silicate mineral - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	silicate mineral	go back to main search page
Accession:	CHEBI:46663	browse the term
Synonyms:	related_synonym:	Silikat; Silikate; Silikatminerale; silicate minerals; silicates; silicato; silicatos

show annotations for term's descendants Sort by:
Rat (3768 ) Mouse (3896 ) Human (3962 ) Chinchilla (0 ) Bonobo (0 ) Dog (0 ) Squirrel (0 ) Pig (4 ) Green Monkey (0) Naked Mole-rat (0 ) All
Genes (3768)

silicate mineral

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

regulator of telomere elongation helicase 1

decreases expression

EXP

silicate material inhalation decreases expression of Rtel1 mRNA in rat lung

RGD

NCBI chr 3:188,778,329...188,842,877
Ensembl chr 3:188,807,951...188,843,709

G

telomerase reverse transcriptase

increases expression

EXP

silicate material inhalation increases expression of Tert mRNA in rat lung

RGD

NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111

amosite asbestos

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

apoptosis-associated tyrosine kinase

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of AATK promoter

NCBI chr10:105,789,171...105,825,634
Ensembl chr10:105,785,469...105,825,618

G

ATP binding cassette subfamily G member 2

increases methylation

ISO

Asbestos, Amosite results in increased methylation of ABCG2 promoter

NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493

G

ABR activator of RhoGEF and GTPase

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ABR promoter

NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467

G

aconitate decarboxylase 1

decreases expression

ISO

Asbestos, Amosite results in decreased expression of ACOD1 mRNA

NCBI chr15:86,286,531...86,295,803
Ensembl chr15:86,286,579...86,295,687

G

AKT serine/threonine kinase 1

increases activity

ISO

Asbestos, Amosite results in increased activity of AKT1 protein

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

ankyrin repeat domain containing 11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ANKRD11 promoter

NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491

G

ankyrin repeat domain 52

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ANKRD52 promoter

NCBI chr 7:1,390,730...1,410,139
Ensembl chr 7:1,391,325...1,407,410

G

anoctamin 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ANO1 promoter

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

Rho guanine nucleotide exchange factor 17

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ARHGEF17 promoter

NCBI chr 1:164,642,690...164,702,241
Ensembl chr 1:164,642,690...164,702,241

G

Rho/Rac guanine nucleotide exchange factor 18

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ARHGEF18 promoter

NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997

G

Rho guanine nucleotide exchange factor 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ARHGEF4 promoter

NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550

G

arrestin domain containing 3

increases methylation

ISO

Asbestos, Amosite results in increased methylation of ARRDC3 promoter

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875

G

autophagy related 16-like 2

increases methylation

ISO

Asbestos, Amosite results in increased methylation of ATG16L2 promoter

NCBI chr 1:165,100,946...165,123,307
Ensembl chr 1:165,102,936...165,115,473

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

decreases expression

ISO

Asbestos, Amosite results in decreased expression of ATP12A mRNA

NCBI chr15:34,559,209...34,583,866
Ensembl chr15:34,559,209...34,583,866

G

ATPase secretory pathway Ca2+ transporting 2

increases expression

ISO

Asbestos, Amosite results in increased expression of ATP2C2 mRNA

NCBI chr19:64,662,729...64,719,998
Ensembl chr19:64,662,715...64,719,996

G

aurora kinase C

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of AURKC promoter

NCBI chr 1:75,876,773...75,882,893
Ensembl chr 1:75,876,773...75,897,426

G

BARX homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of BARX1 promoter

NCBI chr17:16,196,764...16,200,239
Ensembl chr17:16,196,764...16,200,239

G

BCL2 associated X, apoptosis regulator

multiple interactions
affects localization

ISO

pifithrin inhibits the reaction [Asbestos, Amosite affects the localization of BAX protein]

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

Bcl2-like 1

multiple interactions

ISO

BCL2L1 protein inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]; BCL2L1 protein inhibits the reaction [Asbestos, Amosite results in increased expression of XBP1 protein alternative form]

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

bestrophin 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of BEST1 promoter

NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974

G

bestrophin 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of BEST4 promoter

NCBI chr 5:135,858,774...135,865,624
Ensembl chr 5:135,860,018...135,863,707

G

basic helix-loop-helix family, member a9

decreases expression

ISO

Asbestos, Amosite results in decreased expression of BHLHA9 mRNA

NCBI chr10:62,011,787...62,012,908
Ensembl chr10:62,011,787...62,012,908

G

brain specific homeobox

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of BSX promoter

NCBI chr 8:50,151,204...50,154,960
Ensembl chr 8:50,151,204...50,154,960

G

BUB1 mitotic checkpoint serine/threonine kinase

increases expression

ISO

Asbestos, Amosite results in increased expression of BUB1 mRNA

NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921

G

calcium/calmodulin-dependent protein kinase IV

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CAMK4 promoter

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

caspase 3

increases activity
multiple interactions

ISO

Asbestos, Amosite results in increased activity of CASP3 protein
Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein]; Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP3 protein]

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 9

multiple interactions
increases activity

EXP
ISO

pifithrin inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]; Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased activity of CASP9 protein]

PMID:12540492 PMID:14766669 PMID:16357363

Ensembl chr 5:159,391,188...159,409,648

G

catalase

multiple interactions

ISO

CAT protein inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cadherin 16

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDH16 promoter

NCBI chr19:367,202...377,710
Ensembl chr19:367,274...388,934

G

cadherin 22

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDH22 promoter

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

cadherin 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDH3 promoter

NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257

G

cadherin 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDH6 promoter

NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287

G

cadherin 7

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDH7 promoter

NCBI chr13:27,186,223...27,336,076
Ensembl chr13:27,187,257...27,336,023

G

cyclin-dependent kinase 18

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDK18 promoter

NCBI chr13:46,107,763...46,140,705
Ensembl chr13:46,108,911...46,140,865

G

cyclin-dependent kinase inhibitor 1A

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDKN1A gene

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 2A

increases methylation
multiple interactions
decreases expression

ISO

Asbestos, Amosite results in increased methylation of CDKN2A exon
Asbestos, Amosite results in increased susceptibility to [NF2 protein mutant form co-treated with CDKN2A protein mutant form co-treated with TRP53 protein mutant form]
Asbestos, Amosite results in decreased expression of CDKN2A mRNA; Asbestos, Amosite results in decreased expression of CDKN2A mRNA alternative form; Asbestos, Amosite results in decreased expression of CDKN2A protein; Asbestos, Amosite results in decreased expression of CDKN2A protein alternative form

PMID:29112861 PMID:37441092

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

caudal type homeo box 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of CDX2 promoter

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

cms1 ribosomal small subunit homolog

decreases expression

ISO

Asbestos, Amosite results in decreased expression of CMSS1 mRNA

NCBI chr11:56,403,620...56,701,751
Ensembl chr11:56,403,499...56,701,755

G

CCR4-NOT transcription complex subunit 9

increases methylation

ISO

Asbestos, Amosite results in increased methylation of CNOT9 promoter

NCBI chr 9:83,533,369...83,558,207
Ensembl chr 9:83,533,369...83,558,197

G

collagen type I alpha 1 chain

multiple interactions
increases expression

EXP

benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]; Iron promotes the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]; tetramethylthiourea inhibits the reaction [Asbestos, Amosite results in increased expression of COL1A1 mRNA]

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

C-X-C motif chemokine ligand 1

increases expression

EXP

Asbestos, Amosite results in increased expression of CXCL1 protein

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

CXXC finger protein 1

increases methylation

ISO

Asbestos, Amosite results in increased methylation of CXXC1 promoter

NCBI chr18:70,088,407...70,093,786
Ensembl chr18:70,088,460...70,093,778

G

doublecortin-like kinase 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of DCLK1 promoter

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090

G

DNA-damage inducible transcript 3

increases expression

ISO

Asbestos, Amosite results in increased expression of DDIT3 mRNA

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DENN domain containing 3

increases methylation

ISO

Asbestos, Amosite results in increased methylation of DENND3 promoter

NCBI chr 7:107,304,860...107,362,573
Ensembl chr 7:107,220,192...107,362,573

G

distal-less homeobox 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of DLX4 promoter

NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,582,303...80,587,294

G

DM1 protein kinase

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of DMPK promoter

NCBI chr 1:87,858,294...87,868,624
Ensembl chr 1:87,858,316...87,868,910

G

epidermal growth factor receptor

increases expression
decreases phosphorylation

EXP
ISO

Asbestos, Amosite results in increased expression of EGFR mRNA
Asbestos, Amosite results in decreased phosphorylation of EGFR protein

PMID:15626777 PMID:22251266

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

empty spiracles homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of EMX1 promoter

NCBI chr 4:119,282,692...119,300,822
Ensembl chr 4:119,282,692...119,300,817

G

engrailed homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of EN2 promoter

NCBI chr 4:7,954,953...7,960,793
Ensembl chr 4:7,954,953...7,960,793

G

endoplasmic reticulum to nucleus signaling 1

increases expression
multiple interactions

ISO
EXP

Asbestos, Amosite results in increased expression of ERN1 mRNA; Asbestos, Amosite results in increased expression of ERN1 protein
4-phenylbutyric acid inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]; BCL2L1 protein inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]; EUK-134 inhibits the reaction [Asbestos, Amosite results in increased expression of ERN1 protein]

NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791

G

endoplasmic reticulum to nucleus signaling 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ERN2 promoter

NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:186,157,691...186,174,521

G

extended synaptotagmin 3

increases expression

ISO

Asbestos, Amosite results in increased expression of ESYT3 mRNA

NCBI chr 8:108,749,761...108,796,630
Ensembl chr 8:108,750,489...108,796,572

G

even-skipped homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of EVX1 promoter

NCBI chr 4:82,747,192...82,751,569
Ensembl chr 4:82,746,993...82,751,569

G

even-skipped homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of EVX2 promoter

NCBI chr 3:79,965,630...79,969,700
Ensembl chr 3:79,965,630...79,969,305

G

family with sequence similarity 72, member A

increases methylation

ISO

Asbestos, Amosite results in increased methylation of FAM72A promoter

NCBI chr13:45,519,940...45,531,322
Ensembl chr13:45,519,818...45,531,324

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FARP1 promoter

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

FAT atypical cadherin 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FAT3 promoter

NCBI chr 8:20,972,840...21,555,679
Ensembl chr 8:20,972,840...21,555,240

G

fucose kinase

increases methylation

ISO

Asbestos, Amosite results in increased methylation of FCSK promoter

NCBI chr19:55,743,746...55,783,873
Ensembl chr19:55,739,842...55,800,496

G

forkhead box D2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXD2 promoter

NCBI chr 5:133,664,760...133,667,483
Ensembl chr 5:133,664,760...133,667,483

G

forkhead box E3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXE3 promoter

NCBI chr 5:133,681,684...133,683,266
Ensembl chr 5:133,681,702...133,683,266

G

forkhead box G1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXG1 promoter

NCBI chr 6:72,401,582...72,404,392
Ensembl chr 6:72,394,239...72,427,392

G

forkhead box I1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXI1 promoter

NCBI chr10:19,310,466...19,314,405
Ensembl chr10:19,310,482...19,314,405

G

forkhead box I2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXI2 promoter

NCBI chr 1:199,652,703...199,656,503
Ensembl chr 1:199,652,703...199,656,498

G

forkhead box K1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXK1 promoter

NCBI chr12:17,223,599...17,288,564
Ensembl chr12:17,229,430...17,288,564

G

forkhead box L1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXL1 promoter

NCBI chr19:66,105,953...66,109,366

G

forkhead box N3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FOXN3 promoter

NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040

G

FXYD domain-containing ion transport regulator 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FXYD1 promoter

NCBI chr 1:95,414,556...95,418,645
Ensembl chr 1:95,414,557...95,418,591

G

FXYD domain-containing ion transport regulator 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of FXYD6 promoter

NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715

G

glucose-6-phosphate dehydrogenase

decreases activity
multiple interactions

ISO

Asbestos, Amosite results in decreased activity of G6PD protein
Glutathione inhibits the reaction [Asbestos, Amosite results in decreased activity of G6PD protein]

PMID:14613721 PMID:18370412

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

cyclin G associated kinase

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of GAK promoter

NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974

G

goosecoid homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of GSC2 promoter

NCBI chr11:96,576,424...96,578,412
Ensembl chr11:96,575,600...96,578,412

G

GTF2I repeat domain containing 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of GTF2IRD1 promoter

NCBI chr12:27,890,594...27,997,506
Ensembl chr12:27,890,675...27,997,494

G

HCK proto-oncogene, Src family tyrosine kinase

increases activity

ISO

Asbestos, Amosite results in increased activity of HCK protein

NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:162,031,817...162,074,935

G

H2.0-like homeobox

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HLX promoter

NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264

G

homeobox A10

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA10 promoter

NCBI chr 4:82,662,204...82,671,490
Ensembl chr 4:82,662,204...82,665,922

G

homeobox A11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA11 promoter

NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:82,673,140...82,676,844

G

homeo box A13

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA13 promoter

NCBI chr 4:82,689,566...82,691,701
Ensembl chr 4:82,689,566...82,691,701

G

homeobox A3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA3 promoter

NCBI chr 4:82,599,860...82,643,831
Ensembl chr 4:82,599,860...82,643,831

G

homeo box A4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA4 promoter

NCBI chr 4:82,620,294...82,622,302
Ensembl chr 4:82,620,299...82,622,302

G

homeobox A6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA6 promoter

NCBI chr 4:82,637,024...82,639,463

G

homeobox A9

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXA9 promoter

NCBI chr 4:82,653,847...82,659,958
Ensembl chr 4:82,653,825...82,662,093

G

homeo box B1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB1 promoter

NCBI chr10:81,827,915...81,830,404
Ensembl chr10:81,827,915...81,830,404

G

homeo box B3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB3 promoter

NCBI chr10:81,786,001...81,810,655
Ensembl chr10:81,795,882...81,809,628

G

homeo box B5

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB5 promoter

NCBI chr10:81,765,911...81,768,119

G

homeo box B6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB6 promoter

NCBI chr10:81,755,263...81,763,999

G

homeo box B7

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB7 promoter

NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,749,097...81,752,550

G

homeo box B8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB8 promoter

NCBI chr10:81,745,430...81,747,181
Ensembl chr10:81,739,704...81,747,802

G

homeo box B9

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXB9 promoter

NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872

G

homeobox C11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXC11 promoter

NCBI chr 7:135,969,707...135,973,222
Ensembl chr 7:135,969,989...135,973,222

G

homeo box C4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXC4 promoter

NCBI chr 7:136,049,059...136,051,601
Ensembl chr 7:136,049,059...136,051,601

G

homeo box C5

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXC5 promoter

NCBI chr 7:136,029,454...136,032,876
Ensembl chr 7:136,029,454...136,032,876

G

homeobox D11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXD11 promoter

NCBI chr 3:79,992,394...79,994,688
Ensembl chr 3:79,992,394...79,994,688

G

homeo box D12

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXD12 promoter

NCBI chr 3:79,985,106...79,986,227
Ensembl chr 3:79,985,106...79,986,227

G

homeo box D4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXD4 promoter

NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948

G

homeobox D8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HOXD8 promoter

NCBI chr 3:80,015,223...80,017,789
Ensembl chr 3:80,014,735...80,018,765

G

hippocalcin-like 1

increases methylation

ISO

Asbestos, Amosite results in increased methylation of HPCAL1 gene

NCBI chr 6:46,206,809...46,313,364
Ensembl chr 6:46,260,494...46,313,353

G

heat shock transcription factor 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of HSF4 promoter

NCBI chr19:50,057,331...50,068,134
Ensembl chr19:50,057,672...50,063,404

G

heat shock protein family A (Hsp70) member 5

increases expression

ISO

Asbestos, Amosite results in increased expression of HSPA5 mRNA; Asbestos, Amosite results in increased expression of HSPA5 protein

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

interleukin 1 beta

increases expression
increases secretion

EXP
ISO

Asbestos, Amosite results in increased expression of IL1B protein
Asbestos, Amosite results in increased secretion of IL1B protein
Asbestos, Amosite results in increased expression of IL1B mRNA

PMID:8473757 PMID:27083413

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

increases expression

ISO

Asbestos, Amosite results in increased expression of IL6 mRNA

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

IQ motif and ubiquitin domain containing

increases methylation

ISO

Asbestos, Amosite results in increased methylation of IQUB promoter

NCBI chr 4:53,897,336...53,962,279
Ensembl chr 4:53,897,332...53,954,925

G

iroquois homeobox 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of IRX6 promoter

NCBI chr19:30,503,416...30,509,396
Ensembl chr19:30,503,419...30,509,382

G

ISL LIM homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ISL2 promoter

NCBI chr 8:64,819,879...64,824,864
Ensembl chr 8:64,819,879...64,824,864

G

potassium inwardly-rectifying channel, subfamily J, member 6

increases expression

ISO

Asbestos, Amosite results in increased expression of KCNJ6 mRNA

NCBI chr11:47,531,312...47,778,348
Ensembl chr11:47,531,312...47,778,348

G

KLF transcription factor 3

increases methylation

ISO

Asbestos, Amosite results in increased methylation of KLF3 gene

NCBI chr14:43,828,387...43,859,418
Ensembl chr14:43,828,387...43,850,826

G

kallikrein 1-related peptidase C10

increases methylation

ISO

Asbestos, Amosite results in increased methylation of KLK3 gene

NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586

G

ladybird homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LBX2 promoter

NCBI chr 4:117,149,690...117,151,575
Ensembl chr 4:117,149,690...117,151,575

G

LCK proto-oncogene, Src family tyrosine kinase

increases activity

ISO

Asbestos, Amosite results in increased activity of LCK protein

NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267

G

LIM homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LHX2 promoter

NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645

G

LIM homeobox 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LHX3 promoter

NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:29,424,620...29,432,637

G

LIM homeobox 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LHX6 promoter

NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559

G

LIM homeobox 8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LHX8 promoter

NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:245,904,712...245,929,376

G

LIM homeobox transcription factor 1 alpha

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LMX1A promoter

NCBI chr13:82,367,493...82,511,157
Ensembl chr13:82,367,933...82,511,154

G

LSM family member 14B

increases methylation

ISO

Asbestos, Amosite results in increased methylation of LSM14B promoter

NCBI chr 3:187,503,251...187,514,041
Ensembl chr 3:187,503,045...187,512,473

G

leukocyte receptor tyrosine kinase

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of LTK promoter

NCBI chr 3:127,188,479...127,195,356
Ensembl chr 3:127,188,480...127,197,402

G

mitogen activated protein kinase kinase kinase 12

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of MAP3K12 promoter

NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137

G

mitogen-activated protein kinase kinase kinase 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of MAP3K6 promoter

NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111

G

mitogen activated protein kinase 1

increases phosphorylation
increases activity
multiple interactions

EXP
ISO

Asbestos, Amosite results in increased phosphorylation of MAPK1 protein
Asbestos, Amosite results in increased activity of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK1 protein]; Iron promotes the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK1 protein]

PMID:11306436 PMID:29112861

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

increases phosphorylation
increases activity
multiple interactions

EXP
ISO

Asbestos, Amosite results in increased phosphorylation of MAPK3 protein
Asbestos, Amosite results in increased activity of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK3 protein]; Iron promotes the reaction [Asbestos, Amosite results in increased phosphorylation of MAPK3 protein]

PMID:11306436 PMID:29112861

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

MCF.2 cell line derived transforming sequence-like

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of MCF2L promoter

NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956

G

minichromosome maintenance complex component 3 associated protein

increases methylation

ISO

Asbestos, Amosite results in increased methylation of MCM3AP promoter

NCBI chr20:12,127,060...12,164,651
Ensembl chr20:12,127,060...12,164,651

G

MAPK interacting serine/threonine kinase 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of MKNK2 promoter

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

maestro heat-like repeat family member 3

increases expression

ISO

Asbestos, Amosite results in increased expression of MROH3 mRNA

NCBI chr13:50,181,713...50,217,164
Ensembl chr13:50,181,713...50,217,164

G

myosin light chain kinase 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of MYLK3 promoter

NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

multiple interactions

ISO

Asbestos, Amosite results in increased susceptibility to [NF2 protein mutant form co-treated with CDKN2A protein mutant form co-treated with TRP53 protein mutant form]

NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151

G

nuclear factor I X

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of NFIX promoter

NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092

G

NFKB inhibitor delta

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of NFKBID promoter

NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861

G

neuronal guanine nucleotide exchange factor

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of NGEF promoter

NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:95,594,823...95,692,251

G

NK6 homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of NKX6-2 promoter

NCBI chr 1:203,811,582...203,813,122
Ensembl chr 1:203,811,582...203,813,122

G

notochord homeobox

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of NOTO promoter

NCBI chr 4:119,518,663...119,522,902
Ensembl chr 4:119,518,514...119,523,799

G

2'-5'-oligoadenylate synthetase 3

decreases expression

ISO

Asbestos, Amosite results in decreased expression of OAS3 mRNA

NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420

G

one cut homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ONECUT1 promoter

NCBI chr 8:84,480,066...84,507,848
Ensembl chr 8:84,480,305...84,508,124

G

orthopedia homeobox

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of OTP promoter

NCBI chr 2:27,842,892...27,851,093
Ensembl chr 2:27,842,897...27,851,093

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases activity

ISO

3-aminobenzamide inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]; [Smoke analog co-treated with Asbestos, Amosite] results in increased activity of PARP1 protein; CAT protein inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]; Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased activity of PARP1 protein]

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

protocadherin related 15

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDH15 promoter

NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958

G

protocadherin 8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDH8 promoter

NCBI chr15:61,607,521...61,612,090
Ensembl chr15:61,607,521...61,612,097

G

protocadherin alpha 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA1 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 10

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA10 promoter

G

protocadherin alpha 11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA11 promoter

G

protocadherin alpha 13

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA13 promoter

G

protocadherin alpha 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA3 promoter

G

protocadherin alpha 5

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA5 promoter

G

protocadherin alpha 6

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA6 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 7

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA7 promoter

G

protocadherin alpha 8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHA8 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha subfamily C, 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHAC1 promoter

G

protocadherin alpha subfamily C, 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHAC2 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin gamma subfamily A, 10

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA10 promoter

NCBI chr18:29,825,926...29,919,095

G

protocadherin gamma subfamily A, 11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA11 promoter

NCBI chr18:29,834,606...29,919,095

G

protocadherin gamma subfamily A, 12

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA12 promoter

NCBI chr18:29,843,897...29,919,095

G

protocadherin gamma subfamily A, 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA3 promoter

NCBI chr18:29,750,383...29,919,095

G

protocadherin gamma subfamily A, 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA4 promoter

NCBI chr18:29,760,777...29,794,877

G

protocadherin gamma subfamily A, 5

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA5 promoter

NCBI chr18:29,770,940...29,919,095

G

protocadherin gamma subfamily A, 7

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA7 promoter

NCBI chr18:29,794,252...29,919,095

G

protocadherin gamma subfamily A, 8

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGA8 promoter

NCBI chr18:29,805,113...29,919,095

G

protocadherin gamma subfamily B, 7

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PCDHGB7 promoter

NCBI chr18:29,830,362...29,919,098
Ensembl chr18:29,799,669...29,919,101

G

platelet derived growth factor subunit A

multiple interactions
decreases expression
increases expression

EXP

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA]; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA]; Iron promotes the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA]; tetramethylthiourea inhibits the reaction [Asbestos, Amosite results in increased expression of PDGFA mRNA]
Asbestos, Amosite results in decreased expression of PDGFA mRNA

PMID:11306436 PMID:12475806 PMID:21797767

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

increases expression

ISO

Asbestos, Amosite results in increased expression of PIK3CG mRNA

NCBI chr 6:54,494,247...54,529,563
Ensembl chr 6:54,478,603...54,529,509

G

pleckstrin homology and RhoGEF domain containing G5

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PLEKHG5 promoter

NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229

G

POTE ankyrin domain family member 1 like 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of ANKRD30A promoter

NCBI chr 3:118,095,804...118,281,502
Ensembl chr 3:118,098,764...118,281,536

G

POU class 2 homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of POU2F2 promoter

NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564

G

protein kinase AMP-activated catalytic subunit alpha 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PRKAA2 promoter

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324

G

paired related homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of PRRX2 promoter

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:34,520,173...34,566,284

G

serine protease 3

increases methylation

ISO

Asbestos, Amosite results in increased methylation of PRSS3 gene

NCBI chr 4:71,169,749...71,173,223
Ensembl chr 4:71,169,749...71,173,223

G

protein tyrosine kinase 2

increases activity

ISO

Asbestos, Amosite results in increased activity of PTK2 protein

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091

G

receptor-interacting serine-threonine kinase 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of RIPK3 promoter

NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025

G

ring finger protein 146

increases methylation

ISO

Asbestos, Amosite results in increased methylation of RNF146 promoter

NCBI chr 1:30,286,680...30,304,367
Ensembl chr 1:30,287,511...30,304,361

G

ribosomal protein S27a

decreases expression

ISO

Asbestos, Amosite results in decreased expression of RPS27A mRNA

NCBI chr14:107,486,664...107,488,941
Ensembl chr 5:138,465,088...138,466,080
Ensembl chr14:138,465,088...138,466,080
Ensembl chr 5:138,465,088...138,466,080

G

ribosomal protein S6

increases expression

EXP

Asbestos, Amosite results in increased expression of RPS6 protein modified form

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566

G

SATB homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of SATB2 promoter

NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:65,844,570...66,021,238

G

Sbds, ribosome maturation factor

increases methylation

ISO

Asbestos, Amosite results in increased methylation of SBDS promoter

NCBI chr12:32,056,649...32,065,816
Ensembl chr12:32,056,518...32,065,813

G

serine active site containing 1

increases methylation

ISO

Asbestos, Amosite results in increased methylation of SERAC1 promoter

NCBI chr 1:49,025,845...49,061,853
Ensembl chr 1:49,025,845...49,061,853

G

serum/glucocorticoid regulated kinase 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of SGK1 promoter

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231

G

solute carrier organic anion transporter family, member 3a1

decreases expression

ISO

Asbestos, Amosite results in decreased expression of SLCO3A1 mRNA

NCBI chr 1:137,516,037...137,797,836
Ensembl chr 1:137,505,158...137,797,836

G

superoxide dismutase 2

multiple interactions

ISO

[Asbestos, Amosite co-treated with TNF protein] results in increased activity of SOD2 protein; [Asbestos, Amosite co-treated with TNF protein] results in increased expression of SOD2 mRNA

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

SRC proto-oncogene, non-receptor tyrosine kinase

increases activity

ISO

Asbestos, Amosite results in increased activity of SRC protein

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462

G

signal transducer and activator of transcription 3

increases expression
increases activity

EXP
ISO

Asbestos, Amosite results in increased expression of STAT3 protein modified form
Asbestos, Amosite results in increased expression of STAT3 mRNA
Asbestos, Amosite results in increased activity of STAT3 protein

PMID:27083413 PMID:29112861

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

T-box brain transcription factor 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TBR1 promoter

NCBI chr 3:66,758,805...66,769,626
Ensembl chr 3:66,759,803...66,769,626

G

T-box transcription factor 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TBX4 promoter

NCBI chr10:71,228,145...71,258,222
Ensembl chr10:71,197,727...71,258,218

G

transforming growth factor, beta 1

increases expression
multiple interactions
decreases expression

EXP

Asbestos, Amosite results in increased expression of TGFB1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA]; Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA]; Iron promotes the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA]; tetramethylthiourea inhibits the reaction [Asbestos, Amosite results in increased expression of TGFB1 mRNA]
Asbestos, Amosite results in decreased expression of TGFB1 mRNA

PMID:11306436 PMID:12475806 PMID:21797767

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

TIAM Rac1 associated GEF 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TIAM2 promoter

NCBI chr 1:46,323,450...46,524,769
Ensembl chr 1:46,323,456...46,524,769

G

TIMP metallopeptidase inhibitor 3

decreases expression

ISO

Asbestos, Amosite results in decreased expression of TIMP3 mRNA

NCBI chr 7:19,408,539...19,459,558
Ensembl chr 7:19,409,631...19,459,547

G

T-cell leukemia homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TLX2 promoter

NCBI chr 4:117,131,516...117,133,359
Ensembl chr 4:117,131,516...117,133,359

G

tumor necrosis factor

increases expression
multiple interactions
increases secretion

EXP
ISO

Asbestos, Amosite results in increased expression of TNF protein
[Asbestos, Amosite co-treated with TNF protein] results in increased activity of SOD2 protein; [Asbestos, Amosite co-treated with TNF protein] results in increased expression of SOD2 mRNA; [Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate; [Asbestos, Amosite co-treated with TNF protein] results in increased susceptibility to Vitamin K 3; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate]
Asbestos, Amosite results in increased expression of TNF mRNA
Asbestos, Amosite results in increased secretion of TNF protein

PMID:8473757 PMID:8817062 PMID:27083413

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

tumor protein p53

affects localization
multiple interactions
increases expression
increases response to substance

ISO
EXP

Asbestos, Amosite affects the localization of TP53 protein
Asbestos, Amosite results in increased susceptibility to [NF2 protein mutant form co-treated with CDKN2A protein mutant form co-treated with TRP53 protein mutant form]
Asbestos, Amosite results in increased expression of TP53 mRNA; Asbestos, Amosite results in increased expression of TP53 protein
Deferoxamine inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]; Phytic Acid inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]; pifithrin inhibits the reaction [Asbestos, Amosite affects the localization of TP53 protein]; pifithrin inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 protein]; Sodium Benzoate inhibits the reaction [Asbestos, Amosite results in increased expression of TP53 mRNA]
TP53 protein results in increased susceptibility to Asbestos, Amosite

PMID:16357363 PMID:37441092

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tweety family member 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TTYH1 promoter

NCBI chr 1:79,125,564...79,144,137
Ensembl chr 1:79,125,574...79,144,091

G

tweety family member 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TTYH2 promoter

NCBI chr10:100,208,129...100,252,505
Ensembl chr10:100,207,860...100,253,521

G

tweety family member 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of TTYH3 promoter

NCBI chr12:19,110,973...19,139,379
Ensembl chr12:19,110,824...19,139,371

G

upstream binding protein 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of UBP1 promoter

NCBI chr 8:122,748,005...122,793,824
Ensembl chr 8:122,748,049...122,793,824

G

USH1 protein network component harmonin binding protein 1

decreases expression

ISO

Asbestos, Amosite results in decreased expression of USHBP1 mRNA

NCBI chr16:18,091,311...18,101,927
Ensembl chr16:18,091,316...18,101,867

G

ubiquitin specific peptidase 37

increases methylation

ISO

Asbestos, Amosite results in increased methylation of USP37 promoter

NCBI chr 9:83,467,966...83,567,848
Ensembl chr 9:83,467,966...83,533,172

G

ventral anterior homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VAX1 promoter

NCBI chr 1:268,310,644...268,326,713
Ensembl chr 1:268,311,348...268,316,464

G

ventral anterior homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VAX2 promoter

NCBI chr 4:117,753,180...117,777,242
Ensembl chr 4:117,753,180...117,777,242

G

VENT homeobox

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VENTX promoter

NCBI chr X:90,707,273...90,708,315
Ensembl chr X:90,706,748...90,708,555

G

VRK serine/threonine kinase 3

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VRK3 promoter

NCBI chr 1:104,379,903...104,407,278
Ensembl chr 1:104,379,628...104,407,274

G

visual system homeobox 1

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VSX1 promoter

NCBI chr 3:159,974,693...159,982,292
Ensembl chr 3:159,974,693...159,982,292

G

visual system homeobox 2

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of VSX2 promoter

NCBI chr 6:109,932,943...109,972,005
Ensembl chr 6:109,948,313...109,971,100

G

WNK lysine deficient protein kinase 4

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of WNK4 promoter

NCBI chr10:86,702,828...86,719,917
Ensembl chr10:86,702,865...86,720,198

G

Wnt family member 10A

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of WNT10A promoter

NCBI chr 9:83,798,594...83,811,060
Ensembl chr 9:83,798,594...83,811,067

G

Wnt family member 11

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of WNT11 promoter

NCBI chr 1:162,545,660...162,565,456
Ensembl chr 1:162,545,680...162,564,660

G

Wnt family member 5B

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of WNT5B promoter

NCBI chr 4:154,281,852...154,406,081
Ensembl chr 4:154,281,852...154,405,681

G

Wnt family member 7A

decreases methylation

ISO

Asbestos, Amosite results in decreased methylation of WNT7A promoter

NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149

G

X-box binding protein 1

multiple interactions
increases expression

ISO

Asbestos, Amosite results in increased expression of and affects the splicing of XBP1 mRNA; BCL2L1 protein inhibits the reaction [Asbestos, Amosite results in increased expression of XBP1 protein alternative form]

NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706

G

zinc finger CW-type and PWWP domain containing 2

decreases expression

ISO

Asbestos, Amosite results in decreased expression of ZCWPW2 mRNA

NCBI chr 8:126,506,855...126,651,270
Ensembl chr 8:126,541,597...126,658,945

G

zinc finger, ZZ-type containing 3

increases methylation

ISO

Asbestos, Amosite results in increased methylation of ZZZ3 promoter

NCBI chr 2:243,990,305...244,057,251
Ensembl chr 2:243,990,289...244,056,118

amphibole asbestos

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

annexin A10

increases expression

ISO

Asbestos, Amphibole results in increased expression of ANXA10 mRNA

NCBI chr16:32,505,025...32,571,961
Ensembl chr16:32,467,126...32,571,961

G

annexin A5

increases expression

ISO

Asbestos, Amphibole results in increased expression of ANXA5 protein

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

apurinic/apyrimidinic endodeoxyribonuclease 1

affects expression

ISO

Asbestos, Amphibole affects the expression of APEX1 protein

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

apolipoprotein E

increases expression

EXP

Asbestos, Amphibole results in increased expression of APOE mRNA

NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855

G

activating transcription factor 3

increases expression

ISO

Asbestos, Amphibole results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

ATM serine/threonine kinase

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of ATM protein

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

BCL2 associated X, apoptosis regulator

affects expression

ISO

Asbestos, Amphibole affects the expression of BAX protein

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

Bcl2-like 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of BCL2L1 protein

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

complement C3

increases expression

EXP

Asbestos, Amphibole results in increased expression of C3 mRNA

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

complement C6

increases expression

EXP

Asbestos, Amphibole results in increased expression of C6 mRNA

NCBI chr 2:55,573,596...55,648,857
Ensembl chr 2:55,573,653...55,649,120

G

caspase 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of CASP1 protein

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 8

increases expression

ISO

Asbestos, Amphibole results in increased expression of CASP8 protein

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

catalase

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CAT protein

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

caveolin 1

increases expression

EXP

Asbestos, Amphibole results in increased expression of CAV1 mRNA

NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740

G

C-C motif chemokine ligand 12

increases expression

EXP

Asbestos, Amphibole results in increased expression of CCL12 mRNA

NCBI chr10:67,567,876...67,569,426
Ensembl chr10:67,567,876...67,569,426

G

C-C motif chemokine ligand 21

affects expression

ISO

Asbestos, Amphibole affects the expression of CCL21 protein

NCBI chr 5:61,776,411...61,777,515
Ensembl chr 5:61,776,413...61,777,540

G

C-C motif chemokine ligand 3

affects expression

ISO

Asbestos, Amphibole affects the expression of CCL3 protein

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 4

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CCL4 protein

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine ligand 7

increases expression

EXP

Asbestos, Amphibole results in increased expression of CCL7 mRNA

NCBI chr10:67,514,095...67,515,945
Ensembl chr10:67,514,091...67,515,947

G

cyclin C

increases expression

ISO

Asbestos, Amphibole results in increased expression of CCNC protein

NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:40,063,623...40,093,370

G

cyclin D1

increases expression

ISO

Asbestos, Amphibole results in increased expression of CCND1 protein

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin G1

affects expression

ISO

Asbestos, Amphibole affects the expression of CCNG1 protein

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

Asbestos, Amphibole results in increased expression of CDKN1A protein

PMID:20705543 PMID:20855422

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1C

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CDKN1C mRNA

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498

G

checkpoint kinase 2

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CHEK2 protein

NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667

G

calponin 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CNN1 mRNA

NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:28,908,330...28,919,482

G

collagen type I alpha 1 chain

increases expression

ISO

Asbestos, Amphibole results in increased expression of COL1A1 mRNA

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

increases expression

EXP
ISO

Asbestos, Amphibole results in increased expression of COL1A2 mRNA

PMID:19219932 PMID:22251266

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type III alpha 1 chain

increases expression

ISO
EXP

Asbestos, Amphibole results in increased expression of COL3A1 mRNA

PMID:19219932 PMID:22251266

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

crystallin, alpha B

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CRYAB protein

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

colony stimulating factor 2

increases secretion
increases expression

ISO

[Asbestos, Amphibole results in increased secretion of IL1B protein] which results in increased secretion of CSF2 protein
Asbestos, Amphibole results in increased expression of CSF2 protein

PMID:20855422 PMID:23017228

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

colony stimulating factor 3

increases secretion

ISO

Asbestos, Amphibole results in increased secretion of CSF3 protein

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860

G

cathepsin B

increases expression

EXP

Asbestos, Amphibole results in increased expression of CTSB mRNA

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

C-X-C motif chemokine ligand 1

increases expression

EXP

Asbestos, Amphibole results in increased expression of CXCL1 protein

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

increases expression

ISO

Asbestos, Amphibole results in increased expression of CXCL10 protein

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 2

increases expression
multiple interactions

ISO
EXP

Asbestos, Amphibole results in increased expression of CXCL2 mRNA
Deferoxamine promotes the reaction [Asbestos, Amphibole results in increased expression of CXCL2]; ferric chloride inhibits the reaction [Asbestos, Amphibole results in increased expression of CXCL2]
Asbestos, Amphibole results in increased expression of CXCL2; Asbestos, Amphibole results in increased expression of CXCL2 mRNA

PMID:20831825 PMID:21605006 PMID:27083413

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

increases expression

EXP

Asbestos, Amphibole results in increased expression of CXCL3 mRNA

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CYP1A1 protein

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 24, subfamily a, polypeptide 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of CYP24A1 mRNA

NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083

G

cytochrome P450, family 2, subfamily e, polypeptide 1

affects expression

ISO

Asbestos, Amphibole affects the expression of CYP2E1 protein

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450 family 7 subfamily A member 1

affects expression

ISO

Asbestos, Amphibole affects the expression of CYP7A1 protein

NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202

G

damage-specific DNA binding protein 1

affects expression

ISO

Asbestos, Amphibole affects the expression of DDB1 protein

NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596

G

DNA-damage inducible transcript 3

affects expression

ISO

Asbestos, Amphibole affects the expression of DDIT3 protein

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression

ISO

Asbestos, Amphibole results in increased expression of DNAJA1 protein

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

E2F transcription factor 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of E2F1 protein

NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563

G

epidermal growth factor receptor

increases expression

EXP

Asbestos, Amphibole results in increased expression of EGFR mRNA

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

early growth response 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of EGR1 protein

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

epoxide hydrolase 2

affects expression

ISO

Asbestos, Amphibole affects the expression of EPHX2 protein

NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

ISO

Asbestos, Amphibole results in increased expression of ERCC1 protein

NCBI chr 1:88,099,308...88,135,966
Ensembl chr 1:88,118,891...88,139,120

G

ERCC excision repair 3, TFIIH core complex helicase subunit

increases expression

ISO

Asbestos, Amphibole results in increased expression of ERCC3 protein

NCBI chr18:24,157,831...24,188,543
Ensembl chr18:24,148,084...24,190,898

G

coagulation factor VIII

increases expression

EXP

Asbestos, Amphibole results in increased expression of F8 mRNA

NCBI chr18:155,237...187,186
Ensembl chr18:155,309...186,683

G

Fas ligand

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of FASLG protein

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of FMO1 protein

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

flavin containing dimethylaniline monoxygenase 5

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of FMO5 protein

NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:187,910,964...187,938,464

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO

Asbestos, Amphibole results in increased expression of GADD45A protein

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth differentiation factor 15

affects expression

ISO

Asbestos, Amphibole affects the expression of GDF15 protein

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022

G

glutathione peroxidase 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of GPX1 protein

NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581

G

glutathione-disulfide reductase

affects expression

ISO

Asbestos, Amphibole affects the expression of GSR protein

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase, mu 5

affects expression

ISO

Asbestos, Amphibole affects the expression of GSTM3 protein

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

heme oxygenase 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HMOX1 mRNA

PMID:20831825 PMID:20855422

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

heat shock transcription factor 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSF1 protein

NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:110,076,710...110,103,665

G

heat shock protein 90 alpha family class B member 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of HSP90AB1 protein

NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:22,931,070...22,935,926

G

heat shock protein family A (Hsp70) member 1A

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPA1A protein

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1 like

affects expression

ISO

Asbestos, Amphibole affects the expression of HSPA1L protein

NCBI chr20:3,853,496...3,860,223
Ensembl chr20:3,853,331...3,876,877

G

heat shock protein family A (Hsp70) member 2

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPA2 protein

NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:100,864,553...100,867,133

G

heat shock protein family A (Hsp70) member 4

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPA4 protein

NCBI chr10:37,908,866...37,951,994
Ensembl chr10:37,908,866...37,949,835

G

heat shock protein family A (Hsp70) member 5

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of HSPA5 protein

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPA6 protein

NCBI chr13:85,805,911...85,807,052

G

heat shock protein family A (Hsp70) member 8

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of HSPA8 protein

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family B (small) member 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of HSPB1 protein

NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301

G

heat shock protein family D (Hsp60) member 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPD1 protein

NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037

G

heat shock protein family E (Hsp10) member 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPE1 protein

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

heat shock protein family H (Hsp110) member 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of HSPH1 protein

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

interferon gamma

decreases expression
increases expression

EXP
ISO

Asbestos, Amphibole results in decreased expression of IFNG protein
Asbestos, Amphibole results in increased expression of IFNG protein

PMID:27083413 PMID:28870655

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

insulin-like growth factor binding protein 6

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of IGFBP6 protein

NCBI chr 7:135,154,919...135,159,550
Ensembl chr 7:135,154,685...135,159,795

G

interleukin 10

increases expression

ISO

Asbestos, Amphibole results in increased expression of IL10 protein

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 17A

increases expression

ISO

Asbestos, Amphibole results in increased expression of IL17A protein

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331

G

interleukin 18

increases expression

ISO
EXP

Asbestos, Amphibole results in increased expression of IL18 protein
Asbestos, Amphibole results in increased expression of IL18 mRNA

PMID:20855422 PMID:27083413

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 1 alpha

increases expression

ISO

Asbestos, Amphibole results in increased expression of IL1A protein

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

increases expression
multiple interactions
increases secretion

ISO
EXP

Asbestos, Amphibole results in increased expression of IL1B protein
ferric chloride inhibits the reaction [Asbestos, Amphibole results in increased expression of IL1B mRNA]
Asbestos, Amphibole results in increased expression of IL1B mRNA; Asbestos, Amphibole results in increased expression of IL1B protein
[Asbestos, Amphibole results in increased secretion of IL1B protein] which results in increased phosphorylation of MAP3K8 protein; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Asbestos, Amphibole results in increased secretion of IL1B protein]
[Asbestos, Amphibole results in increased secretion of IL1B protein] which results in increased secretion of CSF2 protein; Asbestos, Amphibole results in increased secretion of IL1B protein

PMID:20855422 PMID:22168577 PMID:23017228 PMID:27083413

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 6

increases expression
multiple interactions

ISO
EXP

Asbestos, Amphibole results in increased expression of IL6 mRNA; Asbestos, Amphibole results in increased expression of IL6 protein
Deferoxamine inhibits the reaction [Asbestos, Amphibole results in increased expression of IL6 mRNA]

PMID:20855422 PMID:22168577 PMID:24401117 PMID:27083413 PMID:28870655

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

integrin subunit alpha 4

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of ITGA4 protein

NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039

G

kelch-like family member 4

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of KLHL4 mRNA

NCBI chr X:83,626,047...83,916,328
Ensembl chr X:83,819,076...83,916,328

G

kininogen 2

increases expression

EXP

Asbestos, Amphibole results in increased expression of KNG2 mRNA

NCBI chr11:91,418,470...91,440,841
Ensembl chr11:91,414,207...91,441,259

G

lymphotoxin alpha

increases expression

ISO

Asbestos, Amphibole results in increased expression of LTA protein

NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533

G

MAP3K7 C-terminal like

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of MAP3K7CL mRNA

NCBI chr11:40,276,839...40,321,848
Ensembl chr11:40,277,688...40,321,847

G

mitogen-activated protein kinase kinase kinase 8

increases phosphorylation
multiple interactions

ISO

Asbestos, Amphibole results in increased phosphorylation of MAP3K8 protein
[Asbestos, Amphibole results in increased secretion of IL1B protein] which results in increased phosphorylation of MAP3K8 protein

NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions

ISO
EXP

Asbestos, Amphibole results in increased phosphorylation of MAPK1 protein
ferric chloride inhibits the reaction [Asbestos, Amphibole results in increased phosphorylation of MAPK1 protein]

PMID:22168577 PMID:23017228

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 3

increases phosphorylation
multiple interactions

ISO
EXP

Asbestos, Amphibole results in increased phosphorylation of MAPK3 protein
ferric chloride inhibits the reaction [Asbestos, Amphibole results in increased phosphorylation of MAPK3 protein]

PMID:22168577 PMID:23017228

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

MDM2 proto-oncogene

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of MDM2 protein

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

macrophage migration inhibitory factor

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of MIF protein

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

mesothelin

increases expression

EXP

Asbestos, Amphibole results in increased expression of MSLN mRNA

NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153

G

metallothionein 2

increases expression

ISO

Asbestos, Amphibole results in increased expression of MT2A protein

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

nuclear factor kappa B subunit 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of NFKB1 protein

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

NFKB inhibitor alpha

increases expression

ISO

Asbestos, Amphibole results in increased expression of NFKBIA protein

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

NLR family, pyrin domain containing 3

decreases expression
increases expression

EXP

Asbestos, Amphibole results in decreased expression of NLRP3 mRNA
Asbestos, Amphibole results in increased expression of NLRP3 mRNA

PMID:22168577 PMID:27083413

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

nitric oxide synthase 2

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of NOS2 protein

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

neuronal regeneration related protein

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of NREP mRNA

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742

G

oxytocin receptor

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of OXTR mRNA

NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750

G

proliferating cell nuclear antigen

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of PCNA protein

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

platelet derived growth factor subunit A

decreases expression

EXP

Asbestos, Amphibole results in decreased expression of PDGFA mRNA

NCBI chr12:20,759,366...20,780,337
Ensembl chr12:20,754,208...20,780,322

G

pyruvate dehydrogenase kinase 4

increases expression

ISO

Asbestos, Amphibole results in increased expression of PDK4 mRNA

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381

G

pleckstrin homology-like domain, family A, member 1

increases expression

ISO

Asbestos, Amphibole results in increased expression of PHLDA1 mRNA

NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542

G

phospholipase C-like 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of PLCL1 mRNA

NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:64,361,520...64,733,171

G

cytochrome p450 oxidoreductase

affects expression

ISO

Asbestos, Amphibole affects the expression of POR protein

NCBI chr12:26,587,674...26,655,612
Ensembl chr12:26,587,674...26,635,809

G

periplakin

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of PPL mRNA

NCBI chr10:10,957,388...11,003,035
Ensembl chr10:10,957,341...11,003,658

G

peroxiredoxin 1

affects expression
increases expression

ISO

Asbestos, Amphibole affects the expression of PRDX1 protein
Asbestos, Amphibole results in increased expression of PRDX1 protein

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

peroxiredoxin 2

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of PRDX2 protein

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006

G

protein C receptor

increases expression

EXP

Asbestos, Amphibole results in increased expression of PROCR mRNA

NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:164,711,636...164,718,989

G

protein S

increases expression

EXP

Asbestos, Amphibole results in increased expression of PROS1 mRNA

NCBI chr11:13,676,310...13,757,858
Ensembl chr11:13,676,769...13,757,852

G

prostaglandin-endoperoxide synthase 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of PTGS1 protein

NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990

G

prostaglandin-endoperoxide synthase 2

increases expression

ISO
EXP

Asbestos, Amphibole results in increased expression of PTGS2 mRNA

PMID:20831825 PMID:20855422 PMID:22168577 PMID:24401117

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

RAD23 homolog A, nucleotide excision repair protein

increases expression

ISO

Asbestos, Amphibole results in increased expression of RAD23A protein

NCBI chr19:40,219,235...40,225,543
Ensembl chr19:40,219,636...40,225,543

G

RAD50 double strand break repair protein

affects expression

ISO

Asbestos, Amphibole affects the expression of RAD50 protein

NCBI chr10:38,310,147...38,362,100
Ensembl chr10:38,310,147...38,362,100

G

ribosomal protein S6

increases expression

EXP

Asbestos, Amphibole results in increased expression of RPS6 protein modified form

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566

G

serpin family E member 1

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of SERPINE1 protein

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

superoxide dismutase 1

increases expression
decreases expression

ISO

Asbestos, Amphibole results in increased expression of SOD1 protein
Asbestos, Amphibole results in decreased expression of SOD1 protein

PMID:20831825 PMID:20855422

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

increases expression

ISO

Asbestos, Amphibole results in increased expression of SOD2 mRNA; Asbestos, Amphibole results in increased expression of SOD2 protein

PMID:20831825 PMID:20855422

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

signal transducer and activator of transcription 3

increases expression

EXP

Asbestos, Amphibole results in increased expression of STAT3 protein modified form

NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359

G

tissue factor pathway inhibitor 2

increases expression

ISO
EXP

Asbestos, Amphibole results in increased expression of TFPI2 mRNA

PMID:20831825 PMID:22352330

NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426

G

transforming growth factor, beta 1

decreases expression

EXP

Asbestos, Amphibole results in decreased expression of TGFB1 mRNA

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

thrombomodulin

increases expression

EXP

Asbestos, Amphibole results in increased expression of THBD mRNA

NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582

G

thiol methyltransferase 1A

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of TMT1A mRNA

NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:133,330,447...133,338,959

G

tumor necrosis factor

increases expression

ISO
EXP

Asbestos, Amphibole results in increased expression of TNF mRNA; Asbestos, Amphibole results in increased expression of TNF protein

PMID:20855422 PMID:24401117 PMID:27083413 PMID:28870655

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 1A

affects expression

ISO

Asbestos, Amphibole affects the expression of TNFRSF1A protein

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF superfamily member 10

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of TNFSF10 protein

NCBI chr 2:112,136,550...112,155,903

G

tumor protein p53

multiple interactions
affects expression

ISO

Asbestos, Amphibole results in increased phosphorylation of and results in increased stability of TP53 protein
Asbestos, Amphibole affects the expression of TP53 protein

PMID:20705543 PMID:20855422

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

UDP glucuronosyltransferase family 1 member A5

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of UGT1A4 protein

NCBI chr 9:96,210,053...96,256,264
Ensembl chr 9:96,144,786...96,256,264

G

uracil-DNA glycosylase

decreases expression

ISO

Asbestos, Amphibole results in decreased expression of UNG protein

NCBI chr12:48,145,838...48,154,789
Ensembl chr12:48,145,838...48,155,257

G

WT1 transcription factor

increases expression

EXP

Asbestos, Amphibole results in increased expression of WT1 mRNA

NCBI chr 3:112,019,721...112,068,454
Ensembl chr 3:112,021,641...112,068,444

G

X-ray repair cross complementing 1

decreases response to substance
decreases expression

ISO

XRCC1 results in decreased susceptibility to Asbestos, Amphibole
Asbestos, Amphibole results in decreased expression of XRCC1 protein

PMID:20705543 PMID:20855422

NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613

G

X-ray repair cross complementing 2

increases expression

ISO

Asbestos, Amphibole results in increased expression of XRCC2 protein

NCBI chr 4:10,157,130...10,237,089
Ensembl chr 4:10,157,800...10,176,407

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adducin 1

affects expression

ISO

Asbestos affects the expression of ADD1 mRNA

NCBI chr14:80,333,242...80,401,641
Ensembl chr14:80,333,244...80,391,732

G

adhesion G protein-coupled receptor G6

affects expression

ISO

Asbestos affects the expression of ADGRG6 mRNA

NCBI chr 1:10,633,004...10,774,685
Ensembl chr 1:10,631,829...10,774,023

G

adrenoceptor beta 1

increases expression

ISO

Asbestos results in increased expression of ADRB1 mRNA

NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:265,766,079...265,849,237

G

adrenoceptor beta 2

decreases expression

ISO

Asbestos results in decreased expression of ADRB2 mRNA

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

angiotensin II receptor, type 1a

decreases expression

ISO

Asbestos results in decreased expression of AGTR1 mRNA

NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660

G

annexin A2

affects expression

ISO

Asbestos affects the expression of ANXA2 mRNA

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A3

decreases expression

ISO

Asbestos results in decreased expression of ANXA3 mRNA

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849

G

annexin A5

increases expression

ISO

Asbestos results in increased expression of ANXA5 mRNA

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

ankyrin repeat and SOCS box-containing 9

affects expression

ISO

Asbestos affects the expression of ASB9 mRNA

NCBI chr X:33,588,484...33,633,285
Ensembl chr X:33,588,484...33,624,397

G

activating transcription factor 3

increases expression

ISO

Asbestos results in increased expression of ATF3 mRNA

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

atlastin GTPase 2

affects expression

ISO

Asbestos affects the expression of ATL2 mRNA

NCBI chr 6:20,891,220...20,932,644
Ensembl chr 6:20,891,227...20,933,320

G

ATM serine/threonine kinase

affects expression
affects response to substance

ISO

Asbestos affects the expression of ATM mRNA
ATM alternative form affects the susceptibility to Asbestos

