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [Colforsin co-treated with 1-Methyl-3-isobutylxanthine] affects the reaction [[Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium]; [KCND3 protein co-treated with ADRA1A protein] affects the susceptibility to Phenylephrine; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the abundance of Phosphatidylinositol 4,5-Diphosphate; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which affects the transport of Potassium; [Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein; [Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein; [Phenylephrine results in increased activity of ADRA1A protein] which affects the transport of Potassium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; KT 5720 inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phenylephrine binds to and results in increased activity of ADRA1A protein; Phenylephrine results in decreased activity of [KCND3 protein alternative form co-treated with ADRA1A protein]; Prazosin inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]; Ro 32-0432 inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in decreased transport of Potassium]
8-Hydroxy-2-(di-n-propylamino)tetralin promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein]; [Phenylephrine affects the activity of ADRA1A protein] which affects the transport of Potassium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased transport of Glucose; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]; Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]; GR 127935 promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein]; Granisetron promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein]; Lisuride promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein]; Methysergide promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein]; Phenylephrine binds to and results in increased activity of ADRA1A protein
ADRA1A protein results in increased susceptibility to Phenylephrine
Phenylephrine binds to ADRA1A protein
ADRA1A protein affects the susceptibility to Phenylephrine 		CTD PMID:8183249 PMID:11709419 PMID:12935885 PMID:15306222 PMID:15365637 More... NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Adra1b adrenoceptor alpha 1B affects response to substance
multiple interactions
increases activity
decreases expression
increases response to substance 		ISO
EXP 		ADRA1B protein affects the susceptibility to Phenylephrine
[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein; [Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]
Phenylephrine results in decreased expression of ADRA1B mRNA; Phenylephrine results in decreased expression of ADRA1B protein
ADRA1B protein results in increased susceptibility to Phenylephrine
4-Aminopyridine inhibits the reaction [ADRA1B protein results in increased susceptibility to Phenylephrine]; ADRA1B protein affects the reaction [Phenylephrine results in decreased activity of TGM2 protein]; chlorethylclonidine inhibits the reaction [ADRA1B protein results in increased susceptibility to Phenylephrine]; Estradiol promotes the reaction [ADRA1B protein results in increased susceptibility to Phenylephrine]
[Phenylephrine co-treated with ADRA1B protein] results in decreased expression of ATP2A2 protein; [Phenylephrine co-treated with ADRA1B protein] results in decreased expression of NPY protein; [Phenylephrine co-treated with ADRA1B protein] results in increased expression of ACTA1 protein; [Phenylephrine co-treated with ADRA1B protein] results in increased expression of GRK2 protein; [Phenylephrine co-treated with ADRA1B protein] results in increased expression of NPPA protein 		CTD PMID:10801782 PMID:11499749 PMID:11693201 PMID:15306222 PMID:16498073 More... NCBI chr10:28,756,461...28,874,831
Ensembl chr10:28,756,461...28,814,347 		JBrowse link
G Adra1d adrenoceptor alpha 1D affects response to substance
increases activity
affects binding
multiple interactions
increases response to substance 		ISO
EXP 		ADRA1D protein affects the susceptibility to Phenylephrine
Phenylephrine results in increased activity of ADRA1D protein
Phenylephrine binds to ADRA1D protein
[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein; [Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]
BMY 7378 inhibits the reaction [ADRA1D protein results in increased susceptibility to Phenylephrine]; Phenylephrine binds to and results in increased activity of ADRA1D protein
ADRA1D affects the susceptibility to Phenylephrine 		CTD PMID:8183249 PMID:11901185 PMID:15306222 PMID:15493479 PMID:16371063 More... NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:139,246,323...139,262,331 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]; Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Brimonidine Tartrate binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]] CTD PMID:10742289 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871 		JBrowse link
G Adra2b adrenoceptor alpha 2B affects response to substance
multiple interactions 		ISO ADRA2B protein affects the susceptibility to Phenylephrine
ADRA2B protein affects the susceptibility to [Phenylephrine co-treated with Acetylcholine] 		CTD PMID:16815979 NCBI chr 3:135,038,481...135,042,527
Ensembl chr 3:135,038,474...135,042,525 		JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions EXP [Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine; [Salmeterol Xinafoate binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine; [Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine; CGP 20712A inhibits the reaction [[Fenoterol binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; CGP 20712A inhibits the reaction [[Salmeterol Xinafoate binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; CGP 20712A inhibits the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; Pertussis Toxin promotes the reaction [[Salmeterol Xinafoate binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine]; Pertussis Toxin promotes the reaction [[Terbutaline binds to and results in increased activity of ADRB2 protein] which results in decreased susceptibility to Phenylephrine] CTD PMID:16474418 NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases response to substance 		ISO amibegron inhibits the reaction [ADRB3 protein results in increased susceptibility to Phenylephrine] CTD PMID:16022967 NCBI chr16:71,544,603...71,547,410
Ensembl chr16:71,542,567...71,547,420 		JBrowse link
G Agt angiotensinogen affects response to substance
increases response to substance
multiple interactions
increases expression 		EXP
ISO 		AGT protein affects the susceptibility to Phenylephrine
AGT protein modified form results in increased susceptibility to Phenylephrine
AGT protein modified form promotes the reaction [Phenylephrine results in increased abundance of Inositol Phosphates]; carvedilol inhibits the reaction [AGT protein modified form promotes the reaction [Phenylephrine results in increased abundance of Inositol Phosphates]]; carvedilol inhibits the reaction [AGT protein modified form results in increased susceptibility to Phenylephrine]; irbesartan inhibits the reaction [AGT protein modified form results in increased susceptibility to Phenylephrine]
Phenylephrine results in increased expression of AGT mRNA; Phenylephrine results in increased expression of AGT protein
[Phenylephrine results in increased expression of AGT protein] which results in increased activity of MMP2 protein; AGT protein promotes the reaction [Phenylephrine results in increased expression of FOS mRNA]; Losartan inhibits the reaction [[Phenylephrine results in increased expression of AGT protein] which results in increased activity of MMP2 protein]; PRKCZ protein affects the reaction [Phenylephrine results in increased expression of AGT mRNA] 		CTD PMID:2298476 PMID:7900855 PMID:16251426 PMID:16794485 PMID:27094369 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 multiple interactions
affects response to substance 		EXP
ISO 		[CGP 42112A binds to and results in increased activity of AGTR2 protein] which affects the susceptibility to Phenylephrine; [PD 123319 binds to and results in decreased activity of AGTR2 protein] which affects the susceptibility to Phenylephrine
AGTR2 protein affects the susceptibility to Phenylephrine 		CTD PMID:11714657 PMID:19151255 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:116,913,656...116,918,745 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Phenylephrine results in increased expression of AIFM1 protein CTD PMID:31605733 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237 		JBrowse link
G Ak4 adenylate kinase 4 increases expression EXP Phenylephrine results in increased expression of AK4 mRNA CTD PMID:18158353 NCBI chr 5:121,154,565...121,214,403
Ensembl chr 5:121,154,572...121,214,401 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases phosphorylation
affects phosphorylation 		ISO
EXP 		Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein]
GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein]
Phenylephrine affects the phosphorylation of AKT1 protein 		CTD PMID:10679475 PMID:18084315 PMID:28759639 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression EXP Phenylephrine results in increased expression of ALDH18A1 mRNA CTD PMID:18158353 NCBI chr 1:249,325,082...249,357,383
Ensembl chr 1:249,325,082...249,357,383 		JBrowse link
G Angpt1 angiopoietin 1 multiple interactions
increases expression 		ISO ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; Phenylephrine affects the reaction [ANGPT1 protein results in increased expression of ILK protein]
Phenylephrine results in increased expression of ANGPT1 mRNA; Phenylephrine results in increased expression of ANGPT1 protein 		CTD PMID:18502941 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696 		JBrowse link
G Angptl4 angiopoietin-like 4 decreases expression EXP Phenylephrine results in decreased expression of ANGPTL4 mRNA CTD PMID:18158353 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:15,252,473...15,258,681 		JBrowse link
G Apoe apolipoprotein E affects response to substance ISO APOE protein affects the susceptibility to Phenylephrine CTD PMID:17899169 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855 		JBrowse link
G Areg amphiregulin increases expression EXP Phenylephrine results in increased expression of AREG mRNA CTD PMID:18158353 NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641 		JBrowse link
G Arhgef12 Rho guanine nucleotide exchange factor 12 decreases expression EXP Phenylephrine results in decreased expression of ARHGEF12 mRNA CTD PMID:18158353 NCBI chr 8:52,247,047...52,373,158
Ensembl chr 8:52,247,047...52,372,376 		JBrowse link
G Arrdc3 arrestin domain containing 3 decreases expression EXP Phenylephrine results in decreased expression of ARRDC3 mRNA CTD PMID:18158353 NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875 		JBrowse link
G Asb18 ankyrin repeat and SOCS box-containing 18 decreases expression EXP Phenylephrine results in decreased expression of ASB18 mRNA CTD PMID:18158353 NCBI chr 9:97,979,018...98,043,609
Ensembl chr 9:97,979,264...98,043,540 		JBrowse link
G Asb4 ankyrin repeat and SOCS box-containing 4 increases expression EXP Phenylephrine results in increased expression of ASB4 mRNA CTD PMID:18158353 NCBI chr 4:34,473,527...34,511,163
Ensembl chr 4:34,473,408...34,512,888 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP Phenylephrine results in increased expression of ASNS mRNA CTD PMID:18158353 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050 		JBrowse link
G Atf5 activating transcription factor 5 increases expression EXP Phenylephrine results in increased expression of ATF5 mRNA CTD PMID:18158353 NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:104,432,094...104,436,183 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Phenylephrine results in increased expression of ATP1B1 mRNA CTD PMID:11204457 NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
decreases expression
affects response to substance
increases expression
decreases activity 		ISO
EXP 		[Phenylephrine co-treated with ADRA1B protein] results in decreased expression of ATP2A2 protein
Phenylephrine results in decreased expression of ATP2A2 mRNA; Phenylephrine results in decreased expression of ATP2A2 protein
(+)-JQ1 compound inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Phenylephrine results in increased expression of ATP2A2 protein]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; Prazosin inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA]; THRB protein affects the reaction [Phenylephrine results in decreased expression of ATP2A2 protein]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of ATP2A2 mRNA]
ATP2A2 protein affects the susceptibility to Phenylephrine
Phenylephrine results in increased expression of ATP2A2 mRNA
Phenylephrine results in decreased activity of ATP2A2 protein 		CTD PMID:11499749 PMID:11577024 PMID:15795322 PMID:16236312 PMID:17287366 More... NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases response to substance ISO ATP2B4 protein results in increased susceptibility to Phenylephrine CTD PMID:12933703 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:47,711,121...47,758,876 		JBrowse link
G Atp9a ATPase phospholipid transporting 9A (putative) increases expression EXP Phenylephrine results in increased expression of ATP9A mRNA CTD PMID:18158353 NCBI chr 3:177,779,203...177,886,431
Ensembl chr 3:177,779,203...178,023,661 		JBrowse link
G Atxn1 ataxin 1 multiple interactions EXP Phenylephrine inhibits the reaction [Iodine-131 inhibits the reaction [PAFAH1B1 protein binds to ATXN1 protein]] CTD PMID:32278511 NCBI chr17:18,943,397...19,354,751
Ensembl chr17:19,208,200...19,356,790 		JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 decreases expression EXP Phenylephrine results in decreased expression of AUTS2 mRNA CTD PMID:18158353 NCBI chr12:29,739,138...30,830,386
Ensembl chr12:29,740,523...30,830,386 		JBrowse link
G Avp arginine vasopressin multiple interactions
increases secretion 		EXP Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein]; bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; Dexamethasone inhibits the reaction [Phenylephrine results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein] CTD PMID:2271928 PMID:11102496 NCBI chr 3:138,246,544...138,248,522
Ensembl chr 3:138,246,554...138,248,522 		JBrowse link
G Avpi1 arginine vasopressin-induced 1 increases expression EXP Phenylephrine results in increased expression of AVPI1 mRNA CTD PMID:18158353 NCBI chr 1:250,879,530...250,885,448
Ensembl chr 1:250,879,530...250,885,704 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Phenylephrine results in increased expression of BAD protein CTD PMID:31605733 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression EXP Phenylephrine results in increased expression of BAMBI mRNA CTD PMID:18158353 NCBI chr17:58,816,438...58,821,003
Ensembl chr17:58,816,442...58,821,247 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
multiple interactions 		EXP
ISO 		Phenylephrine results in decreased expression of BAX protein
Phenylephrine results in increased expression of BAX protein
PTHLH protein affects the reaction [Phenylephrine results in decreased expression of BAX protein] 		CTD PMID:19910689 PMID:31605733 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member multiple interactions
increases phosphorylation 		EXP ABL1 protein affects the reaction [Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein]]; ABL1 protein affects the reaction [Phenylephrine results in increased phosphorylation of BCAR1 protein]; Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein] CTD PMID:17615370 NCBI chr19:56,588,500...56,623,190
Ensembl chr19:56,588,500...56,623,190 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha decreases expression EXP Phenylephrine results in decreased expression of BCKDHA mRNA CTD PMID:18158353 NCBI chr 1:90,266,731...90,295,521
Ensembl chr 1:90,261,629...90,295,749 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression 		EXP
