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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quartz
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Accession:CHEBI:46727 term browser browse the term
Synonyms:related_synonym: Formula=O2Si;   Quarz;   Tiefquarz;   alpha-quartz;   silicon oxide
 xref: CAS:14808-60-7;   KEGG:C16459
 xref_mesh: MESH:D011791


show annotations for term's descendants           Sort by:
quartz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 increases expression
multiple interactions		 EXP Quartz results in increased expression of ACOD1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of ACOD1 mRNA]		 CTD PMID:32976597 NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression		 ISO [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA]; FOSL1 promotes the reaction [Quartz results in decreased expression of ACTA2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of ACTA2 protein]
Quartz results in increased expression of ACTA2 mRNA; Quartz results in increased expression of ACTA2 protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; Nicotine promotes the reaction [Quartz results in increased expression of ACTA2 protein]		 CTD PMID:27381660 PMID:35499148 PMID:36053221 PMID:36868510 PMID:37399107 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions		 ISO Quartz results in increased phosphorylation of AKT1 protein
FOSL1 promotes the reaction [Quartz results in increased phosphorylation of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased phosphorylation of AKT1 protein]		 CTD PMID:35499148 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin increases expression ISO Quartz results in increased expression of ALB protein CTD PMID:27917503 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression
decreases expression		 ISO Quartz results in increased expression of ALDH1A1 protein
Quartz results in decreased expression of ALDH1A1 mRNA		 CTD PMID:27917503 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Anxa5 annexin A5 increases expression ISO Quartz results in increased expression of ANXA5 protein CTD PMID:20085295 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa7 annexin A7 decreases expression ISO Quartz results in decreased expression of ANXA7 protein CTD PMID:27917503 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Arg1 arginase 1 increases expression EXP Quartz results in increased expression of ARG1 mRNA CTD PMID:19836432 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 decreases expression ISO Quartz results in decreased expression of ARMCX1 protein CTD PMID:27917503 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression		 ISO ATF3 protein affects the reaction [Quartz results in increased secretion of IL1B protein]; ATF3 protein affects the reaction [Quartz results in increased secretion of IL6 protein]; ATF3 protein affects the reaction [Quartz results in increased secretion of TNF protein]
Quartz results in increased expression of ATF3 mRNA		 CTD PMID:29102675 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 affects expression EXP Quartz affects the expression of ATP1B1 mRNA CTD PMID:19836432 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 affects expression EXP Quartz affects the expression of ATP6V1B2 mRNA CTD PMID:19836432 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Auh AU RNA binding methylglutaconyl-CoA hydratase increases expression ISO Quartz results in increased expression of AUH protein CTD PMID:27917503 NCBI chr17:12,329,522...12,424,882
Ensembl chr17:12,329,524...12,424,896 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO PSMB9 inhibits the reaction [Quartz results in increased expression of BAX protein] CTD PMID:35506645 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 ISO [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; PSMB9 inhibits the reaction [Quartz results in decreased expression of BCL2 protein] CTD PMID:27381660 PMID:35506645 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of BDNF protein CTD PMID:36868510 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bpifb1 BPI fold containing family B, member 1 multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of BPIFB1 mRNA] CTD PMID:32976597 NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP Quartz results in increased expression of C2CD4B mRNA CTD PMID:19836432 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328 		JBrowse link
G C4bpa complement component 4 binding protein, alpha increases expression EXP Quartz results in increased expression of C4BPA mRNA CTD PMID:19836432 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G Capg capping actin protein, gelsolin like affects expression EXP Quartz affects the expression of CAPG mRNA CTD PMID:19836432 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Casp12 caspase 12 increases expression ISO Quartz results in increased expression of CASP12 protein CTD PMID:29729927 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases cleavage		 ISO Quartz results in increased expression of CASP3 protein
PSMB9 inhibits the reaction [Quartz results in increased cleavage of CASP3 protein]		 CTD PMID:29729927 PMID:35506645 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions
decreases expression		 ISO CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Quartz results in increased secretion of TNF protein]
Quartz results in decreased expression of CAT mRNA		 CTD PMID:19298665 PMID:27917503 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions		 ISO Quartz results in decreased expression of CAV1 mRNA; Quartz results in decreased expression of CAV1 protein
