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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:poly(ethylene glycol)
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Accession:CHEBI:46793 term browser browse the term
Definition:A polymer composed of repeating ethyleneoxy units.
Synonyms:related_synonym: 1,2-ethanediol homopolymer;   Formula=(C2H4O)n.H2O;   Macrogol;   PEG;   PEO;   POE;   Polyaethylenglykol;   Polyaethylenglykole;   alpha,omega-hydroxypoly(ethylene oxide);   alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl);   alpha-hydro-omega-hydroxypoly(oxyethylene);   ethylene glycol homopolymer;   ethylene glycol polymer;   poly(ethyleneoxide);   poly(oxyethylene);   polyethylene glycol;   polyethylene glycols;   polyethylene oxide;   polyoxyethylene
 alt_id: CHEBI:53230
 xref: Beilstein:8197326;   CAS:25322-68-3;   Wikipedia:Polyethylene_glycol


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Nonidet P-40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arnt aryl hydrocarbon receptor nuclear translocator decreases expression ISO Nonidet P-40 results in decreased expression of ARNT mRNA CTD PMID:26552463 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Nonidet P-40 results in increased expression of ATF4 mRNA CTD PMID:26552463 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Nonidet P-40 results in increased expression of ATF6 mRNA CTD PMID:26552463 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Nonidet P-40 results in increased expression of ATF6B mRNA CTD PMID:26552463 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Atg12 autophagy related 12 increases expression ISO Nonidet P-40 results in increased expression of ATG12 mRNA CTD PMID:26552463 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atg5 autophagy related 5 decreases expression ISO Nonidet P-40 results in decreased expression of ATG5 mRNA CTD PMID:26552463 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 decreases expression ISO Nonidet P-40 results in decreased expression of ATG7 mRNA CTD PMID:26552463 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Nonidet P-40 results in decreased expression of ATR mRNA CTD PMID:26552463 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Nonidet P-40 results in increased expression of BBC3 mRNA CTD PMID:26552463 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Becn1 beclin 1 increases expression ISO Nonidet P-40 results in increased expression of BECN1 mRNA CTD PMID:26552463 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression ISO Nonidet P-40 results in increased expression of BID mRNA CTD PMID:26552463 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Nonidet P-40 results in increased expression of BNIP3L mRNA CTD PMID:26552463 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Calr calreticulin decreases expression ISO Nonidet P-40 results in decreased expression of CALR mRNA CTD PMID:26552463 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car9 carbonic anhydrase 9 decreases expression ISO Nonidet P-40 results in decreased expression of CA9 mRNA CTD PMID:26552463 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp1 caspase 1 decreases expression ISO Nonidet P-40 results in decreased expression of CASP1 mRNA CTD PMID:26552463 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Nonidet P-40 results in increased expression of CCL2 mRNA CTD PMID:26552463 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Nonidet P-40 results in increased expression of CDKN1A mRNA CTD PMID:26552463 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Nonidet P-40 results in increased expression of CHEK2 mRNA CTD PMID:26552463 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Crp C-reactive protein increases expression ISO Nonidet P-40 results in increased expression of CRP mRNA CTD PMID:26552463 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of DDB2 mRNA CTD PMID:26552463 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Nonidet P-40 results in increased expression of DDIT3 mRNA CTD PMID:26552463 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Nonidet P-40 results in increased expression of DNAJC3 mRNA CTD PMID:26552463 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Epo erythropoietin decreases expression ISO Nonidet P-40 results in decreased expression of EPO mRNA CTD PMID:26552463 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Nonidet P-40 results in increased expression of GADD45A mRNA CTD PMID:26552463 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO Nonidet P-40 results in decreased expression of GCLC mRNA CTD PMID:26552463 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Nonidet P-40 results in increased expression of GCLM mRNA CTD PMID:26552463 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Grb2 growth factor receptor bound protein 2 decreases expression ISO Nonidet P-40 results in decreased expression of GRB2 mRNA CTD PMID:26552463 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Nonidet P-40 results in increased expression of HMOX1 mRNA CTD PMID:26552463 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO Nonidet P-40 results in increased expression of HSP90AA1 mRNA CTD PMID:26552463 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression ISO Nonidet P-40 results in increased expression of HSPA4 mRNA CTD PMID:26552463 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like increases expression ISO Nonidet P-40 results in increased expression of HSPA4L mRNA CTD PMID:26552463 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Nonidet P-40 results in decreased expression of HSPA5 mRNA CTD PMID:26552463 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Nonidet P-40 results in increased expression of HUS1 mRNA CTD PMID:26552463 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Ifng interferon gamma decreases expression ISO Nonidet P-40 results in decreased expression of IFNG mRNA CTD PMID:26552463 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO Nonidet P-40 results in decreased expression of IL1A mRNA CTD PMID:26552463 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il6 interleukin 6 increases expression ISO Nonidet P-40 results in increased expression of IL6 mRNA CTD PMID:26552463 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Nonidet P-40 results in decreased expression of LDHA mRNA CTD PMID:26552463 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Nonidet P-40 results in increased expression of MCL1 mRNA CTD PMID:26552463 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Nonidet P-40 results in decreased expression of MMP9 mRNA CTD PMID:26552463 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease increases expression ISO Nonidet P-40 results in increased expression of MRE11A mRNA CTD PMID:26552463 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Nbn nibrin increases expression ISO Nonidet P-40 results in increased expression of NBN mRNA CTD PMID:26552463 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Nonidet P-40 results in increased expression of NQO1 mRNA CTD PMID:26552463 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Nonidet P-40 results in decreased expression of PARP1 mRNA CTD PMID:26552463 