ISO 		BCL2 protein affects the reaction [Phenylephrine results in increased expression of TIMP1 protein]; Phenylephrine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]; Phenylephrine inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 mRNA]; Phenylephrine inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2 protein]; PTHLH protein affects the reaction [Phenylephrine results in increased expression of BCL2 mRNA]; PTHLH protein affects the reaction [Phenylephrine results in increased expression of BCL2 protein]
Phenylephrine results in decreased expression of BCL2 protein
Phenylephrine results in increased expression of BCL2 mRNA; Phenylephrine results in increased expression of BCL2 protein 		CTD PMID:11042672 PMID:19910689 PMID:31605733 PMID:35979984 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression 		EXP
ISO 		Phenylephrine inhibits the reaction [Doxorubicin results in decreased expression of BCL2L1 mRNA]; Phenylephrine inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2L1 mRNA]; Phenylephrine inhibits the reaction [Oxygen deficiency results in decreased expression of BCL2L1 protein]
Phenylephrine results in decreased expression of BCL2L1 protein 		CTD PMID:11042672 PMID:31605733 PMID:35979984 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 increases expression EXP Phenylephrine results in increased expression of BDH1 mRNA CTD PMID:18158353 NCBI chr11:82,806,125...82,848,133
Ensembl chr11:82,807,503...82,842,636 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 decreases expression EXP Phenylephrine results in decreased expression of BDH2 mRNA CTD PMID:18158353 NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:226,376,356...226,397,006 		JBrowse link
G Bdkrb2 bradykinin receptor B2 affects response to substance
increases expression 		ISO
EXP 		BDKRB2 affects the susceptibility to Phenylephrine
Phenylephrine results in increased expression of BDKRB2 mRNA 		CTD PMID:10614985 PMID:18158353 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:130,237,255...130,267,209 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Phenylephrine results in increased expression of BDNF mRNA CTD PMID:18158353 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression EXP phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression EXP phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes RGD PMID:26873969 RGD:11526363 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:22,098,470...22,105,172 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression
increases expression 		EXP Phenylephrine results in decreased expression of BMP7 mRNA
phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes 		CTD
RGD		 PMID:18158353 PMID:26873969 RGD:11526363 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:182,052,337...182,135,137 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP Phenylephrine results in increased expression of BNIP3L mRNA CTD PMID:16291751 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282 		JBrowse link
G Boll boule homolog, RNA binding protein decreases expression EXP Phenylephrine results in decreased expression of BOLL mRNA CTD PMID:18158353 NCBI chr 9:64,225,411...64,354,394
Ensembl chr 9:64,228,472...64,354,319 		JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression 		EXP Phenylephrine promotes the reaction [BRD4 protein binds to NPPA promoter]
Phenylephrine results in increased expression of BRD4 protein 		CTD PMID:23939492 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression EXP Phenylephrine results in increased expression of BTG3 mRNA CTD PMID:18158353 NCBI chr11:30,517,068...30,532,981
Ensembl chr11:30,517,072...30,533,082 		JBrowse link
G Ca1 carbonic anhydrase 1 decreases activity ISO Phenylephrine results in decreased activity of CA1 protein CTD PMID:28800181 NCBI chr 2:88,550,681...88,593,454
Ensembl chr 2:88,495,475...88,593,454 		JBrowse link
G Ca4 carbonic anhydrase 4 increases expression EXP Phenylephrine results in increased expression of CA4 protein CTD PMID:17124262 NCBI chr10:70,325,102...70,333,916
Ensembl chr10:70,325,358...70,333,916 		JBrowse link
G Cabin1 calcineurin binding protein 1 multiple interactions EXP CABIN1 protein inhibits the reaction [Phenylephrine results in increased activity of PPP3CB protein]; CABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; CABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 mRNA]; CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 protein] CTD PMID:10655507 PMID:17060317 NCBI chr20:12,892,750...13,014,801
Ensembl chr20:12,892,771...13,014,800 		JBrowse link
G Cadps calcium dependent secretion activator decreases expression EXP Phenylephrine results in decreased expression of CADPS mRNA CTD PMID:18158353 NCBI chr15:14,719,078...15,173,218
Ensembl chr15:14,720,726...15,173,211 		JBrowse link
G Calca calcitonin-related polypeptide alpha affects response to substance ISO
EXP 		CALCA protein affects the susceptibility to Phenylephrine CTD PMID:11728430 PMID:18055875 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Calcrl calcitonin receptor like receptor multiple interactions EXP [Phenylephrine co-treated with Isoproterenol] results in increased expression of CALCRL mRNA CTD PMID:17250927 NCBI chr 3:89,835,071...89,932,616
Ensembl chr 3:89,835,077...89,887,350 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression EXP Phenylephrine results in decreased expression of CAMK2A mRNA CTD PMID:18158353 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta multiple interactions EXP CAMK2D protein promotes the reaction [Phenylephrine results in increased activity of MAP3K5 protein] CTD PMID:15629441 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression
decreases activity 		EXP
ISO 		Phenylephrine results in increased expression of CAR2 mRNA; Phenylephrine results in increased expression of CAR2 protein
Phenylephrine results in decreased activity of CA2 protein 		CTD PMID:17124262 PMID:28800181 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:88,462,872...88,478,064 		JBrowse link
G Casp2 caspase 2 affects activity ISO Phenylephrine affects the activity of CASP2 protein CTD PMID:31605733 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity 		EXP
ISO 		Phenylephrine inhibits the reaction [Oxygen deficiency results in increased activity of CASP3 protein]
Phenylephrine results in increased activity of CASP3 protein 		CTD PMID:11042672 PMID:31605733 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp8 caspase 8 affects activity ISO Phenylephrine affects the activity of CASP8 protein CTD PMID:31605733 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699 		JBrowse link
G Casp9 caspase 9 increases activity ISO Phenylephrine results in increased activity of CASP9 protein CTD PMID:31605733 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Casr calcium-sensing receptor multiple interactions EXP Phenylephrine inhibits the reaction [Spermine binds to and results in increased activity of CASR protein] CTD PMID:11071898 NCBI chr11:77,738,398...77,813,639
Ensembl chr11:77,740,614...77,810,167 		JBrowse link
G Cat catalase multiple interactions
decreases expression 		EXP CAT protein inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein]; CAT protein inhibits the reaction [Phenylephrine results in increased expression of DNM1L protein]; CAT protein inhibits the reaction [Phenylephrine results in increased expression of FIS1 protein]; CAT protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAT protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Phenylephrine results in decreased expression of CAT protein 		CTD PMID:16513848 PMID:18171680 PMID:20886221 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Sodium, Dietary affects the reaction [CAV1 protein results in increased susceptibility to Phenylephrine] CTD PMID:18178722 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740 		JBrowse link
G Cav3 caveolin 3 multiple interactions
increases expression
decreases response to substance
affects localization 		ISO
EXP 		CAV3 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 protein]; CAV3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; CAV3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Phenylephrine results in increased expression of CAV3 mRNA]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Phenylephrine results in increased expression of CAV3 protein]; Cyclosporine inhibits the reaction [Phenylephrine results in increased expression of CAV3 mRNA]; Cyclosporine inhibits the reaction [Phenylephrine results in increased expression of CAV3 protein]; KN 62 inhibits the reaction [Phenylephrine results in increased expression of CAV3 mRNA]; KN 62 inhibits the reaction [Phenylephrine results in increased expression of CAV3 protein]
Phenylephrine results in increased expression of CAV3 mRNA; Phenylephrine results in increased expression of CAV3 protein
CAV3 protein results in decreased susceptibility to Phenylephrine
Phenylephrine affects the localization of CAV3 protein 		CTD PMID:12847114 PMID:15725944 PMID:19299911 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:147,137,797...147,153,967 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression 		EXP 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in increased expression of CCL2 mRNA]; parthenolide inhibits the reaction [Phenylephrine results in increased expression of CCL2 mRNA]
Phenylephrine results in increased expression of CCL2 mRNA; Phenylephrine results in increased expression of CCL2 protein 		CTD PMID:15721863 PMID:15728586 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccl27 C-C motif chemokine ligand 27 increases expression EXP Phenylephrine results in increased expression of CCL27 mRNA CTD PMID:18158353 NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522 		JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions
increases expression 		ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA]; calphostin C inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA]; chelerythrine inhibits the reaction [Phenylephrine results in increased expression of CCN1 mRNA]
Phenylephrine results in increased expression of CCN1 mRNA; Phenylephrine results in increased expression of CCN1 protein 		CTD PMID:15117851 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Phenylephrine results in increased expression of CCN2 mRNA; Phenylephrine results in increased expression of CCN2 protein CTD PMID:15276029 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression 		EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of CCND1 protein] CTD PMID:12163013 PMID:15603588 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810 		JBrowse link
G Ccnd2 cyclin D2 increases expression EXP Phenylephrine results in increased expression of CCND2 protein CTD PMID:12163013 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301 		JBrowse link
G Ccnd3 cyclin D3 multiple interactions
increases expression 		EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of CCND3 protein] CTD PMID:12163013 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033 		JBrowse link
G Ccnt1 cyclin T1 multiple interactions EXP Phenylephrine inhibits the reaction [HEXIM1 protein binds to CCNT1 protein] CTD PMID:17459355 NCBI chr 7:131,566,176...131,596,988
Ensembl chr 7:131,566,176...131,596,938 		JBrowse link
G Cd200 Cd200 molecule decreases expression EXP Phenylephrine results in decreased expression of CD200 mRNA CTD PMID:18158353 NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569 		JBrowse link
G Cdh2 cadherin 2 increases expression EXP Phenylephrine results in increased expression of CDH2 protein CTD PMID:17526999 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288 		JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression EXP Phenylephrine results in increased expression of CDK2 protein CTD PMID:15603588 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Phenylephrine results in increased expression of CDK4 protein CTD PMID:15603588 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
increases stability 		ISO
EXP 		Phenylephrine results in increased expression of CDKN1A mRNA; Phenylephrine results in increased expression of CDKN1A protein
Phenylephrine results in increased stability of CDKN1A mRNA 		CTD PMID:10766810 PMID:15603588 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression EXP Phenylephrine results in increased expression of CDKN1B CTD PMID:15603588 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression EXP Phenylephrine results in decreased expression of CEBPA mRNA CTD PMID:19443575 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309 		JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions EXP [Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein; [Phenylephrine co-treated with 6-hydroxy-10-chlorobenzo(c)quinolizinium] results in increased activity of CFTR protein; Glyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein] CTD PMID:17596272 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:47,526,735...47,694,643 		JBrowse link
G Chchd6 coiled-coil-helix-coiled-coil-helix domain containing 6 increases expression EXP Phenylephrine results in increased expression of CHCHD6 mRNA CTD PMID:18158353 NCBI chr 4:123,360,729...123,581,429
Ensembl chr 4:123,349,187...123,581,421 		JBrowse link
G Clic2 chloride intracellular channel 2 decreases expression EXP Phenylephrine results in decreased expression of CLIC2 mRNA CTD PMID:18158353 NCBI chr20:154,630...169,655
Ensembl chr20:154,255...169,648 		JBrowse link
G Clic4 chloride intracellular channel 4 increases expression EXP Phenylephrine results in increased expression of CLIC4 mRNA CTD PMID:18158353 NCBI chr 5:152,737,371...152,797,118
Ensembl chr 5:152,737,371...152,797,118 		JBrowse link
G Clu clusterin increases expression EXP Phenylephrine results in increased expression of CLU mRNA; Phenylephrine results in increased expression of CLU protein CTD PMID:19443575 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860 		JBrowse link
G Cnn1 calponin 1 increases expression EXP Phenylephrine results in increased expression of CNN1 mRNA CTD PMID:18158353 NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression EXP Phenylephrine results in decreased expression of COL18A1 mRNA CTD PMID:18158353 NCBI chr20:11,473,645...11,582,111
Ensembl chr20:11,473,645...11,582,112 		JBrowse link
G Colec12 collectin sub-family member 12 decreases expression EXP Phenylephrine results in decreased expression of COLEC12 mRNA CTD PMID:18158353 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297 		JBrowse link
G Corin corin, serine peptidase increases expression EXP Phenylephrine results in increased expression of CORIN mRNA CTD PMID:15191894 NCBI chr14:36,034,613...36,264,671
Ensembl chr14:36,034,993...36,264,649 		JBrowse link
G Cox11 cytochrome c oxidase copper chaperone COX11 decreases expression
multiple interactions 		EXP Phenylephrine results in decreased expression of COX11 protein
Copper Sulfate inhibits the reaction [Phenylephrine results in decreased expression of COX11 protein]; periodate-oxidized adenosine inhibits the reaction [Phenylephrine results in decreased expression of COX11 protein]; VEGFA protein inhibits the reaction [Phenylephrine results in decreased expression of COX11 protein] 		CTD PMID:23818984 PMID:25107896 NCBI chr10:75,955,825...75,962,398
Ensembl chr10:75,955,783...75,963,489 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 multiple interactions
decreases expression 		EXP Copper Sulfate inhibits the reaction [Phenylephrine results in decreased expression of COX17 protein]; periodate-oxidized adenosine inhibits the reaction [Phenylephrine results in decreased expression of COX17 protein]; VEGFA protein inhibits the reaction [Phenylephrine results in decreased expression of COX17 protein] CTD PMID:23818984 PMID:25107896 NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 decreases expression
multiple interactions 		EXP Phenylephrine results in decreased expression of COX4I1 protein
Copper Sulfate inhibits the reaction [Phenylephrine results in decreased expression of COX4I1 protein]; periodate-oxidized adenosine inhibits the reaction [Phenylephrine results in decreased expression of COX4I1 protein] 		CTD PMID:23818984 NCBI chr19:65,630,383...65,636,623
