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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-acylpiperazine
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Accession:CHEBI:46844 term browser browse the term
Synonyms:related_synonym: N-acylpiperazines


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    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19880
        chemical entity 19878
          atom 19878
            nonmetal atom 19800
              nitrogen atom 18979
                nitrogen molecular entity 18979
                  amide 17776
                    N-acylpiperazine 2506
                      (2R)-4-[(6-chloronaphthalen-2-yl)sulfonyl]-1-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbonyl]piperazine-2-carboxamide 0
                      1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid + 0
                      1-[(6-chloronaphthalen-2-yl)sulfonyl]-4-[(1-pyridin-4-ylpiperidin-4-yl)carbonyl]piperazine 0
                      1-[4-(1-oxoprop-2-enyl)-1-piperazinyl]-2-propen-1-one 0
                      1-acetyl-4-(4-\{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl\}pyridin-2-yl)piperazine 0
                      1-acetyl-4-(4-\{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy\}phenyl)piperazine + 843
                      2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanone 0
                      2-[4-(4-bromophenyl)sulfonyl-1-piperazinyl]-N-[(4-chloro-3-nitrophenyl)methylideneamino]acetamide 0
                      2-[4-(phenylmethyl)-1-piperazinyl]-N-(thiophen-2-ylmethylideneamino)acetamide 0
                      2-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-N-[3-(2-nitrophenyl)prop-2-enylideneamino]acetamide 0
                      2-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-N-(pyridin-4-ylmethylideneamino)acetamide 0
                      2-\{(2R)-4-[2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl]-1-isobutyrylpiperazin-2-yl\}-N-[2-(4-methoxyphenyl)ethyl]acetamide 0
                      3-[(2S)-3-(4-beta-alanylpiperazin-1-yl)-3-oxo-2-\{[(2,4,6-triisopropylphenyl)sulfonyl]amino\}propyl]benzenecarboximidamide 0
                      3-\{(2S)-2-[(2-naphthylsulfonyl)amino]-3-oxo-3-piperazin-1-ylpropyl\}benzenecarboximidamide 0
                      3-\{(2S)-3-(4-acetylpiperazin-1-yl)-2-[(2-naphthylsulfonyl)amino]-3-oxopropyl\}benzenecarboximidamide 0
                      4-(\{(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazin-1-yl\}carbonyl)benzonitrile 0
                      5-\{[4-(9H-fluoren-9-yl)piperazin-1-yl]carbonyl\}-1H-indole 0
                      GSK1016790A 0
                      LB42908 0
                      ML-210 0
                      N'-[(6-oxo-5-prop-2-enyl-1-cyclohexa-2,4-dienylidene)methyl]-2-[4-(phenylmethyl)-1-piperazinyl]acetohydrazide 0
                      N-(4-\{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                      N-[(2-furanylmethylamino)-oxomethyl]-2-[4-(2-phenylethenylsulfonyl)-1-piperazinyl]acetamide 0
                      N-[[3-(2-furanyl)-2-methylprop-2-enylidene]amino]-2-[4-(phenylmethyl)-1-piperazinyl]acetamide 0
                      N-carbonylpiperazine + 1142
                      N-sulfonylpiperazine + 39
                      SCH772984 33
                      SU11274 0
                      benzyl \{(1S)-5-amino-1-[(S)-hydroxy(5-\{[4-(4-phenylbutanoyl)piperazin-1-yl]methyl\}-1,2,4-oxadiazol-3-yl)methyl]pentyl\}carbamate 0
                      delavirdine + 1
                      doxazosin + 32
                      erastin 65
                      gartisertib 0
                      nigerazine A 0
                      nigerazine B 0
                      nigragillin 0
                      olaparib 58
                      pipobroman 0
                      piposulfan 0
                      smoothib 0
                      sotorasib 607
                      talmapimod 0
                      torin 1 22
                      zavegepant 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19880
        subatomic particle 19878
          composite particle 19878
            hadron 19878
              baryon 19878
                nucleon 19878
                  atomic nucleus 19878
                    atom 19878
                      main group element atom 19817
                        p-block element atom 19817
                          carbon group element atom 19757
                            carbon atom 19754
                              organic molecular entity 19754
                                organic molecule 19706
                                  organic cyclic compound 19495
                                    organic heterocyclic compound 18874
