sulforaphane - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	sulforaphane	go back to main search page
Accession:	CHEBI:47807	browse the term
Definition:	An isothiocyanate having a 4-(methylsulfinyl)butyl group attached to the nitrogen.
Synonyms:	exact_synonym:	4-isothiocyanatobutyl methyl sulfoxide
	related_synonym:	1-Isothiocyanato-4-(methylsulfinyl)butane; Formula=C6H11NOS2; InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3; InChIKey=SUVMJBTUFCVSAD-UHFFFAOYSA-N; SMILES=N(=C=S)CCCCS(=O)C; Sulforafan
	xref:	CAS:4478-93-7; HMDB:HMDB0005792; LINCS:LSM-4919
	xref_mesh:	MESH:C016766
	xref:	PMID:16442570; PMID:17134937; PMID:18090122; Patent:CA2839972; Patent:CN103229711; Patent:US2013323225; Patent:WO2013179056; Patent:WO2013179057; Reaxys:1723237; Wikipedia:Sulforaphane

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Genes (1833)

sulforaphane

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 6430548M08 gene like

decreases expression

sulforaphane results in decreased expression of KIAA0513 mRNA

NCBI chr19:48,168,651...48,216,571
Ensembl chr19:48,198,209...48,216,575

G

APOBEC1 complementation factor

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of A1CF mRNA

NCBI chr 1:229,736,037...229,823,499
Ensembl chr 1:229,736,106...229,824,354

G

alpha-2-macroglobulin

decreases expression

sulforaphane results in decreased expression of A2M mRNA

NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786

G

alpha 1,4-galactosyltransferase

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of A4GALT mRNA

NCBI chr 7:114,368,525...114,392,872
Ensembl chr 7:114,368,276...114,396,071

G

aminoadipate-semialdehyde synthase

decreases expression

sulforaphane results in decreased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

apoptosis-associated tyrosine kinase

decreases expression

sulforaphane results in decreased expression of AATK mRNA

NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112

G

ATP binding cassette subfamily A member 1

multiple interactions

sulforaphane inhibits the reaction [fenamidone results in increased expression of ABCA1 mRNA]

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 7

decreases expression

sulforaphane results in decreased expression of ABCA7 mRNA

NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425

G

ATP binding cassette subfamily B member 10

decreases expression

sulforaphane results in decreased expression of ABCB10 mRNA

NCBI chr19:51,952,655...51,982,910
Ensembl chr19:51,952,681...51,982,753

G

ATP binding cassette subfamily B member 1A

multiple interactions
decreases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ABCB1A mRNA; sulforaphane inhibits the reaction [Genistein results in increased expression of ABCB1A mRNA]
sulforaphane inhibits the reaction [ginkgolide B results in increased expression of ABCB1 mRNA]
sulforaphane results in decreased expression of ABCB1 mRNA

PMID:25450479 PMID:26775663 PMID:32185415

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily B member 6

increases expression

sulforaphane results in increased expression of ABCB6 mRNA

NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924

G

ATP binding cassette subfamily C member 1

multiple interactions
increases expression

NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of ABCC1 mRNA]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane results in increased expression of and results in increased activity of ABCC1 protein]; sulforaphane results in increased expression of and results in increased activity of ABCC1 protein

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily C member 2

increases expression

sulforaphane results in increased expression of ABCC2 mRNA; sulforaphane results in increased expression of ABCC2 protein

PMID:11264000 PMID:15896333 PMID:25841332 PMID:31838189 PMID:34767876

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

sulforaphane results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

increases expression

sulforaphane results in increased expression of ABCC4 mRNA; sulforaphane results in increased expression of ABCC4 protein

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily G member 5

decreases expression

sulforaphane results in decreased expression of ABCG5 mRNA

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

abhydrolase domain containing 3, phospholipase

increases expression

sulforaphane results in increased expression of ABHD3 mRNA

NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428

G

abhydrolase domain containing 4, N-acyl phospholipase B

increases expression

sulforaphane results in increased expression of ABHD4 mRNA

PMID:26833863 PMID:31838189

NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966

G

actin binding LIM protein family, member 2

decreases expression

sulforaphane results in decreased expression of ABLIM2 mRNA

NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334

G

actin binding LIM protein family, member 3

increases expression

sulforaphane results in increased expression of ABLIM3 mRNA

NCBI chr18:55,256,135...55,376,629
Ensembl chr18:55,257,583...55,376,380

G

acetyl-CoA acyltransferase 2

increases expression

sulforaphane results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acyl-CoA dehydrogenase, long chain

increases expression

sulforaphane results in increased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase medium chain

increases expression

sulforaphane results in increased expression of ACADM mRNA

NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147

G

acyl-CoA dehydrogenase, very long chain

increases expression

sulforaphane results in increased expression of ACADVL mRNA

NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075

G

acyl-CoA binding domain containing 4

decreases expression

sulforaphane results in decreased expression of ACBD4 mRNA

NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500

G

alkaline ceramidase 2

decreases expression

sulforaphane results in decreased expression of ACER2 mRNA

NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614

G

atypical chemokine receptor 1

increases expression

sulforaphane results in increased expression of DARC mRNA

NCBI chr13:85,782,396...85,784,015
Ensembl chr13:85,782,398...85,783,983

G

atypical chemokine receptor 2

decreases expression

sulforaphane results in decreased expression of ACKR2 mRNA

NCBI chr 8:121,559,563...121,573,633
Ensembl chr 8:121,561,211...121,573,582

G

ATP citrate lyase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

aconitase 2

increases expression

sulforaphane results in increased expression of ACO2 mRNA

NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261

G

acyl-CoA thioesterase 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACOT1 mRNA

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ACOT2 mRNA

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA thioesterase 4

decreases expression

sulforaphane results in decreased expression of ACOT4 mRNA

NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917

G

acid phosphatase 5, tartrate resistant

increases expression

sulforaphane results in increased expression of ACP5 mRNA

NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929

G

acyl-CoA synthetase family member 2

decreases expression

sulforaphane results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression

sulforaphane results in increased expression of ACSL1 mRNA

PMID:26833863 PMID:30529165 PMID:31838189

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase medium-chain family member 3

decreases expression

sulforaphane results in decreased expression of ACSM3 mRNA

NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184

G

actin alpha 2, smooth muscle

affects binding
multiple interactions

ACTA2 protein binds to sulforaphane
sulforaphane inhibits the reaction [fenamidone results in increased expression of ACTA2 mRNA]

PMID:21838287 PMID:27029645

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

actin, beta

affects binding

ACTB protein binds to sulforaphane

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin, alpha, cardiac muscle 1

increases expression
decreases expression

sulforaphane results in increased expression of ACTC1 mRNA
sulforaphane results in decreased expression of ACTC1 mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523

G

actin gamma 2, smooth muscle

increases expression

sulforaphane results in increased expression of ACTG2 mRNA

NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465

G

actin related protein 1A

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ACTR1A mRNA

NCBI chr 1:245,237,821...245,256,618
Ensembl chr 1:245,237,826...245,256,495

G

adenosine deaminase

decreases expression

sulforaphane results in decreased expression of ADA mRNA

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 17

increases expression

sulforaphane results in increased expression of ADAM17 mRNA

NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639

G

ADAM metallopeptidase domain 19

decreases expression
multiple interactions

sulforaphane results in decreased expression of ADAM19 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAM19 mRNA

NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105

G

ADAM metallopeptidase domain 21

increases expression

sulforaphane results in increased expression of ADAM21 mRNA

NCBI chr16:36,625,324...36,627,657
Ensembl chr16:36,618,860...36,628,008

G

ADAM metallopeptidase domain 22

decreases expression

sulforaphane results in decreased expression of ADAM22 mRNA

NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962

G

ADAM metallopeptidase domain 33

decreases expression

sulforaphane results in decreased expression of ADAM33 mRNA

NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461

G

ADAM metallopeptidase domain 8

increases expression

sulforaphane results in increased expression of ADAM8 mRNA

NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801

G

ADAM metallopeptidase with thrombospondin type 1 motif, 15

multiple interactions
decreases expression

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADAMTS15 mRNA
sulforaphane results in decreased expression of ADAMTS15 mRNA

PMID:30529165 PMID:31838189

NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

decreases expression

sulforaphane results in decreased expression of ADAMTS5 mRNA

NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205

G

ADAM metallopeptidase with thrombospondin type 1 motif, 6

decreases expression

sulforaphane results in decreased expression of ADAMTS6 mRNA

NCBI chr 2:35,421,483...35,633,305
Ensembl chr 2:35,421,510...35,633,298

G

ADAMTS-like 4

decreases expression

sulforaphane results in decreased expression of ADAMTSL4 mRNA

NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848

G

adenylate cyclase 7

decreases expression

sulforaphane results in decreased expression of ADCY7 mRNA

NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311

G

adenylate cyclase 8

decreases expression

sulforaphane results in decreased expression of ADCY8 mRNA

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor A2

decreases expression

sulforaphane results in decreased expression of ADGRA2 mRNA

NCBI chr16:64,932,964...64,971,433
Ensembl chr16:64,933,315...64,971,483

G

adhesion G protein-coupled receptor D1

decreases expression

sulforaphane results in decreased expression of ADGRD1 mRNA

NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696

G

adhesion G protein-coupled receptor E4

increases expression

sulforaphane results in increased expression of ADGRE4P mRNA

NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760

G

adhesion G protein-coupled receptor E5

increases expression

sulforaphane results in increased expression of ADGRE5 mRNA

NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638

G

adhesion G protein-coupled receptor G1

decreases expression

sulforaphane results in decreased expression of ADGRG1 mRNA

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G3

increases expression

sulforaphane results in increased expression of ADGRG3 mRNA

NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123

G

adhesion G protein-coupled receptor L1

decreases expression

sulforaphane results in decreased expression of ADGRL1 mRNA

NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139

G

adhesion G protein-coupled receptor L3

decreases expression

sulforaphane results in decreased expression of ADGRL3 mRNA

NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of ADH7 mRNA

NCBI chr 2:226,748,724...226,763,183
Ensembl chr 2:226,741,788...226,763,182

G

adipogenin

increases expression

sulforaphane results in increased expression of ADIG mRNA

NCBI chr 3:147,155,079...147,160,412
Ensembl chr 3:147,154,097...147,160,490
Ensembl chr 3:147,154,097...147,160,490

G

adiponectin, C1Q and collagen domain containing

increases expression

sulforaphane results in increased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adrenomedullin

increases expression

sulforaphane results in increased expression of ADM mRNA

NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654

G

activity-dependent neuroprotector homeobox

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ADNP mRNA

NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312

G

adenosine A2a receptor

increases expression

sulforaphane results in increased expression of ADORA2A mRNA

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

adenosine A2B receptor

increases expression

sulforaphane results in increased expression of ADORA2B mRNA

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

adenosine A3 receptor

increases expression

sulforaphane results in increased expression of ADORA3 mRNA

NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357

G

adrenoceptor beta 1

decreases expression
increases expression

sulforaphane results in decreased expression of ADRB1 mRNA
sulforaphane results in increased expression of ADRB1 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259

G

ArfGAP with FG repeats 2

decreases expression

sulforaphane results in decreased expression of AGFG2 mRNA

NCBI chr12:19,012,228...19,048,433
Ensembl chr12:19,012,258...19,048,421

G

anterior gradient 3, protein disulphide isomerase family member

increases expression

sulforaphane results in increased expression of AGR3 mRNA

NCBI chr 6:52,643,391...52,666,638
Ensembl chr 6:52,643,391...52,666,638

G

angiotensinogen

multiple interactions

NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein modified form]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of NQO1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of NPPA protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of TNF protein]

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor-associated protein

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of AGTRAP mRNA

NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036

G

aryl hydrocarbon receptor

multiple interactions
affects binding

AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]; AHR mutant form inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]]; sulforaphane affects the reaction [anthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [1,2,5,6-dibenzanthracene affects the localization of AHR protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene affects the localization of AHR protein]
sulforaphane binds to AHR protein
[sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein]] promotes the reaction [sulforaphane analog binds to AHR protein]; sulforaphane analog inhibits the reaction [Benzo(a)pyrene binds to AHR protein]
sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of AHR protein]

PMID:19202560 PMID:19362136 PMID:21177068 PMID:22643862 PMID:23566952 More...