CAV1 protein modified form inhibits the reaction [Quartz affects the localization of YAP1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of COL1A1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of FN1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of GLS protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of YAP1 protein]		 CTD PMID:36053221 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP Quartz results in increased expression of CCL17 mRNA CTD PMID:19836432 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions		 EXP
ISO		 Quartz results in increased expression of CCL2 mRNA
Quartz results in increased secretion of CCL2 protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CCL2 mRNA]; Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of CCL2 protein]		 CTD PMID:19836432 PMID:27381660 PMID:32976597 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression EXP Quartz results in increased expression of CCL3 mRNA CTD PMID:19836432 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Quartz results in increased expression of CCL5 mRNA CTD PMID:27917503 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression
multiple interactions		 EXP Quartz results in increased expression of CCL7 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CCL7 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccna2 cyclin A2 increases expression EXP Quartz results in increased expression of CCNA2 mRNA CTD PMID:19836432 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Cd177 CD177 molecule increases expression
multiple interactions		 EXP Quartz results in increased expression of CD177 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CD177 mRNA]		 CTD PMID:32976597 NCBI chr 1:80,340,034...80,360,599
Ensembl chr 1:80,340,034...80,360,621 		JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions		 ISO Quartz results in decreased expression of CDH1 protein
[MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of CDH1 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of CDH1 protein]
[Nicotine co-treated with Quartz] results in increased expression of CDH1 protein		 CTD PMID:35499148 PMID:36868510 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of CDH2 protein; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of CDH2 protein] CTD PMID:36868510 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO Quartz results in decreased expression of CDKN1A mRNA CTD PMID:27917503 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ceacam4 CEA cell adhesion molecule 4 increases expression EXP Quartz results in increased expression of CEACAM10 mRNA CTD PMID:19836432 NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915 		JBrowse link
G Cfi complement factor I increases expression
multiple interactions		 EXP Quartz results in increased expression of CFI mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CFI mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression EXP Quartz results in increased expression of CH25H mRNA CTD PMID:19836432 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chia chitinase, acidic increases expression
multiple interactions		 EXP Quartz results in increased expression of CHIA mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CHIA mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 2:193,614,374...193,656,532
Ensembl chr 2:193,614,114...193,656,533 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
increases expression		 ISO Quartz results in decreased expression of COL1A1 mRNA
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of COL1A1 protein]		 CTD PMID:27381660 PMID:36053221 PMID:37399107 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions
increases expression		 ISO Nicotine promotes the reaction [Quartz results in increased expression of COL1A2 protein] CTD PMID:36868510 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Cpb2 carboxypeptidase B2 increases expression EXP Quartz results in increased expression of CPB2 mRNA CTD PMID:19836432 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Cpne5 copine 5 increases expression
multiple interactions		 EXP Quartz results in increased expression of CPNE5 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CPNE5 mRNA]		 CTD PMID:32976597 NCBI chr20:7,206,742...7,289,309
Ensembl chr20:7,206,742...7,288,883 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Quartz results in increased expression of CSF2 mRNA CTD PMID:27917503 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 increases expression ISO Quartz results in increased expression of CSTF1 protein CTD PMID:27917503 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300 		JBrowse link
G Ctsk cathepsin K increases expression EXP Quartz results in increased expression of CTSK mRNA CTD PMID:19836432 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Quartz results in increased expression of CXCL1 mRNA CTD PMID:19836432 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion
multiple interactions		 EXP Quartz results in increased secretion of CXCL10 protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of CXCL10 protein]		 CTD PMID:32976597 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions
increases expression		 EXP [Quartz results in increased abundance of Hydrogen Peroxide] which results in increased expression of CXCL2 mRNA; Rotenone inhibits the reaction [Quartz results in increased expression of CXCL2 mRNA] CTD PMID:11764986 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression
multiple interactions		 EXP Quartz results in increased expression of CXCL6 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of CXCL6 mRNA]		 CTD PMID:32976597 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO Quartz results in decreased expression of CYP1A1 mRNA CTD PMID:27917503 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression EXP Quartz results in decreased expression of CYP2E1 mRNA CTD PMID:19836432 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Quartz results in increased expression of DDIT3 mRNA CTD PMID:27917503 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO Quartz results in decreased expression of DNMT3A mRNA CTD PMID:27917503 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO Quartz results in decreased expression of DNMT3B mRNA CTD PMID:27917503 NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases expression ISO Quartz results in decreased expression of ECE1 mRNA CTD PMID:27917503 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 decreases expression ISO Quartz results in decreased expression of EDN1 mRNA CTD PMID:27917503 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn3 endothelin 3 decreases expression ISO Quartz results in decreased expression of EDN3 mRNA CTD PMID:27917503 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093 		JBrowse link
G Ednra endothelin receptor type A decreases expression ISO Quartz results in decreased expression of EDNRA mRNA CTD PMID:27917503 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Egf epidermal growth factor increases secretion
multiple interactions		 EXP Quartz results in increased secretion of EGF protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of EGF protein]		 CTD PMID:32976597 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egr1 early growth response 1 decreases expression ISO Quartz results in decreased expression of EGR1 mRNA CTD PMID:27917503 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Quartz results in decreased expression of EPHX1 mRNA CTD PMID:27917503 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit decreases expression ISO Quartz results in decreased expression of ERCC3 mRNA CTD PMID:27917503 NCBI chr18:23,883,613...23,914,326
Ensembl chr18:23,883,580...23,914,329 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression EXP Quartz results in increased expression of FABP4 mRNA CTD PMID:19836432 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Quartz results in increased expression of FCGR2B mRNA CTD PMID:19836432 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression
multiple interactions		 ISO Quartz results in increased expression of FGF7 protein
Nicotine promotes the reaction [Quartz results in increased expression of FGF7 protein]		 CTD PMID:36868510 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgg fibrinogen gamma chain increases expression EXP Quartz results in increased expression of FGG mRNA CTD PMID:19836432 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression ISO Quartz results in decreased expression of FMO5 mRNA CTD PMID:27917503 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693 		JBrowse link
G Fn1 fibronectin 1 multiple interactions
increases expression		 ISO [Ascorbic Acid co-treated with Quartz] results in increased expression of FN1 mRNA
Quartz results in increased expression of FN1 mRNA; Quartz results in increased expression of FN1 protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of FN1 protein]; Nicotine promotes the reaction [Quartz results in increased expression of FN1 protein]		 CTD PMID:27381660 PMID:36053221 PMID:36477571 PMID:36868510 PMID:37399107 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Quartz results in increased expression of [JUN protein binds to FOS protein] CTD PMID:37399107 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of ACTA2 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of CDH1 protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of PTEN protein]; FOSL1 promotes the reaction [Quartz results in decreased expression of TP53 protein]; FOSL1 promotes the reaction [Quartz results in increased expression of SNAI2 protein]; FOSL1 promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in increased phosphorylation of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 mRNA]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 protein]
Quartz results in increased expression of FOSL1 mRNA; Quartz results in increased expression of FOSL1 protein		 CTD PMID:35499148 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 affects expression ISO Quartz affects the expression of FSCN1 protein CTD PMID:27917503 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity		 ISO Glutathione inhibits the reaction [Quartz results in decreased activity of G6PDX protein] CTD PMID:18370412 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Quartz results in increased expression of GADD45A mRNA CTD PMID:27917503 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Glrx3 glutaredoxin 3 decreases expression ISO Quartz results in decreased expression of GLRX3 protein CTD PMID:27917503 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Gls glutaminase affects expression
multiple interactions		 ISO Quartz affects the expression of GLS protein
CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of GLS protein]		 CTD PMID:36053221 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gsdmd gasdermin D multiple interactions ISO GSDMD promotes the reaction [Quartz results in increased secretion of IL1A protein] CTD PMID:36840754 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsr glutathione-disulfide reductase decreases expression ISO Quartz results in decreased expression of GSR mRNA CTD PMID:27917503 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hapln4 hyaluronan and proteoglycan link protein 4 affects expression EXP Quartz affects the expression of HAPLN4 mRNA CTD PMID:19836432 NCBI chr16:19,333,106...19,341,243
Ensembl chr16:19,333,106...19,341,243 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 EXP Quartz promotes the reaction [Curcumin results in increased expression of HMOX1 mRNA]
Quartz results in increased expression of HMOX1 mRNA		 CTD PMID:18001810 PMID:19836432 PMID:21171611 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression ISO Quartz results in increased expression of HNRNPAB protein CTD PMID:27917503 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K increases expression ISO Quartz results in increased expression of HNRNPK protein CTD PMID:27917503 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Hp haptoglobin increases expression EXP Quartz results in increased expression of HP mRNA CTD PMID:19836432 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Quartz results in increased expression of HSPA1A mRNA CTD PMID:27917503 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Quartz results in decreased expression of HSPA2 mRNA; Quartz results in decreased expression of HSPA2 protein CTD PMID:27917503 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Quartz results in increased expression of HSPA6 mRNA CTD PMID:27917503 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression ISO Quartz results in increased expression of HSPD1 protein CTD PMID:27917503 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO Quartz results in increased expression of HTRA2 protein CTD PMID:27917503 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Quartz results in increased expression of ICAM1 mRNA CTD PMID:27381660 PMID:27917503 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions ISO IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; IFNG protein promotes the reaction [Quartz results in increased secretion of TNF protein]
Quartz results in increased expression of and results in increased secretion of IFNG protein		 CTD PMID:19298665 PMID:29729927 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il18 interleukin 18 increases secretion
multiple interactions		 EXP Quartz results in increased secretion of IL18 protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of IL18 protein]		 CTD PMID:32976597 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha increases expression
increases import
multiple interactions		 ISO Quartz results in increased expression of IL1A mRNA
Quartz results in increased import of IL1A protein
Cytochalasin D inhibits the reaction [Quartz results in increased import of IL1A protein]; Cytochalasin D promotes the reaction [Quartz results in increased secretion of IL1A protein]; GSDMD promotes the reaction [Quartz results in increased secretion of IL1A protein]; N-(4-(N-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide inhibits the reaction [Quartz results in increased secretion of IL1A protein]; Quartz results in increased expression of and results in increased secretion of IL1A protein		 CTD PMID:36840754 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases secretion
decreases expression
multiple interactions		 ISO Quartz results in increased secretion of IL1B protein
Quartz results in decreased expression of IL1B mRNA
ATF3 protein affects the reaction [Quartz results in increased secretion of IL1B protein]		 CTD PMID:19697923 PMID:27917503 PMID:29102675 PMID:35499148 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression EXP Quartz results in increased expression of IL1R2 mRNA CTD PMID:19836432 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Quartz results in increased expression of IL1RL1 mRNA; Quartz results in increased expression of IL1RL1 protein CTD PMID:37399107 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il33 interleukin 33 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of IL33 protein; Quartz results in increased expression of and results in increased secretion of IL33 protein CTD PMID:36868510 PMID:37399107 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression		 ISO Quartz results in increased secretion of IL6 protein
ATF3 protein affects the reaction [Quartz results in increased secretion of IL6 protein]; Quartz results in increased expression of and results in increased secretion of IL6 protein
Quartz results in increased expression of IL6 mRNA		 CTD PMID:29102675 PMID:29729927 PMID:36477571 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgam integrin subunit alpha M increases expression EXP Quartz results in increased expression of ITGAM mRNA CTD PMID:19836432 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 increases expression EXP Quartz results in increased expression of ITIH1 mRNA CTD PMID:19836432 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 decreases expression ISO Quartz results in decreased expression of JARID2 protein CTD PMID:27917503 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Quartz results in increased expression of [JUN protein binds to FOS protein] CTD PMID:37399107 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kng1 kininogen 1 multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of KNG1 mRNA] CTD PMID:32976597 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Krt18 