                                      organic heteromonocyclic compound 17795
                                        piperazines 5039
                                          N-acylpiperazine 2506
                                            (2R)-4-[(6-chloronaphthalen-2-yl)sulfonyl]-1-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbonyl]piperazine-2-carboxamide 0
                                            1-(phenanthren-2-ylcarbonyl)piperazine-2,3-dicarboxylic acid + 0
                                            1-[(6-chloronaphthalen-2-yl)sulfonyl]-4-[(1-pyridin-4-ylpiperidin-4-yl)carbonyl]piperazine 0
                                            1-[4-(1-oxoprop-2-enyl)-1-piperazinyl]-2-propen-1-one 0
                                            1-acetyl-4-(4-\{4-[(2-ethoxyphenyl)thio]-3-nitrophenyl\}pyridin-2-yl)piperazine 0
                                            1-acetyl-4-(4-\{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy\}phenyl)piperazine + 843
                                            2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanone 0
                                            2-[4-(4-bromophenyl)sulfonyl-1-piperazinyl]-N-[(4-chloro-3-nitrophenyl)methylideneamino]acetamide 0
                                            2-[4-(phenylmethyl)-1-piperazinyl]-N-(thiophen-2-ylmethylideneamino)acetamide 0
                                            2-[4-[(2-chlorophenyl)methyl]-1-piperazinyl]-N-[3-(2-nitrophenyl)prop-2-enylideneamino]acetamide 0
                                            2-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-N-(pyridin-4-ylmethylideneamino)acetamide 0
                                            2-\{(2R)-4-[2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl]-1-isobutyrylpiperazin-2-yl\}-N-[2-(4-methoxyphenyl)ethyl]acetamide 0
                                            3-[(2S)-3-(4-beta-alanylpiperazin-1-yl)-3-oxo-2-\{[(2,4,6-triisopropylphenyl)sulfonyl]amino\}propyl]benzenecarboximidamide 0
                                            3-\{(2S)-2-[(2-naphthylsulfonyl)amino]-3-oxo-3-piperazin-1-ylpropyl\}benzenecarboximidamide 0
                                            3-\{(2S)-3-(4-acetylpiperazin-1-yl)-2-[(2-naphthylsulfonyl)amino]-3-oxopropyl\}benzenecarboximidamide 0
                                            4-(\{(2R,5S)-2,5-dimethyl-4-[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]piperazin-1-yl\}carbonyl)benzonitrile 0
                                            5-\{[4-(9H-fluoren-9-yl)piperazin-1-yl]carbonyl\}-1H-indole 0
                                            GSK1016790A 0
                                            LB42908 0
                                            ML-210 0
                                            N'-[(6-oxo-5-prop-2-enyl-1-cyclohexa-2,4-dienylidene)methyl]-2-[4-(phenylmethyl)-1-piperazinyl]acetohydrazide 0
                                            N-(4-\{1-[4-(4-acetylpiperazin-1-yl)-trans-cyclohexyl]-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl\}-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide 0
                                            N-[(2-furanylmethylamino)-oxomethyl]-2-[4-(2-phenylethenylsulfonyl)-1-piperazinyl]acetamide 0
                                            N-[[3-(2-furanyl)-2-methylprop-2-enylidene]amino]-2-[4-(phenylmethyl)-1-piperazinyl]acetamide 0
                                            N-carbonylpiperazine + 1142
                                            N-sulfonylpiperazine + 39
                                            SCH772984 33
                                            SU11274 0
                                            benzyl \{(1S)-5-amino-1-[(S)-hydroxy(5-\{[4-(4-phenylbutanoyl)piperazin-1-yl]methyl\}-1,2,4-oxadiazol-3-yl)methyl]pentyl\}carbamate 0
                                            delavirdine + 1
                                            doxazosin + 32
                                            erastin 65
                                            gartisertib 0
                                            nigerazine A 0
                                            nigerazine B 0
                                            nigragillin 0
                                            olaparib 58
                                            pipobroman 0
                                            piposulfan 0
                                            smoothib 0
                                            sotorasib 607
                                            talmapimod 0
                                            torin 1 22
                                            zavegepant 0
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