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

apoptosis inducing factor, mitochondria associated 1

increases expression

sulforaphane results in increased expression of AIFM1 protein

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

adenylate kinase 6

increases expression

sulforaphane results in increased expression of AK6 mRNA

NCBI chr 2:31,794,316...31,806,375
Ensembl chr 2:31,794,519...31,806,371
Ensembl chr20:31,794,519...31,806,371

G

adenylate kinase 9

increases expression

sulforaphane results in increased expression of AK9 mRNA

NCBI chr20:44,724,494...44,941,135
Ensembl chr20:44,724,496...44,941,136

G

A-kinase anchoring protein 5

decreases expression

sulforaphane results in decreased expression of AKAP5 mRNA

NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578

G

akirin 2

increases expression

sulforaphane results in increased expression of AKIRIN2 mRNA

NCBI chr 5:49,108,231...49,122,566
Ensembl chr 5:49,108,220...49,122,568

G

aldo-keto reductase family 1 member B10

increases expression

sulforaphane results in increased expression of AKR1B10 mRNA

PMID:24383545 PMID:31518892 PMID:31838189

NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852

G

aldo-keto reductase family 1, member C1

increases expression
multiple interactions

sulforaphane results in increased expression of AKR1C1 mRNA
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AKR1C1 mRNA]

PMID:24383545 PMID:25841332 PMID:31518892 PMID:31746589

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

sulforaphane results in increased expression of AKR1C2 mRNA

PMID:24383545 PMID:31746589

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

aldo-keto reductase family 1, member C3

increases expression

sulforaphane results in increased expression of AKR1C3 mRNA; sulforaphane results in increased expression of AKR1C3 protein

PMID:24383545 PMID:31746589

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 1

multiple interactions
decreases expression
increases phosphorylation
decreases phosphorylation

NGF protein inhibits the reaction [sulforaphane results in decreased phosphorylation of AKT1 protein]; sulforaphane results in increased phosphorylation of and results in increased activity of AKT1 protein
sulforaphane results in decreased expression of AKT mRNA
sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT mRNA]; sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of AKT protein]
sulforaphane results in increased phosphorylation of AKT1 protein
[dibenzoylmethane co-treated with sulforaphane] results in decreased phosphorylation of AKT1 protein

PMID:15896333 PMID:17942926 PMID:29407470 PMID:30965051 PMID:37906532

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

albumin

multiple interactions

sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CDK6 protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IFNG protein]; sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased secretion of IL6 protein]; sulforaphane inhibits the reaction [[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene]

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

activated leukocyte cell adhesion molecule

decreases expression

sulforaphane results in decreased expression of ALCAM mRNA

NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954

G

aldehyde dehydrogenase 1 family, member A1

multiple interactions
affects binding
decreases expression

sulforaphane promotes the reaction [Gemcitabine results in decreased expression of ALDH1A1 protein]
ALDH1A1 protein binds to sulforaphane
sulforaphane results in decreased expression of ALDH1A1 protein

PMID:20940707 PMID:21838287

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

aldehyde dehydrogenase 1 family, member A3

decreases expression

sulforaphane results in decreased expression of ALDH1A3 mRNA

NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436

G

aldehyde dehydrogenase 1 family, member L2

decreases expression

sulforaphane results in decreased expression of ALDH1L2 mRNA

NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776

G

aldehyde dehydrogenase 2 family member

increases expression
multiple interactions

sulforaphane results in increased expression of ALDH2 mRNA; sulforaphane results in increased expression of ALDH2 protein
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of ALDH2 protein]

PMID:31838189 PMID:35227738

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

aldehyde dehydrogenase 3 family, member A2

increases expression

sulforaphane results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

sulforaphane results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

arachidonate 5-lipoxygenase activating protein

increases expression

sulforaphane results in increased expression of ALOX5AP mRNA

NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986

G

alkaline phosphatase, germ cell

decreases expression

sulforaphane results in decreased expression of ALPG mRNA

NCBI chr 9:87,748,721...87,761,500
Ensembl chr 9:87,753,648...87,757,836

G

alkaline phosphatase, intestinal

decreases expression

sulforaphane results in decreased expression of ALPI mRNA

NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877

G

alkaline phosphatase, placental

increases expression
decreases expression

sulforaphane results in increased expression of ALPP mRNA
sulforaphane results in decreased expression of ALPP mRNA

PMID:26833863 PMID:31838189

NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606

G

anti-Mullerian hormone

increases expression

sulforaphane results in increased expression of AMH mRNA

NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282

G

angiomotin-like 1

decreases expression

sulforaphane results in decreased expression of AMOTL1 mRNA

NCBI chr 8:11,348,651...11,467,564
Ensembl chr 8:11,353,674...11,467,573

G

anaphase promoting complex subunit 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ANAPC4 mRNA

NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770

G

angiogenin

decreases expression

sulforaphane results in decreased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

angiopoietin-like 4

increases expression

sulforaphane results in increased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin 2

increases expression

sulforaphane results in increased expression of ANK2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

sulforaphane results in decreased expression of ANKH mRNA

NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187

G

ankyrin repeat and KH domain containing 1

increases methylation

sulforaphane results in increased methylation of ANKHD1 gene

NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024

G

ankyrin repeat domain 2

decreases expression

sulforaphane results in decreased expression of ANKRD2 mRNA

NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566

G

ankyrin repeat domain 22

increases expression

sulforaphane results in increased expression of ANKRD22 mRNA

NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381

G

ankyrin repeat domain 29

decreases expression

sulforaphane results in decreased expression of ANKRD29 mRNA

NCBI chr18:3,436,301...3,494,292
Ensembl chr18:3,436,303...3,494,296

G

ankyrin repeat domain 49

decreases expression

sulforaphane results in decreased expression of ANKRD49 mRNA

NCBI chr 8:11,627,512...11,632,200
Ensembl chr 8:11,627,518...11,632,207

G

anoctamin 2

decreases expression

sulforaphane results in decreased expression of ANO2 mRNA

NCBI chr 4:158,514,200...158,855,639
Ensembl chr 4:158,496,014...158,855,651

G

anoctamin 9

decreases expression

sulforaphane results in decreased expression of ANO9 mRNA

NCBI chr 1:196,208,863...196,230,381
Ensembl chr 1:196,197,341...196,229,900

G

adenine nucleotide translocase lysine methyltransferase

decreases expression

sulforaphane results in decreased expression of ANTKMT mRNA

NCBI chr10:14,812,274...14,814,798
Ensembl chr10:14,812,269...14,814,193

G

ANTXR cell adhesion molecule 2

increases expression

sulforaphane results in increased expression of ANTXR2 mRNA

NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094

G

annexin A1

increases expression

sulforaphane results in increased expression of ANXA1 mRNA

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

G

annexin A8

increases expression
decreases expression

sulforaphane results in increased expression of ANXA8 mRNA
sulforaphane results in decreased expression of ANXA8 mRNA

PMID:30529165 PMID:31838189

NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043

G

amine oxidase, copper containing 2, pseudogene 1

increases expression

sulforaphane results in increased expression of AOC2 mRNA

NCBI chr10:86,267,007...86,268,473

G

adaptor related protein complex 3 subunit mu 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of AP3M1 mRNA

NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844

G

amyloid beta precursor protein binding family B member 1 interacting protein

decreases expression

sulforaphane results in decreased expression of APBB1IP mRNA

NCBI chr17:84,941,404...85,033,020
Ensembl chr17:84,982,243...85,033,010

G

APC down-regulated 1

decreases expression

sulforaphane results in decreased expression of APCDD1 mRNA

NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070

G

amyloid beta precursor like protein 1

decreases expression

sulforaphane results in decreased expression of APLP1 mRNA

NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155

G

apolipoprotein L7a like 1

increases expression

sulforaphane results in increased expression of APOL7A mRNA

NCBI chr 7:109,118,559...109,149,798
Ensembl chr 7:109,131,064...109,147,649

G

apolipoprotein O

increases expression

sulforaphane results in increased expression of APOO mRNA

NCBI chr X:59,157,971...59,262,940
Ensembl chr X:59,158,049...59,262,940

G

aquaporin 3 (Gill blood group)

decreases expression

sulforaphane results in decreased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 4

increases expression

sulforaphane results in increased expression of AQP4 mRNA

NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856

G

androgen receptor

multiple interactions
increases expression

benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulforaphane results in decreased expression of AR protein]; HDAC6 protein inhibits the reaction [sulforaphane results in decreased expression of AR protein]; NFE2L2 protein affects the reaction [sulforaphane results in increased expression of AR protein]; sulforaphane inhibits the reaction [AR protein binds to ERG enhancer]; sulforaphane inhibits the reaction [AR protein binds to KLK3 enhancer]; sulforaphane inhibits the reaction [HSP90AA1 protein binds to AR protein]; sulforaphane results in increased degradation of and results in decreased expression of and results in decreased activity of AR protein

PMID:19805354 PMID:35227738

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

amphiregulin

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of AREG mRNA

NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535

G

ARFGEF family member 3

decreases expression

sulforaphane results in decreased expression of ARFGEF3 mRNA

NCBI chr 1:13,245,578...13,404,319
Ensembl chr 1:13,244,830...13,404,084

G

arginase 2

decreases expression

sulforaphane results in decreased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 20

decreases expression

sulforaphane results in decreased expression of ARHGAP20 mRNA

NCBI chr 8:52,074,472...52,155,739
Ensembl chr 8:52,074,158...52,155,739

G

Rho GTPase activating protein 26

increases expression

sulforaphane results in increased expression of ARHGAP26 mRNA

NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194

G

Rho GTPase activating protein 28

decreases expression

sulforaphane results in decreased expression of ARHGAP28 mRNA

NCBI chr 9:107,832,584...107,998,030
Ensembl chr 9:107,833,330...107,998,000

G

Rho GTPase activating protein 31

decreases expression

sulforaphane results in decreased expression of ARHGAP31 mRNA

NCBI chr11:62,038,635...62,151,564
Ensembl chr11:62,038,635...62,151,564

G

Rho GDP dissociation inhibitor beta

decreases expression

sulforaphane results in decreased expression of ARHGDIB mRNA

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

Rho guanine nucleotide exchange factor 10 like

increases expression

sulforaphane results in increased expression of ARHGEF10L mRNA

NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538

G

Rho guanine nucleotide exchange factor 26

decreases expression

sulforaphane results in decreased expression of ARHGEF26 mRNA

NCBI chr 2:146,740,336...146,850,918
Ensembl chr 2:146,739,631...146,850,819

G

Rho guanine nucleotide exchange factor 39

increases expression

sulforaphane results in increased expression of ARHGEF39 mRNA

NCBI chr 5:57,752,509...57,756,079
Ensembl chr 5:57,752,509...57,756,109

G

Cdc42 guanine nucleotide exchange factor 9

decreases expression

sulforaphane results in decreased expression of ARHGEF9 mRNA

NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513

G

AT-rich interaction domain 3A

increases expression

sulforaphane results in increased expression of ARID3A mRNA

NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599

G

AT-rich interaction domain 5B

decreases expression

sulforaphane results in decreased expression of ARID5B mRNA

NCBI chr20:20,307,731...20,490,746
Ensembl chr20:20,307,731...20,487,433

G

arylsulfatase family, member J

increases expression

sulforaphane results in increased expression of ARSJ mRNA

NCBI chr 2:214,774,631...214,854,614
Ensembl chr 2:214,774,654...214,854,612

G

ADP-ribosyltransferase 3

increases expression

sulforaphane results in increased expression of ART3 mRNA

NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407

G

ankyrin repeat and SOCS box-containing 2

increases expression

sulforaphane results in increased expression of ASB2 mRNA

NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854

G

ankyrin repeat and SOCS box-containing 9

decreases expression

sulforaphane results in decreased expression of ASB9 mRNA

NCBI chr X:29,956,576...30,001,436
Ensembl chr X:29,956,576...30,001,105

G

anti-silencing function 1A histone chaperone

increases expression

sulforaphane results in increased expression of ASF1A mRNA

NCBI chr20:32,893,962...32,908,808
Ensembl chr20:32,893,573...32,908,808

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

sulforaphane results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

aspartate-beta-hydroxylase

increases expression

sulforaphane results in increased expression of ASPH mRNA

NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876

G

asporin

decreases expression

sulforaphane results in decreased expression of ASPN mRNA

NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041

G

argininosuccinate synthase 1

decreases expression

sulforaphane results in decreased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

activating transcription factor 4

multiple interactions
increases expression

sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
sulforaphane results in increased expression of ATF4 protein

PMID:24967692 PMID:37385402

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

autophagy related 12

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATG12 mRNA

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

atonal bHLH transcription factor 8

decreases expression

sulforaphane results in decreased expression of ATOH8 mRNA

NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168

G

ATPase cation transporting 13A2

increases expression

sulforaphane results in increased expression of ATP13A2 mRNA

NCBI chr 5:153,292,722...153,312,143
Ensembl chr 5:153,292,751...153,312,139

G

ATPase Na+/K+ transporting subunit alpha 3

decreases expression

sulforaphane results in decreased expression of ATP1A3 mRNA

NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases expression

sulforaphane results in increased expression of ATP2A2 mRNA

NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101

G

ATPase plasma membrane Ca2+ transporting 4

decreases expression

sulforaphane results in decreased expression of ATP2B4 mRNA

NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246

G

ATP synthase F1 subunit beta

affects binding

ATP5F1B protein binds to sulforaphane

NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273

G

ATP synthase membrane subunit c locus 1

increases expression

sulforaphane results in increased expression of ATP5MC1 mRNA

NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124

G

ATP synthase membrane subunit e

increases expression

sulforaphane results in increased expression of ATP5ME mRNA

NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013

G

ATPase H+ transporting V0 subunit D2

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ATP6V0D2 mRNA
sulforaphane results in decreased expression of ATP6V0D2 mRNA

NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354

G

ataxin 10

decreases expression

sulforaphane results in decreased expression of ATXN10 mRNA

NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087

G

aurora kinase A

increases expression

sulforaphane results in increased expression of AURKA mRNA

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

Beta-1,3-galactosyltransferase 4

decreases expression

sulforaphane results in decreased expression of B3GALT4 mRNA

NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315

G

beta-1,3-glucuronyltransferase 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of B3GAT3 mRNA

NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

increases expression

sulforaphane results in increased expression of B3GNT5 mRNA

NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

increases expression

sulforaphane results in increased expression of B4GALNT1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190

G

beta-1,4-galactosyltransferase 1

increases expression

sulforaphane results in increased expression of B4GALT1 mRNA

NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461

G

beta-1,4-galactosyltransferase 6

increases expression

sulforaphane results in increased expression of B4GALT6 mRNA

NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247

G

BTB domain and CNC homolog 1

increases expression

sulforaphane results in increased expression of BACH1 mRNA; sulforaphane results in increased expression of BACH1 protein

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

BCL2-associated agonist of cell death

decreases expression

sulforaphane results in decreased expression of BAD mRNA

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BAG cochaperone 1

decreases expression

sulforaphane results in decreased expression of BAG1 mRNA

NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075

G

BAG cochaperone 3

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BAG3 mRNA
sulforaphane results in increased expression of BAG3 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

Btg3 associated nuclear protein

decreases expression

sulforaphane results in decreased expression of BANP mRNA

NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738

G

BRCA1 associated deubiquitinase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BAP1 mRNA

NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535

G

brain abundant, membrane attached signal protein 1

increases expression

sulforaphane results in increased expression of BASP1 mRNA

NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043

G

basic leucine zipper ATF-like transcription factor 3

increases expression

sulforaphane results in increased expression of BATF3 mRNA

NCBI chr13:102,689,657...102,701,241
Ensembl chr13:102,689,657...102,701,139

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

sulforaphane results in increased expression of BAX protein
sulforaphane results in increased expression of BAX mRNA; sulforaphane results in increased expression of BAX protein
sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]

PMID:17942926 PMID:24967692 PMID:26833863 PMID:27878984 PMID:27993529

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

multiple interactions
increases expression

sulforaphane inhibits the reaction [ochratoxin A results in increased expression of BBC3 mRNA]
sulforaphane results in increased expression of BBC3 mRNA; sulforaphane results in increased expression of BBC3 protein

PMID:27878984 PMID:28710020 PMID:35724838

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

basal cell adhesion molecule (Lutheran blood group)

decreases expression

sulforaphane results in decreased expression of BCAM mRNA

NCBI chr 1:79,415,016...79,429,403
Ensembl chr 1:79,415,017...79,429,403

G

butyrylcholinesterase

increases expression

sulforaphane results in increased expression of BCHE mRNA

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

branched chain keto acid dehydrogenase E1 subunit alpha

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BCKDHA mRNA

NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862

G

BCL10, immune signaling adaptor

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BCL10 mRNA

NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523

G

BCL2, apoptosis regulator

multiple interactions
decreases expression
increases expression

[Eugenol results in increased activity of sulforaphane] which results in decreased expression of BCL2; [sulforaphane results in increased activity of Eugenol] which results in decreased expression of BCL2
sulforaphane results in decreased expression of BCL2 mRNA; sulforaphane results in decreased expression of BCL2 protein
sulforaphane results in increased expression of BCL2 mRNA; sulforaphane results in increased expression of BCL2 protein
sulforaphane inhibits the reaction [Ethanol results in decreased expression of BCL2 mRNA]; sulforaphane inhibits the reaction [Ethanol results in decreased expression of BCL2 protein]

PMID:21382956 PMID:27878984 PMID:29069573

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL2-related protein A1

increases expression

sulforaphane results in increased expression of BCL2A1 mRNA

NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998

G

Bcl2-like 1

multiple interactions
decreases expression

sulforaphane inhibits the reaction [sulforaphane results in decreased expression of BCL2L1 protein]

PMID:21684301 PMID:26833863

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479

G

BCL3, transcription coactivator

decreases expression

sulforaphane results in decreased expression of BCL3 mRNA

NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607

G

BCL6, transcription repressor

increases expression
decreases expression

sulforaphane results in increased expression of BCL6 mRNA
sulforaphane results in decreased expression of BCL6 mRNA

PMID:26833863 PMID:31838189

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

3-hydroxybutyrate dehydrogenase 1

increases expression

sulforaphane results in increased expression of BDH1 mRNA

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

bradykinin receptor B2

decreases expression

sulforaphane results in decreased expression of BDKRB2 mRNA

NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497

G

brain-derived neurotrophic factor

multiple interactions
decreases expression
increases expression

sulforaphane promotes the reaction [Pyruvaldehyde results in increased expression of BDNF protein]
sulforaphane results in decreased expression of BDNF mRNA
sulforaphane results in increased expression of BDNF protein

PMID:25933243 PMID:31838189

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

G

beclin 1

multiple interactions

sulforaphane inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein]

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

BEN domain containing 6

increases expression

sulforaphane results in increased expression of BEND6 mRNA

NCBI chr 9:36,081,033...36,135,309
Ensembl chr 9:36,081,484...36,135,228

G

brain expressed, X-linked 4

decreases expression

sulforaphane results in decreased expression of BEX4 mRNA

NCBI chr X:99,131,985...99,133,417
Ensembl chr X:99,131,942...99,133,531

G

basic helix-loop-helix family, member e40

increases expression

sulforaphane results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

BH3 interacting domain death agonist

multiple interactions
increases expression

sulforaphane inhibits the reaction [sulforaphane results in increased expression of BID protein]
[sulforaphane co-treated with TNFSF10 protein] results in increased cleavage of BID protein

PMID:21684301 PMID:26833863 PMID:29792947

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

bridging integrator 2

increases expression

sulforaphane results in increased expression of BIN2 mRNA

NCBI chr 7:131,742,001...131,768,208
Ensembl chr 7:131,742,002...131,786,285

G

baculoviral IAP repeat-containing 3

increases expression

sulforaphane results in increased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

Bcl2 modifying factor

decreases expression

sulforaphane results in decreased expression of BMF mRNA

NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145

G

bone morphogenetic protein 2

decreases expression

sulforaphane results in decreased expression of BMP2 mRNA

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

bone morphogenetic protein 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BMP4 mRNA

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

bora, aurora kinase A activator

increases expression

sulforaphane results in increased expression of BORA mRNA

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

G

BMP/retinoic acid inducible neural specific 3

decreases expression

sulforaphane results in decreased expression of BRINP3 mRNA

NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770

G

BRO1 domain and CAAX motif containing

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BROX mRNA

NCBI chr13:94,920,107...94,940,189
Ensembl chr13:94,920,112...94,940,227

G

BR serine/threonine kinase 2

decreases expression

sulforaphane results in decreased expression of BRSK2 mRNA

NCBI chr 1:197,035,505...197,088,624
Ensembl chr 1:197,035,633...197,088,092

G

bone marrow stromal cell antigen 1

increases expression

sulforaphane results in increased expression of BST1 mRNA

NCBI chr14:67,253,706...67,270,203
Ensembl chr14:67,252,998...67,270,180

G

B-TFIID TATA-box binding protein associated factor 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BTAF1 mRNA

NCBI chr 1:234,653,219...234,743,903
Ensembl chr 1:234,653,156...234,743,903

G

BTG anti-proliferation factor 2

increases expression

sulforaphane results in increased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

butyrophilin-like 9

multiple interactions
increases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of BTNL9 mRNA
sulforaphane results in increased expression of BTNL9 mRNA

NCBI chr10:33,466,059...33,489,229
Ensembl chr10:33,470,536...33,489,025

G

BUB1 mitotic checkpoint serine/threonine kinase

increases expression

sulforaphane results in increased expression of BUB1 mRNA

NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650

G

similar to human chromosome 22 open reading frame 39

decreases expression

sulforaphane results in decreased expression of C22ORF39 mRNA

NCBI chr11:82,155,992...82,160,235
Ensembl chr11:82,159,528...82,160,235

G

similar to human chromosome 1 open reading frame 115

decreases expression

sulforaphane results in decreased expression of C1ORF115 mRNA

NCBI chr13:96,422,308...96,432,044
Ensembl chr13:96,422,302...96,432,068

G

similar to human chromosome 1 open reading frame 53

decreases expression

sulforaphane results in decreased expression of C1ORF53 mRNA

NCBI chr13:50,413,785...50,418,974
Ensembl chr13:50,413,785...50,419,120

G

similar to human chromosome 1 open reading frame 198

decreases expression

sulforaphane results in decreased expression of C1ORF198 mRNA

NCBI chr19:52,604,060...52,629,436
Ensembl chr19:52,604,060...52,629,436

G

similar to human chromosome 11 open reading frame 86

decreases expression

sulforaphane results in decreased expression of C11ORF86 mRNA

NCBI chr 1:201,784,009...201,785,916
Ensembl chr 1:201,784,009...201,785,916

G

complement C1q like 1

decreases expression

sulforaphane results in decreased expression of C1QL1 mRNA

NCBI chr10:87,902,125...87,909,556
Ensembl chr10:87,902,137...87,909,310

G

C1q and TNF related 1

decreases expression

sulforaphane results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 6

decreases expression

sulforaphane results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412

G

complement C1r

decreases expression

sulforaphane results in decreased expression of C1R mRNA

NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484

G

complement C3

increases expression
decreases expression

sulforaphane results in increased expression of C3 mRNA
sulforaphane results in decreased expression of C3 mRNA

PMID:26833863 PMID:31838189

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement C3a receptor 1

increases expression

sulforaphane results in increased expression of C3AR1 mRNA

NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701

G

complement component 4 binding protein, alpha

decreases expression

sulforaphane results in decreased expression of C4BPA mRNA

NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205

G

complement C5

decreases expression

sulforaphane results in decreased expression of HC mRNA

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

chromosome 9 C2orf15 homolog

decreases expression

sulforaphane results in decreased expression of C2ORF15 mRNA

G

similar to human chromosome 6 open reading frame 132

decreases expression

sulforaphane results in decreased expression of C6ORF132 mRNA

NCBI chr 9:13,524,822...13,561,756
Ensembl chr 9:13,525,395...13,561,585

G

calcium binding protein 39-like

increases expression

sulforaphane results in increased expression of CAB39L mRNA

NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545

G

calcium binding tyrosine phosphorylation regulated

increases expression

sulforaphane results in increased expression of CABYR mRNA

NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840

G

calcium voltage-gated channel auxiliary subunit beta 1

decreases expression

sulforaphane results in decreased expression of CACNB1 mRNA

NCBI chr10:82,998,182...83,018,838
Ensembl chr10:82,998,182...83,018,694

G

calcium dependent secretion activator 2

decreases expression

sulforaphane results in decreased expression of CADPS2 mRNA

NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829

G

calcitonin receptor

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CALCR mRNA

NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392

G

calmodulin-like 3

increases expression

sulforaphane results in increased expression of CALML3 mRNA

NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175

G

calcium/calmodulin-dependent protein kinase ID

decreases expression

sulforaphane results in decreased expression of CAMK1D mRNA

NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556

G

calcium/calmodulin-dependent protein kinase II inhibitor 1

decreases expression

sulforaphane results in decreased expression of CAMK2N1 mRNA

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

G

capping actin protein, gelsolin like

increases expression

sulforaphane results in increased expression of CAPG mRNA

NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856

G

calpain, small subunit 1

affects binding

CAPNS1 protein binds to sulforaphane

NCBI chr 1:85,444,613...85,454,861
Ensembl chr 1:85,444,608...85,454,795

G

carbonic anhydrase 3

increases expression

sulforaphane results in increased expression of CAR3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

caspase recruitment domain family, member 19

increases expression

sulforaphane results in increased expression of CARD19 mRNA

NCBI chr17:15,432,632...15,445,317
Ensembl chr17:15,432,612...15,445,318

G

calcium regulated heat stable protein 1

decreases expression

sulforaphane results in decreased expression of CARHSP1 mRNA

NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019

G

capping protein regulator and myosin 1 linker 1

decreases expression

sulforaphane results in decreased expression of CARMIL1 mRNA

NCBI chr17:40,807,921...41,088,326
Ensembl chr17:40,808,389...41,088,326

G

cysteinyl-tRNA synthetase 1

increases expression

sulforaphane results in increased expression of CARS1 mRNA

NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941

G

calcium/calmodulin dependent serine protein kinase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CASK mRNA

NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694

G

caspase 1

multiple interactions

sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CASP1 protein]

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

multiple interactions

sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 3

multiple interactions
increases activity

[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein; [sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP3 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; NGF protein inhibits the reaction [sulforaphane results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Pyruvaldehyde results in increased activity of CASP3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]
[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP3 mRNA]
sulforaphane inhibits the reaction [cyanoginosin LR results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in increased expression of CASP3 protein]; sulforaphane inhibits the reaction [Ethanol results in increased expression of CASP3 protein modified form]; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP3 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]

PMID:19780897 PMID:21684301 PMID:22922937 PMID:23518299 PMID:24967692 More...

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

multiple interactions

[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 7

increases activity

sulforaphane results in increased activity of CASP7 protein

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

multiple interactions
increases expression

[sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP8 protein; sulforaphane results in increased expression of and results in increased activity of CASP8 protein
sulforaphane results in increased expression of CASP8 mRNA

PMID:26833863 PMID:29792947 PMID:31838189

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
decreases expression
increases expression
increases activity

[sulforaphane co-treated with TNFSF10 protein] results in decreased expression of CASP9 protein; sulforaphane inhibits the reaction [Oxidopamine results in increased activity of CASP9 protein]
sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 mRNA]; sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of CASP9 protein]
sulforaphane results in decreased expression of CASP9 mRNA
sulforaphane results in increased expression of CASP9 protein
sulforaphane results in increased activity of CASP9 protein

PMID:19780897 PMID:26833863 PMID:27878984 PMID:29792947 PMID:31838189 More...