keratin 18 decreases expression ISO Quartz results in decreased expression of KRT18 protein CTD PMID:27917503 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt7 keratin 7 increases expression ISO Quartz results in increased expression of KRT7 protein CTD PMID:27917503 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Lcn2 lipocalin 2 increases expression EXP Quartz results in increased expression of LCN2 mRNA CTD PMID:19836432 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Cytochalasin D inhibits the reaction [Quartz results in increased activity of and results in increased secretion of LDHA protein]; Quartz results in increased activity of and results in increased secretion of LDHA protein CTD PMID:36840754 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Lpo lactoperoxidase multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of LPO mRNA] CTD PMID:32976597 NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535 		JBrowse link
G Mal2 mal, T-cell differentiation protein 2 affects expression EXP Quartz affects the expression of MAL2 mRNA CTD PMID:19836432 NCBI chr 7:85,900,453...85,933,433
Ensembl chr 7:85,900,453...85,933,429 		JBrowse link
G Mir101a microRNA 101a decreases expression EXP Quartz results in decreased expression of MIR101A mRNA CTD PMID:23208435 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir126a microRNA 126a decreases expression EXP Quartz results in decreased expression of MIR126A mRNA CTD PMID:23208435 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir138-1 microRNA 138-1 increases expression EXP Quartz results in increased expression of MIR138-1 mRNA CTD PMID:23208435 NCBI chr 8:122,300,966...122,301,064
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir140 microRNA 140 decreases expression EXP Quartz results in decreased expression of MIR140 mRNA CTD PMID:23208435 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir141 microRNA 141 increases expression EXP Quartz results in increased expression of MIR141 mRNA CTD PMID:23208435 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332 		JBrowse link
G Mir144 microRNA 144 decreases expression EXP Quartz results in decreased expression of MIR144 mRNA CTD PMID:23208435 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir145 microRNA 145 decreases expression EXP Quartz results in decreased expression of MIR145 mRNA CTD PMID:23208435 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir146a microRNA 146a increases expression EXP Quartz results in increased expression of MIR146A mRNA CTD PMID:23208435 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir146b microRNA 146b increases expression EXP Quartz results in increased expression of MIR146B mRNA CTD PMID:23208435 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir17 microRNA 17 increases expression EXP Quartz results in increased expression of MIR17 mRNA CTD PMID:23208435 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir183 microRNA 183 increases expression EXP Quartz results in increased expression of MIR183 mRNA CTD PMID:23208435 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir200b microRNA 200b decreases expression EXP Quartz results in decreased expression of MIR200B mRNA CTD PMID:23208435 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir204 microRNA 204 increases expression EXP Quartz results in increased expression of MIR204 mRNA CTD PMID:23208435 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir22 microRNA 22 increases expression EXP Quartz results in increased expression of MIR22 mRNA CTD PMID:23208435 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir25 microRNA 25 decreases expression EXP Quartz results in decreased expression of MIR25 mRNA CTD PMID:23208435 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015 		JBrowse link
G Mir26a microRNA 26a decreases expression EXP Quartz results in decreased expression of MIR26A mRNA CTD PMID:23208435 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir26b microRNA 26b decreases expression EXP Quartz results in decreased expression of MIR26B mRNA CTD PMID:23208435 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680 		JBrowse link
G Mir28 microRNA 28 decreases expression EXP Quartz results in decreased expression of MIR28 mRNA CTD PMID:23208435 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608 		JBrowse link
G Mir299b microRNA 299b increases expression EXP Quartz results in increased expression of MIR299 mRNA CTD PMID:23208435 NCBI chr 6:128,723,635...128,723,752
Ensembl chr 6:128,723,635...128,723,752 		JBrowse link
G Mir300 microRNA 300 increases expression EXP Quartz results in increased expression of MIR300 mRNA CTD PMID:23208435 NCBI chr 6:128,738,513...128,738,591
Ensembl chr 6:128,738,505...128,738,594 		JBrowse link
G Mir30a microRNA 30a decreases expression EXP Quartz results in decreased expression of MIR30A mRNA CTD PMID:23208435 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir30d microRNA 30d decreases expression EXP Quartz results in decreased expression of MIR30D mRNA CTD PMID:23208435 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472 		JBrowse link
G Mir30e microRNA 30e decreases expression EXP Quartz results in decreased expression of MIR30E mRNA CTD PMID:23208435 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323 		JBrowse link
G Mir322 microRNA 322 decreases expression EXP Quartz results in decreased expression of MIR322 mRNA CTD PMID:23208435 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir345 microRNA 345 decreases expression EXP Quartz results in decreased expression of MIR345 mRNA CTD PMID:23208435 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir34c microRNA 34c multiple interactions