PMID:17297452 PMID:28687356

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

attractin

affects expression

ISO

Asbestos affects the expression of ATRN mRNA

NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360

G

beta-2 microglobulin

decreases expression

ISO

Asbestos results in decreased expression of B2M mRNA

NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356

G

BRCA1 associated deubiquitinase 1

increases mutagenesis
increases response to substance

ISO

Asbestos results in increased mutagenesis of BAP1 gene
BAP1 gene mutant form results in increased susceptibility to Asbestos

PMID:24928783 PMID:26463840

NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952

G

BCL2 associated X, apoptosis regulator

increases expression

ISO

Asbestos results in increased expression of BAX mRNA

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

Bcl-2 binding component 3

decreases expression

ISO

Asbestos results in decreased expression of BBC3

NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666

G

BCL2, apoptosis regulator

increases expression

ISO

Asbestos results in increased expression of BCL2 mRNA

PMID:22076105 PMID:22398240

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

Bcl2-like 11

decreases expression

ISO

Asbestos results in decreased expression of BCL2L11

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

BRCA1, DNA repair associated

affects response to substance

ISO

BRCA1 alternative form affects the susceptibility to Asbestos

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

BRCA2, DNA repair associated

affects response to substance

ISO

BRCA2 alternative form affects the susceptibility to Asbestos

NCBI chr12:4,895,092...4,939,340
Ensembl chr12:4,895,447...4,936,194

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

decreases expression

ISO

Asbestos results in decreased expression of CACNA2D1 mRNA

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

calcium voltage-gated channel auxiliary subunit alpha2delta 2

decreases expression

ISO

Asbestos results in decreased expression of CACNA2D2 mRNA

NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:116,950,907...117,081,759

G

calcium voltage-gated channel auxiliary subunit beta 4

increases expression

ISO

Asbestos results in increased expression of CACNB4 mRNA

NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:57,315,900...57,578,220

G

calbindin 2

decreases expression

ISO

Asbestos results in decreased expression of CALB2 mRNA

NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952

G

caspase 9

increases activity
multiple interactions

EXP

Asbestos results in increased activity of CASP9 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]; FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]

Ensembl chr 5:159,391,188...159,409,648

G

C-C motif chemokine ligand 11

increases expression

ISO

Asbestos results in increased expression of CCL11 protein

NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,525,862...67,530,575

G

C-C motif chemokine ligand 2

increases expression

ISO

Asbestos results in increased expression of CCL2 mRNA
Asbestos results in increased expression of CCL2 protein

PMID:18795166 PMID:22398240

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 3

increases expression

ISO

Asbestos results in increased expression of CCL3 protein

PMID:25162674 PMID:25940505

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 5

increases expression

ISO

Asbestos results in increased expression of CCL5 protein

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

cellular communication network factor 2

decreases expression

ISO

Asbestos results in decreased expression of CCN2 mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976

G

C-C motif chemokine receptor 2

affects expression

ISO

Asbestos affects the expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

C-C motif chemokine receptor 4

increases expression

ISO

Asbestos results in increased expression of CCR4 mRNA

NCBI chr 8:123,054,505...123,060,244
Ensembl chr 8:123,054,324...123,077,642

G

C-C motif chemokine receptor 7

increases expression

ISO

Asbestos results in increased expression of CCR7 mRNA

NCBI chr10:84,594,399...84,604,514
Ensembl chr10:84,593,594...84,604,501

G

CD34 molecule

decreases expression

ISO

Asbestos results in decreased expression of CD34 mRNA

NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315

G

Cd4 molecule

decreases expression

ISO

Asbestos results in decreased expression of CD4 mRNA

NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:159,356,337...159,381,461

G

CD40 molecule

increases expression

ISO

Asbestos results in increased expression of CD40 mRNA

NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847

G

Cd68 molecule

increases expression

ISO

Asbestos results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

CD86 molecule

affects expression

ISO

Asbestos affects the expression of CD86 mRNA

NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

Asbestos results in increased expression of CDKN1A protein

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 2A

decreases expression
increases mutagenesis
increases methylation

ISO

Asbestos results in decreased expression of CDKN2A mRNA
Asbestos results in increased mutagenesis of CDKN2A gene
Asbestos results in increased methylation of CDKN2A promoter

PMID:15911247 PMID:19375815 PMID:22076105

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

centrosomal protein 350

affects response to substance

ISO

CEP350 gene SNP affects the susceptibility to Asbestos

NCBI chr13:70,573,597...70,714,673
Ensembl chr13:70,573,597...70,714,673

G

carboxylesterase 1D

increases expression

ISO

Asbestos results in increased expression of CES1 mRNA

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

complement factor D

increases expression

ISO

[Asbestos results in increased expression of CFD protein] which results in increased expression of IL6 protein; Asbestos results in increased expression of CFD protein

NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572

G

C-type lectin domain containing 11A

increases expression

ISO

Asbestos results in increased expression of CLEC11A protein

NCBI chr 1:103,938,029...103,941,170
Ensembl chr 1:103,935,185...103,946,784

G

contactin 1

decreases expression

ISO

Asbestos results in decreased expression of CNTN1 mRNA

NCBI chr 7:125,142,638...125,440,397
Ensembl chr 7:125,142,696...125,440,391

G

collagen beta(1-O)galactosyltransferase 2

affects methylation

ISO

Asbestos affects the methylation of COLGALT2 gene

NCBI chr13:67,073,551...67,178,194
Ensembl chr13:67,073,551...67,178,194

G

colony stimulating factor 1

increases expression

ISO

Asbestos results in increased expression of CSF1 mRNA; Asbestos results in increased expression of CSF1 protein

PMID:22398240 PMID:25162674

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

colony stimulating factor 2

increases expression

ISO

Asbestos results in increased expression of CSF2 mRNA

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

colony stimulating factor 3

increases expression

ISO

Asbestos results in increased expression of CSF3 protein
Asbestos results in increased expression of CSF3 mRNA

PMID:18795166 PMID:22398240

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860

G

C-terminal binding protein 2

affects expression

ISO

Asbestos affects the expression of CTBP2 mRNA

NCBI chr 1:197,208,536...197,348,802
Ensembl chr 1:197,212,133...197,254,261

G

C-X-C motif chemokine ligand 1

increases expression

ISO

Asbestos results in increased expression of CXCL1 protein

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 12

increases expression

ISO

Asbestos results in increased expression of CXCL12 protein

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 2

increases expression

ISO

Asbestos results in increased expression of CXCL2 protein

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

increases expression

ISO

Asbestos results in increased expression of CXCL1 protein

PMID:18795166 PMID:25162674

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

CXXC finger protein 1

increases expression

ISO

Asbestos results in increased expression of CXXC1 mRNA

NCBI chr18:70,088,407...70,093,786
Ensembl chr18:70,088,460...70,093,778

G

cysteinyl leukotriene receptor 1

decreases expression

ISO

Asbestos results in decreased expression of CYSLTR1 mRNA

NCBI chr X:75,734,281...75,762,873
Ensembl chr X:75,734,270...75,763,050

G

endothelin converting enzyme 1

increases expression

ISO

Asbestos results in increased expression of ECE1 mRNA

NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719

G

endothelin 1

decreases expression

ISO

Asbestos results in decreased expression of EDN1 mRNA

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

ecto-NOX disulfide-thiol exchanger 2

affects response to substance

ISO

ENOX2 mRNA alternative form affects the susceptibility to Asbestos

NCBI chr X:133,148,813...133,470,914
Ensembl chr X:133,148,813...133,470,891

G

erythrocyte membrane protein band 4.1-like 3

decreases expression

ISO

Asbestos results in decreased expression of EPB41L3 mRNA

NCBI chr 9:116,502,864...116,707,274
Ensembl chr 9:116,462,807...116,707,274

G

epoxide hydrolase 1

affects response to substance

ISO

EPHX1 gene polymorphism affects the susceptibility to Asbestos; EPHX1 protein affects the susceptibility to Asbestos

PMID:15993904 PMID:17159790

NCBI chr13:95,246,079...95,275,852
Ensembl chr13:95,246,080...95,321,981

G

coagulation factor III, tissue factor

multiple interactions

ISO

Plicamycin inhibits the reaction [Asbestos results in increased expression of F3 mRNA]

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

FA complementation group C

affects response to substance

ISO

FANCC alternative form affects the susceptibility to Asbestos

NCBI chr17:1,686,374...1,818,672
Ensembl chr17:1,687,017...1,835,096

G

FA complementation group F

affects response to substance

ISO

FANCF alternative form affects the susceptibility to Asbestos

NCBI chr 1:110,585,054...110,587,870
Ensembl chr 1:110,576,389...110,587,863

G

FA complementation group I

affects response to substance

ISO

FANCI alternative form affects the susceptibility to Asbestos

NCBI chr 1:142,736,636...142,792,999
Ensembl chr 1:142,736,653...142,792,999

G

Fas cell surface death receptor

decreases expression
increases expression

ISO

Asbestos results in decreased expression of FAS mRNA
Asbestos results in increased expression of FAS mRNA

PMID:22076105 PMID:22398240

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

Fas ligand

decreases expression

ISO

Asbestos results in decreased expression of FASLG

NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503

G

F-box and leucine-rich repeat protein 12

affects expression

ISO

Asbestos affects the expression of FBXL12 mRNA

NCBI chr 8:27,453,042...27,459,136
Ensembl chr 8:27,445,823...27,457,772

G

fibroblast growth factor 10

multiple interactions
decreases expression

EXP
ISO

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]; FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]; U 0126 inhibits the reaction [FGF10 protein inhibits the reaction [Asbestos results in increased activity of CASP9 protein]]
Asbestos results in decreased expression of FGF10 mRNA

PMID:15618436 PMID:22076105

NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:52,533,939...52,610,980

G

fibrinogen-like 2

affects expression

ISO

Asbestos affects the expression of FGL2 mRNA

NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:14,602,771...14,608,405

G

FKBP prolyl isomerase 1A

affects expression

ISO

Asbestos affects the expression of FKBP1A mRNA

NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233

G

fibronectin 1

increases expression

ISO

Asbestos results in increased expression of FN1 mRNA

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

farnesyltransferase, CAAX box, subunit alpha

affects expression

ISO

Asbestos affects the expression of FNTA mRNA

NCBI chr16:72,767,864...72,786,193
Ensembl chr16:72,767,627...72,788,229

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Asbestos results in increased expression of FOS mRNA

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FosB proto-oncogene, AP-1 transcription factor subunit

decreases expression

ISO

Asbestos results in decreased expression of FOSB mRNA

NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477

G

FOS like 1, AP-1 transcription factor subunit

increases expression
multiple interactions

ISO

Asbestos results in increased expression of FOSL1 mRNA
tetramethylthiourea inhibits the reaction [Asbestos results in increased expression of FOSL1 mRNA]

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

forkhead box O1

decreases expression
multiple interactions

ISO

Asbestos results in decreased expression of FOXO1 mRNA
[Asbestos results in decreased expression of FOXO1 mRNA] which results in decreased susceptibility to Asbestos

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419

G

ferritin heavy chain 1

affects response to substance

ISO

FTH1 gene SNP affects the susceptibility to Asbestos

NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214

G

growth arrest and DNA-damage-inducible, alpha

decreases expression

ISO

Asbestos results in decreased expression of GADD45A mRNA

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

gamma-glutamyltransferase 1

decreases expression

ISO

Asbestos results in decreased expression of GGT1 mRNA

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050

G

GTPase, IMAP family member 6

affects expression

ISO

Asbestos affects the expression of GIMAP6 mRNA

NCBI chr 4:78,984,597...78,990,006
Ensembl chr 4:78,983,504...78,990,010

G

glutaredoxin

affects expression

ISO

Asbestos affects the expression of GLRX mRNA

NCBI chr 2:7,073,737...7,083,548
Ensembl chr 2:7,073,759...7,083,543

G

glycine-N-acyltransferase

decreases expression

ISO

Asbestos results in decreased expression of GLYAT mRNA

NCBI chr 1:219,128,798...219,149,615
Ensembl chr 1:219,128,811...219,150,774

G

G protein-coupled receptor 135

affects methylation

ISO

Asbestos affects the methylation of GPR135 gene

NCBI chr 6:96,363,466...96,366,594
Ensembl chr 6:96,362,867...96,382,988

G

glutathione S-transferase mu 1

increases response to substance
affects response to substance

ISO

GSTM1 gene polymorphism results in increased susceptibility to Asbestos
GSTM1 gene polymorphism affects the susceptibility to Asbestos

PMID:18420450 PMID:20847076

NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:198,338,008...198,343,569

G

glutathione S-transferase, mu 5

affects expression

ISO

Asbestos affects the expression of GSTM3 protein

NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:198,219,647...198,222,731

G

glutathione S-transferase pi 1

affects response to substance

ISO

GSTP1 gene polymorphism affects the susceptibility to Asbestos

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase theta 1

affects response to substance

ISO

GSTT1 gene polymorphism affects the susceptibility to Asbestos; GSTT1 protein affects the susceptibility to Asbestos

PMID:17563610 PMID:20847076

NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019

G

hephaestin

affects response to substance

ISO

HEPH gene SNP affects the susceptibility to Asbestos

NCBI chr X:65,160,628...65,412,457
Ensembl chr X:65,305,773...65,412,453

G

hepatocyte growth factor

increases expression

ISO

Asbestos results in increased expression of HGF protein

NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851

G

HMG-box containing 3

affects expression

ISO

Asbestos affects the expression of HMGXB3 mRNA

NCBI chr18:56,860,947...56,908,419
Ensembl chr18:56,860,947...56,908,419

G

heme oxygenase 1

increases expression

ISO

Asbestos results in increased expression of HMOX1 mRNA

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

histamine receptor H 1

increases expression

ISO

Asbestos results in increased expression of HRH1 mRNA

NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248

G

histamine receptor H 2

increases expression

ISO

Asbestos results in increased expression of HRH2 mRNA

NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,371,083...10,391,041

G

intercellular adhesion molecule 1

increases expression

ISO

Asbestos results in increased expression of ICAM1 mRNA

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

interferon gamma

increases expression

ISO

Asbestos results in increased expression of IFNG protein

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

intraflagellar transport 74

affects expression

ISO

Asbestos affects the expression of IFT74 mRNA

NCBI chr 5:114,576,106...114,679,581
Ensembl chr 5:114,593,397...114,679,581

G

insulin-like growth factor 2 mRNA binding protein 3

decreases expression

ISO

Asbestos results in decreased expression of IGF2BP3 mRNA

NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730

G

interleukin 10

increases expression

ISO

Asbestos results in increased expression of IL10 mRNA

PMID:22076105 PMID:22398240

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 17A

increases expression

ISO

Asbestos results in increased expression of IL17A protein

NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331

G

interleukin 1 alpha

decreases expression
increases expression

ISO

Asbestos results in decreased expression of IL1A mRNA
Asbestos results in increased expression of IL1A mRNA

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 2 receptor subunit alpha

increases expression

ISO

Asbestos results in increased expression of IL2RA protein

NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507

G

interleukin 4

increases expression

ISO

Asbestos results in increased expression of IL4 protein

PMID:18795166 PMID:25162674

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

interleukin 5

increases expression

ISO

Asbestos results in increased expression of IL5 protein
Asbestos results in increased expression of IL5 mRNA

PMID:18795166 PMID:22398240

NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003

G

interleukin 6

increases expression

ISO

[Asbestos results in increased expression of CFD protein] which results in increased expression of IL6 protein; Asbestos results in increased expression of IL6 mRNA
Asbestos results in increased expression of IL6 protein

PMID:18795166 PMID:22076105 PMID:22398240 PMID:22832039

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

integrin subunit alpha 4

affects expression

ISO

Asbestos affects the expression of ITGA4 mRNA

NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039

G

integrin subunit beta 2

decreases expression

ISO

Asbestos results in decreased expression of ITGB2 mRNA

NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

ISO

Asbestos results in increased expression of JUN mRNA

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

KRAS proto-oncogene, GTPase

increases mutagenesis

ISO

Asbestos results in increased mutagenesis of KRAS gene

NCBI chr 4:179,916,255...179,949,613
Ensembl chr 4:179,919,802...179,949,320

G

LIF receptor subunit alpha

affects expression

ISO

Asbestos affects the expression of LIFR mRNA

NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364

G

LDL receptor related protein associated protein 1

affects expression

ISO

Asbestos affects the expression of LRPAP1 mRNA

NCBI chr14:79,876,002...79,888,011
Ensembl chr14:79,875,708...79,890,034

G

lymphotoxin alpha

increases expression

ISO

Asbestos results in increased expression of LTA mRNA

NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,623,527...3,625,533

G

latent transforming growth factor beta binding protein 1

decreases expression

ISO

Asbestos results in decreased expression of LTBP1 mRNA

NCBI chr 6:25,781,625...26,177,346
Ensembl chr 6:25,781,638...26,454,036

G

leucine zipper like post translational regulator 1

affects expression

ISO

Asbestos affects the expression of LZTR1 mRNA

NCBI chr11:96,991,956...97,008,127
Ensembl chr11:96,991,590...97,007,851

G

macrophage erythroblast attacher, E3 ubiquitin ligase

affects expression

ISO

Asbestos affects the expression of MAEA mRNA

NCBI chr14:81,581,784...81,615,246
Ensembl chr14:81,581,785...81,615,202

G

MAF bZIP transcription factor B

affects expression

ISO

Asbestos affects the expression of MAFB mRNA

NCBI chr 3:169,417,890...169,419,810
Ensembl chr 3:169,416,945...169,419,975

G

mitogen activated protein kinase 1

decreases expression

ISO

Asbestos results in decreased expression of MAPK1 mRNA

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen activated protein kinase 14

increases activity

ISO

Asbestos results in increased activity of MAPK14 protein

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen-activated protein kinase 8

multiple interactions

ISO

Asbestos results in increased phosphorylation of and results in increased activity of MAPK8 protein

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

melanocortin 2 receptor

increases expression

ISO

Asbestos results in increased expression of MC2R mRNA

NCBI chr18:64,279,878...64,291,775
Ensembl chr18:64,277,360...64,291,881

G

mitochondrial elongation factor 1

affects expression

ISO

Asbestos affects the expression of MIEF1 mRNA

NCBI chr 7:113,666,918...113,679,550
Ensembl chr 7:113,666,901...113,683,977

G

macrophage migration inhibitory factor

increases expression

ISO

Asbestos results in increased expression of MIF protein

NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121

G

microRNA 1224

decreases expression

ISO

Asbestos results in decreased expression of MIR1224 mRNA

NCBI chr11:93,811,291...93,811,375

G

microRNA 148b

increases expression

ISO

Asbestos results in increased expression of MIR148B mRNA

NCBI chr 7:136,299,870...136,299,966
Ensembl chr 7:136,299,870...136,299,966

G

microRNA 202

decreases expression

ISO

Asbestos results in decreased expression of MIR202 mRNA

NCBI chr 1:204,184,345...204,184,416

G

microRNA 331

increases expression

ISO

Asbestos results in increased expression of MIR331 mRNA

NCBI chr 7:30,414,386...30,414,481

G

microRNA 671

decreases expression

ISO

Asbestos results in decreased expression of MIR671 mRNA

NCBI chr 4:11,473,194...11,473,274

G

microRNA 96

increases expression

ISO

Asbestos results in increased expression of MIR96 mRNA

NCBI chr 4:59,755,841...59,755,946

G

Mirlet7b host gene

affects response to substance

ISO

MIRLET7BHG gene SNP affects the susceptibility to Asbestos

G

microRNA let-7d

increases expression

ISO

Asbestos results in increased expression of MIRLET7D mRNA

NCBI chr17:16,322,260...16,322,357
Ensembl chr17:16,322,260...16,322,357

G

myeloperoxidase

increases response to substance

ISO

MPO gene polymorphism results in increased susceptibility to Asbestos

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

membrane spanning 4-domains A1

affects response to substance

ISO

MS4A1 mRNA affects the susceptibility to Asbestos

NCBI chr 1:217,331,274...217,351,934
Ensembl chr 1:217,331,274...217,343,447

G

membrane spanning 4-domains A6A

affects expression

ISO

Asbestos affects the expression of MS4A6A mRNA

NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013

G

mesothelin

increases expression

ISO

Asbestos results in increased expression of MSLN protein; Asbestos results in increased expression of MSLN protein modified form

PMID:19190155 PMID:27032653

NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153

G

MTSS I-BAR domain containing 1

decreases expression

ISO

Asbestos results in decreased expression of MTSS1 mRNA

NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303

G

muscle associated receptor tyrosine kinase

affects expression

ISO

Asbestos affects the expression of MUSK mRNA

NCBI chr 5:77,853,560...77,967,653
Ensembl chr 5:77,853,736...77,964,338

G

myosin VA

affects expression

ISO

Asbestos affects the expression of MYO5A mRNA

NCBI chr 8:84,692,524...84,860,564
Ensembl chr 8:84,692,910...84,856,265

G

myosin VIIA

affects expression

ISO

Asbestos affects the expression of MYO7A mRNA

NCBI chr 1:161,755,110...161,825,397
Ensembl chr 1:161,755,110...161,825,365

G

N-acetyltransferase 2

affects response to substance

ISO

NAT2 protein polymorphism affects the susceptibility to Asbestos

NCBI chr16:26,974,874...27,005,191
Ensembl chr16:26,974,601...26,976,304

G

neurocalcin delta

decreases expression

ISO

Asbestos results in decreased expression of NCALD mRNA

NCBI chr 7:70,417,683...70,849,763
Ensembl chr 7:70,419,433...70,849,482

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

increases response to substance

ISO

NF2 gene mutant form results in increased susceptibility to Asbestos

NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151

G

nuclear factor kappa B subunit 2

increases expression

ISO

Asbestos results in increased expression of NFKB2 mRNA

NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637

G

NLR family, pyrin domain containing 3

affects response to substance

ISO

NLRP3 gene SNP affects the susceptibility to Asbestos

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

nitric oxide synthase 2

increases expression

ISO

Asbestos results in increased expression of NOS2 protein

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

neuroplastin

affects methylation

ISO

Asbestos affects the methylation of NPTN gene

NCBI chr 8:67,892,678...67,959,231
Ensembl chr 8:67,892,702...67,959,236

G

neuregulin 2

affects methylation

ISO

Asbestos affects the methylation of NRG2 gene

NCBI chr18:27,890,578...28,072,538
Ensembl chr18:27,890,578...28,072,538

G

p21 (RAC1) activated kinase 3

decreases expression

ISO

Asbestos results in decreased expression of PAK3 mRNA

NCBI chr X:111,912,967...112,171,037
Ensembl chr X:111,913,059...112,165,035

G

partner and localizer of BRCA2

affects response to substance

ISO

PALB2 alternative form affects the susceptibility to Asbestos

NCBI chr 1:186,096,312...186,120,284
Ensembl chr 1:186,096,312...186,120,302

G

poly (ADP-ribose) polymerase 1

multiple interactions
increases expression

ISO

Asbestos results in increased expression of and results in decreased activity of PARP1 protein
Asbestos results in increased expression of PARP1 mRNA

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

POZ (BTB) and AT hook containing zinc finger 1

affects expression

ISO

Asbestos affects the expression of PATZ1 mRNA

NCBI chr14:82,378,226...82,396,679
Ensembl chr14:82,377,697...82,396,686

G

phospholipase C, beta 4

decreases expression

ISO

Asbestos results in decreased expression of PLCB4 mRNA

NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113

G

phospholipase C, delta 1

decreases expression

ISO

Asbestos results in decreased expression of PLCD1 mRNA

NCBI chr 8:127,672,955...127,695,939
Ensembl chr 8:127,672,980...127,695,939

G

phospholipase C, epsilon 1

decreases expression

ISO

Asbestos results in decreased expression of PLCE1 mRNA

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828

G

phospholipase C, gamma 1

decreases expression

ISO

Asbestos results in decreased expression of PLCG1 mRNA

NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050

G

PMS1 homolog 1, mismatch repair system component

affects response to substance

ISO

PMS1 alternative form affects the susceptibility to Asbestos

NCBI chr 9:55,721,393...55,832,225
Ensembl chr 9:55,745,374...55,832,221

G

peptidylprolyl isomerase G

affects expression

ISO

Asbestos affects the expression of PPIG mRNA

NCBI chr 3:74,891,846...74,923,010
Ensembl chr 3:74,891,846...74,920,750

G

peroxiredoxin 1

increases expression

ISO

Asbestos results in increased expression of PRDX1 protein

NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504

G

peroxiredoxin 2

increases expression

ISO

Asbestos results in increased expression of PRDX2 protein

NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006

G

prolyl endopeptidase-like

affects expression

ISO

Asbestos affects the expression of PREPL mRNA

NCBI chr 6:15,333,107...15,362,825
Ensembl chr 6:15,333,077...15,363,231

G

protein kinase cAMP-activated catalytic subunit alpha

affects expression

ISO

Asbestos affects the expression of PRKACA mRNA

NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494

G

PRKCSH beta subunit of glucosidase II

affects expression

ISO

Asbestos affects the expression of PRKCSH mRNA

NCBI chr 8:28,810,836...28,822,503
Ensembl chr 8:28,810,889...28,822,503

G

platelet-activating factor receptor

increases expression

ISO

Asbestos results in increased expression of PTAFR mRNA

NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:150,049,460...150,079,408

G

prostaglandin E receptor 2

decreases expression

ISO

Asbestos results in decreased expression of PTGER2 mRNA

NCBI chr15:20,694,765...20,708,475
Ensembl chr15:20,696,013...20,708,950

G

prostaglandin F receptor

increases expression

ISO

Asbestos results in increased expression of PTGFR mRNA

NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:243,393,350...243,425,623

G

prostaglandin I2 receptor

increases expression

ISO

Asbestos results in increased expression of PTGIR mRNA

NCBI chr 1:86,707,690...86,710,073
Ensembl chr 1:86,707,503...86,711,874

G

prostaglandin I2 synthase

decreases expression

ISO

Asbestos results in decreased expression of PTGIS mRNA

NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:176,335,437...176,407,650

G

prostaglandin-endoperoxide synthase 2

increases expression

ISO

Asbestos results in increased expression of PTGS2 mRNA

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

protein tyrosine kinase 2 beta

decreases expression

ISO

Asbestos results in decreased expression of PTK2B mRNA

NCBI chr15:44,536,275...44,656,754
Ensembl chr15:44,531,249...44,656,806

G

PYD and CARD domain containing

decreases response to substance

ISO

PYCARD gene mutant form results in decreased susceptibility to Asbestos

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

retinoic acid receptor, beta

affects methylation

ISO

Asbestos affects the methylation of RARB gene

NCBI chr15:10,837,252...11,482,037
Ensembl chr15:11,131,358...11,482,040

G

Ras association domain family member 1

increases methylation

ISO

Asbestos results in increased methylation of RASSF1 promoter

NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805

G

RELA proto-oncogene, NF-kB subunit

affects localization

EXP

Asbestos affects the localization of RELA protein

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

ribosomal protein L3-like

increases expression

ISO

Asbestos results in increased expression of RPL3L mRNA

NCBI chr10:14,258,446...14,268,989
Ensembl chr10:14,258,418...14,268,988

G

RT1 class II, locus Da

increases expression

ISO

Asbestos results in increased expression of HLA-DRA mRNA

NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383

G

RUNX family transcription factor 1

affects expression

ISO

Asbestos affects the expression of RUNX1 mRNA

NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925

G

selectin E

increases expression

ISO

Asbestos results in increased expression of SELE mRNA

NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903

G

serine incorporator 3

affects expression

ISO

Asbestos affects the expression of SERINC3 mRNA

NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:172,721,321...172,740,765

G

serpin family A member 1

increases response to substance

ISO

SERPINA1 gene polymorphism results in increased susceptibility to Asbestos

PMID:12368052 PMID:14748049

NCBI chr 6:128,631,101...128,653,125
Ensembl chr 6:128,619,382...128,660,703

G

sirtuin 6

affects expression

ISO

Asbestos affects the expression of SIRT6 mRNA

NCBI chr 7:8,733,056...8,738,543
Ensembl chr 7:8,732,974...8,738,542

G

solute carrier family 44, member 4

affects expression

ISO

Asbestos affects the expression of SLC44A4 mRNA

NCBI chr20:3,907,737...3,923,911
Ensembl chr20:3,907,737...3,923,854

G

solute carrier family 6 member 14

affects expression

ISO

Asbestos affects the expression of SLC6A14 mRNA

NCBI chr X:117,109,063...117,169,522
Ensembl chr X:117,108,947...117,169,828

G

SLX4 structure-specific endonuclease subunit

affects response to substance

ISO

SLX4 alternative form affects the susceptibility to Asbestos

NCBI chr10:12,032,131...12,055,685
Ensembl chr10:12,033,048...12,055,650

G

SMAD family member 2

multiple interactions

ISO

[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased expression of SMAD2 mRNA; [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased phosphorylation of SMAD2 protein

NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388

G

SMAD family member 3

multiple interactions

ISO

[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of and results in increased phosphorylation of SMAD3 protein; [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of SMAD3 mRNA

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324

G

superoxide dismutase 3

increases secretion
multiple interactions
affects response to substance

ISO

Asbestos results in increased secretion of SOD3 protein
SOD3 gene polymorphism promotes the reaction [Asbestos results in increased secretion of SOD3 protein]
SOD3 gene polymorphism affects the susceptibility to Asbestos; SOD3 protein affects the susceptibility to Asbestos

PMID:16458190 PMID:21362472

NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125

G

sorbin and SH3 domain containing 2

affects expression

ISO

Asbestos affects the expression of SORBS2 mRNA

NCBI chr16:53,167,795...53,481,300
Ensembl chr16:53,167,827...53,358,986

G

Sp1 transcription factor

increases expression

ISO

Asbestos results in increased expression of SP1

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

secreted phosphoprotein 1

increases expression

ISO

Asbestos results in increased expression of SPP1 protein

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

thromboxane A2 receptor

increases expression

ISO

Asbestos results in increased expression of TBXA2R mRNA

NCBI chr 7:9,034,077...9,041,489
Ensembl chr 7:9,034,108...9,038,905

G

thromboxane A synthase 1

increases expression

ISO

Asbestos results in increased expression of TBXAS1 mRNA

NCBI chr 4:68,631,841...68,803,959
Ensembl chr 4:68,631,838...68,803,969

G

transferrin

increases expression
affects response to substance

ISO

Asbestos results in increased expression of TF mRNA
TF gene SNP affects the susceptibility to Asbestos

PMID:22076105 PMID:26818092

NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:112,647,642...112,695,400

G

transferrin receptor

decreases expression
increases expression

ISO

Asbestos results in decreased expression of TFRC mRNA
Asbestos results in increased expression of TFRC mRNA

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta 1

increases expression
affects response to substance
decreases expression
multiple interactions

ISO
EXP

Asbestos results in increased expression of TGFB1 mRNA
TGFB1 gene SNP affects the susceptibility to Asbestos; TGFB1 protein polymorphism affects the susceptibility to Asbestos
Asbestos results in decreased expression of TGFB1 mRNA
TNF protein promotes the reaction [Asbestos results in increased expression of TGFB1]

PMID:11394717 PMID:19349911 PMID:22076105 PMID:22398240 PMID:24142982

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor, beta induced

decreases expression

ISO

Asbestos results in decreased expression of TGFBI mRNA

NCBI chr17:7,960,885...7,990,234
Ensembl chr17:7,960,516...7,990,471

G

transforming growth factor, beta receptor 2

multiple interactions

ISO

[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of TGFBR2 mRNA

NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469

G

TIMP metallopeptidase inhibitor 2

affects response to substance

ISO

TIMP2 gene SNP affects the susceptibility to Asbestos

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214

G

tumor necrosis factor

increases secretion
affects response to substance
increases expression
multiple interactions

ISO
EXP

Asbestos results in increased secretion of TNF protein
TNF polymorphism affects the susceptibility to Asbestos
Asbestos results in increased expression of TNF mRNA
TNF protein promotes the reaction [Asbestos results in increased expression of TGFB1]
Asbestos results in increased expression of TNF protein

PMID:11394717 PMID:18709470 PMID:18795166 PMID:20486865 PMID:22076105 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF receptor superfamily member 1A

increases expression

ISO

Asbestos results in increased expression of TNFRSF1A

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF receptor superfamily member 1B

decreases expression
increases expression

ISO

Asbestos results in decreased expression of TNFRSF1B mRNA
Asbestos results in increased expression of TNFRSF1B mRNA

NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:162,353,848...162,387,411

G

tumor protein p53

increases response to substance
increases expression
affects response to substance
affects localization

ISO

TRP53 gene mutant form results in increased susceptibility to Asbestos
Asbestos results in increased expression of TP53 protein
TP53 gene SNP affects the susceptibility to Asbestos
Asbestos affects the localization of TP53 protein

PMID:8049841 PMID:15136429 PMID:23435014 PMID:25466987

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p73

affects localization

ISO

Asbestos affects the localization of TP73 protein

NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552

G

tropomyosin 4

increases expression

ISO

Asbestos results in increased expression of TPM4 protein

NCBI chr16:17,718,442...17,732,483
Ensembl chr16:17,717,230...17,732,494

G

thyroid peroxidase

affects methylation

ISO

Asbestos affects the methylation of TPO gene

NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793

G

T cell receptor associated transmembrane adaptor 1

affects expression

ISO

Asbestos affects the expression of TRAT1 mRNA

NCBI chr11:65,498,742...65,540,823
Ensembl chr11:65,498,742...65,542,381

G

transient receptor potential cation channel, subfamily C, member 3

affects methylation

ISO

Asbestos affects the methylation of TRPC3 gene

NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:121,409,436...121,475,823

G

thioredoxin 1

increases expression

ISO

Asbestos results in increased expression of TXN protein

NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307

G

UV radiation resistance associated

affects expression

ISO

Asbestos affects the expression of UVRAG mRNA

NCBI chr 1:162,596,514...162,854,348
Ensembl chr 1:162,596,515...162,854,348

G

vascular endothelial growth factor A

increases expression

ISO

Asbestos results in increased expression of VEGFA mRNA

NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194

G

WAP four-disulfide core domain 2

affects expression

ISO

Asbestos affects the expression of WFDC2 mRNA

NCBI chr 3:173,706,091...173,735,055
Ensembl chr 3:173,706,460...173,712,161

G

XPC complex subunit, DNA damage recognition and repair factor

affects response to substance

ISO

XPC alternative form affects the susceptibility to Asbestos

NCBI chr 4:125,550,833...125,578,084
Ensembl chr 4:125,550,833...125,578,305

G

X-ray repair cross complementing 1

increases response to substance
affects response to substance

ISO

XRCC1 gene polymorphism results in increased susceptibility to Asbestos
XRCC1 protein affects the susceptibility to Asbestos

PMID:16564556 PMID:16944782

NCBI chr 1:89,268,721...89,296,619
Ensembl chr 1:89,268,644...89,296,613

G

X-ray repair cross complementing 3

increases response to substance

ISO

XRCC3 gene polymorphism results in increased susceptibility to Asbestos

NCBI chr 6:136,684,558...136,694,822
Ensembl chr 6:136,684,558...136,694,822

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

affects expression

ISO

Asbestos affects the expression of YWHAB mRNA

NCBI chr 3:173,078,904...173,101,508
Ensembl chr 3:173,079,041...173,101,854

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor nicotinic alpha 4 subunit

multiple interactions

ISO

Bentonite inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]]

NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:188,501,209...188,535,105

G

cholinergic receptor nicotinic beta 2 subunit

multiple interactions

ISO

Bentonite inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein co-treated with CHRNB2 protein]]

NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326

G

Fas cell surface death receptor

multiple interactions

EXP

Bentonite inhibits the reaction [deoxynivalenol results in increased expression of FAS protein]

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

glutamic--pyruvic transaminase

multiple interactions

EXP

Bentonite inhibits the reaction [deoxynivalenol results in increased expression of GPT protein]

NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160

G

tumor necrosis factor

multiple interactions
increases expression

EXP

Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF mRNA]; Bentonite inhibits the reaction [deoxynivalenol results in increased expression of TNF protein]
Bentonite results in increased expression of TNF protein

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

crocidolite asbestos

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 2510039O18 gene like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KIAA2013 mRNA

NCBI chr 5:163,655,082...163,661,346
Ensembl chr 5:163,655,106...163,661,660

G

alpha 1,4-galactosyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of A4GALT mRNA

NCBI chr 7:116,248,571...116,272,917
Ensembl chr 7:116,247,880...116,273,171

G

aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AASDHPPT mRNA

NCBI chr 8:9,731,592...9,748,934
Ensembl chr 8:9,738,172...9,748,953

G

apoptosis-associated tyrosine kinase

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of AATK promoter

NCBI chr10:105,789,171...105,825,634
Ensembl chr10:105,785,469...105,825,618

G

ATP binding cassette subfamily A member 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABCA8B mRNA

NCBI chr10:95,416,984...95,490,647
Ensembl chr10:95,416,205...95,490,452

G

ATP binding cassette subfamily B member 1A

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of ABCB1 protein
ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased expression of ABCB1 protein]

NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135

G

ATP-binding cassette, sub-family B member 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABCB1B mRNA

NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567

G

ATP binding cassette subfamily C member 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABCC10 mRNA

NCBI chr 9:22,154,811...22,174,743
Ensembl chr 9:22,154,804...22,174,743

G

ATP binding cassette subfamily D member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABCD2 mRNA

NCBI chr 7:124,142,597...124,191,202
Ensembl chr 7:124,142,595...124,191,202

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of ABHD2 mRNA
Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of ABHD2 mRNA]

PMID:18687144 PMID:19446018

NCBI chr 1:142,626,748...142,707,892
Ensembl chr 1:142,626,732...142,712,674

G

abl-interactor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABI2 mRNA

NCBI chr 9:69,321,072...69,490,630
Ensembl chr 9:69,321,150...69,490,597

G

ABI family member 3 binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABI3BP mRNA

NCBI chr11:57,381,282...57,597,989
Ensembl chr11:57,381,422...57,598,120

G

ABL proto-oncogene 2, non-receptor tyrosine kinase

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of ABL2 mRNA
Asbestos, Crocidolite affects the expression of ABL2 mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr13:71,223,902...71,319,770
Ensembl chr13:71,224,019...71,389,775

G

ABR activator of RhoGEF and GTPase

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ABR promoter

NCBI chr10:61,760,743...61,959,526
Ensembl chr10:61,760,743...61,959,467

G

ABRA C-terminal like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ABRACL mRNA

NCBI chr 1:14,474,802...14,484,992
Ensembl chr 1:14,474,803...14,485,055

G

acetyl-CoA acetyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACAT1 mRNA

NCBI chr 8:62,876,003...62,905,080
Ensembl chr 8:62,876,003...62,905,042

G

acyl-CoA binding domain containing 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACBD5 mRNA

NCBI chr17:90,114,250...90,156,286
Ensembl chr17:90,114,375...90,156,286

G

alkaline ceramidase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACER2 mRNA

NCBI chr 5:106,437,773...106,488,572
Ensembl chr 5:106,437,796...106,488,583

G

atypical chemokine receptor 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACKR3 mRNA

NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214

G

aconitase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACO2 protein

NCBI chr 7:115,265,816...115,308,931
Ensembl chr 7:115,265,791...115,308,892

G

acyl-CoA thioesterase 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACOT7 mRNA

NCBI chr 5:167,969,284...168,062,033
Ensembl chr 5:167,968,895...168,062,033

G

acyl-CoA thioesterase 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACOT8 mRNA

NCBI chr 3:173,950,530...173,962,188
Ensembl chr 3:173,950,531...173,962,570

G

acyl-CoA thioesterase 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACOT9 mRNA

NCBI chr X:43,922,943...43,973,311
Ensembl chr X:43,914,923...43,973,205

G

acyl-CoA oxidase 3, pristanoyl

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACOX3 mRNA

NCBI chr14:79,358,604...79,405,160
Ensembl chr14:79,302,042...79,400,881

G

acid phosphatase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACP3 mRNA

NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033

G

actin alpha 2, smooth muscle

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACTA2 mRNA; Asbestos, Crocidolite results in increased expression of ACTA2 protein

PMID:22573546 PMID:24160326 PMID:28056339

NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503

G

actin, beta

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACTB protein

NCBI chr12:16,776,664...16,779,634
Ensembl chr12:16,776,661...16,780,242

G

actinin, alpha 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACTN1 mRNA

NCBI chr 6:104,731,485...104,826,312
Ensembl chr 6:104,731,485...104,826,172

G

actinin alpha 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACTN3 mRNA

NCBI chr 1:211,588,473...211,604,401
Ensembl chr 1:211,588,474...211,604,401

G

actinin alpha 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACTN4 protein

NCBI chr 1:93,310,294...93,379,369
Ensembl chr 1:93,310,278...93,379,320

G

actin related protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACTR3 mRNA

NCBI chr13:39,353,413...39,396,509
Ensembl chr13:39,353,079...39,396,711

G

activin A receptor type 2A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ACVR2A mRNA

NCBI chr 3:53,614,143...53,701,933
Ensembl chr 3:53,614,171...53,701,941

G

acylphosphatase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ACYP1 mRNA

NCBI chr 6:110,650,213...110,663,404
Ensembl chr 6:110,650,213...110,663,612

G

ADAM metallopeptidase domain 22

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADAM22 mRNA

NCBI chr 4:26,670,984...26,925,843
Ensembl chr 4:26,671,112...26,925,843

G

ADAM metallopeptidase domain 33

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADAM33 mRNA

NCBI chr 3:138,715,428...138,736,392
Ensembl chr 3:138,724,046...138,736,347

G

ADAM metallopeptidase with thrombospondin type 1 motif, 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADAMTS5 mRNA

NCBI chr11:38,486,945...38,533,516
Ensembl chr11:38,486,955...38,533,516

G

ADAM metallopeptidase with thrombospondin type 1 motif, 9

affects expression

ISO

Asbestos, Crocidolite affects the expression of ADAMTS9 mRNA

NCBI chr 4:126,847,726...127,019,924
Ensembl chr 4:126,847,729...127,019,876

G

adenosine deaminase, RNA-specific

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADAR mRNA

NCBI chr 2:177,436,076...177,475,969
Ensembl chr 2:177,436,094...177,475,971

G

adenylate cyclase 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of ADCY3 mRNA

NCBI chr 6:32,819,602...32,923,174
Ensembl chr 6:32,843,961...32,923,173

G

adenylate cyclase 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADCY5 mRNA

NCBI chr11:78,976,861...79,123,343
Ensembl chr11:78,976,861...79,123,343

G

adhesion G protein-coupled receptor E5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADGRE5 mRNA

NCBI chr19:41,302,687...41,332,183
Ensembl chr19:41,303,213...41,324,641

G

adhesion G protein-coupled receptor L1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADGRL1 mRNA

NCBI chr19:41,107,162...41,148,752
Ensembl chr19:41,109,117...41,148,896

G

adhesion G protein-coupled receptor L3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADGRL3 mRNA

NCBI chr14:26,690,891...27,458,132
Ensembl chr14:26,722,194...27,280,418

G

adhesion G protein-coupled receptor L4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADGRL4 mRNA

NCBI chr 2:243,014,927...243,117,226
Ensembl chr 2:243,014,796...243,117,222

G

alcohol dehydrogenase 5 (class III), chi polypeptide

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADH5 mRNA

NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:229,648,501...229,665,232

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ADH7 mRNA

NCBI chr 2:229,422,125...229,436,584
Ensembl chr 2:229,421,252...229,436,691

G

adrenomedullin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADM mRNA

PMID:18687144 PMID:29279043

NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371

G

adrenomedullin 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of ADM2 mRNA

NCBI chr 7:122,272,808...122,274,594
Ensembl chr 7:122,272,808...122,274,594

G

adenosine A2B receptor

affects expression

ISO

Asbestos, Crocidolite affects the expression of ADORA2B mRNA

NCBI chr10:47,439,712...47,456,092
Ensembl chr10:47,439,701...47,456,091

G

ADP-ribosylserine hydrolase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADPRS mRNA

NCBI chr 5:143,898,542...143,903,816
Ensembl chr 5:143,898,542...143,903,816

G

adrenoceptor alpha 2A

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of ADRA2A mRNA
Asbestos, Crocidolite results in decreased expression of ADRA2A mRNA

PMID:17331233 PMID:19446018

NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:263,065,278...263,069,871

G

adrenoceptor beta 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADRB2 mRNA

PMID:18687144 PMID:25351596

NCBI chr18:57,912,760...57,914,802
Ensembl chr18:57,911,348...57,914,803

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ADRM1 mRNA

NCBI chr 3:187,643,043...187,647,805
Ensembl chr 3:187,642,654...187,648,483

G

AE binding protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AEBP2 mRNA

NCBI chr 4:175,258,286...175,297,149
Ensembl chr 4:175,258,887...175,326,422

G

ALF transcription elongation factor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AFF3 mRNA

NCBI chr 9:47,894,903...48,352,380
Ensembl chr 9:47,894,903...48,353,000

G

ALF transcription elongation factor 4

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of AFF4 mRNA
Asbestos, Crocidolite results in increased expression of AFF4 mRNA

PMID:18687144 PMID:29279043

NCBI chr10:37,998,319...38,080,580
Ensembl chr10:37,999,579...38,080,580

G

AFG2 AAA ATPase homolog B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AFG2B mRNA

NCBI chr 3:130,148,061...130,162,458
Ensembl chr 3:130,148,301...130,162,112

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AGAP3 mRNA

NCBI chr 4:11,567,191...11,617,610
Ensembl chr 4:11,567,191...11,617,285

G

AGBL carboxypeptidase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AGBL2 mRNA

NCBI chr 3:97,220,654...97,255,905
Ensembl chr 3:97,220,781...97,255,904

G

ArfGAP with FG repeats 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AGFG2 mRNA

NCBI chr12:24,649,008...24,692,069
Ensembl chr12:24,649,038...24,685,197

G

argonaute RISC catalytic component 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AGO2 mRNA

NCBI chr 7:106,907,209...106,994,124
Ensembl chr 7:106,918,125...106,993,980

G

1-acylglycerol-3-phosphate O-acyltransferase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AGPAT4 mRNA

NCBI chr 1:51,075,081...51,181,548
Ensembl chr 1:51,075,081...51,180,976

G

agrin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AGRN mRNA

NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539

G

AT hook containing transcription factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AHCTF1 mRNA

NCBI chr13:94,013,894...94,068,348
Ensembl chr13:94,014,469...94,068,058

G

adenosylhomocysteinase-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AHCYL2 mRNA

NCBI chr 4:59,348,747...59,498,503
Ensembl chr 4:59,348,217...59,498,502

G

aryl hydrocarbon receptor

decreases expression
increases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of AHR mRNA
Asbestos, Crocidolite results in increased expression of AHR mRNA
Asbestos, Crocidolite affects the expression of AHR mRNA

PMID:18687144 PMID:25757056 PMID:29523930

NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901

G

activator of Hsp90 ATPase activity 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AHSA1 mRNA

NCBI chr 6:112,644,287...112,652,290
Ensembl chr 6:112,644,479...112,655,595

G

activator of HSP90 ATPase homolog 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AHSA2 mRNA

NCBI chr14:101,677,447...101,688,706
Ensembl chr14:101,677,447...101,686,923

G

apoptosis inducing factor, mitochondria associated 1

affects localization

ISO

Asbestos, Crocidolite affects the localization of AIFM1 protein

NCBI chr X:132,528,107...132,567,237
Ensembl chr X:132,528,107...132,567,237

G

autoimmune regulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AIRE mRNA

NCBI chr20:10,635,775...10,650,709
Ensembl chr20:10,635,775...10,650,709

G

adenylate kinase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AK3 mRNA

NCBI chr 1:236,151,012...236,178,689
Ensembl chr 1:236,151,012...236,178,183

G

A-kinase anchoring protein 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKAP11 mRNA

NCBI chr15:60,320,839...60,365,480
Ensembl chr15:60,320,839...60,365,335

G

A-kinase anchoring protein 13

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKAP13 mRNA

NCBI chr 1:138,722,445...139,029,401
Ensembl chr 1:138,724,150...139,029,401

G

A-kinase anchoring protein 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKAP5 mRNA

NCBI chr 6:100,787,169...100,796,712
Ensembl chr 6:100,790,148...100,796,620

G

A-kinase anchoring protein 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKAP8 mRNA

NCBI chr 7:11,966,769...11,983,056
Ensembl chr 7:11,966,772...11,982,900

G

A-kinase anchoring protein 8 like

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKAP8L mRNA
Asbestos, Crocidolite results in increased expression of AKAP8L mRNA

PMID:19446018 PMID:29279043

NCBI chr 7:11,983,215...12,012,843
Ensembl chr 7:11,982,721...12,012,811

G

aldo-keto reductase family 1 member B1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AKR1B1 mRNA

NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:63,899,222...63,913,315

G

aldo-keto reductase family 1, member C2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AKR1C2 mRNA

NCBI chr17:70,669,684...70,717,935
Ensembl chr17:70,669,710...70,685,686

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions
increases expression
increases activity

ISO
EXP

Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein
Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of AKT1 protein; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased activity of AKT1 protein]; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased expression of AKT1 mRNA]
arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein]

PMID:14627993 PMID:15897870 PMID:17191120 PMID:17322126

NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610

G

AKT1 substrate 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AKT1S1 mRNA

NCBI chr 1:104,469,823...104,476,168
Ensembl chr 1:104,469,803...104,476,167

G

5'-aminolevulinate synthase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ALAS2 mRNA

NCBI chr X:22,890,650...22,914,046
Ensembl chr X:22,890,689...22,914,043

G

albumin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ALB mRNA

NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865

G

aldolase, fructose-bisphosphate A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ALDOA protein

NCBI chr 1:190,832,820...190,838,021
Ensembl chr 1:190,832,820...190,838,211

G

ALG11, alpha-1,2-mannosyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ALG11 mRNA

NCBI chr16:76,642,979...76,654,052
Ensembl chr16:76,646,795...76,654,040

G

alkB homolog 8, tRNA methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ALKBH8 mRNA

NCBI chr 6:6,121,402...6,198,226
Ensembl chr 6:6,124,253...6,198,080

G

alkaline phosphatase, placental

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ALPP mRNA

NCBI chr 9:95,213,763...95,216,509
Ensembl chr 9:95,213,374...95,219,451

G

alsin Rho guanine nucleotide exchange factor ALS2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ALS2 mRNA

NCBI chr 9:68,107,310...68,180,192
Ensembl chr 9:68,107,528...68,179,660

G

amelogenin, X-linked

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AMELX mRNA

NCBI chr X:28,648,803...28,660,099
Ensembl chr X:28,648,803...28,660,099

G

autocrine motility factor receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AMFR mRNA

NCBI chr19:11,002,451...11,038,182
Ensembl chr19:11,002,101...11,038,364

G

adhesion molecule with Ig like domain 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of AMIGO2 mRNA

PMID:24160326 PMID:25757056

NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218

G

angiomotin like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AMOTL2 mRNA

NCBI chr 8:112,182,060...112,198,032
Ensembl chr 8:112,181,863...112,198,030

G

amylase 2a5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of AMY2B mRNA

NCBI chr 2:203,949,578...203,958,111

G

anaphase-promoting complex subunit 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANAPC5 mRNA

NCBI chr12:39,409,519...39,442,518
Ensembl chr12:39,385,399...39,442,762

G

angel homolog 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANGEL2 mRNA

NCBI chr13:105,041,727...105,060,640
Ensembl chr13:105,041,728...105,060,640

G

angiopoietin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANGPT1 mRNA

NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696

G

angiopoietin 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANGPT4 mRNA

NCBI chr 3:160,880,539...160,913,923
Ensembl chr 3:160,880,728...160,913,921

G

ankyrin repeat and EF-hand domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKEF1 mRNA

NCBI chr 3:144,300,500...144,335,759
Ensembl chr 3:144,300,529...144,335,753

G

ankyrin repeat and FYVE domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKFY1 mRNA

NCBI chr10:57,810,781...57,882,495
Ensembl chr10:57,810,781...57,882,495

G

ankyrin repeat and IBR domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKIB1 mRNA

NCBI chr 4:31,288,393...31,412,500
Ensembl chr 4:31,288,142...31,412,504

G

ankyrin repeat domain 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ANKRD10 mRNA

NCBI chr16:84,566,021...84,591,849
Ensembl chr16:84,568,506...84,591,846

G

ankyrin repeat domain containing 11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ANKRD11 promoter

NCBI chr19:67,848,836...68,007,491
Ensembl chr19:67,848,844...68,007,491

G

ankyrin repeat domain 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ANKRD12 mRNA

NCBI chr 9:113,030,127...113,134,816
Ensembl chr 9:113,030,919...113,134,762

G

ankyrin repeat domain 13C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKRD13C mRNA

NCBI chr 2:249,679,752...249,729,272
Ensembl chr 2:249,681,872...249,729,272

G

ankyrin repeat domain 16

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKRD16 mRNA

NCBI chr17:71,645,171...71,658,377
Ensembl chr17:71,647,107...71,658,377

G

ankyrin repeat domain 46

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANKRD46 mRNA

NCBI chr 7:69,532,303...69,553,311
Ensembl chr 7:69,532,304...69,545,421

G

ankyrin repeat domain 52

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ANKRD52 promoter

NCBI chr 7:1,390,730...1,410,139
Ensembl chr 7:1,391,325...1,407,410

G

ankyrin repeat and sterile alpha motif domain containing 1B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ANKS1B mRNA

NCBI chr 7:26,200,649...27,366,552
Ensembl chr 7:26,201,240...27,364,943

G

anoctamin 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ANO1 promoter

NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:209,180,755...209,329,550

G

acidic nuclear phosphoprotein 32 family member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANP32A mRNA

NCBI chr 8:71,724,578...71,760,922
Ensembl chr 8:71,724,531...71,760,922

G

alanyl aminopeptidase, membrane

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ANPEP mRNA
Asbestos, Crocidolite results in decreased expression of ANPEP mRNA

