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G |
Atm |
ATM serine/threonine kinase |
decreases expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of ATM mRNA |
CTD |
PMID:27601420 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atr |
ATR serine/threonine kinase |
decreases expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of ATR mRNA |
CTD |
PMID:27601420 |
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NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
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G |
Brca1 |
BRCA1, DNA repair associated |
decreases expression affects expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of BRCA1 protein octamethylcyclotetrasiloxane affects the expression of BRCA1 mRNA |
CTD |
PMID:27601420 |
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NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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G |
Brca2 |
BRCA2, DNA repair associated |
decreases expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of BRCA2 mRNA |
CTD |
PMID:27601420 |
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NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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G |
Chek1 |
checkpoint kinase 1 |
decreases expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of CHEK1 mRNA |
CTD |
PMID:27601420 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
decreases expression |
ISO |
octamethylcyclotetrasiloxane results in decreased expression of CHEK2 mRNA |
CTD |
PMID:27601420 |
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NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in decreased expression of and results in increased activity of CYP1A1 protein |
CTD |
PMID:36100151 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in decreased expression of and results in increased activity of CYP1A2 protein |
CTD |
PMID:36100151 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in increased expression of CYP2B1 protein octamethylcyclotetrasiloxane results in increased expression of and results in increased activity of CYP2B1 protein |
CTD |
PMID:15849718 PMID:36100151 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
increases expression multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in increased expression of CYP2B2 protein octamethylcyclotetrasiloxane results in increased expression of and results in increased activity of CYP2B2 protein |
CTD |
PMID:15849718 PMID:36100151 |
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NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
increases expression multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in increased expression of CYP3A2 protein octamethylcyclotetrasiloxane results in increased expression of and results in increased activity of CYP3A2 protein |
CTD |
PMID:15849718 PMID:36100151 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
increases expression multiple interactions |
EXP |
octamethylcyclotetrasiloxane results in increased expression of CYP3A23-3A1 protein octamethylcyclotetrasiloxane results in increased expression of and results in increased activity of CYP3A23-3A1 protein |
CTD |
PMID:15849718 PMID:36100151 |
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NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
octamethylcyclotetrasiloxane binds to and results in increased activity of ESR1 protein |
CTD |
PMID:17175556 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity |
ISO |
octamethylcyclotetrasiloxane results in increased activity of GPT protein |
CTD |
PMID:9924013 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity |
ISO |
octamethylcyclotetrasiloxane results in increased activity of NR1I2 protein |
CTD |
PMID:25680588 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
octamethylcyclotetrasiloxane results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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