Ensembl chr19:65,630,432...65,636,624 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B multiple interactions
decreases expression
increases expression 		EXP 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in decreased expression of CPT1B mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of CPT1B protein]; dorsomorphin promotes the reaction [Phenylephrine results in decreased expression of CPT1B mRNA]; dorsomorphin promotes the reaction [Phenylephrine results in decreased expression of CPT1B protein]
Phenylephrine results in decreased expression of CPT1B mRNA; Phenylephrine results in decreased expression of CPT1B protein
Phenylephrine results in increased expression of CPT1B mRNA 		CTD PMID:11879187 PMID:15721863 PMID:19699196 NCBI chr 7:122,370,974...122,380,473
Ensembl chr 7:122,370,444...122,380,036 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; Phenylephrine promotes the reaction [CREB1 protein binds to CREBBP protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein; Prazosin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; Propranolol inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein]; RPS6KA5 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of CREB1 protein] CTD PMID:14741741 PMID:15522277 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339 		JBrowse link
G Crebbp CREB binding protein multiple interactions
increases response to substance 		EXP [Phenylephrine results in increased activity of CREBBP protein] which results in increased expression of NPPA protein; CREBBP protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Phenylephrine promotes the reaction [CREB1 protein binds to CREBBP protein]; Phenylephrine promotes the reaction [NR3C2 protein binds to CREBBP protein]; Phenylephrine results in increased expression of and results in increased localization of CREBBP protein; Phenylephrine results in increased phosphorylation of and results in increased activity of CREBBP protein
CREBBP protein results in increased susceptibility to Phenylephrine 		CTD PMID:11705990 PMID:12477714 PMID:15006641 PMID:15522277 PMID:19966502 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,822,620...11,968,266 		JBrowse link
G Crem cAMP responsive element modulator increases expression EXP Phenylephrine results in increased expression of CREM mRNA CTD PMID:12791704 PMID:18158353 NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein multiple interactions EXP ABL1 protein affects the reaction [Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein]]; ABL1 protein affects the reaction [Phenylephrine promotes the reaction [CRK protein binds to WASL protein]]; Phenylephrine promotes the reaction [BCAR1 protein binds to CRK protein] CTD PMID:17615370 NCBI chr10:61,028,736...61,054,971
Ensembl chr10:61,028,757...61,082,988 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Phenylephrine results in decreased expression of CSNK2A1 mRNA CTD PMID:18158353 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 increases expression EXP Phenylephrine results in increased expression of CSPG4 mRNA CTD PMID:18158353 NCBI chr 8:66,160,942...66,195,987
Ensembl chr 8:66,160,942...66,200,806 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 increases expression EXP Phenylephrine results in increased expression of CSRP2 mRNA CTD PMID:18158353 NCBI chr 7:48,235,415...48,254,049
Ensembl chr 7:48,235,383...48,266,238 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases localization EXP Phenylephrine results in increased localization of CSRP3 protein CTD PMID:19376126 NCBI chr 1:107,664,338...107,682,916
Ensembl chr 1:107,664,338...107,682,916 		JBrowse link
G Cth cystathionine gamma-lyase increases activity EXP Phenylephrine results in increased activity of CTH protein CTD PMID:18184479 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:249,634,731...249,661,066 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP Phenylephrine promotes the reaction [CTNNB1 protein binds to NPPA promoter] CTD PMID:19799869 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Ctsc cathepsin C decreases expression EXP Phenylephrine results in decreased expression of CTSC mRNA CTD PMID:18158353 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:151,441,032...151,474,082 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Phenylephrine results in decreased expression of CXCL1 mRNA CTD PMID:18158353 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Phenylephrine results in decreased expression of CXCL10 mRNA CTD PMID:18158353 NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression EXP Phenylephrine results in decreased expression of CXCL11 mRNA CTD PMID:18158353 NCBI chr14:15,973,728...15,976,503
Ensembl chr14:15,973,720...15,976,567 		JBrowse link
G Cxxc4 CXXC finger protein 4 decreases expression EXP Phenylephrine results in decreased expression of CXXC4 mRNA CTD PMID:18158353 NCBI chr 2:225,329,044...225,363,347 JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression EXP Phenylephrine results in increased expression of CYP11B2 mRNA CTD PMID:19966502 NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:108,689,165...108,694,921 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Prazosin inhibits the reaction [Phenylephrine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]] CTD PMID:16510159 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression EXP Phenylephrine results in increased expression of CYP26B1 mRNA CTD PMID:18158353 NCBI chr 4:118,599,356...118,616,176
Ensembl chr 4:118,599,356...118,616,176 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions
increases response to substance
affects response to substance 		EXP 20-hydroxy-5,8,11,14-eicosatetraenoic acid affects the reaction [CYP4A1 protein affects the susceptibility to Phenylephrine]; 20-hydroxy-5,8,11,14-eicosatetraenoic acid inhibits the reaction [DDMS inhibits the reaction [CYP4A1 protein results in increased susceptibility to Phenylephrine]]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [CYP4A1 protein results in increased susceptibility to Phenylephrine]; DDMS inhibits the reaction [CYP4A1 protein results in increased susceptibility to Phenylephrine] CTD PMID:11124159 PMID:12388396 NCBI chr 5:134,360,096...134,374,233
Ensembl chr 5:134,360,111...134,374,231 		JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Phenylephrine results in increased expression of CYP51 mRNA CTD PMID:18158353 NCBI chr 4:30,991,693...31,010,147
Ensembl chr 4:30,991,613...31,010,450 		JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Phenylephrine results in decreased expression of DAPK1 mRNA CTD PMID:18158353 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581 		JBrowse link
G Dgke diacylglycerol kinase epsilon multiple interactions ISO DGKE protein inhibits the reaction [Phenylephrine results in increased abundance of Diglycerides]; DGKE protein inhibits the reaction [Phenylephrine results in increased localization of PRKCA protein]; DGKE protein inhibits the reaction [Phenylephrine results in increased localization of PRKCE protein] CTD PMID:18487437 NCBI chr10:74,348,931...74,374,509
Ensembl chr10:74,350,246...74,374,478 		JBrowse link
G Dgkz diacylglycerol kinase zeta multiple interactions ISO DGKZ protein inhibits the reaction [Phenylephrine results in increased abundance of Diglycerides]; DGKZ protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:16380548 NCBI chr 3:98,359,804...98,401,847
Ensembl chr 3:98,359,804...98,401,951 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP Phenylephrine results in increased expression of DHCR7 mRNA CTD PMID:18158353 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:208,444,434...208,461,382 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases activity
increases expression 		EXP Phenylephrine results in increased activity of DIO2 protein
Phenylephrine results in increased expression of DIO2 mRNA 		CTD PMID:15345674 NCBI chr 6:115,396,308...115,410,594
Ensembl chr 6:115,396,308...115,410,594 		JBrowse link
G Dnah12 dynein, axonemal, heavy chain 12 decreases expression EXP Phenylephrine results in decreased expression of DNAH12 mRNA CTD PMID:18158353 NCBI chr16:1,932,776...2,099,391
Ensembl chr16:1,944,752...2,099,373 		JBrowse link
G Dnajb5 DnaJ heat shock protein family (Hsp40) member B5 increases expression EXP Phenylephrine results in increased expression of DNAJB5 mRNA CTD PMID:18158353 NCBI chr 5:61,972,637...61,981,887
Ensembl chr 5:61,972,706...61,981,860 		JBrowse link
G Dnm1l dynamin 1-like increases expression
multiple interactions 		EXP Phenylephrine results in increased expression of DNM1L protein
CAT protein inhibits the reaction [Phenylephrine results in increased expression of DNM1L protein]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of DNM1L protein]; sanglifehrin A inhibits the reaction [Phenylephrine results in increased expression of DNM1L protein] 		CTD PMID:20886221 NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420 		JBrowse link
G Doc2g double C2-like domains, gamma decreases expression EXP Phenylephrine results in decreased expression of DOC2G mRNA CTD PMID:18158353 NCBI chr 1:210,724,868...210,729,352
Ensembl chr 1:210,725,748...210,730,048 		JBrowse link
G Dpt dermatopontin decreases expression EXP Phenylephrine results in decreased expression of DPT mRNA CTD PMID:18158353 NCBI chr13:79,656,341...79,684,759
Ensembl chr13:79,655,985...79,684,758 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression EXP Phenylephrine results in increased expression of DUSP1 mRNA CTD PMID:18158353 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of RPS6KB1 protein] CTD PMID:15757502 NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833 		JBrowse link
G E2f3 E2F transcription factor 3 increases expression EXP Phenylephrine results in increased expression of E2F3 protein CTD PMID:12682052 NCBI chr17:34,810,355...34,887,725
Ensembl chr17:34,809,998...34,887,725 		JBrowse link
G E2f4 E2F transcription factor 4 increases expression EXP Phenylephrine results in increased expression of E2F4 protein CTD PMID:12682052 NCBI chr19:50,084,335...50,091,731
Ensembl chr19:50,084,335...50,091,834 		JBrowse link
G E2f5 E2F transcription factor 5 increases expression EXP Phenylephrine results in increased expression of E2F5 protein CTD PMID:12682052 NCBI chr 2:88,718,567...88,734,143
Ensembl chr 2:88,718,567...88,734,143 		JBrowse link
G Ece1 endothelin converting enzyme 1 increases expression EXP Phenylephrine results in increased expression of ECE1 mRNA CTD PMID:15007106 NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719 		JBrowse link
G Ecm1 extracellular matrix protein 1 increases expression EXP Phenylephrine results in increased expression of ECM1 mRNA CTD PMID:18158353 NCBI chr 2:185,976,439...185,981,656
Ensembl chr 2:185,976,440...185,981,606 		JBrowse link
G Edf1 endothelial differentiation-related factor 1 multiple interactions
increases expression
affects response to substance 		EXP MBF1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]
Phenylephrine results in increased expression of MBF1
MBF1 protein affects the susceptibility to Phenylephrine 		CTD PMID:12729799 NCBI chr 3:28,764,906...28,779,499 JBrowse link
G Edn1 endothelin 1 multiple interactions
increases response to substance
increases expression 		ISO
EXP 		EP300 protein promotes the reaction [[Phenylephrine results in increased activity of GATA4 protein] which results in increased expression of EDN1 mRNA]
Phenylephrine promotes the reaction [GATA4 protein binds to EDN1 promoter]; Polyphenols inhibits the reaction [EDN1 protein results in increased susceptibility to Phenylephrine]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of EDN1 protein]; Y 27632 inhibits the reaction [Phenylephrine results in increased expression of EDN1 mRNA]; ZFPM2 protein inhibits the reaction [Phenylephrine results in increased expression of EDN1 mRNA]
Phenylephrine results in increased expression of EDN1 mRNA; Phenylephrine results in increased expression of EDN1 protein 		CTD PMID:10788492 PMID:11739382 PMID:12724418 PMID:15007106 PMID:15220332 More... NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] which results in decreased susceptibility to Phenylephrine; phosphoramidon inhibits the reaction [Phenylephrine results in increased expression of EDNRA protein] CTD PMID:15007106 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:47,137,771...47,201,284 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Phenylephrine results in increased expression of EDNRB protein CTD PMID:15007106 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; ADAM17 protein affects the reaction [Phenylephrine results in increased cleavage of and results in increased secretion of EGF protein]; Phenylephrine results in increased cleavage of and results in increased secretion of EGF protein CTD PMID:16760267 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation 		ISO
EXP 		Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein]; Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein
Phenylephrine results in increased phosphorylation of EGFR protein
[EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] 		CTD PMID:14676212 PMID:16760267 PMID:18360054 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 increases expression EXP Phenylephrine results in increased expression of EGLN3 mRNA CTD PMID:18158353 NCBI chr 6:77,385,549...77,411,015
Ensembl chr 6:77,385,549...77,411,015 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression 		ISO
EXP 		EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 mRNA]; EGR1 protein affects the reaction [[Isoproterenol co-treated with Phenylephrine] results in increased expression of SLC8A1 protein]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of ACTA1 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of SP1 mRNA]
Phenylephrine results in increased expression of EGR1; Phenylephrine results in increased expression of EGR1 mRNA
Phenylephrine promotes the reaction [EGR1 protein binds to FGF2 promoter] 		CTD PMID:7905536 PMID:10710348 PMID:10779383 PMID:15621046 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions
increases phosphorylation 		EXP CGP 57380 inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4E protein]; Sirolimus inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4E protein]; U 0126 inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4E protein] CTD PMID:15757502 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases phosphorylation 		EXP 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; rottlerin inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; Sirolimus inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein]; U 0126 inhibits the reaction [Phenylephrine results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12411397 PMID:12720544 PMID:12935885 PMID:15757502 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions
increases phosphorylation
increases expression 		EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of ELK1 mRNA]; MAPK1 protein affects the reaction [Phenylephrine results in increased expression of ELK1 mRNA]; MAPK3 protein affects the reaction [Phenylephrine results in increased expression of ELK1 mRNA]; Phenylephrine promotes the reaction [ELK1 protein modified form binds to FOS promoter]
Phenylephrine results in increased phosphorylation of ELK1 protein 		CTD PMID:10900171 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249 		JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 increases expression EXP Phenylephrine results in increased expression of ELOVL5 mRNA CTD PMID:18158353 NCBI chr 8:87,671,164...87,737,618
Ensembl chr 8:87,671,159...87,737,616 		JBrowse link
G Eno2 enolase 2 increases expression EXP Phenylephrine results in increased expression of ENO2 mRNA CTD PMID:18158353 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:159,258,371...159,267,220 		JBrowse link
G Eno3 enolase 3 increases expression EXP Phenylephrine results in increased expression of ENO3 mRNA CTD PMID:18158353 NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,866,101...55,874,540 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions
increases expression
increases response to substance 		ISO
EXP 		EP300 protein promotes the reaction [[Phenylephrine results in increased activity of GATA4 protein] which results in increased expression of EDN1 mRNA]
Phenylephrine results in increased expression of EP300 mRNA; Phenylephrine results in increased expression of EP300 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of EP300 mRNA]; [Phenylephrine results in increased activity of EP300 protein] which results in increased expression of NPPA protein; [SIRT6 protein co-treated with EP300 protein] affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [SIRT6 protein co-treated with EP300 protein] affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; anacardic acid inhibits the reaction [Phenylephrine results in increased expression of EP300 protein]; EP300 protein affects the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; EP300 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; EP300 protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; EP300 protein promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; MAPK1 protein promotes the reaction [Phenylephrine results in increased expression of EP300 mRNA]; Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]; Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of EP300 protein; Resveratrol inhibits the reaction [Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]]; Resveratrol inhibits the reaction [Phenylephrine results in increased expression of EP300 protein]; SIRT6 protein inhibits the reaction [Phenylephrine results in increased expression of EP300 protein]; ZFPM2 protein inhibits the reaction [Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]]
EP300 protein results in increased susceptibility to Phenylephrine 		CTD PMID:11705990 PMID:12477714 PMID:12724418 PMID:15006641 PMID:15220332 More... NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression EXP Phenylephrine results in decreased expression of EPAS1 mRNA CTD PMID:18158353 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729 		JBrowse link
G Epb41l4b erythrocyte membrane protein band 4.1 like 4B increases expression EXP Phenylephrine results in increased expression of EPB41L4B mRNA CTD PMID:18158353 NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752 		JBrowse link
G Epha4 Eph receptor A4 decreases expression EXP Phenylephrine results in decreased expression of EPHA4 mRNA CTD PMID:18158353 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755 		JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression EXP Phenylephrine results in decreased expression of EPHX2 mRNA CTD PMID:18158353 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine co-treated with Acetylcholine]; ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine co-treated with Nitroprusside]; ESR1 protein affects the susceptibility to [Lipopolysaccharides co-treated with Phenylephrine] CTD PMID:17158209 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 multiple interactions EXP EYA2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 protein]; EYA2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein] CTD PMID:17327491 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034 		JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression EXP Phenylephrine results in decreased expression of FABP4 mRNA CTD PMID:18158353 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972 		JBrowse link
G Fads3 fatty acid desaturase 3 increases expression EXP Phenylephrine results in increased expression of FADS3 mRNA CTD PMID:18158353 NCBI chr 1:216,110,547...216,127,431
Ensembl chr 1:216,110,201...216,141,758 		JBrowse link
G Fam110b family with sequence similarity 110, member B decreases expression EXP Phenylephrine results in decreased expression of FAM110B mRNA CTD PMID:18158353 NCBI chr 5:23,587,093...23,727,188
Ensembl chr 5:23,586,867...23,799,583 		JBrowse link
G Fbn1 fibrillin 1 multiple interactions ISO FBN1 protein affects the reaction [Phenylephrine results in increased secretion of Epoprostenol metabolite]; FBN1 protein affects the reaction [Phenylephrine results in increased secretion of Thromboxane A2 metabolite]; FBN1 protein affects the reaction [PTGS1 protein affects the susceptibility to Phenylephrine] CTD PMID:17641673 NCBI chr 3:133,007,693...133,204,277
Ensembl chr 3:133,008,361...133,204,283 		JBrowse link
G Fdx1 ferredoxin 1 increases expression EXP Phenylephrine results in increased expression of FDX1 mRNA CTD PMID:18158353 NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583 		JBrowse link
G Fgf12 fibroblast growth factor 12 increases expression EXP Phenylephrine results in increased expression of FGF12 mRNA CTD PMID:18158353 NCBI chr11:85,501,947...86,069,543
Ensembl chr11:85,501,936...86,069,543 		JBrowse link
G Fgf18 fibroblast growth factor 18 increases expression EXP Phenylephrine results in increased expression of FGF18 mRNA CTD PMID:18158353 NCBI chr10:18,210,240...18,241,929
Ensembl chr10:18,210,512...18,240,933 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP Phenylephrine promotes the reaction [EGR1 protein binds to FGF2 promoter] CTD PMID:10779383 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Phenylephrine results in increased expression of FHL1 mRNA CTD PMID:18158353 NCBI chr  X:139,592,794...139,652,290
Ensembl chr  X:139,592,604...139,652,282 		JBrowse link
G Fhl2 four and a half LIM domains 2 decreases response to substance EXP FHL2 gene mutant form results in decreased susceptibility to Phenylephrine CTD PMID:25358972 NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326 		JBrowse link
G Fis1 fission, mitochondrial 1 increases expression
multiple interactions 		EXP Phenylephrine results in increased expression of FIS1 protein
CAT protein inhibits the reaction [Phenylephrine results in increased expression of FIS1 protein]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of FIS1 protein]; sanglifehrin A inhibits the reaction [Phenylephrine results in increased expression of FIS1 protein] 		CTD PMID:20886221 NCBI chr12:25,345,239...25,360,135
Ensembl chr12:25,345,239...25,349,335 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression 		EXP FLT1 protein promotes the reaction [Phenylephrine results in increased activity of PRKG1 protein]
Phenylephrine results in increased expression of FLT1 protein 		CTD PMID:19542178 PMID:24903162 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Phenylephrine results in increased expression of FN1 protein CTD PMID:11821714 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
affects expression
affects response to substance
increases expression 		ISO
EXP 		[Phenylephrine co-treated with Isoproterenol] results in increased expression of FOS mRNA; U 0126 inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA]
Phenylephrine affects the expression of FOS protein
FOS protein affects the susceptibility to Phenylephrine
Phenylephrine results in increased expression of FOS; Phenylephrine results in increased expression of FOS mRNA; Phenylephrine results in increased expression of FOS protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA]; [Phenylephrine co-treated with Adenosine Triphosphate] results in increased expression of FOS mRNA; AGT protein promotes the reaction [Phenylephrine results in increased expression of FOS mRNA]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA]; N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA]; Phenylephrine promotes the reaction [ELK1 protein modified form binds to FOS promoter]; Phenylephrine promotes the reaction [JUN protein binds to FOS protein]; PRKCZ protein affects the reaction [Phenylephrine results in increased expression of FOS mRNA]; Troglitazone inhibits the reaction [Phenylephrine results in increased expression of FOS protein] 		CTD PMID:7844257 PMID:7900855 PMID:7905536 PMID:8750937 PMID:8809800 More... NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases activity
increases expression 		EXP Phenylephrine results in increased activity of FOSB protein
Phenylephrine results in increased expression of FOSB 		CTD PMID:7905536 PMID:15949472 NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions EXP Phenylephrine promotes the reaction [FOXO1 protein results in increased expression of TNF mRNA]; Phenylephrine results in increased expression of and results in decreased phosphorylation of and affects the localization of FOXO1 protein CTD PMID:16020479 NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419 		JBrowse link
G Fstl3 follistatin like 3 affects expression EXP Phenylephrine affects the expression of FSTL3 mRNA CTD PMID:18158353 NCBI chr 7:10,574,195...10,579,844
Ensembl chr 7:10,574,186...10,590,509 		JBrowse link
G Fxyd5 FXYD domain-containing ion transport regulator 5 increases expression EXP Phenylephrine results in increased expression of FXYD5 mRNA CTD PMID:18158353 NCBI chr 1:95,395,327...95,404,722
Ensembl chr 1:95,395,146...95,405,364 		JBrowse link
G Galnt13 polypeptide N-acetylgalactosaminyltransferase 13 decreases expression EXP Phenylephrine results in decreased expression of GALNT13 mRNA CTD PMID:18158353 NCBI chr 3:59,312,628...59,969,633
Ensembl chr 3:59,383,516...59,965,379 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression EXP Phenylephrine results in decreased expression of GAMT mRNA CTD PMID:18158353 NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083 		JBrowse link
G Gata4 GATA binding protein 4 multiple interactions
increases activity
increases expression
increases acetylation
affects response to substance 		ISO
EXP 		EP300 protein promotes the reaction [[Phenylephrine results in increased activity of GATA4 protein] which results in increased expression of EDN1 mRNA]
Phenylephrine results in increased expression of GATA4 protein
Phenylephrine results in increased acetylation of GATA4 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]; latrunculin B inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]; MAPK1 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]; MAPK3 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]; Phenylephrine promotes the reaction [GATA4 protein binds to EDN1 promoter]; Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of GATA4 protein; Y 27632 inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]; ZFPM2 protein inhibits the reaction [Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]]; ZFPM2 protein inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]
GATA4 protein affects the susceptibility to Phenylephrine
[Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNA 		CTD PMID:10710348 PMID:10788492 PMID:11739382 PMID:12724418 PMID:15220332 More... NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609 		JBrowse link
G Gdf15 growth differentiation factor 15 affects expression ISO Phenylephrine affects the expression of GDF15 mRNA CTD PMID:19505289 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO Phenylephrine promotes the reaction [Ethylene Dibromide results in increased activity of GGT1 protein] CTD PMID:12628311 NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
affects response to substance 		EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of GJA1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of GJA1 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased expression of GJA1 mRNA]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased expression of GJA1 protein]; SB 203580 inhibits the reaction [Phenylephrine results in increased expression of GJA1 mRNA]; SB 203580 inhibits the reaction [Phenylephrine results in increased expression of GJA1 protein]
Phenylephrine results in increased expression of GJA1 mRNA; Phenylephrine results in increased expression of GJA1 protein
GJA1 protein affects the susceptibility to Phenylephrine 		CTD PMID:16352648 PMID:18445782 PMID:18593691 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:36,302,352...36,319,689 		JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression EXP Phenylephrine results in decreased expression of GJA5 mRNA CTD PMID:18158353 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512 		JBrowse link
G Gla galactosidase, alpha affects response to substance ISO GLA protein affects the susceptibility to Phenylephrine CTD PMID:18565198 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:102,056,718...102,073,915 		JBrowse link
G Glrx3 glutaredoxin 3 affects response to substance
increases expression
multiple interactions 		EXP GLRX3 protein affects the susceptibility to Phenylephrine
Phenylephrine results in increased expression of GLRX3 mRNA
GLRX3 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCA protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCE protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCZ protein] 		CTD PMID:16809552 NCBI chr 1:201,671,410...201,701,722
Ensembl chr 1:201,671,481...201,701,717 		JBrowse link
G Gmfg glia maturation factor, gamma increases expression EXP Phenylephrine results in increased expression of GMFG mRNA CTD PMID:18158353 NCBI chr 1:92,856,154...92,866,722
Ensembl chr 1:92,854,995...92,866,723 		JBrowse link
G Gnaq G protein subunit alpha q multiple interactions EXP RTKI cpd inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]] CTD PMID:14676212 NCBI chr 1:222,852,453...223,098,754
Ensembl chr 1:222,852,097...223,126,742 		JBrowse link
G Gnas GNAS complex locus affects response to substance EXP GNAS protein affects the susceptibility to Phenylephrine CTD PMID:10696522 NCBI chr 3:183,489,648...183,554,570
Ensembl chr 3:183,503,243...183,554,536 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions
increases secretion
decreases secretion 		EXP alfuzosin inhibits the reaction [Phenylephrine results in decreased secretion of GNRH1 protein]; alfuzosin inhibits the reaction [Phenylephrine results in increased secretion of GNRH1 protein]; Testosterone affects the reaction [Phenylephrine affects the secretion of GNRH1 protein] CTD PMID:1975657 NCBI chr15:46,147,878...46,152,086
Ensembl chr15:46,148,301...46,148,977
Ensembl chr15:46,148,301...46,148,977 		JBrowse link
G Gpm6a glycoprotein m6a decreases expression EXP Phenylephrine results in decreased expression of GPM6A mRNA CTD PMID:18158353 NCBI chr16:43,374,385...43,706,461
Ensembl chr16:43,374,385...43,706,705 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions
increases expression 		ISO
EXP 		[Phenylephrine co-treated with ADRA1B protein] results in increased expression of GRK2 protein
Phenylephrine results in increased expression of GRK2 protein
GRK2 protein affects the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; GRK2 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; GRK2 protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of AKT1 protein]; GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein] 		CTD PMID:11499749 PMID:28759639 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:211,009,978...211,031,015 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation 		EXP GRK2 protein affects the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein]; SGK1 protein promotes the reaction [Phenylephrine results in increased phosphorylation of GSK3B protein] CTD PMID:15795328 PMID:28759639 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression EXP Phenylephrine results in decreased expression of GSTK1 mRNA CTD PMID:18158353 NCBI chr 4:72,085,532...72,089,934
Ensembl chr 4:72,085,531...72,089,927 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 decreases expression EXP Phenylephrine results in decreased expression of GSTM3 mRNA CTD PMID:18158353 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731 		JBrowse link
G Gys2 glycogen synthase 2 decreases activity EXP Phenylephrine results in decreased activity of GYS2 protein CTD PMID:747652 NCBI chr 4:177,096,063...177,137,236