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

calsequestrin 2

increases expression

sulforaphane results in increased expression of CASQ2 mRNA

NCBI chr 2:189,526,003...189,582,276
Ensembl chr 2:189,525,960...189,582,267

G

castor zinc finger 1

decreases expression

sulforaphane results in decreased expression of CASZ1 mRNA

NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400

G

catalase

multiple interactions
increases expression
increases activity

sulforaphane inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Cisplatin results in decreased expression of CAT protein]
sulforaphane results in increased expression of CAT mRNA; sulforaphane results in increased expression of CAT protein
sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [AGT protein modified form results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Dinitrochlorobenzene results in decreased expression of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
sulforaphane results in increased activity of CAT protein

PMID:19913604 PMID:22664424 PMID:24967692 PMID:29353218 PMID:29964319 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

Cbl proto-oncogene B

increases expression

sulforaphane results in increased expression of CBLB mRNA

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

G

carbonyl reductase 3

multiple interactions
increases expression

[sulforaphane co-treated with dibenzoylmethane] results in increased expression of CBR3 mRNA
sulforaphane results in increased expression of CBR3 mRNA

PMID:17942926 PMID:20806931 PMID:31838189

NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875

G

chromobox 6

increases expression

sulforaphane results in increased expression of CBX6 mRNA

NCBI chr 7:111,372,979...111,383,026
Ensembl chr 7:111,372,980...111,383,091

G

coiled-coil domain containing 102A

decreases expression

sulforaphane results in decreased expression of CCDC102A mRNA

NCBI chr19:10,102,543...10,118,657
Ensembl chr19:10,103,361...10,118,657

G

coiled-coil domain containing 13

increases expression

sulforaphane results in increased expression of CCDC13 mRNA

NCBI chr 8:121,455,202...121,507,487
Ensembl chr 8:121,457,697...121,502,337

G

coiled-coil domain containing 18

increases expression

sulforaphane results in increased expression of CCDC18 mRNA

NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711

G

coiled-coil domain containing 24

increases expression

sulforaphane results in increased expression of CCDC24 mRNA

NCBI chr 5:131,398,766...131,412,395
Ensembl chr 5:131,408,143...131,412,029

G

coiled coil domain containing 28B

decreases expression

sulforaphane results in decreased expression of CCDC28B mRNA

NCBI chr 5:141,962,275...141,967,278
Ensembl chr 5:141,962,276...141,967,382

G

coiled-coil domain containing 3

decreases expression

sulforaphane results in decreased expression of CCDC3 mRNA

NCBI chr17:73,031,891...73,135,173
Ensembl chr17:73,035,045...73,135,337

G

coiled-coil domain containing 80

increases expression
decreases expression

sulforaphane results in increased expression of CCDC80 mRNA
sulforaphane results in decreased expression of CCDC80 mRNA

PMID:30529165 PMID:31838189

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 11

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL11 mRNA

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 2

multiple interactions
decreases expression
increases expression

sulforaphane inhibits the reaction [Cyclosporine results in increased expression of CCL2 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]
sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CCL2 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CCL2 mRNA]
sulforaphane metabolite results in decreased expression of CCL2 mRNA; sulforaphane results in decreased expression of CCL2 mRNA
sulforaphane results in increased expression of CCL2 mRNA

PMID:23958496 PMID:26833863 PMID:32387680 PMID:35724838

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

increases expression
multiple interactions

sulforaphane results in increased expression of CCL20 mRNA
[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CCL20 mRNA

PMID:26833863 PMID:30529165

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 5

multiple interactions

sulforaphane inhibits the reaction [Cyclosporine results in increased expression of CCL5 mRNA]; sulforaphane inhibits the reaction [Tacrolimus results in increased expression of CCL5 mRNA]

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 2

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of CCN2 protein]; NFE2L2 gene mutant form inhibits the reaction [sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [AGT protein modified form results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Oxygen deficiency results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]

PMID:24707343 PMID:24967692 PMID:29353218 PMID:30096613

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 5

decreases expression

sulforaphane results in decreased expression of CCN5 mRNA

NCBI chr 3:152,491,247...152,502,639
Ensembl chr 3:152,491,220...152,502,636

G

cyclin B1

increases expression

sulforaphane results in increased expression of CCNB1 mRNA; sulforaphane results in increased expression of CCNB1 protein

PMID:15231455 PMID:31838189

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin B2

increases expression

sulforaphane results in increased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

increases expression

sulforaphane results in increased expression of CCND1 protein
sulforaphane results in increased expression of CCND1 mRNA

PMID:17942926 PMID:31838189

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D3

increases expression
multiple interactions

sulforaphane results in increased expression of CCND3 mRNA
sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CCND3 protein]

PMID:26833863 PMID:33007382

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

increases expression

sulforaphane results in increased expression of CCNE1 mRNA

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

decreases expression

sulforaphane results in decreased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

cyclin J

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCNJ mRNA
sulforaphane results in decreased expression of CCNJ mRNA

NCBI chr 1:239,659,588...239,677,367

G

cyclin J-like

increases expression

sulforaphane results in increased expression of CCNJL mRNA

NCBI chr10:27,995,682...28,053,428
Ensembl chr10:27,995,679...28,053,426

G

cyclin Y-like 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCNYL1 mRNA

NCBI chr 9:66,071,721...66,121,742
Ensembl chr 9:66,071,543...66,107,999

G

cell cycle progression 1

increases expression

sulforaphane results in increased expression of CCPG1 mRNA

PMID:26833863 PMID:31838189

NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430

G

C-C motif chemokine receptor 2

decreases expression

sulforaphane results in decreased expression of CCR2 mRNA

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 4

affects methylation

sulforaphane affects the methylation of CCR4 promoter

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

G

chaperonin containing TCP1 subunit 2

affects binding
multiple interactions

CCT2 protein binds to sulforaphane
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCT2 mRNA

PMID:21838287 PMID:30529165

NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944

G

chaperonin containing TCP1 subunit 8

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CCT8 mRNA

NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079

G

CD14 molecule

increases expression

sulforaphane results in increased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD163 molecule

increases expression

sulforaphane results in increased expression of CD163 mRNA

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

CD180 molecule

decreases expression

sulforaphane results in decreased expression of CD180 mRNA

NCBI chr 2:33,855,940...33,870,046
Ensembl chr 2:33,855,991...33,899,936

G

CD22 molecule

increases expression

sulforaphane results in increased expression of CD22 mRNA

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

G

CD24 molecule

decreases expression

sulforaphane results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

Cd300 molecule-like family member F

increases expression

sulforaphane results in increased expression of CD300LF mRNA

NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041

G

Cd68 molecule

increases expression

sulforaphane results in increased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

Cd70 molecule

decreases expression

sulforaphane results in decreased expression of CD70 mRNA

NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715

G

CD74 molecule

decreases expression

sulforaphane results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

Cd82 molecule

decreases expression

sulforaphane results in decreased expression of CD82 mRNA

NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809

G

CD83 molecule

decreases expression

sulforaphane results in decreased expression of CD83 mRNA

NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083

G

CD84 molecule

decreases expression
increases expression

sulforaphane results in decreased expression of CD84 mRNA
sulforaphane results in increased expression of CD84 mRNA

PMID:26833863 PMID:31838189

NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076

G

cytidine deaminase

increases expression
decreases expression

sulforaphane results in increased expression of CDA mRNA
sulforaphane results in decreased expression of CDA mRNA

PMID:26833863 PMID:31838189

NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231

G

cell division cycle 16

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CDC16 mRNA

NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550

G

cell division cycle 20

increases expression

sulforaphane results in increased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

CDC42 binding protein kinase gamma

decreases expression

sulforaphane results in decreased expression of CDC42BPG mRNA

NCBI chr 1:203,608,339...203,628,502
Ensembl chr 1:203,608,574...203,628,502

G

cadherin 1

multiple interactions
increases methylation
decreases expression
increases expression

sulforaphane inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]
sulforaphane results in increased methylation of CDH1 gene
sulforaphane results in decreased expression of CDH1 mRNA
sulforaphane results in increased expression of CDH1

PMID:28624451 PMID:29899271 PMID:31838189

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 10

decreases expression

sulforaphane results in decreased expression of CDH10 mRNA

NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995

G

cadherin 2

increases expression

sulforaphane results in increased expression of CDH2 mRNA

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 5

decreases expression

sulforaphane results in decreased expression of CDH5 mRNA

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cadherin-related family member 4

increases expression

sulforaphane results in increased expression of CDHR4 mRNA

NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367

G

cyclin-dependent kinase 1

increases expression

sulforaphane results in increased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 18

decreases expression

sulforaphane results in decreased expression of CDK18 mRNA

NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525

G

cyclin-dependent kinase 6

multiple interactions

sulforaphane inhibits the reaction [[[ALB protein binds to 4-hydroxy-2-nonenal] which results in increased susceptibility to Trichloroethylene] which results in increased expression of CDK6 protein]

NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634

G

cyclin-dependent kinase-like 4

increases expression

sulforaphane results in increased expression of CDKL4 mRNA

NCBI chr 6:14,449,822...14,492,568
Ensembl chr 6:14,450,681...14,492,046

G

cyclin-dependent kinase inhibitor 1A

increases expression
multiple interactions

sulforaphane results in increased expression of CDKN1A mRNA; sulforaphane results in increased expression of CDKN1A protein
sulforaphane inhibits the reaction [triptolide affects the expression of CDKN1A protein]

PMID:15231455 PMID:17937621 PMID:31838189 PMID:36990132

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1C

decreases expression

sulforaphane results in decreased expression of CDKN1C mRNA

NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048

G

cyclin-dependent kinase inhibitor 2A

multiple interactions
decreases expression

sulforaphane inhibits the reaction [[NFE2L2 protein affects the susceptibility to 1,2-Dimethylhydrazine] which results in increased expression of CDKN2A mRNA]; sulforaphane promotes the reaction [1,2-Dimethylhydrazine results in increased expression of CDKN2A mRNA]; sulforaphane promotes the reaction [1,2-Dimethylhydrazine results in increased expression of CDKN2A protein]
sulforaphane results in decreased expression of CDKN2A mRNA

PMID:26388957 PMID:30529165

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

CDKN2A interacting protein

decreases expression

sulforaphane results in decreased expression of CDKN2AIP mRNA

NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033

G

CDKN2A interacting protein N-terminal like

decreases expression

sulforaphane results in decreased expression of CDKN2AIPNL mRNA

NCBI chr10:36,231,134...36,240,569
Ensembl chr10:36,231,087...36,240,564

G

CCAAT/enhancer binding protein delta

decreases expression

sulforaphane results in decreased expression of CEBPD mRNA

NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829

G

CCAAT/enhancer binding protein epsilon

increases expression

sulforaphane results in increased expression of CEBPE mRNA

NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814

G

centrosomal AT-AC splicing factor

multiple interactions
decreases expression

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CENATAC mRNA
sulforaphane results in decreased expression of CENATAC mRNA

NCBI chr 8:44,735,968...44,742,859
Ensembl chr 8:44,735,972...44,742,837

G

centromere protein I

increases expression

sulforaphane results in increased expression of CENPI mRNA

NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657

G

centromere protein J

increases expression
decreases methylation

sulforaphane results in increased expression of CPAP mRNA
sulforaphane results in decreased methylation of CPAP gene

NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791

G

centrosomal protein 20

increases expression

sulforaphane results in increased expression of CEP20 mRNA

NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837

G

centrosomal protein 55

increases expression

sulforaphane results in increased expression of CEP55 mRNA

NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394

G

centrosomal protein 70

decreases expression

sulforaphane results in decreased expression of CEP70 mRNA

NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855

G

carboxylesterase 1D

multiple interactions
increases expression

NFE2L2 protein affects the reaction [sulforaphane results in increased expression of CES1 mRNA alternative form]; sulforaphane promotes the reaction [[NFE2L2 protein binds to CES1 promoter] which results in increased expression of CES1 mRNA alternative form]; sulforaphane promotes the reaction [NFE2L2 protein binds to CES1 promoter]; sulforaphane results in increased expression of and results in increased activity of CES1 protein alternative form
sulforaphane results in increased expression of CES1 mRNA; sulforaphane results in increased expression of CES1 mRNA alternative form

PMID:19715681 PMID:26833863

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

carboxylesterase 3a

decreases expression

sulforaphane results in decreased expression of CES3 mRNA

NCBI chr19:32,992,386...33,000,562

G

cilia and flagella associated protein 144

increases expression

sulforaphane results in increased expression of CFAP144 mRNA

NCBI chr10:43,509,823...43,519,693
Ensembl chr10:43,509,826...43,520,086

G

cilia and flagella associated protein 251

increases expression

sulforaphane results in increased expression of CFAP251 mRNA

NCBI chr12:33,261,622...33,337,028
Ensembl chr12:33,261,476...33,293,932

G

complement factor D

increases expression

sulforaphane results in increased expression of CFD mRNA

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

G

complement factor properdin

increases expression

sulforaphane results in increased expression of CFP mRNA

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

CF transmembrane conductance regulator

decreases expression

sulforaphane results in decreased expression of CFTR mRNA

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

sulforaphane results in decreased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

chitinase, acidic

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CHIA mRNA

NCBI chr 2:193,614,374...193,656,532
Ensembl chr 2:193,614,114...193,656,533

G

chimerin 1

increases expression

sulforaphane results in increased expression of CHN1 mRNA

NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490

G

cysteine and histidine rich domain containing 1

increases expression

sulforaphane results in increased expression of CHORDC1 mRNA

NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162

G

cholinergic receptor nicotinic beta 1 subunit

decreases expression

sulforaphane results in decreased expression of CHRNB1 mRNA

NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345

G

carbohydrate sulfotransferase 13

decreases expression

sulforaphane results in decreased expression of CHST13 mRNA

NCBI chr 4:122,824,022...122,837,940
Ensembl chr 4:122,824,022...122,838,019

G

carbohydrate sulfotransferase 15

increases expression

sulforaphane results in increased expression of CHST15 mRNA

NCBI chr 1:187,028,860...187,107,908
Ensembl chr 1:187,028,970...187,107,707

G

carbohydrate sulfotransferase 2

decreases expression

sulforaphane results in decreased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

cell death-inducing DFFA-like effector a

increases expression

sulforaphane results in increased expression of CIDEA mRNA

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

cartilage intermediate layer protein 2

increases expression

sulforaphane results in increased expression of CILP2 mRNA

PMID:30529165 PMID:31838189

NCBI chr16:19,539,755...19,547,191
Ensembl chr16:19,539,706...19,547,191

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

decreases expression

sulforaphane results in decreased expression of CITED2 mRNA

NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

decreases expression

sulforaphane results in decreased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

creatine kinase B

decreases expression

sulforaphane results in decreased expression of CKB mRNA

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

CDC28 protein kinase regulatory subunit 2

increases expression

sulforaphane results in increased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

chloride voltage-gated channel 4

increases expression

sulforaphane results in increased expression of CLCN4 mRNA

NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238

G

claudin 4

increases expression

sulforaphane results in increased expression of CLDN4 mRNA

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

claudin 7

decreases expression

sulforaphane results in decreased expression of CLDN7 mRNA

NCBI chr10:54,689,684...54,692,177
Ensembl chr10:54,689,987...54,692,171

G

C-type lectin domain containing 10A

increases expression

sulforaphane results in increased expression of CLEC10A mRNA

NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435

G

C-type lectin domain family 4, member D

increases expression

sulforaphane results in increased expression of CLEC4D mRNA

NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848

G

C-type lectin domain family 4, member E

increases expression

sulforaphane results in increased expression of CLEC4E mRNA

NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767

G

calmegin

increases expression

sulforaphane results in increased expression of CLGN mRNA

NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758

G

chloride intracellular channel 3

decreases expression

sulforaphane results in decreased expression of CLIC3 mRNA

NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018

G

chloride intracellular channel 6

increases expression

sulforaphane results in increased expression of CLIC6 mRNA

NCBI chr11:31,737,813...31,780,360
Ensembl chr11:31,737,813...31,780,061

G

CLPTM1 regulator of GABA type A receptor forward trafficking

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CLPTM1 mRNA

NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092

G

calsyntenin 2

decreases expression

sulforaphane results in decreased expression of CLSTN2 mRNA

NCBI chr 8:98,020,406...98,637,232
Ensembl chr 8:98,021,666...98,637,731

G

clusterin

multiple interactions

[sulforaphane co-treated with dibenzoylmethane] results in decreased expression of CLU mRNA