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Rad17 RAD17 checkpoint clamp loader component increases expression ISO Nonidet P-40 results in increased expression of RAD17 mRNA CTD PMID:26552463 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072 		JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Nonidet P-40 results in decreased expression of RAD51 mRNA CTD PMID:26552463 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A increases expression ISO Nonidet P-40 results in increased expression of RAD9A mRNA CTD PMID:26552463 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Nonidet P-40 results in decreased expression of SERPINE1 mRNA CTD PMID:26552463 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Nonidet P-40 results in increased expression of SLC2A1 mRNA CTD PMID:26552463 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO Nonidet P-40 results in decreased expression of SQSTM1 mRNA CTD PMID:26552463 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Nonidet P-40 results in decreased expression of TLR4 mRNA CTD PMID:26552463 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF10A mRNA CTD PMID:26552463 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO Nonidet P-40 results in decreased expression of TNFRSF1A mRNA CTD PMID:26552463 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Nonidet P-40 results in decreased expression of TP53 mRNA CTD PMID:26552463 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Nonidet P-40 results in decreased expression of TXN mRNA CTD PMID:26552463 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Nonidet P-40 results in increased expression of TXNRD1 mRNA CTD PMID:26552463 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 decreases expression ISO Nonidet P-40 results in decreased expression of ULK1 mRNA CTD PMID:26552463 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO Nonidet P-40 results in decreased expression of VEGFA mRNA CTD PMID:26552463 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression ISO Nonidet P-40 results in decreased expression of XPC mRNA CTD PMID:26552463 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
polysorbate 40 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression ISO polysorbate 40 results in increased expression of HMOX1 mRNA CTD PMID:17225922 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
Triton X-100 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnfn cornifelin increases expression ISO Octoxynol results in increased expression of CNFN mRNA; Octoxynol results in increased expression of CNFN protein CTD PMID:25377654 NCBI chr 1:80,949,699...80,953,747
Ensembl chr 1:80,951,600...80,953,747 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Octoxynol results in increased expression of EGR1 mRNA CTD PMID:25377654 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ezr ezrin increases expression ISO Octoxynol results in increased expression of EZR mRNA CTD PMID:29893927 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Octoxynol results in decreased expression of FN1 mRNA CTD PMID:25377654 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO Octoxynol results in increased secretion of IL1A protein CTD PMID:23999410 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Octoxynol results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G LOC120100208 small nucleolar RNA SNORA71 decreases expression ISO Octoxynol results in decreased expression of SNORA71D mRNA CTD PMID:25377654 NCBI chr 1:232,131,169...232,131,300
Ensembl chr 1:232,131,169...232,131,300 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Octoxynol results in increased expression of SCD mRNA CTD PMID:29155129 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP Octoxynol inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:17038422 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      atom 19872
        nonmetal atom 19794
          oxygen atom 19535
            oxygen molecular entity 19535
              organooxygen compound 19184
                ether 17306
                  polyether 1090
                    hydroxypolyether 67
                      poly(ethylene glycol) 66
                        3,6,9,12,15,18-Hexaoxadotriacontan-1-ol 0
                        3,6,9,12,15-Pentaoxatetracosan-1-ol 0
                        5S,6S-epoxy-15R-hydroxy-ETE 0
                        Tetraethylene glycol monododecyl ether 0
                        Triethylene glycol monobutyl ether 0
                        decaethylene glycol 0
                        dodecaethylene glycol 0
                        heptacosaethylene glycol + 0
                        heptaethylene glycol 0
                        hexaethylene glycol + 0
                        nonaethylene glycol + 0
                        octaethylene glycol + 0
                        pentaethylene glycol + 0
                        poly(ethylene glycol diacrylate) 0
                        poly(ethylene glycol dimethacrylate) 0
                        poly(ethylene glycol) derivative + 66
                        poly(ethylene glycol) methyl ether methacrylate 0
                        tetradecaethylene glycol 0
                        tetraethylene glycol + 0
                        tetratriacontaethylene glycol + 0
                        triethylene glycol + 0
                        undecaethylene glycol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  ether 17306
                                    polyether 1090
                                      hydroxypolyether 67
                                        poly(ethylene glycol) 66
                                          3,6,9,12,15,18-Hexaoxadotriacontan-1-ol 0
                                          3,6,9,12,15-Pentaoxatetracosan-1-ol 0
                                          5S,6S-epoxy-15R-hydroxy-ETE 0
                                          Tetraethylene glycol monododecyl ether 0
                                          Triethylene glycol monobutyl ether 0
                                          decaethylene glycol 0
                                          dodecaethylene glycol 0
                                          heptacosaethylene glycol + 0
                                          heptaethylene glycol 0
                                          hexaethylene glycol + 0
                                          nonaethylene glycol + 0
                                          octaethylene glycol + 0
                                          pentaethylene glycol + 0
                                          poly(ethylene glycol diacrylate) 0
                                          poly(ethylene glycol dimethacrylate) 0
                                          poly(ethylene glycol) derivative + 66
                                          poly(ethylene glycol) methyl ether methacrylate 0
                                          tetradecaethylene glycol 0
                                          tetraethylene glycol + 0
                                          tetratriacontaethylene glycol + 0
                                          triethylene glycol + 0
                                          undecaethylene glycol 0
paths to the root