decreases expression		 ISO [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in decreased expression of CDH1 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of ACTA2 protein]; [MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of CDH1 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of PTEN protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of TP53 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of ACTA2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of AKT1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 mRNA]; MIR34C inhibits the reaction [Quartz results in increased expression of FOSL1 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of SNAI2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in increased phosphorylation of AKT1 protein]
Quartz results in decreased expression of MIR34C		 CTD PMID:35499148 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Quartz results in decreased expression of MIR352 mRNA CTD PMID:23208435
G Mir375 microRNA 375 decreases expression EXP Quartz results in decreased expression of MIR375 mRNA CTD PMID:23208435 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir96 microRNA 96 increases expression EXP Quartz results in increased expression of MIR96 mRNA CTD PMID:23208435 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Mir98 microRNA 98 decreases expression EXP Quartz results in decreased expression of MIR98 mRNA CTD PMID:23208435 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mir99a microRNA 99a decreases expression EXP Quartz results in decreased expression of MIR99A mRNA CTD PMID:23208435 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Quartz results in decreased expression of MIRLET7D mRNA CTD PMID:23208435 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of MKI67 protein CTD PMID:36868510 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Quartz results in increased expression of MMP1 mRNA CTD PMID:27381660 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression
multiple interactions		 EXP Quartz results in increased expression of MMP12 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of MMP12 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Msr1 macrophage scavenger receptor 1 increases expression EXP Quartz results in increased expression of MSR1 mRNA CTD PMID:19836432 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676 		JBrowse link
G Mt1 metallothionein 1 decreases expression ISO Quartz results in decreased expression of MT1A mRNA CTD PMID:27917503 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Quartz results in increased expression of MYC mRNA CTD PMID:27917503 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO Quartz results in increased expression of NFAT5 mRNA CTD PMID:27917503 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675 		JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression EXP Quartz results in increased expression of NOXO1 mRNA CTD PMID:19836432 NCBI chr10:13,723,253...13,726,008
Ensembl chr10:13,721,473...13,726,061 		JBrowse link
G Npm1 nucleophosmin 1 affects response to substance ISO NPM1 affects the susceptibility to Quartz CTD PMID:37399107 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Nicotine co-treated with Quartz] results in increased phosphorylation of NTRK2 protein; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of NTRK2 protein] CTD PMID:36868510 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Quartz results in decreased expression of OGG1 mRNA CTD PMID:27917503 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Orm1 orosomucoid 1 multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of ORM1 mRNA] CTD PMID:32976597 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression
increases expression		 ISO Quartz results in decreased expression of PDHB mRNA
Quartz results in increased expression of PDHB protein		 CTD PMID:27917503 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 decreases expression ISO Quartz results in decreased expression of PGK1 protein CTD PMID:27917503 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pkm pyruvate kinase M1/2 affects expression ISO Quartz affects the expression of PKM protein CTD PMID:27917503 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Plaur plasminogen activator, urokinase receptor affects expression EXP Quartz affects the expression of PLAUR mRNA CTD PMID:19836432 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO Quartz results in increased expression of PRDX1 mRNA CTD PMID:27917503 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO Quartz results in decreased expression of PRDX2 mRNA CTD PMID:27917503 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx5 peroxiredoxin 5 affects expression EXP Quartz affects the expression of PRDX5 mRNA CTD PMID:19836432 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268 		JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression ISO Quartz results in decreased expression of PRDX6 protein CTD PMID:27917503 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression
multiple interactions		 ISO Quartz results in decreased expression of PSMB9 mRNA; Quartz results in decreased expression of PSMB9 protein; Quartz results in decreased expression of PSMB9 SNP