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

clustered mitochondria homolog

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CLUH mRNA

NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345

G

citramalyl-CoA lyase

increases expression

sulforaphane results in increased expression of CLYBL mRNA

NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695

G

cornifelin

decreases expression

sulforaphane results in decreased expression of CNFN mRNA

NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747

G

cyclic nucleotide gated channel subunit beta 1

decreases expression

sulforaphane results in decreased expression of CNGB1 mRNA

NCBI chr19:9,726,595...9,791,111
Ensembl chr19:9,726,595...9,791,173

G

cornichon family AMPA receptor auxiliary protein 2

increases expression

sulforaphane results in increased expression of CNIH2 mRNA

NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089

G

calponin 1

increases expression

sulforaphane results in increased expression of CNN1 mRNA

NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098

G

calponin 3

decreases expression

sulforaphane results in decreased expression of CNN3 mRNA

NCBI chr 2:209,518,948...209,550,107
Ensembl chr 2:209,518,948...209,550,104

G

CCR4-NOT transcription complex, subunit 6

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CNOT6 mRNA

NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025

G

CCR4-NOT transcription complex subunit 9

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CNOT9 mRNA

NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100

G

cannabinoid receptor 2

multiple interactions

[LEPR protein affects the susceptibility to sulforaphane] which affects the expression of CNR2 protein

NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548

G

contactin associated protein 1

decreases expression

sulforaphane results in decreased expression of CNTNAP1 mRNA

NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611

G

contactin associated protein family member 3

decreases expression

sulforaphane results in decreased expression of CNTNAP3 mRNA

NCBI chr17:267,379...455,478
Ensembl chr17:267,508...454,102

G

cytochrome c oxidase assembly factor 6

increases expression

sulforaphane results in increased expression of COA6 mRNA

NCBI chr19:54,395,746...54,398,348
Ensembl chr19:54,395,742...54,399,407

G

cordon-bleu WH2 repeat protein-like 1

decreases expression

sulforaphane results in decreased expression of COBLL1 mRNA

NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194

G

collagen type I alpha 1 chain

decreases expression

sulforaphane results in decreased expression of COL1A1 mRNA

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type IV alpha 5 chain

increases methylation
decreases expression

sulforaphane results in increased methylation of COL4A5 gene
sulforaphane results in decreased expression of COL4A5 mRNA

NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692

G

collagen type IV alpha 6 chain

decreases expression

sulforaphane results in decreased expression of COL4A6 mRNA

NCBI chr X:104,766,463...105,117,499
Ensembl chr X:104,766,957...105,117,500

G

collagen type V alpha 1 chain

decreases expression
increases methylation

sulforaphane results in decreased expression of COL5A1 mRNA
sulforaphane results in increased methylation of COL5A1 gene

NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588

G

collagen type IX alpha 3 chain

decreases expression

sulforaphane results in decreased expression of COL9A3 mRNA

NCBI chr 3:167,711,776...167,734,468
Ensembl chr 3:167,711,840...167,734,465

G

catechol-O-methyltransferase

multiple interactions

sulforaphane inhibits the reaction [DNMT3B protein binds to COMT promoter]; sulforaphane inhibits the reaction [EP300 protein binds to COMT promoter]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [DNMT3B protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in decreased expression of COMT mRNA]; sulforaphane inhibits the reaction [Estradiol results in increased methylation of COMT promoter]; sulforaphane inhibits the reaction [Genistein promotes the reaction [HDAC1 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Genistein promotes the reaction [MBD2 protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Genistein results in decreased expression of COMT mRNA]; sulforaphane inhibits the reaction [Genistein results in increased methylation of COMT promoter]; sulforaphane inhibits the reaction [HDAC1 protein binds to COMT promoter]

NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642

G

coenzyme Q9

increases expression

sulforaphane results in increased expression of COQ9 mRNA

NCBI chr19:10,166,948...10,179,976
Ensembl chr19:10,166,951...10,179,949

G

corin, serine peptidase

increases expression

sulforaphane results in increased expression of CORIN mRNA

NCBI chr14:35,680,601...35,910,703
Ensembl chr14:35,681,304...35,909,503

G

coronin 6

decreases expression

sulforaphane results in decreased expression of CORO6 mRNA

NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659

G

cytochrome c oxidase subunit 5A

increases expression

sulforaphane results in increased expression of COX5A mRNA

NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781

G

cytochrome c oxidase subunit 5B

increases expression

sulforaphane results in increased expression of COX5B mRNA

NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052

G

cytochrome c oxidase subunit 6A2

increases expression

sulforaphane results in increased expression of COX6A2 mRNA

NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274

G

cytochrome c oxidase subunit 7A1

increases expression

sulforaphane results in increased expression of COX7A1 mRNA

NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151

G

carboxypeptidase A4

decreases expression

sulforaphane results in decreased expression of CPA4 mRNA

NCBI chr 4:59,188,284...59,212,255
Ensembl chr 4:59,188,284...59,212,255

G

carboxypeptidase D

increases expression

sulforaphane results in increased expression of CPD mRNA

NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491

G

cytoplasmic polyadenylation element binding protein 2

decreases methylation

sulforaphane results in decreased methylation of CPEB2 gene

NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743

G

cytoplasmic polyadenylation element binding protein 4

decreases expression

sulforaphane results in decreased expression of CPEB4 mRNA

NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603

G

cadherin-like and PC-esterase domain containing 1

decreases expression

sulforaphane results in decreased expression of CPED1 mRNA

NCBI chr 4:50,516,712...50,789,651
Ensembl chr 4:50,516,819...50,788,674

G

ciliogenesis and planar polarity effector complex subunit 1

decreases expression

sulforaphane results in decreased expression of CPLANE1 mRNA

NCBI chr 2:57,269,195...57,369,580
Ensembl chr 2:57,268,884...57,369,500

G

carboxypeptidase M

decreases expression

sulforaphane results in decreased expression of CPM mRNA

PMID:30529165 PMID:31838189

NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220

G

carbamoyl-phosphate synthase 1

decreases expression

sulforaphane results in decreased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

increases expression

sulforaphane results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

increases expression

sulforaphane results in increased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

complement C3b/C4b receptor 1 like

increases expression

sulforaphane results in increased expression of CR1L mRNA

NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445

G

cellular retinoic acid binding protein 2

decreases expression

sulforaphane results in decreased expression of CRABP2 mRNA

NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379

G

CRACD like

increases expression

sulforaphane results in increased expression of CRACDL mRNA

NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086

G

carnitine O-acetyltransferase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

crumbs cell polarity complex component 3

decreases expression

sulforaphane results in decreased expression of CRB3 mRNA

NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859

G

cAMP responsive element binding protein 5

decreases expression

sulforaphane results in decreased expression of CREB5 mRNA

NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325

G

cellular repressor of E1A-stimulated genes 1

increases expression

sulforaphane results in increased expression of CREG1 mRNA

NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308

G

cysteine-rich protein 2

decreases expression

sulforaphane results in decreased expression of CRIP2 mRNA

NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

sulforaphane results in decreased expression of CRISPLD2 mRNA

NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465

G

CREB regulated transcription coactivator 3

decreases expression

sulforaphane results in decreased expression of CRTC3 mRNA

NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500

G

crystallin, alpha B

decreases expression

sulforaphane results in decreased expression of CRYAB mRNA

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

citrate synthase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CS mRNA

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

G

cold shock domain containing C2

decreases expression

sulforaphane results in decreased expression of CSDC2 mRNA

NCBI chr 7:113,451,998...113,466,464
Ensembl chr 7:113,451,998...113,466,463

G

colony stimulating factor 2

multiple interactions

sulforaphane inhibits the reaction [Vehicle Emissions analog results in increased expression of CSF2 protein]

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

chondroitin sulfate proteoglycan 4

decreases expression

sulforaphane results in decreased expression of CSPG4 mRNA

NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010

G

cysteine and glycine-rich protein 1

decreases expression

sulforaphane results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cysteine and glycine rich protein 3

increases expression

sulforaphane results in increased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cystatin C

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CST3 mRNA

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

CTD nuclear envelope phosphatase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDNEP1 mRNA

NCBI chr10:54,704,367...54,713,781
Ensembl chr10:54,704,148...54,713,781

G

CTD small phosphatase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDSP1 mRNA

NCBI chr 9:75,973,694...75,979,298
Ensembl chr 9:75,973,962...75,979,297

G

CTD small phosphatase like

decreases expression

sulforaphane results in decreased expression of CTDSPL mRNA

NCBI chr 8:118,642,729...118,767,238
Ensembl chr 8:118,642,672...118,767,117

G

CTD small phosphatase like 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of CTDSPL2 mRNA

NCBI chr 3:108,915,263...108,970,620
Ensembl chr 3:108,915,280...108,967,227

G

cystathionine gamma-lyase

increases response to substance
decreases expression

CTH protein results in increased susceptibility to sulforaphane
sulforaphane results in decreased expression of CTH mRNA

PMID:22005276 PMID:30529165

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

catenin delta 1

increases expression

sulforaphane results in increased expression of CTNND1 mRNA

NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516

G

cathepsin G

decreases expression

sulforaphane results in decreased expression of CTSG mRNA

NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353

G

cathepsin L

increases expression

sulforaphane results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cathepsin O

increases expression

sulforaphane results in increased expression of CTSO mRNA

NCBI chr 2:167,230,407...167,254,761
Ensembl chr 2:167,230,330...167,253,702

G

CTTNBP2 N-terminal like

decreases expression

sulforaphane results in decreased expression of CTTNBP2NL mRNA

NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101

G

cortexin 1

decreases expression

sulforaphane results in decreased expression of CTXN1 mRNA

NCBI chr12:2,610,465...2,612,076

G

cullin 3

multiple interactions

sulforaphane inhibits the reaction [KEAP1 protein binds to CUL3 protein]

PMID:18417180 PMID:30261176

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

G

C-X-C motif chemokine ligand 1

multiple interactions
increases expression
decreases expression

sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]
sulforaphane results in increased expression of CXCL1 mRNA
sulforaphane metabolite results in decreased expression of CXCL1 mRNA; sulforaphane results in decreased expression of CXCL1 mRNA

PMID:32387680 PMID:35724838

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 17

increases expression

sulforaphane results in increased expression of CXCL17 mRNA

NCBI chr 1:80,984,751...80,996,842
Ensembl chr 1:80,984,964...80,996,726

G

C-X-C motif chemokine ligand 2

increases expression

sulforaphane results in increased expression of CXCL2 mRNA

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

decreases expression
increases expression
multiple interactions

sulforaphane metabolite results in decreased expression of CXCL1 mRNA; sulforaphane results in decreased expression of CXCL1 mRNA
sulforaphane results in increased expression of CXCL1 mRNA
sulforaphane inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]; sulforaphane metabolite inhibits the reaction [[Tobacco Smoke Pollution co-treated with Particulate Matter] results in increased expression of CXCL1 mRNA]

PMID:32387680 PMID:35724838

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine receptor 5

increases expression

sulforaphane results in increased expression of CXCR5 mRNA

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

G

cytochrome b-245 beta chain

increases expression

sulforaphane results in increased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome c-1

increases expression

sulforaphane results in increased expression of CYC1 mRNA

NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479

G

cytochrome c, somatic

increases expression

sulforaphane results in increased expression of CYCS mRNA

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytoplasmic FMR1 interacting protein 2

increases expression

sulforaphane results in increased expression of CYFIP2 mRNA

NCBI chr10:30,621,318...30,741,113
Ensembl chr10:30,621,318...30,741,113

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression
affects binding
affects expression
multiple interactions

sulforaphane results in increased expression of CYP1A1 protein
sulforaphane binds to CYP1A1 protein
sulforaphane analog affects the expression of CYP1A1 mRNA
sulforaphane inhibits the reaction [anthracene results in increased activity of CYP1A1 protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A1 protein]
sulforaphane analog inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; sulforaphane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; sulforaphane results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]

PMID:18823965 PMID:19202560 PMID:19362136 PMID:22643862 PMID:22664424 More...

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

increases expression
multiple interactions
decreases expression

sulforaphane results in increased expression of CYP1A2 protein
sulforaphane results in decreased activity of [CYP1A2 protein co-treated with CYP1A1 protein]
sulforaphane inhibits the reaction [1,2,5,6-dibenzanthracene results in increased activity of CYP1A2 protein]; sulforaphane inhibits the reaction [anthracene results in increased activity of CYP1A2 protein]; sulforaphane inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein]
sulforaphane results in decreased expression of CYP1A2 mRNA

PMID:15906351 PMID:19202560 PMID:19362136 PMID:20442190 PMID:22664424

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

increases expression

sulforaphane results in increased expression of CYP1B1 protein
sulforaphane results in increased expression of CYP1B1 mRNA

PMID:18823965 PMID:26833863

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily b, polypeptide 1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of CYP26B1 mRNA

NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 mRNA]; sulforaphane inhibits the reaction [cyanoginosin LR results in increased expression of CYP2E1 protein]
sulforaphane results in increased expression of CYP2E1 mRNA

PMID:21684301 PMID:30529165

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 39, subfamily a, polypeptide 1

increases expression

sulforaphane results in increased expression of CYP39A1 mRNA

NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions
decreases expression
decreases activity
increases expression

sulforaphane results in decreased expression of and results in decreased activity of CYP3A2 protein
sulforaphane results in decreased expression of CYP3A4 mRNA
sulforaphane inhibits the reaction [ginkgolide B results in increased expression of CYP3A4 mRNA]; sulforaphane inhibits the reaction [Rifampin results in increased expression of CYP3A4]
sulforaphane results in decreased activity of CYP3A2 protein
sulforaphane results in increased expression of CYP3A2 protein

PMID:15906351 PMID:18823965 PMID:20442190 PMID:22664424 PMID:23153560 More...