PMID:19446018 PMID:24160326 PMID:29279043

NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101

G

ANTXR cell adhesion molecule 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANTXR1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892

G

annexin A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANXA1 mRNA

NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831

G

annexin A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ANXA2 protein

NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:78,986,242...79,022,631

G

annexin A3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANXA3 mRNA

NCBI chr14:13,031,675...13,085,678
Ensembl chr14:13,023,762...13,085,849

G

annexin A5

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANXA5 mRNA
Asbestos, Crocidolite results in increased expression of ANXA5 protein

PMID:29279043 PMID:29553831

NCBI chr 2:121,242,133...121,272,935
Ensembl chr 2:121,242,136...121,281,400

G

annexin A7

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of ANXA7 mRNA
Asbestos, Crocidolite results in increased expression of ANXA7 protein

PMID:29279043 PMID:29553831

NCBI chr15:3,869,180...3,897,827
Ensembl chr15:3,870,974...3,898,891

G

adaptor related protein complex 1 subunit sigma 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AP1S2 mRNA

NCBI chr X:34,204,601...34,230,819
Ensembl chr X:34,204,603...34,228,529

G

adaptor related protein complex 3 subunit mu 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AP3M1 mRNA

NCBI chr15:3,285,591...3,314,139
Ensembl chr15:3,295,444...3,313,104

G

adaptor related protein complex 3 subunit sigma 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AP3S1 mRNA

NCBI chr18:41,649,321...41,718,221
Ensembl chr18:41,648,796...41,767,641

G

adaptor related protein complex 5 subunit mu 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of AP5M1 mRNA

PMID:29279043 PMID:29523930

NCBI chr15:24,835,122...24,864,854
Ensembl chr15:24,835,100...24,862,606

G

APC down-regulated 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of APCDD1 mRNA

NCBI chr18:58,655,696...58,686,359
Ensembl chr18:58,655,919...58,686,356

G

apurinic/apyrimidinic endodeoxyribonuclease 1

affects localization
decreases expression
multiple interactions

ISO

Asbestos, Crocidolite affects the localization of APEX1 protein
Asbestos, Crocidolite results in decreased expression of APEX1 mRNA
diphenyleneiodonium inhibits the reaction [Asbestos, Crocidolite affects the localization of APEX1 protein]

PMID:12023366 PMID:29279043

NCBI chr15:26,618,146...26,620,330
Ensembl chr15:26,618,224...26,620,329

G

apoptosis inhibitor 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of API5 mRNA

NCBI chr 3:100,833,417...100,858,580
Ensembl chr 3:100,833,417...100,858,580

G

amyloid beta precursor like protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of APLP1 mRNA

NCBI chr 1:94,824,330...94,834,705
Ensembl chr 1:94,824,072...94,834,610

G

apolipoprotein O

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of APOO mRNA

NCBI chr X:63,151,736...63,256,696
Ensembl chr X:63,151,814...63,256,690

G

amyloid beta precursor protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of APP protein

NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of APPL1 mRNA

NCBI chr16:2,125,234...2,173,457
Ensembl chr16:2,125,234...2,173,421

G

amphiregulin

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of AREG mRNA
Asbestos, Crocidolite affects the expression of AREG mRNA

PMID:18687144 PMID:25757056

NCBI chr14:17,256,384...17,265,641
Ensembl chr14:17,256,384...17,265,641

G

ARF GTPase 3

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of ARF3 mRNA
Asbestos, Crocidolite affects the expression of ARF3 mRNA

PMID:19446018 PMID:29279043

NCBI chr 7:131,765,039...131,792,075
Ensembl chr 7:131,750,672...131,770,123

G

ARF GTPase activating protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARFGAP2 mRNA

NCBI chr 3:97,692,105...97,704,246
Ensembl chr 3:97,692,110...97,704,247

G

ARF GTPase activating protein 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of ARFGAP3 mRNA

NCBI chr 7:116,312,996...116,359,300
Ensembl chr 7:116,313,001...116,359,592

G

ARF related protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARFRP1 mRNA

NCBI chr 3:188,844,013...188,851,473
Ensembl chr 3:188,845,511...188,851,431

G

arginase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARG1 mRNA; Asbestos, Crocidolite results in increased expression of ARG1 protein

PMID:29279043 PMID:29507420

NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:22,295,322...22,307,713

G

arginase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARG2 mRNA

NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:103,668,988...103,694,375

G

Rho GTPase activating protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGAP1 mRNA

NCBI chr 3:98,077,064...98,099,163
Ensembl chr 3:98,077,150...98,099,154

G

Rho GTPase activating protein 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGAP10 mRNA

NCBI chr19:47,352,783...47,614,532
Ensembl chr19:47,352,276...47,614,531

G

Rho GTPase activating protein 12

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ARHGAP12 mRNA
Asbestos, Crocidolite results in decreased expression of ARHGAP12 mRNA

PMID:29279043 PMID:29523930

NCBI chr17:56,284,282...56,397,630
Ensembl chr17:56,284,286...56,397,563

G

Rho GTPase activating protein 23

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGAP23 mRNA

NCBI chr10:82,891,021...82,993,230
Ensembl chr10:82,890,853...82,993,228

G

Rho GTPase activating protein 26

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGAP26 mRNA

PMID:25351596 PMID:29279043

NCBI chr18:30,702,602...31,489,047
Ensembl chr18:31,089,787...31,489,047

G

Rho GTPase activating protein 42

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGAP42 mRNA

NCBI chr 8:14,436,478...14,666,588
Ensembl chr 8:14,419,256...14,666,385

G

Rho GTPase activating protein 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARHGAP9 mRNA

NCBI chr 7:65,034,023...65,042,336
Ensembl chr 7:65,034,144...65,042,336

G

Rho guanine nucleotide exchange factor 11

affects expression

ISO

Asbestos, Crocidolite affects the expression of ARHGEF11 mRNA

NCBI chr 2:175,372,269...175,493,852
Ensembl chr 2:175,372,290...175,493,852

G

Rho guanine nucleotide exchange factor 17

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ARHGEF17 promoter

NCBI chr 1:164,642,690...164,702,241
Ensembl chr 1:164,642,690...164,702,241

G

Rho/Rac guanine nucleotide exchange factor 18

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ARHGEF18 promoter

NCBI chr12:6,192,958...6,300,997
Ensembl chr12:6,128,661...6,300,997

G

Rho guanine nucleotide exchange factor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGEF3 mRNA

NCBI chr16:2,308,311...2,588,634
Ensembl chr16:2,308,400...2,588,819

G

Rho guanine nucleotide exchange factor 38

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARHGEF38 mRNA

NCBI chr 2:224,284,238...224,413,974
Ensembl chr 2:224,284,238...224,413,974

G

Rho guanine nucleotide exchange factor 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ARHGEF4 promoter

NCBI chr 9:44,357,716...44,500,959
Ensembl chr 9:44,357,736...44,501,550

G

AT-rich interaction domain 1A

affects expression

ISO

Asbestos, Crocidolite affects the expression of ARID1A mRNA

NCBI chr 5:151,192,014...151,269,291
Ensembl chr 5:151,192,014...151,265,386

G

AT-rich interaction domain 1B

affects expression

ISO

Asbestos, Crocidolite affects the expression of ARID1B mRNA

NCBI chr 1:47,973,199...48,328,793
Ensembl chr 1:47,973,997...48,328,793

G

AT-rich interaction domain 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARID2 mRNA

NCBI chr 7:129,326,371...129,443,813
Ensembl chr 7:129,324,137...129,443,187

G

AT-rich interaction domain 4A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARID4A mRNA

NCBI chr 6:95,258,429...95,335,987
Ensembl chr 6:95,258,429...95,329,840

G

AT-rich interaction domain 5B

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ARID5B mRNA
Asbestos, Crocidolite results in decreased expression of ARID5B mRNA

PMID:18687144 PMID:29279043

NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686

G

arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARK2C mRNA

NCBI chr18:73,259,736...73,375,987
Ensembl chr18:73,264,901...73,375,987

G

ARF like GTPase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL1 mRNA

NCBI chr 7:25,007,401...25,018,572
Ensembl chr 7:25,006,981...25,019,319

G

ARF like GTPase 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARL10 mRNA

NCBI chr17:10,035,320...10,043,732
Ensembl chr17:10,035,320...10,043,981

G

ARF like GTPase 15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL15 mRNA

NCBI chr 2:47,171,377...47,555,666
Ensembl chr 2:47,094,900...47,555,666

G

ARF like GTPase 16

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL16 mRNA

NCBI chr10:106,235,792...106,237,968
Ensembl chr10:106,235,792...106,237,968

G

ARF like GTPase 4A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL4A mRNA

NCBI chr 6:62,809,287...62,811,297
Ensembl chr 6:62,804,548...62,820,760

G

ARF like GTPase 4C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARL4C mRNA

NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:96,745,069...96,752,772

G

ARF like GTPase 5A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL5A mRNA

NCBI chr 3:57,287,599...57,312,488
Ensembl chr 3:57,289,846...57,312,488

G

ARF like GTPase 5B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARL5B mRNA

NCBI chr17:82,864,315...82,888,458
Ensembl chr17:82,864,287...82,890,646

G

ARL6 interacting reticulophagy regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:181,864,717...181,874,232
Ensembl chr 1:181,864,746...181,874,232

G

armadillo repeat containing 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARMC10 mRNA

NCBI chr 4:14,291,211...14,306,799
Ensembl chr 4:14,291,211...14,306,817

G

armadillo repeat containing 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARMC3 mRNA

NCBI chr17:86,722,436...86,825,899
Ensembl chr17:86,722,441...86,825,899

G

armadillo repeat containing, X-linked 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARMCX5 mRNA

NCBI chr X:103,501,552...103,505,978
Ensembl chr X:103,501,146...103,539,449

G

aryl hydrocarbon receptor nuclear translocator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARNT mRNA

NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:185,680,683...185,745,546

G

cAMP-regulated phosphoprotein 19

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ARPP19 mRNA

NCBI chr 8:84,660,166...84,683,012
Ensembl chr 8:119,691,942...119,692,385
Ensembl chr 8:119,691,942...119,692,385

G

arrestin domain containing 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARRDC3 mRNA

NCBI chr 2:12,873,202...12,885,716
Ensembl chr 2:12,873,202...12,885,875

G

ADP-ribosyltransferase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ART3 mRNA

NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,921,395...15,949,806

G

ARV1 homolog, fatty acid homeostasis modulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ARV1 mRNA

NCBI chr19:69,589,728...69,601,547
Ensembl chr19:69,589,328...69,601,537

G

N-acylsphingosine amidohydrolase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ASAH1 mRNA

NCBI chr16:57,669,927...57,701,349
Ensembl chr16:57,669,750...57,718,305

G

N-acylsphingosine amidohydrolase 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of ASAH2 mRNA

NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:239,278,994...239,382,024

G

ankyrin repeat and SOCS box-containing 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ASB7 mRNA

NCBI chr 1:129,621,462...129,677,788
Ensembl chr 1:129,635,330...129,677,505

G

activating signal cointegrator 1 complex subunit 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ASCC1 mRNA
Asbestos, Crocidolite results in decreased expression of ASCC1 mRNA

PMID:29279043 PMID:29523930

NCBI chr20:28,484,044...28,574,195
Ensembl chr20:28,483,956...28,574,200

G

anti-silencing function 1A histone chaperone

affects expression

ISO

Asbestos, Crocidolite affects the expression of ASF1A mRNA

NCBI chr20:33,436,632...33,451,478
Ensembl chr20:33,436,707...33,449,639

G

argininosuccinate lyase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ASL mRNA

NCBI chr12:32,295,779...32,313,257
Ensembl chr12:32,295,633...32,317,261

G

aspartate beta-hydroxylase domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ASPHD1 mRNA

NCBI chr 1:190,983,506...190,987,440
Ensembl chr 1:190,983,506...190,987,440

G

asporin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ASPN mRNA

NCBI chr17:15,286,338...15,310,567
Ensembl chr17:15,287,065...15,310,632

G

ASPSCR1 tether for SLC2A4, UBX domain containing

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ASPSCR1 mRNA

NCBI chr10:106,450,600...106,488,231
Ensembl chr10:106,450,567...106,488,579

G

asparaginase and isoaspartyl peptidase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ASRGL1 mRNA

NCBI chr 1:215,436,180...215,456,188
Ensembl chr 1:215,435,218...215,456,198

G

ATPase family, AAA domain containing 3A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATAD3A mRNA

NCBI chr 5:171,632,545...171,652,725
Ensembl chr 5:171,632,547...171,652,725

G

alpha tubulin acetyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATAT1 mRNA

NCBI chr20:2,849,399...2,862,614
Ensembl chr20:2,849,421...2,862,389

G

activating transcription factor 2

decreases phosphorylation
decreases expression

ISO

Asbestos, Crocidolite results in decreased phosphorylation of ATF2 protein
Asbestos, Crocidolite results in decreased expression of ATF2 mRNA

PMID:17191120 PMID:29279043

NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745

G

activating transcription factor 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATF3 mRNA

PMID:18687144 PMID:20831825 PMID:25757056

NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750

G

activating transcription factor 4

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of ATF4 mRNA
Asbestos, Crocidolite results in increased expression of ATF4 mRNA

PMID:17331233 PMID:25757056

NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739

G

activating transcription factor 6

affects expression

ISO

Asbestos, Crocidolite affects the expression of ATF6 mRNA

NCBI chr13:85,460,312...85,639,959
Ensembl chr13:85,462,840...85,640,033

G

activating transcription factor 7 interacting protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of ATF7IP mRNA

NCBI chr 4:171,117,122...171,202,871
Ensembl chr 4:171,117,122...171,202,867

G

autophagy related 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATG3 mRNA

NCBI chr11:69,130,948...69,159,280
Ensembl chr11:69,121,952...69,159,280

G

atlastin GTPase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATL3 mRNA

NCBI chr 1:214,110,127...214,151,098
Ensembl chr 1:214,109,702...214,152,510

G

ATM serine/threonine kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATM mRNA

NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629

G

atos homolog A

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ATOSA mRNA
Asbestos, Crocidolite results in decreased expression of ATOSA mRNA

PMID:18687144 PMID:29279043

NCBI chr 8:84,575,360...84,653,103
Ensembl chr 8:84,575,370...84,653,091

G

ATPase phospholipid transporting 11A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP11A mRNA

NCBI chr16:83,359,884...83,469,807
Ensembl chr16:83,359,884...83,469,767

G

ATPase phospholipid transporting 11B (putative)

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP11B mRNA

NCBI chr 2:120,513,535...120,619,249
Ensembl chr 2:120,513,552...120,619,249

G

ATPase phospholipid transporting 11C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP11C mRNA

NCBI chr X:143,600,763...143,788,407
Ensembl chr X:143,600,767...143,788,432

G

ATPase H+/K+ transporting non-gastric alpha2 subunit

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATP12A mRNA

NCBI chr15:34,559,209...34,583,866
Ensembl chr15:34,559,209...34,583,866

G

ATPase 13A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP13A1 mRNA

NCBI chr16:19,649,065...19,665,126
Ensembl chr16:19,649,066...19,665,120

G

ATPase Na+/K+ transporting subunit beta 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP1B1 mRNA

NCBI chr13:79,319,708...79,340,226
Ensembl chr13:79,319,706...79,340,549

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP2A2 mRNA

NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934

G

ATPase plasma membrane Ca2+ transporting 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP2B1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:35,622,461...35,731,904

G

ATP synthase membrane subunit c locus 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP5MC2 mRNA

NCBI chr 7:135,669,847...135,680,839
Ensembl chr 7:135,669,848...135,678,231

G

ATP synthase membrane subunit j

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP5MJ mRNA

NCBI chr 6:136,839,890...136,845,640
Ensembl chr 1:177,906,475...177,907,045
Ensembl chr 1:177,906,475...177,907,045

G

ATP synthase peripheral stalk-membrane subunit b

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP5PB mRNA

NCBI chr 2:196,112,459...196,123,737
Ensembl chr 2:196,112,108...196,124,387

G

ATP synthase peripheral stalk subunit F6

affects expression

ISO

Asbestos, Crocidolite affects the expression of ATP5PF mRNA

NCBI chr11:37,368,045...37,375,721
Ensembl chr11:37,368,042...37,375,466

G

ATPase H+ transporting V0 subunit B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATP6V0B mRNA

NCBI chr 5:136,708,823...136,710,339
Ensembl chr 5:136,708,823...136,716,828

G

ATPase, H+ transporting V0 subunit e2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP6V0E2 mRNA

NCBI chr 4:78,815,771...78,818,919
Ensembl chr 4:78,813,129...78,819,680

G

ATPase phospholipid transporting 8A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATP8A1 mRNA

NCBI chr14:40,668,932...40,911,465
Ensembl chr14:40,731,846...40,911,463

G

ATPase phospholipid transporting 8B1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ATP8B1 mRNA

NCBI chr18:60,286,605...60,427,862
Ensembl chr18:60,288,464...60,427,027

G

all-trans retinoic acid-induced differentiation factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATRAID mRNA

NCBI chr 6:31,035,194...31,039,779
Ensembl chr 6:31,035,194...31,040,946

G

attractin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATRN mRNA

NCBI chr 3:138,563,271...138,697,360
Ensembl chr 3:138,563,312...138,697,360

G

attractin like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATRNL1 mRNA

NCBI chr 1:266,676,051...267,216,847
Ensembl chr 1:266,675,852...267,216,842

G

ataxin 2-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ATXN2L mRNA

NCBI chr 1:190,508,878...190,526,263
Ensembl chr 1:190,508,878...190,520,579

G

aurora kinase C

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of AURKC promoter

NCBI chr 1:75,876,773...75,882,893
Ensembl chr 1:75,876,773...75,897,426

G

beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of B3GALNT1 mRNA

NCBI chr 2:156,157,234...156,187,037
Ensembl chr 2:156,156,265...156,188,404

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of B3GNT5 mRNA
Asbestos, Crocidolite affects the expression of B3GNT5 mRNA

PMID:18687144 PMID:25757056

NCBI chr11:94,645,480...94,657,584
Ensembl chr11:94,645,480...94,660,514

G

beta-1,4-galactosyltransferase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of B4GALT4 mRNA

NCBI chr11:75,501,358...75,527,291
Ensembl chr11:75,501,366...75,527,177

G

beta-1,4-glucuronyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of B4GAT1 mRNA

NCBI chr 1:211,772,644...211,774,866
Ensembl chr 1:211,772,606...211,775,442

G

BRISC and BRCA1 A complex member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BABAM2 mRNA

NCBI chr 6:30,089,065...30,467,508
Ensembl chr 6:30,071,611...30,467,341

G

BTB domain and CNC homolog 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BACH1 mRNA

PMID:18687144 PMID:19446018

NCBI chr11:40,425,721...40,461,118
Ensembl chr11:40,425,664...40,461,277

G

BAG cochaperone 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BAG3 mRNA

NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:192,475,828...192,557,280

G

Btg3 associated nuclear protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BANP mRNA

NCBI chr19:66,916,417...66,994,286
Ensembl chr19:66,916,267...66,991,317

G

BRCA1 associated deubiquitinase 1

increases response to substance

ISO

BAP1 gene mutant form results in increased susceptibility to Asbestos, Crocidolite

NCBI chr16:6,453,126...6,461,952
Ensembl chr16:6,452,974...6,461,952

G

BarH-like homeobox 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BARHL1 mRNA

NCBI chr 3:32,639,283...32,646,605
Ensembl chr 3:32,638,644...32,646,605

G

BARX homeobox 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of BARX1 promoter

NCBI chr17:16,196,764...16,200,239
Ensembl chr17:16,196,764...16,200,239

G

BCL2 associated X, apoptosis regulator

decreases expression
increases expression
affects expression

ISO
EXP

Asbestos, Crocidolite results in decreased expression of BAX protein
Asbestos, Crocidolite results in increased expression of BAX mRNA
Asbestos, Crocidolite affects the expression of BAX mRNA

PMID:12909582 PMID:17331233 PMID:21570478 PMID:29279043

NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429

G

basal body orientation factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BBOF1 mRNA

NCBI chr 6:109,786,363...109,812,153
Ensembl chr 6:109,786,363...109,812,147

G

Bardet-Biedl syndrome 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BBS7 mRNA

NCBI chr 2:121,362,884...121,402,473
Ensembl chr 2:121,362,885...121,402,473

G

brevican

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BCAN mRNA

NCBI chr 2:175,752,333...175,765,766
Ensembl chr 2:175,752,336...175,765,314

G

B-cell receptor-associated protein 31

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BCAP31 mRNA

NCBI chr X:156,548,911...156,581,002
Ensembl chr X:156,548,911...156,579,371

G

BCAR3 adaptor protein, NSP family member

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of BCAR3 mRNA
Asbestos, Crocidolite results in decreased expression of BCAR3 mRNA

PMID:18687144 PMID:29279043

NCBI chr 2:213,209,907...213,323,305
Ensembl chr 2:213,209,893...213,323,302

G

BCL10, immune signaling adaptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BCL10 mRNA

NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:237,501,134...237,511,829

G

BCL2, apoptosis regulator

increases expression
multiple interactions

EXP
ISO

Asbestos, Crocidolite results in increased expression of BCL2 mRNA
[Asbestos, Crocidolite results in decreased susceptibility to Asbestos, Crocidolite] which results in increased expression of BCL2 protein

PMID:12909582 PMID:22608188

NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900

G

BCL2-related protein A1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BCL2A1 mRNA

NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890

G

Bcl2-like 1

increases expression
decreases expression
affects expression

EXP
ISO

Asbestos, Crocidolite results in increased expression of BCL2L1 mRNA
Asbestos, Crocidolite results in decreased expression of BCL2L1 mRNA
Asbestos, Crocidolite affects the expression of BCL2L1 mRNA

PMID:12909582 PMID:17331233 PMID:29279043

NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907

G

Bcl2-like 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BCL2L11 mRNA

NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:135,817,562...135,960,695

G

Bcl2-like 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BCL2L2 mRNA

NCBI chr15:32,326,686...32,337,834
Ensembl chr15:32,326,020...32,335,379

G

BCL3, transcription coactivator

affects expression

ISO

Asbestos, Crocidolite affects the expression of BCL3 mRNA

NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:88,599,321...88,614,368

G

BCL6, transcription repressor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BCL6 mRNA

NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047

G

bradykinin receptor B1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BDKRB1 mRNA

NCBI chr 6:130,275,631...130,284,968
Ensembl chr 6:130,275,478...130,280,973

G

brain-derived neurotrophic factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BDNF mRNA

NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657

G

BEN domain containing 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BEND5 mRNA

NCBI chr 5:131,519,214...131,565,228
Ensembl chr 5:131,519,214...131,762,906

G

BEN domain containing 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BEND7 mRNA

NCBI chr17:78,392,489...78,475,459
Ensembl chr17:78,393,601...78,475,223

G

bestrophin 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of BEST1 promoter

NCBI chr 1:216,054,395...216,071,012
Ensembl chr 1:216,054,395...216,070,974

G

bestrophin 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of BEST4 promoter

NCBI chr 5:135,858,774...135,865,624
Ensembl chr 5:135,860,018...135,863,707

G

Bet1 golgi vesicular membrane trafficking protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BET1 mRNA

NCBI chr 4:33,070,892...33,081,162
Ensembl chr 4:33,070,891...33,081,164

G

brain expressed X-linked 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BEX2 mRNA

NCBI chr X:104,010,639...104,012,143
Ensembl chr X:104,010,371...104,011,236

G

brain expressed X-linked 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BEX3 mRNA

NCBI chr X:104,064,896...104,066,425
Ensembl chr X:104,064,515...104,075,906

G

biglycan

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of BGN mRNA
Asbestos, Crocidolite results in increased expression of BGN protein

PMID:29279043 PMID:29553831

NCBI chr X:156,348,633...156,360,797
Ensembl chr X:156,348,615...156,360,799

G

basic helix-loop-helix family, member e22

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of BHLHE22 mRNA
Asbestos, Crocidolite results in increased expression of BHLHE22 mRNA

PMID:19446018 PMID:29279043

NCBI chr 2:102,402,622...102,405,732
Ensembl chr 2:102,400,164...102,420,508

G

basic helix-loop-helix family, member e40

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BHLHE40 mRNA

PMID:18687144 PMID:25351596

NCBI chr 4:143,174,450...143,180,150
Ensembl chr 4:143,174,048...143,180,783

G

basic helix-loop-helix family, member e41

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BHLHE41 mRNA

NCBI chr 4:180,565,003...180,569,415
Ensembl chr 4:180,565,003...180,569,355

G

BICD cargo adaptor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BICD1 mRNA

NCBI chr 4:184,208,891...184,362,840
Ensembl chr 4:184,210,363...184,357,391

G

baculoviral IAP repeat-containing 3

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of BIRC3 mRNA
Asbestos, Crocidolite results in decreased expression of BIRC3 mRNA
Asbestos, Crocidolite affects the expression of BIRC3 mRNA

PMID:18687144 PMID:25351596 PMID:25757056 PMID:29523930

NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590

G

baculoviral IAP repeat-containing 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BIRC6 mRNA

NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:26,474,843...26,668,507

G

baculoviral IAP repeat-containing 7

affects expression

ISO

Asbestos, Crocidolite affects the expression of BIRC7 mRNA

NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:188,425,392...188,430,174

G

basophilic leukemia expressed protein BLES03

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C11ORF68 mRNA

NCBI chr 1:212,163,892...212,166,146
Ensembl chr 1:212,163,892...212,166,141

G

B-cell linker

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BLNK mRNA

NCBI chr 1:249,703,064...249,770,533
Ensembl chr 1:249,703,072...249,770,533

G

basic leucine zipper nuclear factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BLZF1 mRNA

NCBI chr13:79,174,898...79,190,116
Ensembl chr13:79,174,902...79,190,116

G

BMI1 proto-oncogene, polycomb ring finger

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BMI1 mRNA

NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024

G

bone morphogenetic protein 2

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of BMP2 mRNA
Asbestos, Crocidolite results in increased expression of BMP2 mRNA

PMID:25757056 PMID:28056339

NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:141,264,646...141,274,760

G

bone morphogenetic protein receptor type 1A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BMPR1A mRNA

NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,742,875...9,786,861

G

BCL2 interacting protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BNIP3 mRNA

NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962

G

BCL2 interacting protein 3 like

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of BNIP3L mRNA
Asbestos, Crocidolite results in decreased expression of BNIP3L mRNA

PMID:17331233 PMID:29279043

NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282

G

BOC cell adhesion associated, oncogene regulated

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BOC mRNA

NCBI chr11:69,628,703...69,704,009
Ensembl chr11:69,628,660...69,704,004

G

BLOC-1 related complex subunit 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BORCS8 mRNA

NCBI chr16:19,308,247...19,314,910
Ensembl chr16:19,308,247...19,314,963

G

BPI fold containing family A, member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BPIFA1 mRNA

NCBI chr 3:163,087,965...163,093,708
Ensembl chr 3:163,087,965...163,093,708

G

B-Raf proto-oncogene, serine/threonine kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BRAF mRNA

NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:69,342,813...69,476,931

G

BRCA1 associated protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BRAP mRNA

NCBI chr12:40,535,232...40,561,726
Ensembl chr12:40,535,232...40,561,726

G

BRCA1, DNA repair associated

affects expression

ISO

Asbestos, Crocidolite affects the expression of BRCA1 mRNA

NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763

G

BRO1 domain and CAAX motif containing

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BROX mRNA

NCBI chr13:97,451,736...97,471,598
Ensembl chr13:97,451,737...97,471,519

G

bromodomain and PHD finger containing, 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BRPF1 mRNA

NCBI chr 4:148,011,977...148,028,431
Ensembl chr 4:148,011,931...148,028,424

G

brain specific homeobox

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of BSX promoter

NCBI chr 8:50,151,204...50,154,960
Ensembl chr 8:50,151,204...50,154,960

G

BTB domain containing 17

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BTBD17 mRNA

NCBI chr10:100,325,177...100,331,669
Ensembl chr10:100,325,177...100,331,771

G

basic transcription factor 3-like 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BTF3L4 mRNA

NCBI chr 5:128,796,594...128,816,219
Ensembl chr 5:128,796,594...128,816,602

G

BTG anti-proliferation factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BTG1 mRNA

NCBI chr 7:33,228,149...33,230,406
Ensembl chr 7:33,227,833...33,230,406

G

BTG anti-proliferation factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BTG2 mRNA

NCBI chr13:48,083,931...48,087,690
Ensembl chr13:48,083,931...48,087,690

G

B and T lymphocyte associated

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BTLA mRNA

NCBI chr11:69,069,734...69,099,331
Ensembl chr11:69,052,644...69,093,224

G

butyrophilin, subfamily 2, member A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BTN2A2 mRNA

NCBI chr17:42,048,842...42,060,650
Ensembl chr17:42,048,842...42,060,650

G

BUB3 mitotic checkpoint protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of BUB3 mRNA

NCBI chr 1:195,760,532...195,771,140
Ensembl chr 1:195,758,105...195,791,028

G

BUD31 homolog

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BUD31 mRNA

NCBI chr12:14,576,602...14,584,132
Ensembl chr12:14,576,605...14,584,039

G

similar to human chromosome 3 open reading frame 52

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C3ORF52 mRNA

NCBI chr11:68,629,570...68,654,874
Ensembl chr11:68,629,570...68,654,868

G

similar to human chromosome 6 open reading frame 62

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of C6ORF62 mRNA

NCBI chr17:40,684,236...40,695,874
Ensembl chr17:40,684,236...40,704,043

G

C1GALT1-specific chaperone 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of C1GALT1C1 mRNA

NCBI chr X:122,243,736...122,248,217
Ensembl chr X:122,234,454...122,248,422

G

similar to human chromosome 19 open reading frame 33

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C19ORF33 mRNA

NCBI chr 1:93,677,305...93,678,141
Ensembl chr 1:93,677,305...93,678,141

G

complement C1r

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C1R protein

NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714

G

complement C1s

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of C1S protein
Asbestos, Crocidolite results in decreased expression of C1S1 mRNA

PMID:29279043 PMID:29553831

NCBI chr 4:159,116,549...159,128,736
Ensembl chr 4:159,116,549...159,128,736

G

similar to human chromosome 21 open reading frame 58

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of C21ORF58 mRNA

NCBI chr20:12,165,853...12,187,271
Ensembl chr20:12,174,928...12,186,503

G

similar to human chromosome 4 open reading frame 33

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of D3ERTD751E mRNA

NCBI chr 2:126,692,176...126,769,183
Ensembl chr 2:126,697,854...126,746,878

G

complement C3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C3 protein

NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339

G

similar to human chromosome 11 open reading frame 96

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C11ORF96 mRNA

NCBI chr 3:100,375,474...100,376,717
Ensembl chr 3:100,351,199...100,378,346

G

similar to human chromosome 15 open reading frame 48

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COXFA4L3 mRNA

NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:130,173,416...130,177,089

G

complement C4A (Rodgers blood group)

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C4A protein

NCBI chr20:4,010,306...4,024,707

G

complement C4B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C4B mRNA

NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,201,961...4,216,289

G

complement C5

decreases expression
increases expression
increases cleavage
multiple interactions

ISO

Asbestos, Crocidolite results in decreased expression of C5 mRNA
Asbestos, Crocidolite results in increased expression of C5 protein
Asbestos, Crocidolite results in increased cleavage of C5 protein
1,3-dimethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; [Egtazic Acid co-treated with Asbestos, Crocidolite] results in increased cleavage of C5 protein; [Ethylene Glycol co-treated with Asbestos, Crocidolite] results in increased cleavage of C5 protein; Ascorbic Acid inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Dithionite inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]

PMID:10777245 PMID:25351596 PMID:29553831

NCBI chr 3:38,668,174...38,759,468
Ensembl chr 3:38,668,174...38,759,468

G

complement C5a receptor 1

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of C5AR1 mRNA
Asbestos, Crocidolite results in decreased expression of C5AR1 mRNA

PMID:17331233 PMID:25351596

NCBI chr 1:86,077,309...86,088,001

G

complement C7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C7 protein

NCBI chr 2:55,815,687...55,892,605
Ensembl chr 2:55,816,807...55,892,672

G

similar to human chromosome 2 open reading frame 69

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of C2ORF69 mRNA

NCBI chr 9:66,444,084...66,452,720
Ensembl chr 9:66,444,112...66,453,983

G

similar to human chromosome 6 open reading frame 141

increases expression

ISO

Asbestos, Crocidolite results in increased expression of C6ORF141 mRNA

NCBI chr 9:27,521,466...27,525,644
Ensembl chr 9:27,521,466...27,525,644

G

carbonic anhydrase 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CA9 mRNA

NCBI chr 5:62,559,024...62,565,626
Ensembl chr 5:62,558,823...62,565,626

G

calcium binding protein 39-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAB39L mRNA

NCBI chr15:37,782,778...37,885,191
Ensembl chr15:37,782,870...37,919,742

G

ciliary associated calcium binding coiled-coil 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CABCOCO1 mRNA

NCBI chr20:20,057,462...20,166,732
Ensembl chr20:20,057,517...20,167,174

G

calcium voltage-gated channel auxiliary subunit alpha2delta 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CACNA2D1 mRNA

NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:19,905,764...20,330,147

G

calcium voltage-gated channel auxiliary subunit beta 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CACNB1 mRNA

NCBI chr10:83,494,509...83,515,164
Ensembl chr10:83,494,509...83,515,146

G

calcium voltage-gated channel auxiliary subunit beta 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CACNB4 mRNA

NCBI chr 3:57,315,900...57,578,271
Ensembl chr 3:57,315,900...57,578,220

G

calcyclin binding protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CACYBP mRNA

NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505

G

cell adhesion molecule 1

decreases expression
multiple interactions

ISO

Asbestos, Crocidolite results in decreased expression of CADM1 mRNA
SETD2 protein affects the reaction [Asbestos, Crocidolite results in decreased expression of CADM1 mRNA]

PMID:29279043 PMID:37147272

NCBI chr 8:56,744,374...57,075,264
Ensembl chr 8:56,744,372...57,080,192

G

calbindin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CALB2 protein

NCBI chr19:55,023,849...55,050,858
Ensembl chr19:55,023,838...55,057,952

G

calcitonin-related polypeptide alpha

decreases expression

EXP

Asbestos, Crocidolite results in decreased expression of CALCA mRNA

NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:178,312,638...178,317,529

G

calcium binding and coiled coil domain 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CALCOCO1 mRNA

NCBI chr 7:135,713,208...135,728,044
Ensembl chr 7:135,713,208...135,727,928

G

calneuron 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CALN1 mRNA

NCBI chr12:31,447,964...31,939,847

G

calreticulin 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CALR3 mRNA

NCBI chr16:17,430,105...17,456,777
Ensembl chr16:17,430,153...17,457,198

G

calcium/calmodulin-dependent protein kinase II delta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAMK2D mRNA

NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:217,698,551...217,960,276

G

calcium/calmodulin-dependent protein kinase II inhibitor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CAMK2N2 mRNA

NCBI chr11:93,792,112...93,796,153
Ensembl chr11:93,794,095...93,795,222

G

calcium/calmodulin-dependent protein kinase IV

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CAMK4 promoter

NCBI chr18:24,857,152...25,076,054
Ensembl chr18:24,857,146...25,077,193

G

calmodulin regulated spectrin-associated protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAMSAP1 mRNA

NCBI chr 3:29,144,318...29,206,382
Ensembl chr 3:29,144,318...29,204,184

G

calmodulin binding transcription activator 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAMTA2 mRNA

NCBI chr10:55,882,071...55,900,575
Ensembl chr10:55,882,071...55,900,179

G

cullin-associated and neddylation-dissociated 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAND1 mRNA

NCBI chr 7:56,566,765...56,604,653
Ensembl chr 7:56,551,394...56,604,655

G

calpain 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAPN2 mRNA

NCBI chr13:96,681,902...96,732,625
Ensembl chr13:96,681,848...96,732,625

G

calpain 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAPN7 mRNA

NCBI chr16:6,552,048...6,588,317
Ensembl chr16:6,552,049...6,588,316

G

calpain, small subunit 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CAPNS1 mRNA
Asbestos, Crocidolite results in decreased expression of CAPNS1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:94,572,083...94,582,332
Ensembl chr 1:94,572,083...94,583,368

G

capping actin protein of muscle Z-line subunit alpha 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAPZA2 mRNA

NCBI chr 4:46,944,040...46,979,930
Ensembl chr 4:46,895,701...46,979,938

G

calcium responsive transcription factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CARF mRNA

NCBI chr 9:68,996,419...69,046,480
Ensembl chr 9:68,996,250...69,046,479

G

capping protein regulator and myosin 1 linker 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of CARMIL1 mRNA

NCBI chr17:41,235,819...41,516,204
Ensembl chr17:41,236,229...41,516,221

G

caspase 1

increases secretion
increases expression
increases activity
increases cleavage
multiple interactions

ISO

Asbestos, Crocidolite results in increased secretion of CASP1 protein modified form
Asbestos, Crocidolite results in increased expression of CASP1 mRNA; Asbestos, Crocidolite results in increased expression of CASP1 protein modified form
Asbestos, Crocidolite results in increased activity of CASP1 protein
Asbestos, Crocidolite results in increased cleavage of CASP1 protein
[CASP1 protein affects the susceptibility to Asbestos, Crocidolite] which affects the expression of FGF2 protein; [CASP1 protein affects the susceptibility to Asbestos, Crocidolite] which affects the expression of TFPI2 protein; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; CASP1 protein affects the reaction [Asbestos, Crocidolite results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; Silicon Dioxide analog inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of CASP1 protein modified form]; CASP1 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; Y 27632 inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CASP1 protein modified form]

PMID:18403674 PMID:23937860 PMID:24760326 PMID:24885895 PMID:25351596 More...

NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275

G

caspase 2

increases expression

EXP

Asbestos, Crocidolite results in increased expression of CASP2 mRNA

NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:72,116,246...72,134,022

G

caspase 3

multiple interactions
increases activity
increases cleavage
increases expression

ISO
EXP

Asbestos, Crocidolite inhibits the reaction [Asbestos, Crocidolite results in increased activity of CASP3 protein]
Antigens, Polyomavirus Transforming promotes the reaction [Asbestos, Crocidolite results in increased activity of CASP3 protein]; OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of CASP3 protein modified form]
Asbestos, Crocidolite results in increased cleavage of CASP3 protein
Asbestos, Crocidolite results in increased expression of CASP3 mRNA

PMID:12909582 PMID:17191120 PMID:19783790 PMID:22608188 PMID:24130165 More...

NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732

G

caspase 7

increases activity

ISO

Asbestos, Crocidolite results in increased activity of CASP7 protein

NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512

G

caspase 8

multiple interactions
increases expression
increases activity

ISO

Asbestos, Crocidolite inhibits the reaction [Asbestos, Crocidolite results in increased activity of CASP8 protein]
Asbestos, Crocidolite results in increased expression of CASP8 mRNA; Asbestos, Crocidolite results in increased expression of CASP8 protein

PMID:22608188 PMID:23634900

NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699

G

caspase 9

multiple interactions
increases activity
increases cleavage
increases expression

ISO

rottlerin inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of CASP9 protein]
Asbestos, Crocidolite results in increased activity of CASP9 protein
Asbestos, Crocidolite inhibits the reaction [Asbestos, Crocidolite results in increased activity of CASP9 protein]
Asbestos, Crocidolite results in increased expression of CASP9 protein modified form

PMID:12626342 PMID:17191120 PMID:22608188 PMID:24918270

Ensembl chr 5:159,391,188...159,409,648

G

calpastatin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAST mRNA

NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:5,707,640...5,817,180

G

catalase

multiple interactions
increases activity

ISO
EXP

CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of EGFR protein]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
Asbestos, Crocidolite results in increased activity of CAT protein
CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK7 protein]

PMID:1316905 PMID:12361925 PMID:14737115 PMID:16908449

NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526

G

cation channel, sperm associated 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CATSPER1 mRNA

NCBI chr 1:212,072,371...212,081,179
Ensembl chr 1:212,072,412...212,081,178

G

cation channel, sperm associated 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CATSPER2 mRNA

NCBI chr 3:128,822,387...128,842,501
Ensembl chr 3:128,822,391...128,842,261

G

caveolin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAV1 mRNA

NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:46,600,738...46,639,740

G

caveolin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAV2 mRNA

NCBI chr 4:46,582,681...46,590,058
Ensembl chr 4:46,582,096...46,591,425

G

caveolae associated protein 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of CAVIN2 mRNA

NCBI chr 9:57,794,007...57,806,024
Ensembl chr 9:57,794,019...57,806,024

G

caveolae associated protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CAVIN3 mRNA

NCBI chr 1:169,238,384...169,239,973
Ensembl chr 1:169,238,384...169,239,981

G

Cbl proto-oncogene B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBLB mRNA

NCBI chr11:62,058,829...62,225,904
Ensembl chr11:62,061,653...62,225,778

G

Cbl proto-oncogene like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBLL1 mRNA

NCBI chr 6:53,798,712...53,812,890
Ensembl chr 6:53,798,712...53,813,880

G

chromobox 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBX1 mRNA

NCBI chr10:82,266,746...82,286,431
Ensembl chr10:82,266,759...82,287,242

G

chromobox 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBX3 mRNA

NCBI chr 4:81,876,155...81,889,912
Ensembl chr 4:81,876,649...81,889,911

G

chromobox 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBX5 mRNA

NCBI chr 7:136,203,827...136,254,575
Ensembl chr 7:136,211,649...136,229,118

G

chromobox 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CBX7 mRNA

NCBI chr 7:113,341,030...113,358,716
Ensembl chr 7:113,341,030...113,358,346

G

coiled-coil and C2 domain containing 2A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CC2D2A mRNA

NCBI chr14:71,563,835...71,648,352
Ensembl chr14:71,563,835...71,648,331

G

collagen and calcium binding EGF domains 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCBE1 mRNA

NCBI chr18:61,849,821...62,093,876
Ensembl chr18:61,853,149...62,094,075

G

coiled-coil domain containing 162

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC162P mRNA

NCBI chr20:46,627,277...46,820,216
Ensembl chr20:46,627,277...46,818,249

G

coiled-coil domain containing 167

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCDC167 mRNA

NCBI chr20:7,768,425...7,783,181
Ensembl chr20:7,753,072...7,783,181

G

coiled-coil domain containing 18

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC18 mRNA

NCBI chr14:1,646,725...1,752,581
Ensembl chr14:1,646,809...1,750,470

G

coiled-coil domain containing 182

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCDC182 mRNA

NCBI chr10:73,587,416...73,588,228
Ensembl chr10:73,584,982...73,610,145

G

coiled-coil domain containing 190

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC190 mRNA

NCBI chr13:84,679,959...84,687,661
Ensembl chr13:84,679,986...84,687,658

G

coiled-coil domain containing 47

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC47 mRNA

NCBI chr10:91,630,101...91,648,626
Ensembl chr10:91,630,106...91,648,626

G

coiled-coil domain containing 50

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CCDC50 mRNA
Asbestos, Crocidolite results in decreased expression of CCDC50 mRNA

PMID:18687144 PMID:29279043

NCBI chr11:86,837,624...86,900,164
Ensembl chr11:86,837,624...86,899,980

G

coiled-coil domain containing 59

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC59 mRNA

NCBI chr 7:43,029,272...43,035,655
Ensembl chr 7:43,029,272...43,035,655

G

coiled-coil domain containing 68

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CCDC68 mRNA
Asbestos, Crocidolite results in decreased expression of CCDC68 mRNA

PMID:18687144 PMID:29279043

NCBI chr18:65,817,232...65,859,529
Ensembl chr18:65,786,926...65,859,526

G

coiled-coil domain containing 71-like

affects expression

ISO

Asbestos, Crocidolite affects the expression of CCDC71L mRNA

NCBI chr 6:54,687,474...54,691,566
Ensembl chr 6:54,617,540...55,014,344

G

coiled-coil domain containing 77

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC77 mRNA

NCBI chr 4:155,206,402...155,238,235
Ensembl chr 4:155,193,275...155,239,207

G

coiled-coil domain containing 85A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC85A mRNA

NCBI chr14:106,327,580...106,560,205
Ensembl chr14:106,327,580...106,560,165

G

coiled-coil domain containing 85B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCDC85B mRNA

NCBI chr 1:212,192,979...212,193,994
Ensembl chr 1:212,189,468...212,196,911

G

coiled coil domain containing 88A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC88A mRNA

NCBI chr14:107,304,654...107,456,104
Ensembl chr14:107,305,199...107,453,285

G

coiled-coil domain containing 91

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCDC91 mRNA

NCBI chr 4:182,132,931...182,304,948
Ensembl chr 4:182,132,942...182,304,948

G

C-C motif chemokine ligand 17

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL17 protein

NCBI chr19:10,208,120...10,218,340
Ensembl chr19:10,208,120...10,209,895

G

C-C motif chemokine ligand 2

increases expression
decreases secretion
increases secretion
multiple interactions

ISO
EXP

Asbestos, Crocidolite results in increased expression of CCL2 mRNA
Asbestos, Crocidolite results in increased expression of CCL2 mRNA; Asbestos, Crocidolite results in increased expression of CCL2 protein
Asbestos, Crocidolite results in decreased secretion of CCL2 protein
Asbestos, Crocidolite results in increased secretion of CCL2 protein
IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CCL2 mRNA]; IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CCL2 protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CCL2 protein]

PMID:10923243 PMID:16601788 PMID:19041333 PMID:23634900 PMID:23917077 More...

NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875

G

C-C motif chemokine ligand 20

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL20 mRNA

PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736

G

C-C motif chemokine ligand 22

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL22 protein

NCBI chr19:10,263,589...10,270,359
Ensembl chr19:10,263,589...10,270,359

G

C-C motif chemokine ligand 24

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL24 mRNA

NCBI chr12:26,737,423...26,741,420
Ensembl chr12:26,737,439...26,750,924

G

C-C motif chemokine ligand 27

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL27A mRNA

NCBI chr 5:61,737,261...61,744,375
Ensembl chr 5:61,737,261...61,743,522

G

C-C motif chemokine ligand 3

increases expression

EXP
ISO

Asbestos, Crocidolite results in increased expression of CCL3 protein
Asbestos, Crocidolite results in increased expression of CCL3 mRNA; Asbestos, Crocidolite results in increased expression of CCL3 protein

PMID:16601788 PMID:29279043 PMID:29507420

NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439

G

C-C motif chemokine ligand 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL4 mRNA; Asbestos, Crocidolite results in increased expression of CCL4 protein

PMID:29279043 PMID:29507420

NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,950,289...68,965,722

G

C-C motif chemokine ligand 5

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCL5 mRNA
Asbestos, Crocidolite results in increased expression of CCL5 mRNA; Asbestos, Crocidolite results in increased expression of CCL5 protein

PMID:29507420 PMID:29523930

NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884

G

C-C motif chemokine ligand 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCL6 mRNA

PMID:23917077 PMID:29507420

NCBI chr10:68,863,994...68,868,928
Ensembl chr10:68,863,995...68,868,877

G

cellular communication network factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCN1 mRNA

PMID:18687144 PMID:25351596

NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883

G

cellular communication network factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCN2 mRNA

NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976

G

cyclin A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCNA2 mRNA

NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701

G

cyclin B1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCNB1 mRNA

NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225

G

cyclin D1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCND1 protein

PMID:15374964 PMID:21570478 PMID:38301883

NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810

G

cyclin D2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCND2 mRNA

NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301

G

cyclin E1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of CCNE1 mRNA
Asbestos, Crocidolite results in increased expression of CCNE1 protein

PMID:17331233 PMID:21570478

NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822

G

cyclin G1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCNG1 mRNA

NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766

G

cyclin L1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCNL1 mRNA

NCBI chr 2:152,495,169...152,508,855
Ensembl chr 2:152,495,172...152,507,468

G

cyclin L2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCNL2 mRNA

NCBI chr 5:171,698,951...171,711,037
Ensembl chr 5:171,699,689...171,711,231

G

cell cycle progression 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCPG1 mRNA

NCBI chr 8:82,600,677...82,633,082
Ensembl chr 8:82,600,536...82,660,246

G

C-C motif chemokine receptor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCR1 mRNA

NCBI chr 8:132,433,711...132,439,266
Ensembl chr 8:132,431,592...132,439,374

G

C-C motif chemokine receptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCR2 mRNA

NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:132,611,410...132,620,059

G

C-C motif chemokine receptor 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCR3 mRNA

NCBI chr 8:132,463,533...132,511,601
Ensembl chr 8:132,463,788...132,511,593

G

C-C motif chemokine receptor 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CCR5 mRNA

PMID:29279043 PMID:29507420

NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:132,629,683...132,637,594

G

copper chaperone for superoxide dismutase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCS mRNA

NCBI chr 1:211,543,192...211,564,354
Ensembl chr 1:211,542,701...211,564,260

G

chaperonin containing TCP1 subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CCT4 mRNA

NCBI chr14:101,193,057...101,205,935
Ensembl chr14:101,192,772...101,205,770

G

CD14 molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CD14 mRNA

NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292

G

CD163 molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CD163 mRNA

PMID:29507420 PMID:38605572

NCBI chr 4:158,770,751...158,804,146
Ensembl chr 4:158,770,749...158,804,146

G

Cd200 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD200 mRNA

NCBI chr11:68,916,200...68,943,570
Ensembl chr11:68,916,224...68,943,569

G

CD22 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD22 mRNA

NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:95,244,868...95,259,730

G

Cd247 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD247 mRNA

NCBI chr13:80,576,264...80,651,422
Ensembl chr13:80,576,202...80,655,248

G

CD34 molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CD34 mRNA

NCBI chr13:109,008,786...109,029,317
Ensembl chr13:109,008,623...109,029,315

G

CD36 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD36 mRNA

NCBI chr 4:18,209,088...18,302,142

G

CD38 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD38 mRNA

NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505

G

CD44 molecule

multiple interactions
increases expression

ISO
EXP

FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CD44 mRNA]

PMID:12839939 PMID:24160326

NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424

G

Cd47 molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CD47 mRNA

NCBI chr11:64,374,816...64,438,763
Ensembl chr11:64,377,926...64,438,272

G

CD55 molecule (Cromer blood group)

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CD55 mRNA
Asbestos, Crocidolite results in decreased expression of CD55 mRNA

PMID:18687144 PMID:29279043

NCBI chr13:44,409,574...44,438,913
Ensembl chr13:44,409,587...44,438,107

G

CD59b molecule

increases mutagenesis
multiple interactions

ISO

Asbestos, Crocidolite results in increased mutagenesis of CD59 gene
CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased mutagenesis of CD59 gene]

PMID:12361925 PMID:15033018

NCBI chr 3:110,914,008...110,932,489
Ensembl chr 3:110,914,091...110,935,310

G

Cd68 molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CD68 mRNA

NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,880,563...54,882,540

G

Cd72 molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CD72 mRNA

NCBI chr 5:62,493,155...62,500,779
Ensembl chr 5:62,493,161...62,500,519

G

cytidine and dCMP deaminase domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDADC1 mRNA

NCBI chr15:37,902,789...37,934,853
Ensembl chr15:37,886,258...37,931,920

G

codanin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDAN1 mRNA

NCBI chr 3:128,129,664...128,143,520
Ensembl chr 3:128,129,301...128,143,549

G

cell division cycle 123

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDC123 mRNA

NCBI chr17:77,368,376...77,412,659
Ensembl chr17:77,368,397...77,412,659

G

cell division cycle 40

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDC40 mRNA

NCBI chr20:45,855,739...45,908,239
Ensembl chr20:45,855,739...45,907,978

G

cell division cycle 42

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDC42 mRNA

NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:154,839,631...154,876,627

G

cell division cycle 73

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDC73 mRNA

NCBI chr13:57,897,924...58,000,031
Ensembl chr13:57,883,983...57,999,978

G

CUB domain containing protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDCP1 mRNA

NCBI chr 8:131,706,140...131,742,799
Ensembl chr 8:131,706,140...131,742,877

G

cadherin 1

multiple interactions
decreases expression

ISO

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in decreased expression of CDH1 protein]
Asbestos, Crocidolite results in decreased expression of CDH1 mRNA; Asbestos, Crocidolite results in decreased expression of CDH1 protein

PMID:18687144 PMID:22573546 PMID:24160326 PMID:28056339

NCBI chr19:51,402,178...51,471,572
Ensembl chr19:51,402,034...51,471,565

G

cadherin 13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDH13 mRNA

NCBI chr19:63,258,251...64,296,122
Ensembl chr19:63,258,122...64,296,119

G

cadherin 16

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDH16 promoter

NCBI chr19:367,202...377,710
Ensembl chr19:367,274...388,934

G

cadherin 2

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDH2 mRNA
Asbestos, Crocidolite results in increased expression of CDH2 protein

PMID:28056339 PMID:29523930

NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288

G

cadherin 20

affects expression

ISO

Asbestos, Crocidolite affects the expression of CDH20 mRNA

NCBI chr13:21,252,272...21,583,526
Ensembl chr13:21,515,123...21,584,349

G

cadherin 22

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDH22 promoter

NCBI chr 3:174,264,869...174,389,940
Ensembl chr 3:174,264,869...174,390,142

G

cadherin 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDH3 promoter

NCBI chr19:51,303,414...51,353,900
Ensembl chr19:51,300,083...51,354,257

G

cadherin 6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDH6 promoter

NCBI chr 2:63,801,630...63,952,309
Ensembl chr 2:63,806,135...63,952,287

G

cadherin 7

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDH7 promoter

NCBI chr13:27,186,223...27,336,076
Ensembl chr13:27,187,257...27,336,023

G

cyclin-dependent kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDK1 protein modified form

NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455

G

cyclin-dependent kinase 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDK14 mRNA