PSMB9 inhibits the reaction [Quartz results in decreased expression of BCL2 protein]; PSMB9 inhibits the reaction [Quartz results in increased cleavage of CASP3 protein]; PSMB9 inhibits the reaction [Quartz results in increased expression of BAX protein]		 CTD PMID:35506645 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression		 ISO FOSL1 promotes the reaction [Quartz results in decreased expression of PTEN protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of PTEN protein] CTD PMID:35499148 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Quartz results in decreased expression of PTGS1 mRNA CTD PMID:27917503 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP
ISO		 [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Curcumin inhibits the reaction [Quartz results in increased expression of PTGS2 mRNA]
Quartz results in increased expression of PTGS2 mRNA; Quartz results in increased expression of PTGS2 protein
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 mRNA; [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein		 CTD PMID:17222177 PMID:18001810 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rbm4 RNA binding motif protein 4 increases expression ISO Quartz results in increased expression of RBM4 protein CTD PMID:27917503 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP Quartz results in increased expression of S100A9 mRNA CTD PMID:19836432 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression
multiple interactions		 EXP Quartz results in increased expression of SCN10A mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SCN10A mRNA]		 CTD PMID:32976597 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Sdf2l1 stromal cell-derived factor 2-like 1 affects expression EXP Quartz affects the expression of SDF2L1 mRNA CTD PMID:19836432 NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902 		JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component affects expression ISO Quartz affects the expression of SEC13 protein CTD PMID:27917503 NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173 		JBrowse link
G Semg1 semenogelin 1 increases expression ISO Quartz results in increased expression of SEMG1 mRNA CTD PMID:27917503 NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882 		JBrowse link
G Serpina10 serpin family A member 10 increases expression EXP Quartz results in increased expression of SERPINA10 mRNA CTD PMID:19836432 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544 		JBrowse link
G Sftpc surfactant protein C multiple interactions ISO [Nicotine co-treated with Quartz] results in increased expression of SFTPC protein CTD PMID:36868510 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Slc26a4 solute carrier family 26 member 4 increases expression
multiple interactions		 EXP Quartz results in increased expression of SLC26A4 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SLC26A4 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703 		JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression ISO Quartz results in increased expression of SNAI1 protein CTD PMID:36868510 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 multiple interactions
increases expression		 ISO FOSL1 promotes the reaction [Quartz results in increased expression of SNAI2 protein]; MIR34C inhibits the reaction [Quartz results in increased expression of SNAI2 protein] CTD PMID:35499148 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP Quartz results in increased expression of SOD2 mRNA CTD PMID:19836432 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions		 EXP Quartz results in increased expression of SPP1 mRNA
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of SPP1 mRNA]		 CTD PMID:19836432 PMID:32976597 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation		 ISO Nicotine inhibits the reaction [Quartz results in decreased phosphorylation of STAT3 protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased phosphorylation of STAT3 protein] CTD PMID:36868510 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tcp1 t-complex 1 affects expression ISO Quartz affects the expression of TCP1 protein CTD PMID:27917503 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tfrc transferrin receptor increases expression EXP Quartz results in increased expression of TFRC mRNA CTD PMID:19836432 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases secretion ISO Quartz results in increased secretion of TGFB1 protein CTD PMID:35499148 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 increases expression EXP Quartz results in increased expression of TGFBR1 mRNA CTD PMID:19836432 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 increases expression EXP Quartz results in increased expression of TIAM1 mRNA CTD PMID:19836432 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO [Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA CTD PMID:27381660 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmem45b transmembrane protein 45b multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of TMEM45B mRNA] CTD PMID:32976597 NCBI chr 8:29,865,276...29,910,453
Ensembl chr 8:29,865,278...29,910,453 		JBrowse link
G Tmem72 transmembrane protein 72 multiple interactions
increases expression		 EXP Tobacco Smoke Pollution promotes the reaction [Quartz results in increased expression of TMEM72 mRNA] CTD PMID:32976597 NCBI chr 4:149,946,296...149,973,550
Ensembl chr 4:149,948,257...149,973,550 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases activity
increases secretion		 ISO
