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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carbonate salt
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Accession:CHEBI:46721 term browser browse the term
Synonyms:related_synonym: carbonate salts


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calcium carbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein decreases expression ISO Calcium Carbonate results in decreased expression of BGLAP protein CTD PMID:2027271 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Capn1 calpain 1 increases activity ISO Calcium Carbonate analog results in increased activity of CAPN1 protein CTD PMID:24412303 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Casp3 caspase 3 increases activity ISO Calcium Carbonate analog results in increased activity of CASP3 protein CTD PMID:24412303 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Calcium Carbonate analog results in increased expression of DDIT3 CTD PMID:24412303 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Pth parathyroid hormone affects expression
decreases expression		 ISO Calcium Carbonate affects the expression of PTH protein
Calcium Carbonate results in decreased expression of PTH protein		 CTD PMID:1752077 PMID:2027271 PMID:3826069 PMID:7891547 PMID:8481062 More... NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression ISO Calcium Carbonate results in decreased expression of PTHLH protein CTD PMID:16006300 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO Calcium Carbonate results in decreased expression of SPP1 protein CTD PMID:17977878 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
lithium carbonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase multiple interactions
decreases activity		 EXP Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of ALAD protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of ALAD protein]; Zinc Sulfate inhibits the reaction [Lithium Carbonate results in decreased activity of ALAD protein] CTD PMID:19083387 PMID:28988373 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Casp1 caspase 1 increases expression ISO Lithium Carbonate results in increased expression of CASP1 protein CTD PMID:34984798 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression		 EXP
ISO		 Lithium Carbonate results in increased activity of CASP3 protein
Butylated Hydroxytoluene inhibits the reaction [Lithium Carbonate results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [Lithium Carbonate results in increased activity of CASP3 protein]
Lithium Carbonate results in increased expression of CASP3 protein		 CTD PMID:27588890 PMID:34984798 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 increases expression ISO Lithium Carbonate results in increased expression of CASP6 protein CTD PMID:34984798 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp7 caspase 7 increases expression ISO Lithium Carbonate results in increased expression of CASP7 protein CTD PMID:34984798 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 increases expression ISO Lithium Carbonate results in increased expression of CASP9 protein CTD PMID:34984798 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity
multiple interactions		 EXP
ISO		 Lithium Carbonate results in decreased activity of CAT protein
Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of CAT protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of CAT protein]		 CTD PMID:28988373 PMID:34984798 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity		 EXP Lithium Carbonate promotes the reaction [sodium arsenite results in decreased activity of GSR protein]; sodium arsenite promotes the reaction [Lithium Carbonate results in decreased activity of GSR protein] CTD PMID:28988373 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA CTD PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta decreases expression
increases expression		 ISO Lithium Carbonate results in decreased expression of IL1B mRNA
Lithium Carbonate results in increased expression of IL1B mRNA; Lithium Carbonate results in increased expression of IL1B protein		 CTD PMID:29594315 PMID:34984798 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Ins1 insulin 1 decreases expression
multiple interactions		 EXP Lithium Carbonate results in decreased expression of INS1 protein
Lithium Carbonate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]		 CTD PMID:10700396 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Mir21 microRNA 21 multiple interactions EXP [Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR21 mRNA; Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR21 mRNA] CTD PMID:31928237 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir29b1 microRNA 29b-1 multiple interactions EXP [Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR29B1 mRNA; Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of MIR29B1 mRNA] CTD PMID:31928237 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation ISO Lithium Carbonate results in increased phosphorylation of NFKBIA protein CTD PMID:34984798 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 increases expression ISO Lithium Carbonate results in increased expression of NLRP3 protein CTD PMID:34984798 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions EXP [Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of NOS3 protein; Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of NOS3 protein] CTD PMID:31928237 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 decreases activity
multiple interactions		 EXP Lithium Carbonate results in decreased activity of PFKFB2 protein
Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein]		 CTD PMID:10700396 NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699 		JBrowse link
G Pla2g4a phospholipase A2 group 4A increases expression ISO Lithium Carbonate results in increased expression of PLA2G4A mRNA; Lithium Carbonate results in increased expression of PLA2G4A protein CTD PMID:17594078 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pth parathyroid hormone increases expression ISO Lithium Carbonate results in increased expression of PTH protein CTD PMID:3083797 PMID:18234408 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pycard PYD and CARD domain containing increases expression ISO Lithium Carbonate results in increased expression of PYCARD protein CTD PMID:34984798 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO Lithium Carbonate results in increased phosphorylation of RELA protein CTD PMID:34984798 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Lithium Carbonate results in increased expression of TNF mRNA; Lithium Carbonate results in increased expression of TNF protein CTD PMID:34984798 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions EXP [Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of TNNI3 protein; Acetylcysteine inhibits the reaction [[Lithium Carbonate results in increased abundance of Lithium] which results in increased expression of TNNI3 protein] CTD PMID:31928237 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19899
    chemical entity 19897
      atom 19897
        nonmetal atom 19819
          oxygen atom 19558
            oxygen molecular entity 19558
              organooxygen compound 19209
                carbonates 140
                  carbonate salt 29
                    ammonium carbonate 0
                    barium carbonate 0
                    calcium carbonate + 7
                    carbonate mineral + 0
                    ferrous carbonate 0
                    lithium carbonate 24
                    magnesium carbonate 0
                    potassium carbonate 0
                    sodium carbonate + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19899
    subatomic particle 19897
      composite particle 19897
        hadron 19897
          baryon 19897
            nucleon 19897
              atomic nucleus 19897
                atom 19897
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19776
                        carbon atom 19772
                          organic molecular entity 19772
                            heteroorganic entity 19532
                              organochalcogen compound 19293
                                organooxygen compound 19209
                                  carbon oxoacid 18678
                                    carbonic acid 6257
                                      carbonates 140
                                        carbonate salt 29
                                          ammonium carbonate 0
                                          barium carbonate 0
                                          calcium carbonate + 7
                                          carbonate mineral + 0
                                          ferrous carbonate 0
                                          lithium carbonate 24
                                          magnesium carbonate 0
                                          potassium carbonate 0
                                          sodium carbonate + 0
paths to the root