Ensembl chr 4:177,096,063...177,137,236 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP Phenylephrine results in decreased expression of HAMP mRNA CTD PMID:18158353 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:95,298,307...95,300,297 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression EXP Phenylephrine results in increased expression of DTR mRNA CTD PMID:18158353 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220 		JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Phenylephrine results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein CTD PMID:19124542 NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,652,656...87,694,244 		JBrowse link
G Hdgfl2 HDGF like 2 decreases expression EXP Phenylephrine results in decreased expression of HDGFL2 mRNA CTD PMID:18158353 NCBI chr 9:996,687...1,016,352
Ensembl chr 9:996,758...1,016,735 		JBrowse link
G Herc3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 increases expression EXP Phenylephrine results in increased expression of HERC3 mRNA CTD PMID:18158353 NCBI chr 4:89,282,374...89,372,656
Ensembl chr 4:89,282,445...89,372,652 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 multiple interactions EXP Phenylephrine inhibits the reaction [HEXIM1 protein binds to CCNT1 protein] CTD PMID:17459355 NCBI chr10:88,562,889...88,565,001
Ensembl chr10:88,560,519...88,580,000 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
decreases expression
decreases response to substance 		ISO HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]
Phenylephrine results in decreased expression of HEY2 mRNA
HEY2 protein results in decreased susceptibility to Phenylephrine 		CTD PMID:16603706 PMID:20001863 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression EXP Phenylephrine results in increased expression of HIGD1A mRNA CTD PMID:18158353 NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Phenylephrine results in increased expression of HMGCS1 mRNA CTD PMID:18158353 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Phenylephrine results in increased expression of HOMER1 mRNA alternative form CTD PMID:16786172 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657 		JBrowse link
G Hspb3 heat shock protein family B (small) member 3 increases expression EXP Phenylephrine results in increased expression of HSPB3 mRNA CTD PMID:18158353 NCBI chr 2:47,028,451...47,029,165
Ensembl chr 2:47,024,757...47,029,373 		JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression
increases expression 		EXP Phenylephrine results in increased expression of ID1 mRNA
phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes 		CTD
RGD		 PMID:18158353 PMID:26873969 RGD:11526363 NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685 		JBrowse link
G Id4 inhibitor of DNA binding 4 increases expression EXP Phenylephrine results in increased expression of ID4 mRNA CTD PMID:18158353 NCBI chr17:16,595,724...16,598,293
Ensembl chr17:16,595,724...16,598,492 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression EXP Phenylephrine results in increased expression of IDI1 mRNA CTD PMID:18158353 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:66,539,763...66,547,524 		JBrowse link
G Ier3 immediate early response 3 decreases response to substance
affects localization 		ISO IER3 protein results in decreased susceptibility to Phenylephrine
Phenylephrine affects the localization of IER3 protein 		CTD PMID:11934837 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377 		JBrowse link
G Igf1 insulin-like growth factor 1 affects response to substance EXP IGF1 protein affects the susceptibility to Phenylephrine CTD PMID:11159833 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764 		JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 affects response to substance EXP IGFBP4 protein affects the susceptibility to Phenylephrine CTD PMID:11159833 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Phenylephrine results in decreased expression of IGFBP5 mRNA CTD PMID:18158353 NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390 		JBrowse link
G Igtp interferon gamma induced GTPase decreases expression EXP Phenylephrine results in decreased expression of IGTP mRNA CTD PMID:18158353 NCBI chr10:42,875,047...42,882,866
Ensembl chr10:42,876,790...42,882,858 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases activity
multiple interactions 		EXP Phenylephrine results in increased activity of IKBKB protein
IKBKB protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA] 		CTD PMID:11381115 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases response to substance
affects response to substance 		EXP Halothane affects the reaction [IL1B protein affects the susceptibility to Phenylephrine]
IL1B protein results in decreased susceptibility to Phenylephrine 		CTD PMID:11506125 PMID:13679239 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
decreases expression 		EXP Phenylephrine results in increased expression of IL6 mRNA
[resveratrol co-treated with Phenylephrine] results in increased expression of IL6 mRNA
Phenylephrine results in decreased expression of IL6 mRNA 		CTD PMID:11406463 PMID:12423672 PMID:22748497 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Ilk integrin-linked kinase multiple interactions
affects localization 		ISO
EXP 		Phenylephrine affects the reaction [ANGPT1 protein results in increased expression of ILK protein]
Phenylephrine affects the localization of ILK protein
ILK protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA] 		CTD PMID:16170337 PMID:18502941 NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:169,498,681...169,506,964 		JBrowse link
G Inha inhibin subunit alpha increases expression EXP Phenylephrine results in increased expression of INHA mRNA CTD PMID:18158353 NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009 		JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression EXP Phenylephrine results in decreased expression of IRF7 mRNA CTD PMID:18158353 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression EXP Phenylephrine results in decreased expression of ISG15 mRNA CTD PMID:18158353 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656 		JBrowse link
G Itga9 integrin subunit alpha 9 increases expression EXP Phenylephrine results in increased expression of ITGA9 mRNA CTD PMID:18158353 NCBI chr 8:127,185,244...127,493,296
Ensembl chr 8:127,169,226...127,493,296 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression EXP Phenylephrine results in increased expression of ITGB3BP mRNA CTD PMID:18158353 NCBI chr 5:119,575,657...119,640,974
Ensembl chr 5:119,575,248...119,640,997 		JBrowse link
G Itgb8 integrin subunit beta 8 increases expression EXP Phenylephrine results in increased expression of ITGB8 mRNA CTD PMID:18158353 NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:146,165,484...146,351,245 		JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 increases activity
multiple interactions 		ISO Phenylephrine results in increased activity of ITPR2 protein
[Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of ACTA1 mRNA; [Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of NPPA mRNA 		CTD PMID:15201137 NCBI chr 4:180,759,325...181,165,361
Ensembl chr 4:180,760,442...181,164,763 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation
increases expression
increases activity
affects response to substance 		ISO
EXP 		[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of JUN mRNA]
Phenylephrine results in increased phosphorylation of JUN protein
Phenylephrine results in increased expression of JUN; Phenylephrine results in increased expression of JUN mRNA; Phenylephrine results in increased expression of JUN protein
Phenylephrine results in increased activity of JUN protein
JUN protein affects the susceptibility to Phenylephrine
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased expression of JUN mRNA]; CEP-11004 inhibits the reaction [Phenylephrine results in increased phosphorylation of JUN protein]; JUN gene mutant form inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; JUN gene mutant form inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MAPK1 protein promotes the reaction [Phenylephrine results in increased expression of JUN mRNA]; MAPK3 protein promotes the reaction [Phenylephrine results in increased expression of JUN mRNA]; Phenylephrine inhibits the reaction [MAPK7 protein results in increased expression of JUN protein]; Phenylephrine promotes the reaction [JUN protein binds to FOS protein]; pyrazolanthrone inhibits the reaction [Phenylephrine results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased expression of JUN mRNA]; RPS6KA5 protein promotes the reaction [Phenylephrine results in increased expression of JUN mRNA]; SB 203580 inhibits the reaction [Phenylephrine results in increased expression of JUN mRNA] 		CTD PMID:7905536 PMID:10710348 PMID:11799083 PMID:12169099 PMID:12574153 More... NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression
increases activity 		EXP Phenylephrine results in increased expression of JUNB
Phenylephrine results in increased activity of JUNB protein 		CTD PMID:7905536 PMID:15949472 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression 		ISO JUND protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Phenylephrine results in decreased expression of JUND mRNA 		CTD PMID:16690042 NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,764,985...18,782,148 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 multiple interactions
decreases expression
decreases response to substance 		EXP CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 mRNA]; CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 protein]; KCND2 protein inhibits the reaction [Phenylephrine results in increased activity of NFATC1 protein]; KCND2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
Phenylephrine results in decreased expression of KCND2 mRNA; Phenylephrine results in decreased expression of KCND2 protein
KCND2 protein results in decreased susceptibility to Phenylephrine 		CTD PMID:12403671 PMID:16385079 PMID:17060317 NCBI chr 4:50,741,595...51,243,540
Ensembl chr 4:50,742,839...51,243,522 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 multiple interactions
decreases expression 		ISO
EXP 		[KCND3 protein co-treated with ADRA1A protein] affects the susceptibility to Phenylephrine; chelerythrine inhibits the reaction [Phenylephrine results in decreased activity of KCND3 protein alternative form]; Phenylephrine results in decreased activity of [KCND3 protein alternative form co-treated with ADRA1A protein]
Phenylephrine results in decreased expression of KCND3 mRNA; Phenylephrine results in decreased expression of KCND3 protein 		CTD PMID:11249870 PMID:11709419 PMID:16385079 PMID:17060317 NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:195,626,316...195,843,690 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Phenylephrine affects the reaction [KCNH2 protein results in increased transport of Potassium] CTD PMID:19419905 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:11,692,980...11,751,421 		JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 multiple interactions
decreases expression 		EXP MAPK8 protein affects the reaction [Phenylephrine results in decreased expression of KCNIP2 mRNA]
Phenylephrine results in decreased expression of KCNIP2 mRNA; Phenylephrine results in decreased expression of KCNIP2 mRNA alternative form; Phenylephrine results in decreased expression of KCNIP2 protein 		CTD PMID:16385079 PMID:17060317 PMID:18158353 NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:254,590,175...254,613,898 		JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 increases expression EXP Phenylephrine results in increased expression of KDELR3 mRNA CTD PMID:18158353 NCBI chr 7:112,959,632...112,969,858
Ensembl chr 7:112,959,718...112,969,858 		JBrowse link
G Kdr kinase insert domain receptor decreases expression
multiple interactions
increases expression 		EXP Phenylephrine results in decreased expression of KDR mRNA
Copper inhibits the reaction [Phenylephrine results in increased expression of KDR protein] 		CTD PMID:18158353 PMID:24903162 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192 		JBrowse link
G Kif5b kinesin family member 5B decreases expression EXP Phenylephrine results in decreased expression of KIF5B mRNA CTD PMID:18158353 NCBI chr17:56,185,386...56,222,990
Ensembl chr17:56,185,380...56,223,008 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions
decreases expression 		EXP Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]; SK-7041 inhibits the reaction [Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]]
Phenylephrine results in decreased expression of KLF4 mRNA; Phenylephrine results in decreased expression of KLF4 protein 		CTD PMID:19729022 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592 		JBrowse link
G Klhl24 kelch-like family member 24 decreases expression EXP Phenylephrine results in decreased expression of KLHL24 mRNA CTD PMID:18158353 NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050 		JBrowse link
G Kmt2e lysine methyltransferase 2E decreases expression EXP Phenylephrine results in decreased expression of KMT2E mRNA CTD PMID:18158353 NCBI chr 4:12,550,570...12,655,329
Ensembl chr 4:12,550,570...12,619,721 		JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression EXP Phenylephrine results in increased expression of LAMC1 mRNA CTD PMID:18158353 NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986 		JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression EXP Phenylephrine results in increased expression of LAMC2 mRNA CTD PMID:18158353 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP Phenylephrine results in increased expression of LDLR mRNA CTD PMID:18158353 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Lgals3bp galectin 3 binding protein decreases expression EXP Phenylephrine results in decreased expression of LGALS3BP mRNA CTD PMID:18158353 NCBI chr10:104,118,510...104,127,848
Ensembl chr10:104,118,510...104,127,848 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 affects localization EXP Phenylephrine affects the localization of LIMS1 protein CTD PMID:16170337 NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,852,996...26,961,606 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Phenylephrine results in increased expression of LMCD1 mRNA CTD PMID:18158353 NCBI chr 4:146,948,993...147,007,878
Ensembl chr 4:146,948,958...147,007,875 		JBrowse link
G Lpl lipoprotein lipase affects response to substance ISO LPL protein affects the susceptibility to Phenylephrine CTD PMID:11786490 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107 		JBrowse link
G Lrrc27 leucine rich repeat containing 27 decreases expression EXP Phenylephrine results in decreased expression of LRRC27 mRNA CTD PMID:18158353 NCBI chr 1:203,433,463...203,464,683
Ensembl chr 1:203,434,355...203,464,676 		JBrowse link
G Lyl1 LYL1, basic helix-loop-helix family member increases expression EXP Phenylephrine results in increased expression of LYL1 mRNA CTD PMID:18158353 NCBI chr19:40,356,967...40,359,834
Ensembl chr19:40,354,819...40,359,834 		JBrowse link
G Mafk MAF bZIP transcription factor K increases expression EXP Phenylephrine results in increased expression of MAFK mRNA CTD PMID:18158353 NCBI chr12:19,948,473...19,970,351
Ensembl chr12:19,948,476...19,959,192 		JBrowse link
G Man1a1 mannosidase, alpha, class 1A, member 1 decreases expression EXP Phenylephrine results in decreased expression of MAN1A mRNA CTD PMID:18158353 NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [MAOB protein co-treated with MAOA protein] affects the susceptibility to Phenylephrine CTD PMID:11834493 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Maob monoamine oxidase B multiple interactions ISO [MAOB protein co-treated with MAOA protein] affects the susceptibility to Phenylephrine CTD PMID:11834493 NCBI chr  X:8,490,405...8,594,065
Ensembl chr  X:8,490,344...8,594,375 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP MAP2K1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MAP2K1 protein affects the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAP2K1 protein affects the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:10888249 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 multiple interactions EXP MEKK1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:10727428 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions
increases activity 		EXP CAMK2D protein promotes the reaction [Phenylephrine results in increased activity of MAP3K5 protein]; KN 93 inhibits the reaction [Phenylephrine results in increased activity of MAP3K5 protein] CTD PMID:15629441 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 increases phosphorylation
multiple interactions 		EXP phenylephrin increases phosphorylation of Map3k7 protein in neonatal cardiomyocytes
Phenylephrine promotes the reaction [Map3k7 protein binds to Tab1 protein in neonatal cardiomyocytes]
Phenylephrine promotes the reaction [Map3k7 protein binds to Ripk2 protein]
Phenylephrine increases phosphorylation of Map3k7 protein in neonatal cardiomyocytes 		RGD PMID:32971071 PMID:35352799 PMID:34733837 PMID:35490166 RGD:155791643, RGD:155804287, RGD:155791674, RGD:155791668 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
increases expression
increases activity
affects phosphorylation 		ISO
EXP 		[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein; [Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein; [Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein; [Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK1 protein; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; CAV3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK1 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK1 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein; RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; RGS4 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Phenylephrine results in increased expression of MAPK1 protein modified form
Phenylephrine results in increased activity of MAPK1 protein
Phenylephrine affects the phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased activity of MAPK1 protein]; [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; [Phenylephrine results in increased phosphorylation of MAPK1 protein] which affects the expression of TGFB1I1 protein; ADAM17 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; BMY 7378 inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; calphostin C inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAT protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Docosahexaenoic Acids inhibits the reaction [Phenylephrine results in increased phosphorylation of and affects the localization of MAPK1 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; latrunculin B inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Lovastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein affects the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MAPK1 protein affects the reaction [Phenylephrine results in increased expression of ELK1 mRNA]; MAPK1 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]; MAPK1 protein promotes the reaction [Phenylephrine results in increased expression of EP300 mRNA]; MAPK1 protein promotes the reaction [Phenylephrine results in increased expression of JUN mRNA]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Phenylephrine results in increased phosphorylation of and affects the localization of MAPK1 protein; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein; Prazosin inhibits the reaction [Phenylephrine results in increased activity of MAPK1 protein]; Prazosin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; RGS2 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; rottlerin inhibits the reaction [Phenylephrine results in increased activity of MAPK1 protein]; rottlerin promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Ruthenium Red inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; SLC9A1 protein promotes the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Phenylephrine results in increased activity of MAPK1 protein]; Y 27632 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Pertussis Toxin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein; Prazosin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein] 		CTD PMID:10422649 PMID:10660688 PMID:10727428 PMID:10788492 PMID:10888249 More... NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk10 mitogen activated protein kinase 10 multiple interactions ISO MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Phenylephrine] CTD PMID:16949803 NCBI chr14:6,802,247...7,094,103
Ensembl chr14:6,802,295...7,094,100 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation EXP Phenylephrine results in increased phosphorylation of MAPK14 protein CTD PMID:15757502 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
increases expression
increases activity
affects phosphorylation 		ISO
EXP 		[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein; [Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein; [Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein; [Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK3 protein; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Carvedilol inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; CAV3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1A protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1B protein] results in increased phosphorylation of MAPK3 protein]; Phentolamine inhibits the reaction [[Phenylephrine co-treated with ADRA1D protein] results in increased phosphorylation of MAPK3 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein; RGS3 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; RGS4 protein affects the reaction [[Timolol co-treated with Phenylephrine] results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Phenylephrine results in increased expression of MAPK3 protein modified form
Phenylephrine results in increased activity of MAPK3 protein
Phenylephrine affects the phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased activity of MAPK3 protein]; [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; [Phenylephrine results in increased phosphorylation of MAPK3 protein] which affects the expression of TGFB1I1 protein; ADAM17 protein affects the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; BMY 7378 inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; calphostin C inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CAT protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cyclosporine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [Phenylephrine results in increased phosphorylation of and affects the localization of MAPK3 protein]; DUSP6 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; latrunculin B inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MAP2K1 protein affects the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MAPK3 protein affects the reaction [Phenylephrine results in increased expression of ELK1 mRNA]; MAPK3 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]; MAPK3 protein promotes the reaction [Phenylephrine results in increased expression of JUN mRNA]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Phenylephrine results in increased phosphorylation of and affects the localization of MAPK3 protein; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein; Prazosin inhibits the reaction [Phenylephrine results in increased activity of MAPK3 protein]; Prazosin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; RGS2 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; rottlerin inhibits the reaction [Phenylephrine results in increased activity of MAPK3 protein]; rottlerin promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Ruthenium Red inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; SLC9A1 protein promotes the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Phenylephrine results in increased activity of MAPK3 protein]; Y 27632 inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Atorvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Pertussis Toxin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein; Prazosin inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] 		CTD PMID:10422649 PMID:10660688 PMID:10727428 PMID:10788492 PMID:10888249 More... NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 multiple interactions EXP Phenylephrine inhibits the reaction [MAPK7 protein results in increased expression of JUN protein] CTD PMID:12574153 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation 		EXP GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]; MAPK8 protein affects the reaction [Phenylephrine results in decreased expression of KCNIP2 mRNA]; Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein; RGS2 protein promotes the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]
Phenylephrine results in increased phosphorylation of MAPK8 protein 		CTD PMID:10727428 PMID:16385079 PMID:16517124 PMID:16809552 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 affects response to substance
multiple interactions 		EXP MAPK8IP1 protein affects the susceptibility to Phenylephrine
MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] 		CTD PMID:11513749 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:98,810,541...98,828,368 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
affects response to substance 		ISO
EXP 		MAPK10 protein affects the reaction [MAPK9 protein affects the susceptibility to Phenylephrine]
Phenylephrine results in increased phosphorylation of MAPK9 protein 		CTD PMID:10727428 PMID:16949803 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Masp1 MBL associated serine protease 1 decreases expression EXP Phenylephrine results in decreased expression of MASP1 mRNA CTD PMID:18158353 NCBI chr11:90,839,081...90,909,922
Ensembl chr11:90,839,061...90,917,470 		JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions
increases expression
increases activity 		ISO
EXP 		Go 6976 inhibits the reaction [Phenylephrine results in increased activity of MEF2C protein]
Phenylephrine results in increased expression of MEF2C mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phenylephrine results in increased expression of MEF2C mRNA]; KN 62 inhibits the reaction [Phenylephrine results in increased expression of MEF2C mRNA] 		CTD PMID:10737771 PMID:19124542 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640 		JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression EXP Phenylephrine results in decreased expression of MFAP4 mRNA CTD PMID:18158353 NCBI chr10:46,666,552...46,669,613
Ensembl chr10:46,655,722...46,669,740 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 decreases expression EXP Phenylephrine results in decreased expression of MFHAS1 mRNA CTD PMID:18158353 NCBI chr16:63,248,833...63,336,441
Ensembl chr16:63,250,455...63,336,602 		JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions 		EXP Phenylephrine results in decreased expression of MFN2 mRNA; Phenylephrine results in decreased expression of MFN2 protein
CAT protein inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein]; Ruthenium Red inhibits the reaction [Phenylephrine results in decreased expression of MFN2 protein] 		CTD PMID:17499311 PMID:20886221 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495 		JBrowse link
G Mgll monoglyceride lipase decreases expression EXP Phenylephrine results in decreased expression of MGLL mRNA CTD PMID:18158353 NCBI chr 4:122,749,436...122,851,440
Ensembl chr 4:122,749,436...122,851,440 		JBrowse link
G Mir21 microRNA 21 increases expression EXP Phenylephrine results in increased expression of MIR21 mRNA CTD PMID:17525252 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase increases expression ISO Phenylephrine results in increased expression of MLKL protein CTD PMID:31605733 NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression EXP Phenylephrine results in increased expression of MLLT11 mRNA CTD PMID:18158353 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:185,484,793...185,493,961 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO
EXP 		MMP2 protein affects the susceptibility to [Phenylephrine co-treated with Oxygen deficiency]
[Phenylephrine results in increased expression of AGT protein] which results in increased activity of MMP2 protein; Losartan inhibits the reaction [[Phenylephrine results in increased expression of AGT protein] which results in increased activity of MMP2 protein]; MMP2 protein affects the susceptibility to [Phenylephrine co-treated with Oxygen deficiency] 		CTD PMID:16251426 PMID:16980344 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO Phenylephrine results in increased expression of MMP9 mRNA CTD PMID:16574429 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442 		JBrowse link
G Mov10l1 Mov10 like RNA helicase 1 multiple interactions ISO
EXP 		MOV10L1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]
MOV10L1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MOV10L1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA] 		CTD PMID:11854500 PMID:12754203 NCBI chr 7:121,949,743...122,015,042
Ensembl chr 7:121,949,822...122,015,042 		JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression EXP Phenylephrine results in increased expression of MSMO1 mRNA CTD PMID:18158353 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445 		JBrowse link
G Msn moesin increases expression EXP Phenylephrine results in increased expression of MSN mRNA CTD PMID:18158353 NCBI chr  X:65,005,546...65,073,512
Ensembl chr  X:65,005,458...65,075,129 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression EXP Phenylephrine results in increased expression of MTHFD1L mRNA CTD PMID:18158353 NCBI chr 1:42,849,424...43,038,313
Ensembl chr 1:42,849,374...43,038,309 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP [Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Ethanol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] CTD PMID:12935885 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 increases expression EXP Phenylephrine results in increased expression of MUSTN1 mRNA CTD PMID:18158353 NCBI chr16:6,079,355...6,081,608
Ensembl chr16:6,079,277...6,081,586 		JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP Phenylephrine results in increased expression of MYBL1 mRNA CTD PMID:18158353 NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588 		JBrowse link
G Mybpc3 myosin binding protein C3 multiple interactions ISO MYBPC3 gene mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine]
MYBPC3 mutant form results in increased susceptibility to [Isoproterenol co-treated with Phenylephrine] 		CTD PMID:22076249 NCBI chr 3:97,550,974...97,569,216
Ensembl chr 3:97,551,061...97,569,216 		JBrowse link
G Myh14 myosin heavy chain 14 decreases expression EXP Phenylephrine results in decreased expression of MYH14 mRNA CTD PMID:18158353 NCBI chr 1:104,232,778...104,295,369
Ensembl chr 1:104,232,778...104,323,404 		JBrowse link
G Myh6 myosin heavy chain 6 multiple interactions
decreases expression 		EXP Prazosin inhibits the reaction [Phenylephrine results in decreased expression of MYH6 mRNA]; THRA protein affects the reaction [Phenylephrine results in decreased expression of MYH6 protein]; Triiodothyronine inhibits the reaction [Phenylephrine results in decreased expression of MYH6 mRNA] CTD PMID:11577024 PMID:15578571 PMID:15795322 PMID:17592507 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions
increases expression 		ISO
EXP 		CAV3 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 protein]
Phenylephrine results in increased expression of MYH7 mRNA
Phenylephrine results in increased expression of MYH7 mRNA; Phenylephrine results in increased expression of MYH7 protein