EXP		 Ascorbic Acid promotes the reaction [Quartz results in increased expression of TNF mRNA]; Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]]; Butylated Hydroxytoluene inhibits the reaction [Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; CAT protein inhibits the reaction [Quartz results in increased secretion of TNF protein]; Dextran Sulfate promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Dextran Sulfate promotes the reaction [Quartz results in increased secretion of TNF protein]; IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; IFNG protein promotes the reaction [Quartz results in increased secretion of TNF protein]; Mannitol inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]; Mannitol inhibits the reaction [Quartz results in increased secretion of TNF protein]
aluminum lactate inhibits the reaction [Quartz results in increased expression of TNF mRNA]
Quartz results in increased activity of TNF protein
ATF3 protein affects the reaction [Quartz results in increased secretion of TNF protein]; Quartz results in increased expression of and results in increased secretion of TNF protein		 CTD PMID:11306444 PMID:18803060 PMID:19298665 PMID:19697923 PMID:19836432 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Quartz results in decreased expression of TNFSF10 mRNA CTD PMID:27917503 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 increases expression
increases mutagenesis
decreases expression
multiple interactions		 EXP
ISO		 Quartz results in increased expression of TRP53 protein
Quartz results in increased mutagenesis of TRP53 protein
Quartz results in decreased expression of TP53 mRNA; Quartz results in decreased expression of TP53 protein
FOSL1 promotes the reaction [Quartz results in decreased expression of TP53 protein]; MIR34C inhibits the reaction [Quartz results in decreased expression of TP53 protein]		 CTD PMID:11306444 PMID:27917503 PMID:35499148 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpi1 triosephosphate isomerase 1 decreases expression ISO Quartz results in decreased expression of TPI1 protein CTD PMID:27917503 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 increases expression EXP Quartz results in increased expression of TREM2 mRNA CTD PMID:19836432 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Tuba1c tubulin, alpha 1C affects expression ISO Quartz affects the expression of TUBA1C protein CTD PMID:27917503 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression
multiple interactions		 ISO Quartz results in increased expression of TWIST1 protein
Nicotine promotes the reaction [Quartz results in increased expression of TWIST1 protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of TWIST1 protein]		 CTD PMID:36868510 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Vcp valosin-containing protein affects expression ISO Quartz affects the expression of VCP protein CTD PMID:27917503 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases secretion		 ISO
EXP		 [Ascorbic Acid co-treated with Quartz] results in increased expression of VEGFA mRNA
Quartz results in increased secretion of VEGFA protein
Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of VEGFA protein]		 CTD PMID:27381660 PMID:32976597 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vim vimentin increases expression
multiple interactions		 ISO Quartz results in increased expression of VIM protein
[MIR34C binds to FOSL1 3' UTR] promotes the reaction [Quartz results in increased expression of VIM protein]; FOSL1 promotes the reaction [Quartz results in increased expression of VIM protein]; MIR34C inhibits the reaction [Quartz results in increased expression of VIM protein]
Nicotine promotes the reaction [Quartz results in increased expression of VIM protein]; staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of VIM protein]		 CTD PMID:35499148 PMID:36868510 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator affects expression
multiple interactions
affects localization		 ISO Quartz affects the expression of YAP1 protein
CAV1 protein modified form inhibits the reaction [Quartz affects the localization of YAP1 protein]; CAV1 protein modified form inhibits the reaction [Quartz results in increased expression of YAP1 protein]		 CTD PMID:36053221 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon affects expression ISO Quartz affects the expression of YWHAE protein CTD PMID:27917503 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589 		JBrowse link
G Zfp866 zinc finger protein 866 increases expression EXP Quartz results in increased expression of CXCL5 mRNA CTD PMID:19836432 NCBI chr16:19,653,966...19,675,968
Ensembl chr16:19,668,258...19,675,932 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19922
    chemical entity 19920
      chemical substance 14412
        mineral 4325
          oxide mineral 197
            quartz 198
Path 2
Term Annotations click to browse term
  CHEBI ontology 19922
    subatomic particle 19892
      composite particle 19892
        hadron 19920
          baryon 19892
            nucleon 19920
              atomic nucleus 19892
                atom 19892
                  main group element atom 19866
                    p-block element atom 19866
                      p-block molecular entity 19866
                        chalcogen molecular entity 19615
                          oxygen molecular entity 19587
                            oxide 12763
                              inorganic oxide 7783
                                silicon oxide 5606
                                  silicon dioxide 5609
                                    quartz 198
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