NCBI chr 4:29,619,237...30,213,651
Ensembl chr 4:29,621,217...30,213,651

G

cyclin-dependent kinase 17

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDK17 mRNA

NCBI chr 7:29,570,982...29,677,613
Ensembl chr 7:29,570,816...29,652,008

G

cyclin-dependent kinase 18

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDK18 promoter

NCBI chr13:46,107,763...46,140,705
Ensembl chr13:46,108,911...46,140,865

G

CDK5 regulatory subunit associated protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDK5RAP1 mRNA

NCBI chr 3:163,189,435...163,333,003
Ensembl chr 3:163,191,056...163,332,908

G

cyclin-dependent kinase 7

affects expression

ISO

Asbestos, Crocidolite affects the expression of CDK7 mRNA

NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485

G

cyclin-dependent kinase-like 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDKL5 mRNA

NCBI chr X:37,566,320...37,796,766
Ensembl chr X:37,566,378...37,796,760

G

cyclin-dependent kinase inhibitor 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDKN1A protein

NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969

G

cyclin-dependent kinase inhibitor 1C

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CDKN1C mRNA
Asbestos, Crocidolite results in decreased expression of CDKN1C mRNA

PMID:25351596 PMID:29279043

NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498

G

cyclin-dependent kinase inhibitor 2A

decreases expression
increases response to substance
multiple interactions
affects response to substance
increases mutagenesis

ISO

Asbestos, Crocidolite results in decreased expression of CDKN2A mRNA alternative form; Asbestos, Crocidolite results in decreased expression of CDKN2A protein alternative form
Asbestos, Crocidolite results in decreased expression of CDKN2A protein; Asbestos, Crocidolite results in decreased expression of CDKN2A protein alternative form
CDKN2A gene mutant form results in increased susceptibility to Asbestos, Crocidolite
[CDKN2A mRNA alternative form affects the susceptibility to Asbestos, Crocidolite] which affects the expression of FAF1 mRNA
Asbestos, Crocidolite results in increased mutagenesis of CDKN2A gene alternative form

PMID:19223589 PMID:21526190 PMID:21570478

NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248

G

CDKN2A interacting protein

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CDKN2AIP mRNA
Asbestos, Crocidolite results in decreased expression of CDKN2AIP mRNA

PMID:18687144 PMID:29279043

NCBI chr16:51,266,613...51,274,051
Ensembl chr16:51,268,896...51,274,049

G

cyclin-dependent kinase inhibitor 2B

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of CDKN2B mRNA
Asbestos, Crocidolite results in decreased expression of CDKN2B mRNA

PMID:25757056 PMID:29523930

NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:109,114,322...109,134,855

G

cysteine dioxygenase type 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CDO1 mRNA

NCBI chr18:41,619,076...41,633,719
Ensembl chr18:41,619,070...41,633,891

G

carnitine deficiency-associated gene expressed in ventricle 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDV3 mRNA

NCBI chr 8:112,812,898...112,826,073
Ensembl chr 8:112,813,952...112,826,056

G

caudal type homeo box 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of CDX2 promoter

NCBI chr12:12,762,769...12,769,246
Ensembl chr12:12,762,904...12,769,246

G

chromodomain Y-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CDYL mRNA

NCBI chr17:29,188,697...29,409,805
Ensembl chr17:29,188,698...29,409,757

G

CEA cell adhesion molecule 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CEACAM1 mRNA
Asbestos, Crocidolite results in decreased expression of CEACAM1 mRNA

PMID:25351596 PMID:29279043

NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:90,171,401...90,187,798

G

CCAAT/enhancer binding protein beta

multiple interactions

ISO

Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to CXCL8 promoter]; Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]]

PMID:8969274 PMID:9378980

NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072

G

CCAAT/enhancer binding protein gamma

affects expression

ISO

Asbestos, Crocidolite affects the expression of CEBPG mRNA

NCBI chr 1:96,820,981...96,829,736
Ensembl chr 1:96,810,214...96,830,283

G

CECR2, histone acetyl-lysine reader

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CECR2 mRNA

NCBI chr 4:155,562,576...155,670,253
Ensembl chr 4:155,562,727...155,666,741

G

CUGBP, Elav-like family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CELF2 mRNA

NCBI chr17:75,813,928...76,639,300
Ensembl chr17:75,813,704...76,636,362

G

cell migration inducing hyaluronidase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEMIP mRNA

NCBI chr 1:147,316,052...147,471,552
Ensembl chr 1:147,316,052...147,471,768

G

cell migration inducing hyaluronidase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CEMIP2 mRNA

NCBI chr 1:228,756,826...228,834,313
Ensembl chr 1:228,757,466...228,832,906

G

centrosomal AT-AC splicing factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CENATAC mRNA

NCBI chr 8:53,632,777...53,639,661
Ensembl chr 8:53,632,044...53,639,650

G

centromere protein A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CENPA mRNA

NCBI chr 6:31,420,062...31,431,703

G

centromere protein C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CENPC1 mRNA

NCBI chr14:22,342,910...22,401,522
Ensembl chr14:22,342,927...22,438,590

G

centromere protein S

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CENPS mRNA

NCBI chr 5:164,847,009...164,856,705

G

centrosomal protein 104

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP104 mRNA

NCBI chr 5:169,817,383...169,849,681
Ensembl chr 5:169,817,182...169,852,695

G

centrosomal protein 126

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP126 mRNA

NCBI chr 8:13,485,211...13,552,711
Ensembl chr 8:13,490,685...13,552,221

G

centrosomal protein 162

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP162 mRNA

NCBI chr 8:97,029,677...97,088,243
Ensembl chr 8:97,029,677...97,088,207

G

centrosomal protein 170

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP170 mRNA

NCBI chr13:91,201,808...91,285,990
Ensembl chr13:91,201,808...91,285,990

G

centrosomal protein 19

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP19 mRNA

NCBI chr11:82,182,868...82,192,134
Ensembl chr11:82,182,868...82,192,032

G

centrosomal protein 295

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP295 mRNA

NCBI chr 8:20,437,967...20,475,968
Ensembl chr 8:20,437,338...20,476,115

G

centrosomal protein 70

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP70 mRNA

NCBI chr 8:108,689,562...108,742,620
Ensembl chr 8:108,689,671...108,742,617

G

centrosomal protein 85-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CEP85L mRNA

PMID:29279043 PMID:29523930

NCBI chr20:33,111,114...33,282,182
Ensembl chr20:33,115,438...33,282,238

G

ceramide transporter 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CERT1 mRNA

NCBI chr 2:29,617,202...29,721,734
Ensembl chr 2:29,617,023...29,721,729

G

carboxylesterase 1D

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CES1 protein

NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449

G

cilia and flagella associated protein 20

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CFAP20 mRNA

NCBI chr19:9,614,265...9,628,612
Ensembl chr19:9,614,721...9,628,612

G

cilia and flagella associated protein 418

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CFAP418 mRNA

NCBI chr 5:28,789,580...28,812,891
Ensembl chr 5:28,792,692...28,812,887

G

complement factor H

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CFH mRNA

NCBI chr13:54,063,079...54,164,523
Ensembl chr13:54,062,531...54,164,532

G

CASP8 and FADD-like apoptosis regulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CFLAR mRNA

NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:67,679,559...67,726,434

G

cell growth regulator with ring finger domain 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CGRRF1 mRNA

NCBI chr15:22,560,902...22,588,815
Ensembl chr15:22,568,332...22,588,811

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of CHAC1 mRNA

NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:126,796,024...126,799,361

G

chromodomain helicase DNA binding protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CHD2 mRNA

NCBI chr 1:136,597,993...136,726,874
Ensembl chr 1:136,599,900...136,710,335

G

chromodomain helicase DNA binding protein 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CHD9 mRNA

NCBI chr19:32,114,379...32,337,488
Ensembl chr19:32,115,920...32,319,042

G

checkpoint kinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CHEK1 protein

NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359

G

calcium homeostasis endoplasmic reticulum protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CHERP mRNA

NCBI chr16:17,401,497...17,414,549
Ensembl chr16:17,401,497...17,414,549

G

chitinase 3 like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CHI3L1 mRNA; Asbestos, Crocidolite results in increased expression of CHI3L1 protein

PMID:21135415 PMID:23917077

NCBI chr13:48,193,839...48,201,822
Ensembl chr13:48,193,800...48,201,825

G

cysteine-rich hydrophobic domain 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CHIC2 mRNA

NCBI chr14:33,511,839...33,546,181
Ensembl chr14:33,511,535...33,548,558

G

choline kinase alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CHKA mRNA

NCBI chr 1:210,506,069...210,554,753
Ensembl chr 1:210,506,056...210,554,752

G

chromatin target of PRMT1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CHTOP mRNA

NCBI chr 2:178,278,848...178,291,142
Ensembl chr 2:178,278,848...178,290,348

G

component of inhibitor of nuclear factor kappa B kinase complex

multiple interactions

ISO

Asbestos, Crocidolite results in increased activity of and results in increased phosphorylation of CHUK protein; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased activity of and results in increased phosphorylation of CHUK protein]

NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273

G

cytosolic iron-sulfur assembly component 2A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CIAO2A mRNA

NCBI chr 8:75,565,620...75,577,542
Ensembl chr 8:75,565,567...75,577,541

G

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CITED1 mRNA

NCBI chr X:71,390,328...71,395,023
Ensembl chr X:71,390,331...71,393,649

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CITED2 mRNA

NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:14,103,457...14,134,782

G

CDKN1A interacting zinc finger protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CIZ1 mRNA

NCBI chr 3:36,055,753...36,071,510
Ensembl chr 3:36,056,370...36,075,192

G

CDC28 protein kinase regulatory subunit 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CKS2 mRNA

NCBI chr17:13,722,360...13,727,519
Ensembl chr17:13,722,361...13,727,519

G

cytoplasmic linker associated protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLASP2 mRNA

NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:122,555,524...122,737,587

G

chloride channel accessory 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLCA1 mRNA

NCBI chr 2:236,599,022...236,624,714
Ensembl chr 2:236,599,022...236,624,714

G

claudin 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of CLDN1 mRNA
Asbestos, Crocidolite results in increased expression of CLDN1 mRNA; Asbestos, Crocidolite results in increased expression of CLDN1 protein

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529

G

claudin 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLDN10 mRNA

NCBI chr15:102,269,858...102,361,589
Ensembl chr15:102,269,858...102,361,589

G

claudin 11

multiple interactions
increases expression

ISO

SETD2 protein affects the reaction [Asbestos, Crocidolite results in increased expression of CLDN11 mRNA]

NCBI chr 2:114,136,234...114,149,539
Ensembl chr 2:114,136,234...114,149,539

G

claudin 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLDN14 mRNA

NCBI chr11:46,701,940...46,799,049
Ensembl chr11:46,701,940...46,799,096

G

claudin 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLDN4 mRNA

NCBI chr12:27,388,160...27,389,958
Ensembl chr12:27,387,981...27,389,958

G

claudin 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLDN7 mRNA

NCBI chr10:55,188,670...55,190,871
Ensembl chr10:55,188,684...55,190,905

G

C-type lectin domain family 1, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLEC1A mRNA

NCBI chr 4:164,561,385...164,588,593
Ensembl chr 4:164,563,374...164,587,269

G

C-type lectin domain family 1, member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLEC1B mRNA

NCBI chr 4:164,533,987...164,542,320
Ensembl chr 4:164,534,055...164,542,867

G

C-type lectin domain containing 9A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLEC9A mRNA

NCBI chr 4:164,546,323...164,561,380
Ensembl chr 4:164,546,311...164,561,380

G

chloride intracellular channel 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLIC3 mRNA

NCBI chr 3:28,670,176...28,672,166
Ensembl chr 3:28,670,229...28,675,723

G

chloride intracellular channel 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLIC5 mRNA

NCBI chr 9:24,208,455...24,310,964
Ensembl chr 9:24,208,456...24,358,780

G

CAP-GLY domain containing linker protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLIP1 mRNA

NCBI chr12:38,571,533...38,678,779
Ensembl chr12:38,571,834...38,678,779

G

CDC-like kinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLK1 mRNA

NCBI chr 9:67,441,962...67,453,180
Ensembl chr 9:67,441,952...67,451,187

G

clock circadian regulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLOCK mRNA

NCBI chr14:32,262,747...32,346,872
Ensembl chr14:32,262,750...32,346,872

G

calsyntenin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLSTN1 protein

NCBI chr 5:165,314,128...165,377,627
Ensembl chr 5:165,314,309...165,377,625

G

calsyntenin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLSTN2 mRNA

NCBI chr 8:106,899,894...107,516,402
Ensembl chr 8:106,899,894...107,040,053

G

clathrin heavy chain

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLTC protein

NCBI chr10:72,014,984...72,073,308
Ensembl chr10:72,014,986...72,070,691

G

clusterin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CLU mRNA

NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860

G

clusterin associated protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CLUAP1 mRNA

NCBI chr10:12,094,346...12,159,440
Ensembl chr10:12,094,346...12,131,693

G

cytidine monophosphate N-acetylneuraminic acid synthetase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CMAS mRNA

NCBI chr 4:177,449,801...177,468,117
Ensembl chr 4:177,449,732...177,476,291

G

chemerin chemokine-like receptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CMKLR2 mRNA

NCBI chr 9:72,077,164...72,111,979
Ensembl chr 9:72,078,608...72,116,257

G

CTD nuclear envelope phosphatase 1 regulatory subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CNEP1R1 mRNA

NCBI chr19:35,106,802...35,121,101
Ensembl chr19:35,106,802...35,121,101

G

cornichon family member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CNIH1 mRNA

NCBI chr15:22,517,755...22,529,651
Ensembl chr15:22,497,340...22,529,578

G

connector enhancer of kinase suppressor of Ras 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of CNKSR1 mRNA

NCBI chr 5:151,731,222...151,742,049
Ensembl chr 5:151,731,224...151,742,203

G

cyclin and CBS domain divalent metal cation transport mediator 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CNNM2 mRNA

NCBI chr 1:255,585,063...255,709,455
Ensembl chr 1:255,585,095...255,704,849

G

CCR4-NOT transcription complex, subunit 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CNOT7 mRNA

NCBI chr16:58,478,882...58,498,046
Ensembl chr16:58,478,900...58,498,046

G

CCR4-NOT transcription complex, subunit 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CNOT8 mRNA

NCBI chr10:42,782,042...42,795,207
Ensembl chr10:42,782,283...42,795,207

G

cannabinoid receptor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CNR1 mRNA

NCBI chr 5:53,204,867...53,230,396
Ensembl chr 5:53,204,260...53,239,252

G

contactin 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CNTN6 mRNA

NCBI chr 4:138,911,090...139,307,339
Ensembl chr 4:138,911,380...139,311,816

G

cytochrome c oxidase assembly factor 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COA8 mRNA

NCBI chr 6:136,593,399...136,618,237
Ensembl chr 6:136,592,787...136,619,602

G

component of oligomeric golgi complex 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of COG1 mRNA
Asbestos, Crocidolite results in decreased expression of COG1 mRNA

PMID:19446018 PMID:29523930

NCBI chr10:99,192,604...99,207,640
Ensembl chr10:99,194,568...99,208,437

G

coilin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COIL mRNA

NCBI chr10:74,286,279...74,307,597
Ensembl chr10:74,286,840...74,307,595

G

collagen type XII alpha 1 chain

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COL12A1 mRNA

NCBI chr 8:89,427,834...89,545,886
Ensembl chr 8:89,427,834...89,545,711

G

collagen type I alpha 1 chain

increases expression
multiple interactions
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of COL1A1 mRNA; Asbestos, Crocidolite results in increased expression of COL1A1 protein
MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL1A1 mRNA]
Asbestos, Crocidolite results in decreased expression of COL1A1 mRNA

PMID:11250057 PMID:18192500 PMID:18687144 PMID:23634900 PMID:28056339

NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460

G

collagen type I alpha 2 chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COL1A2 mRNA

NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995

G

collagen type III alpha 1 chain

increases expression
decreases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of COL3A1 mRNA
Asbestos, Crocidolite results in decreased expression of COL3A1 mRNA
MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL3A1 mRNA]

PMID:11250057 PMID:18192500 PMID:28056339

NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232

G

collagen type IV alpha 5 chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COL4A5 mRNA

NCBI chr X:109,907,251...110,111,214
Ensembl chr X:109,907,346...110,111,214

G

collagen type IV alpha 6 chain

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COL4A6 mRNA

NCBI chr X:109,554,945...109,905,987
Ensembl chr X:109,552,651...109,905,944

G

collagen type V alpha 1 chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COL5A1 mRNA

NCBI chr 3:31,606,475...31,755,097
Ensembl chr 3:31,606,486...31,753,020

G

collagen type V alpha 2 chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COL5A2 mRNA

NCBI chr 9:54,940,768...55,090,151
Ensembl chr 9:54,940,764...55,090,150

G

collagen type VIII alpha 2 chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COL8A2 mRNA

NCBI chr 5:143,870,754...143,897,372
Ensembl chr 5:143,870,742...143,897,884

G

collagen type IX alpha 3 chain

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COL9A3 mRNA

NCBI chr 3:188,089,337...188,112,034
Ensembl chr 3:188,089,403...188,112,270

G

COMM domain containing 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COMMD9 mRNA

NCBI chr 3:108,630,903...108,645,427
Ensembl chr 3:108,630,980...108,666,091

G

cartilage oligomeric matrix protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COMP protein

NCBI chr16:19,081,172...19,089,548
Ensembl chr16:19,081,172...19,089,605

G

catechol-O-methyltransferase domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COMTD1 mRNA

NCBI chr15:2,509,121...2,512,232
Ensembl chr15:2,509,032...2,512,232

G

COP1, E3 ubiquitin ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COP1 mRNA

NCBI chr13:73,954,058...74,095,283
Ensembl chr13:73,963,145...74,095,269

G

COPI coat complex subunit alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COPA mRNA

NCBI chr13:87,078,853...87,119,256
Ensembl chr13:87,078,383...87,119,256

G

COPI coat complex subunit epsilon

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COPE mRNA

NCBI chr16:19,148,832...19,159,052
Ensembl chr16:19,148,832...19,159,212

G

COPI coat complex subunit zeta 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of COPZ1 mRNA
Asbestos, Crocidolite results in decreased expression of COPZ1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 7:136,287,696...136,314,131
Ensembl chr 7:136,288,032...136,314,135

G

coenzyme Q10B

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of COQ10B mRNA
Asbestos, Crocidolite results in increased expression of COQ10B mRNA

PMID:18687144 PMID:29279043

NCBI chr 9:64,048,168...64,068,082
Ensembl chr 9:64,048,103...64,068,322

G

coenzyme Q5, methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COQ5 mRNA

NCBI chr12:46,977,632...46,994,575
Ensembl chr12:46,977,632...46,994,712

G

coenzyme Q7, hydroxylase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COQ7 mRNA

NCBI chr 1:182,270,570...182,285,959
Ensembl chr 1:182,269,399...182,285,508

G

coactosin-like F-actin binding protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COTL1 mRNA

NCBI chr19:64,780,309...64,814,629
Ensembl chr19:64,780,322...64,814,840

G

cytochrome c oxidase assembly factor COX18

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COX18 mRNA

NCBI chr14:18,147,558...18,161,622
Ensembl chr14:18,149,992...18,161,619

G

cytochrome c oxidase subunit 5B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of COX5B mRNA

NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403

G

cytochrome c oxidase subunit 7A2 like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COX7A2L mRNA

NCBI chr 6:16,936,574...16,950,797
Ensembl chr 6:16,936,795...16,950,798

G

cytochrome c oxidase subunit 8C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of COX8C mRNA

NCBI chr 6:127,793,379...127,794,702
Ensembl chr 6:127,793,379...127,794,702

G

ceruloplasmin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CP mRNA

NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087

G

carboxypeptidase A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CPA2 mRNA

NCBI chr 4:60,125,297...60,151,066
Ensembl chr 4:60,118,682...60,183,448

G

cytoplasmic polyadenylation element binding protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CPEB2 mRNA

NCBI chr14:71,999,958...72,056,012
Ensembl chr14:72,002,072...72,052,263

G

cytoplasmic polyadenylation element binding protein 4

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of CPEB4 mRNA
Asbestos, Crocidolite results in increased expression of CPEB4 mRNA

PMID:18687144 PMID:29279043

NCBI chr10:16,222,271...16,284,248
Ensembl chr10:16,225,672...16,283,787

G

copine 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CPNE3 mRNA

NCBI chr 5:37,811,566...37,860,840
Ensembl chr 5:37,811,566...37,861,062

G

cleavage and polyadenylation specific factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CPSF2 mRNA

NCBI chr 6:126,885,417...126,917,634
Ensembl chr 6:126,885,476...126,917,632

G

cleavage and polyadenylation specific factor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CPSF3 mRNA

NCBI chr 6:46,564,855...46,592,776
Ensembl chr 6:46,564,735...46,594,136

G

carboxypeptidase, vitellogenic-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CPVL mRNA

NCBI chr 4:84,311,853...84,422,098
Ensembl chr 4:84,311,854...84,416,033

G

complement C3b/C4b receptor 1 like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CR1L mRNA

NCBI chr13:109,138,132...109,189,068
Ensembl chr13:109,103,235...109,188,869

G

cereblon

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CRBN mRNA

NCBI chr 4:141,255,400...141,276,722
Ensembl chr 4:141,257,243...141,276,038

G

CGRP receptor component

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CRCP mRNA

PMID:29279043 PMID:29523930

NCBI chr12:32,260,108...32,315,116
Ensembl chr12:32,260,143...32,315,237

G

cysteine-rich C-terminal 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CRCT1 mRNA

NCBI chr 2:181,329,392...181,330,877
Ensembl chr 2:181,329,392...181,330,877

G

cAMP responsive element binding protein 1

increases phosphorylation
multiple interactions

ISO

Asbestos, Crocidolite results in increased phosphorylation of CREB1 protein
N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of CREB1 protein]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of CREB1 protein]; U 0126 inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of CREB1 protein]

NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339

G

cAMP responsive element binding protein 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of CREB5 mRNA

NCBI chr 4:83,723,587...84,124,786
Ensembl chr 4:83,723,194...84,120,793

G

cAMP responsive element binding protein-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CREBL2 mRNA

NCBI chr 4:169,404,630...169,430,618
Ensembl chr 4:169,376,495...169,430,611

G

CREB3 regulatory factor

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CREBRF mRNA
Asbestos, Crocidolite results in decreased expression of CREBRF mRNA

PMID:18687144 PMID:29279043

NCBI chr10:16,903,607...16,967,450
Ensembl chr10:16,903,547...16,966,430

G

cAMP responsive element modulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CREM mRNA

NCBI chr17:58,932,011...59,001,160
Ensembl chr17:58,934,147...59,001,160

G

cysteine-rich secretory protein LCCL domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CRISPLD2 mRNA

NCBI chr19:64,961,764...65,020,099
Ensembl chr19:64,961,771...65,020,349

G

CRK like proto-oncogene, adaptor protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of CRKL mRNA

NCBI chr11:97,033,033...97,067,457
Ensembl chr11:97,024,782...97,067,457

G

cytokine receptor-like factor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CRLF3 mRNA

NCBI chr10:65,521,296...65,559,162
Ensembl chr10:65,521,492...65,558,804

G

cornulin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CRNN mRNA

NCBI chr 2:181,427,384...181,432,142
Ensembl chr 2:181,429,481...181,431,993

G

cytotoxic and regulatory T cell molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CRTAM mRNA

NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:50,237,210...50,274,472

G

CREB regulated transcription coactivator 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of CRTC1 mRNA

NCBI chr16:19,022,171...19,080,880
Ensembl chr16:19,022,005...19,080,880

G

cryptochrome circadian regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CRY1 mRNA

NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:20,417,107...20,481,822

G

crystallin, alpha B

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CRYAB mRNA
Asbestos, Crocidolite results in decreased expression of CRYAB mRNA

PMID:25351596 PMID:29279043

NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528

G

crystallin, mu

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CRYM mRNA

NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:183,991,745...184,006,962

G

chromosome segregation 1 like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSE1L mRNA

NCBI chr 3:176,060,183...176,097,909
Ensembl chr 3:176,060,215...176,108,734

G

colony stimulating factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CSF1 mRNA

NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:198,065,405...198,084,468

G

colony stimulating factor 1 receptor

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CSF1R mRNA
Asbestos, Crocidolite results in decreased expression of CSF1R mRNA

PMID:29279043 PMID:29507420

NCBI chr18:56,834,152...56,860,804
Ensembl chr18:56,817,049...56,860,806

G

colony stimulating factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CSF2 mRNA; Asbestos, Crocidolite results in increased expression of CSF2 protein

PMID:11250057 PMID:24160326 PMID:25757056 PMID:29507420

NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,887,692...38,890,031

G

colony stimulating factor 2 receptor subunit alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSF2RA mRNA

NCBI chr14:113,219...118,808
Ensembl chr14:113,225...118,117

G

colony stimulating factor 3

increases expression
multiple interactions
increases secretion

ISO

Asbestos, Crocidolite results in increased expression of CSF3 mRNA
Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CSF3 protein]
Asbestos, Crocidolite results in increased expression of CSF3 protein

PMID:23937860 PMID:24160326 PMID:25757056 PMID:26119930 PMID:29279043 More...

NCBI chr10:84,157,485...84,159,860
Ensembl chr10:84,157,211...84,159,860

G

chondroitin sulfate N-acetylgalactosaminyltransferase 2

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of CSGALNACT2 mRNA
Asbestos, Crocidolite results in decreased expression of CSGALNACT2 mRNA
Asbestos, Crocidolite affects the expression of CSGALNACT2 mRNA

PMID:18687144 PMID:25757056 PMID:29279043

NCBI chr 4:152,944,154...152,981,237
Ensembl chr 4:152,950,028...152,981,220

G

casein kinase 2 alpha 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSNK2A1 mRNA

NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:161,170,405...161,215,698

G

casein kinase 2 beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSNK2B mRNA

NCBI chr20:3,704,833...3,709,999
Ensembl chr20:3,704,904...3,710,525

G

cysteine and serine rich nuclear protein 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of CSRNP1 mRNA
Asbestos, Crocidolite affects the expression of CSRNP1 mRNA

PMID:18687144 PMID:25757056

NCBI chr 8:128,582,364...128,594,163
Ensembl chr 8:128,582,365...128,588,469

G

cystatin domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSTDC2 mRNA

NCBI chr 3:156,756,863...156,789,790
Ensembl chr 3:156,758,291...156,762,038

G

cleavage stimulation factor subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CSTF2 mRNA

NCBI chr X:101,546,809...101,572,760
Ensembl chr X:101,546,819...101,572,764

G

CCCTC-binding factor

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of CTCF mRNA
Asbestos, Crocidolite affects the expression of CTCF mRNA

PMID:17331233 PMID:29279043

NCBI chr19:50,431,478...50,481,013
Ensembl chr19:50,431,689...50,481,012

G

catenin beta 1

multiple interactions
affects expression

ISO

Asbestos, Crocidolite results in increased phosphorylation of and affects the localization of CTNNB1 protein; TNF protein promotes the reaction [Asbestos, Crocidolite affects the localization of CTNNB1 protein]
Asbestos, Crocidolite affects the expression of CTNNB1 mRNA; Asbestos, Crocidolite affects the expression of CTNNB1 protein

PMID:17331233 PMID:21570478 PMID:24160326

NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662

G

catenin, beta like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CTNNBL1 mRNA

NCBI chr 3:166,807,899...166,968,932
Ensembl chr 3:166,807,858...166,968,931

G

catenin delta 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CTNND1 mRNA

NCBI chr 3:90,090,025...90,141,247
Ensembl chr 3:90,090,564...90,141,189

G

cathepsin B

increases secretion
multiple interactions

ISO

Asbestos, Crocidolite results in increased secretion of CTSB protein modified form
Y 27632 inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CTSB protein modified form]

NCBI chr15:41,565,607...41,586,479
Ensembl chr15:41,565,611...41,586,478

G

cathepsin H

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CTSH mRNA

NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:99,488,874...99,509,181

G

cortactin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CTTN mRNA

NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:209,029,048...209,058,211

G

CUE domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CUEDC1 mRNA

NCBI chr10:73,389,798...73,484,914
Ensembl chr10:73,389,841...73,483,749

G

cullin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CUL2 mRNA

NCBI chr17:58,864,274...58,905,447
Ensembl chr17:58,864,274...58,905,132

G

cullin 4A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CUL4A mRNA

NCBI chr16:83,086,688...83,124,503
Ensembl chr16:83,086,921...83,124,457

G

cullin 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CUL7 mRNA

NCBI chr 9:21,816,703...21,830,344
Ensembl chr 9:21,816,703...21,830,344

G

cutA divalent cation tolerance homolog

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CUTA mRNA

NCBI chr20:5,024,816...5,026,446
Ensembl chr20:5,024,816...5,026,631

G

cut-like homeobox 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CUX1 mRNA

NCBI chr12:25,728,393...26,062,497
Ensembl chr12:25,743,733...26,062,497

G

cut-like homeobox 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CUX2 mRNA

NCBI chr12:40,168,402...40,368,303
Ensembl chr12:40,149,292...40,366,528

G

CWC22 spliceosome associated protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CWC22 mRNA

NCBI chr 3:83,222,400...83,271,427
Ensembl chr 3:83,209,194...83,271,513

G

C-X3-C motif chemokine ligand 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CX3CL1 mRNA

NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,233,329...10,242,999

G

C-X3-C motif chemokine receptor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CX3CR1 mRNA

NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:128,654,833...128,685,983

G

CXADR, Ig-like cell adhesion molecule

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXADR mRNA

NCBI chr11:30,469,778...30,516,990
Ensembl chr11:30,469,526...30,516,988

G

C-X-C motif chemokine ligand 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL1 mRNA

PMID:18687144 PMID:24160326 PMID:25351596 PMID:25757056

NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811

G

C-X-C motif chemokine ligand 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL10 mRNA
Asbestos, Crocidolite results in increased expression of CXCL10 mRNA; Asbestos, Crocidolite results in increased expression of CXCL10 protein

PMID:25351596 PMID:26119930 PMID:29507420

NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,989,018...15,991,261

G

C-X-C motif chemokine ligand 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL12 mRNA

NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627

G

C-X-C motif chemokine ligand 16

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL16 mRNA

NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,664,742...55,670,226

G

C-X-C motif chemokine ligand 2

multiple interactions
increases expression

EXP
ISO

[Asbestos, Crocidolite results in increased abundance of Hydrogen Peroxide] which results in increased expression of CXCL2 mRNA
Asbestos, Crocidolite results in increased expression of CXCL2 mRNA

PMID:11764986 PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255

G

C-X-C motif chemokine ligand 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL1 mRNA; Asbestos, Crocidolite results in increased expression of CXCL1 protein

PMID:18687144 PMID:24160326 PMID:25351596 PMID:25757056 PMID:26839332 More...

NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624

G

C-X-C motif chemokine ligand 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL6 mRNA

PMID:24160326 PMID:25757056

NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,594,959...17,596,417

G

C-X-C motif chemokine ligand 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCL9 mRNA

NCBI chr14:16,007,166...16,012,077
Ensembl chr14:16,007,204...16,014,299

G

C-X-C motif chemokine receptor 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCR3 mRNA

NCBI chr X:70,884,293...70,886,944
Ensembl chr X:70,883,958...70,886,871

G

C-X-C motif chemokine receptor 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCR4 mRNA

NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459

G

C-X-C motif chemokine receptor 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CXCR6 mRNA

NCBI chr 8:132,311,834...132,317,001
Ensembl chr 8:132,306,600...132,322,498

G

cytochrome b-561

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYB561 mRNA

NCBI chr10:91,377,866...91,388,548
Ensembl chr10:91,377,866...91,385,097

G

cytochrome b5 type A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYB5A mRNA

NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094

G

cytochrome b5 type B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYB5B mRNA

NCBI chr19:51,972,611...52,006,477
Ensembl chr19:51,972,547...52,026,980

G

cytochrome b5 reductase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYB5R1 mRNA

NCBI chr13:48,401,061...48,407,466
Ensembl chr13:48,399,106...48,407,465

G

cytochrome b5 reductase 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CYB5R3 mRNA

NCBI chr 7:116,186,729...116,204,290
Ensembl chr 7:116,186,729...116,204,306

G

cytochrome b5 reductase 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of CYB5R4 mRNA

NCBI chr 8:96,860,415...96,925,789
Ensembl chr 8:96,861,090...96,926,094

G

cytochrome b-245 alpha chain

multiple interactions

ISO

CYBA protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]

NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214

G

cytochrome b-245 chaperone 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYBC1 mRNA

NCBI chr10:106,997,018...107,003,895
Ensembl chr10:106,997,023...107,003,841

G

cytochrome c, somatic

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYCS mRNA

NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816

G

cytoplasmic FMR1 interacting protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CYFIP1 mRNA

NCBI chr 1:115,842,754...115,935,163
Ensembl chr 1:115,846,661...115,951,292

G

CYLD lysine 63 deubiquitinase

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of CYLD mRNA
Asbestos, Crocidolite results in decreased expression of CYLD mRNA

PMID:18687144 PMID:29279043

NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CYP1A1 mRNA

NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012

G

cytochrome P450, family 20, subfamily a, polypeptide 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP20A1 mRNA

NCBI chr 9:69,249,841...69,299,146
Ensembl chr 9:69,249,844...69,299,291

G

cytochrome P450, family 24, subfamily a, polypeptide 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP24A1 mRNA

NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:179,694,647...179,709,083

G

cytochrome P450, family 2, subfamily b, polypeptide 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP2B10 mRNA

NCBI chr 1:90,780,468...90,859,852

G

cytochrome P450, subfamily 2, polypeptide 11

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CYP2C18 mRNA

NCBI chr 1:246,175,216...246,211,445
Ensembl chr 1:246,174,711...246,211,853

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP2E1 mRNA

NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495

G

cytochrome P450, family 2, subfamily f, polypeptide 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP2F2 mRNA

NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:91,543,768...91,557,553

G

cytochrome P450, family 46, subfamily a, polypeptide 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of CYP46A1 mRNA

NCBI chr 6:133,011,948...133,039,167
Ensembl chr 6:133,011,989...133,041,971

G

cytochrome P450, family 4, subfamily f, polypeptide 18

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYP4F3 mRNA

PMID:18687144 PMID:25351596

NCBI chr16:17,797,558...17,838,958
Ensembl chr16:17,740,001...17,838,958

G

cysteine and tyrosine rich 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of CYYR1 mRNA

NCBI chr11:38,044,003...38,150,391
Ensembl chr11:38,001,699...38,164,473

G

dishevelled associated activator of morphogenesis 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of DAAM1 mRNA
Asbestos, Crocidolite results in decreased expression of DAAM1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 6:96,125,521...96,286,049
Ensembl chr 6:96,125,621...96,286,049

G

DAB adaptor protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DAB1 mRNA

NCBI chr 5:123,621,510...124,742,585
Ensembl chr 5:124,369,415...124,742,584

G

DAB adaptor protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DAB2 mRNA

NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:57,242,064...57,294,888

G

differentiation antagonizing non-protein coding RNA

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DANCR mRNA

NCBI chr14:34,481,052...34,482,032

G

death associated protein kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DAPK1 mRNA

NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,935,625...4,096,581

G

dual adaptor of phosphotyrosine and 3-phosphoinositides 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DAPP1 mRNA

NCBI chr 2:229,099,319...229,148,868
Ensembl chr 2:229,099,319...229,148,843

G

dynein assembly factor with WD repeats 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DAW1 mRNA

NCBI chr 9:91,883,656...91,920,733
Ensembl chr 9:91,881,067...91,921,349

G

death-domain associated protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of DAXX mRNA

NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720

G

DAZ associated protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DAZAP2 mRNA

NCBI chr 7:133,593,503...133,599,044
Ensembl chr 7:133,593,512...133,599,047

G

diazepam binding inhibitor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DBI mRNA

NCBI chr13:33,794,231...33,802,632
Ensembl chr13:33,759,845...33,821,450

G

drebrin-like

affects expression

ISO

Asbestos, Crocidolite affects the expression of DBNL mRNA

NCBI chr14:84,880,085...84,895,122
Ensembl chr14:84,880,142...84,897,133

G

D-box binding PAR bZIP transcription factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DBP mRNA

NCBI chr 1:105,312,256...105,317,205
Ensembl chr 1:105,312,108...105,317,205

G

dihydrolipoamide branched chain transacylase E2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DBT mRNA

NCBI chr 2:207,166,660...207,195,528
Ensembl chr 2:207,166,652...207,195,525

G

DDB1 and CUL4 associated factor 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DCAF10 mRNA

NCBI chr 5:64,402,307...64,442,839
Ensembl chr 5:64,403,451...64,440,614

G

DDB1 and CUL4 associated factor 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DCAF6 mRNA

NCBI chr13:80,159,282...80,260,510
Ensembl chr13:80,159,321...80,260,510

G

doublecortin-like kinase 1

decreases expression
decreases methylation

ISO

Asbestos, Crocidolite results in decreased expression of DCLK1 mRNA
Asbestos, Crocidolite results in decreased methylation of DCLK1 promoter

PMID:25351596 PMID:29626692

NCBI chr 2:141,567,215...141,861,088
Ensembl chr 2:141,571,983...141,861,090

G

decorin

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of DCN mRNA
Asbestos, Crocidolite results in decreased expression of DCN mRNA

PMID:24160326 PMID:29279043

NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926

G

dCTP pyrophosphatase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DCTPP1 mRNA

NCBI chr 1:191,307,933...191,311,326
Ensembl chr 1:191,307,935...191,313,405

G

defective in cullin neddylation 1 domain containing 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DCUN1D5 mRNA

NCBI chr 8:12,697,160...12,718,242
Ensembl chr 8:12,697,127...12,718,991

G

damage-specific DNA binding protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DDB1 mRNA

NCBI chr 1:216,677,810...216,703,605
Ensembl chr 1:216,677,810...216,703,596

G

DNA-damage inducible transcript 3

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of DDIT3 mRNA
Asbestos, Crocidolite results in decreased expression of DDIT3 mRNA
Asbestos, Crocidolite affects the expression of DDIT3 mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509

G

DNA-damage-inducible transcript 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of DDIT4 mRNA

NCBI chr20:28,434,938...28,437,037
Ensembl chr20:28,434,944...28,437,037

G

discoidin domain receptor tyrosine kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DDR2 mRNA

NCBI chr13:84,726,412...84,851,032
Ensembl chr13:84,731,180...84,850,288

G

DEAD-box helicase 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DDX10 mRNA

NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585

G

DEAD-box helicase 24

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DDX24 mRNA

NCBI chr 6:128,329,554...128,346,818
Ensembl chr 6:128,329,554...128,349,625

G

DEAD box helicase 3, Y-linked

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DDX3Y mRNA

NCBI chr Y:1,190,042...1,210,699
Ensembl chr Y:1,191,242...1,210,650

G

DEAD-box helicase 51

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DDX51 mRNA

NCBI chr12:51,671,078...51,675,900
Ensembl chr12:51,671,078...51,676,099

G

DEAD-box helicase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DDX6 mRNA

NCBI chr 8:53,827,661...53,864,538
Ensembl chr 8:53,827,835...53,860,977

G

2,4-dienoyl-CoA reductase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DECR2 mRNA

NCBI chr10:15,609,389...15,617,779
Ensembl chr10:15,611,092...15,617,397

G

defensin beta 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DEFB2 mRNA

NCBI chr16:76,934,341...76,948,284
Ensembl chr16:76,934,337...76,948,299

G

defensin beta 42

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DEFB48 mRNA

NCBI chr15:41,410,651...41,417,610
Ensembl chr15:41,410,651...41,417,610

G

delta(4)-desaturase, sphingolipid 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DEGS2 mRNA

NCBI chr 6:133,360,449...133,377,677
Ensembl chr 6:133,360,457...133,364,422

G

DENN domain containing 4C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DENND4C mRNA

NCBI chr 5:106,316,942...106,421,484
Ensembl chr 5:106,318,281...106,415,489

G

DENN domain containing 5A

affects expression

ISO

Asbestos, Crocidolite affects the expression of DENND5A mRNA

NCBI chr 1:173,362,959...173,428,973
Ensembl chr 1:173,362,959...173,428,926

G

density regulated reinitiation and release factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DENR mRNA

NCBI chr12:38,323,433...38,346,207
Ensembl chr12:38,323,445...38,344,797

G

DEP domain containing 1B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DEPDC1B mRNA

NCBI chr 2:41,605,686...41,697,207
Ensembl chr 2:41,624,922...41,697,202

G

DEP domain containing MTOR-interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DEPTOR mRNA

NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:88,404,620...88,574,041

G

derlin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DERL1 mRNA

NCBI chr 7:91,293,963...91,316,639
Ensembl chr 7:91,258,382...91,316,678

G

desmin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DES mRNA

NCBI chr 9:84,299,626...84,307,344
Ensembl chr 9:84,298,447...84,307,347

G

desumoylating isopeptidase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DESI2 mRNA

NCBI chr13:92,493,765...92,543,307
Ensembl chr13:92,493,989...92,564,981

G

deoxyhypusine synthase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DHPS mRNA

NCBI chr19:39,987,328...39,991,418
Ensembl chr19:39,987,324...39,991,432

G

dehydrogenase/reductase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DHRS2 mRNA

NCBI chr15:32,658,855...32,673,591
Ensembl chr15:32,659,223...32,673,588

G

dehydrogenase/reductase 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DHRS4 mRNA

NCBI chr15:32,924,482...32,948,103
Ensembl chr15:32,936,522...32,948,101

G

dehydrogenase/reductase 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DHRS9 mRNA

NCBI chr 3:74,553,357...74,579,535
Ensembl chr 3:74,555,606...74,581,376

G

DExH-box helicase 57

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DHX57 mRNA

NCBI chr 6:20,474,889...20,528,556
Ensembl chr 6:20,477,191...20,528,556

G

iodothyronine deiodinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DIO1 mRNA

NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771

G

disco-interacting protein 2 homolog A

affects expression

ISO

Asbestos, Crocidolite affects the expression of DIP2A mRNA

NCBI chr20:12,284,037...12,373,519
Ensembl chr20:12,284,038...12,370,532

G

DIX domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DIXDC1 mRNA

NCBI chr 8:59,904,218...59,977,595
Ensembl chr 8:59,904,218...59,978,447

G

dickkopf WNT signaling pathway inhibitor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of DKK1 mRNA

NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650

G

dickkopf WNT signaling pathway inhibitor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DKK3 mRNA

NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186

G

DLG associated protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DLGAP1 mRNA

NCBI chr 9:117,304,144...118,173,463
Ensembl chr 9:117,614,061...118,173,463

G

distal-less homeobox 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DLX2 mRNA

NCBI chr 3:76,777,912...76,781,255
Ensembl chr 3:76,777,912...76,781,255

G

distal-less homeobox 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DLX3 mRNA

NCBI chr10:80,561,335...80,566,730
Ensembl chr10:80,561,335...80,566,711

G

distal-less homeobox 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of DLX4 promoter

NCBI chr10:80,581,878...80,587,272
Ensembl chr10:80,582,303...80,587,294

G

DNA methyltransferase 1-associated protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DMAP1 mRNA

NCBI chr 5:136,380,211...136,388,229
Ensembl chr 5:136,380,216...136,388,219

G

DNA meiotic recombinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DMC1 mRNA

NCBI chr 7:113,005,278...113,047,854
Ensembl chr 7:113,005,281...113,047,854

G

dystrophin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DMD mRNA

NCBI chr X:51,070,098...53,437,845
Ensembl chr X:51,070,273...53,437,835

G

dermokine

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DMKN mRNA

PMID:23917077 PMID:29523930

NCBI chr 1:95,140,737...95,158,676
Ensembl chr 1:95,141,620...95,157,439

G

DM1 protein kinase

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of DMPK promoter

NCBI chr 1:87,858,294...87,868,624
Ensembl chr 1:87,858,316...87,868,910

G

cyclin D binding myb-like transcription factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DMTF1 mRNA

NCBI chr 4:25,864,891...25,905,916
Ensembl chr 4:25,865,447...25,905,943

G

DM1 locus, WD repeat containing

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DMWD mRNA

NCBI chr 1:87,850,475...87,857,263
Ensembl chr 1:87,850,604...87,857,624

G

Dmx-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DMXL2 mRNA

NCBI chr 8:63,637,314...63,803,911
Ensembl chr 8:63,637,314...63,781,116

G

dynein, axonemal, assembly factor 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAAF5 mRNA

NCBI chr12:20,567,482...20,606,600
Ensembl chr12:20,531,267...20,607,607

G

dynein, axonemal, intermediate chain 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAI2 mRNA

NCBI chr10:100,259,022...100,292,427
Ensembl chr10:100,258,994...100,292,426

G

DnaJ heat shock protein family (Hsp40) member A1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAJA1 mRNA
Asbestos, Crocidolite results in decreased expression of DNAJA1 mRNA

PMID:25351596 PMID:29279043

NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:60,638,410...60,650,160

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAJB1 mRNA

NCBI chr19:41,427,453...41,431,141
Ensembl chr19:41,427,453...41,431,416

G

DnaJ heat shock protein family (Hsp40) member B13

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJB13 mRNA

NCBI chr 1:164,260,716...164,275,172
Ensembl chr 1:164,260,724...164,275,093

G

DnaJ heat shock protein family (Hsp40) member B14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJB14 mRNA

NCBI chr 2:229,032,415...229,075,905
Ensembl chr 2:229,032,286...229,075,922

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAJB9 mRNA

NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:66,997,842...67,009,344

G

DnaJ heat shock protein family (Hsp40) member C12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNAJC12 mRNA

NCBI chr20:25,245,475...25,266,238
Ensembl chr20:25,222,298...25,266,251

G

DnaJ heat shock protein family (Hsp40) member C25

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJC25 mRNA

NCBI chr 5:78,620,608...78,642,921
Ensembl chr 5:78,620,581...78,642,920

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJC3 mRNA

NCBI chr15:102,432,667...102,475,643
Ensembl chr15:102,432,663...102,475,643

G

DnaJ heat shock protein family (Hsp40) member C8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJC8 mRNA

NCBI chr 5:150,029,064...150,047,115
Ensembl chr 5:150,026,286...150,047,117

G

DnaJ heat shock protein family (Hsp40) member C9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNAJC9 mRNA

NCBI chr15:3,970,843...4,003,009
Ensembl chr15:3,970,114...3,977,304

G

dynamin 1-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DNM1L mRNA

NCBI chr11:98,084,049...98,135,663
Ensembl chr11:98,085,397...98,137,420

G

dynamin binding protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNMBP mRNA

NCBI chr 1:252,685,406...252,778,642
Ensembl chr 1:252,685,406...252,778,688

G

DNA methyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DNMT1 mRNA; Asbestos, Crocidolite results in increased expression of DNMT1 protein

NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119

G

dedicator of cyto-kinesis 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DOCK1 mRNA

NCBI chr 1:198,897,021...199,413,636
Ensembl chr 1:198,897,045...199,413,627

G

dedicator of cytokinesis 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DOCK10 mRNA

NCBI chr 9:89,291,936...89,549,871
Ensembl chr 9:89,291,800...89,549,973

G

dedicator of cytokinesis 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DOCK4 mRNA

NCBI chr 6:63,240,050...63,629,772
Ensembl chr 6:63,240,136...63,629,772

G

dedicator of cytokinesis 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DOCK6 mRNA

NCBI chr 8:28,618,523...28,670,741
Ensembl chr 8:28,618,523...28,670,648

G

dedicator of cytokinesis 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DOCK7 mRNA

NCBI chr 5:118,714,863...118,898,362
Ensembl chr 5:118,714,863...118,898,335

G

dedicator of cytokinesis 9

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of DOCK9 mRNA
Asbestos, Crocidolite results in decreased expression of DOCK9 mRNA

PMID:25351596 PMID:29279043

NCBI chr15:105,018,341...105,289,799
Ensembl chr15:105,024,912...105,289,799

G

DOP1 leucine zipper like protein A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DOP1A mRNA

NCBI chr 8:96,295,302...96,397,951
Ensembl chr 8:96,295,328...96,398,652

G

DOP1 leucine zipper like protein B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DOP1B mRNA

NCBI chr11:46,494,058...46,595,601
Ensembl chr11:46,494,058...46,595,601

G

DOT1 like histone lysine methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DOT1L mRNA

NCBI chr 7:9,569,439...9,607,095
Ensembl chr 7:9,569,439...9,607,095

G

deleted in primary ciliary dyskinesia

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DPCD mRNA

NCBI chr 1:254,357,755...254,375,918
Ensembl chr 1:254,357,778...254,375,918

G

dipeptidyl peptidase like 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DPP10 mRNA

NCBI chr13:37,145,531...38,821,987
Ensembl chr13:37,145,531...38,822,801

G

dipeptidylpeptidase 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DPP8 mRNA

NCBI chr 8:74,445,815...74,501,017
Ensembl chr 8:74,445,835...74,501,017

G

DNA-damage regulated autophagy modulator 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of DRAM1 mRNA

NCBI chr 7:24,630,233...24,665,270
Ensembl chr 7:24,630,238...24,664,354

G

DNA damage regulated autophagy modulator 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DRAM2 mRNA

NCBI chr 2:196,724,052...196,752,645
Ensembl chr 2:196,723,858...196,755,103

G

dynein regulatory complex subunit 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DRC3 mRNA

NCBI chr10:45,620,045...45,698,902
Ensembl chr10:45,648,410...45,698,900

G

dystonin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DST mRNA

NCBI chr 9:43,631,716...44,025,535
Ensembl chr 9:43,631,517...44,025,533

G

destrin, actin depolymerizing factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DSTN mRNA

NCBI chr 3:151,737,711...151,764,752
Ensembl chr 3:151,737,849...151,764,769

G

dystrobrevin, alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DTNA mRNA

NCBI chr18:14,862,801...15,218,993
Ensembl chr18:14,862,818...15,218,993

G

DTW domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DTWD2 mRNA

NCBI chr18:45,003,242...45,088,595
Ensembl chr18:45,003,644...45,088,419

G

dihydrouridine synthase 4-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DUS4L mRNA

NCBI chr 6:53,955,609...53,970,050
Ensembl chr 6:53,955,609...53,970,087

G

dual specificity phosphatase 1

increases expression
affects response to substance

ISO

Asbestos, Crocidolite results in increased expression of DUSP1 mRNA; Asbestos, Crocidolite results in increased expression of DUSP1 protein
DUSP1 protein affects the susceptibility to Asbestos, Crocidolite

PMID:17322281 PMID:17507666 PMID:18687144 PMID:29523930

NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644

G

dual specificity phosphatase 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DUSP10 mRNA

NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304

G

dual specificity phosphatase 19

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DUSP19 mRNA

NCBI chr 3:85,945,289...86,081,289

G

dual specificity phosphatase 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of DUSP2 mRNA

NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:135,009,590...135,011,809

G

dual specificity phosphatase 22

affects expression

ISO

Asbestos, Crocidolite affects the expression of DUSP22 mRNA

NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,989,637...34,039,895

G

dual specificity phosphatase 4

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of DUSP4 mRNA
Asbestos, Crocidolite results in increased expression of DUSP4 mRNA

PMID:25351596 PMID:25757056

NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700

G

dual specificity phosphatase 5

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of DUSP5 mRNA
Asbestos, Crocidolite affects the expression of DUSP5 mRNA

PMID:18687144 PMID:25757056

NCBI chr 1:262,543,774...262,557,201
Ensembl chr 1:262,543,738...262,562,417

G

dual specificity phosphatase 6

multiple interactions
increases expression
affects expression

ISO

MAPK14 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of DUSP6 protein]; SB 203580 inhibits the reaction [Asbestos, Crocidolite results in increased expression of DUSP6 mRNA]
Asbestos, Crocidolite results in increased expression of DUSP6 mRNA; Asbestos, Crocidolite results in increased expression of DUSP6 protein
Asbestos, Crocidolite affects the expression of DUSP6 mRNA

PMID:17331233 PMID:18314537 PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr 7:35,979,502...35,983,834
Ensembl chr 7:35,977,921...35,983,833

G

dual specificity phosphatase 8

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of DUSP8 mRNA
Asbestos, Crocidolite results in increased expression of DUSP8 mRNA

PMID:17331233 PMID:25351596

NCBI chr 1:206,596,912...206,613,728
Ensembl chr 1:206,598,942...206,612,441

G

dual specificity phosphatase 9

affects expression

ISO

Asbestos, Crocidolite affects the expression of DUSP9 mRNA

NCBI chr X:156,503,237...156,507,162
Ensembl chr X:156,503,190...156,507,161

G

dishevelled segment polarity protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DVL2 mRNA

NCBI chr10:55,222,245...55,231,506
Ensembl chr10:55,222,056...55,231,506

G

dishevelled segment polarity protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DVL3 mRNA

NCBI chr11:93,869,834...93,887,013
Ensembl chr11:93,869,834...93,886,903

G

dynein, cytoplasmic 1 light intermediate chain 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DYNC1LI2 mRNA

NCBI chr19:538,207...561,110
Ensembl chr19:538,211...561,107

G

dynein cytoplasmic 2 heavy chain 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DYNC2H1 mRNA

NCBI chr 8:12,473,955...12,697,075
Ensembl chr 8:12,473,955...12,697,058

G

dynein light chain LC8-type 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DYNLL1 mRNA

NCBI chr12:46,945,291...46,976,867
Ensembl chr12:46,973,050...46,976,861

G

dual specificity tyrosine phosphorylation regulated kinase 1B

affects expression

ISO

Asbestos, Crocidolite affects the expression of DYRK1B mRNA

NCBI chr 1:92,606,743...92,624,089
Ensembl chr 1:92,607,303...92,614,744

G

dysferlin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of DYSF mRNA

NCBI chr 4:118,048,460...118,248,273
Ensembl chr 4:118,047,989...118,248,273

G

double zinc ribbon and ankyrin repeat domains 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of DZANK1 mRNA

NCBI chr 3:152,309,228...152,361,548
Ensembl chr 3:152,309,228...152,361,548

G

E4F transcription factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of E4F1 mRNA

NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,978,990...13,990,506

G

EBF transcription factor 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of EBF1 mRNA
Asbestos, Crocidolite results in decreased expression of EBF1 mRNA

PMID:18687144 PMID:29279043

NCBI chr10:29,597,221...29,990,571
Ensembl chr10:29,601,351...29,988,702

G

endothelin converting enzyme 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ECE1 mRNA

NCBI chr 5:155,361,031...155,462,723
Ensembl chr 5:155,360,639...155,462,719

G

extracellular matrix protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ECM2 mRNA

NCBI chr17:15,326,359...15,358,938
Ensembl chr17:15,326,359...15,358,855

G

Ecm29 proteasome adaptor and scaffold

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ECPAS mRNA
Asbestos, Crocidolite results in decreased expression of ECPAS mRNA

PMID:29279043 PMID:29523930

NCBI chr 5:78,398,449...78,509,077
Ensembl chr 5:78,398,718...78,512,908

G

EGF like repeats and discoidin domains 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EDIL3 protein

NCBI chr 2:21,625,604...22,140,380
Ensembl chr 2:21,625,596...22,140,379

G

endothelin 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of EDN1 mRNA
Asbestos, Crocidolite results in decreased expression of EDN1 mRNA

PMID:25351596 PMID:29523930

NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687

G

early endosome antigen 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EEA1 mRNA

NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:32,441,272...32,608,476

G

eukaryotic translation elongation factor 1 alpha 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EEF1A1 protein

NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:88,221,843...88,225,072

G

EEIG family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EEIG2 mRNA

NCBI chr 2:199,296,582...199,351,449
Ensembl chr 2:199,296,582...199,351,449

G

EGF containing fibulin extracellular matrix protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EFEMP1 protein

NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808

G

elongation factor Tu GTP binding domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EFTUD2 mRNA

NCBI chr10:88,304,992...88,352,229
Ensembl chr10:88,304,992...88,346,299

G

epidermal growth factor

affects expression
multiple interactions

ISO
EXP

Asbestos, Crocidolite affects the expression of EGF mRNA
Asbestos, Crocidolite inhibits the reaction [EGF protein binds to EGFR protein]

PMID:10516208 PMID:17331233

NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297

G

EGF-like-domain, multiple 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EGFL7 mRNA

NCBI chr 3:29,802,481...29,814,966
Ensembl chr 3:29,802,690...29,814,951

G

epidermal growth factor receptor

multiple interactions
increases phosphorylation
increases expression
affects binding
increases activity

ISO
EXP

Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased activity of EGFR protein]; EGFR protein promotes the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; EGFR protein promotes the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]
Asbestos, Crocidolite results in increased phosphorylation of EGFR protein
Asbestos, Crocidolite results in increased expression of EGFR protein
4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of EGFR protein]; Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of EGFR protein]; Cytochalasin B inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein]; Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein]; EGFR protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; EGFR protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; Phytic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of EGFR protein]
Asbestos, Crocidolite binds to EGFR protein
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]; Asbestos, Crocidolite inhibits the reaction [EGF protein binds to EGFR protein]; Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]
Asbestos, Crocidolite results in increased expression of EGFR mRNA; Asbestos, Crocidolite results in increased expression of EGFR protein

PMID:10516208 PMID:10783328 PMID:12154012 PMID:14737115 PMID:15520183 More...

NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358

G

early growth response 1

multiple interactions
affects expression
increases expression

ISO

clinoptilolite inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGR1 mRNA]
Asbestos, Crocidolite affects the expression of EGR1 mRNA

PMID:18687144 PMID:25351596 PMID:25757056 PMID:32123850

NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,736,838...26,740,843

G

early growth response 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EGR2 mRNA

PMID:18687144 PMID:29279043

NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,050,149...21,057,748

G

early growth response 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EGR3 mRNA

NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712

G

early growth response 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EGR4 mRNA

NCBI chr 4:119,605,358...119,607,817
Ensembl chr 4:119,605,357...119,608,368

G

EH-domain containing 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of EHD1 mRNA

NCBI chr 1:213,009,113...213,031,488
Ensembl chr 1:213,008,049...213,031,485

G

ets homologous factor

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of EHF mRNA
Asbestos, Crocidolite results in increased expression of EHF mRNA

PMID:17331233 PMID:24160326

NCBI chr 3:110,094,770...110,134,991
Ensembl chr 3:110,096,756...110,134,928

G

EP300 interacting inhibitor of differentiation 2B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EID2B mRNA

NCBI chr 1:92,673,119...92,674,899

G

eukaryotic translation initiation factor 1B

affects expression

ISO

Asbestos, Crocidolite affects the expression of EIF1B mRNA

NCBI chr 8:129,080,497...129,083,772
Ensembl chr 8:129,078,293...129,083,772
Ensembl chr 5:129,078,293...129,083,772

G

eukaryotic translation initiation factor 3, subunit L

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EIF3L mRNA

NCBI chr 7:112,522,222...112,544,063
Ensembl chr 7:112,507,831...112,544,062

G

eukaryotic translation initiation factor 4B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EIF4B protein

NCBI chr 7:135,085,259...135,107,054
Ensembl chr 7:135,085,066...135,107,064

G

eukaryotic translation initiation factor 4E family member 1B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EIF4E1B mRNA

NCBI chr17:9,835,883...9,868,781
Ensembl chr17:9,836,362...9,860,681

G

eukaryotic translation initiation factor 4E nuclear import factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EIF4ENIF1 mRNA

NCBI chr14:82,280,566...82,328,559
Ensembl chr14:82,280,748...82,323,242

G

eukaryotic translation initiation factor 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EIF5 mRNA

NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821

G

elaC ribonuclease Z 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ELAC1 mRNA

NCBI chr18:69,596,475...69,617,206
Ensembl chr18:69,598,827...69,616,175

G

endosome-lysosome associated apoptosis and autophagy regulator family member 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ELAPOR2 gene

NCBI chr 4:25,565,298...25,760,684
Ensembl chr 4:25,568,122...25,760,684

G

E74 like ETS transcription factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ELF1 mRNA

NCBI chr15:61,354,026...61,395,762
Ensembl chr15:61,330,877...61,395,758

G

E74 like ETS transcription factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ELF2 mRNA

NCBI chr 2:137,445,787...137,536,512
Ensembl chr 2:137,445,788...137,470,355

G

E74 like ETS transcription factor 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ELF5 mRNA

NCBI chr 3:110,264,460...110,291,926
Ensembl chr 3:110,252,797...110,291,926

G

ETS transcription factor ELK1

increases phosphorylation

EXP

[Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of ELK1 protein; [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of ELK1 protein

NCBI chr X:3,692,367...3,709,252
Ensembl chr X:3,693,293...3,709,249

G

ETS transcription factor ELK4

affects expression

ISO

Asbestos, Crocidolite affects the expression of ELK4 mRNA

NCBI chr13:46,004,145...46,027,206
Ensembl chr13:46,004,182...46,027,199

G

elongation factor for RNA polymerase II 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ELL2 mRNA
Asbestos, Crocidolite results in decreased expression of ELL2 mRNA

PMID:18687144 PMID:29279043

NCBI chr 2:6,910,446...6,990,654
Ensembl chr 2:6,921,771...7,016,199

G

elongation factor for RNA polymerase II 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of ELL3 mRNA

NCBI chr 3:128,866,755...128,870,896
Ensembl chr 3:128,864,777...128,870,852

G

elastin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ELN mRNA

NCBI chr12:27,604,983...27,648,413
Ensembl chr12:27,604,680...27,648,413

G

ELOVL fatty acid elongase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ELOVL6 mRNA

NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:220,738,064...220,845,549

G

ELOVL fatty acid elongase 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ELOVL7 mRNA

NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:41,522,738...41,592,020

G

EMG1 N1-specific pseudouridine methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EMG1 mRNA

NCBI chr 4:159,195,545...159,203,826
Ensembl chr 4:159,195,564...159,203,826

G

EMAP like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EML1 mRNA

NCBI chr 6:133,048,271...133,221,642
Ensembl chr 6:133,048,427...133,221,642

G

epithelial membrane protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EMP1 mRNA

PMID:18687144 PMID:25351596

NCBI chr 4:169,931,537...169,964,366
Ensembl chr 4:169,931,440...169,964,365

G

EMSY transcriptional repressor, BRCA2 interacting

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EMSY mRNA

NCBI chr 1:162,295,167...162,364,742
Ensembl chr 1:162,295,169...162,364,707

G

empty spiracles homeobox 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of EMX1 promoter

NCBI chr 4:119,282,692...119,300,822
Ensembl chr 4:119,282,692...119,300,817

G

engrailed homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of EN2 promoter

NCBI chr 4:7,954,953...7,960,793
Ensembl chr 4:7,954,953...7,960,793

G

ectodermal-neural cortex 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ENC1 mRNA

PMID:19446018 PMID:25351596

NCBI chr 2:30,285,274...30,297,194
Ensembl chr 2:30,283,736...30,315,721

G

endonuclease, poly(U)-specific

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ENDOU mRNA

NCBI chr 7:130,723,972...130,745,672
Ensembl chr 7:130,723,972...130,745,672

G

enkurin domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ENKD1 mRNA

NCBI chr19:50,501,963...50,506,447
Ensembl chr19:50,501,963...50,506,942

G

enolase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ENO1 protein

NCBI chr 5:166,002,867...166,014,252
Ensembl chr 3:77,946,261...77,986,003
Ensembl chr 5:77,946,261...77,986,003

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ENPP2 mRNA

NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957

G

E1A binding protein p300

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EP300 mRNA

NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574

G

endothelial PAS domain protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPAS1 mRNA

NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:13,544,389...13,624,729

G

erythrocyte membrane protein band 4.1 like 4A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPB41L4A mRNA

PMID:25351596 PMID:29279043

NCBI chr18:25,680,169...25,890,998
Ensembl chr18:25,680,171...25,888,498

G

erythrocyte membrane protein band 4.1 like 4B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPB41L4B mRNA

NCBI chr 5:76,486,886...76,647,752
Ensembl chr 5:76,486,902...76,647,752

G

enhancer of polycomb homolog 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPC1 mRNA

NCBI chr17:59,198,513...59,289,535
Ensembl chr17:59,197,677...59,289,519

G

ectopic P-granules 5 autophagy tethering factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPG5 mRNA

NCBI chr18:73,679,106...73,776,694
Ensembl chr18:73,679,116...73,776,677

G

Eph receptor A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPHA2 mRNA

NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:158,888,629...158,917,234

G

Eph receptor A4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPHA4 mRNA

NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:86,263,982...86,406,755

G

EPM2A interacting protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPM2AIP1 mRNA

NCBI chr 8:120,112,265...120,119,613
Ensembl chr 8:120,112,084...120,121,458

G

Epsin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPN1 mRNA

NCBI chr 1:77,771,335...77,789,411
Ensembl chr 1:77,771,335...77,789,411

G

epiplakin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPPK1 mRNA

NCBI chr 7:109,697,607...109,718,468
Ensembl chr 7:109,697,607...109,718,468

G

glutamyl-prolyl-tRNA synthetase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EPRS1 mRNA

NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509

G

EGFR pathway substrate 8, signaling adaptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EPS8 mRNA

NCBI chr 4:172,119,497...172,291,670
Ensembl chr 4:172,119,497...172,218,160

G

erb-b2 receptor tyrosine kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ERBB2 protein

NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481

G

epiregulin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EREG mRNA

PMID:18687144 PMID:19446018 PMID:24160326

NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260

G

ER lipid raft associated 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ERLIN2 mRNA

NCBI chr16:71,720,486...71,736,999
Ensembl chr16:71,721,364...71,736,503

G

endoplasmic reticulum metallopeptidase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ERMP1 mRNA

NCBI chr 1:236,801,459...236,835,656
Ensembl chr 1:236,801,466...236,839,197

G

endoplasmic reticulum to nucleus signaling 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ERN2 promoter

NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:186,157,691...186,174,521

G

endoplasmic reticulum oxidoreductase 1 beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ERO1B mRNA

NCBI chr17:92,913,696...92,987,401
Ensembl chr17:92,814,368...92,987,555

G

endoplasmic reticulum protein 44

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ERP44 mRNA

NCBI chr 5:67,313,245...67,406,207
Ensembl chr 5:67,312,098...67,406,444

G

ERBB receptor feedback inhibitor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ERRFI1 mRNA

NCBI chr 5:166,606,841...166,620,124
Ensembl chr 5:166,606,834...166,620,432

G

ESF1 nucleolar pre-rRNA processing protein homolog

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ESF1 mRNA

NCBI chr 3:147,908,405...147,961,567
Ensembl chr 3:147,908,405...147,961,485

G

endothelial cell-specific molecule 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ESM1 mRNA

NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:46,609,204...46,617,990

G

extra spindle pole bodies like 1, separase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ESPL1 mRNA

NCBI chr 7:135,302,460...135,329,570
Ensembl chr 7:135,302,716...135,329,570

G

estrogen-related receptor gamma

affects expression

ISO

Asbestos, Crocidolite affects the expression of ESRRG mRNA

NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877

G

ETAA1 activator of ATR kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ETAA1 mRNA

NCBI chr14:96,500,899...96,515,617
Ensembl chr14:96,500,899...96,517,796

G

electron transfer flavoprotein subunit alpha

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ETFA mRNA

NCBI chr 8:64,731,192...64,787,965
Ensembl chr 8:64,731,193...64,788,080

G

electron transfer flavoprotein subunit beta lysine methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ETFBKMT mRNA

NCBI chr 4:183,871,819...183,936,843
Ensembl chr 4:183,871,827...183,881,621

G

ethanolamine kinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ETNK1 mRNA

NCBI chr 4:177,857,001...177,901,278
Ensembl chr 4:177,856,960...177,924,721

G

ETS proto-oncogene 1, transcription factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ETS1 mRNA

NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:39,303,925...39,426,021

G

ETS variant transcription factor 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ETV4 mRNA

NCBI chr10:87,206,977...87,222,202
Ensembl chr10:87,206,977...87,222,318

G

eva-1 homolog B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EVA1B mRNA

NCBI chr 5:143,711,627...143,716,963
Ensembl chr 5:143,711,395...143,717,551

G

ecotropic viral integration site 5-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EVI5L mRNA

NCBI chr12:7,317,474...7,356,445
Ensembl chr12:7,317,515...7,356,616

G

even-skipped homeobox 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of EVX1 promoter

NCBI chr 4:82,747,192...82,751,569
Ensembl chr 4:82,746,993...82,751,569

G

even-skipped homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of EVX2 promoter

NCBI chr 3:79,965,630...79,969,700
Ensembl chr 3:79,965,630...79,969,305

G

exonuclease 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EXO5 mRNA

NCBI chr 5:139,779,646...139,782,963
Ensembl chr 5:139,777,987...139,783,034

G

exocyst complex component 3-like 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EXOC3L4 mRNA

NCBI chr 6:136,273,857...136,287,877
Ensembl chr 6:136,273,854...136,287,881

G

exocyst complex component 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EXOC7 mRNA

NCBI chr10:102,019,805...102,039,333
Ensembl chr10:102,019,806...102,039,447

G

exosome component 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EXOSC10 mRNA

NCBI chr 5:164,278,414...164,302,067
Ensembl chr 5:164,278,440...164,302,067

G

exosome component 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of EXOSC6 mRNA

NCBI chr19:55,931,523...55,932,937
Ensembl chr19:55,931,523...55,932,937

G

exostosin-like glycosyltransferase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EXTL2 mRNA

NCBI chr 2:206,607,106...206,631,861
Ensembl chr 2:206,607,151...206,631,861

G

EYA transcriptional coactivator and phosphatase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EYA2 mRNA

NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:174,818,554...174,938,034

G

enhancer of zeste 1 polycomb repressive complex 2 subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of EZH1 mRNA

NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620

G

F11 receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of F11R mRNA

NCBI chr13:86,406,229...86,429,819
Ensembl chr13:86,406,218...86,429,816

G

coagulation factor II (thrombin) receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of F2R mRNA

NCBI chr 2:28,604,066...28,620,579
Ensembl chr 2:28,604,066...28,620,579

G

F2R like trypsin receptor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of F2RL1 mRNA

NCBI chr 2:28,507,003...28,519,954
Ensembl chr 2:28,507,003...28,519,954

G

coagulation factor III, tissue factor

multiple interactions
decreases expression
increases expression
increases activity

ISO

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; calphostin complex inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; Lithium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; SB 203580 inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; Staurosporine inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]; U 0126 inhibits the reaction [Asbestos, Crocidolite results in increased expression of F3 mRNA]
Asbestos, Crocidolite results in decreased expression of F3 mRNA
Asbestos, Crocidolite results in increased expression of F3 mRNA; Asbestos, Crocidolite results in increased expression of F3 protein
Asbestos, Crocidolite results in increased activity of F3 protein

PMID:15371228 PMID:15636197 PMID:29279043

NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369

G

fatty acid 2-hydroxylase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FA2H mRNA

NCBI chr19:56,222,240...56,273,480
Ensembl chr19:56,222,242...56,273,623

G

Fas associated factor 1

affects expression
multiple interactions

ISO

Asbestos, Crocidolite affects the expression of FAF1 mRNA
[CDKN2A mRNA alternative form affects the susceptibility to Asbestos, Crocidolite] which affects the expression of FAF1 mRNA

PMID:17331233 PMID:19223589

NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:129,654,445...130,020,516

G

family with sequence similarity 107, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM107A mRNA

NCBI chr15:19,038,726...19,060,644
Ensembl chr15:19,038,616...19,065,219

G

family with sequence similarity 118, member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM118B mRNA

NCBI chr 8:41,824,522...41,875,190
Ensembl chr 8:41,824,158...41,846,256

G

family with sequence similarity 120 member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM120A mRNA

NCBI chr17:15,890,151...15,981,337
Ensembl chr17:15,890,605...15,981,332

G

family with sequence similarity 131, member A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FAM131A mRNA

NCBI chr11:93,715,979...93,725,930
Ensembl chr11:93,716,002...93,725,919

G

family with sequence similarity 131, member C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FAM131C mRNA

NCBI chr 5:158,957,444...158,973,773
Ensembl chr 5:158,957,451...158,974,019

G

family with sequence similarity 149, member B1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM149B1 mRNA

NCBI chr15:3,978,377...4,016,323
Ensembl chr15:3,978,377...4,016,317

G

FAM161 centrosomal protein B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM161B mRNA

NCBI chr 6:109,722,073...109,750,003
Ensembl chr 6:109,722,569...109,750,036

G

family with sequence similarity 171, member A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM171A1 mRNA

NCBI chr17:79,933,742...80,057,495
Ensembl chr17:79,934,050...80,057,495

G

family with sequence similarity 174, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM174A mRNA

NCBI chr 9:103,190,144...103,208,419
Ensembl chr 9:103,190,127...103,209,228

G

family with sequence similarity 174, member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM174B mRNA

NCBI chr 1:136,925,162...137,006,082
Ensembl chr 1:136,925,151...137,035,589

G

family with sequence similarity 193, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM193A mRNA

NCBI chr14:80,480,742...80,607,086
Ensembl chr14:80,480,742...80,607,024

G

family with sequence similarity 199, X-linked

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM199X mRNA

NCBI chr X:105,176,504...105,212,207
Ensembl chr X:105,176,504...105,212,207

G

family with sequence similarity 204, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM204A mRNA

NCBI chr 1:269,323,473...269,352,772
Ensembl chr 1:269,323,473...269,352,772

G

family with sequence similarity 241 member A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FAM241A mRNA

NCBI chr 2:219,019,025...219,049,648
Ensembl chr 2:219,018,241...219,049,770

G

family with sequence similarity 24 member B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FAM24B mRNA

NCBI chr 1:195,542,729...195,546,140
Ensembl chr 1:195,542,729...195,546,140

G

FAM3 metabolism regulating signaling molecule A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FAM3A mRNA

NCBI chr X:157,317,993...157,326,640
Ensembl chr X:157,317,990...157,326,612

G

family with sequence similarity 43, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM43A mRNA

NCBI chr11:83,633,165...83,636,313
Ensembl chr11:83,633,154...83,695,297

G

family with sequence similarity 76, member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM76B mRNA

NCBI chr 8:18,971,357...18,993,442
Ensembl chr 8:18,971,100...18,995,039

G

family with sequence similarity 91, member A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM91A1 mRNA

NCBI chr 7:91,857,261...91,897,019
Ensembl chr 7:91,859,062...91,898,195

G

family with sequence similarity 98, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAM98A mRNA

NCBI chr 6:25,626,108...25,640,767
Ensembl chr 6:25,625,984...25,640,767

G

FA complementation group D2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FANCD2 mRNA

NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:148,234,708...148,299,035

G

FA complementation group G

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FANCG mRNA

NCBI chr 5:62,027,494...62,037,202
Ensembl chr 5:62,027,500...62,035,787

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FARP1 promoter

NCBI chr15:104,531,196...104,770,148
Ensembl chr15:104,531,813...104,770,147

G

Fas cell surface death receptor

increases expression
decreases expression

EXP
ISO

Asbestos, Crocidolite results in increased expression of FAS mRNA
Asbestos, Crocidolite results in decreased expression of FAS mRNA

PMID:12909582 PMID:29279043

NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104

G

FAST kinase domains 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FASTKD5 mRNA

NCBI chr 3:138,283,315...138,300,803
Ensembl chr 3:138,272,928...138,301,291

G

FAT atypical cadherin 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FAT3 promoter

NCBI chr 8:20,972,840...21,555,679
Ensembl chr 8:20,972,840...21,555,240

G

fatty acid hydroxylase domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FAXDC2 mRNA

NCBI chr10:42,747,323...42,772,156
Ensembl chr10:42,747,524...42,781,458

G

F-box DNA helicase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBH1 mRNA

NCBI chr17:71,659,351...71,697,431
Ensembl chr17:71,659,249...71,697,432

G

fibulin 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FBLN5 protein

NCBI chr 6:126,664,100...126,742,847
Ensembl chr 6:126,664,100...126,746,296

G

F-box and leucine-rich repeat protein 14

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FBXL14 mRNA

NCBI chr 4:154,334,820...154,338,638
Ensembl chr 4:154,334,092...154,377,959

G

F-box and leucine-rich repeat protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXL3 mRNA

NCBI chr15:86,321,504...86,341,387
Ensembl chr15:86,321,504...86,341,387

G

F-box and leucine-rich repeat protein 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXL5 mRNA

NCBI chr14:71,517,452...71,559,850
Ensembl chr14:71,480,270...71,560,652

G

F-box protein 22

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FBXO22 mRNA

NCBI chr 8:64,476,034...64,492,063
Ensembl chr 8:64,475,957...64,492,062

G

F-box protein 38

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXO38 mRNA

NCBI chr18:58,227,253...58,274,320
Ensembl chr18:58,227,262...58,274,262

G

F-box protein 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXO4 mRNA

NCBI chr 2:54,902,394...54,915,388
Ensembl chr 2:54,902,394...54,915,388

G

f-box protein 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXO9 mRNA

NCBI chr 8:87,838,787...87,864,362
Ensembl chr 8:87,838,789...87,864,504

G

F-box and WD repeat domain containing 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FBXW11 mRNA

NCBI chr10:17,737,181...17,834,834
Ensembl chr10:17,720,444...17,834,834

G

FCH and mu domain containing endocytic adaptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FCHO2 mRNA

NCBI chr 2:31,813,356...31,916,471
Ensembl chr 2:31,814,950...31,915,445

G

FCH and double SH3 domains 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FCHSD2 mRNA

NCBI chr 1:164,775,916...165,097,391
Ensembl chr 1:164,775,926...165,097,391

G

flap structure-specific endonuclease 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FEN1 protein

NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016

G

FER tyrosine kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FER mRNA

NCBI chr 9:110,967,317...111,274,315
Ensembl chr 9:110,967,390...111,274,315

G

fasciculation and elongation protein zeta 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FEZ1 mRNA

NCBI chr 8:44,733,288...44,778,519
Ensembl chr 8:44,733,300...44,784,097

G

fibrinogen beta chain

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FGB protein

NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:170,692,965...170,705,434

G

fibroblast growth factor 2

increases expression
increases secretion
multiple interactions
affects expression

ISO

Asbestos, Crocidolite results in increased expression of FGF2 mRNA
Asbestos, Crocidolite results in increased secretion of FGF2 protein
IL1RN protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of FGF2 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of FGF2 protein]
[CASP1 protein affects the susceptibility to Asbestos, Crocidolite] which affects the expression of FGF2 protein
Asbestos, Crocidolite affects the expression of FGF2 mRNA

PMID:17331233 PMID:18687144 PMID:28056339

NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:122,164,454...122,224,493

G

Fibroblast growth factor receptor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FGFR1 mRNA

NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855

G

fibroblast growth factor receptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FGFR2 mRNA

NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:194,175,705...194,280,914

G

fibroblast growth factor receptor 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FGFR4 mRNA

NCBI chr17:9,466,686...9,481,423
Ensembl chr17:9,466,692...9,481,389

G

fibrinogen gamma chain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FGG mRNA

PMID:18687144 PMID:29279043

NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:170,652,234...170,661,170

G

fibrinogen-like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FGL1 mRNA

NCBI chr16:57,824,127...57,854,413
Ensembl chr16:57,824,200...57,854,429

G

four and a half LIM domains 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FHL1 mRNA

PMID:29279043 PMID:29523930

NCBI chr X:139,592,794...139,652,290
Ensembl chr X:139,592,604...139,652,282

G

four and a half LIM domains 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of FHL2 mRNA

NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326

G

fin bud initiation factor homolog

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FIBIN mRNA

NCBI chr 3:117,396,973...117,399,244
Ensembl chr 3:117,391,724...117,399,479

G

fidgetin, microtubule severing factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FIGN mRNA

NCBI chr 3:69,045,918...69,169,148
Ensembl chr 3:69,045,050...69,169,988

G

filamin A interacting protein 1-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FILIP1L mRNA

NCBI chr11:56,403,467...56,646,422
Ensembl chr11:56,410,582...56,646,402

G

four-jointed box kinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FJX1 mRNA

PMID:18687144 PMID:29523930

NCBI chr 3:109,229,223...109,231,324
Ensembl chr 3:109,227,170...109,232,479

G

FKBP prolyl isomerase 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FKBP14 mRNA

NCBI chr 4:85,035,840...85,051,917
Ensembl chr 4:85,037,145...85,051,808

G

FKBP prolyl isomerase 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FKBP1B mRNA

NCBI chr 6:33,551,583...33,570,055
Ensembl chr 6:33,558,517...33,568,129

G

FKBP prolyl isomerase family member 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FKBP6 mRNA

NCBI chr12:26,947,443...27,026,913
Ensembl chr12:26,947,384...27,026,913

G

FKBP prolyl isomerase 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FKBP7 mRNA

NCBI chr 3:82,016,647...82,030,913
Ensembl chr 3:82,016,513...82,028,573

G

folliculin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FLCN mRNA

NCBI chr10:45,088,164...45,107,581
Ensembl chr10:45,088,167...45,107,309

G

filamin A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FLNA protein

NCBI chr X:157,159,051...157,185,559
Ensembl chr X:157,159,051...157,182,343

G

flotillin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FLOT1 mRNA

NCBI chr20:2,922,662...2,932,906
Ensembl chr20:2,922,655...2,932,771

G

fibronectin leucine rich transmembrane protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FLRT2 mRNA

NCBI chr 6:120,507,998...120,603,133
Ensembl chr 6:120,507,689...120,609,004

G

fibronectin leucine rich transmembrane protein 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of FLRT3 mRNA

NCBI chr 3:148,448,115...148,461,458
Ensembl chr 3:148,439,354...148,461,650

G

Fms related receptor tyrosine kinase 1

increases secretion
multiple interactions

ISO

Asbestos, Crocidolite results in increased secretion of FLT1 protein
RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased secretion of FLT1 protein]

NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750

G

Fms related receptor tyrosine kinase 3 ligand

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FLT3L mRNA

NCBI chr 1:104,751,518...104,756,925
Ensembl chr 1:104,749,983...104,757,038

G

formin-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FMNL2 mRNA

NCBI chr 3:57,758,236...58,033,832
Ensembl chr 3:57,758,191...58,033,831

G

flavin containing dimethylaniline monoxygenase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FMO1 mRNA

NCBI chr13:77,715,405...77,747,666
Ensembl chr13:77,715,402...77,747,874

G

flavin containing dimethylaniline monoxygenase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FMO2 mRNA

NCBI chr13:77,755,131...77,777,597
Ensembl chr13:77,757,629...77,777,534

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FMO3 mRNA

NCBI chr13:77,838,899...77,868,869
Ensembl chr13:77,842,602...77,861,256

G

fibromodulin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FMOD mRNA

NCBI chr13:48,045,567...48,056,184
Ensembl chr13:47,990,774...48,056,183

G

fragile X messenger ribonucleoprotein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FMR1 mRNA

NCBI chr X:152,284,857...152,322,686
Ensembl chr X:152,284,841...152,322,675

G

fibronectin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FN1 mRNA

PMID:18687144 PMID:23634900

NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137

G

formin binding protein 1-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FNBP1L mRNA

NCBI chr 2:213,331,871...213,432,821
Ensembl chr 2:213,318,662...213,423,051

G

folliculin interacting protein 1

affects expression
decreases expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of FNIP1 mRNA
Asbestos, Crocidolite results in decreased expression of FNIP1 mRNA
Asbestos, Crocidolite results in increased expression of FNIP1 mRNA

PMID:17331233 PMID:18687144 PMID:29279043

NCBI chr10:39,068,432...39,151,552
Ensembl chr10:39,068,445...39,151,552

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

EXP
ISO

Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; calphostin C inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; herbimycin inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; tyrphostin 25 inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]
Asbestos, Crocidolite results in increased expression of FOS; Asbestos, Crocidolite results in increased expression of FOS mRNA
Asbestos, Crocidolite results in increased expression of FOS mRNA; Asbestos, Crocidolite results in increased expression of FOS protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; AG 1879 inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; EGFR protein promotes the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]

PMID:7743507 PMID:8386370 PMID:8679218 PMID:9242432 PMID:9705890 More...

NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598

G

FosB proto-oncogene, AP-1 transcription factor subunit

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of FOSB mRNA
Asbestos, Crocidolite affects the expression of FOSB mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:88,082,127...88,089,477

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions
increases expression
affects expression

ISO
EXP

FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CD44 mRNA]; FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of MET mRNA]
Asbestos, Crocidolite results in increased expression of FOSL1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; AG 1879 inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; GCLM protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]
Asbestos, Crocidolite results in increased expression of FOSL1 mRNA; Asbestos, Crocidolite results in increased expression of FOSL1 protein
Asbestos, Crocidolite affects the expression of FOSL1 mRNA

PMID:10783328 PMID:12839939 PMID:14737115 PMID:15520183 PMID:17616677 More...

NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391

G

FOS like 2, AP-1 transcription factor subunit

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FOSL2 mRNA; Asbestos, Crocidolite results in increased expression of FOSL2 protein

PMID:16966607 PMID:18687144

NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:30,021,916...30,039,406

G

forkhead box A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FOXA1 mRNA

NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:80,800,960...80,871,191

G

forkhead box D1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FOXD1 mRNA

NCBI chr 2:31,436,802...31,439,222
Ensembl chr 2:31,436,813...31,439,399

G

forkhead box D2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXD2 promoter

NCBI chr 5:133,664,760...133,667,483
Ensembl chr 5:133,664,760...133,667,483

G

forkhead box D3

affects expression

ISO

Asbestos, Crocidolite affects the expression of FOXD3 mRNA

NCBI chr 5:119,450,532...119,452,898
Ensembl chr 5:119,450,394...119,452,786

G

forkhead box E3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXE3 promoter

NCBI chr 5:133,681,684...133,683,266
Ensembl chr 5:133,681,702...133,683,266

G

forkhead box G1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXG1 promoter

NCBI chr 6:72,401,582...72,404,392
Ensembl chr 6:72,394,239...72,427,392

G

forkhead box I1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXI1 promoter

NCBI chr10:19,310,466...19,314,405
Ensembl chr10:19,310,482...19,314,405

G

forkhead box I2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXI2 promoter

NCBI chr 1:199,652,703...199,656,503
Ensembl chr 1:199,652,703...199,656,498

G

forkhead box K1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXK1 promoter

NCBI chr12:17,223,599...17,288,564
Ensembl chr12:17,229,430...17,288,564

G

forkhead box K2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FOXK2 mRNA

NCBI chr10:107,040,933...107,090,860
Ensembl chr10:107,040,933...107,195,823

G

forkhead box L1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXL1 promoter

NCBI chr19:66,105,953...66,109,366

G

forkhead box N3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FOXN3 promoter

NCBI chr 6:124,191,695...124,572,070
Ensembl chr 6:124,195,701...124,572,040

G

forkhead box O1

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of FOXO1 protein

NCBI chr 2:138,462,974...138,541,420
Ensembl chr 2:138,462,697...138,541,419

G

forkhead box O3

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of FOXO3 mRNA
Asbestos, Crocidolite results in decreased expression of FOXO3 mRNA

PMID:17331233 PMID:29279043

NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845

G

forkhead box P1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FOXP1 mRNA

NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:133,122,055...133,500,272

G

FRA10A associated CGG repeat 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FRA10AC1 mRNA

NCBI chr 1:245,381,538...245,413,879
Ensembl chr 1:245,366,451...245,414,189

G

FERM domain containing 6

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of FRMD6 mRNA
Asbestos, Crocidolite results in decreased expression of FRMD6 mRNA

PMID:18687144 PMID:29279043

NCBI chr 6:95,081,958...95,155,561
Ensembl chr 6:95,081,985...95,155,560

G

FERM domain containing 8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of FRMD8 mRNA

NCBI chr 1:212,572,534...212,593,181
Ensembl chr 1:212,572,537...212,592,695

G

FRY microtubule binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FRY mRNA

NCBI chr12:9,530,360...9,773,391
Ensembl chr12:9,530,360...9,897,603

G

fibronectin type III and SPRY domain containing 1-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FSD1L mRNA

NCBI chr 5:73,052,565...73,130,292
Ensembl chr 5:73,054,274...73,130,292

G

follistatin

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of FST mRNA
Asbestos, Crocidolite results in increased expression of FST mRNA

PMID:18687144 PMID:24160326 PMID:25351596 PMID:25757056 PMID:29523930

NCBI chr 2:47,856,345...47,863,670
Ensembl chr 2:47,856,345...47,863,491

G

alpha-L-fucosidase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FUCA2 mRNA

NCBI chr 1:9,706,121...9,720,910
Ensembl chr 1:9,706,094...9,721,706

G

FUN14 domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of FUNDC2 mRNA

NCBI chr18:142,829...155,123
Ensembl chr18:142,640...155,674

G

FXYD domain-containing ion transport regulator 1

decreases expression
decreases methylation

ISO

Asbestos, Crocidolite results in decreased expression of FXYD1 mRNA
Asbestos, Crocidolite results in decreased methylation of FXYD1 promoter

PMID:29279043 PMID:29626692

NCBI chr 1:95,414,556...95,418,645
Ensembl chr 1:95,414,557...95,418,591

G

FXYD domain-containing ion transport regulator 6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of FXYD6 promoter

NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:54,575,591...54,602,715

G

G0/G1switch 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of G0S2 mRNA

PMID:24160326 PMID:25757056

NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293

G

G3BP stress granule assembly factor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of G3BP1 mRNA

NCBI chr10:40,087,533...40,120,931
Ensembl chr10:40,087,533...40,120,931

G

G3BP stress granule assembly factor 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of G3BP2 mRNA

NCBI chr14:16,216,684...16,304,828
Ensembl chr14:16,248,744...16,304,823

G

glucose-6-phosphate dehydrogenase

decreases activity
multiple interactions

ISO

Asbestos, Crocidolite results in decreased activity of G6PD protein
Asbestos, Crocidolite binds to and results in decreased activity of G6PD protein

PMID:11978496 PMID:18370412

NCBI chr X:157,352,364...157,372,144
Ensembl chr X:157,352,373...157,372,144

G

GABA type A receptor associated protein like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GABARAPL2 mRNA

NCBI chr19:56,819,826...56,830,662
Ensembl chr19:56,819,791...56,830,660

G

GA binding protein transcription factor subunit beta 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GABPB1 mRNA

NCBI chr 3:134,333,339...134,380,239
Ensembl chr 3:134,333,339...134,361,344

G

GA binding protein transcription factor subunit beta 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GABPB2 mRNA

NCBI chr 2:185,444,309...185,484,200
Ensembl chr 2:185,450,296...185,483,589

G

gamma-aminobutyric acid type A receptor subunit alpha 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GABRA3 mRNA

NCBI chr X:155,301,979...155,543,870
Ensembl chr X:155,303,928...155,543,863

G

growth arrest and DNA-damage-inducible, alpha

increases expression

ISO
EXP

Asbestos, Crocidolite results in increased expression of GADD45A mRNA

PMID:12839939 PMID:18687144 PMID:29523930

NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807

G

growth arrest and DNA-damage-inducible, beta

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GADD45B mRNA

PMID:18687144 PMID:25351596

NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718

G

cyclin G associated kinase

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of GAK promoter

NCBI chr14:1,234,272...1,308,492
Ensembl chr14:1,234,266...1,323,974

G

polypeptide N-acetylgalactosaminyltransferase 11

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GALNT11 mRNA

NCBI chr 4:10,571,464...10,604,974
Ensembl chr 4:10,571,464...10,604,974

G

polypeptide N-acetylgalactosaminyltransferase 17

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GALNT17 mRNA

NCBI chr12:30,959,460...31,418,150
Ensembl chr12:30,959,447...31,418,149

G

guanidinoacetate N-methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GAMT mRNA

NCBI chr 7:10,099,267...10,102,083
Ensembl chr 7:10,098,571...10,102,083

G

glucosidase II alpha subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GANAB mRNA

NCBI chr 1:215,222,918...215,242,808
Ensembl chr 1:215,222,995...215,243,036

G

growth associated protein 43

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GAP43 mRNA

NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

ISO
EXP

Asbestos, Crocidolite results in increased expression of GAPDH protein
Asbestos, Crocidolite results in increased expression of GAPDH mRNA

PMID:8025751 PMID:29553831

NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:159,648,592...159,653,377

G

growth arrest-specific 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GAS2 mRNA

NCBI chr 1:110,587,952...110,721,572
Ensembl chr 1:110,717,312...110,718,541

G

growth arrest specific 8

affects expression

ISO

Asbestos, Crocidolite affects the expression of DRC4 mRNA

NCBI chr19:68,461,280...68,480,810
Ensembl chr19:68,461,304...68,480,806

G

GATA binding protein 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of GATA4 mRNA

NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609

G

GATA binding protein 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GATA6 mRNA

NCBI chr18:2,460,909...2,492,322
Ensembl chr18:2,458,253...2,492,322

G

GRIP and coiled-coil domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GCC1 mRNA

NCBI chr 4:57,996,261...58,008,126
Ensembl chr 4:57,996,267...58,002,185

G

GTP cyclohydrolase I feedback regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GCHFR mRNA

NCBI chr 3:126,611,892...126,615,926
Ensembl chr 3:126,613,240...126,615,926

G

glutamate-cysteine ligase, catalytic subunit

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of GCLC mRNA; Asbestos, Crocidolite results in increased expression of GCLC protein
[GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]

NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893

G

glutamate cysteine ligase, modifier subunit

multiple interactions
increases expression

ISO

[GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]; GCLM protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]; GCLM protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]
Asbestos, Crocidolite results in increased expression of GCLM mRNA

NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003

G

growth differentiation factor 15

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of GDF15 mRNA
Asbestos, Crocidolite affects the expression of GDF15 mRNA

PMID:18687144 PMID:25757056

NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,838,436...18,842,022

G

GDP dissociation inhibitor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GDI2 mRNA

NCBI chr17:71,559,460...71,586,147
Ensembl chr17:71,559,461...71,586,147

G

glycerophosphodiester phosphodiesterase domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GDPD1 mRNA

NCBI chr10:72,318,716...72,381,143
Ensembl chr10:72,337,778...72,381,120

G

GTP binding protein overexpressed in skeletal muscle

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of GEM mRNA
Asbestos, Crocidolite results in increased expression of GEM mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr 5:30,011,641...30,022,554
Ensembl chr 5:30,011,592...30,022,542

G

guided entry of tail-anchored proteins factor 3, ATPase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GET3 mRNA

NCBI chr19:40,034,675...40,043,064
Ensembl chr19:40,034,967...40,043,061

G

glutamine-fructose-6-phosphate transaminase 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of GFPT2 mRNA
Asbestos, Crocidolite results in decreased expression of GFPT2 mRNA

PMID:24160326 PMID:29279043

NCBI chr10:34,616,146...34,662,420
Ensembl chr10:34,615,370...34,662,419

G

geranylgeranyl diphosphate synthase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GGPS1 mRNA

NCBI chr17:55,958,750...55,982,762
Ensembl chr17:55,958,755...55,971,709

G

gamma-glutamyltransferase 1

multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of and results in increased activity of GGT1 protein

NCBI chr20:13,074,141...13,103,551
Ensembl chr20:13,074,141...13,088,050

G

growth hormone receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GHR mRNA

PMID:25351596 PMID:29279043

NCBI chr 2:54,269,066...54,532,595
Ensembl chr 2:54,270,206...54,532,331

G

GID complex subunit 8 homolog

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GID8 mRNA

NCBI chr 3:188,203,571...188,214,324
Ensembl chr 3:188,203,619...188,212,270

G

GRB10 interacting GYF protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GIGYF2 mRNA

NCBI chr 9:95,449,143...95,574,927
Ensembl chr 9:95,449,167...95,574,927

G

glycerol kinase

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of GK mRNA
Asbestos, Crocidolite results in decreased expression of GK mRNA

PMID:25757056 PMID:29279043

NCBI chr X:54,106,708...54,189,940
Ensembl chr X:54,112,214...54,196,701

G

glucocorticoid induced 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GLCCI1 mRNA

NCBI chr 4:37,274,271...37,601,898
Ensembl chr 4:37,529,364...37,599,802
Ensembl chr 4:37,529,364...37,599,802

G

GLIS family zinc finger 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of GLIS1 mRNA
Asbestos, Crocidolite results in increased expression of GLIS1 mRNA

PMID:17331233 PMID:29279043

NCBI chr 5:127,450,934...127,640,929
Ensembl chr 5:127,451,293...127,640,928

G

GLIS family zinc finger 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of GLIS3 mRNA

NCBI chr 1:235,389,567...235,809,416
Ensembl chr 1:235,392,651...235,809,221

G

glomulin, FKBP associated protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GLMN mRNA

NCBI chr14:2,332,052...2,375,366
Ensembl chr14:2,332,497...2,375,695

G

glucagon-like peptide 2 receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GLP2R mRNA

NCBI chr10:52,901,707...52,964,961
Ensembl chr10:52,900,706...52,964,961

G

glutaredoxin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GLRX2 mRNA

NCBI chr13:58,032,199...58,055,061
Ensembl chr13:58,032,401...58,043,150

G

glutaminase

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of GLS mRNA
Asbestos, Crocidolite results in decreased expression of GLS mRNA

PMID:25351596 PMID:29279043

NCBI chr 9:56,836,584...56,908,861
Ensembl chr 9:56,836,584...56,908,861

G

glutamate-ammonia ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GLUL mRNA

NCBI chr13:68,519,500...68,585,554
Ensembl chr13:68,576,067...68,585,520

G

glia maturation factor, gamma

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GMFG mRNA

NCBI chr 1:92,856,154...92,866,722
Ensembl chr 1:92,854,995...92,866,723

G

G protein subunit alpha i1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GNAI1 mRNA

NCBI chr 4:17,706,061...17,790,176
Ensembl chr 4:17,706,025...17,789,198

G

G protein subunit alpha L

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GNAL mRNA

NCBI chr18:62,892,257...63,032,510
Ensembl chr18:62,892,226...63,043,129

G

G protein subunit alpha o1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GNAO1 mRNA

NCBI chr19:11,040,788...11,198,437
Ensembl chr19:11,040,788...11,198,437

G

G protein subunit beta 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GNB1 mRNA

NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488

G

G protein subunit gamma 11

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of GNG11 mRNA
Asbestos, Crocidolite results in decreased expression of GNG11 mRNA

PMID:28056339 PMID:29279043 PMID:29523930

NCBI chr 4:32,977,681...32,983,121
Ensembl chr 4:32,977,664...32,984,438

G

G protein subunit gamma 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GNG7 mRNA

NCBI chr 7:9,348,148...9,411,924
Ensembl chr 7:9,348,218...9,411,923

G

G protein subunit gamma transducin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GNGT2 mRNA

NCBI chr10:81,271,916...81,280,980
Ensembl chr10:81,277,423...81,280,970

G

glucosamine-6-phosphate deaminase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GNPDA1 mRNA

NCBI chr18:30,416,599...30,428,630
Ensembl chr18:30,416,607...30,428,630

G

glucosamine-6-phosphate deaminase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GNPDA2 mRNA

NCBI chr14:38,874,611...38,892,688
Ensembl chr14:38,874,647...38,892,683

G

golgi integral membrane protein 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GOLIM4 mRNA

NCBI chr 2:162,939,429...163,031,901
Ensembl chr 2:162,939,429...163,031,901

G

golgi phosphoprotein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GOLPH3 mRNA

NCBI chr 2:63,072,610...63,103,091
Ensembl chr 2:63,074,256...63,113,577

G

golgi transport 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GOLT1B mRNA

NCBI chr 4:177,064,071...177,077,165
Ensembl chr 4:177,064,073...177,077,164

G

golgi reassembly stacking protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GORASP2 mRNA

NCBI chr 3:75,882,607...75,911,322
Ensembl chr 3:75,882,515...75,911,328

G

glutamic-oxaloacetic transaminase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GOT1 mRNA

NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871

G

glycerol-3-phosphate acyltransferase, mitochondrial

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPAM mRNA

NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911

G

G patch domain containing 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GPATCH4 mRNA

NCBI chr 2:175,797,503...175,816,547
Ensembl chr 2:175,807,682...175,817,358

G

glypican 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GPC1 protein

NCBI chr 9:100,843,645...100,871,458
Ensembl chr 9:100,843,645...100,879,933

G

glypican 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPC4 mRNA

NCBI chr X:136,565,536...136,676,142
Ensembl chr X:136,565,591...136,676,057

G

glycerophosphocholine phosphodiesterase 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of GPCPD1 mRNA
Asbestos, Crocidolite results in decreased expression of GPCPD1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 3:140,240,574...140,285,469
Ensembl chr 3:140,240,575...140,285,372

G

glycerol-3-phosphate dehydrogenase 1 like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPD1L mRNA

PMID:25351596 PMID:29279043

NCBI chr 8:123,469,282...123,498,948
Ensembl chr 8:123,466,667...123,498,908

G

glucose-6-phosphate isomerase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GPI mRNA

NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:95,965,396...95,993,261

G

glycoprotein nmb

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GPNMB protein

NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:79,341,021...79,380,240

G

G protein-coupled receptor 183

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPR183 mRNA

NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977

G

G protein-coupled receptor 75

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GPR75 mRNA

NCBI chr14:108,810,462...108,821,926
Ensembl chr14:108,817,086...108,821,926

G

G protein-coupled receptor associated sorting protein family member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of BHLHB9 mRNA

NCBI chr X:103,639,366...103,644,561
Ensembl chr X:103,609,243...103,650,463

G

G protein-coupled receptor, class C, group 5, member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPRC5A mRNA

NCBI chr 4:169,634,896...169,653,627
Ensembl chr 4:169,634,748...169,653,625

G

G protein pathway suppressor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of GPS1 mRNA

NCBI chr10:106,548,646...106,553,729
Ensembl chr10:106,548,018...106,554,013

G

G protein pathway suppressor 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of GPS2 mRNA

NCBI chr10:55,136,043...55,139,106
Ensembl chr10:55,136,169...55,139,862

G

glutathione peroxidase 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GPX8 mRNA

NCBI chr 2:46,409,646...46,413,401
Ensembl chr 2:46,409,139...46,413,406

G

GRB2-related adaptor protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of GRAP mRNA

NCBI chr10:46,798,423...46,851,524
Ensembl chr10:46,832,390...46,851,523

G

GRB2-related adaptor protein 2

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of GRAP2 mRNA
Asbestos, Crocidolite results in decreased expression of GRAP2 mRNA

PMID:17331233 PMID:29279043

NCBI chr 7:113,997,356...114,071,073
Ensembl chr 7:113,997,307...114,075,367

G

growth factor receptor bound protein 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of GRB2 mRNA

NCBI chr10:101,380,354...101,448,138
Ensembl chr10:101,380,356...101,448,138

G

gremlin 1, DAN family BMP antagonist

multiple interactions
increases expression
affects localization

ISO

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of GREM1 mRNA]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Asbestos, Crocidolite results in increased expression of GREM1 mRNA]; U 0126 inhibits the reaction [Asbestos, Crocidolite results in increased expression of GREM1 mRNA]
Asbestos, Crocidolite results in increased expression of GREM1 mRNA; Asbestos, Crocidolite results in increased expression of GREM1 protein
Asbestos, Crocidolite affects the localization of GREM1 protein

PMID:17975199 PMID:18687144 PMID:25757056

NCBI chr 3:120,966,639...120,978,319
Ensembl chr 3:120,966,623...120,979,089

G

glutamate ionotropic receptor AMPA type subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GRIA1 mRNA

NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,711,080...42,030,309

G

glutamate ionotropic receptor AMPA type subunit 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GRIA3 mRNA

NCBI chr X:125,103,975...125,369,690
Ensembl chr X:125,103,782...125,369,679

G

glutamate ionotropic receptor NMDA type subunit 2B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GRIN2B mRNA

NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:170,322,617...170,773,570

G

glutamate receptor interacting protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of GRIP1 mRNA

NCBI chr 7:56,820,501...57,477,877
Ensembl chr 7:56,820,704...57,468,417

G

GRIP1 associated protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GRIPAP1 mRNA

NCBI chr X:17,350,817...17,380,626
Ensembl chr X:17,350,819...17,380,588

G

G protein-coupled receptor kinase 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GRK5 mRNA

NCBI chr 1:270,014,314...270,208,294
Ensembl chr 1:270,014,282...270,204,928

G

glutamate metabotropic receptor 7

affects expression

ISO

Asbestos, Crocidolite affects the expression of GRM7 mRNA

NCBI chr 4:145,286,714...146,169,099
Ensembl chr 4:145,286,924...146,169,201

G

glutamate metabotropic receptor 8

affects expression

ISO

Asbestos, Crocidolite affects the expression of GRM8 mRNA

NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:56,770,771...57,687,639

G

goosecoid homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of GSC2 promoter

NCBI chr11:96,576,424...96,578,412
Ensembl chr11:96,575,600...96,578,412

G

glycogen synthase kinase 3 beta

decreases phosphorylation
decreases expression

ISO

Asbestos, Crocidolite results in decreased phosphorylation of GSK3B protein
Asbestos, Crocidolite results in decreased expression of GSK3B mRNA

PMID:17191120 PMID:29523930

NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249

G

glutathione-disulfide reductase

decreases activity

EXP

Asbestos, Crocidolite results in decreased activity of GSR protein

NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394

G

glutathione S-transferase alpha 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GSTA4 mRNA

NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488

G

glutathione S-transferase pi 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GSTP1 mRNA

NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705

G

glutathione S-transferase zeta 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GSTZ1 mRNA

NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233

G

GTF2I repeat domain containing 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of GTF2IRD1 promoter

NCBI chr12:27,890,594...27,997,506
Ensembl chr12:27,890,675...27,997,494

G

general transcription factor IIIC subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GTF3C2 mRNA

NCBI chr 6:30,913,263...30,941,305
Ensembl chr 6:30,923,106...30,940,465

G

G-2 and S-phase expressed 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GTSE1 mRNA

NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661

G

guanylate cyclase 1 soluble subunit alpha 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GUCY1A1 mRNA

NCBI chr 2:169,716,684...169,780,360
Ensembl chr 2:169,716,709...169,779,737

G

guanylate cyclase 2E

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of GUCY2E mRNA]

NCBI chr10:54,453,753...54,478,639
Ensembl chr10:54,457,844...54,472,898

G

glycogenin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GYG1 mRNA

NCBI chr 2:104,540,927...104,583,038
Ensembl chr 2:104,540,533...104,582,818

G

glycophorin C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of GYPC mRNA

NCBI chr18:24,434,921...24,467,592
Ensembl chr18:24,434,922...24,440,053

G

granzyme B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of GZMB mRNA

NCBI chr15:34,459,007...34,462,469
Ensembl chr15:34,459,007...34,462,469

G

H1.0 linker histone

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H1-0 mRNA

NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:112,473,222...112,475,006

G

H1.2 linker histone, cluster member

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H1-2 mRNA

NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317

G

H2A clustered histone 18

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H2AC18 mRNA

NCBI chr 2:186,497,271...186,497,865

G

H2A clustered histone 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H2AC6 mRNA

NCBI chr17:47,403,701...47,404,167

G

H2A.X variant histone

decreases expression
increases secretion

ISO

Asbestos, Crocidolite results in decreased expression of H2AX protein
Asbestos, Crocidolite results in increased secretion of H2AX protein

PMID:38301883 PMID:38605572

NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079

G

H2B clustered histone 14

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H2BC5 mRNA

NCBI chr17:47,488,627...47,489,008

G

H2B clustered histone 6

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of H2BC6 mRNA
Asbestos, Crocidolite results in increased expression of H2BC6 mRNA

