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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indolecarboxamide
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Accession:CHEBI:46921 term browser browse the term
Synonyms:related_synonym: indolecarboxamides


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delavirdine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Delavirdine results in decreased activity of CYP2C19 protein CTD PMID:11225565 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
devazepide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cck cholecystokinin multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] CTD PMID:32916201 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cckar cholecystokinin A receptor multiple interactions ISO Devazepide inhibits the reaction [CCKAR protein results in increased susceptibility to denatonium] CTD PMID:18003792 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Devazepide inhibits the reaction [8-sulfocholecystokinin octapeptide results in increased expression of FOS protein] CTD PMID:9372230 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]] CTD PMID:32916201 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] CTD PMID:32916201 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
silodosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A affects binding ISO silodosin binds to ADRA1A protein CTD PMID:15306222 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19867
    chemical entity 19865
      atom 19865
        nonmetal atom 19787
          nitrogen atom 18978
            nitrogen molecular entity 18978
              organonitrogen compound 18832
                carboxamide 17551
                  monocarboxylic acid amide 15731
                    indolecarboxamide 7
                      (2-methyl-1-propyl-3-indolyl)-(1-naphthalenyl)methanone 0
                      (4-benzylpiperidin-1-yl)-(5-amidinomethyl-3aH-indol-2-yl)methanone 0
                      1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide 0
                      1-(2-deoxy-5-O-phosphono-beta-D-ribosyl)-5-nitro-1H-indole-3-carboxamide 0
                      1-Butyl-3-(1-naphthoyl)indole 0
                      1-Methylindole-3-carboxylic acid amide 0
                      1-[(1R)-1-(1-ethylsulfonyl-4-piperidinyl)ethyl]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-3-indolecarboxamide 0
                      1-[1-(1-ethylsulfonyl-4-piperidinyl)ethyl]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-3-indolecarboxamide 0
                      1-[1-naphthalenyl(oxo)methyl]-3-indolecarboxylic acid methyl ester 0
                      1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamide 0
                      1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                      1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                      1-methyl-N-(thiophen-2-ylmethylideneamino)-3-indolecarboxamide 0
                      1H-indole-5-carboxamide 0
                      3-[2-(dipropylamino)ethyl]-1H-indole-5-carboxamide 0
                      3-[[3-[(dimethylamino)methyl]anilino]-phenylmethylidene]-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide 0
                      3-amino-4-methoxy-1H-indole-2-carbohydrazide 0
                      3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-\{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl\}-L-phenylalaninamide 0
                      5-chloro-N-[(1S)-1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-1H-indole-2-carboxamide 0
                      5-methoxy-N-(1-methoxypropan-2-yl)-1H-indole-2-carboxamide 0
                      6-[[[(5-bromo-3-phenyl-1H-indol-2-yl)-oxomethyl]hydrazinylidene]methyl]-2,3-dimethoxybenzoic acid 0
                      AM2201 0
                      AM2201 N-(4-fluoropentyl) isomer 0
                      AM2232 0
                      AS-I-145 0
                      Adozelesin 0
                      CGS 7181 0
                      Duocarmycin SA 0
                      Ingliforib 0
                      JWH 018 0
                      JWH 018 N-(5-chloropentyl) analog 0
                      JWH 018 N-pentanoic acid metabolite 0
                      JWH 073 N-(4-hydroxybutyl) metabolite 0
                      JWH 073 N-butanoic acid metabolite 0
                      JWH 398 0
                      JWH 412 N-(5-hydroxypentyl) metabolite 0
                      JWH-018 N-(3-methylbutyl) isomer 0
                      JWH022 0
                      JWH182 0
                      LSM-15495 0
                      LSM-36787 0
                      MAM2201 N-(4-hydroxypentyl) metabolite 0
                      Methanone, (4-ethyl-1-naphthalenyl)[1-(5-hydroxypentyl)-1H-indol-3-yl]- 0
                      Methanone, (4-methoxy-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]- 0
                      Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]- 0
                      Methanone, [1-(3-chloropentyl)-1h-indol-3-yl]-1-naphthalenyl- 0
                      Methanone, [6-hydroxy-1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]-1-naphthalenyl- 0
                      Methoxybrassenin B 0
                      N'-[(2-chlorophenyl)-oxomethyl]-5-(trifluoromethoxy)-1H-indole-2-carbohydrazide 0
                      N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-1H-indole-3-carbohydrazide 0
                      N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                      N-(2,5-dichlorobenzyl)-5-ethyl-1H-indole-2-carboxamide 0
