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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:L-tryptophan derivative
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Accession:CHEBI:47994 term browser browse the term
Definition:A proteinogenic amino acid derivative resulting from reaction of L-tryptophan at the amino group or the carboxy group, or from the replacement of any hydrogen of L-tryptophan by a heteroatom.


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ilomastat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 multiple interactions EXP ilomastat inhibits the reaction [Mustard Gas results in increased expression of IL13 protein] CTD PMID:18852015 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions EXP ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 protein]; ilomastat inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP1 mRNA] CTD PMID:18837084 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA]; ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] CTD PMID:18837084 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
N-acetyl-L-tryptophan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP N-acetyltryptophan inhibits the reaction [Aluminum Chloride results in decreased activity of ACHE protein] CTD PMID:29185389 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Casp2 caspase 2 multiple interactions ISO N-acetyltryptophan inhibits the reaction [Cobalt-60 results in increased activity of CASP2 protein] CTD PMID:37702290 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO N-acetyltryptophan inhibits the reaction [Cobalt-60 results in increased activity of CASP3 protein] CTD PMID:37702290 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO N-acetyltryptophan inhibits the reaction [Cobalt-60 results in increased activity of CASP9 protein] CTD PMID:37702290 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO N-acetyltryptophan inhibits the reaction [Cobalt-60 results in decreased activity of CAT protein] CTD PMID:37702290 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO N-acetyltryptophan inhibits the reaction [Cobalt-60 results in increased activity of XDH protein] CTD PMID:37702290 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        pharmaceutical 19525
          drug 19525
            nutraceutical 13373
              L-tryptophan 21
                L-tryptophan derivative 9
                  (2S)-2-acetamido-3-(1H-indol-3-yl)propanamide 0
                  1'-glycosyl-L-tryptophan 0
                  1-nitroso-L-tryptophan 0
                  2'-alpha-mannosyl-L-tryptophan 0
                  2-hydroxy-L-tryptophan 0
                  2-methyl-L-tryptophan 0
                  3'-L-tryptophyl-AMP 0
                  4-(3-methylbut-2-enyl)-L-abrine 0
                  4-(3-methylbut-2-enyl)-L-tryptophan 0
                  4-hydroxy-L-tryptophan 0
                  5-chloro-L-tryptophan 0
                  5-methoxytryptophan 0
                  6,7-dichloro-L-tryptophan 0
                  6-chloro-L-tryptophan 0
                  7-(3-methylbut-2-enyl)-L-tryptophan 0
                  7-chloro-L-tryptophan 0
                  7-hydroxy-L-tryptophan + 0
                  L-6'-bromotryptophan + 0
                  L-tryptophan 2-naphthylamide 0
                  N(alpha)-methyl-L-tryptophan 0
                  N-(fatty acyl)-L-tryptophan(1-) + 0
                  N-\{[4-(4-phenylpiperidin-1-yl)phenyl]sulfonyl\}-L-tryptophan 0
                  N-acetyl-L-tryptophan 6
                  N2-succinyl-L-tryptophan 0
                  SID 26681509 0
                  cysteine tryptophylquinone + 0
                  dihydroxy-L-tryptophan + 0
                  hydroxy-L-tryptophan + 0
                  hypaphorine 0
                  ilomastat 3
                  tryptophan N-glucoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    main group molecular entity 19811
                      s-block molecular entity 19647
                        hydrogen molecular entity 19628
                          hydrides 19139
                            inorganic hydride 18156
                              pnictogen hydride 18146
                                nitrogen hydride 18059
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17865
                                        amino acid 16057
                                          alpha-amino acid 13932
                                            L-alpha-amino acid 12141
                                              erythrose 4-phosphate/phosphoenolpyruvate family amino acid 2403
                                                L-tryptophan 21
                                                  L-tryptophan derivative 9
                                                    (2S)-2-acetamido-3-(1H-indol-3-yl)propanamide 0
                                                    1'-glycosyl-L-tryptophan 0
                                                    1-nitroso-L-tryptophan 0
                                                    2'-alpha-mannosyl-L-tryptophan 0
                                                    2-hydroxy-L-tryptophan 0
                                                    2-methyl-L-tryptophan 0
                                                    3'-L-tryptophyl-AMP 0
                                                    4-(3-methylbut-2-enyl)-L-abrine 0
                                                    4-(3-methylbut-2-enyl)-L-tryptophan 0
                                                    4-hydroxy-L-tryptophan 0
                                                    5-chloro-L-tryptophan 0
                                                    5-methoxytryptophan 0
                                                    6,7-dichloro-L-tryptophan 0
                                                    6-chloro-L-tryptophan 0
                                                    7-(3-methylbut-2-enyl)-L-tryptophan 0
                                                    7-chloro-L-tryptophan 0
                                                    7-hydroxy-L-tryptophan + 0
                                                    L-6'-bromotryptophan + 0
                                                    L-tryptophan 2-naphthylamide 0
                                                    N(alpha)-methyl-L-tryptophan 0
                                                    N-(fatty acyl)-L-tryptophan(1-) + 0
                                                    N-\{[4-(4-phenylpiperidin-1-yl)phenyl]sulfonyl\}-L-tryptophan 0
                                                    N-acetyl-L-tryptophan 6
                                                    N2-succinyl-L-tryptophan 0
                                                    SID 26681509 0
                                                    cysteine tryptophylquinone + 0
                                                    dihydroxy-L-tryptophan + 0
                                                    hydroxy-L-tryptophan + 0
                                                    hypaphorine 0
                                                    ilomastat 3
                                                    tryptophan N-glucoside 0
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