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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxadiazole
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Accession:CHEBI:46685 term browser browse the term
Synonyms:related_synonym: oxadiazoles


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1,3,4-oxadiazoles term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases activity EXP 1,3,4-oxadiazole analog results in decreased activity of CYP17A1 protein CTD PMID:25993309 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:255,476,861...255,482,974 		JBrowse link
4-phenyl-3-furoxancarbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLC mRNA
4-phenyl-3-furoxancarbonitrile analog results in increased expression of GCLC mRNA 		CTD PMID:22851183 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of NQO1 mRNA CTD PMID:22851183 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
azilsartan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of BAX protein CTD PMID:29408668 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in decreased expression of BCL2L1 protein CTD PMID:29408668 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Zinc Sulfate binds to azilsartan] which results in increased expression of CASP9 protein CTD PMID:29408668 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
GR 127935 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions EXP GR 127935 promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr15:45,005,648...45,111,416
Ensembl chr15:45,005,799...45,102,534 		JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP GR 127935 inhibits the reaction [eletriptan results in decreased expression of CALCA mRNA]; GR 127935 inhibits the reaction [Sumatriptan results in decreased expression of CALCA mRNA] CTD PMID:14715155 NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP GR 127935 binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:91,052,432...91,418,583 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP [[volinanserin binds to and results in decreased activity of HTR2A protein] which co-treated with GR 127935] results in decreased susceptibility to Methamphetamine; GR 127935 binds to and results in decreased activity of HTR2A protein CTD PMID:9109356 PMID:11751031 NCBI chr15:56,360,647...56,428,703
Ensembl chr15:56,359,596...56,431,619 		JBrowse link
GSK690693 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
increases phosphorylation 		ISO GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of AKT1 protein]; GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein]
GSK690693 results in decreased phosphorylation of AKT1 protein
GSK690693 results in increased phosphorylation of AKT1 protein 		CTD PMID:30871965 PMID:31445927 PMID:31962201 PMID:34784199 PMID:35259468 More... NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO GSK690693 results in increased expression of BBC3 protein CTD PMID:35259468 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased expression of BCL2 protein] CTD PMID:30871965 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of CASP3 protein] CTD PMID:30871965 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Ctnnb1 catenin beta 1 decreases phosphorylation ISO GSK690693 results in decreased phosphorylation of CTNNB1 protein CTD PMID:35639300 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation
multiple interactions 		ISO GSK690693 results in decreased phosphorylation of EIF4EBP1 protein
[sunitinib co-treated with GSK690693] results in decreased phosphorylation of EIF4EBP1 protein 		CTD PMID:22532600 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874 		JBrowse link
G Fas Fas cell surface death receptor affects response to substance ISO GSK690693 affects the susceptibility to FAS protein CTD PMID:31445927 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Foxo3 forkhead box O3 decreases phosphorylation ISO GSK690693 results in decreased phosphorylation of FOXO3 protein CTD PMID:35259468 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
increases expression 		ISO GSK690693 results in decreased phosphorylation of GSK3B protein
GSK690693 results in increased expression of GSK3B protein 		CTD PMID:31962201 PMID:35639300 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO GSK690693 inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of H2AX protein] CTD PMID:34784199 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein] CTD PMID:30871965 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Srsf4 serine and arginine rich splicing factor 4 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF4 protein CTD PMID:31962201 NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:149,345,422...149,374,609 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF5 protein CTD PMID:31962201 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:106,336,756...106,341,931 		JBrowse link
G Srsf6 serine and arginine rich splicing factor 6 multiple interactions ISO [SRPIN340 co-treated with GSK690693] results in decreased phosphorylation of SRSF6 protein CTD PMID:31962201 NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:172,009,061...172,014,392 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO GSK690693 promotes the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein] CTD PMID:30871965 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Tnf tumor necrosis factor increases response to substance ISO GSK690693 results in increased susceptibility to TNF protein CTD PMID:31445927 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tsc2 TSC complex subunit 2 multiple interactions
decreases phosphorylation 		ISO [sunitinib co-treated with GSK690693] results in decreased phosphorylation of TSC2 protein
GSK690693 results in decreased phosphorylation of TSC2 protein 		CTD PMID:22532600 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:14,125,680...14,160,600 		JBrowse link
molsidomine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxn frataxin increases expression ISO Molsidomine results in increased expression of FXN mRNA CTD PMID:23418481 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:231,300,150...231,323,989 		JBrowse link
G Ptgis prostaglandin I2 synthase multiple interactions EXP Molsidomine inhibits the reaction [Hypoxia increases expression of Ptgis mRNA in the lung] RGD PMID:12062720 RGD:401959327 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Molsidomine inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Molsidomine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:21641380 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
opicapone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO opicapone results in decreased activity of UGT1A1 protein CTD PMID:35810997 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO opicapone results in decreased activity of UGT1A9 protein CTD PMID:35810997 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          nitrogen atom 19595
            nitrogen molecular entity 19595
              organonitrogen compound 19403
                organonitrogen heterocyclic compound 18546
                  oxadiazole 34
                    1,2,4-oxadiazole + 7
                    1,2,5-oxadiazole + 20
                    1,3,4-oxadiazoles + 1
                    1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester 0
                    1-[3-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-1-butanone 0
                    1-ethyl-4-[[methyl-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone 0
                    2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamide 0
                    2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                    2-(4-methoxyphenyl)-N-[4-[5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                    2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzamide 0
                    2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    3-(2-chlorophenyl)-N-cyclohexyl-5-methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-4-isoxazolecarboxamide 0
                    3-(2-methoxy-6-methyl-3-pyridinyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                    3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester 0
                    3-(4-Chlorophenyl)-5-(4,5-dihydro-1H-imidazol-2-ylsulfanylmethyl)-1,2,4-oxadiazole 0
                    3-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole 0
                    3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole 0
                    3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole 0