                      N-(4-\{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                      N-(4-\{4-amino-1-[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                      N-(4-\{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                      N-(thiophen-2-ylmethylideneamino)-1H-indole-7-carboxamide 0
                      N-[(1-ethyl-3,5-dimethyl-4-pyrazolyl)methylideneamino]-1H-indole-3-carboxamide 0
                      N-[(2S)-3-cyclohexyl-1-oxo-1-(\{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl\}amino)propan-2-yl]-1H-indole-2-carboxamide 0
                      N-[2-(3,4-diethoxyphenyl)ethyl]-1H-indole-5-carboxamide 0
                      N-[5-amino-4-(1,3-benzothiazol-2-yl)-3-oxo-2H-pyrrol-1-yl]-1H-indole-3-carboxamide 0
                      N-[[1H-indol-2-yl(oxo)methyl]amino]carbamic acid (phenylmethyl) ester 0
                      N-[[3-(2-benzofuranyl)-1-phenyl-4-pyrazolyl]methylideneamino]-1H-indole-3-carboxamide 0
                      N-butyl-5-methoxy-1H-indole-2-carboxamide 0
                      N-hydroxy-1-[(4-methoxyphenyl)methyl]-6-indolecarboxamide 0
                      N-methyl-1H-indole-2-carboxamide 0
                      PF-00835231 + 0
                      PF-07304814 0
                      Pruvanserin 0
                      STS-135 0
                      [1,1'-biphenyl]-2-carboxylic acid, 4'-[[2,3-dimethyl-5-[[[(1s)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1h-indol-1-yl]methyl]- 0
                      beta-d-glucopyranosiduronic acid, 4-[3-(1-naphthalenylcarbonyl)-1h-indol-1-yl]butyl 0
                      beta-d-glucopyranosiduronic acid, 5-[3-(1-naphthalenylcarbonyl)-1h-indol-1-yl]pentyl 0
                      delavirdine + 1
                      devazepide 5
                      fosdevirine 0
                      silodosin 1
                      talmapimod 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19867
    subatomic particle 19865
      composite particle 19865
        hadron 19865
          baryon 19865
            nucleon 19865
              atomic nucleus 19865
                atom 19865
                  main group element atom 19803
                    p-block element atom 19803
                      carbon group element atom 19744
                        carbon atom 19740
                          organic molecular entity 19740
                            heteroorganic entity 19512
                              organochalcogen compound 19273
                                organooxygen compound 19189
                                  carbon oxoacid 18660
                                    carboxylic acid 18657
                                      carboacyl group 17700
                                        univalent carboacyl group 17700
                                          carbamoyl group 17551
                                            carboxamide 17551
                                              monocarboxylic acid amide 15731
                                                indolecarboxamide 7
                                                  (2-methyl-1-propyl-3-indolyl)-(1-naphthalenyl)methanone 0
                                                  (4-benzylpiperidin-1-yl)-(5-amidinomethyl-3aH-indol-2-yl)methanone 0
                                                  1-(2-Naphthylmethyl)-2,3-dioxo-indoline-5-carboxamide 0
                                                  1-(2-deoxy-5-O-phosphono-beta-D-ribosyl)-5-nitro-1H-indole-3-carboxamide 0
                                                  1-Butyl-3-(1-naphthoyl)indole 0
                                                  1-Methylindole-3-carboxylic acid amide 0
                                                  1-[(1R)-1-(1-ethylsulfonyl-4-piperidinyl)ethyl]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-3-indolecarboxamide 0
                                                  1-[1-(1-ethylsulfonyl-4-piperidinyl)ethyl]-N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-3-indolecarboxamide 0
                                                  1-[1-naphthalenyl(oxo)methyl]-3-indolecarboxylic acid methyl ester 0
                                                  1-[2-(dimethylamino)ethyl]-5-methoxy-N-methyl-2-indolecarboxamide 0
                                                  1-\{2-[(4-chlorophenyl)amino]-2-oxoethyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                  1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-3-cyano-N-(1-isopropylpiperidin-4-yl)-7-methyl-1H-indole-2-carboxamide 0
                                                  1-\{[5-(5-chloro-2-thienyl)isoxazol-3-yl]methyl\}-N-(1-isopropylpiperidin-4-yl)-1H-indole-2-carboxamide 0
                                                  1-methyl-N-(thiophen-2-ylmethylideneamino)-3-indolecarboxamide 0
                                                  1H-indole-5-carboxamide 0
                                                  3-[2-(dipropylamino)ethyl]-1H-indole-5-carboxamide 0
                                                  3-[[3-[(dimethylamino)methyl]anilino]-phenylmethylidene]-N,N-dimethyl-2-oxo-1H-indole-6-carboxamide 0
                                                  3-amino-4-methoxy-1H-indole-2-carbohydrazide 0
                                                  3-fluoro-Nalpha-(1H-indol-2-ylcarbonyl)-N-\{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl\}-L-phenylalaninamide 0
                                                  5-chloro-N-[(1S)-1-(4-fluorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-1H-indole-2-carboxamide 0