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily f, polypeptide 18

increases expression

sulforaphane results in increased expression of CYP4F3 mRNA

PMID:26833863 PMID:31838189

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450 family 7 subfamily A member 1

decreases expression

sulforaphane results in decreased expression of CYP7A1 mRNA

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

sulforaphane results in decreased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

DAB adaptor protein 2

decreases expression

sulforaphane results in decreased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

decreases expression

sulforaphane results in decreased expression of DAPP1 mRNA

NCBI chr 2:226,425,890...226,475,445
Ensembl chr 2:226,425,898...226,475,423

G

DDB1 and CUL4 associated factor 7

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DCAF7 mRNA

NCBI chr10:90,974,095...90,996,275
Ensembl chr10:90,974,095...90,996,275

G

decorin

increases expression
decreases expression

sulforaphane results in increased expression of DCN mRNA
sulforaphane results in decreased expression of DCN mRNA

PMID:30529165 PMID:31838189

NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270

G

dendrocyte expressed seven transmembrane protein

increases expression

sulforaphane results in increased expression of DCSTAMP mRNA

NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078

G

dimethylarginine dimethylaminohydrolase 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DDAH1 mRNA

NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339

G

DDAH family member 2, ADMA-independent

decreases expression

sulforaphane results in decreased expression of DDAH2 mRNA

NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511

G

damage specific DNA binding protein 2

decreases expression

sulforaphane results in decreased expression of DDB2 mRNA

NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631

G

DNA damage-induced apoptosis suppressor

increases expression

sulforaphane results in increased expression of DDIAS mRNA

NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

sulforaphane inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
sulforaphane results in increased expression of DDIT3 protein
sulforaphane inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]

PMID:22922937 PMID:24967692 PMID:35724838 PMID:36670177

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

dendrin

decreases expression

sulforaphane results in decreased expression of DDN mRNA

NCBI chr 7:129,953,317...129,957,299
Ensembl chr 7:129,953,318...129,957,341

G

2,4-dienoyl-CoA reductase 1

increases expression

sulforaphane results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

death effector domain-containing

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DEDD mRNA

NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332

G

death effector domain containing 2

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DEDD2 mRNA

NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714

G

DENN domain containing 2B

decreases expression

sulforaphane results in decreased expression of DENND2B mRNA

NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680

G

DENN domain containing 3

decreases expression

sulforaphane results in decreased expression of DENND3 mRNA

NCBI chr 7:105,415,870...105,473,583
Ensembl chr 7:105,415,677...105,473,592

G

DEP domain containing 1

increases expression

sulforaphane results in increased expression of DEPDC1 mRNA

NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951

G

DEP domain containing MTOR-interacting protein

decreases expression

sulforaphane results in decreased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

desmin

affects binding
increases expression

DES protein binds to sulforaphane
sulforaphane results in increased expression of DES mRNA

PMID:21838287 PMID:30529165

NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699

G

deuterosome assembly protein 1

increases expression

sulforaphane results in increased expression of DEUP1 mRNA

NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199

G

diacylglycerol O-acyltransferase 1

multiple interactions

sulforaphane inhibits the reaction [bisphenol A results in increased expression of DGAT1 mRNA]

NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299

G

diacylglycerol O-acyltransferase 2

increases expression

sulforaphane results in increased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

DGCR8 microprocessor complex subunit

decreases expression

sulforaphane results in decreased expression of DGCR8 mRNA

NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242

G

24-dehydrocholesterol reductase

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DHCR24 mRNA

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

dehydrogenase/reductase 11

increases expression
decreases expression

sulforaphane results in increased expression of DHRS11 mRNA
sulforaphane results in decreased expression of DHRS11 mRNA

PMID:30529165 PMID:31838189

NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295

G

dehydrogenase/reductase 7C

increases expression

sulforaphane results in increased expression of DHRS7C mRNA

NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338

G

DIM1 rRNA methyltransferase and ribosome maturation factor

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DIMT1 mRNA

NCBI chr 2:38,343,086...38,368,242
Ensembl chr 2:38,354,854...38,368,227

G

iodothyronine deiodinase 2

decreases expression

sulforaphane results in decreased expression of DIO2 mRNA

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression
increases methylation

sulforaphane results in decreased expression of DKK1 mRNA
sulforaphane results in increased methylation of DKK1 gene

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 3

decreases expression

sulforaphane results in decreased expression of DKK3 mRNA

NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590

G

dihydrolipoamide S-acetyltransferase

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DLAT mRNA
sulforaphane results in increased expression of DLAT mRNA

PMID:25450479 PMID:30529165

NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479

G

discs large MAGUK scaffold protein 1

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of DLG1 mRNA

NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689

G

discs large MAGUK scaffold protein 3

decreases expression

sulforaphane results in decreased expression of DLG3 mRNA

NCBI chr X:65,859,653...65,911,887
Ensembl chr X:65,860,172...65,910,322

G

DLG associated protein 5

increases expression

sulforaphane results in increased expression of DLGAP5 mRNA

NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518

G

delta like non-canonical Notch ligand 2

decreases expression

sulforaphane results in decreased expression of DLK2 mRNA

NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594

G

distal-less homeobox 3

decreases expression

sulforaphane results in decreased expression of DLX3 mRNA

NCBI chr10:80,064,489...80,069,891
Ensembl chr10:80,064,489...80,069,872

G

distal-less homeobox 4

decreases expression

sulforaphane results in decreased expression of DLX4 mRNA

NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,085,465...80,090,456

G

distal membrane arm assembly component 2 like

decreases expression

sulforaphane results in decreased expression of DMAC2L mRNA

NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933

G

dermokine

increases expression

sulforaphane results in increased expression of DMKN mRNA

NCBI chr 1:86,013,237...86,031,243
Ensembl chr 1:86,014,188...86,030,006

G

doublesex and mab-3 related transcription factor 2

increases expression

sulforaphane results in increased expression of DMRT2 mRNA

NCBI chr 1:223,317,543...223,324,131
Ensembl chr 1:223,317,642...223,324,131

G

cyclin D binding myb-like transcription factor 1

decreases expression

sulforaphane results in decreased expression of DMTF1 mRNA

NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967

G

Dmx-like 2

decreases expression

sulforaphane results in decreased expression of DMXL2 mRNA

NCBI chr 8:54,741,164...54,884,948
Ensembl chr 8:54,741,160...54,885,161

G

dynein axonemal intermediate chain 3

increases expression

sulforaphane results in increased expression of DNAI3 mRNA

NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B13

increases expression

sulforaphane results in increased expression of DNAJB13 mRNA

PMID:30529165 PMID:31838189

NCBI chr 1:154,848,586...154,863,042
Ensembl chr 1:154,848,594...154,862,963

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression

sulforaphane results in increased expression of DNAJB4 mRNA

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member C15

increases expression

sulforaphane results in increased expression of DNAJC15 mRNA

NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675

G

DnaJ heat shock protein family (Hsp40) member C17

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DNAJC17 mRNA

NCBI chr 3:106,162,197...106,195,771
Ensembl chr 3:106,162,197...106,195,751

G

dynamin 1-like

increases expression
multiple interactions

sulforaphane results in increased expression of DNM1L protein alternative form
sulforaphane inhibits the reaction [Carbon Monoxide results in increased expression of DNM1L protein]

PMID:27993529 PMID:37860845

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 1

decreases expression
multiple interactions

sulforaphane results in decreased expression of DNMT1 mRNA
sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT1 mRNA]; sulforaphane inhibits the reaction [Genistein results in increased expression of DNMT1 mRNA]

PMID:24466240 PMID:30684530

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 alpha

increases expression

sulforaphane results in increased expression of DNMT3A mRNA

NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687

G

DNA methyltransferase 3 beta

decreases expression
multiple interactions

sulforaphane results in decreased expression of DNMT3B mRNA
sulforaphane inhibits the reaction [DNMT3B protein binds to COMT promoter]; sulforaphane inhibits the reaction [Estradiol promotes the reaction [DNMT3B protein binds to COMT promoter]]; sulforaphane inhibits the reaction [Estradiol results in increased expression of DNMT3B mRNA]

PMID:24466240 PMID:30684530

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

deoxynucleotidyltransferase, terminal, interacting protein 2

increases expression

sulforaphane results in increased expression of DNTTIP2 mRNA

NCBI chr 2:210,374,321...210,386,366
Ensembl chr 2:210,374,289...210,385,581

G

dedicator of cytokinesis 4

decreases expression

sulforaphane results in decreased expression of DOCK4 mRNA

NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855

G

dedicator of cytokinesis 8

decreases expression

sulforaphane results in decreased expression of DOCK8 mRNA

NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474

G

docking protein 7

increases expression

sulforaphane results in increased expression of DOK7 mRNA

NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386

G

diphthamide biosynthesis 5

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DPH5 mRNA

NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433

G

dihydropyrimidine dehydrogenase

increases expression

sulforaphane results in increased expression of DPYD mRNA

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

DNA-damage regulated autophagy modulator 1

decreases expression

sulforaphane results in decreased expression of DRAM1 mRNA

NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765

G

dynein regulatory complex subunit 12 homolog

increases expression

sulforaphane results in increased expression of CCDC153 mRNA

NCBI chr 8:44,576,528...44,584,345
Ensembl chr 8:44,577,836...44,584,338

G

dopamine receptor D1

multiple interactions

sulforaphane inhibits the reaction [Buthionine Sulfoximine results in decreased expression of DRD1 protein]

NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002

G

desmocollin 2

increases expression

sulforaphane results in increased expression of DSC2 mRNA

NCBI chr18:11,450,392...11,482,476
Ensembl chr18:11,450,390...11,482,392

G

desmoglein 2

increases expression

sulforaphane results in increased expression of DSG2 mRNA

NCBI chr18:11,846,207...11,904,630
Ensembl chr18:11,846,183...11,904,156

G

desmoplakin

increases expression

sulforaphane results in increased expression of DSP mRNA

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dual specificity phosphatase 10

decreases expression

sulforaphane results in decreased expression of DUSP10 mRNA

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 16

increases expression
decreases expression

sulforaphane results in increased expression of DUSP16 mRNA
sulforaphane results in decreased expression of DUSP16 mRNA

PMID:26833863 PMID:31838189

NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980

G

dual specificity phosphatase 4

increases expression

sulforaphane results in increased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

dual specificity phosphatase 5

increases expression

sulforaphane results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dual specificity phosphatase 6

increases expression

sulforaphane results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

dual specificity phosphatase 8

decreases expression

sulforaphane results in decreased expression of DUSP8 mRNA

NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921

G

dual specificity phosphatase 9

decreases expression

sulforaphane results in decreased expression of DUSP9 mRNA

NCBI chr X:151,351,897...151,355,822
Ensembl chr X:151,351,897...151,355,821

G

dynein cytoplasmic 1 heavy chain 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNC1H1 mRNA

NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883

G

dynein 2 intermediate chain 2

decreases expression

sulforaphane results in decreased expression of DYNC2I2 mRNA

NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121

G

dynein light chain Tctex-type 3

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

E2F transcription factor 1

decreases expression

sulforaphane results in decreased expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

increases methylation

sulforaphane results in increased methylation of E2F3 gene

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

EBF transcription factor 2

increases expression

sulforaphane results in increased expression of EBF2 mRNA

NCBI chr15:41,435,509...41,634,403
Ensembl chr15:41,435,509...41,634,403

G

enoyl-CoA hydratase 1

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ECH1 mRNA
sulforaphane results in increased expression of ECH1 mRNA

PMID:25450479 PMID:30529165

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

endothelin receptor type A

decreases expression

sulforaphane results in decreased expression of EDNRA mRNA

NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049

G

eukaryotic translation elongation factor 1 alpha 2

increases expression

sulforaphane results in increased expression of EEF1A2 mRNA

NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071

G

eukaryotic elongation factor-2 kinase

decreases expression

sulforaphane results in decreased expression of EEF2K mRNA

NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164

G

EF-hand domain family, member D1

decreases expression

sulforaphane results in decreased expression of EFHD1 mRNA

NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917

G

ephrin A1

decreases expression

sulforaphane results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

ephrin B2

decreases expression

sulforaphane results in decreased expression of EFNB2 mRNA

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

EFR3 homolog B

decreases expression

sulforaphane results in decreased expression of EFR3B mRNA

NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933

G

EGF-like-domain, multiple 6

decreases expression

sulforaphane results in decreased expression of EGFL6 mRNA

NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044

G

ets homologous factor

decreases expression

sulforaphane results in decreased expression of EHF mRNA

NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997

G

EP300 interacting inhibitor of differentiation 3

increases expression

sulforaphane results in increased expression of EID3 mRNA

NCBI chr 7:20,860,073...20,861,395

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions
increases expression

sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form]
sulforaphane results in increased expression of EIF2AK3 protein modified form

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 alpha kinase 4

decreases expression

sulforaphane results in decreased expression of EIF2AK4 mRNA

NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions
increases expression

sulforaphane inhibits the reaction [bisphenol A results in increased phosphorylation of EIF2S1 protein]; sulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of EIF2S1 protein modified form]
sulforaphane results in increased expression of EIF2S1 protein modified form