PMID:25351596 PMID:29279043

NCBI chr17:41,948,813...41,949,276
Ensembl chr17:47,392,229...47,449,312

G

H2B clustered histone 8

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of H2BC8 mRNA
Asbestos, Crocidolite results in decreased expression of H2BC8 mRNA

PMID:25351596 PMID:29279043

NCBI chr17:47,404,405...47,405,155

G

H2B clustered histone 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H2BC9 mRNA

NCBI chr17:47,166,372...47,174,369

G

H3.3 histone A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of H3F3A mRNA

NCBI chr13:95,065,085...95,076,695
Ensembl chr13:95,065,085...95,076,695

G

H3.4 histone, cluster member

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H3F4 mRNA

NCBI chr10:44,240,282...44,240,842

G

H1.3 linker histone, cluster member

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H1-3 mRNA

NCBI chr17:41,979,562...41,980,341
Ensembl chr17:41,796,116...41,980,485

G

3-hydroxyacyl-CoA dehydratase 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of HACD3 mRNA

NCBI chr 8:74,396,441...74,433,700
Ensembl chr 8:74,396,442...74,433,700

G

3-hydroxyacyl-CoA dehydratase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HACD4 mRNA

NCBI chr 5:107,935,514...107,961,271
Ensembl chr 5:107,934,937...107,962,836

G

HUWE1 associated protein modifying stress responses

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HAPSTR1 mRNA

NCBI chr10:7,252,737...7,281,678
Ensembl chr10:7,252,737...7,281,678

G

hyaluronan synthase 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of HAS1 mRNA

NCBI chr 1:67,366,460...67,378,686
Ensembl chr 1:67,366,460...67,378,444

G

hyaluronan synthase 2

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of HAS2 mRNA
Asbestos, Crocidolite results in increased expression of HAS2 mRNA

PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr 7:90,002,929...90,028,933
Ensembl chr 7:90,002,929...90,018,535

G

heparin-binding EGF-like growth factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HBEGF mRNA

NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220

G

host cell factor C2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HCFC2 mRNA

NCBI chr 7:22,875,440...22,907,391
Ensembl chr 7:22,864,278...22,907,322

G

hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of HCN2 mRNA]

NCBI chr 7:10,620,422...10,639,457
Ensembl chr 7:10,620,422...10,639,457

G

histone deacetylase 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HDAC11 mRNA

NCBI chr 4:125,203,044...125,224,584
Ensembl chr 4:125,202,299...125,224,582

G

helicase, POLQ-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HELQ mRNA

NCBI chr14:9,122,978...9,167,310
Ensembl chr14:9,122,978...9,167,310

G

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HERC1 mRNA

NCBI chr 8:75,796,347...75,965,347
Ensembl chr 8:75,796,357...75,965,347

G

HECT and RLD domain containing E3 ubiquitin protein ligase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HERC2 mRNA

NCBI chr 1:116,009,681...116,243,888
Ensembl chr 1:116,040,736...116,243,884

G

HECT and RLD domain containing E3 ubiquitin protein ligase 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HERC4 mRNA

NCBI chr20:25,329,005...25,403,443
Ensembl chr20:25,328,822...25,403,372

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of HERPUD1 mRNA
Asbestos, Crocidolite results in decreased expression of HERPUD1 mRNA

PMID:18687144 PMID:29279043

NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,604,362...10,624,081

G

HERPUD family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HERPUD2 mRNA

NCBI chr 8:31,849,216...31,894,219
Ensembl chr 8:31,849,216...31,894,219

G

hes family bHLH transcription factor 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HES5 mRNA

NCBI chr 5:170,804,511...170,807,988
Ensembl chr 5:170,803,940...170,806,021

G

hes-related family bHLH transcription factor with YRPW motif 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HEY1 mRNA

NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624

G

heparan-alpha-glucosaminide N-acetyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HGSNAT mRNA

NCBI chr16:72,807,967...72,840,180
Ensembl chr16:72,807,849...72,840,176

G

Hedgehog-interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HHIP mRNA

NCBI chr19:44,768,038...44,856,878
Ensembl chr19:44,767,536...44,862,795

G

3-hydroxyisobutyrate dehydrogenase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HIBADH mRNA

NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:82,979,765...83,111,242

G

hypoxia inducible factor 1 subunit alpha

decreases expression
increases activity
multiple interactions

ISO

Asbestos, Crocidolite results in decreased expression of HIF1A mRNA
Asbestos, Crocidolite results in increased activity of HIF1A protein
ferric nitrilotriacetate inhibits the reaction [Asbestos, Crocidolite results in increased activity of HIF1A protein]

PMID:18385176 PMID:29279043

NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323

G

HIG1 hypoxia inducible domain family, member 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HIGD1A mRNA

NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:130,391,661...130,400,888

G

heat shock protein nuclear import factor hikeshi

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HIKESHI mRNA

NCBI chr 1:153,237,948...153,261,856
Ensembl chr 1:153,237,948...153,261,911

G

homeodomain interacting protein kinase 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of HIPK3 mRNA

NCBI chr 3:111,251,863...111,322,815
Ensembl chr 3:111,251,863...111,322,772

G

HIVEP zinc finger 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of HIVEP1 mRNA
Asbestos, Crocidolite affects the expression of HIVEP1 mRNA

PMID:18687144 PMID:25757056

NCBI chr17:22,790,855...22,920,359
Ensembl chr17:22,790,855...22,917,196

G

HIVEP zinc finger 2

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of HIVEP2 mRNA
Asbestos, Crocidolite affects the expression of HIVEP2 mRNA

PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr 1:10,176,880...10,376,089
Ensembl chr 1:10,179,402...10,376,089

G

HIVEP zinc finger 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HIVEP3 mRNA

NCBI chr 5:138,610,592...139,013,058
Ensembl chr 5:138,943,312...139,010,430

G

hexokinase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HK1 mRNA

NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,773,220...30,874,814

G

hexokinase domain containing 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of HKDC1 mRNA

NCBI chr20:30,878,037...30,917,044
Ensembl chr20:30,878,319...30,916,704

G

HLF transcription factor, PAR bZIP family member

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HLF mRNA

NCBI chr10:75,651,320...75,708,979
Ensembl chr10:75,654,534...75,708,619

G

H2.0-like homeobox

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HLX promoter

NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264

G

homeobox containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HMBOX1 mRNA

NCBI chr15:43,243,503...43,376,011
Ensembl chr15:43,222,470...43,376,011

G

high mobility group AT-hook 1

affects expression
increases expression

ISO
EXP

Asbestos, Crocidolite affects the expression of HMGA1 mRNA
Asbestos, Crocidolite results in increased expression of HMGA1 mRNA

PMID:12839939 PMID:17331233

NCBI chr20:5,612,902...5,620,596
Ensembl chr20:5,613,471...5,620,593

G

high mobility group AT-hook 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HMGA2 mRNA

NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:57,765,675...57,880,341

G

high mobility group box 1

increases expression
decreases expression
increases secretion
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of HMGB1 mRNA
Asbestos, Crocidolite results in decreased expression of HMGB1 mRNA
Asbestos, Crocidolite results in increased secretion of HMGB1 protein
Asbestos, Crocidolite affects the localization of and results in increased secretion of HMGB1 protein; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of HMGB1 protein]; NLRP3 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of HMGB1 protein]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of HMGB1 protein]
Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of HMGB1 protein]

PMID:20616036 PMID:23937860 PMID:24160326 PMID:26678224 PMID:29279043

NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327

G

high mobility group box 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HMGB2 mRNA

NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases activity
increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in decreased activity of HMGCR protein
Asbestos, Crocidolite results in increased expression of HMGCR mRNA
manganese protoporphyrin inhibits the reaction [Asbestos, Crocidolite results in decreased activity of HMGCR protein]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased activity of HMGCR protein]

PMID:21257924 PMID:29279043

NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HMGCS1 mRNA

NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:53,382,643...53,399,802

G

heme oxygenase 1

increases expression
multiple interactions

ISO
EXP

Asbestos, Crocidolite results in increased expression of HMOX1 mRNA; Asbestos, Crocidolite results in increased expression of HMOX1 protein
secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of HMOX1 mRNA]; secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of HMOX1 protein]

PMID:7743507 PMID:8118652 PMID:15814490 PMID:17365036 PMID:18687144 More...

NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818

G

histamine N-methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HNMT mRNA

NCBI chr 3:26,978,274...27,010,291
Ensembl chr 3:26,977,933...27,010,482

G

heterogeneous nuclear ribonucleoprotein A1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of HNRNPA1 mRNA
Asbestos, Crocidolite results in decreased expression of HNRNPA1 mRNA

PMID:19446018 PMID:29279043

NCBI chr 7:136,253,633...136,260,085
Ensembl chr 7:136,253,278...136,260,085

G

heterogeneous nuclear ribonucleoprotein A/B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HNRNPAB mRNA

NCBI chr10:36,358,004...36,363,898
Ensembl chr10:36,358,006...36,364,307

G

heterogeneous nuclear ribonucleoprotein C

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of HNRNPC mRNA
Asbestos, Crocidolite results in decreased expression of HNRNPC mRNA

PMID:29279043 PMID:29523930

NCBI chr15:27,253,098...27,282,779
Ensembl chr15:27,253,098...27,282,715

G

heterogeneous nuclear ribonucleoprotein D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HNRNPD mRNA

NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,919,739...9,938,066

G

heterogeneous nuclear ribonucleoprotein U

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HNRNPU mRNA

NCBI chr13:92,609,791...92,618,580
Ensembl chr13:92,605,216...92,618,612

G

homer scaffold protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HOMER1 mRNA

NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657

G

homeobox A10

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA10 promoter

NCBI chr 4:82,662,204...82,671,490
Ensembl chr 4:82,662,204...82,665,922

G

homeobox A11

decreases expression
decreases methylation

ISO

Asbestos, Crocidolite results in decreased expression of HOXA11 mRNA
Asbestos, Crocidolite results in decreased methylation of HOXA11 promoter

PMID:19446018 PMID:29626692

NCBI chr 4:82,673,139...82,676,801
Ensembl chr 4:82,673,140...82,676,844

G

HOXA11 antisense RNA

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HOXA11OS mRNA

NCBI chr 4:82,677,028...82,680,802
Ensembl chr 4:82,677,028...82,680,791

G

homeo box A13

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA13 promoter

NCBI chr 4:82,689,566...82,691,701
Ensembl chr 4:82,689,566...82,691,701

G

homeobox A3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA3 promoter

NCBI chr 4:82,599,860...82,643,831
Ensembl chr 4:82,599,860...82,643,831

G

homeo box A4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA4 promoter

NCBI chr 4:82,620,294...82,622,302
Ensembl chr 4:82,620,299...82,622,302

G

homeobox A6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA6 promoter

NCBI chr 4:82,637,024...82,639,463

G

homeobox A7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HOXA7 mRNA

NCBI chr 4:82,646,342...82,652,449
Ensembl chr 4:82,646,364...82,648,241

G

homeobox A9

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXA9 promoter

NCBI chr 4:82,653,847...82,659,958
Ensembl chr 4:82,653,825...82,662,093

G

homeo box B1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB1 promoter

NCBI chr10:81,827,915...81,830,404
Ensembl chr10:81,827,915...81,830,404

G

homeo box B3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB3 promoter

NCBI chr10:81,786,001...81,810,655
Ensembl chr10:81,795,882...81,809,628

G

homeo box B5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB5 promoter

NCBI chr10:81,765,911...81,768,119

G

homeo box B6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB6 promoter

NCBI chr10:81,755,263...81,763,999

G

homeo box B7

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB7 promoter

NCBI chr10:81,749,159...81,752,577
Ensembl chr10:81,749,097...81,752,550

G

homeo box B8

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB8 promoter

NCBI chr10:81,745,430...81,747,181
Ensembl chr10:81,739,704...81,747,802

G

homeo box B9

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXB9 promoter

NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872

G

homeobox C11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXC11 promoter

NCBI chr 7:135,969,707...135,973,222
Ensembl chr 7:135,969,989...135,973,222

G

homeo box C4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXC4 promoter

NCBI chr 7:136,049,059...136,051,601
Ensembl chr 7:136,049,059...136,051,601

G

homeo box C5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXC5 promoter

NCBI chr 7:136,029,454...136,032,876
Ensembl chr 7:136,029,454...136,032,876

G

homeobox D11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXD11 promoter

NCBI chr 3:79,992,394...79,994,688
Ensembl chr 3:79,992,394...79,994,688

G

homeo box D12

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXD12 promoter

NCBI chr 3:79,985,106...79,986,227
Ensembl chr 3:79,985,106...79,986,227

G

homeo box D4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXD4 promoter

NCBI chr 3:80,021,886...80,041,462
Ensembl chr 3:80,036,900...80,038,948

G

homeobox D8

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HOXD8 promoter

NCBI chr 3:80,015,223...80,017,789
Ensembl chr 3:80,014,735...80,018,765

G

haptoglobin

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of HP mRNA
Asbestos, Crocidolite results in increased expression of HP mRNA

PMID:23917077 PMID:24160326

NCBI chr19:54,449,151...54,453,701
Ensembl chr19:54,446,217...54,467,518

G

histone PARylation factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HPF1 mRNA

NCBI chr16:34,211,971...34,230,551
Ensembl chr16:34,193,421...34,253,210

G

15-hydroxyprostaglandin dehydrogenase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HPGD mRNA

NCBI chr16:38,996,876...39,034,831
Ensembl chr16:38,996,876...39,034,831

G

HRas proto-oncogene, GTPase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HRAS protein
Asbestos, Crocidolite results in decreased expression of HRAS mRNA

PMID:21570478 PMID:29279043

NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590

G

histamine receptor H 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HRH1 mRNA

NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:149,120,039...149,208,248

G

harakiri, BCL2 interacting protein

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of HRK mRNA
Asbestos, Crocidolite affects the expression of HRK mRNA

PMID:17331233 PMID:29523930

NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561

G

heparan sulfate-glucosamine 3-sulfotransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HS3ST1 mRNA

NCBI chr14:75,398,101...75,429,628
Ensembl chr14:75,398,026...75,436,848

G

heparan sulfate-glucosamine 3-sulfotransferase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HS3ST2 mRNA

NCBI chr 1:185,387,445...185,508,700
Ensembl chr 1:185,386,761...185,508,700

G

hydroxysteroid 11-beta dehydrogenase 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of HSD11B1 mRNA
Asbestos, Crocidolite results in decreased expression of HSD11B1 mRNA

PMID:25351596 PMID:29279043

NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432

G

hydroxysteroid (17-beta) dehydrogenase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSD17B2 mRNA

NCBI chr19:62,662,320...62,733,944
Ensembl chr19:62,662,098...62,733,943

G

hydroxysteroid (17-beta) dehydrogenase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HSD17B4 mRNA

NCBI chr18:45,515,427...45,604,467
Ensembl chr18:45,515,373...45,604,467

G

hydroxysteroid (17-beta) dehydrogenase 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HSD17B7 mRNA

NCBI chr13:84,702,875...84,722,810
Ensembl chr13:84,705,631...84,722,754

G

hydroxysteroid dehydrogenase like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HSDL1 mRNA

NCBI chr19:64,524,435...64,540,527
Ensembl chr19:64,525,891...64,540,762

G

heat shock transcription factor 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of HSF4 promoter

NCBI chr19:50,057,331...50,068,134
Ensembl chr19:50,057,672...50,063,404

G

heat shock protein 90 alpha family class A member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSP90AA1 mRNA

NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499

G

heat shock protein family A (Hsp70) member 12A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HSPA12A mRNA

NCBI chr 1:267,921,780...268,083,171
Ensembl chr 1:267,921,782...268,082,794

G

heat shock protein family A (Hsp70) member 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPA1A mRNA

PMID:18687144 PMID:25351596

NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 1B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPA1B mRNA

NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,855,780...3,877,979

G

heat shock protein family A (Hsp70) member 5

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of HSPA5 protein
OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of HSPA5 protein]

NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790

G

heat shock protein family A (Hsp70) member 6 like, pseudogene 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPA6 mRNA

PMID:18687144 PMID:25351596

NCBI chr13:85,805,911...85,807,052

G

heat shock protein family A (Hsp70) member 8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPA8 protein

NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:50,080,199...50,084,372

G

heat shock protein family B (small) member 8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPB8 mRNA

PMID:18687144 PMID:25351596

NCBI chr12:45,835,899...45,866,449
Ensembl chr12:45,837,066...45,851,937

G

heat shock protein family E (Hsp10) member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HSPE1 mRNA

NCBI chr 9:64,084,327...64,087,415
Ensembl chr 9:64,085,068...64,087,502

G

heat shock protein family H (Hsp110) member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HSPH1 mRNA

NCBI chr12:10,427,368...10,446,602
Ensembl chr12:10,427,297...10,446,891

G

5-hydroxytryptamine receptor 5A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HTR5A mRNA

NCBI chr 4:8,178,802...8,188,485
Ensembl chr 4:8,178,802...8,200,482

G

HtrA serine peptidase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HTRA2 mRNA

NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:117,114,633...117,117,793

G

huntingtin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HTT mRNA

NCBI chr14:80,070,456...80,219,668
Ensembl chr14:80,070,456...80,219,668

G

HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HUWE1 mRNA

NCBI chr X:24,350,708...24,480,798
Ensembl chr X:24,353,217...24,480,798

G

hydrogen voltage-gated channel 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HVCN1 mRNA

NCBI chr12:40,001,205...40,030,671
Ensembl chr12:40,001,498...40,042,020

G

hyccin PI4KA lipid kinase complex subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HYCC2 mRNA

NCBI chr 9:67,551,064...67,623,353
Ensembl chr 9:67,551,064...67,587,186

G

hydroxylysine kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HYKK mRNA

PMID:29279043 PMID:29523930

NCBI chr 8:64,212,043...64,235,809
Ensembl chr 8:64,212,071...64,235,818

G

Huntingtin interacting protein K

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of HYPK mRNA

NCBI chr 3:128,888,709...128,890,089
Ensembl chr 3:128,888,717...128,891,405

G

islet cell autoantigen 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ICA1 mRNA

NCBI chr 4:37,622,759...37,771,055
Ensembl chr 4:37,622,759...37,770,569

G

intercellular adhesion molecule 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of ICAM1 mRNA
Asbestos, Crocidolite affects the expression of ICAM1 mRNA

PMID:25351596 PMID:25757056 PMID:38605572

NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617

G

intercellular adhesion molecule 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ICAM2 mRNA

NCBI chr10:91,808,449...91,819,319
Ensembl chr10:91,808,316...91,815,072

G

inhibitor of DNA binding 1

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of ID1 mRNA
Asbestos, Crocidolite results in increased expression of ID1 mRNA
Asbestos, Crocidolite results in decreased expression of ID1 protein

PMID:17975199 PMID:19446018 PMID:25757056

NCBI chr 3:161,671,525...161,672,691
Ensembl chr 3:161,671,538...161,672,685

G

immediate early response 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IER2 mRNA

NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708

G

immediate early response 3

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of IER3 mRNA
Asbestos, Crocidolite results in increased expression of IER3 mRNA

PMID:18687144 PMID:29279043

NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,933,174...2,934,377

G

interferon-induced protein 44-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFI44L mRNA

NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:243,328,723...243,366,404

G

interferon-induced protein with tetratricopeptide repeats 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFIT2 mRNA

NCBI chr 1:241,515,735...241,521,799
Ensembl chr 1:241,515,709...241,521,798

G

interferon induced transmembrane protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFITM1 mRNA

NCBI chr 1:205,496,757...205,498,796
Ensembl chr 1:205,496,807...205,498,776

G

interferon gamma

multiple interactions
increases expression

ISO

[Asbestos, Crocidolite results in decreased susceptibility to Asbestos, Crocidolite] which results in decreased expression of IFNG protein
[IFNG protein co-treated with Asbestos, Crocidolite] results in increased expression of NOS2 mRNA
Asbestos, Crocidolite results in increased expression of IFNG protein

PMID:9586808 PMID:22608188 PMID:29507420 PMID:29553831

NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216

G

interferon gamma receptor 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of IFNGR2 mRNA

NCBI chr11:44,265,703...44,283,975
Ensembl chr11:44,265,703...44,283,975

G

interferon-related developmental regulator 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IFRD1 mRNA

NCBI chr 6:62,996,560...63,044,996
Ensembl chr 6:62,996,562...63,016,131

G

interferon-related developmental regulator 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IFRD2 mRNA

NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836

G

intraflagellar transport 43

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFT43 mRNA

NCBI chr 6:111,460,689...111,537,224
Ensembl chr 6:111,456,476...111,537,224

G

intraflagellar transport 70A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFT70A1 mRNA

NCBI chr 3:81,309,158...81,312,612

G

intraflagellar transport 88

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IFT88 mRNA

NCBI chr15:35,685,678...35,786,875
Ensembl chr15:35,688,927...35,781,634

G

insulin-like growth factor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of IGF1 mRNA

NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764

G

insulin-like growth factor 1 receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IGF1R mRNA

NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664

G

insulin-like growth factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IGF2 mRNA

NCBI chr 1:207,243,873...207,261,263
Ensembl chr 1:207,243,873...207,260,667

G

insulin-like growth factor binding protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IGFBP2 mRNA

NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171

G

insulin-like growth factor binding protein 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IGFBP5 mRNA

NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:81,897,616...81,914,390

G

insulin-like growth factor binding protein 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IGFBP7 protein

NCBI chr14:31,091,681...31,151,623
Ensembl chr14:31,091,347...31,151,620

G

immunoglobulin lambda-like polypeptide 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IGLL5 protein

NCBI chr11:97,643,059...97,646,441
Ensembl chr11:97,643,187...97,646,438

G

IKAROS family zinc finger 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IKZF5 mRNA

NCBI chr 1:195,599,287...195,619,024
Ensembl chr 1:195,600,967...195,619,013

G

interleukin 10

affects expression
increases expression
decreases expression
multiple interactions

ISO

Asbestos, Crocidolite affects the expression of IL10 mRNA
Asbestos, Crocidolite results in increased expression of IL10 protein
Asbestos, Crocidolite results in decreased expression of IL10 mRNA
[Asbestos, Crocidolite results in decreased susceptibility to Asbestos, Crocidolite] which results in increased expression of IL10 protein

PMID:17331233 PMID:22608188 PMID:29507420 PMID:29523930

NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580

G

interleukin 11

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL11 mRNA

NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:78,096,930...78,104,915

G

interleukin 12A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IL12A mRNA

NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997

G

interleukin 12B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL12B protein

NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194

G

interleukin 13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL13 protein

NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483

G

interleukin 13 receptor subunit alpha 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL13RA2 mRNA

NCBI chr X:115,814,620...115,886,080
Ensembl chr X:115,814,622...115,841,455

G

interleukin 17 receptor D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IL17RD mRNA

NCBI chr16:2,235,172...2,489,827
Ensembl chr16:2,235,169...2,301,850

G

interleukin 18

decreases expression
increases secretion
multiple interactions
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of IL18 mRNA
Asbestos, Crocidolite results in increased secretion of IL18 protein
CASP1 protein affects the reaction [Asbestos, Crocidolite results in increased expression of IL18 protein]
IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL18 protein]

PMID:23937860 PMID:24160326 PMID:28056339 PMID:29523930

NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286

G

interleukin 19

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL19 mRNA

NCBI chr13:44,949,989...44,958,714
Ensembl chr13:44,949,989...44,958,714

G

interleukin 1 alpha

multiple interactions
increases expression

EXP
ISO

[Asbestos, Crocidolite co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1A mRNA]
Asbestos, Crocidolite results in increased expression of IL1A protein

PMID:7539275 PMID:9400719 PMID:24160326 PMID:25757056 PMID:29279043

NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013

G

interleukin 1 beta

affects expression
increases secretion
increases expression
multiple interactions

ISO
EXP

Asbestos, Crocidolite affects the expression of IL1B protein
Asbestos, Crocidolite results in increased secretion of IL1B protein
Asbestos, Crocidolite results in increased expression of IL1B mRNA; Asbestos, Crocidolite results in increased expression of IL1B protein
[Asbestos, Crocidolite co-treated with IL1B protein] results in increased abundance of 3-nitrotyrosine; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased abundance of Nitrates; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 protein; acetovanillone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL1B protein]; Asbestos, Crocidolite results in increased expression of and results in increased secretion of IL1B protein; CASP1 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Cytochalasin B inhibits the reaction [Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; diphenyleneiodonium inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1B mRNA]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; latrunculin A inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; pimagedine inhibits the reaction [Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; Potassium Chloride inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; ROCK1 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; ROCK2 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Y 27632 inhibits the reaction [Asbestos, Crocidolite results in increased expression of and results in increased secretion of IL1B protein]
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; CYBA protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; TXN protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Asbestos, Crocidolite promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]; IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CCL2 mRNA]; IL1B protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CCL2 protein]

PMID:8473757 PMID:9698594 PMID:10444523 PMID:10923243 PMID:18403674 More...

NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601

G

interleukin 1 receptor accessory protein

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of IL1RAP mRNA
Asbestos, Crocidolite results in decreased expression of IL1RAP mRNA

PMID:19446018 PMID:29279043 PMID:29523930

NCBI chr11:87,567,813...87,704,346
Ensembl chr11:87,575,116...87,704,342

G

interleukin 1 receptor-like 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of IL1RL1 mRNA
Asbestos, Crocidolite results in increased expression of IL1RL1 mRNA

PMID:25351596 PMID:25757056

NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891

G

interleukin 1 receptor antagonist

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of IL1RN mRNA
[TNF protein co-treated with Asbestos, Crocidolite] results in increased secretion of IL1RN protein; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL18 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein]; IL1RN protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of FGF2 protein]

PMID:23937860 PMID:24160326 PMID:25351596 PMID:28056339

NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732

G

interleukin 24

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL24 mRNA

PMID:18687144 PMID:24160326 PMID:25351596

NCBI chr13:44,905,362...44,910,760
Ensembl chr13:44,905,363...44,910,760

G

interleukin 31 receptor A

affects expression

ISO

Asbestos, Crocidolite affects the expression of IL31RA mRNA

NCBI chr 2:45,851,073...45,922,300
Ensembl chr 2:45,855,868...45,917,009

G

interleukin 33

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL33 mRNA

NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901

G

interleukin 36, gamma

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL36G mRNA

NCBI chr 3:27,346,675...27,352,839
Ensembl chr 3:27,346,670...27,352,834

G

interleukin 36 receptor antagonist

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL36RN mRNA

NCBI chr 3:27,442,679...27,449,306
Ensembl chr 3:27,442,709...27,449,306

G

interleukin 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL4 protein

NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549

G

interleukin 4 induced 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of IL4I1 mRNA

NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:104,435,981...104,461,053

G

interleukin 4 receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL4R mRNA

NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:189,544,988...189,570,636

G

interleukin 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL5 protein

PMID:26119930 PMID:29279043

NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003

G

interleukin 6

multiple interactions
increases expression
increases secretion
affects expression

ISO

1,2-Dipalmitoylphosphatidylcholine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; 1,3-dimethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL6 protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 mRNA]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; prolinedithiocarbamate inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [CEBPB protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]
Asbestos, Crocidolite results in increased expression of IL6 mRNA; Asbestos, Crocidolite results in increased expression of IL6 protein
Asbestos, Crocidolite affects the expression of IL6 protein
Asbestos, Crocidolite affects the expression of IL6 mRNA
Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 protein]; MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 mRNA]

PMID:9378980 PMID:10022265 PMID:11250057 PMID:18192500 PMID:18687144 More...

NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610

G

interleukin 6 receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IL6R mRNA

NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221

G

interleukin 7 receptor

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of IL7R mRNA
Asbestos, Crocidolite results in decreased expression of IL7R mRNA

PMID:24160326 PMID:29279043

NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027

G

interleukin enhancer binding factor 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of ILF3 mRNA

NCBI chr 8:28,198,454...28,236,634
Ensembl chr 8:28,198,543...28,236,612

G

integrin-linked kinase

increases expression

EXP

Asbestos, Crocidolite results in increased expression of ILK mRNA

NCBI chr 1:169,500,716...169,506,972
Ensembl chr 1:169,498,681...169,506,964

G

ILK associated serine/threonine phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ILKAP mRNA

NCBI chr 9:99,413,981...99,436,262
Ensembl chr 9:99,413,978...99,436,418

G

ilvB acetolactate synthase like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of HACL2 mRNA

NCBI chr 7:11,690,445...11,700,498
Ensembl chr 7:11,690,445...11,700,498

G

inositol monophosphatase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IMPA2 mRNA

NCBI chr18:63,104,113...63,135,232
Ensembl chr18:63,104,083...63,137,543

G

inosine monophosphate dehydrogenase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IMPDH2 mRNA

NCBI chr 8:118,135,204...118,139,892
Ensembl chr 8:118,135,262...118,139,873

G

inverted formin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of INF2 mRNA

NCBI chr 6:137,470,259...137,497,039
Ensembl chr 6:137,470,286...137,497,039

G

inhibitor of growth family, member 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ING1 mRNA
Asbestos, Crocidolite results in decreased expression of ING1 mRNA

PMID:18687144 PMID:29279043

NCBI chr16:84,639,378...84,649,498
Ensembl chr16:84,639,381...84,647,616

G

inhibin subunit beta A

affects expression
increases expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of INHBA mRNA
Asbestos, Crocidolite results in increased expression of INHBA mRNA
Asbestos, Crocidolite results in decreased expression of INHBA protein

PMID:23634900 PMID:24160326 PMID:25351596 PMID:25757056 PMID:29279043

NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508

G

INTS3 and NABP interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INIP mRNA

NCBI chr 5:79,443,317...79,457,552
Ensembl chr 5:79,443,317...79,457,552

G

indolethylamine N-methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INMT mRNA

NCBI chr 4:85,648,459...85,652,755
Ensembl chr 4:85,648,459...85,652,755

G

inositol polyphosphate-4-phosphatase type II B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of INPP4B mRNA

NCBI chr19:42,824,710...43,575,039
Ensembl chr19:42,829,871...43,185,091

G

inositol polyphosphate-5-phosphatase B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INPP5B mRNA

NCBI chr 5:142,281,454...142,345,993
Ensembl chr 5:142,281,418...142,345,991

G

inositol polyphosphate-5-phosphatase D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INPP5D mRNA

NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589

G

inositol polyphosphate phosphatase-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INPPL1 mRNA

NCBI chr 1:165,595,047...165,609,503
Ensembl chr 1:165,595,063...165,609,503

G

insulin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of INS-IGF2 protein

NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682

G

integrator complex subunit 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INTS12 mRNA

NCBI chr 2:224,265,787...224,283,523
Ensembl chr 2:224,265,736...224,283,516

G

integrator complex subunit 6

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of INTS6 mRNA
Asbestos, Crocidolite results in decreased expression of INTS6 mRNA

PMID:18687144 PMID:29279043

NCBI chr15:41,080,584...41,224,350
Ensembl chr15:41,109,125...41,197,519

G

integrator complex subunit 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INTS7 mRNA

NCBI chr13:105,686,208...105,739,609
Ensembl chr13:105,686,128...105,739,608

G

integrator complex subunit 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of INTS8 mRNA

NCBI chr 5:29,094,475...29,141,874
Ensembl chr 5:29,094,475...29,142,099

G

inositol hexakisphosphate kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IP6K2 mRNA

NCBI chr 8:118,362,154...118,388,668
Ensembl chr 8:118,362,795...118,388,667

G

interaction protein for cytohesin exchange factors 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IPCEF1 mRNA

NCBI chr 1:45,654,252...45,857,045
Ensembl chr 1:45,662,818...45,856,993

G

IQ motif containing E

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IQCE mRNA

NCBI chr12:19,057,060...19,096,626
Ensembl chr12:19,056,307...19,096,624

G

IQ motif containing GTPase activating protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of IQGAP1 mRNA

NCBI chr 1:144,088,788...144,178,989
Ensembl chr 1:144,088,793...144,179,043

G

IQ motif containing GTPase activating protein 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of IQGAP2 mRNA

NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649

G

IQ motif containing GTPase activating protein 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of IQGAP3 mRNA

NCBI chr 2:175,840,001...175,881,799
Ensembl chr 2:175,839,949...175,881,797

G

inositol 1,4,5-triphosphate receptor associated 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IRAG1 mRNA

NCBI chr 1:174,416,383...174,528,913
Ensembl chr 1:174,416,385...174,528,851

G

interleukin-1 receptor-associated kinase 1 binding protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IRAK1BP1 mRNA

NCBI chr 8:92,608,468...92,628,377
Ensembl chr 8:92,611,843...92,628,377

G

interleukin-1 receptor-associated kinase 2

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of IRAK2 mRNA
Asbestos, Crocidolite results in decreased expression of IRAK2 mRNA
Asbestos, Crocidolite affects the expression of IRAK2 mRNA

PMID:18687144 PMID:24160326 PMID:25757056 PMID:29279043

NCBI chr 4:148,341,704...148,398,211
Ensembl chr 4:148,341,719...148,398,210

G

interleukin-1 receptor-associated kinase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IRAK3 mRNA

NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:57,539,557...57,598,706

G

interferon regulatory factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IRF1 mRNA

NCBI chr10:38,417,935...38,424,946
Ensembl chr10:38,417,148...38,424,947

G

interferon regulatory factor 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IRF5 mRNA

NCBI chr 4:59,092,914...59,104,596
Ensembl chr 4:59,081,357...59,112,552

G

interferon regulatory factor 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IRF8 mRNA

NCBI chr19:65,699,284...65,721,066
Ensembl chr19:65,699,284...65,721,062

G

insulin receptor substrate 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IRS2 mRNA

NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543

G

iroquois homeobox 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IRX5 mRNA

NCBI chr19:30,812,033...30,816,885
Ensembl chr19:30,797,202...30,815,029

G

iroquois homeobox 6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of IRX6 promoter

NCBI chr19:30,503,416...30,509,396
Ensembl chr19:30,503,419...30,509,382

G

interferon stimulated exonuclease gene 20

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ISG20 mRNA

NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401

G

ISL LIM homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ISL2 promoter

NCBI chr 8:64,819,879...64,824,864
Ensembl chr 8:64,819,879...64,824,864

G

itchy E3 ubiquitin protein ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ITCH mRNA

NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:164,105,812...164,193,932

G

integrin subunit alpha 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ITGA1 mRNA

NCBI chr 2:48,379,181...48,545,336
Ensembl chr 2:48,386,249...48,545,284

G

integrin subunit beta 1

multiple interactions
decreases expression

EXP
ISO

ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of AKT1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
Asbestos, Crocidolite results in decreased expression of ITGB1 mRNA

PMID:14627993 PMID:29279043

NCBI chr19:73,602,277...73,650,271
Ensembl chr19:73,602,126...73,650,269

G

integrin subunit beta 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ITGB2 mRNA

NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,058,492...11,097,182

G

inter-alpha-trypsin inhibitor heavy chain 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ITIH4 protein

NCBI chr16:6,086,985...6,102,162
Ensembl chr16:6,086,973...6,102,160

G

intelectin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ITLN1 mRNA

NCBI chr13:86,464,641...86,490,655
Ensembl chr13:86,464,669...86,490,651

G

inositol 1,4,5-trisphosphate receptor interacting protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of ITPRIP mRNA

PMID:24160326 PMID:25757056

NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:256,699,832...256,727,644

G

ITPRIP like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of ITPRIPL1 mRNA

NCBI chr 3:134,858,316...134,861,241
Ensembl chr 3:134,854,417...134,868,960

G

intersectin 1

multiple interactions
decreases expression
increases expression

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of ITSN1 mRNA]
Asbestos, Crocidolite results in decreased expression of ITSN1 mRNA
Asbestos, Crocidolite results in increased expression of ITSN1 mRNA

PMID:19446018 PMID:29523930

NCBI chr11:44,464,515...44,646,598
Ensembl chr11:44,513,186...44,646,598

G

intersectin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ITSN2 mRNA

NCBI chr 6:33,336,086...33,446,818
Ensembl chr 6:33,336,441...33,446,818

G

involucrin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of IVL mRNA

NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:180,842,307...180,846,578

G

influenza virus NS1A binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IVNS1ABP mRNA

NCBI chr13:65,977,069...65,996,685
Ensembl chr13:65,977,045...65,997,547

G

IZUMO family member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of IZUMO3 mRNA

NCBI chr 5:111,990,148...111,992,826
Ensembl chr 5:111,989,359...111,992,785

G

jade family PHD finger 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of JADE1 mRNA

NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:126,471,124...126,524,252

G

jagged canonical Notch ligand 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of JAG1 mRNA

NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:144,859,453...144,894,872

G

jagged canonical Notch ligand 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of JAG2 mRNA

NCBI chr 6:137,804,133...137,826,738
Ensembl chr 6:137,804,133...137,826,738

G

jumonji domain containing 1C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of JMJD1C mRNA

NCBI chr20:21,330,990...21,508,580
Ensembl chr20:21,330,990...21,461,916

G

jumonji domain containing 6, arginine demethylase and lysine hydroxylase

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of JMJD6 mRNA
Asbestos, Crocidolite results in decreased expression of JMJD6 mRNA

PMID:25351596 PMID:29279043

NCBI chr10:102,539,935...102,545,986
Ensembl chr10:102,539,894...102,545,986

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression
affects expression
decreases phosphorylation

EXP
ISO

Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; calphostin C inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; [GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; AG 1879 inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; EGFR protein promotes the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; MAPK7 protein affects the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]
Asbestos, Crocidolite affects the expression of JUN protein modified form
Asbestos, Crocidolite results in decreased phosphorylation of JUN protein
Asbestos, Crocidolite results in increased expression of JUN; Asbestos, Crocidolite results in increased expression of JUN mRNA; Asbestos, Crocidolite results in increased expression of JUN protein

PMID:7743507 PMID:8025751 PMID:8386370 PMID:8679218 PMID:9242432 More...

NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of JUNB mRNA
[GCLC protein co-treated with GCLM protein] inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]; Buthionine Sulfoximine promotes the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]; GCLM protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]; Glutathione inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]

PMID:15520183 PMID:18687144

NCBI chr19:40,081,126...40,082,910
Ensembl chr19:40,073,541...40,085,218

G

KN motif and ankyrin repeat domains 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KANK4 mRNA

NCBI chr 5:118,516,994...118,581,024
Ensembl chr 5:118,517,971...118,581,002

G

KAT8 regulatory NSL complex subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KANSL2 mRNA

NCBI chr 7:131,548,062...131,564,876
Ensembl chr 7:131,548,062...131,564,753

G

lysine acetyltransferase 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KAT14 mRNA

NCBI chr 3:152,194,560...152,235,048
Ensembl chr 3:152,194,696...152,235,052

G

lysine acetyltransferase 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of KAT5 mRNA

NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587

G

lysine acetyltransferase 6A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KAT6A mRNA

NCBI chr16:75,787,411...75,868,584
Ensembl chr16:75,787,411...75,866,099

G

katanin catalytic subunit A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KATNA1 mRNA

NCBI chr 1:4,022,886...4,064,513
Ensembl chr 1:4,022,876...4,064,512

G

katanin regulatory subunit B1 like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KATNBL1 mRNA

NCBI chr 3:119,638,068...119,680,179
Ensembl chr 3:119,638,107...119,680,173

G

kelch repeat and BTB domain containing 11

multiple interactions
increases expression

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of KBTBD11 mRNA]
Asbestos, Crocidolite results in increased expression of KBTBD11 mRNA

NCBI chr16:81,318,596...81,340,334
Ensembl chr16:81,313,093...81,340,390

G

potassium voltage-gated channel subfamily B member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KCNB1 mRNA

NCBI chr 3:176,239,285...176,332,408
Ensembl chr 3:176,242,589...176,332,408

G

potassium inwardly-rectifying channel, subfamily J, member 14

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of KCNJ14 5' UTR

NCBI chr 1:105,429,607...105,437,258
Ensembl chr 1:105,429,883...105,433,892
Ensembl chr 1:105,429,883...105,433,892

G

potassium inwardly-rectifying channel, subfamily J, member 15

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KCNJ15 mRNA

NCBI chr11:48,046,953...48,091,285
Ensembl chr11:48,035,655...48,092,457

G

potassium inwardly-rectifying channel, subfamily J, member 2

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of KCNJ2 mRNA
Asbestos, Crocidolite results in increased expression of KCNJ2 mRNA

PMID:18687144 PMID:29523930

NCBI chr10:96,560,225...96,570,788
Ensembl chr10:96,565,600...96,570,901

G

potassium two pore domain channel subfamily K member 5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of KCNK5 gene

NCBI chr15:4,171,625...4,213,896
Ensembl chr15:4,171,610...4,213,897

G

potassium channel tetramerization domain containing 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KCTD12 mRNA

NCBI chr15:86,214,786...86,220,725
Ensembl chr15:86,214,840...86,224,539

G

potassium channel tetramerization domain containing 18

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KCTD18 mRNA

NCBI chr 9:66,996,440...67,061,069
Ensembl chr 9:66,996,447...67,061,069

G

potassium channel tetramerization domain containing 19

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of KCTD19 gene

NCBI chr19:50,169,814...50,202,121
Ensembl chr19:50,169,891...50,202,103

G

potassium channel tetramerization domain containing 4

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of KCTD4 3' UTR

NCBI chr15:57,675,024...57,686,816
Ensembl chr15:57,673,741...57,687,798

G

KDEL endoplasmic reticulum protein retention receptor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KDELR2 mRNA

NCBI chr12:16,252,424...16,270,737
Ensembl chr12:16,252,424...16,270,719

G

lysine demethylase 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KDM1B mRNA

NCBI chr17:17,809,232...17,850,141
Ensembl chr17:17,809,232...17,850,068

G

lysine demethylase 2B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KDM2B mRNA

NCBI chr12:39,224,422...39,362,126
Ensembl chr12:39,235,301...39,362,127

G

lysine demethylase 3A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KDM3A mRNA

NCBI chr 4:105,189,208...105,233,526
Ensembl chr 4:105,189,208...105,233,370

G

lysine demethylase 4A

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of KDM4A 5' UTR

NCBI chr 5:136,958,178...137,004,942
Ensembl chr 5:136,958,178...137,004,951

G

lysine demethylase 5B

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of KDM5B mRNA
Asbestos, Crocidolite results in decreased expression of KDM5B mRNA

PMID:18687144 PMID:29279043

NCBI chr13:48,554,367...48,625,721
Ensembl chr13:48,554,420...48,626,423

G

lysine demethylase 6A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KDM6A mRNA

NCBI chr X:6,920,374...7,060,027
Ensembl chr X:6,920,343...7,059,960

G

lysine demethylase 6B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KDM6B mRNA

NCBI chr10:54,619,520...54,641,014
Ensembl chr10:54,619,544...54,629,610

G

kinase insert domain receptor

increases secretion

ISO

Asbestos, Crocidolite results in increased secretion of KDR protein

NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192

G

kinase D-interacting substrate 220

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KIDINS220 mRNA

NCBI chr 6:47,346,790...47,435,599
Ensembl chr 6:47,346,832...47,431,865

G

kinesin family member 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KIF12 mRNA

NCBI chr 5:81,611,730...81,620,977
Ensembl chr 5:81,611,734...81,618,369

G

kinesin family member 16B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KIF16B mRNA

NCBI chr 3:150,428,233...150,707,755
Ensembl chr 3:150,366,838...150,707,770

G

kinesin family member 23

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KIF23 mRNA

NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856

G

kinesin family member 3a

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of KIF3A gene

NCBI chr10:38,226,388...38,263,062
Ensembl chr10:38,226,741...38,260,516

G

kinesin family binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KIFBP mRNA

NCBI chr20:31,055,625...31,075,232
Ensembl chr20:31,055,626...31,075,201

G

kinesin family member C1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of KIFC1 5' UTR

NCBI chr20:5,000,929...5,018,967
Ensembl chr20:5,000,648...5,018,988

G

kirre like nephrin family adhesion molecule 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KIRREL3 mRNA

NCBI chr 8:41,123,692...41,663,528
Ensembl chr 8:41,123,878...41,664,147

G

KLF transcription factor 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KLF10 mRNA

NCBI chr 7:71,352,612...71,358,680
Ensembl chr 7:71,350,573...71,358,948

G

KLF transcription factor 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLF12 mRNA

NCBI chr15:83,037,548...83,469,998
Ensembl chr15:83,045,463...83,670,640

G

KLF transcription factor 13

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLF13 mRNA

NCBI chr 1:126,917,671...126,948,436
Ensembl chr 1:126,916,781...126,961,056

G

KLF transcription factor 4

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of KLF4 mRNA
Asbestos, Crocidolite affects the expression of KLF4 mRNA

PMID:18687144 PMID:25757056

NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592

G

KLF transcription factor 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KLF6 mRNA

PMID:18687144 PMID:25351596

NCBI chr17:69,449,483...69,458,478
Ensembl chr17:69,441,493...69,498,601

G

KLF transcription factor 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLF7 mRNA

NCBI chr 9:72,927,485...73,020,167
Ensembl chr 9:72,933,136...73,020,056

G

KLF transcription factor 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLF9 mRNA

NCBI chr 1:230,126,646...230,151,641
Ensembl chr 1:230,126,646...230,151,641

G

kelch-like family member 15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLHL15 mRNA

NCBI chr X:62,987,762...63,043,980
Ensembl chr X:62,989,426...63,039,870

G

kelch-like family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLHL2 mRNA

NCBI chr16:29,627,171...29,739,782
Ensembl chr16:29,627,237...29,739,957

G

kelch-like family member 24

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KLHL24 mRNA

NCBI chr11:94,348,024...94,382,085
Ensembl chr11:94,351,157...94,382,050

G

kelch-like family member 36

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of KLHL36 gene

NCBI chr19:64,830,218...64,851,251
Ensembl chr19:64,836,877...64,851,250

G

kelch-like family, member 42

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of KLHL42 5' UTR

NCBI chr 4:181,730,343...181,760,899
Ensembl chr 4:181,735,244...181,757,013

G

kelch-like family member 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLHL5 mRNA

PMID:29279043 PMID:29523930

NCBI chr14:43,497,915...43,565,833
Ensembl chr14:43,497,918...43,537,894

G

kelch-like family member 9

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of KLHL9 promoter

NCBI chr 5:108,449,492...108,453,676
Ensembl chr 5:108,437,583...108,454,140

G

kallikrein 1

increases activity

ISO

Asbestos, Crocidolite results in increased activity of KLK1 protein

NCBI chr 1:103,779,152...103,783,270
Ensembl chr 1:103,779,164...103,783,270

G

kallikrein related-peptidase 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KLK10 mRNA

NCBI chr 1:103,371,638...103,375,918
Ensembl chr 1:103,371,638...103,375,918

G

killer cell lectin like receptor B1A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLRB1A mRNA

NCBI chr 4:163,576,672...163,590,201
Ensembl chr 4:163,576,672...163,619,374

G

killer cell lectin like receptor D1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KLRD1 mRNA

NCBI chr 4:164,730,833...164,742,539
Ensembl chr 4:164,730,856...164,742,538

G

kynurenine 3-monooxygenase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KMO mRNA

NCBI chr13:90,089,340...90,121,108
Ensembl chr13:90,089,463...90,125,151

G

lysine methyltransferase 2B

affects expression

ISO

Asbestos, Crocidolite affects the expression of KMT2B mRNA

NCBI chr 1:94,949,144...94,969,239
Ensembl chr 1:94,949,144...94,968,441

G

KRIT1, ankyrin repeat containing

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KRIT1 mRNA

NCBI chr 4:31,253,918...31,288,066
Ensembl chr 4:31,253,918...31,288,073

G

keratin 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KRT12 mRNA

NCBI chr10:84,866,965...84,874,265
Ensembl chr10:84,866,965...84,874,265

G

keratin 18

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KRT18 protein

NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:135,035,982...135,039,848
Ensembl chr10:135,035,982...135,039,848

G

keratin 19

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KRT19 mRNA

NCBI chr10:85,576,235...85,580,952
Ensembl chr10:85,576,235...85,580,952

G

keratin 23

increases expression

ISO

Asbestos, Crocidolite results in increased expression of KRT23 mRNA

NCBI chr10:84,930,603...84,946,929
Ensembl chr10:84,930,603...84,946,929

G

keratin 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of KRT7 mRNA

NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786

G

kynureninase

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of KYNU mRNA
Asbestos, Crocidolite results in decreased expression of KYNU mRNA
Asbestos, Crocidolite affects the expression of KYNU mRNA

PMID:24160326 PMID:25351596 PMID:25757056 PMID:29279043

NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014

G

lactamase, beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LACTB mRNA

NCBI chr 8:76,452,679...76,469,986
Ensembl chr 8:76,452,349...76,468,716

G

lactalbumin, alpha

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LALBA mRNA

NCBI chr 7:131,504,572...131,520,707
Ensembl chr 7:131,504,572...131,507,072

G

laminin subunit alpha 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LAMA4 mRNA

NCBI chr20:43,946,898...44,087,972
Ensembl chr20:43,946,898...44,087,972

G

laminin subunit gamma 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of LAMC1 gene

NCBI chr13:67,924,872...68,051,986
Ensembl chr13:67,924,872...68,051,986

G

laminin subunit gamma 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LAMC2 mRNA

NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LAMTOR2 mRNA

NCBI chr 2:176,306,353...176,310,617
Ensembl chr 2:176,306,280...176,310,730

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LAMTOR3 mRNA

NCBI chr 2:229,084,795...229,097,028
Ensembl chr 2:229,084,858...229,099,383

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LAMTOR4 mRNA

NCBI chr12:22,372,269...22,376,090
Ensembl chr12:22,372,269...22,376,090

G

lysosomal protein transmembrane 4 beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LAPTM4B mRNA

NCBI chr 7:67,319,438...67,362,547
Ensembl chr 7:67,319,542...67,363,258

G

La ribonucleoprotein 1B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LARP1B mRNA

PMID:18687144 PMID:29279043

NCBI chr 2:125,860,935...125,897,189
Ensembl chr 2:125,863,997...125,897,189

G

La ribonucleoprotein 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LARP4 mRNA

NCBI chr 7:132,983,276...133,031,514
Ensembl chr 7:132,980,385...133,029,633

G

La ribonucleoprotein 6, translational regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LARP6 mRNA

NCBI chr 8:70,079,753...70,101,175
Ensembl chr 8:70,079,647...70,101,198

G

leucyl-tRNA synthetase 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of LARS1 mRNA
Asbestos, Crocidolite results in decreased expression of LARS1 mRNA

PMID:29279043 PMID:29523930

NCBI chr18:34,452,567...34,507,030
Ensembl chr18:34,452,561...34,506,938

G

linker for activation of T cells

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of LAT mRNA
Asbestos, Crocidolite results in decreased expression of LAT mRNA

PMID:17331233 PMID:29279043

NCBI chr 1:190,367,111...190,372,515
Ensembl chr 1:190,367,109...190,372,153

G

large tumor suppressor kinase 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of LATS2 mRNA
Asbestos, Crocidolite results in decreased expression of LATS2 mRNA

PMID:18687144 PMID:29279043

NCBI chr15:35,940,632...35,992,225
Ensembl chr15:35,940,632...35,980,842

G

lymphocyte transmembrane adaptor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of LAX1 mRNA

NCBI chr13:47,686,840...47,697,396
Ensembl chr13:47,686,849...47,697,460

G

lipopolysaccharide binding protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LBP mRNA

PMID:23917077 PMID:29279043

NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518

G

lamin B receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LBR mRNA

NCBI chr13:96,071,058...96,095,709
Ensembl chr13:96,071,081...96,095,709

G

ladybird homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LBX2 promoter

NCBI chr 4:117,149,690...117,151,575
Ensembl chr 4:117,149,690...117,151,575

G

LCK proto-oncogene, Src family tyrosine kinase

affects expression

ISO

Asbestos, Crocidolite affects the expression of LCK mRNA

NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267

G

leucine carboxyl methyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LCMT1 mRNA

NCBI chr 1:187,335,173...187,391,195
Ensembl chr 1:187,327,706...187,391,516

G

lipocalin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LCN2 mRNA

NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842

G

ligand dependent nuclear receptor corepressor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LCOR mRNA

NCBI chr 1:250,247,965...250,354,985
Ensembl chr 1:250,247,934...250,354,985

G

ligand dependent nuclear receptor corepressor-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LCORL mRNA

NCBI chr14:69,482,919...69,620,269
Ensembl chr14:69,518,837...69,587,177

G

lipid droplet assembly factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LDAF1 mRNA

NCBI chr 1:183,915,919...183,934,374
Ensembl chr 1:183,849,812...183,934,666

G

lipid droplet associated hydrolase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LDAH mRNA

NCBI chr 6:36,801,359...36,885,929
Ensembl chr 6:36,801,359...36,885,923

G

lactate dehydrogenase A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LDHA protein

NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521

G

lactate dehydrogenase B

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LDHB gene

NCBI chr 4:177,159,389...177,177,408
Ensembl chr 4:177,159,392...177,177,408

G

low density lipoprotein receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LDLR mRNA

NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675

G

leptin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LEP mRNA

NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661

G

leptin receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LEPR mRNA

NCBI chr 5:121,409,735...121,593,201
Ensembl chr 5:121,474,099...121,591,215

G

leptin receptor overlapping transcript-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LEPROTL1 mRNA

NCBI chr16:64,744,148...64,756,776
Ensembl chr16:64,743,717...64,756,776

G

leucine zipper and EF-hand containing transmembrane protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LETM2 mRNA