anacardic acid inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Colforsin inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; EP300 protein affects the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; EP300 protein promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; EYA2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 protein]; GRK2 protein affects the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; HS 142-1 promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Metoprolol promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; N(6)-phenyl-cAMP analog inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; S100A6 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; S100B protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; SIRT6 protein affects the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; SIRT6 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; SK-7041 inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; spiruchostatin A inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; THRB protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 protein]; trichostatin A inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Triiodothyronine inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; Y 27632 inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; ZFPM2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]
[Phenylephrine co-treated with Isoproterenol] results in increased expression of MYH7 mRNA; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA]; HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of MYH7 mRNA] 		CTD PMID:10642269 PMID:10710348 PMID:11249870 PMID:11513749 PMID:11577024 More... NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194 		JBrowse link
G Myl1 myosin, light chain 1 increases expression EXP Phenylephrine results in increased expression of MYL1 mRNA CTD PMID:18158353 Ensembl chr 9:75,887,227...75,907,971 JBrowse link
G Myl2 myosin light chain 2 multiple interactions
increases phosphorylation
increases expression 		EXP ADM protein inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; BQ 788 inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of MYL2 mRNA]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of MYL2 protein]; Uridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]
Phenylephrine results in increased phosphorylation of MYL2 protein 		CTD PMID:11470465 PMID:11513749 PMID:14676212 PMID:15007106 PMID:18202317 NCBI chr12:40,114,964...40,126,236
Ensembl chr12:40,114,958...40,129,149 		JBrowse link
G Myl7 myosin light chain 7 multiple interactions
increases phosphorylation 		ISO ML 7 inhibits the reaction [Phenylephrine results in increased phosphorylation of MYL7 protein]; wortmannin inhibits the reaction [Phenylephrine results in increased phosphorylation of MYL7 protein]; Y 27632 inhibits the reaction [Phenylephrine results in increased phosphorylation of MYL7 protein] CTD PMID:15621049 NCBI chr14:84,994,644...84,997,173
Ensembl chr14:84,993,736...84,997,372 		JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation EXP Phenylephrine results in increased phosphorylation of MYL9 protein CTD PMID:18835913 NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410 		JBrowse link
G Mylk3 myosin light chain kinase 3 increases phosphorylation ISO Phenylephrine results in increased phosphorylation of MYLK3 protein CTD PMID:18202317 NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827 		JBrowse link
G Myocd myocardin multiple interactions
increases expression 		EXP MYOCD protein affects the reaction [Phenylephrine results in increased expression of ACTA2 mRNA]; MYOCD protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of MYL2 protein]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]; Phenylephrine promotes the reaction [MYOCD protein binds to NPPA promoter]
Phenylephrine results in increased expression of MYOCD mRNA; Phenylephrine results in increased expression of MYOCD protein 		CTD PMID:14676212 PMID:16556869 NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819 		JBrowse link
G Myoz2 myozenin 2 multiple interactions
decreases response to substance 		ISO MYOZ2 protein inhibits the reaction [Phenylephrine results in increased expression of RCAN1 protein]
MYOZ2 protein results in decreased susceptibility to Phenylephrine 		CTD PMID:18025526 NCBI chr 2:213,826,052...213,852,778
Ensembl chr 2:213,826,052...213,852,914 		JBrowse link
G Nab1 Ngfi-A binding protein 1 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB1 mRNA CTD PMID:10710348 NCBI chr 9:56,545,547...56,585,045
Ensembl chr 9:56,545,729...56,614,210 		JBrowse link
G Nab2 Ngfi-A binding protein 2 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NAB2 mRNA] CTD PMID:10710348 NCBI chr 7:65,382,863...65,389,527
Ensembl chr 7:65,382,863...65,389,255 		JBrowse link
G Ncald neurocalcin delta increases expression EXP Phenylephrine results in increased expression of NCALD mRNA CTD PMID:18158353 NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases phosphorylation
increases expression 		EXP
ISO 		Phenylephrine results in increased phosphorylation of NCF1 protein
Phenylephrine results in increased expression of NCF1 mRNA 		CTD PMID:14656924 PMID:15936005 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions
affects localization 		EXP Cyclosporine inhibits the reaction [Phenylephrine results in increased localization of and results in increased activity of NFATC1 protein]; KCND2 protein inhibits the reaction [Phenylephrine results in increased activity of NFATC1 protein]; Phenylephrine results in increased localization of and results in increased activity of NFATC1 protein; sanggenone C inhibits the reaction [Phenylephrine affects the localization of NFATC1 protein] CTD PMID:12403671 PMID:19349967 PMID:28849031 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 increases localization
multiple interactions 		ISO Phenylephrine results in increased localization of NFATC3 protein
[NPPA protein results in increased activity of NPR1 protein] promotes the reaction [Phenylephrine results in increased localization of NFATC3 protein] 		CTD PMID:15939815 NCBI chr19:50,870,464...50,944,992
Ensembl chr19:50,870,489...50,944,992 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 multiple interactions
increases localization
affects localization 		ISO
EXP 		Cyclosporine inhibits the reaction [Phenylephrine results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [Phenylephrine results in increased localization of NFATC4 protein]
Phenylephrine affects the localization of NFATC4 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phenylephrine affects the localization of NFATC4 protein]; Cyclosporine inhibits the reaction [Phenylephrine results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [Phenylephrine results in increased localization of NFATC4 protein] 		CTD PMID:11044444 PMID:16055480 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated multiple interactions ISO U 0126 inhibits the reaction [Phenylephrine results in increased expression of NFIL3 mRNA] CTD PMID:12729908 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
increases degradation
decreases expression 		EXP 4-trifluoromethylsalicylic acid inhibits the reaction [Phenylephrine results in decreased expression of NFKBIA protein]; KN 93 inhibits the reaction [Phenylephrine results in increased degradation of NFKBIA protein]; NFKBIA protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11381115 PMID:15629441 PMID:16421291 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Nid2 nidogen 2 increases expression EXP Phenylephrine results in increased expression of NID2 mRNA CTD PMID:18158353 NCBI chr15:4,507,224...4,562,949
Ensembl chr15:4,506,756...4,562,949 		JBrowse link
G Nkx2-5 NK2 homeobox 5 multiple interactions ISO [Phenylephrine co-treated with Isoproterenol] results in increased expression of NKX2-5 mRNA CTD PMID:10710348 NCBI chr10:16,844,888...16,851,458
Ensembl chr10:16,848,582...16,851,452 		JBrowse link
G Nodal nodal growth differentiation factor affects expression EXP Phenylephrine affects the expression of NODAL mRNA; Phenylephrine affects the expression of NODAL protein CTD PMID:11029149 NCBI chr20:29,911,258...29,919,659
Ensembl chr20:29,911,258...29,919,659 		JBrowse link
G Nol3 nucleolar protein 3 decreases phosphorylation EXP Phenylephrine results in decreased phosphorylation of NOL3 protein CTD PMID:18171680 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:50,063,986...50,068,722 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases activity
decreases response to substance
affects response to substance 		ISO
EXP 		NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Acetylcholine]; NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Adenosine Diphosphate]; NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Calcimycin]; NOS2 protein affects the susceptibility to [Phenylephrine co-treated with Nitroprusside]
Prazosin inhibits the reaction [Phenylephrine results in increased expression of NOS2 mRNA]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of NOS2 protein]
Phenylephrine results in increased activity of NOS2 protein
NOS2 protein results in decreased susceptibility to Phenylephrine
NOS2 protein affects the susceptibility to Phenylephrine 		CTD PMID:11498454 PMID:15753950 PMID:15902277 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nos3 nitric oxide synthase 3 affects response to substance
decreases response to substance
multiple interactions
increases expression 		ISO
EXP 		NOS3 protein affects the susceptibility to Phenylephrine
NOS3 protein results in decreased susceptibility to Phenylephrine
NOS3 protein results in increased susceptibility to [Acetylcholine co-treated with Phenylephrine]
Phenylephrine results in increased expression of NOS3 mRNA; Phenylephrine results in increased expression of NOS3 protein 		CTD PMID:10954898 PMID:11504159 PMID:15381055 PMID:15753950 PMID:17403420 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664 		JBrowse link
G Nppa natriuretic peptide A increases secretion
increases expression
multiple interactions
decreases response to substance 		ISO
EXP 		Phenylephrine results in increased secretion of NPPA protein
phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes
Phenylephrine results in increased expression of NPPA mRNA; Phenylephrine results in increased expression of NPPA protein
(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; (+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; 2,3-diethyl-4,5-dipropyl-6-phenylpyridine-3-thiocarboxylate-5-carboxylate inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; 2-Chloroadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; 4-trifluoromethylsalicylic acid inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; 8-(3-chlorostyryl)caffeine inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; 8-(4-sulfophenyl)theophylline inhibits the reaction [[9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; [8-((4-chlorophenyl)thio)cyclic-3',5'-GMP co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [9-(2-hydroxy-3-nonyl)adenine co-treated with 4-nitrobenzylthioinosine] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [Phenylephrine co-treated with Oxygen deficiency] results in increased expression of NPPA mRNA; [Phenylephrine results in increased activity of CREBBP protein] which results in increased expression of NPPA protein; [Phenylephrine results in increased activity of EP300 protein] which results in increased expression of NPPA protein; [pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [SIRT6 protein co-treated with EP300 protein] affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ADM protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ADORA1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ADORA2A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ADORA3 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Aldosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; BQ 788 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; CABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; CABIN1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; Caffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; CEP-11004 inhibits the reaction [Phenylephrine results in increased secretion of NPPA protein]; chelerythrine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; chelerythrine promotes the reaction [2-aminoethoxydiphenyl borate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]]; Colforsin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Corticosterone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; CREBBP protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Docosahexaenoic Acids inhibits the reaction [Phenylephrine affects the expression of NPPA protein]; EP300 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; EYA2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; Fulvestrant inhibits the reaction [[Estradiol co-treated with Phenylephrine] results in increased expression of NPPA protein]; GLRX3 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; GRK2 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; HS 142-1 promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; HS 142-1 promotes the reaction [Phenylephrine results in increased secretion of NPPA protein]; IKBKB protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; ILK protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Isoproterenol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; JUN gene mutant form inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; KCND2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; kenpaullone promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; leptomycin B inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; MAP2K1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MAPK8IP1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MBF1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]; MEKK1 protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Metoprolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MOV10L1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MYOCD protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]; N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; N(6)-phenyl-cAMP analog inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; N-(2-methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; NFKBIA protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Ouabain promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; paricalcitol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]; Phenylephrine promotes the reaction [BRD4 protein binds to NPPA promoter]; Phenylephrine promotes the reaction [CTNNB1 protein binds to NPPA promoter]; Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]; Phenylephrine promotes the reaction [MYOCD protein binds to NPPA promoter]; polydatin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Prazosin inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; PRKCZ protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Propranolol promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Resveratrol inhibits the reaction [Phenylephrine promotes the reaction [EP300 protein binds to NPPA promoter]]; Resveratrol inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; RGS2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; RHOA protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; RTKI cpd inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Ruthenium Red inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; sanglifehrin A inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; SB 203580 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Sildenafil Citrate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; SIRT6 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; SK-7041 inhibits the reaction [Phenylephrine inhibits the reaction [KLF4 protein binds to NPPA promoter]]; SK-7041 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Spironolactone inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; TGFB1I1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA]; TGFB1I1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]; trichostatin A inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; triflusal inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; U 0126 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; Uridine Triphosphate inhibits the reaction [GNAQ protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [MYL2 protein promotes the reaction [Phenylephrine results in increased expression of NPPA protein]]; Uridine Triphosphate inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; xestospongin C inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Y 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Y 27632 inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]; ZFPM2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