                                                  5-methoxy-N-(1-methoxypropan-2-yl)-1H-indole-2-carboxamide 0
                                                  6-[[[(5-bromo-3-phenyl-1H-indol-2-yl)-oxomethyl]hydrazinylidene]methyl]-2,3-dimethoxybenzoic acid 0
                                                  AM2201 0
                                                  AM2201 N-(4-fluoropentyl) isomer 0
                                                  AM2232 0
                                                  AS-I-145 0
                                                  Adozelesin 0
                                                  CGS 7181 0
                                                  Duocarmycin SA 0
                                                  Ingliforib 0
                                                  JWH 018 0
                                                  JWH 018 N-(5-chloropentyl) analog 0
                                                  JWH 018 N-pentanoic acid metabolite 0
                                                  JWH 073 N-(4-hydroxybutyl) metabolite 0
                                                  JWH 073 N-butanoic acid metabolite 0
                                                  JWH 398 0
                                                  JWH 412 N-(5-hydroxypentyl) metabolite 0
                                                  JWH-018 N-(3-methylbutyl) isomer 0
                                                  JWH022 0
                                                  JWH182 0
                                                  LSM-15495 0
                                                  LSM-36787 0
                                                  MAM2201 N-(4-hydroxypentyl) metabolite 0
                                                  Methanone, (4-ethyl-1-naphthalenyl)[1-(5-hydroxypentyl)-1H-indol-3-yl]- 0
                                                  Methanone, (4-methoxy-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]- 0
                                                  Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]- 0
                                                  Methanone, [1-(3-chloropentyl)-1h-indol-3-yl]-1-naphthalenyl- 0
                                                  Methanone, [6-hydroxy-1-[2-(4-morpholinyl)ethyl]-1h-indol-3-yl]-1-naphthalenyl- 0
                                                  Methoxybrassenin B 0
                                                  N'-[(2-chlorophenyl)-oxomethyl]-5-(trifluoromethoxy)-1H-indole-2-carbohydrazide 0
                                                  N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-1H-indole-3-carbohydrazide 0
                                                  N-(1-isopropylpiperidin-4-yl)-1-(3-methoxybenzyl)-1H-indole-2-carboxamide 0
                                                  N-(2,5-dichlorobenzyl)-5-ethyl-1H-indole-2-carboxamide 0
                                                  N-(4-\{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                                                  N-(4-\{4-amino-1-[1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                                                  N-(4-\{4-amino-1-[4-(4-methylpiperazin-1-yl)-trans-cyclohexyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                                                  N-(thiophen-2-ylmethylideneamino)-1H-indole-7-carboxamide 0
                                                  N-[(1-ethyl-3,5-dimethyl-4-pyrazolyl)methylideneamino]-1H-indole-3-carboxamide 0
                                                  N-[(2S)-3-cyclohexyl-1-oxo-1-(\{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl\}amino)propan-2-yl]-1H-indole-2-carboxamide 0
                                                  N-[2-(3,4-diethoxyphenyl)ethyl]-1H-indole-5-carboxamide 0
                                                  N-[5-amino-4-(1,3-benzothiazol-2-yl)-3-oxo-2H-pyrrol-1-yl]-1H-indole-3-carboxamide 0
                                                  N-[[1H-indol-2-yl(oxo)methyl]amino]carbamic acid (phenylmethyl) ester 0
                                                  N-[[3-(2-benzofuranyl)-1-phenyl-4-pyrazolyl]methylideneamino]-1H-indole-3-carboxamide 0
                                                  N-butyl-5-methoxy-1H-indole-2-carboxamide 0
                                                  N-hydroxy-1-[(4-methoxyphenyl)methyl]-6-indolecarboxamide 0
                                                  N-methyl-1H-indole-2-carboxamide 0
                                                  PF-00835231 + 0
                                                  PF-07304814 0
                                                  Pruvanserin 0
                                                  STS-135 0
                                                  [1,1'-biphenyl]-2-carboxylic acid, 4'-[[2,3-dimethyl-5-[[[(1s)-1-(4-nitrophenyl)ethyl]amino]carbonyl]-1h-indol-1-yl]methyl]- 0
                                                  beta-d-glucopyranosiduronic acid, 4-[3-(1-naphthalenylcarbonyl)-1h-indol-1-yl]butyl 0
                                                  beta-d-glucopyranosiduronic acid, 5-[3-(1-naphthalenylcarbonyl)-1h-indol-1-yl]pentyl 0
                                                  delavirdine + 1
                                                  devazepide 5
                                                  fosdevirine 0
                                                  silodosin 1
                                                  talmapimod 0
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