                    3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole 0
                    3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamide 0
                    3-[3-(4-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                    3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methylphenyl)propanamide 0
                    3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-cyclopropylpropanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-methylpropanamide 0
                    3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole 0
                    3-phenyl-5-thioxo-2,5-dihydro-1,2,3-oxadiazol-3-ium 0
                    4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-morpholinyl-[4-[3-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone 0
                    5-(2,3-dihydrobenzofuran-5-yl)-3-(4-fluorophenyl)-1,2,4-oxadiazole 0
                    5-(2-chloro-4-fluorophenyl)-3-(2-pyrazinyl)-1,2,4-oxadiazole 0
                    5-(2-ethoxyphenyl)-3-(2-methoxy-6-methyl-3-pyridinyl)-1,2,4-oxadiazole 0
                    5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                    5-(3,5-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole 0
                    5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(5-bromo-2-chlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(6-chloro-3-pyridinyl)-3-(3-methoxyphenyl)-1,2,4-oxadiazole 0
                    5-[(4-methyl-1-piperidinyl)methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-[4-phenyl-5-(trifluoromethyl)-2-thiophenyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 0
                    5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamide 0
                    AZD1979 + 0
                    AZD1979 oxetane hydrolysis product 0
                    Avagacestat 0
                    CYM5442 0
                    N,2-dimethyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-3-furancarboxamide 0
                    N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine 0
                    N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamide 0
                    N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-(2,3,5-trimethylphenoxy)acetamide 0
                    N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide 0
                    N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide 0
                    N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamide 0
                    N-ethyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-ethyl-N-(2-ethylphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-methyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-tert-butyl-2-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzamide 0
                    [2-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-(1-pyrrolidinyl)methanone 0
                    butalamine 0
                    imolamine 0
                    molsidomine 4
                    opicapone 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  organic heteromonocyclic compound 18212
                                    oxadiazole 34
                                      1,2,4-oxadiazole + 7
                                      1,2,5-oxadiazole + 20
                                      1,3,4-oxadiazoles + 1
                                      1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester 0
                                      1-[3-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-1-butanone 0
                                      1-ethyl-4-[[methyl-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone 0
                                      2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamide 0
                                      2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                                      2-(4-methoxyphenyl)-N-[4-[5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                                      2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzamide 0
                                      2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      3-(2-chlorophenyl)-N-cyclohexyl-5-methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-4-isoxazolecarboxamide 0
                                      3-(2-methoxy-6-methyl-3-pyridinyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                                      3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester 0
                                      3-(4-Chlorophenyl)-5-(4,5-dihydro-1H-imidazol-2-ylsulfanylmethyl)-1,2,4-oxadiazole 0
                                      3-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole 0
                                      3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole 0
                                      3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole 0
                                      3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole 0
                                      3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamide 0
                                      3-[3-(4-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                                      3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methylphenyl)propanamide 0
                                      3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-cyclopropylpropanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-methylpropanamide 0
                                      3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole 0
                                      3-phenyl-5-thioxo-2,5-dihydro-1,2,3-oxadiazol-3-ium 0
                                      4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-morpholinyl-[4-[3-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone 0
                                      5-(2,3-dihydrobenzofuran-5-yl)-3-(4-fluorophenyl)-1,2,4-oxadiazole 0
                                      5-(2-chloro-4-fluorophenyl)-3-(2-pyrazinyl)-1,2,4-oxadiazole 0
                                      5-(2-ethoxyphenyl)-3-(2-methoxy-6-methyl-3-pyridinyl)-1,2,4-oxadiazole 0
                                      5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                                      5-(3,5-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole 0
                                      5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(5-bromo-2-chlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(6-chloro-3-pyridinyl)-3-(3-methoxyphenyl)-1,2,4-oxadiazole 0
                                      5-[(4-methyl-1-piperidinyl)methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-[4-phenyl-5-(trifluoromethyl)-2-thiophenyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 0
                                      5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamide 0
                                      AZD1979 + 0
                                      AZD1979 oxetane hydrolysis product 0
                                      Avagacestat 0
                                      CYM5442 0
                                      N,2-dimethyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-3-furancarboxamide 0
                                      N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine 0
                                      N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamide 0
                                      N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-(2,3,5-trimethylphenoxy)acetamide 0
                                      N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide 0
                                      N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide 0
                                      N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamide 0
                                      N-ethyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-ethyl-N-(2-ethylphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-methyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-tert-butyl-2-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzamide 0
                                      [2-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-(1-pyrrolidinyl)methanone 0
                                      butalamine 0
                                      imolamine 0
                                      molsidomine 4
                                      opicapone 2
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