NPPA protein results in decreased susceptibility to Phenylephrine
[NPPA protein results in increased activity of NPR1 protein] promotes the reaction [Phenylephrine results in increased localization of NFATC3 protein]; [Phenylephrine co-treated with ADRA1B protein] results in increased expression of NPPA protein; [Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA; [Phenylephrine results in increased activity of ITPR2 protein] which results in increased expression of NPPA mRNA; ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; DGKZ protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; EGR1 protein affects the reaction [[Phenylephrine co-treated with Isoproterenol] results in increased expression of NPPA mRNA]; HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; JUND protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; MOV10L1 protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA] 		CTD
RGD		 PMID:2847676 PMID:8188982 PMID:10642269 PMID:10655507 PMID:10679475 More... RGD:11526363 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493 		JBrowse link
G Nppb natriuretic peptide B multiple interactions
increases expression
increases secretion 		ISO
EXP 		ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; HEY2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]
phenylephrine increases expression of mRNA in neonatal rat cardiomyocytes
Phenylephrine results in increased expression of NPPB mRNA; Phenylephrine results in increased expression of NPPB protein
(+)-JQ1 compound inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; [pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; [SIRT6 protein co-treated with EP300 protein] affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; CEP-11004 inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; CEP-11004 inhibits the reaction [Phenylephrine results in increased secretion of NPPB protein]; EP300 protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; GRK2 protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; HS 142-1 promotes the reaction [Phenylephrine results in increased secretion of NPPB protein]; JUN gene mutant form inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MOV10L1 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; MYOCD protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; PRKCZ protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA]; Sildenafil Citrate inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; SIRT6 protein inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA] 		CTD
RGD		 PMID:10642269 PMID:11754973 PMID:11799083 PMID:11804996 PMID:11854500 More... RGD:11526363 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310 		JBrowse link
G Nppc natriuretic peptide C affects response to substance
multiple interactions 		EXP NPPC protein affects the susceptibility to Phenylephrine
SMR3B protein promotes the reaction [NPPC protein affects the susceptibility to Phenylephrine] 		CTD PMID:17026587 NCBI chr 9:94,767,986...94,772,186
Ensembl chr 9:94,767,986...94,772,186 		JBrowse link
G Npr1 natriuretic peptide receptor 1 multiple interactions ISO [NPPA protein results in increased activity of NPR1 protein] promotes the reaction [Phenylephrine results in increased localization of NFATC3 protein] CTD PMID:15939815 NCBI chr 2:178,231,766...178,247,591
Ensembl chr 2:178,231,766...178,247,088 		JBrowse link
G Npy neuropeptide Y multiple interactions ISO [Phenylephrine co-treated with ADRA1B protein] results in decreased expression of NPY protein; NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]] CTD PMID:10660688 PMID:11499749 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 multiple interactions ISO NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; NPY5R protein affects the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]] CTD PMID:10660688 NCBI chr16:27,822,055...27,830,012
Ensembl chr16:27,816,065...27,830,290 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance ISO NR1I2 protein affects the susceptibility to Phenylephrine CTD PMID:17159084 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP Phenylephrine results in increased expression of NR3C1 mRNA CTD PMID:16533503 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,522,783...31,643,843 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 multiple interactions
increases expression 		EXP Phenylephrine promotes the reaction [NR3C2 protein binds to CREBBP protein]; Phenylephrine results in increased expression of and results in increased localization of NR3C2 protein; Spironolactone inhibits the reaction [Phenylephrine results in increased localization of NR3C2 protein]
Phenylephrine results in increased expression of NR3C2 mRNA 		CTD PMID:16533503 PMID:19966502 NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Phenylephrine results in increased expression of NR4A3 mRNA CTD PMID:18158353 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression EXP Phenylephrine results in decreased expression of NREP mRNA CTD PMID:18158353 NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742 		JBrowse link
G Nrg1 neuregulin 1 decreases expression EXP Phenylephrine results in decreased expression of NRG1 mRNA; Phenylephrine results in decreased expression of NRG1 protein CTD PMID:16698793 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849 		JBrowse link
G Nts neurotensin decreases response to substance EXP NTS protein results in decreased susceptibility to Phenylephrine CTD PMID:2326505 NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:39,451,073...39,460,961 		JBrowse link
G Nup62 nucleoporin 62 multiple interactions
decreases expression 		EXP 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Phenylephrine results in decreased expression of NUP62 protein]; leptomycin B inhibits the reaction [Phenylephrine results in decreased expression of NUP62 protein]; trichostatin A inhibits the reaction [Phenylephrine results in decreased expression of NUP62 protein] CTD PMID:25341891 NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710 		JBrowse link
G Ogn osteoglycin decreases expression EXP Phenylephrine results in decreased expression of OGN mRNA CTD PMID:18158353 NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions
increases secretion 		EXP Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein] CTD PMID:11102496 PMID:15149956 NCBI chr 3:138,235,754...138,236,594
Ensembl chr 3:138,235,754...138,236,594 		JBrowse link
G P2rx5 purinergic receptor P2X 5 increases expression EXP Phenylephrine results in increased expression of P2RX5 mRNA CTD PMID:18158353 NCBI chr10:58,276,329...58,291,108
Ensembl chr10:58,276,257...58,287,935 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression EXP Phenylephrine results in increased expression of P4HA1 mRNA CTD PMID:18158353 NCBI chr20:27,784,696...27,895,785
Ensembl chr20:27,845,141...27,895,404 		JBrowse link
G Pacc1 proton activated chloride channel 1 decreases expression EXP Phenylephrine results in decreased expression of PACC1 mRNA CTD PMID:18158353 NCBI chr13:105,435,772...105,460,877
Ensembl chr13:105,435,799...105,461,095 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 multiple interactions EXP Phenylephrine inhibits the reaction [Iodine-131 inhibits the reaction [PAFAH1B1 protein binds to ATXN1 protein]]; Phenylephrine inhibits the reaction [Iodine-131 inhibits the reaction [PAFAH1B1 protein binds to SOX2 protein]]; Phenylephrine inhibits the reaction [Iodine-131 results in decreased expression of PAFAH1B1 protein] CTD PMID:32278511 NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Phenylephrine inhibits the reaction [Oxygen deficiency results in increased cleavage of PARP1 protein] CTD PMID:11042672 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Parva parvin, alpha affects localization EXP Phenylephrine affects the localization of PARVA protein CTD PMID:16170337 NCBI chr 1:175,981,725...176,139,523
Ensembl chr 1:175,981,432...176,139,526 		JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
multiple interactions 		EXP Phenylephrine results in increased expression of PCNA protein
Phenylephrine promotes the reaction [Iodine-131 results in increased expression of PCNA protein] 		CTD PMID:15603588 PMID:32278511 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pcp4 Purkinje cell protein 4 decreases expression EXP Phenylephrine results in decreased expression of PCP4 mRNA CTD PMID:18158353 NCBI chr11:49,229,185...49,331,186
Ensembl chr11:49,270,186...49,331,186 		JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 increases expression EXP Phenylephrine results in increased expression of PCSK6 mRNA CTD PMID:18158353 NCBI chr 1:128,839,742...129,038,087
Ensembl chr 1:128,839,232...129,052,128 		JBrowse link
G Pde1a phosphodiesterase 1A multiple interactions EXP PDE1A protein promotes the reaction [Phenylephrine results in decreased activity of PRKG1 protein] CTD PMID:19797176 NCBI chr 3:85,152,053...85,432,289
Ensembl chr 3:85,154,184...85,519,212 		JBrowse link
G Pde4b phosphodiesterase 4B increases expression EXP Phenylephrine results in increased expression of PDE4B mRNA CTD PMID:18158353 NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267 		JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions EXP PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPA mRNA]; PDE5A protein affects the reaction [Phenylephrine results in increased expression of NPPB mRNA] CTD PMID:18790048 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:213,542,923...213,684,298 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 decreases expression EXP Phenylephrine results in decreased expression of PDK2 mRNA CTD PMID:18158353 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:80,469,389...80,484,355 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 multiple interactions
decreases expression 		EXP 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid inhibits the reaction [Phenylephrine results in decreased expression of PDK4 mRNA]; parthenolide inhibits the reaction [Phenylephrine results in decreased expression of PDK4 mRNA] CTD PMID:15721863 PMID:15728586 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381 		JBrowse link
G Pdlim3 PDZ and LIM domain 3 increases expression EXP Phenylephrine results in increased expression of PDLIM3 mRNA CTD PMID:18158353 NCBI chr16:53,085,020...53,116,495
Ensembl chr16:53,085,020...53,116,217 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression EXP Phenylephrine results in increased expression of PEA15 mRNA CTD PMID:18158353 NCBI chr13:87,190,189...87,199,811
Ensembl chr13:87,187,295...87,199,859 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions ISO U 0126 inhibits the reaction [Phenylephrine results in increased expression of PER1 mRNA] CTD PMID:12729908 NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211 		JBrowse link
G Per2 period circadian regulator 2 multiple interactions ISO U 0126 inhibits the reaction [Phenylephrine results in increased expression of PER2 mRNA] CTD PMID:12729908 NCBI chr 9:99,454,828...99,497,069
Ensembl chr 9:99,454,830...99,496,993 		JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha decreases expression EXP Phenylephrine results in decreased expression of PEX11A mRNA CTD PMID:18158353 NCBI chr 1:143,089,410...143,096,491
Ensembl chr 1:143,089,410...143,096,645 		JBrowse link
G Pfkl phosphofructokinase, liver type increases expression EXP Phenylephrine results in increased expression of PFKL mRNA CTD PMID:18158353 NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,663,955...10,685,966 		JBrowse link
G Phgdh phosphoglycerate dehydrogenase increases expression EXP Phenylephrine results in increased expression of PHGDH mRNA CTD PMID:18158353 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789 		JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression EXP Phenylephrine results in increased expression of PHLDA1 mRNA CTD PMID:18158353 NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542 		JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting affects response to substance ISO PKD1 protein affects the susceptibility to Phenylephrine CTD PMID:18679710 NCBI chr10:14,077,733...14,125,682
Ensembl chr10:14,078,679...14,125,681 		JBrowse link
G Pklr pyruvate kinase L/R multiple interactions
decreases activity 		EXP Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] CTD PMID:747652 NCBI chr 2:176,840,779...176,849,637
Ensembl chr 2:176,840,764...176,849,644 		JBrowse link
G Pkp4 plakophilin 4 decreases expression EXP Phenylephrine results in decreased expression of PKP4 mRNA CTD PMID:18158353 NCBI chr 3:64,040,995...64,244,586
Ensembl chr 3:64,141,771...64,244,586 		JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression EXP Phenylephrine results in decreased expression of PLA2G2A mRNA CTD PMID:18158353 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297 		JBrowse link
G Pla2g6 phospholipase A2 group VI affects response to substance EXP PLA2G6 protein affects the susceptibility to Phenylephrine CTD PMID:17885217 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:112,731,803...112,771,609 		JBrowse link
G Plaat1 phospholipase A and acyltransferase 1 increases expression EXP Phenylephrine results in increased expression of PLAAT1 mRNA CTD PMID:18158353 NCBI chr11:85,022,297...85,041,999
Ensembl chr11:85,022,297...85,031,826 		JBrowse link
G Plcb1 phospholipase C beta 1 increases expression EXP Phenylephrine results in increased expression of PLCB1 mRNA CTD PMID:16714034 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:142,513,033...143,225,646 		JBrowse link
G Plcb3 phospholipase C beta 3 increases expression EXP Phenylephrine results in increased expression of PLCB3 mRNA CTD PMID:16714034 NCBI chr 1:213,572,499...213,589,585
Ensembl chr 1:213,574,166...213,589,583 		JBrowse link
G Plcd1 phospholipase C, delta 1 increases expression EXP Phenylephrine results in increased expression of PLCD1 mRNA CTD PMID:16714034 NCBI chr 8:127,672,955...127,695,939
Ensembl chr 8:127,672,980...127,695,939 		JBrowse link
G Plcg1 phospholipase C, gamma 1 increases expression EXP Phenylephrine results in increased expression of PLCG1 mRNA CTD PMID:16714034 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050 		JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases response to substance
increases secretion 		EXP
ISO 		Indomethacin inhibits the reaction [Phenylephrine results in increased secretion of POMC protein alternative form]
POMC protein results in increased susceptibility to Phenylephrine 		CTD PMID:2822310 PMID:3015460 PMID:10898105 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases expression 		EXP [pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]; [pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [pirinixic acid binds to PPARA protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA mRNA]; AICA ribonucleotide inhibits the reaction [Phenylephrine results in decreased expression of PPARA protein]
Phenylephrine results in decreased expression of PPARA mRNA; Phenylephrine results in decreased expression of PPARA protein 		CTD PMID:18701451 PMID:19699196 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased activity of PPARD protein] which results in decreased susceptibility to Phenylephrine; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA] CTD PMID:15721863 PMID:18701451 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions
increases phosphorylation 		EXP geranylgeraniol inhibits the reaction [Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]; Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R12A protein]; polydatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]; Simvastatin inhibits the reaction [Phenylephrine promotes the reaction [RHOA protein results in increased phosphorylation of PPP1R12A protein]]; Simvastatin inhibits the reaction [Phenylephrine results in increased phosphorylation of PPP1R12A protein]; Y 27632 inhibits the reaction