PMID:22922937 PMID:36670177

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 4E family member 3

increases expression

sulforaphane results in increased expression of EIF4E3 mRNA

NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808

G

eukaryotic translation initiation factor 5

increases expression

sulforaphane results in increased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 5A

affects binding

EIF5A protein binds to sulforaphane

NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656

G

eukaryotic translation initiation factor 5A2

increases expression

sulforaphane results in increased expression of EIF5A2 mRNA

NCBI chr 2:111,728,587...111,746,087
Ensembl chr 2:111,729,323...111,746,087

G

E74 like ETS transcription factor 3

decreases expression

sulforaphane results in decreased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

extracellular leucine-rich repeat and fibronectin type III domain containing 1

decreases expression

sulforaphane results in decreased expression of ELFN1 mRNA

NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

decreases expression

sulforaphane results in decreased expression of ELFN2 mRNA

NCBI chr 7:110,220,293...110,272,770
Ensembl chr 7:110,225,919...110,272,433

G

elongation factor for RNA polymerase II 2

increases expression

sulforaphane results in increased expression of ELL2 mRNA

NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781

G

ELOVL fatty acid elongase 6

multiple interactions
increases expression

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ELOVL6 mRNA
sulforaphane results in increased expression of ELOVL6 mRNA

PMID:25450479 PMID:31838189

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

epithelial membrane protein 2

decreases expression

sulforaphane results in decreased expression of EMP2 mRNA

NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733

G

epithelial membrane protein 3

decreases expression

sulforaphane results in decreased expression of EMP3 mRNA

NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988

G

ectodermal-neural cortex 1

increases expression

sulforaphane results in increased expression of ENC1 mRNA

NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713

G

endonuclease G

increases expression

sulforaphane results in increased expression of ENDOG protein

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

enkurin, TRPC channel interacting protein

increases expression

sulforaphane results in increased expression of ENKUR mRNA

NCBI chr17:83,690,105...83,714,756
Ensembl chr17:83,690,797...83,714,408

G

enolase 3

decreases expression

sulforaphane results in decreased expression of ENO3 mRNA

NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921

G

glutamyl aminopeptidase

decreases expression

sulforaphane results in decreased expression of ENPEP mRNA

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression

sulforaphane results in decreased expression of ENPP2 mRNA

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleoside triphosphate diphosphohydrolase 2

increases expression
decreases expression

sulforaphane results in increased expression of ENTPD2 mRNA
sulforaphane results in decreased expression of ENTPD2 mRNA

PMID:30529165 PMID:31838189

NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

sulforaphane results in increased expression of ENTPD5 mRNA

NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530

G

endosomal transmembrane epsin interactor 1

decreases expression

sulforaphane results in decreased expression of ENTREP1 mRNA

NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758

G

E1A binding protein p300

multiple interactions

sulforaphane inhibits the reaction [EP300 protein binds to COMT promoter]

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

erythrocyte membrane protein band 4.1-like 1

decreases expression

sulforaphane results in decreased expression of EPB41L1 mRNA

NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721

G

erythrocyte membrane protein band 4.1 like 4A

decreases expression

sulforaphane results in decreased expression of EPB41L4A mRNA

NCBI chr18:25,405,461...25,615,392
Ensembl chr18:25,406,057...25,615,149

G

ependymin related 1

increases expression

sulforaphane results in increased expression of EPDR1 mRNA

NCBI chr17:45,333,932...45,358,597
Ensembl chr17:45,333,956...45,358,594

G

epithelial mitogen

increases expression

sulforaphane results in increased expression of EPGN mRNA

NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806

G

Eph receptor A7

decreases expression

sulforaphane results in decreased expression of EPHA7 mRNA

NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112

G

epoxide hydrolase 1

increases expression
multiple interactions

sulforaphane results in increased expression of EPHX1 mRNA
sulforaphane results in increased expression of EPHX1 exon; sulforaphane results in increased expression of EPHX1 mRNA; sulforaphane results in increased expression of EPHX1 protein; sulforaphane results in increased expression of EPHX1 protein alternative form
sulforaphane promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer]
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA

PMID:17942926 PMID:24704207 PMID:31838189

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

epoxide hydrolase 2

increases expression

sulforaphane results in increased expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

ERCC excision repair 4, endonuclease catalytic subunit

increases expression

sulforaphane results in increased expression of ERCC4 mRNA

NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
Ensembl chr10:2,419,038...2,448,369

G

ERCC excision repair 5, endonuclease

increases expression

sulforaphane results in increased expression of ERCC5 mRNA

NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472

G

Ets2 repressor factor

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of ERF mRNA

NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388

G

ETS transcription factor ERG

decreases expression
multiple interactions

sulforaphane results in decreased expression of ERG mRNA; sulforaphane results in decreased expression of ERG protein
sulforaphane inhibits the reaction [AR protein binds to ERG enhancer]

NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871

G

endoregulin

increases expression
multiple interactions

sulforaphane results in increased expression of ERLN mRNA
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ERLN mRNA

NCBI chr10:101,144,577...101,147,160

G

endoplasmic reticulum oxidoreductase 1 alpha

increases expression

sulforaphane results in increased expression of ERO1A protein

NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478

G

ERBB receptor feedback inhibitor 1

decreases expression

sulforaphane results in decreased expression of ERRFI1 mRNA

NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282

G

espin

decreases expression

sulforaphane results in decreased expression of ESPN mRNA

NCBI chr 5:162,626,560...162,660,439
Ensembl chr 5:162,626,560...162,660,256

G

estrogen receptor 1

multiple interactions

ESR1 mutant form promotes the reaction [3,3'-diindolylmethane promotes the reaction [sulforaphane results in increased expression of HMOX1 mRNA]]

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

extended synaptotagmin 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ESYT2 mRNA

NCBI chr 6:137,219,653...137,312,590
Ensembl chr 6:137,219,707...137,312,590

G

eukaryotic translation termination factor 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of ETF1 mRNA

NCBI chr18:26,502,413...26,530,753
Ensembl chr18:26,504,080...26,530,810

G

electron transfer flavoprotein subunit alpha

increases expression

sulforaphane results in increased expression of ETFA mRNA

NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969

G

electron transfer flavoprotein subunit beta

increases expression

sulforaphane results in increased expression of ETFB mRNA

NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068

G

electron transfer flavoprotein dehydrogenase

increases expression

sulforaphane results in increased expression of ETFDH mRNA

NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745

G

ethanolamine kinase 2

decreases expression

sulforaphane results in decreased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

ethanolamine-phosphate phospho-lyase

decreases expression

sulforaphane results in decreased expression of ETNPPL mRNA

NCBI chr 2:219,173,048...219,194,646
Ensembl chr 2:219,172,978...219,192,212

G

ETS proto-oncogene 2, transcription factor

decreases expression

sulforaphane results in decreased expression of ETS2 mRNA

NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319

G

ETS variant transcription factor 4

increases expression

sulforaphane results in increased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

ETS variant transcription factor 5

decreases expression
increases expression

sulforaphane results in decreased expression of ETV5 mRNA
sulforaphane results in increased expression of ETV5 mRNA

PMID:30529165 PMID:31838189

NCBI chr11:78,608,618...78,666,221
Ensembl chr11:78,608,710...78,666,215

G

exocyst complex component 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EXOC1 mRNA

NCBI chr14:31,611,536...31,659,920
Ensembl chr14:31,611,547...31,659,914

G

exostosin glycosyltransferase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EXT2 mRNA

NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059

G

EYA transcriptional coactivator and phosphatase 4

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of EYA4 mRNA

NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976

G

F11 receptor

decreases expression

sulforaphane results in decreased expression of F11R mRNA

NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402

G

coagulation factor XII

decreases expression

sulforaphane results in decreased expression of F12 mRNA

NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530

G

coagulation factor XIII A1 chain

decreases expression

sulforaphane results in decreased expression of F13A1 mRNA

NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700

G

coagulation factor III, tissue factor

increases expression

sulforaphane results in increased expression of F3 mRNA; sulforaphane results in increased expression of F3 protein

PMID:31838189 PMID:33814512

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor VII

decreases expression

sulforaphane results in decreased expression of F7 mRNA

NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610

G

fatty acid 2-hydroxylase

decreases expression

sulforaphane results in decreased expression of FA2H mRNA

NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153

G

fatty acid binding protein 3

increases expression
decreases expression

sulforaphane results in increased expression of FABP3 mRNA
sulforaphane results in decreased expression of FABP3 mRNA

PMID:30529165 PMID:31838189

NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718

G

fatty acid binding protein 4

increases expression

sulforaphane results in increased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

family with sequence similarity 13, member C

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FAM13C mRNA

NCBI chr20:18,065,625...18,187,792
Ensembl chr20:18,065,628...18,187,592

G

FAM161 centrosomal protein A

decreases expression

sulforaphane results in decreased expression of FAM161A mRNA

NCBI chr14:97,009,449...97,027,865
Ensembl chr14:97,009,491...97,028,588

G

family with sequence similarity 167, member B

decreases expression

sulforaphane results in decreased expression of FAM167B mRNA

NCBI chr 5:141,920,695...141,922,342
Ensembl chr 5:141,920,695...141,922,340

G

family with sequence similarity 216, member B

increases expression

sulforaphane results in increased expression of FAM216B mRNA

NCBI chr15:53,469,495...53,482,385
Ensembl chr15:53,469,599...53,482,398

G

family with sequence similarity 43, member A

increases expression

sulforaphane results in increased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

family with sequence similarity 72, member A

increases expression

sulforaphane results in increased expression of FAM72A mRNA

NCBI chr13:42,967,701...42,979,083
Ensembl chr13:42,967,578...42,984,208

G

family with sequence similarity 81, member A

increases expression

sulforaphane results in increased expression of FAM81A mRNA

NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875

G

family with sequence similarity 83, member A

decreases expression

sulforaphane results in decreased expression of FAM83A mRNA

NCBI chr 7:89,522,826...89,547,284
Ensembl chr 7:89,522,826...89,547,388

G

family with sequence similarity 83, member E

increases expression

sulforaphane results in increased expression of FAM83E mRNA

NCBI chr 1:96,191,581...96,201,182
Ensembl chr 1:96,191,742...96,201,192

G

FA complementation group A

increases expression

sulforaphane results in increased expression of FANCA mRNA

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases expression

sulforaphane results in decreased expression of FARP1 mRNA

NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299

G

Fas cell surface death receptor

increases expression

sulforaphane results in increased expression of FAS mRNA; sulforaphane results in increased expression of FAS protein

PMID:26833863 PMID:31838189

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

increases expression

sulforaphane results in increased expression of FASLG protein

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

fatty acid synthase

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FASN mRNA
sulforaphane inhibits the reaction [bisphenol A results in increased expression of FASN mRNA]

PMID:25450479 PMID:36670177

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fibulin 1

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FBLN1 mRNA

NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075

G

fibrillin 2

decreases expression

sulforaphane results in decreased expression of FBN2 mRNA

NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976

G

F-box and leucine-rich repeat protein 12

decreases expression

sulforaphane results in decreased expression of FBXL12 mRNA

NCBI chr 8:19,175,864...19,183,373
Ensembl chr 8:19,160,352...19,183,607

G

F-box protein 11

decreases expression

sulforaphane results in decreased expression of FBXO11 mRNA

NCBI chr 6:6,486,761...6,562,664
Ensembl chr 6:6,486,015...6,562,662

G

F-box protein 2

decreases expression

sulforaphane results in decreased expression of FBXO2 mRNA

NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355

G

F-box protein 32

decreases expression

sulforaphane results in decreased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 4

decreases expression

sulforaphane results in decreased expression of FBXO4 mRNA

NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792

G

Fc alpha receptor

increases expression

sulforaphane results in increased expression of FCAR mRNA

NCBI chr 1:69,626,458...69,660,558

G

FCH and mu domain containing endocytic adaptor 2

decreases expression

sulforaphane results in decreased expression of FCHO2 mRNA

NCBI chr 2:30,079,143...30,181,639
Ensembl chr 2:30,080,962...30,181,241

G

Fc mu receptor

increases expression

sulforaphane results in increased expression of FCMR mRNA

NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653

G

ferrochelatase

increases expression

sulforaphane results in increased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

fetuin B

increases expression

sulforaphane results in increased expression of FETUB mRNA

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

free fatty acid receptor 2

increases expression

sulforaphane results in increased expression of FFAR2 mRNA

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

G

FYVE, RhoGEF and PH domain containing 6

decreases expression

sulforaphane results in decreased expression of FGD6 mRNA

NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456

G

fibroblast growth factor 1

decreases expression

sulforaphane results in decreased expression of FGF1 mRNA

NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357

G

fibroblast growth factor binding protein 1

decreases expression

sulforaphane results in decreased expression of FGFBP1 mRNA

NCBI chr14:67,103,686...67,107,492
Ensembl chr14:67,104,545...67,107,496

G

fibroblast growth factor receptor 3

decreases expression

sulforaphane results in decreased expression of FGFR3 mRNA

NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341

G

fibrinogen-like 2

increases expression

sulforaphane results in increased expression of FGL2 mRNA

NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207

G

four and a half LIM domains 1

decreases expression

sulforaphane results in decreased expression of FHL1 mRNA

NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928

G

four and a half LIM domains 2

decreases expression

sulforaphane results in decreased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

formin homology 2 domain containing 3

increases expression

sulforaphane results in increased expression of FHOD3 mRNA

NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796

G

folliculogenesis specific bHLH transcription factor

increases expression

sulforaphane results in increased expression of FIGLA mRNA

NCBI chr 4:118,432,517...118,436,846
Ensembl chr 4:118,432,765...118,436,690

G

fission, mitochondrial 1

increases expression

sulforaphane results in increased expression of FIS1 protein

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FLVCR choline and putative heme transporter 2

decreases expression

sulforaphane results in decreased expression of FLVCR2 mRNA

NCBI chr 6:105,408,355...105,472,355
Ensembl chr 6:105,408,339...105,472,353

G

fibronectin type III domain containing 3B

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FNDC3B mRNA

NCBI chr 2:110,311,439...110,617,504
Ensembl chr 2:110,312,694...110,547,830

G

fibronectin type III domain containing 5

increases expression
multiple interactions

sulforaphane results in increased expression of FNDC5 mRNA
[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FNDC5 mRNA

NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731

G

folate receptor alpha

decreases expression

sulforaphane results in decreased expression of FOLR1 mRNA

NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667

G

folate receptor beta

increases expression

sulforaphane results in increased expression of FOLR2 mRNA

NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724

G

FOS like 1, AP-1 transcription factor subunit

increases expression
increases methylation

sulforaphane results in increased expression of FOSL1 mRNA
sulforaphane results in increased methylation of FOSL1 gene

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box A3

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box C2

decreases expression

sulforaphane results in decreased expression of FOXC2 mRNA

NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737

G

forkhead box Q1

decreases expression

sulforaphane results in decreased expression of FOXQ1 mRNA

NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377

G

formyl peptide receptor 1

increases expression

sulforaphane results in increased expression of FPR1 mRNA

NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559

G

formyl peptide receptor 2

increases expression

sulforaphane results in increased expression of FPR2 mRNA

NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019

G

Fraser extracellular matrix complex subunit 1

decreases expression

sulforaphane results in decreased expression of FRAS1 mRNA

NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726

G

ferric-chelate reductase 1

multiple interactions

[NFE2L2 protein affects the susceptibility to sulforaphane] which affects the expression of FRRS1 mRNA

NCBI chr 2:204,820,898...204,881,487
Ensembl chr 2:204,823,025...204,895,540

G

ferritin heavy chain 1

increases expression

sulforaphane results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

increases expression

sulforaphane results in increased expression of FTL mRNA

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
Ensembl chr 2:95,936,387...95,939,725

G

fucose mutarotase

increases expression

sulforaphane results in increased expression of FUOM mRNA

NCBI chr 1:194,888,535...194,893,046
Ensembl chr 1:194,886,709...194,893,046

G

FMR1 autosomal homolog 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of FXR2 mRNA

NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964

G

frizzled class receptor 7

increases expression

sulforaphane results in increased expression of FZD7 mRNA

NCBI chr 9:60,931,433...60,934,252
Ensembl chr 9:60,930,875...60,935,781

G

G3BP stress granule assembly factor 2

decreases methylation

sulforaphane results in decreased methylation of G3BP2 gene

NCBI chr14:15,932,403...16,020,555
Ensembl chr14:15,987,417...16,020,548

G

glucose-6-phosphate dehydrogenase

increases expression

sulforaphane results in increased expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

GRB2-associated binding protein 2

decreases expression

sulforaphane results in decreased expression of GAB2 mRNA

NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031

G

GABA type A receptor associated protein like 1

increases expression

sulforaphane results in increased expression of GABARAPL1 mRNA

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

GA binding protein transcription factor subunit beta 2

increases expression

sulforaphane results in increased expression of GABPB2 mRNA

NCBI chr 2:182,755,304...182,795,368
Ensembl chr 2:182,761,359...182,795,109

G

growth arrest and DNA-damage-inducible, alpha

increases expression

sulforaphane results in increased expression of GADD45A mRNA

PMID:17937621 PMID:26833863

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

polypeptide N-acetylgalactosaminyltransferase 12

increases expression

sulforaphane results in increased expression of GALNT12 mRNA

NCBI chr 5:61,384,575...61,413,346
Ensembl chr 5:61,384,571...61,413,354

G

polypeptide N-acetylgalactosaminyltransferase-like 6

decreases expression

sulforaphane results in decreased expression of GALNTL6 mRNA

NCBI chr16:31,192,880...32,443,979
Ensembl chr16:31,186,462...32,441,960

G

glycyl-tRNA synthetase 1

increases expression

sulforaphane results in increased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest-specific 1

decreases expression

sulforaphane results in decreased expression of GAS1 mRNA

NCBI chr17:4,482,168...4,485,153

G

growth arrest specific 7

increases expression

sulforaphane results in increased expression of GAS7 mRNA

NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276

G

glutamyl-tRNA amidotransferase subunit C

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of GATC mRNA

NCBI chr12:41,270,096...41,278,067
Ensembl chr12:41,270,087...41,277,995

G

glycine amidinotransferase

decreases expression

sulforaphane results in decreased expression of GATM mRNA

NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129

G

GTP cyclohydrolase I feedback regulator

decreases expression

sulforaphane results in decreased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions
decreases expression
decreases methylation
increases expression

[sulforaphane co-treated with Acetaminophen] results in increased expression of GCLC mRNA; [sulforaphane co-treated with dibenzoylmethane] results in increased expression of GCLC mRNA; NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLC mRNA]; sulforaphane inhibits the reaction [Acetaminophen results in decreased expression of GCLC mRNA]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]
sulforaphane results in decreased expression of GCLC mRNA
sulforaphane results in decreased methylation of GCLC gene
sulforaphane results in increased expression of GCLC mRNA; sulforaphane results in increased expression of GCLC protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]
alpha-methylepinine promotes the reaction [sulforaphane results in increased expression of GCLC mRNA]; NFE2L2 mutant form inhibits the reaction [sulforaphane results in increased expression of GCLC mRNA]; sulforaphane promotes the reaction [alpha-methylepinine results in increased expression of GCLC mRNA]; sulforaphane promotes the reaction [Cisplatin results in increased expression of GCLC mRNA]

PMID:17942926 PMID:19071154 PMID:19303893 PMID:20442190 PMID:20932822 More...

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

multiple interactions
decreases expression
increases expression

NFE2L2 protein promotes the reaction [sulforaphane results in increased expression of GCLM mRNA]; sulforaphane inhibits the reaction [Acetaminophen results in decreased expression of GCLM mRNA]; sulforaphane inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLM protein]
sulforaphane results in decreased expression of GCLM mRNA
NFE2L2 protein affects the reaction [sulforaphane results in increased expression of GCLM protein]
sulforaphane results in increased expression of GCLM mRNA; sulforaphane results in increased expression of GCLM protein
sulforaphane results in increased expression of GCLM; sulforaphane results in increased expression of GCLM mRNA; sulforaphane results in increased expression of GCLM protein

PMID:19071154 PMID:19303893 PMID:20442190 PMID:20932822 PMID:21539383 More...

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

sulforaphane results in increased expression of GCNT3 mRNA

NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562

G

growth differentiation factor 11

decreases expression

sulforaphane results in decreased expression of GDF11 mRNA

NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725

G

glycerophosphodiester phosphodiesterase domain containing 5

decreases expression

sulforaphane results in decreased expression of GDPD5 mRNA

NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446

G

GIPC PDZ domain containing family, member 3

decreases expression

sulforaphane results in decreased expression of GIPC3 mRNA

NCBI chr 7:8,374,941...8,383,281

G

gap junction protein, alpha 5

decreases expression

sulforaphane results in decreased expression of GJA5 mRNA

NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952

G

galactosidase, alpha

increases expression

sulforaphane results in increased expression of GLA mRNA

NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664

G

galactosidase, beta 1-like 3

decreases expression

sulforaphane results in decreased expression of GLB1L3 mRNA

NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904

G

glyoxalase 1

multiple interactions
increases expression

sulforaphane inhibits the reaction [Pyruvaldehyde results in decreased expression of GLO1 protein]
sulforaphane results in increased expression of GLO1 protein

NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649

G

glutaredoxin

increases expression

sulforaphane results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

GDP-mannose 4, 6-dehydratase

decreases expression

sulforaphane results in decreased expression of GMDS mRNA

NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961

G

geminin, DNA replication inhibitor

increases expression

sulforaphane results in increased expression of GMNN mRNA

NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054

G

guanosine monophosphate reductase 2

multiple interactions

[sulforaphane affects the susceptibility to Oxygen] which affects the expression of GMPR2 mRNA

NCBI chr15:29,165,421...29,175,933
Ensembl chr15:29,165,783...29,174,935

G

glucosamine-6-phosphate deaminase 1

increases expression

sulforaphane results in increased expression of GNPDA1 mRNA

NCBI chr18:30,165,435...30,177,462
Ensembl chr18:30,165,427...30,177,486

G

glycerol-3-phosphate acyltransferase 3

increases expression

sulforaphane results in increased expression of GPAT3 mRNA

PMID:26833863 PMID:31838189

NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490

G

glypican 1

increases expression

sulforaphane results in increased expression of GPC1 mRNA

NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047

G

glypican 5

decreases expression

sulforaphane results in decreased expression of GPC5 mRNA

NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282

G

G protein-coupled estrogen receptor 1

decreases expression

sulforaphane results in decreased expression of GPER1 mRNA

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

glycosylphosphatidylinositol specific phospholipase D1

decreases expression

sulforaphane results in decreased expression of GPLD1 mRNA

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

G

glycoprotein m6b

decreases expression

sulforaphane results in decreased expression of GPM6B mRNA

NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211

G

G protein-coupled receptor 135

increases expression

sulforaphane results in increased expression of GPR135 mRNA

NCBI chr 6:90,627,533...90,630,661
Ensembl chr 6:90,629,178...90,630,551

G

G protein-coupled receptor 137C

decreases expression

sulforaphane results in decreased expression of GPR137C mRNA

NCBI chr15:18,425,939...18,492,588
Ensembl chr15:18,426,223...18,490,807

G

G protein-coupled receptor 153

decreases expression

sulforaphane results in decreased expression of GPR153 mRNA

NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971

G

G protein-coupled receptor 22

increases expression

sulforaphane results in increased expression of GPR22 mRNA

NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486

G

G protein-coupled receptor 3

increases expression

sulforaphane results in increased expression of GPR3 mRNA

NCBI chr 5:145,411,500...145,414,621
Ensembl chr 5:145,411,510...145,414,590

G

G protein-coupled receptor 37-like 1

decreases expression

sulforaphane results in decreased expression of GPR37L1 mRNA

NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421

G

G-protein coupled receptor 65

decreases expression

sulforaphane results in decreased expression of GPR65 mRNA

NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512

G

G protein-coupled receptor 84

increases expression

sulforaphane results in increased expression of GPR84 mRNA

NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178

G

G protein-coupled receptor 85

decreases expression

sulforaphane results in decreased expression of GPR85 mRNA

NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566

G

G protein-coupled receptor, class C, group 5, member A

decreases expression

sulforaphane results in decreased expression of GPRC5A mRNA

NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260

G

G protein-coupled receptor, class C, group 5, member B

decreases expression

sulforaphane results in decreased expression of GPRC5B mRNA

NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932

G

G protein regulated inducer of neurite outgrowth 2

decreases expression

sulforaphane results in decreased expression of GPRIN2 mRNA

NCBI chr16:9,496,452...9,512,672
Ensembl chr16:9,505,643...9,507,010

G

G-protein signaling modulator 3

decreases expression

sulforaphane results in decreased expression of GPSM3 mRNA

NCBI chr20:4,157,123...4,158,984
Ensembl chr20:4,157,123...4,159,035

G

glutamic--pyruvic transaminase

multiple interactions

sulforaphane inhibits the reaction [Acetaminophen results in increased activity of GPT protein]

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutamic--pyruvic transaminase 2

multiple interactions

[sulforaphane co-treated with Aflatoxin B1] affects the expression of GPT2 mRNA

NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 1

decreases expression

sulforaphane results in decreased expression of GPX1 mRNA

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

increases expression

sulforaphane results in increased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

decreases expression
multiple interactions
increases expression

sulforaphane results in decreased expression of GPX4 mRNA
sulforaphane inhibits the reaction [Busulfan results in decreased expression of and results in decreased activity of GPX4 protein]
sulforaphane results in increased expression of GPX4 protein

PMID:31838189 PMID:32416107

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

GRAM domain containing 2B

decreases expression

sulforaphane results in decreased expression of GRAMD2B mRNA

NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953

G

growth factor receptor bound protein 10

increases expression

sulforaphane results in increased expression of GRB10 mRNA

NCBI chr14:86,495,051...86,602,800
Ensembl chr14:86,495,054...86,602,806

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

sulforaphane results in decreased expression of GRIA3 mRNA

NCBI chr X:120,238,515...120,504,106
Ensembl chr X:120,238,534...120,504,096

G

glycogen synthase kinase 3 beta

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein]; sulforaphane results in increased phosphorylation of and results in decreased activity of GSK3B protein

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

gelsolin

increases methylation
decreases expression

sulforaphane results in increased methylation of GSN gene
sulforaphane results in decreased expression of GSN mRNA

NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402

G

glutathione-disulfide reductase

decreases activity
increases expression
multiple interactions
increases activity

sulforaphane results in decreased activity of GSR protein
sulforaphane results in increased expression of GSR mRNA
sulforaphane inhibits the reaction [Oxidopamine results in decreased activity of GSR protein]
sulforaphane results in increased activity of GSR protein

PMID:17937621 PMID:19303893 PMID:22664424 PMID:23518299 PMID:26833863 More...

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

multiple interactions
increases expression
decreases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA]; SN50 peptide inhibits the reaction [sulforaphane results in increased expression of GSTA1 mRNA]
sulforaphane results in increased expression of GSTA1 mRNA; sulforaphane results in increased expression of GSTA1 protein
sulforaphane results in decreased expression of GSTA1 mRNA

PMID:11264000 PMID:12151360 PMID:12756216 PMID:12949046 PMID:15090468 More...

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

multiple interactions
increases expression

Hydrocortisone inhibits the reaction [sulforaphane results in increased expression of GSTA2 mRNA]
sulforaphane results in increased expression of GSTA2 mRNA; sulforaphane results in increased expression of GSTA2 protein

PMID:11264000 PMID:11309284 PMID:22606287 PMID:38145809

NCBI chr 8:79,184,535...79,196,827