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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:5-methoxy-N,N-diisopropyltryptamine
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Accession:CHEBI:48282 term browser browse the term
Definition:A tryptamine that has formula C17H26N2O.
Synonyms:related_synonym: 5-MeO-DIPT;   5-methoxy-N,N-bis(1-methylethyl)-1H-indole-3-ethanamine;   N-(1-methylethyl)-N-{2-[5-(methyloxy)-1H-indol-3-yl]ethyl}propan-2-amine;   N-isopropyl-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]propan-2-amine;   N-{2-[5-(methyloxy)-1H-indol-3-yl]ethyl}-N-(propan-2-yl)propan-2-amine
 xref: Beilstein:482371;   CAS:4021-34-5;   DrugBank:DB01441
 xref_mesh: MESH:C033696
 chemrof_formula: C17H26N2O
 chemrof_smiles: COc1ccc2ncc(CCN(C(C)C)C(C)C)c2c1
 chemrof_inchikey: DNBPMBJFRRVTSJ-UHFFFAOYSA-N
 chemrof_inchi: InChI=1S/C17H26N2O/c1-12(2)19(13(3)4)9-8-14-11-18-17-7-6-15(20-5)10-16(14)17/h6-7,10-13,18H,8-9H2,1-5H3
 cyclic_relationship: has_functional_parent CHEBI:2089;   has_functional_parent CHEBI:48286


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5-methoxy-N,N-diisopropyltryptamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
multiple interactions 		ISO 5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein
[5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2B6 protein] which results in decreased metabolism of Bupropion 		CTD PMID:26599973 NCBI chr 1:90,780,468...90,859,852 JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases activity 		ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2C19 protein] which results in decreased metabolism of Omeprazole CTD PMID:26599973 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798 		JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 increases metabolic processing EXP CYP2D1 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine CTD PMID:18191824 NCBI chr 7:115,789,026...115,793,430
Ensembl chr 7:115,789,023...115,793,479 		JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 increases metabolic processing EXP CYP2D2 protein results in increased metabolism of 5-methoxy-N,N-diisopropyltryptamine CTD PMID:18191824 NCBI chr 7:115,815,212...115,819,281
Ensembl chr 7:115,815,212...115,819,281 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases activity 		ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2D6 protein] which results in decreased metabolism of Dextromethorphan CTD PMID:26599973 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity 		ISO [5-methoxy-N,N-diisopropyltryptamine analog results in decreased activity of CYP2E1 protein] which results in decreased metabolism of Chlorzoxazone CTD PMID:26599973 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        pharmaceutical 20359
          drug 20359
            central nervous system drug 16774
              psychotropic drug 15626
                hallucinogen 21
                  5-methoxy-N,N-diisopropyltryptamine 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      carbon group element atom 20712
                        carbon atom 20706
                          organic molecular entity 20706
                            organic molecule 20499
                              organic cyclic compound 20390
                                organic heterocyclic compound 19381
                                  organic heteropolycyclic compound 18616
                                    organic heterobicyclic compound 17442
                                      benzopyrrole 6369
                                        indoles 5968
                                          tryptamines 597
                                            5-methoxy-N,N-diisopropyltryptamine 6
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