NCBI chr16:73,171,768...73,192,336
Ensembl chr16:73,167,727...73,192,373

G

LETM1 domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LETMD1 mRNA

NCBI chr 7:133,461,920...133,476,592
Ensembl chr 7:133,462,825...133,476,591

G

galectin 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LGALS7 mRNA

NCBI chr 1:93,275,092...93,279,529
Ensembl chr 1:93,273,836...93,279,528

G

lengsin, lens protein with glutamine synthetase domain

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LGSN mRNA

NCBI chr 9:40,912,398...40,943,955
Ensembl chr 9:40,916,520...40,943,943

G

LIM homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LHX2 promoter

NCBI chr 3:42,523,345...42,553,646
Ensembl chr 3:42,535,744...42,553,645

G

LIM homeobox 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LHX3 promoter

NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:29,424,620...29,432,637

G

LIM homeobox 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LHX4 mRNA

NCBI chr13:70,423,768...70,477,337
Ensembl chr13:70,427,399...70,467,505

G

LIM homeobox 6

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LHX6 promoter

NCBI chr 3:39,829,846...39,853,681
Ensembl chr 3:39,830,990...39,853,559

G

LIM homeobox 8

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LHX8 promoter

NCBI chr 2:245,904,712...245,929,376
Ensembl chr 2:245,904,712...245,929,376

G

LIF, interleukin 6 family cytokine

affects expression

ISO

Asbestos, Crocidolite affects the expression of LIF mRNA

NCBI chr14:83,354,602...83,364,053
Ensembl chr14:83,358,164...83,364,053

G

LIF receptor subunit alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LIFR mRNA

NCBI chr 2:57,951,787...58,020,357
Ensembl chr 2:57,952,975...58,020,364

G

DNA ligase 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LIG4 mRNA

NCBI chr16:86,220,345...86,228,930
Ensembl chr16:86,220,279...86,229,926

G

LIM domain and actin binding 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of LIMA1 mRNA
Asbestos, Crocidolite results in decreased expression of LIMA1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 7:132,780,556...132,880,343
Ensembl chr 7:132,780,556...132,880,386

G

LIM and calponin homology domains 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LIMCH1 mRNA

PMID:25351596 PMID:29279043

NCBI chr14:41,466,433...41,779,477
Ensembl chr14:41,466,433...41,778,837

G

Lck interacting transmembrane adaptor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LIME1 mRNA

NCBI chr 3:188,868,338...188,870,661
Ensembl chr 3:188,868,320...188,870,658

G

LIM zinc finger domain containing 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of LIMS1 mRNA

NCBI chr20:26,851,364...26,961,607
Ensembl chr20:26,852,996...26,961,606

G

lin-28 homolog B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LIN28B mRNA

NCBI chr20:50,447,700...50,547,135
Ensembl chr20:50,450,971...50,541,968

G

lin-52 DREAM MuvB core complex component

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LIN52 mRNA

NCBI chr 6:109,829,896...109,927,122
Ensembl chr 6:109,830,131...109,925,310

G

lin-7 homolog A, crumbs cell polarity complex component

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of LIN7A 5' UTR

NCBI chr 7:44,473,568...44,629,074
Ensembl chr 7:44,473,347...44,625,208

G

lipase G, endothelial type

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LIPG mRNA

NCBI chr18:70,790,077...70,811,259
Ensembl chr18:70,790,077...70,812,260

G

LMBR1 domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LMBRD2 mRNA

NCBI chr 2:59,916,736...59,978,739
Ensembl chr 2:59,916,749...59,978,738

G

lamin A/C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LMNA protein

NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:176,237,564...176,288,072

G

lamin tail domain containing 1

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of LMNTD1 5' UTR; Asbestos, Crocidolite affects the methylation of LMNTD1 gene

NCBI chr 4:180,085,128...180,319,362
Ensembl chr 4:180,085,134...180,329,707

G

lamin tail domain containing 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LMNTD2 mRNA

PMID:19446018 PMID:29279043

NCBI chr 1:205,744,694...205,750,460
Ensembl chr 1:205,744,697...205,748,738

G

LIM domain only 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LMO3 mRNA

NCBI chr 4:172,965,944...173,028,980
Ensembl chr 4:172,965,951...173,025,156

G

LIM domain 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LMO7 mRNA

NCBI chr15:84,981,689...85,184,554
Ensembl chr15:84,981,735...85,184,551

G

LIM homeobox transcription factor 1 alpha

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LMX1A promoter

NCBI chr13:82,367,493...82,511,157
Ensembl chr13:82,367,933...82,511,154

G

ligand of numb-protein X 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LNX1 5' UTR

NCBI chr14:33,868,517...33,971,217
Ensembl chr14:33,868,571...33,971,217

G

lysyl oxidase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LOX mRNA

NCBI chr18:48,162,889...48,175,640
Ensembl chr18:48,165,688...48,239,810

G

lysophosphatidic acid receptor 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LPAR6 mRNA

NCBI chr15:54,826,110...54,827,919
Ensembl chr15:54,823,717...54,978,783

G

lysophosphatidylcholine acyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LPCAT1 mRNA

NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:31,594,622...31,644,946

G

lipin 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LPIN1 gene

NCBI chr 6:45,039,110...45,145,845
Ensembl chr 6:45,041,522...45,145,991

G

leucine rich repeats and calponin homology domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRCH2 mRNA

NCBI chr X:115,903,760...115,986,569
Ensembl chr X:115,903,767...115,986,266

G

leucine-rich alpha-2-glycoprotein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LRG1 mRNA

NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337

G

leucine-rich repeats and immunoglobulin-like domains 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRIG1 mRNA

NCBI chr 4:128,687,723...128,788,219
Ensembl chr 4:128,687,723...128,788,219

G

leucine rich repeat containing 36

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of LRRC36 5' UTR

NCBI chr19:50,201,944...50,252,338
Ensembl chr19:50,201,987...50,252,338

G

leucine rich repeat containing 74B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRRC74B mRNA

NCBI chr11:96,954,648...96,974,290
Ensembl chr11:96,954,449...96,974,288

G

leucine rich repeat containing 8 VRAC subunit C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LRRC8C mRNA

NCBI chr14:4,528,721...4,621,259
Ensembl chr14:4,531,823...4,620,049

G

leucine rich repeat containing 8 VRAC subunit D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRRC8D mRNA

NCBI chr14:4,335,114...4,411,549
Ensembl chr14:4,332,130...4,445,639

G

LRR binding FLII interacting protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRRFIP1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 9:99,039,590...99,167,805
Ensembl chr 9:99,039,614...99,167,779

G

leucine-rich repeat kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LRRK2 mRNA

NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:124,706,080...124,867,239

G

leucine rich repeat transmembrane neuronal 3

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of LRRTM3 5' UTR; Asbestos, Crocidolite affects the methylation of LRRTM3 exon

NCBI chr20:24,514,304...24,688,322
Ensembl chr20:24,514,284...24,689,002

G

LSM10, U7 small nuclear RNA associated

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LSM10 mRNA

NCBI chr 5:143,649,817...143,660,391
Ensembl chr 5:143,615,360...143,663,986

G

LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LSM5 mRNA

NCBI chr 4:87,281,260...87,284,476
Ensembl chr 4:87,281,260...87,284,476
Ensembl chr 6:87,281,260...87,284,476

G

leukotriene B4 receptor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LTB4R2 mRNA

NCBI chr15:33,228,634...33,230,453
Ensembl chr15:33,228,634...33,230,453

G

latent transforming growth factor beta binding protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LTBP2 protein

NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298

G

leukocyte receptor tyrosine kinase

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of LTK promoter

NCBI chr 3:127,188,479...127,195,356
Ensembl chr 3:127,188,480...127,197,402

G

LUC7 pre-mRNA splicing factor like 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LUC7L3 mRNA

NCBI chr10:79,737,457...79,773,478
Ensembl chr10:79,736,853...79,773,429

G

leucine rich adaptor protein 1-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LURAP1L mRNA

NCBI chr 5:100,402,921...100,455,479
Ensembl chr 5:100,407,483...100,455,478

G

leucine zipper protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of LUZP1 mRNA

NCBI chr 5:153,989,570...154,065,071
Ensembl chr 5:153,987,683...154,070,438

G

latexin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LXN mRNA

NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488

G

lymphocyte antigen 6 family member G6C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LY6G6C mRNA

NCBI chr20:3,758,290...3,760,987
Ensembl chr20:3,758,290...3,762,927

G

lymphocyte antigen 6 family member H

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LY6H mRNA

NCBI chr 7:109,139,527...109,142,108
Ensembl chr 7:109,139,527...109,246,799

G

lymphocyte antigen 6 family member K

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LY6K mRNA

NCBI chr 7:108,572,732...108,575,450
Ensembl chr 7:108,572,732...108,575,450

G

lysozyme G1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of LYG1 5' UTR

NCBI chr 9:47,666,938...47,678,687
Ensembl chr 9:47,666,938...47,678,687

G

LYR motif containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LYRM1 mRNA

NCBI chr 1:183,715,941...183,736,406
Ensembl chr 1:183,715,468...183,736,406

G

LysM domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of LYSMD1 mRNA

NCBI chr 2:185,394,145...185,403,475

G

lysosomal trafficking regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of LYST mRNA

NCBI chr17:93,225,509...93,427,650
Ensembl chr17:93,225,540...93,427,650

G

leucine zipper transcription factor-like 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of LZTFL1 mRNA

NCBI chr 8:132,222,339...132,237,757
Ensembl chr 8:132,222,342...132,237,684

G

mab-21 like 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAB21L4 mRNA

NCBI chr 9:101,138,408...101,148,516
Ensembl chr 9:101,138,408...101,147,915

G

macoilin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MACO1 mRNA

NCBI chr 5:152,296,107...152,358,684
Ensembl chr 5:152,296,558...152,358,684

G

mitotic arrest deficient 1 like 1

increases methylation
decreases methylation

ISO

Asbestos, Crocidolite results in increased methylation of MAD1L1 gene
Asbestos, Crocidolite results in decreased methylation of MAD1L1 gene

NCBI chr12:19,434,782...19,744,574
Ensembl chr12:19,434,746...19,744,567

G

mitotic arrest deficient 2 like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAD2L1 mRNA

NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222

G

macrophage erythroblast attacher, E3 ubiquitin ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAEA mRNA

NCBI chr14:81,581,784...81,615,246
Ensembl chr14:81,581,785...81,615,202

G

MAF bZIP transcription factor F

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of MAFF mRNA
Asbestos, Crocidolite affects the expression of MAFF mRNA

PMID:18687144 PMID:25757056

NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147

G

MAGE family member B16

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAGEB16 mRNA

NCBI chr X:47,580,752...47,665,173
Ensembl chr X:47,580,439...47,665,225

G

membrane associated guanylate kinase, WW and PDZ domain containing 3

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of MAGI3 5' UTR

NCBI chr 2:194,206,587...194,405,468
Ensembl chr 2:194,206,934...194,405,157

G

mago homolog B, exon junction complex subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAGOHB mRNA

NCBI chr 4:166,765,558...166,773,406
Ensembl chr 4:166,765,618...166,773,851

G

magnesium transporter 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAGT1 mRNA

NCBI chr X:75,104,040...75,145,247
Ensembl chr X:75,106,172...75,145,365

G

MAM domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAMDC2 mRNA

NCBI chr 1:230,290,482...230,443,014
Ensembl chr 1:230,290,499...230,442,711

G

mastermind-like transcriptional coactivator 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAML1 mRNA

NCBI chr10:35,089,715...35,124,100
Ensembl chr10:35,089,715...35,124,100

G

mastermind-like transcriptional coactivator 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAML2 mRNA

NCBI chr 8:18,552,480...18,869,923
Ensembl chr 8:18,552,281...18,869,900

G

mastermind-like transcriptional coactivator 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAML3 mRNA

NCBI chr 2:137,871,267...138,288,615
Ensembl chr 2:137,871,267...138,287,960

G

mannosidase, alpha, class 1A, member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAN1A mRNA

NCBI chr20:33,745,158...33,928,584
Ensembl chr20:33,745,165...33,928,584

G

microtubule-associated protein 1 light chain 3 beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAP1LC3B mRNA

NCBI chr19:66,571,631...66,582,270
Ensembl chr19:66,574,407...66,584,358
Ensembl chr16:66,574,407...66,584,358

G

mitogen activated protein kinase kinase 1

multiple interactions
affects expression
increases phosphorylation

ISO

MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased expression of SCGB1A1 mRNA]; MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL1A1 mRNA]; MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of COL3A1 mRNA]; MAP2K1 protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of IL6 mRNA]
Asbestos, Crocidolite affects the expression of MAP2K1 mRNA
Asbestos, Crocidolite results in increased phosphorylation of MAP2K1 protein

PMID:18192500 PMID:18314537 PMID:24160326

NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184

G

mitogen activated protein kinase kinase 2

increases phosphorylation

ISO

Asbestos, Crocidolite results in increased phosphorylation of MAP2K2 protein

NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:9,241,310...9,260,940

G

mitogen activated protein kinase kinase 3

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of MAP2K3 mRNA
Asbestos, Crocidolite results in increased expression of MAP2K3 mRNA

PMID:17331233 PMID:18687144

NCBI chr10:46,107,639...46,128,986
Ensembl chr10:46,106,548...46,129,004

G

mitogen activated protein kinase kinase 4

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of MAP2K4 protein

NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,844,034...50,947,185

G

mitogen-activated protein kinase kinase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAP2K6 mRNA

NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,872,546...95,987,721

G

mitogen activated protein kinase kinase kinase 10

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K10 mRNA

NCBI chr 1:92,083,376...92,101,676
Ensembl chr 1:92,083,376...92,101,676

G

mitogen-activated protein kinase kinase kinase 11

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K11 mRNA
Asbestos, Crocidolite results in increased expression of MAP3K11 mRNA

PMID:17331233 PMID:29279043

NCBI chr 1:212,404,685...212,417,986
Ensembl chr 1:212,403,680...212,417,983

G

mitogen activated protein kinase kinase kinase 12

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MAP3K12 promoter

NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:135,508,790...135,515,137

G

mitogen activated protein kinase kinase kinase 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K2 mRNA

NCBI chr18:24,081,444...24,153,940
Ensembl chr18:24,081,444...24,147,323

G

mitogen-activated protein kinase kinase kinase 20

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K20 mRNA
Asbestos, Crocidolite results in decreased expression of MAP3K20 mRNA

PMID:17331233 PMID:29279043

NCBI chr 3:77,538,146...77,697,540
Ensembl chr 3:77,537,956...77,697,538

G

mitogen-activated protein kinase kinase kinase 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K5 mRNA

NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:16,505,596...16,723,898

G

mitogen-activated protein kinase kinase kinase 6

affects expression
decreases methylation

ISO

Asbestos, Crocidolite affects the expression of MAP3K6 mRNA
Asbestos, Crocidolite results in decreased methylation of MAP3K6 promoter

PMID:17331233 PMID:29626692

NCBI chr 5:150,724,029...150,736,113
Ensembl chr 5:150,724,216...150,736,111

G

MAP3K7 C-terminal like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAP3K7CL mRNA

NCBI chr11:40,276,839...40,321,848
Ensembl chr11:40,277,688...40,321,847

G

mitogen-activated protein kinase kinase kinase 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAP3K8 mRNA

NCBI chr17:58,078,175...58,098,455
Ensembl chr17:58,078,320...58,098,452

G

mitogen-activated protein kinase kinase kinase 9

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP3K9 mRNA

NCBI chr 6:107,155,008...107,220,304
Ensembl chr 6:107,161,534...107,220,061

G

mitogen activated protein kinase kinase kinase kinase 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP4K1 mRNA

NCBI chr 1:93,398,460...93,419,996
Ensembl chr 1:93,398,454...93,419,993

G

mitogen activated protein kinase kinase kinase kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAP4K2 mRNA

NCBI chr 1:213,074,360...213,090,042
Ensembl chr 1:213,074,377...213,096,987

G

mitogen-activated protein kinase kinase kinase kinase 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of MAP4K5 mRNA

NCBI chr 6:94,020,079...94,112,943
Ensembl chr 6:94,020,079...94,112,943

G

mitogen activated protein kinase 1

increases expression
decreases expression
increases phosphorylation
multiple interactions
decreases response to substance
decreases phosphorylation
affects localization

ISO
EXP

Asbestos, Crocidolite results in increased expression of MAPK1 protein
Asbestos, Crocidolite results in decreased expression of MAPK1 mRNA
[Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of ELK1 protein; Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein
arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; Antigens, Polyomavirus Transforming promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; Asbestos, Crocidolite results in increased phosphorylation of and affects the localization of MAPK1 protein; MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]
MAPK1 mRNA results in decreased susceptibility to Asbestos, Crocidolite
Asbestos, Crocidolite results in decreased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; EGFR protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]
Asbestos, Crocidolite affects the localization of MAPK1 protein modified form

PMID:11306433 PMID:12495932 PMID:12598305 PMID:14627993 PMID:14737115 More...

NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825

G

mitogen-activated protein kinase 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAPK12 mRNA

NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307

G

mitogen activated protein kinase 14

increases phosphorylation
multiple interactions
decreases expression

ISO

Asbestos, Crocidolite results in increased phosphorylation of MAPK14 protein
Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of MAPK14 protein; Asbestos, Crocidolite results in decreased phosphorylation of and results in decreased activity of MAPK14 protein; Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein; Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]; MAPK14 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of DUSP6 protein]; SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein]; triptolide inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]; Vanadates inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of MAPK14 protein]
Asbestos, Crocidolite results in decreased expression of MAPK14 mRNA

PMID:14962975 PMID:17191120 PMID:17507666 PMID:18314537 PMID:29279043

NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294

G

mitogen activated protein kinase 3

affects localization
increases phosphorylation
multiple interactions
decreases phosphorylation
increases expression

ISO
EXP

Asbestos, Crocidolite affects the localization of MAPK3 protein modified form
[Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of ELK1 protein; Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein
arginyl-glycyl-aspartic acid inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; ITGB1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; Antigens, Polyomavirus Transforming promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; Asbestos, Crocidolite results in increased phosphorylation of and affects the localization of MAPK3 protein; MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
Asbestos, Crocidolite results in decreased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; EGFR protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
Asbestos, Crocidolite results in increased expression of MAPK3 protein

PMID:11306433 PMID:12495932 PMID:12598305 PMID:14627993 PMID:14737115 More...

NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411

G

mitogen-activated protein kinase 7

multiple interactions
increases phosphorylation

ISO

AG 1879 inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK7 protein]; CAT protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK7 protein]; MAPK7 protein affects the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]

NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,669,721...46,675,806

G

mitogen-activated protein kinase 8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAPK8 mRNA

PMID:19446018 PMID:25757056

NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427

G

mitogen-activated protein kinase 9

multiple interactions

ISO

Asbestos, Crocidolite results in decreased expression of and results in decreased phosphorylation of MAPK9 protein

NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228

G

MAPK activated protein kinase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MAPKAPK2 mRNA

NCBI chr13:45,066,027...45,112,326
Ensembl chr13:45,066,031...45,112,326

G

MAPK activated protein kinase 5

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of MAPKAPK5 mRNA]

NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170

G

microtubule-associated protein, RP/EB family, member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAPRE2 mRNA

NCBI chr18:15,303,502...15,444,306
Ensembl chr18:15,303,533...15,442,796

G

membrane associated ring-CH-type finger 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MARCHF2 mRNA

NCBI chr 7:15,183,931...15,209,988
Ensembl chr 7:15,183,925...15,202,002

G

membrane associated ring-CH-type finger 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MARCHF4 mRNA

NCBI chr 9:81,527,703...81,647,448
Ensembl chr 9:81,527,703...81,647,448

G

membrane associated ring-CH-type finger 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MARCHF5 mRNA

NCBI chr 1:244,343,674...244,365,160
Ensembl chr 1:244,343,630...244,366,462

G

myristoylated alanine rich protein kinase C substrate

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MARCKS mRNA

NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882

G

meiosis regulator and mRNA stability factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MARF1 mRNA

NCBI chr10:1,395,271...1,439,974
Ensembl chr10:1,395,282...1,439,974

G

microtubule affinity regulating kinase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MARK3 mRNA

NCBI chr 6:136,447,327...136,537,409
Ensembl chr 6:136,448,531...136,537,404

G

methionyl-tRNA synthetase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MARS1 mRNA

NCBI chr 7:65,006,456...65,023,880
Ensembl chr 7:64,998,544...65,023,753

G

MBL associated serine protease 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MASP2 mRNA

NCBI chr 5:164,319,017...164,332,686
Ensembl chr 5:164,308,991...164,332,705

G

microtubule associated serine/threonine kinase family member 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAST4 mRNA

PMID:25351596 PMID:29279043

NCBI chr 2:35,627,190...36,219,090
Ensembl chr 2:35,627,190...36,218,832

G

matrilin 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of MATN1 5' UTR

NCBI chr 5:148,401,364...148,411,256
Ensembl chr 5:148,401,620...148,411,256

G

matrilin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MATN2 mRNA

PMID:29279043 PMID:29523930

NCBI chr 7:67,380,140...67,529,767
Ensembl chr 7:67,380,168...67,530,153

G

MAU2 sister chromatid cohesion factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MAU2 mRNA

NCBI chr16:19,417,812...19,448,922
Ensembl chr16:19,417,613...19,445,841

G

methyl-CpG binding domain protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MBD1 mRNA

NCBI chr18:70,145,093...70,159,744
Ensembl chr18:70,145,114...70,159,703

G

methyl-CpG binding domain 4 DNA glycosylase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MBD4 mRNA

NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:150,565,655...150,577,578

G

MAP3K12 binding inhibitory protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of MBIP mRNA

NCBI chr 6:79,543,223...79,560,476
Ensembl chr 6:79,543,223...79,560,474

G

muscleblind-like splicing regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MBNL1 mRNA

NCBI chr 2:146,789,570...146,964,136
Ensembl chr 2:146,789,596...146,964,134

G

muscleblind-like splicing regulator 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of MBNL2 mRNA

NCBI chr15:103,792,134...103,949,827
Ensembl chr15:103,792,152...103,949,827

G

myelin basic protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MBP mRNA

NCBI chr18:78,130,652...78,241,174
Ensembl chr18:78,130,325...78,241,174

G

membrane-bound transcription factor peptidase, site 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MBTPS1 mRNA

NCBI chr19:64,470,245...64,521,438
Ensembl chr19:64,470,545...64,521,342

G

MCC regulator of WNT signaling pathway

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of MCC gene

NCBI chr18:37,042,350...37,517,114
Ensembl chr18:37,049,253...37,517,076

G

MCF.2 cell line derived transforming sequence-like

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MCF2L promoter

NCBI chr16:83,209,277...83,355,683
Ensembl chr16:83,209,280...83,354,956

G

MCL1 apoptosis regulator, BCL2 family member

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MCL1 mRNA

PMID:18687144 PMID:25757056

NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782

G

minichromosome maintenance 8 homologous recombination repair factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MCM8 mRNA

NCBI chr 3:140,539,590...140,569,891
Ensembl chr 3:140,539,647...140,569,891

G

minichromosome maintenance domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MCMDC2 mRNA

NCBI chr 5:14,071,609...14,120,435
Ensembl chr 5:14,080,968...14,120,351

G

multiple C2 and transmembrane domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MCTP1 mRNA

PMID:18687144 PMID:25351596

NCBI chr 2:7,798,968...8,493,596
Ensembl chr 2:7,803,382...8,493,596

G

MCTS1, re-initiation and release factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MCTS1 mRNA

NCBI chr X:122,215,602...122,228,101
Ensembl chr X:122,216,439...122,229,631

G

mitochondrial calcium uniporter regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MCUR1 mRNA

NCBI chr17:21,348,490...21,365,614
Ensembl chr17:21,348,012...21,368,764

G

malate dehydrogenase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MDH1 mRNA

NCBI chr14:99,831,934...99,847,227
Ensembl chr14:99,831,615...99,847,232

G

MDM2 proto-oncogene

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MDM2 mRNA

NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791

G

male-enhanced antigen 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MEA1 mRNA

NCBI chr 9:21,797,884...21,801,693
Ensembl chr 9:21,797,887...21,802,216

G

MYST/Esa1-associated factor 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MEAF6 mRNA

NCBI chr 5:142,628,281...142,653,076
Ensembl chr 5:142,628,968...142,656,293

G

mediator complex subunit 12

affects expression

ISO

Asbestos, Crocidolite affects the expression of MED12 mRNA

NCBI chr X:70,444,615...70,467,780
Ensembl chr X:70,444,705...70,467,708

G

mediator complex subunit 13L

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MED13L mRNA

NCBI chr12:43,468,556...43,665,819
Ensembl chr12:43,468,556...43,665,819

G

mediator complex subunit 14

affects expression

ISO

Asbestos, Crocidolite affects the expression of MED14 mRNA

NCBI chr X:12,709,406...12,800,642
Ensembl chr X:12,709,472...12,800,640

G

mediator complex subunit 17

affects expression

ISO

Asbestos, Crocidolite affects the expression of MED17 mRNA

NCBI chr 8:20,382,995...20,401,993
Ensembl chr 8:20,382,995...20,401,993

G

mediator complex subunit 21

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of MED21 mRNA
Asbestos, Crocidolite results in decreased expression of MED21 mRNA

PMID:17331233 PMID:29279043

NCBI chr 4:181,291,191...181,314,504
Ensembl chr 4:181,291,271...181,298,234

G

mediator complex subunit 25

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MED25 mRNA

NCBI chr 1:104,496,447...104,513,061
Ensembl chr 1:104,496,447...104,512,391

G

mediator complex subunit 30

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MED30 mRNA

NCBI chr 7:85,894,638...85,916,373
Ensembl chr 7:85,894,605...85,917,973

G

mediator complex subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MED4 mRNA

NCBI chr15:55,106,079...55,116,354
Ensembl chr15:55,105,998...55,116,429

G

mediator complex subunit 6

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of MED6 mRNA
Asbestos, Crocidolite results in decreased expression of MED6 mRNA

PMID:17331233 PMID:29279043 PMID:29523930

NCBI chr 6:107,001,664...107,015,130
Ensembl chr 6:106,990,116...107,015,130

G

mediator complex subunit 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MED8 mRNA

NCBI chr 5:137,234,028...137,234,912
Ensembl chr 5:137,229,367...137,246,666

G

myocyte enhancer factor 2C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MEF2C mRNA

NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640

G

myocyte enhancer factor 2D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MEF2D mRNA

NCBI chr 2:175,904,332...175,933,451
Ensembl chr 2:175,903,959...175,930,760

G

Meis homeobox 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MEIS1 mRNA

NCBI chr14:97,356,949...97,499,646
Ensembl chr14:97,322,748...97,495,083

G

MER proto-oncogene, tyrosine kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MERTK mRNA

NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:136,383,560...136,500,192

G

MET proto-oncogene, receptor tyrosine kinase

multiple interactions
increases expression

ISO
EXP

FOSL1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of MET mRNA]

NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821

G

meteorin-like, glial cell differentiation regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of METRNL mRNA

NCBI chr10:107,462,148...107,476,143
Ensembl chr10:107,462,109...107,476,135

G

methyltransferase 21A, HSPA lysine

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of METTL21A mRNA

NCBI chr 9:73,400,223...73,484,677
Ensembl chr 9:73,471,813...73,481,339

G

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of METTL3 mRNA

NCBI chr15:27,476,659...27,491,134
Ensembl chr15:27,476,660...27,487,487

G

methyltransferase 5, N6-adenosine

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of METTL5 mRNA

NCBI chr 3:75,033,605...75,046,359
Ensembl chr 3:75,026,861...75,045,831

G

methyltransferase 6, tRNA N3-cytidine

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of METTL6 promoter

NCBI chr16:6,667,971...6,705,385
Ensembl chr16:6,689,248...6,705,359

G

microfibril associated protein 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MFAP5 mRNA

NCBI chr 4:157,399,919...157,422,448
Ensembl chr 4:157,395,597...157,422,448

G

mitofusin 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of MFN2 mRNA

NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495

G

major facilitator superfamily domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MFSD1 mRNA

NCBI chr 2:154,156,167...154,176,209
Ensembl chr 2:154,156,166...154,177,086

G

major facilitator superfamily domain containing 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MFSD11 mRNA

NCBI chr10:102,554,409...102,573,866
Ensembl chr10:102,555,050...102,573,439

G

major facilitator superfamily domain containing 13A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC68A1 mRNA

NCBI chr 1:255,158,338...255,177,731
Ensembl chr 1:255,152,543...255,177,733

G

major facilitator superfamily domain containing 14A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC71A1 mRNA

NCBI chr 2:207,264,081...207,305,880
Ensembl chr 2:207,264,941...207,296,505

G

MAX dimerization protein MGA

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MGA mRNA

NCBI chr 3:127,300,558...127,396,694
Ensembl chr 3:127,328,264...127,394,826

G

beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MGAT3 mRNA

NCBI chr 7:113,614,011...113,640,201
Ensembl chr 7:113,598,059...113,643,481

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MGAT4A mRNA

NCBI chr 9:47,169,229...47,282,577
Ensembl chr 9:47,169,232...47,282,574

G

alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MGAT4B mRNA

NCBI chr10:35,049,421...35,060,307
Ensembl chr10:35,050,512...35,060,309

G

O-6-methylguanine-DNA methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MGMT mRNA

NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:201,140,661...201,367,482

G

microsomal glutathione S-transferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MGST1 mRNA

NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875

G

MICAL-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MICALL1 mRNA

NCBI chr 7:112,557,192...112,587,618
Ensembl chr 7:112,557,192...112,587,618

G

midline 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MID1 mRNA

PMID:29279043 PMID:29523930

NCBI chr X:27,678,248...28,053,049
Ensembl chr X:27,681,867...27,906,105

G

mitochondrial elongation factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIEF1 mRNA

NCBI chr 7:113,666,918...113,679,550
Ensembl chr 7:113,666,901...113,683,977

G

migration and invasion inhibitory protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIIP mRNA

NCBI chr 5:163,575,689...163,582,739
Ensembl chr 5:163,575,437...163,582,873

G

MINDY lysine 48 deubiquitinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MINDY1 mRNA

NCBI chr 2:185,550,026...185,561,987
Ensembl chr 2:185,548,993...185,561,986

G

MINDY lysine 48 deubiquitinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MINDY2 mRNA

NCBI chr 8:80,149,127...80,210,011
Ensembl chr 8:80,130,193...80,208,461

G

MINDY lysine 48 deubiquitinase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MINDY3 mRNA

NCBI chr17:80,454,404...80,532,999
Ensembl chr17:80,454,405...80,532,960

G

microRNA 126a

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of MIR126 mRNA
3-aminobenzamide inhibits the reaction [Asbestos, Crocidolite results in increased expression of MIR126 mRNA]; [Decitabine co-treated with 3-aminobenzamide] inhibits the reaction [Asbestos, Crocidolite results in increased expression of MIR126 mRNA]; Decitabine inhibits the reaction [Asbestos, Crocidolite results in increased expression of MIR126 mRNA]; RTKI cpd promotes the reaction [Asbestos, Crocidolite results in increased expression of MIR126 mRNA]

NCBI chr 3:29,813,150...29,813,267

G

microRNA 130b

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MIR130B mRNA

NCBI chr11:97,384,380...97,384,461
Ensembl chr11:97,384,380...97,384,461

G

microRNA 134

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MIR134 mRNA

NCBI chr 6:134,570,313...134,570,385

G

microRNA 15b

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MIR15B mRNA

NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:155,555,178...155,555,275

G

microRNA 193a

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR193A mRNA

NCBI chr10:65,170,306...65,170,417

G

microRNA 210

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR210 mRNA

NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:205,755,917...205,756,034

G

microRNA 222

multiple interactions
increases expression

ISO

RTKI cpd inhibits the reaction [Asbestos, Crocidolite results in increased expression of MIR222 mRNA]

NCBI chr X:6,022,621...6,022,723
Ensembl chr X:6,022,621...6,022,723

G

microRNA 23a

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MIR23A mRNA

NCBI chr19:40,859,769...40,859,843

G

microRNA 27a

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MIR27A mRNA

NCBI chr19:40,859,603...40,859,689

G

microRNA 28

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR28 mRNA

NCBI chr11:89,480,252...89,480,337

G

microRNA 340

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR340 mRNA

NCBI chr10:34,894,650...34,894,747
Ensembl chr10:34,894,650...34,894,747

G

microRNA 382

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR382 mRNA

NCBI chr 6:134,569,944...134,570,023

G

microRNA 409

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MIR409 mRNA

NCBI chr 6:134,579,185...134,579,261

G

melanocyte inducing transcription factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MITF mRNA

NCBI chr 4:131,965,676...132,177,790
Ensembl chr 4:131,965,714...132,177,790

G

marker of proliferation Ki-67

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MKI67 mRNA

NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593

G

MKKS centrosomal shuttling protein

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of MKKS mRNA
Asbestos, Crocidolite results in increased expression of MKKS mRNA

PMID:25351596 PMID:29523930

NCBI chr 3:144,654,563...144,672,831
Ensembl chr 3:144,654,566...144,672,831

G

muskelin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MKLN1 mRNA

NCBI chr 4:60,939,239...61,095,214
Ensembl chr 4:60,937,817...61,095,210

G

MAPK interacting serine/threonine kinase 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MKNK2 promoter

NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,690,421...9,701,529

G

melan-A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MLANA mRNA

NCBI chr 1:236,883,075...236,897,693
Ensembl chr 1:236,883,075...236,896,880

G

mixed lineage kinase domain like pseudokinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MLKL mRNA

NCBI chr19:56,186,860...56,213,886
Ensembl chr19:56,186,860...56,213,858

G

MAX dimerization protein MLX

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MLX mRNA

NCBI chr10:86,519,517...86,524,607
Ensembl chr10:86,519,864...86,524,772

G

metabolism of cobalamin associated A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MMAA mRNA

NCBI chr19:45,523,352...45,553,602
Ensembl chr19:45,523,379...45,555,375

G

metabolism of cobalamin associated D

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MMADHC mRNA

NCBI chr 3:55,117,832...55,135,735
Ensembl chr 3:55,117,833...55,135,851

G

membrane metallo-endopeptidase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MME mRNA

NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463

G

membrane metallo-endopeptidase-like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MMEL1 mRNA

NCBI chr 5:170,713,602...170,744,058
Ensembl chr 5:170,713,627...170,744,058

G

matrix metallopeptidase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MMP1 mRNA; Asbestos, Crocidolite results in increased expression of MMP1 protein

PMID:16966607 PMID:24160326 PMID:25351596

NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964

G

matrix metallopeptidase 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MMP12 mRNA

PMID:16574944 PMID:29279043

NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:12,866,641...12,884,478

G

matrix metallopeptidase 13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MMP13 mRNA

PMID:16574944 PMID:23917077

NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105

G

matrix metallopeptidase 2

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of MMP2 mRNA
Asbestos, Crocidolite results in increased expression of MMP2 protein

PMID:16574944 PMID:21135415 PMID:23634900 PMID:29279043

NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856

G

matrix metallopeptidase 3

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of MMP3 mRNA
Asbestos, Crocidolite results in decreased expression of MMP3 mRNA

PMID:24160326 PMID:29279043

NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826

G

matrix metallopeptidase 7

increases expression
increases secretion

ISO

Asbestos, Crocidolite results in increased expression of MMP7 mRNA
Asbestos, Crocidolite results in increased secretion of MMP7 protein

PMID:16574944 PMID:33581214

NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:13,133,043...13,140,755

G

matrix metallopeptidase 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MMP9 protein

PMID:16574944 PMID:16966607

NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442

G

MAX network transcriptional repressor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MNT mRNA

NCBI chr10:60,197,654...60,213,221
Ensembl chr10:60,197,948...60,213,209

G

MOB kinase activator 1A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MOB1A mRNA

NCBI chr 4:117,389,278...117,406,255
Ensembl chr 4:117,389,186...117,406,250

G

molybdenum cofactor synthesis 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MOCS2 mRNA

NCBI chr 2:48,237,655...48,249,394
Ensembl chr 2:48,237,655...48,249,394

G

mortality factor 4 like 1

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of MORF4L1 mRNA]

NCBI chr 8:99,522,801...99,544,432
Ensembl chr 8:99,500,898...99,544,331

G

MORN repeat containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MORN2 mRNA

NCBI chr 6:20,471,036...20,477,520

G

motile sperm domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MOSPD1 mRNA

NCBI chr X:138,019,719...138,047,475
Ensembl chr14:86,500,797...86,503,187
Ensembl chr X:86,500,797...86,503,187

G

motile sperm domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MOSPD2 mRNA

NCBI chr X:33,052,063...33,105,550
Ensembl chr X:33,052,004...33,107,635

G

motile sperm domain containing 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MOSPD3 mRNA

NCBI chr12:24,728,012...24,737,078
Ensembl chr12:24,732,008...24,736,244

G

M-phase phosphoprotein 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MPHOSPH8 mRNA

NCBI chr15:34,916,169...34,944,038
Ensembl chr15:34,816,701...34,944,433

G

M-phase specific PLK1 interacting protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MPLKIP mRNA

NCBI chr17:52,069,154...52,071,978
Ensembl chr17:52,069,154...52,071,720

G

myeloperoxidase

increases activity
multiple interactions

ISO
EXP

Asbestos, Crocidolite results in increased activity of MPO protein
NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased activity of MPO protein]

PMID:12051993 PMID:12160931

NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056

G

muscle RAS oncogene homolog

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of MRAS mRNA
Asbestos, Crocidolite affects the expression of MRAS mRNA

PMID:17331233 PMID:29626692

NCBI chr 8:108,823,374...108,886,104
Ensembl chr 8:108,823,374...108,875,911

G

mannose receptor, C type 2

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of MRC2 gene

NCBI chr10:90,761,751...90,823,055
Ensembl chr10:90,761,878...90,823,055

G

MAS related GPR family member X3

affects expression

ISO

Asbestos, Crocidolite affects the expression of MRGPRX3 mRNA

NCBI chr 1:106,857,685...106,883,199
Ensembl chr 1:106,857,687...106,883,145

G

mitochondrial ribosomal protein L15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPL15 mRNA

NCBI chr 5:19,527,745...19,539,061
Ensembl chr 5:19,524,588...19,538,004

G

mitochondrial ribosomal protein L21

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPL21 mRNA

NCBI chr 1:209,958,693...209,987,393
Ensembl chr 1:209,958,082...209,971,750

G

mitochondrial ribosomal protein L27

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPL27 mRNA

NCBI chr10:80,092,327...80,098,105
Ensembl chr10:80,092,324...80,098,085

G

mitochondrial ribosomal protein L33

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPL33 mRNA

NCBI chr 6:30,545,794...30,553,987
Ensembl chr 6:30,545,794...30,553,987

G

mitochondrial ribosomal protein L35

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPL35 mRNA

NCBI chr 4:105,424,076...105,431,844
Ensembl chr 4:105,407,993...105,438,793

G

mitochondrial ribosomal protein L42

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPL42 mRNA

NCBI chr 7:32,004,863...32,028,640
Ensembl chr 7:32,004,777...32,035,104

G

mitochondrial ribosomal protein L48

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPL48 mRNA

NCBI chr 1:164,308,787...164,370,034
Ensembl chr 1:164,308,787...164,370,916

G

mitochondrial ribosomal protein L49

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPL49 mRNA

NCBI chr 1:212,775,357...212,779,364
Ensembl chr 1:212,775,357...212,779,888

G

mitochondrial ribosomal protein L53

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPL53 mRNA

NCBI chr 4:117,173,043...117,173,933

G

mitochondrial ribosomal protein L55

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPL55 mRNA

NCBI chr10:44,488,252...44,491,401
Ensembl chr10:44,488,244...44,491,401

G

mitochondrial ribosomal protein S12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MRPS12 mRNA

NCBI chr 1:93,153,424...93,156,422
Ensembl chr 1:93,153,425...93,159,629

G

mitochondrial ribosomal protein S17

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPS17 mRNA

NCBI chr12:32,584,635...32,587,934
Ensembl chr12:32,584,635...32,587,812

G

mitochondrial ribosomal protein S18C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPS18C mRNA

NCBI chr14:9,116,688...9,122,943

G

mitochondrial ribosomal protein S25

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPS25 mRNA

NCBI chr 4:126,225,449...126,237,212
Ensembl chr 4:126,225,450...126,237,373

G

mitochondrial ribosomal protein S33

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MRPS33 mRNA

NCBI chr 4:69,563,501...69,572,317
Ensembl chr 4:69,563,503...69,572,177

G

myocardin related transcription factor B

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of MRTFB mRNA
Asbestos, Crocidolite results in decreased expression of MRTFB mRNA

PMID:17331233 PMID:29279043

NCBI chr10:1,623,887...1,789,658
Ensembl chr10:1,623,940...1,789,658

G

membrane spanning 4-domains A6A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MS4A6C mRNA

NCBI chr 1:217,826,261...217,839,606
Ensembl chr 1:217,826,261...217,850,013

G

musculin

affects expression

ISO

Asbestos, Crocidolite affects the expression of MSC mRNA

NCBI chr 5:9,330,522...9,336,391
Ensembl chr 5:9,330,544...9,336,857

G

mutS homolog 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MSH3 mRNA

NCBI chr 2:25,179,400...25,320,857
Ensembl chr 2:25,179,400...25,321,102

G

MSL complex subunit 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MSL3 mRNA

PMID:29279043 PMID:29523930

NCBI chr X:29,210,388...29,228,060
Ensembl chr X:29,210,427...29,228,054

G

mesothelin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MSLN mRNA

NCBI chr10:15,276,489...15,285,921
Ensembl chr10:15,275,659...15,282,153

G

microseminoprotein, prostate associated

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MSMP mRNA

NCBI chr 5:62,634,721...62,635,771
Ensembl chr 5:62,634,721...62,635,970

G

moesin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MSN mRNA

NCBI chr X:65,005,546...65,073,512
Ensembl chr X:65,005,458...65,075,129

G

methionine sulfoxide reductase B1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MSRB1 gene

NCBI chr10:14,269,414...14,275,140
Ensembl chr10:14,269,414...14,274,184

G

macrophage stimulating 1 receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MST1R mRNA

NCBI chr 8:117,471,928...117,491,059
Ensembl chr 8:117,475,968...117,490,515

G

mitochondrially encoded cytochrome c oxidase III

decreases expression

EXP

Asbestos, Crocidolite results in decreased expression of COX3 mRNA

NCBI chr MT:8,599...9,382
Ensembl chr MT:8,584...9,367

G

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

decreases expression

EXP

Asbestos, Crocidolite results in decreased expression of ND5 mRNA

NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553

G

metallothionein 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MT1A mRNA

NCBI chr19:10,831,959...10,832,975
Ensembl chr17:79,695,809...79,696,200
Ensembl chr X:79,695,809...79,696,200
Ensembl chr19:79,695,809...79,696,200

G

metallothionein 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of MT2A mRNA

NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709

G

metadherin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTDH mRNA

NCBI chr 7:67,192,592...67,250,819
Ensembl chr 7:67,192,393...67,249,584

G

mitochondrial transcription termination factor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTERF3 mRNA

NCBI chr 7:65,711,654...65,729,926
Ensembl chr 7:65,711,662...65,729,895

G

metal-regulatory transcription factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTF1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 5:142,347,024...142,391,810
Ensembl chr 5:142,347,054...142,391,810

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of MTHFD2 mRNA
Asbestos, Crocidolite results in increased expression of MTHFD2 mRNA

PMID:25757056 PMID:29523930

NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350

G

methylenetetrahydrofolate reductase

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTHFR mRNA
Asbestos, Crocidolite results in increased expression of MTHFR mRNA

PMID:29279043 PMID:29523930

NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:163,748,321...163,768,105

G

myotubularin related protein 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTMR12 mRNA

NCBI chr 2:62,950,722...63,020,319
Ensembl chr 2:62,950,819...63,020,319

G

myotubularin related protein 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTMR7 mRNA

NCBI chr16:58,344,755...58,435,682
Ensembl chr16:58,344,767...58,436,615

G

myotrophin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTPN mRNA

NCBI chr 4:65,126,390...65,153,803
Ensembl chr 4:65,115,980...65,153,924

G

MTSS I-BAR domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MTSS1 mRNA

NCBI chr 7:92,378,228...92,517,444
Ensembl chr 7:92,378,238...92,517,303

G

mevalonate kinase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MVK mRNA

NCBI chr12:47,802,002...47,819,503
Ensembl chr12:47,802,002...47,819,503

G

MX dynamin like GTPase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MX1 mRNA

NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904

G

max dimerization protein 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of MXD1 mRNA
Asbestos, Crocidolite results in decreased expression of MXD1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 4:120,654,731...120,678,972
Ensembl chr 4:120,654,731...120,675,129

G

myeloid-associated differentiation marker

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYADM mRNA

NCBI chr 1:74,779,616...74,796,752
Ensembl chr 1:74,775,698...74,789,710

G

MYB proto-oncogene like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYBL1 mRNA

NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588

G

myosin binding protein C3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYBPC3 mRNA

NCBI chr 3:97,550,974...97,569,216
Ensembl chr 3:97,551,061...97,569,216

G

MYC proto-oncogene, bHLH transcription factor

increases expression

EXP
ISO

Asbestos, Crocidolite results in increased expression of MYC mRNA
Asbestos, Crocidolite results in increased expression of MYC mRNA; Asbestos, Crocidolite results in increased expression of MYC protein

PMID:10783328 PMID:18687144 PMID:23634900

NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028

G

Myc binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYCBP mRNA

NCBI chr 5:141,420,727...141,427,938
Ensembl chr 5:141,420,707...141,430,681

G

myosin heavy chain 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYH10 mRNA

NCBI chr10:53,891,955...54,024,032
Ensembl chr10:53,893,166...54,024,036

G

myosin heavy chain 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYH3 mRNA

NCBI chr10:52,269,185...52,293,000
Ensembl chr10:52,269,185...52,293,000

G

myosin, heavy chain 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYH9 protein

NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:111,224,291...111,304,963

G

myosin light chain 12A

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYL12A mRNA
Asbestos, Crocidolite results in increased expression of MYL12A protein

PMID:29279043 PMID:29553831

NCBI chr 9:118,338,592...118,346,277
Ensembl chr 9:118,338,604...118,342,634

G

myosin light chain 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYL6 protein

NCBI chr 7:1,495,301...1,498,512
Ensembl chr 7:1,495,747...1,498,344

G

myosin light chain 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYL7 mRNA

NCBI chr14:84,994,644...84,997,173
Ensembl chr14:84,993,736...84,997,372

G

myosin light chain 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYL9 mRNA

NCBI chr 3:165,742,020...165,748,409
Ensembl chr 3:165,742,046...165,748,410

G

myosin light chain kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYLK mRNA

NCBI chr11:79,288,243...79,535,450
Ensembl chr11:79,288,243...79,535,659

G

myosin light chain kinase 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MYLK3 promoter

NCBI chr19:37,858,298...37,916,805
Ensembl chr19:37,865,141...37,915,827

G

myosin light chain kinase family, member 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of MYLK4 5' UTR

NCBI chr17:31,877,739...31,956,012
Ensembl chr17:31,896,304...31,947,174

G

myosin XVI

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYO16 mRNA

NCBI chr16:85,586,428...86,066,537
Ensembl chr16:85,586,429...85,973,879

G

myosin XVIIIa

increases expression

ISO

Asbestos, Crocidolite results in increased expression of MYO18A mRNA

NCBI chr10:63,152,303...63,253,543
Ensembl chr10:63,152,103...63,253,543

G

myosin Ib

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYO1B mRNA

NCBI chr 9:57,182,059...57,344,335
Ensembl chr 9:57,181,987...57,344,328

G

myocardin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYOCD mRNA

NCBI chr10:50,332,356...50,426,819
Ensembl chr10:50,332,356...50,426,819

G

myopalladin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of MYPN mRNA

NCBI chr20:25,435,554...25,521,149
Ensembl chr20:25,435,554...25,521,149

G

NEDD4 binding protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of N4BP2 mRNA

NCBI chr14:42,696,415...42,819,535
Ensembl chr14:42,763,601...42,825,039

G

NEDD4 binding protein 2-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of N4BP2L2 mRNA

NCBI chr12:4,972,967...5,038,027
Ensembl chr12:4,972,990...5,033,405

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

affects expression

ISO

Asbestos, Crocidolite affects the expression of NAA15 mRNA

NCBI chr 2:137,608,883...137,671,618
Ensembl chr 2:137,608,797...137,671,619

G

N(alpha)-acetyltransferase 16, NatA auxiliary subunit

affects expression

ISO

Asbestos, Crocidolite affects the expression of NAA16 mRNA

NCBI chr15:61,120,704...61,179,979
Ensembl chr15:61,120,704...61,180,146

G

N(alpha)-acetyltransferase 20, NatB catalytic subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NAA20 mRNA

NCBI chr 3:153,775,351...153,790,129
Ensembl chr 3:153,775,338...153,790,916

G

N(alpha)-acetyltransferase 35, NatC auxiliary subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NAA35 mRNA

NCBI chr17:5,039,897...5,091,916
Ensembl chr17:5,039,911...5,092,418

G

nucleic acid binding protein 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NABP1 mRNA
Asbestos, Crocidolite results in decreased expression of NABP1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 9:57,570,326...57,625,926
Ensembl chr 9:57,618,505...57,626,052

G

NEDD8 activating enzyme E1 subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NAE1 mRNA

NCBI chr19:452,462...478,591
Ensembl chr19:452,432...478,831

G

alpha-N-acetylgalactosaminidase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NAGA mRNA

NCBI chr 7:115,726,438...115,735,494
Ensembl chr 7:115,726,624...115,736,828

G

nicotinamide phosphoribosyltransferase

affects expression

ISO

Asbestos, Crocidolite affects the expression of NAMPT mRNA

NCBI chr 6:55,152,756...55,189,547
Ensembl chr 6:55,151,926...55,189,544

G

Nanog homeobox

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NANOG mRNA

NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:157,615,687...157,623,061

G

N-acetylneuraminic acid phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NANP mRNA

NCBI chr 3:160,289,269...160,302,001
Ensembl chr 3:160,288,830...160,302,002

G

N-acetylneuraminate synthase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NANS mRNA

NCBI chr 5:65,575,970...65,593,164
Ensembl chr 5:65,576,015...65,610,547

G

NSF attachment protein beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NAPB mRNA

NCBI chr 3:156,585,394...156,632,418
Ensembl chr 3:156,585,394...156,632,418

G

neuron navigator 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NAV2 mRNA
Asbestos, Crocidolite results in decreased expression of NAV2 mRNA

PMID:18687144 PMID:25351596

NCBI chr 1:107,799,968...108,458,546
Ensembl chr 1:107,805,096...108,458,546

G

neuron navigator 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NAV3 mRNA

NCBI chr 7:46,938,577...47,726,839
Ensembl chr 7:46,940,670...47,504,893

G

non-SMC condensin II complex, subunit D3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NCAPD3 mRNA

NCBI chr 8:33,696,214...33,765,520
Ensembl chr 8:33,696,270...33,765,518

G

neutral cholesterol ester hydrolase 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NCEH1 mRNA
Asbestos, Crocidolite results in decreased expression of NCEH1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 2:112,003,677...112,064,274
Ensembl chr 2:112,003,502...112,064,272

G

neutrophil cytosolic factor 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NCF4 mRNA

NCBI chr 7:111,705,926...111,723,893
Ensembl chr 7:111,706,520...111,723,898

G

NCK-associated protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NCKAP1 mRNA

NCBI chr 3:85,824,333...85,898,748
Ensembl chr 3:85,824,336...85,898,797

G

nuclear receptor coactivator 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of NCOA1 mRNA

NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924

G

nuclear receptor coactivator 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of NCOA3 mRNA

NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:175,157,821...175,240,631

G

nuclear receptor coactivator 4

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of NCOA4 mRNA
Asbestos, Crocidolite results in decreased expression of NCOA4 mRNA

PMID:17331233 PMID:29279043

NCBI chr16:7,395,502...7,415,846
Ensembl chr16:7,401,802...7,415,840

G

nuclear receptor coactivator 7

affects expression

ISO

Asbestos, Crocidolite affects the expression of NCOA7 mRNA

NCBI chr 1:28,674,614...28,835,891
Ensembl chr 1:28,675,426...28,835,886

G

nuclear receptor co-repressor 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NCOR1 mRNA
Asbestos, Crocidolite results in decreased expression of NCOR1 mRNA

PMID:23634900 PMID:29279043

NCBI chr10:47,498,852...47,641,612
Ensembl chr10:47,498,852...47,640,350

G

Nedd4 family interacting protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDFIP1 mRNA

NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471

G

Nedd4 family interacting protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDFIP2 mRNA

NCBI chr15:88,394,548...88,500,881
Ensembl chr15:88,395,032...88,503,600

G

NDRG family member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NDRG2 mRNA

NCBI chr15:27,074,481...27,087,376
Ensembl chr15:27,074,481...27,083,125

G

N-deacetylase and N-sulfotransferase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDST2 mRNA

NCBI chr15:3,612,775...3,623,061
Ensembl chr15:3,612,775...3,623,061

G

N-deacetylase and N-sulfotransferase 3

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NDST3 5' UTR

NCBI chr 2:214,386,804...214,552,739
Ensembl chr 2:214,389,447...214,539,164

G

NADH:ubiquinone oxidoreductase subunit A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDUFA1 mRNA

NCBI chr X:121,289,904...121,293,555
Ensembl chr X:121,289,925...121,293,555

G

NADH:ubiquinone oxidoreductase subunit A12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NDUFA12 mRNA

NCBI chr 7:30,658,316...30,685,302
Ensembl chr 7:30,658,322...30,686,300

G

NADH:ubiquinone oxidoreductase subunit A3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDUFA3 mRNA

NCBI chr 1:74,512,928...74,515,558
Ensembl chr 1:74,512,928...74,515,558

G

NADH:ubiquinone oxidoreductase subunit A6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NDUFA6 mRNA

NCBI chr 7:115,746,460...115,750,317
Ensembl chr 7:115,746,460...115,750,317

G

NADH:ubiquinone oxidoreductase subunit B8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NDUFB8 mRNA

NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:253,357,841...253,362,936

G

nebulette

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEBL mRNA

NCBI chr17:85,022,953...85,374,848
Ensembl chr17:85,022,963...85,374,172

G

NECAP endocytosis associated 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NECAP2 mRNA

NCBI chr 5:158,653,347...158,665,761
Ensembl chr 5:158,653,347...158,666,901

G

nectin cell adhesion molecule 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NECTIN3 mRNA

NCBI chr11:67,825,296...67,931,999
Ensembl chr11:67,827,137...67,871,383

G

NEDD4 like E3 ubiquitin protein ligase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NEDD4L mRNA

NCBI chr18:60,663,918...60,996,824
Ensembl chr18:60,663,970...60,996,824

G

neural precursor cell expressed, developmentally down-regulated 9

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of NEDD9 mRNA
Asbestos, Crocidolite results in increased expression of NEDD9 mRNA

PMID:25351596 PMID:25757056

NCBI chr17:23,495,531...23,673,780
Ensembl chr17:23,495,492...23,675,668

G

NIMA-related kinase 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEK5 mRNA

NCBI chr16:76,597,857...76,641,113
Ensembl chr16:76,597,747...76,641,832

G

NIMA-related kinase 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEK7 mRNA

NCBI chr13:52,573,730...52,700,869
Ensembl chr13:52,573,730...52,700,823

G

NIMA-related kinase 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEK9 mRNA

NCBI chr 6:110,675,107...110,715,586
Ensembl chr 6:110,675,107...110,715,586

G

nuclear export mediator factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEMF mRNA

NCBI chr 6:93,527,690...93,571,863
Ensembl chr 6:93,527,704...93,571,863

G

nuclear envelope integral membrane protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NEMP2 mRNA

NCBI chr 9:56,353,233...56,372,586
Ensembl chr 9:56,353,233...56,372,493

G

neuraminidase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NEU1 mRNA

PMID:18687144 PMID:29523930

NCBI chr20:3,902,120...3,906,383
Ensembl chr20:3,902,120...3,906,383

G

neuronal differentiation 2

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NEUROD2 5' UTR

NCBI chr10:83,820,092...83,824,277
Ensembl chr10:83,819,663...83,824,885

G

nexilin (F actin binding protein)

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NEXN mRNA

NCBI chr 2:243,846,736...243,878,268
Ensembl chr 2:243,846,433...243,887,114

G

neurofibromin 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of NF1 mRNA

NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,804,266...65,034,946

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

increases response to substance

ISO

NF2 gene mutant form results in increased susceptibility to Asbestos, Crocidolite

PMID:12802287 PMID:16166281

NCBI chr14:83,850,894...83,934,263
Ensembl chr14:83,850,894...83,934,151

G

nuclear factor of activated T-cells 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NFAT5 mRNA

PMID:18687144 PMID:19446018

NCBI chr19:52,108,982...52,196,418
Ensembl chr19:52,109,483...52,196,418

G

nuclear factor of activated T-cells 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NFATC2 mRNA

NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380

G

NFE2 like bZIP transcription factor 3

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NFE2L3 5' UTR

NCBI chr 4:81,837,404...81,865,258
Ensembl chr 4:81,837,404...81,865,532

G

nuclear factor I/A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NFIA mRNA

NCBI chr 5:117,359,006...117,897,391
Ensembl chr 5:117,359,077...117,891,395

G

nuclear factor I/B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NFIB mRNA

NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:101,805,168...102,019,945

G

nuclear factor, interleukin 3 regulated

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NFIL3 mRNA

NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,432,198...12,450,826

G

nuclear factor I X

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NFIX promoter

NCBI chr19:40,259,873...40,356,966
Ensembl chr19:40,260,084...40,353,092

G

nuclear factor kappa B subunit 1

multiple interactions
affects localization
increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased activity of [NFKB1 protein binds to RELA protein]
Asbestos, Crocidolite affects the localization of NFKB1 protein
Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to CXCL8 promoter]; Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite affects the localization of NFKB1 protein]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [NFKB1 protein binds to IL6 promoter]]
Asbestos, Crocidolite results in increased expression of NFKB1 mRNA
Asbestos, Crocidolite affects the expression of NFKB1 mRNA

PMID:8969274 PMID:9378980 PMID:10022265 PMID:12162423 PMID:17322126 More...

NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088

G

nuclear factor kappa B subunit 2

affects expression
decreases expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of NFKB2 mRNA
Asbestos, Crocidolite results in decreased expression of NFKB2 protein
Asbestos, Crocidolite results in increased expression of NFKB2 mRNA

PMID:23634900 PMID:24160326 PMID:25757056

NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637

G

NFKB inhibitor alpha

affects expression
multiple interactions
increases expression

ISO

Asbestos, Crocidolite affects the expression of NFKBIA mRNA
Asbestos, Crocidolite results in decreased expression of and results in increased phosphorylation of NFKBIA protein; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased expression of and results in increased phosphorylation of NFKBIA protein]
Asbestos, Crocidolite results in increased expression of NFKBIA mRNA

PMID:17322126 PMID:17331233 PMID:18687144 PMID:24160326 PMID:25351596 More...

NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072

G

NFKB inhibitor delta

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NFKBID promoter

NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861

G

NFKB inhibitor epsilon

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NFKBIE mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr 9:22,941,037...22,947,872
Ensembl chr 9:22,941,040...22,947,872

G

NFKB inhibitor zeta

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of NFKBIZ mRNA
Asbestos, Crocidolite results in decreased expression of NFKBIZ mRNA

PMID:24160326 PMID:29523930

NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767

G

nuclear transcription factor Y subunit alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NFYA mRNA

NCBI chr 9:20,085,067...20,111,521
Ensembl chr 9:20,085,073...20,111,504

G

neuroguidin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NGDN mRNA

NCBI chr15:32,459,898...32,467,260
Ensembl chr15:32,399,109...32,467,260

G

neuronal guanine nucleotide exchange factor

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NGEF promoter

NCBI chr 9:95,594,823...95,692,381
Ensembl chr 9:95,594,823...95,692,251

G

neugrin, neurite outgrowth associated

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NGRN mRNA

NCBI chr 1:143,622,494...143,628,609
Ensembl chr 1:143,622,731...143,628,609

G

NHERF family PDZ scaffold protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NHERF1 mRNA

NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,901,227...100,919,579

G

NHS actin remodeling regulator

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of NHS mRNA
Asbestos, Crocidolite results in increased expression of NHS mRNA

PMID:18687144 PMID:29523930

NCBI chr X:36,185,067...36,524,711
Ensembl chr X:36,438,178...36,524,708

G

NHS-like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NHSL1 mRNA

NCBI chr 1:14,775,874...15,008,327
Ensembl chr 1:14,705,839...15,008,327

G

ninein-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NINL mRNA

NCBI chr 3:160,208,757...160,275,077
Ensembl chr 3:160,196,883...160,275,108

G

NIPA magnesium transporter 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NIPA2 mRNA

NCBI chr 1:115,935,759...115,960,034
Ensembl chr 1:115,936,063...115,959,913

G

NIPBL, cohesin loading factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NIPBL mRNA

NCBI chr 2:59,126,676...59,314,841
Ensembl chr 2:59,126,676...59,293,277

G

nipsnap homolog 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NIPSNAP2 mRNA

NCBI chr12:32,542,171...32,580,345
Ensembl chr12:32,547,819...32,580,303

G

NKAP domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NKAPD1 mRNA

NCBI chr 8:59,852,037...59,863,295
Ensembl chr 8:59,852,726...59,863,181

G

NK1 homeobox 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NKX1-2 mRNA

NCBI chr 1:196,816,491...196,821,371
Ensembl chr 1:196,816,491...196,821,371

G

NK3 homeobox 1

affects expression
increases expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of NKX3-1 mRNA
Asbestos, Crocidolite results in increased expression of NKX3-1 mRNA
Asbestos, Crocidolite results in decreased expression of NKX3-1 mRNA

PMID:18687144 PMID:24160326 PMID:25351596 PMID:25757056

NCBI chr15:50,883,661...50,886,253
Ensembl chr15:50,883,597...50,886,251

G

NK6 homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NKX6-2 promoter

NCBI chr 1:203,811,582...203,813,122
Ensembl chr 1:203,811,582...203,813,122

G

nemo like kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NLK mRNA

PMID:29279043 PMID:29523930

NCBI chr10:63,965,432...64,089,006

G

NLR family, pyrin domain containing 3

multiple interactions
increases expression

ISO

NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Dactinomycin inhibits the reaction [Asbestos, Crocidolite results in increased expression of NLRP3 mRNA]; Interleukin 1 Receptor Antagonist Protein inhibits the reaction [Asbestos, Crocidolite results in increased expression of NLRP3 mRNA]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of FGF2 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein]; NLRP3 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of HMGB1 protein]; NLRP3 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Asbestos, Crocidolite results in increased expression of NLRP3 mRNA; Asbestos, Crocidolite results in increased expression of NLRP3 protein

PMID:18403674 PMID:23937860 PMID:24885895 PMID:28056339

NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394

G

NME/NM23 family member 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NME5 mRNA

NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,437,781...26,454,828

G

nicotinamide nucleotide transhydrogenase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NNT mRNA

NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:53,144,160...53,237,310

G

nocturnin

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of NOCT mRNA
Asbestos, Crocidolite affects the expression of NOCT mRNA

PMID:18687144 PMID:25757056

NCBI chr 2:137,422,074...137,442,282
Ensembl chr 2:137,422,074...137,442,282

G

nucleotide-binding oligomerization domain containing 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NOD1 3' UTR

NCBI chr 4:85,391,142...85,442,281
Ensembl chr 4:85,391,151...85,441,674

G

nodal growth differentiation factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NODAL mRNA

NCBI chr20:29,911,258...29,919,659
Ensembl chr20:29,911,258...29,919,659

G

nucleolar protein 4-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NOL4L mRNA

NCBI chr 3:162,345,059...162,467,849
Ensembl chr 3:162,348,211...162,468,048

G

nucleolar protein 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NOL9 mRNA

NCBI chr 5:167,829,249...167,849,364
Ensembl chr 5:167,829,264...167,849,366

G

NOP56 ribonucleoprotein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NOP56 mRNA

NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959

G

nitric oxide synthase 2

multiple interactions
increases expression

ISO
EXP

[IFNG protein co-treated with Asbestos, Crocidolite] results in increased expression of NOS2 mRNA; Iron inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 mRNA]; Iron inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 protein]; NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased activity of MPO protein]; NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF mRNA]; NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]
[Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [Asbestos, Crocidolite co-treated with IL1B protein] results in increased expression of NOS2 protein; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 mRNA]
Asbestos, Crocidolite results in increased expression of NOS2 mRNA; Asbestos, Crocidolite results in increased expression of NOS2 protein
Asbestos, Crocidolite analog results in increased expression of NOS2 mRNA; Asbestos, Crocidolite results in increased expression of NOS2 mRNA; Asbestos, Crocidolite results in increased expression of NOS2 protein

PMID:8579364 PMID:9586808 PMID:9698594 PMID:9826428 PMID:11461780 More...

NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880

G

notch receptor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NOTCH1 mRNA

NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613

G

notch receptor 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of NOTCH2 mRNA

NCBI chr 2:188,299,336...188,432,823
Ensembl chr 2:188,299,336...188,432,823

G

notch receptor 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of NOTCH4 mRNA

NCBI chr20:4,164,969...4,189,072
Ensembl chr20:4,161,730...4,189,072

G

notochord homeobox

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NOTO promoter

NCBI chr 4:119,518,663...119,522,902
Ensembl chr 4:119,518,514...119,523,799

G

NADPH oxidase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NOX4 mRNA

NCBI chr 1:150,313,736...150,491,480
Ensembl chr 1:150,313,728...150,491,483

G

NPC intracellular cholesterol transporter 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of NPC1 mRNA
Asbestos, Crocidolite affects the expression of NPC1 mRNA

PMID:18687144 PMID:25757056

NCBI chr18:3,654,237...3,699,853
Ensembl chr18:3,654,237...3,699,800

G

N-acetylneuraminate pyruvate lyase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NPL mRNA

NCBI chr13:68,205,602...68,247,940
Ensembl chr13:68,205,603...68,247,999

G

natriuretic peptide B

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of NPPB 3' UTR

NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310

G

natriuretic peptide receptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NPR2 mRNA

NCBI chr 5:62,678,197...62,697,360
Ensembl chr 5:62,678,367...62,697,343

G

neuroplastin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NPTN mRNA

PMID:29279043 PMID:29523930

NCBI chr 8:67,892,678...67,959,231
Ensembl chr 8:67,892,702...67,959,236

G

NAD(P)H quinone dehydrogenase 1

increases expression
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of NQO1 mRNA; Asbestos, Crocidolite results in increased expression of NQO1 protein
secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of NQO1 mRNA]; secoisolariciresinol diglucoside promotes the reaction [Asbestos, Crocidolite results in increased expression of NQO1 protein]

NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260

G

nuclear receptor subfamily 1, group D, member 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NR1D1 mRNA
Asbestos, Crocidolite results in decreased expression of NR1D1 mRNA

PMID:18687144 PMID:29279043

NCBI chr10:84,224,599...84,231,812
Ensembl chr10:84,224,540...84,231,812

G

nuclear receptor subfamily 1, group D, member 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NR1D2 mRNA
Asbestos, Crocidolite results in decreased expression of NR1D2 mRNA

PMID:18687144 PMID:29279043

NCBI chr15:9,955,034...9,981,329
Ensembl chr15:9,954,906...9,981,330

G

nuclear receptor subfamily 3, group C, member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NR3C2 mRNA

NCBI chr19:47,619,853...47,964,089
Ensembl chr19:47,619,853...47,964,078

G

nuclear receptor subfamily 4, group A, member 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of NR4A1 mRNA
Asbestos, Crocidolite affects the expression of NR4A1 mRNA

PMID:18687144 PMID:25757056

NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041

G

nuclear receptor subfamily 4, group A, member 2

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of NR4A2 mRNA
Asbestos, Crocidolite results in increased expression of NR4A2 mRNA

PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:62,098,743...62,106,769

G

nuclear receptor subfamily 4, group A, member 3

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of NR4A3 mRNA
Asbestos, Crocidolite affects the expression of NR4A3 mRNA

PMID:18687144 PMID:25757056

NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285

G

nuclear receptor subfamily 5, group A, member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NR5A1 mRNA

NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046

G

nuclear receptor subfamily 5, group A, member 2

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NR5A2 gene

NCBI chr13:50,865,253...50,985,107
Ensembl chr13:50,867,920...50,984,938

G

nuclear receptor subfamily 6, group A, member 1

increases expression
increases methylation

ISO

Asbestos, Crocidolite results in increased expression of NR6A1 mRNA
Asbestos, Crocidolite results in increased methylation of NR6A1 5' UTR

PMID:19446018 PMID:29523930

NCBI chr 3:42,904,832...43,094,622
Ensembl chr 3:42,904,832...43,092,951

G

NRAS proto-oncogene, GTPase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NRAS mRNA

NCBI chr 2:193,271,399...193,282,023
Ensembl chr 2:193,271,430...193,278,543

G

NRDE-2, necessary for RNA interference, domain containing

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NRDE2 mRNA

NCBI chr 6:125,137,121...125,177,689
Ensembl chr 6:125,136,635...125,198,616

G

neuronal regeneration related protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NREP mRNA

PMID:20831825 PMID:25351596

NCBI chr18:25,291,219...25,320,742
Ensembl chr18:25,291,219...25,320,742

G

neuregulin 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of NRG1 mRNA
Asbestos, Crocidolite results in increased expression of NRG1 mRNA

PMID:24160326 PMID:29279043

NCBI chr16:65,954,084...67,007,484
Ensembl chr16:65,953,865...66,999,849

G

nuclear receptor interacting protein 1

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of NRIP1 mRNA
Asbestos, Crocidolite results in decreased expression of NRIP1 mRNA

PMID:17331233 PMID:29279043

NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353

G

nuclear receptor interacting protein 2

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NRIP2 5' UTR

NCBI chr 4:163,359,592...163,370,144
Ensembl chr 4:163,360,665...163,370,141

G

neuropilin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NRP2 mRNA

NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:71,616,657...71,731,871

G

neurexin 2

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of NRXN2 gene

NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:213,155,673...213,271,526

G

nuclear receptor binding SET domain protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of NSD1 mRNA

NCBI chr17:9,317,085...9,431,528
Ensembl chr17:9,317,085...9,452,250

G

neuronal vesicle trafficking associated 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NSG2 mRNA

NCBI chr10:16,106,073...16,165,915
Ensembl chr10:16,147,325...16,165,915

G

NOP2/Sun RNA methyltransferase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NSUN6 mRNA

NCBI chr17:82,820,938...82,864,140
Ensembl chr17:82,820,941...82,858,539

G

5'-nucleotidase, cytosolic IIIB

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NT5C3B mRNA

NCBI chr10:85,859,509...85,876,731
Ensembl chr10:85,862,512...85,875,992

G

5'-nucleotidase domain containing 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NT5DC2 mRNA

NCBI chr16:6,328,925...6,336,978
Ensembl chr16:6,328,523...6,336,980

G

5' nucleotidase, ecto

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of NT5E mRNA
Asbestos, Crocidolite results in decreased expression of NT5E mRNA

PMID:18687144 PMID:29279043

NCBI chr 8:98,150,925...98,195,646
Ensembl chr 8:98,150,900...98,195,645

G

neurotrophic receptor tyrosine kinase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NTRK3 mRNA

NCBI chr 1:141,526,192...141,913,575
Ensembl chr 1:141,542,569...141,913,004

G

NUAK family kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NUAK1 mRNA

NCBI chr 7:21,217,729...21,289,608
Ensembl chr 7:21,217,681...21,289,354

G

NUAK family kinase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUAK2 mRNA

NCBI chr13:46,305,744...46,322,755
Ensembl chr13:46,305,975...46,322,748

G

NudC domain containing 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NUDCD3 mRNA

NCBI chr14:85,190,276...85,273,655
Ensembl chr14:85,188,285...85,272,883

G

nudix hydrolase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUDT1 mRNA

NCBI chr12:19,416,411...19,423,448
Ensembl chr12:19,416,411...19,424,158

G

nudix hydrolase 14

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUDT14 mRNA

NCBI chr 6:137,831,382...137,838,370
Ensembl chr 6:137,831,373...137,838,370

G

nudix hydrolase 15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NUDT15 mRNA

NCBI chr15:55,117,312...55,123,983

G

nudix hydrolase 16

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUDT16 mRNA

NCBI chr 8:114,618,706...114,620,761
Ensembl chr 8:114,618,725...114,620,951

G

nudix hydrolase 16 like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NUDT16L1 mRNA

NCBI chr10:11,142,626...11,144,542
Ensembl chr10:11,142,627...11,144,764

G

nuclear mitotic apparatus protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUMA1 protein

NCBI chr 1:165,709,893...165,784,848
Ensembl chr 1:165,709,905...165,784,848

G

nucleoporin 58

increases expression

ISO

Asbestos, Crocidolite results in increased expression of NUP58 mRNA

NCBI chr15:38,534,340...38,583,959
Ensembl chr15:38,533,614...38,583,178

G

nucleoporin 62

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of NUP62 mRNA
Asbestos, Crocidolite affects the expression of NUP62 mRNA

PMID:17331233 PMID:29523930

NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710

G

nucleoporin 88

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NUP88 mRNA

NCBI chr10:56,166,486...56,190,829
Ensembl chr10:56,166,486...56,191,383

G

neurexophilin and PC-esterase domain family member 4

decreases methylation
decreases expression

ISO

Asbestos, Crocidolite results in decreased methylation of NXPE4 5' UTR
Asbestos, Crocidolite results in decreased expression of NXPE4 mRNA

PMID:29279043 PMID:29523930

NCBI chr 8:57,399,199...57,640,629
Ensembl chr 8:57,631,895...57,644,186

G

neurexophilin 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of NXPH1 5' UTR

NCBI chr 4:37,964,325...38,277,364
Ensembl chr 4:38,223,093...38,277,172

G

nuclear transport factor 2-like export factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of NXT2 mRNA

NCBI chr X:110,652,434...110,659,738
Ensembl chr X:110,652,434...110,659,737

G

O-acyl-ADP-ribose deacylase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OARD1 mRNA

NCBI chr 9:20,074,507...20,084,946
Ensembl chr 9:20,083,349...20,084,808

G

2'-5' oligoadenylate synthetase 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OAS1 mRNA

NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128

G

2'-5' oligoadenylate synthetase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OAS2 mRNA

NCBI chr12:41,464,568...41,492,036
Ensembl chr12:41,467,315...41,495,881

G

2'-5'-oligoadenylate synthetase-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OASL mRNA

NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483

G

ornithine aminotransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OAT mRNA

NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:196,777,975...196,797,754

G

OCIA domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OCIAD1 mRNA

NCBI chr14:35,251,891...35,269,440
Ensembl chr14:35,251,333...35,269,283

G

OCRL, inositol polyphosphate-5-phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OCRL mRNA

NCBI chr X:131,955,775...132,018,298
Ensembl chr X:131,967,355...132,018,298

G

ornithine decarboxylase 1

increases expression

EXP

Asbestos, Crocidolite results in increased expression of ODC1 mRNA

NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146

G

O-GlcNAcase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OGA mRNA

NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:254,547,311...254,582,855

G

8-oxoguanine DNA glycosylase

increases expression
increases response to substance
multiple interactions

ISO

Asbestos, Crocidolite results in increased expression of OGG1 mRNA
OGG1 protein mutant form results in increased susceptibility to Asbestos, Crocidolite
OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of CASP3 protein modified form]; OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of HSPA5 protein]; OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of TRP53 protein]

PMID:11181447 PMID:24918270

NCBI chr 4:148,030,237...148,037,599
Ensembl chr 4:148,030,349...148,037,604

G

osteoglycin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OGN mRNA

NCBI chr17:15,238,500...15,259,167
Ensembl chr17:15,238,500...15,259,252

G

O-linked N-acetylglucosamine (GlcNAc) transferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OGT mRNA

NCBI chr X:70,811,317...70,856,123
Ensembl chr X:70,811,319...70,856,123

G

oligodendrocyte transcription factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OLIG1 mRNA

NCBI chr11:44,000,450...44,002,592
Ensembl chr11:44,000,281...44,002,592

G

oxidized low density lipoprotein receptor 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of OLR1 mRNA
Asbestos, Crocidolite results in increased expression of OLR1 mRNA

PMID:23917077 PMID:25757056

NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:164,612,463...164,634,598

G

olfactory receptor 1271

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR8D1 mRNA

NCBI chr 8:48,024,543...48,029,052
Ensembl chr 8:48,024,562...48,029,042

G

olfactory receptor 1433

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2W3 mRNA

NCBI chr10:43,542,833...43,546,698

G

olfactory receptor 1523

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR4D1 mRNA

NCBI chr10:73,205,498...73,206,439

G

olfactory receptor 59

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51E2 mRNA

NCBI chr 1:166,604,972...166,639,634
Ensembl chr 1:166,604,141...166,623,265

G

olfactory marker protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of OMP mRNA

NCBI chr 1:161,851,499...161,852,049

G

one cut homeobox 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ONECUT1 promoter

NCBI chr 8:84,480,066...84,507,848
Ensembl chr 8:84,480,305...84,508,124

G

opioid receptor, mu 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OPRM1 mRNA

NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:45,565,371...45,638,756

G

olfactory receptor family 10 subfamily A member 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR10A3 mRNA

NCBI chr 1:172,291,739...172,292,719
Ensembl chr 1:172,291,739...172,292,740

G

olfactory receptor family 10 subfamily A member 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR10A4 mRNA

NCBI chr 1:170,365,682...170,370,100
Ensembl chr 1:170,368,917...170,369,864

G

olfactory receptor family 10 subfamily C member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR10C1 mRNA

NCBI chr20:1,375,847...1,376,785
Ensembl chr20:1,375,847...1,376,785

G

olfactory receptor family 10 subfamily H member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR10H2 mRNA

NCBI chr 7:13,101,150...13,102,106
Ensembl chr 7:13,101,150...13,102,106

G

olfactory receptor family 10 subfamily W member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OR10W1 mRNA

NCBI chr 1:220,231,270...220,232,220
Ensembl chr 1:220,231,255...220,232,220

G

olfactory receptor family 11 subfamily A member 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR11A1 mRNA

NCBI chr20:1,359,776...1,360,717
Ensembl chr20:1,359,776...1,360,717

G

olfactory receptor family 12 subfamily D member 14C

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR12D2 mRNA

NCBI chr20:1,301,891...1,302,781
Ensembl chr20:1,301,855...1,302,781

G

olfactory receptor family 12 subfamily D member 17

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR12D3 mRNA

NCBI chr20:998,023...998,988
Ensembl chr20:998,023...998,988

G

olfactory receptor family 13 subfamily C member 7

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2S2 mRNA

NCBI chr 5:62,876,908...62,877,867
Ensembl chr 5:62,876,908...62,877,867

G

olfactory receptor family 14 subfamily J member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR14J1 mRNA

NCBI chr20:694,951...695,913
Ensembl chr20:694,951...695,913

G

olfactory receptor family 1 subfamily A member 1B

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1A2 mRNA

NCBI chr10:59,568,684...59,569,628
Ensembl chr10:59,568,684...59,569,628

G

olfactory receptor family 1 subfamily AD member 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1G1 mRNA

NCBI chr10:35,808,668...35,809,579
Ensembl chr10:35,808,668...35,809,579

G

olfactory receptor family 1 subfamily D member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1D2 mRNA

NCBI chr10:59,711,377...59,712,312
Ensembl chr10:59,711,377...59,712,312

G

olfactory receptor family 1 subfamily E member 1E

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1E2 mRNA

NCBI chr10:59,252,890...59,253,825
Ensembl chr10:59,252,890...59,253,825

G

olfactory receptor family 1 subfamily F member 19

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1F2P mRNA

NCBI chr10:12,767,753...12,768,694
Ensembl chr10:12,767,753...12,768,694

G

olfactory receptor family 1 subfamily F member 34

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1F1 mRNA

NCBI chr10:12,830,814...12,839,442

G

olfactory receptor family 1 subfamily I member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1I1 mRNA

NCBI chr 7:11,636,515...11,637,456
Ensembl chr 7:11,636,515...11,637,456

G

olfactory receptor family 1 subfamily J member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OR1J1 mRNA

NCBI chr 3:40,774,464...40,775,405
Ensembl chr 3:40,774,464...40,775,405

G

olfactory receptor family 1 subfamily J member 19

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1J2 mRNA

NCBI chr 3:40,727,817...40,732,751
Ensembl chr 3:40,730,573...40,731,514

G

olfactory receptor family 1 subfamily J member 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1J4 mRNA

NCBI chr 3:40,800,528...40,801,466
Ensembl chr 3:40,800,528...40,801,466

G

olfactory receptor family 1 subfamily Q member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR1Q1 mRNA

NCBI chr 3:40,897,874...40,898,800
Ensembl chr 3:40,897,874...40,898,800

G

olfactory receptor family 2 subfamily B member 2

increases methylation
affects expression

ISO

Asbestos, Crocidolite results in increased methylation of OR2B2 5' UTR
Asbestos, Crocidolite affects the expression of OR2B2 mRNA

PMID:17331233 PMID:29523930

NCBI chr17:47,507,192...47,508,133
Ensembl chr17:47,544,174...47,545,084
Ensembl chr17:47,544,174...47,545,084

G

olfactory receptor family 2 subfamily C member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2C1 mRNA

NCBI chr10:12,189,254...12,190,192
Ensembl chr10:12,189,254...12,190,192

G

olfactory receptor family 2 subfamily H member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2H1 mRNA

NCBI chr20:1,451,227...1,452,165
Ensembl chr20:1,451,227...1,452,165

G

olfactory receptor family 2 subfamily H member 2C

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2H2 mRNA

NCBI chr20:1,404,211...1,405,149
Ensembl chr20:1,404,211...1,405,149

G

olfactory receptor family 2 subfamily L member 13

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2L13 mRNA

NCBI chr11:94,904,565...94,905,503
Ensembl chr11:94,904,565...94,905,503

G

olfactory receptor family 2 subfamily W member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR2W1 mRNA

NCBI chr17:48,307,699...48,308,652
Ensembl chr17:48,307,699...48,308,652

G

olfactory receptor family 3 subfamily A member 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of OR3A1 mRNA
Asbestos, Crocidolite results in increased expression of OR3A1C mRNA

PMID:17331233 PMID:29279043

NCBI chr10:59,645,520...59,646,467
Ensembl chr10:59,645,520...59,646,467

G

olfactory receptor family 3 subfamily A member 1E

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR3A2 mRNA

NCBI chr10:59,521,798...59,522,745
Ensembl chr10:59,521,798...59,522,745

G

olfactory receptor family 4 subfamily D member 2B

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR4D2 mRNA

NCBI chr10:73,190,242...73,191,177
Ensembl chr10:73,189,953...73,210,596

G

olfactory receptor family 4 subfamily N member 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR4N4 mRNA

NCBI chr15:25,968,149...25,969,140
Ensembl chr15:25,968,149...25,969,140

G

olfactory receptor family 51 subfamily B member 17

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51B2 mRNA

NCBI chr 1:167,739,355...167,740,278
Ensembl chr 1:167,739,355...167,740,281

G

olfactory receptor family 51 subfamily B member 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51B4 mRNA

NCBI chr 1:167,729,117...167,730,040
Ensembl chr 1:167,729,117...167,730,040

G

olfactory receptor family 51 subfamily E member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51E1 mRNA

NCBI chr 1:166,554,112...166,564,147
Ensembl chr 1:166,554,061...166,564,105

G

olfactory receptor family 51 subfamily I member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51I1 mRNA

NCBI chr 1:167,914,467...167,915,411
Ensembl chr 1:167,914,467...167,915,411

G

olfactory receptor family 51 subfamily I member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR51I2 mRNA

NCBI chr 1:167,925,559...167,926,497
Ensembl chr 1:167,925,559...167,926,497

G

olfactory receptor family 52 subfamily A member 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR52A1 mRNA

NCBI chr 1:167,594,870...167,595,817

G

olfactory receptor family 52 subfamily D member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR52D1 mRNA

NCBI chr 1:167,990,283...167,991,254
Ensembl chr 1:167,990,283...167,991,254

G

olfactory receptor family 52 subfamily R member 1C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OR52R1 mRNA

NCBI chr 1:166,887,023...166,887,967
Ensembl chr 1:166,887,008...166,887,967

G

olfactory receptor family 5 subfamily P member 52

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR5P3 mRNA

NCBI chr 1:171,193,967...171,197,104
Ensembl chr 1:171,195,780...171,197,096

G

olfactory receptor family 5 subfamily P member 76B

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR5P2 mRNA

NCBI chr 1:172,023,915...172,024,859
Ensembl chr 1:172,023,915...172,024,859

G

olfactory receptor family 5 subfamily V member 1B

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR5V1 mRNA

NCBI chr20:1,163,321...1,164,274
Ensembl chr20:1,163,321...1,164,274

G

olfactory receptor family 6 subfamily A member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR6A2 mRNA

NCBI chr 1:170,239,077...170,240,060
Ensembl chr 1:170,239,077...170,240,060

G

olfactory receptor family 6 subfamily B member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR6B1 mRNA

NCBI chr 4:72,800,004...72,800,939
Ensembl chr 4:72,800,004...72,800,939

G

olfactory receptor family 7 subfamily A member 44

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR7A10 mRNA

NCBI chr 7:11,140,596...11,141,531
Ensembl chr 7:11,140,596...11,141,531

G

olfactory receptor family 7 subfamily C member 70

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR7C2 mRNA

NCBI chr 7:11,461,214...11,468,390
Ensembl chr 7:11,461,214...11,462,176

G

olfactory receptor family 7 subfamily H member 8

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR7D2 mRNA

NCBI chr 8:27,057,213...27,058,178

G

olfactory receptor family 8 subfamily B member 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR8B2 mRNA

NCBI chr 8:47,419,122...47,420,063
Ensembl chr 8:47,419,116...47,420,063

G

olfactory receptor family 8 subfamily B member 8

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR8B8 mRNA

NCBI chr 8:45,882,321...45,883,253
Ensembl chr 8:45,882,321...45,883,253

G

olfactory receptor family 8 subfamily G member 17D

affects expression

ISO

Asbestos, Crocidolite affects the expression of OR8G1 mRNA

NCBI chr 8:48,077,717...48,078,652
Ensembl chr 8:48,077,717...48,078,652

G

origin recognition complex, subunit 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ORC3 mRNA

NCBI chr 5:53,923,264...53,977,869
Ensembl chr 5:53,923,393...53,978,115

G

origin recognition complex, subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ORC4 mRNA

NCBI chr 3:53,700,046...53,743,293
Ensembl chr 3:53,703,615...53,742,264

G

origin recognition complex, subunit 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ORC5 mRNA

NCBI chr 4:13,440,264...13,504,888
Ensembl chr 4:13,440,300...13,504,886

G

OS9, endoplasmic reticulum lectin

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of OS9 3' UTR

NCBI chr 7:64,802,517...64,829,185
Ensembl chr 7:64,802,103...64,829,070

G

oxysterol binding protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OSBP2 mRNA

NCBI chr14:82,808,693...82,970,386
Ensembl chr14:82,808,693...82,970,532

G

oxysterol binding protein-like 6

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of OSBPL6 5' UTR

NCBI chr 3:81,751,020...81,948,186
Ensembl chr 3:81,750,982...81,946,615

G

organic solute carrier partner 1

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of OSCP1 5' UTR; Asbestos, Crocidolite affects the methylation of OSCP1 exon

NCBI chr 5:143,618,186...143,649,765
Ensembl chr 5:143,615,360...143,663,986

G

oxidative stress responsive serine-rich 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OSER1 mRNA

NCBI chr 3:172,486,417...172,504,607
Ensembl chr 3:172,486,440...172,504,597

G

O-sialoglycoprotein endopeptidase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OSGEP mRNA

NCBI chr15:26,610,694...26,618,113
Ensembl chr15:26,610,698...26,618,113

G

oncostatin M receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OSMR mRNA

NCBI chr 2:57,634,517...57,688,802
Ensembl chr 2:57,634,517...57,688,561

G

osteoclastogenesis associated transmembrane protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OSTM1 mRNA

NCBI chr20:47,653,696...47,769,248
Ensembl chr20:47,653,670...47,769,237

G

orthopedia homeobox

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of OTP promoter

NCBI chr 2:27,842,892...27,851,093
Ensembl chr 2:27,842,897...27,851,093

G

OTU deubiquitinase, ubiquitin aldehyde binding 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OTUB1 mRNA

NCBI chr 1:213,816,400...213,824,679
Ensembl chr 1:213,816,400...213,824,679

G

OTU deubiquitinase, ubiquitin aldehyde binding 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OTUB2 mRNA

PMID:25351596 PMID:29279043

NCBI chr 6:128,309,863...128,328,444
Ensembl chr 6:128,299,693...128,328,433

G

OTU deubiquitinase 6B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OTUD6B mRNA

NCBI chr 5:32,979,190...33,011,781
Ensembl chr 5:32,979,147...33,011,568

G

ovo like transcriptional repressor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of OVOL1 mRNA

NCBI chr 1:212,284,601...212,296,106
Ensembl chr 1:212,284,605...212,296,106

G

oxidative stress responsive kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of OXSR1 mRNA

NCBI chr 8:127,850,481...127,941,518
Ensembl chr 8:127,850,484...127,939,750

G

oxytocin receptor

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of OXTR mRNA
Asbestos, Crocidolite results in increased expression of OXTR mRNA

PMID:18687144 PMID:20831825 PMID:25351596

NCBI chr 4:147,154,374...147,171,723
Ensembl chr 4:147,154,374...147,170,750

G

purinergic receptor P2X 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of P2RX1 mRNA

NCBI chr10:58,117,107...58,132,167
Ensembl chr10:58,117,088...58,132,164

G

pyrimidinergic receptor P2Y6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of P2RY6 mRNA

NCBI chr 1:164,707,188...164,742,689
Ensembl chr 1:164,706,116...164,743,588

G

prolyl 3-hydroxylase family member 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of P3H4 mRNA

NCBI chr10:85,838,528...85,845,476
Ensembl chr10:85,838,528...85,845,476

G

poly(A) binding protein, cytoplasmic 4-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PABPC4L mRNA

NCBI chr 2:131,743,939...131,745,929
Ensembl chr 2:131,740,252...131,746,176

G

peptidyl arginine deiminase 2

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of PADI2 5' UTR

NCBI chr 5:158,492,087...158,534,662
Ensembl chr 5:158,492,066...158,534,662

G

platelet-activating factor acetylhydrolase 1b, regulatory subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PAFAH1B1 mRNA

NCBI chr10:60,031,441...60,090,259
Ensembl chr10:60,032,514...60,090,196

G

phenylalanine hydroxylase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PAH mRNA

NCBI chr 7:23,793,096...23,885,631
Ensembl chr 7:23,792,781...23,885,627

G

PAK1 interacting protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PAK1IP1 mRNA

NCBI chr17:23,947,978...23,959,055
Ensembl chr17:23,939,509...23,959,055

G

paralemmin A kinase anchor protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PALM2AKAP2 mRNA

NCBI chr 5:76,976,906...77,443,656
Ensembl chr 5:76,977,112...77,443,656

G

protein associated with LIN7 1, MAGUK p55 family member

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PALS1 mRNA

NCBI chr 6:103,327,965...103,384,543
Ensembl chr 6:103,281,154...103,387,209

G

peptidase domain containing associated with muscle regeneration 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PAMR1 mRNA

NCBI chr 3:109,340,411...109,443,595
Ensembl chr 3:109,341,476...109,443,585

G

pantothenate kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PANK1 mRNA

NCBI chr 1:241,737,371...241,808,126
Ensembl chr 1:241,741,083...241,807,824

G

Pannexin 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PANX1 mRNA

NCBI chr 8:20,128,783...20,171,200
Ensembl chr 8:20,132,165...20,171,200

G

poly (A) polymerase alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PAPOLA mRNA

NCBI chr 6:130,446,236...130,499,371
Ensembl chr 6:130,446,797...130,499,336

G

pappalysin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PAPPA mRNA

NCBI chr 5:83,513,358...83,751,364
Ensembl chr 5:83,513,358...83,751,361

G

par-3 family cell polarity regulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PARD3 mRNA

NCBI chr19:71,977,420...72,527,273
Ensembl chr19:71,977,470...72,526,941

G

Parkinsonism associated deglycase

affects expression

ISO

Asbestos, Crocidolite affects the expression of PARK7 mRNA

NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:166,636,552...166,659,825

G

poly (ADP-ribose) polymerase 1

increases expression
decreases expression
multiple interactions
increases cleavage

ISO

Asbestos, Crocidolite results in increased expression of PARP1 mRNA
Asbestos, Crocidolite results in decreased expression of PARP1 mRNA; Asbestos, Crocidolite results in decreased expression of PARP1 protein
3-aminobenzamide inhibits the reaction [Asbestos, Crocidolite results in increased activity of PARP1 protein]; Asbestos, Crocidolite results in increased expression of and results in increased activity of PARP1 protein
Asbestos, Crocidolite results in increased cleavage of PARP1 protein

PMID:17191120 PMID:19783790 PMID:20616036 PMID:21543585 PMID:32006662

NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567

G

poly (ADP-ribose) polymerase family, member 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PARP6 mRNA

NCBI chr 8:68,912,393...68,944,904
Ensembl chr 8:68,917,388...68,944,898

G

prostate and testis expressed 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PATE2 mRNA

NCBI chr 8:42,271,831...42,283,219
Ensembl chr 8:42,267,732...42,308,199

G

PAT1 homolog 1, processing body mRNA decay factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PATL1 mRNA

NCBI chr 1:218,255,801...218,287,662
Ensembl chr 1:218,255,848...218,287,657

G

paired box 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PAX6 mRNA

NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:112,590,391...112,611,763

G

polysaccharide biosynthesis domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PBDC1 mRNA

NCBI chr X:74,219,713...74,275,954
Ensembl chr X:74,219,713...74,227,418

G

phenazine biosynthesis-like protein domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PBLD1 mRNA

NCBI chr20:25,549,974...25,565,390
Ensembl chr20:25,549,974...25,565,226

G

polybromo 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PBRM1 mRNA

NCBI chr16:6,219,933...6,319,336
Ensembl chr16:6,219,917...6,319,336

G

PBX homeobox 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PBX1 mRNA

NCBI chr13:82,811,664...83,121,447
Ensembl chr13:82,812,131...83,121,066

G

PBX homeobox 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PBX3 mRNA

NCBI chr 3:37,886,241...38,079,956
Ensembl chr 3:37,886,687...38,079,895

G

pyruvate carboxylase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PCX mRNA

NCBI chr 1:211,228,708...211,327,792
Ensembl chr 1:211,228,731...211,329,940

G

poly(rC) binding protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCBP2 mRNA

NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:135,483,856...135,509,412

G

protocadherin related 15

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDH15 promoter

NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958

G

protocadherin 18

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCDH18 mRNA

NCBI chr 2:135,982,929...135,996,917
Ensembl chr 2:135,983,144...135,996,826

G

protocadherin 8

increases expression
decreases methylation

ISO

Asbestos, Crocidolite results in increased expression of PCDH8 mRNA
Asbestos, Crocidolite results in decreased methylation of PCDH8 promoter

PMID:29279043 PMID:29626692

NCBI chr15:61,607,521...61,612,090
Ensembl chr15:61,607,521...61,612,097

G

protocadherin 9

decreases expression
increases methylation

ISO

Asbestos, Crocidolite results in decreased expression of PCDH9 mRNA
Asbestos, Crocidolite results in increased methylation of PCDH9 gene

PMID:18687144 PMID:29523930

NCBI chr15:75,748,472...76,646,644
NCBI chr15:76,078,024...76,127,778
Ensembl chr15:75,749,278...76,645,302

G

protocadherin alpha 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA1 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 10

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA10 promoter

G

protocadherin alpha 11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA11 promoter

G

protocadherin alpha 13

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA13 promoter

G

protocadherin alpha 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA3 promoter

G

protocadherin alpha 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCDHA4 mRNA

NCBI chr18:28,688,274...29,120,227
Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA5 promoter

G

protocadherin alpha 6

decreases expression
decreases methylation

ISO

Asbestos, Crocidolite results in decreased expression of PCDHA6 mRNA
Asbestos, Crocidolite results in decreased methylation of PCDHA6 promoter

PMID:29279043 PMID:29626692

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha 7

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA7 promoter

G

protocadherin alpha 8

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHA8 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin alpha subfamily C, 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHAC1 promoter

G

protocadherin alpha subfamily C, 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHAC2 promoter

Ensembl chr18:28,855,256...29,120,227

G

protocadherin gamma subfamily A, 10

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA10 promoter

NCBI chr18:29,825,926...29,919,095

G

protocadherin gamma subfamily A, 11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA11 promoter

NCBI chr18:29,834,606...29,919,095

G

protocadherin gamma subfamily A, 12

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA12 promoter

NCBI chr18:29,843,897...29,919,095

G

protocadherin gamma subfamily A, 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA3 promoter

NCBI chr18:29,750,383...29,919,095

G

protocadherin gamma subfamily A, 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA4 promoter

NCBI chr18:29,760,777...29,794,877

G

protocadherin gamma subfamily A, 5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA5 promoter

NCBI chr18:29,770,940...29,919,095

G

protocadherin gamma subfamily A, 7

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA7 promoter

NCBI chr18:29,794,252...29,919,095

G

protocadherin gamma subfamily A, 8

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGA8 promoter

NCBI chr18:29,805,113...29,919,095

G

protocadherin gamma subfamily B, 7

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PCDHGB7 promoter

NCBI chr18:29,830,362...29,919,098
Ensembl chr18:29,799,669...29,919,101

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PCK2 mRNA

NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864

G

PCNA clamp associated factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCLAF mRNA

NCBI chr 8:75,311,028...75,328,108
Ensembl chr 8:75,315,707...75,328,106

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCMT1 mRNA
Asbestos, Crocidolite results in increased expression of PCMT1 mRNA

PMID:19446018 PMID:29279043 PMID:29523930

NCBI chr 1:3,932,161...3,980,751
Ensembl chr 1:3,932,161...3,964,848

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCMTD1 mRNA

NCBI chr 5:17,071,629...17,143,803
Ensembl chr 5:17,071,629...17,142,010

G

proliferating cell nuclear antigen

increases expression
multiple interactions
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PCNA protein
Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in increased expression of PCNA protein]
Asbestos, Crocidolite results in decreased expression of PCNA mRNA; Asbestos, Crocidolite results in decreased expression of PCNA protein

PMID:17322126 PMID:21570478 PMID:23634900 PMID:38301883

NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901

G

pecanex 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PCNX1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 6:107,296,704...107,433,576
Ensembl chr 6:107,296,792...107,432,452

G

proprotein convertase subtilisin/kexin type 1 inhibitor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PCSK1N mRNA

NCBI chr X:17,251,963...17,255,405
Ensembl chr X:17,251,965...17,257,360

G

prenylcysteine oxidase 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PCYOX1 mRNA

NCBI chr 4:120,389,545...120,400,382
Ensembl chr 4:120,388,180...120,400,382

G

programmed cell death 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDCD4 mRNA

NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:262,926,656...262,950,189

G

phosphodiesterase 12

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PDE12 mRNA

NCBI chr16:1,926,807...1,932,383
Ensembl chr16:1,922,131...1,932,611

G

phosphodiesterase 3A

increases methylation
decreases methylation

ISO

Asbestos, Crocidolite results in increased methylation of PDE3A gene
Asbestos, Crocidolite results in decreased methylation of PDE3A gene

NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:175,904,077...176,169,270

G

phosphodiesterase 4B

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of PDE4B gene

NCBI chr 5:122,028,956...122,598,267
Ensembl chr 5:122,135,174...122,598,267

G

phosphodiesterase 4D

affects expression

ISO

Asbestos, Crocidolite affects the expression of PDE4D mRNA

NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:42,110,838...43,262,569

G

phosphodiesterase 4D interacting protein

affects expression

ISO

Asbestos, Crocidolite affects the expression of PDE4DIP mRNA

NCBI chr 2:187,982,002...188,178,937
Ensembl chr 2:187,981,878...188,178,869

G

phosphodiesterase 7A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDE7A mRNA

PMID:29279043 PMID:29523930

NCBI chr 2:103,631,655...103,723,057
Ensembl chr 2:103,634,594...103,722,890

G

phosphodiesterase 7B

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDE7B mRNA
Asbestos, Crocidolite results in increased expression of PDE7B mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:16,994,072...17,312,828
Ensembl chr 1:17,002,286...17,312,456

G

platelet derived growth factor receptor beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDGFRB mRNA

NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233

G

PDLIM1 interacting kinase 1 like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDIK1L mRNA

NCBI chr 5:151,778,813...151,793,137
Ensembl chr 5:151,778,837...151,790,557

G

pyruvate dehydrogenase kinase 4

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of PDK4 mRNA
Asbestos, Crocidolite affects the expression of PDK4 mRNA

PMID:20831825 PMID:25757056

NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:34,556,330...34,568,381

G

pyruvate dehydrogenase phosphatase catalytic subunit 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PDP1 mRNA

NCBI chr 5:30,245,699...30,252,494
Ensembl chr 5:30,242,704...30,253,960

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDP2 mRNA

NCBI chr19:392,858...400,529
Ensembl chr19:392,183...400,902

G

3-phosphoinositide dependent protein kinase-1

decreases expression
decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased expression of PDPK1 protein modified form
Asbestos, Crocidolite results in decreased phosphorylation of PDPK1 protein

PMID:17191120 PMID:21570478

NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,610,063...13,679,181

G

p53 and DNA damage regulated 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PDRG1 mRNA

NCBI chr 3:161,937,812...161,943,981
Ensembl chr 3:161,937,815...161,948,995

G

PDS5 cohesin associated factor B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDS5B mRNA

NCBI chr12:5,038,114...5,181,208
Ensembl chr12:5,038,160...5,181,208

G

PDZ domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PDZD2 mRNA

NCBI chr 2:63,111,650...63,497,520
Ensembl chr 2:63,111,650...63,497,478

G

proline, glutamate and leucine rich protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PELP1 mRNA

NCBI chr10:55,593,444...55,610,478
Ensembl chr10:55,593,447...55,610,758

G

period circadian regulator 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PER1 mRNA

NCBI chr10:54,299,002...54,313,804
Ensembl chr10:54,302,641...54,314,211

G

period circadian regulator 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PER3 mRNA

NCBI chr 5:166,740,914...166,778,243
Ensembl chr 5:166,743,050...166,777,999

G

prefoldin subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PFDN1 mRNA

NCBI chr18:28,288,210...28,341,198
Ensembl chr18:28,287,913...28,341,123

G

prefoldin subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PFDN4 mRNA

NCBI chr 3:179,721,765...179,729,901
Ensembl chr 3:179,719,344...179,729,901

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PFKFB3 mRNA

NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052

G

6-phosphogluconolactonase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PGLS mRNA

PMID:29279043 PMID:29523930

NCBI chr16:18,334,299...18,339,785
Ensembl chr16:18,334,299...18,339,785

G

peptidoglycan recognition protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PGLYRP1 mRNA

NCBI chr 1:87,659,863...87,665,048
Ensembl chr 1:87,651,271...87,665,048

G

phosphoglucomutase 2-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PGM2L1 mRNA

NCBI chr 1:163,983,917...164,033,027
Ensembl chr 1:163,983,917...164,033,027

G

progesterone receptor membrane component 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PGRMC1 mRNA

NCBI chr X:120,698,610...120,706,805
Ensembl chr X:120,698,610...120,706,805

G

phosphorylated adaptor for RNA export

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHAX mRNA

NCBI chr18:52,251,231...52,267,916
Ensembl chr18:52,248,709...52,267,915

G

polyhomeotic homolog 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHC1 mRNA

NCBI chr 4:157,182,348...157,205,504
Ensembl chr 4:157,182,348...157,204,709

G

polyhomeotic homolog 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PHC3 mRNA

NCBI chr 2:114,337,180...114,412,132
Ensembl chr 2:114,337,227...114,405,816

G

PHD finger protein 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHF11 mRNA

NCBI chr15:37,568,090...37,592,490
Ensembl chr15:37,568,090...37,591,016

G

PHD finger protein 20-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHF20L1 mRNA

NCBI chr 7:100,219,598...100,285,580
Ensembl chr 7:100,219,639...100,285,580

G

PHD finger protein 21A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHF21A mRNA

NCBI chr 3:98,600,933...98,791,132
Ensembl chr 3:98,613,844...98,787,350

G

PHD finger protein 5A

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of PHF5A mRNA
Asbestos, Crocidolite results in increased expression of PHF5A mRNA

PMID:17331233 PMID:29523930

NCBI chr 7:115,258,609...115,265,174
Ensembl chr 7:115,258,609...115,265,174

G

pleckstrin homology domain interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHIP mRNA

NCBI chr 8:92,656,890...92,771,098
Ensembl chr 8:92,656,890...92,771,021

G

phosphorylase kinase regulatory subunit alpha 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHKA2 mRNA

NCBI chr X:37,979,629...38,102,656
Ensembl chr X:37,979,629...38,102,144

G

phosphorylase kinase regulatory subunit beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHKB mRNA

NCBI chr19:37,179,937...37,383,979
Ensembl chr19:37,186,042...37,383,877

G

pleckstrin homology-like domain, family A, member 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of PHLDA1 mRNA
Asbestos, Crocidolite affects the expression of PHLDA1 mRNA

PMID:18687144 PMID:20831825 PMID:25757056

NCBI chr 7:48,853,690...48,855,894
Ensembl chr 7:48,853,260...48,857,542

G

pleckstrin homology-like domain, family B, member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHLDB2 mRNA

PMID:29279043 PMID:29523930

NCBI chr11:68,321,738...68,540,724
Ensembl chr11:68,355,959...68,540,734

G

PH domain and leucine rich repeat protein phosphatase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHLPP1 mRNA

NCBI chr13:22,823,132...23,045,619
Ensembl chr13:22,823,132...23,045,619

G

phosphatase, orphan 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHOSPHO2 mRNA

NCBI chr 3:74,962,649...74,969,810
Ensembl chr 3:74,962,361...74,970,892

G

phytanoyl-CoA 2-hydroxylase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PHYH mRNA

NCBI chr17:78,238,747...78,255,645
Ensembl chr17:78,238,747...78,255,645

G

phosphatidylinositol 4-kinase type 2 alpha

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PI4K2A mRNA

NCBI chr 1:250,850,440...250,878,399
Ensembl chr 1:250,852,154...250,881,811

G

protein inhibitor of activated STAT, 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PIAS1 mRNA

NCBI chr 8:72,233,566...72,347,085
Ensembl chr 8:72,233,566...72,334,315

G

protein inhibitor of activated STAT, 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of PIAS2 mRNA

NCBI chr18:72,883,008...72,989,486
Ensembl chr18:72,882,890...73,006,662

G

protein inhibitor of activated STAT, 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PIAS4 mRNA

NCBI chr 7:9,197,032...9,210,557
Ensembl chr 7:9,196,896...9,210,527

G

phosphotyrosine interaction domain containing 1

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of PID1 mRNA
Asbestos, Crocidolite results in decreased expression of PID1 mRNA

PMID:24160326 PMID:25757056 PMID:29279043

NCBI chr 9:92,732,471...92,951,168
Ensembl chr 9:92,734,214...92,750,070

G

piezo-type mechanosensitive ion channel component 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIEZO2 mRNA

NCBI chr18:58,738,734...59,115,252
Ensembl chr18:58,738,740...59,115,215

G

PIGB opposite strand 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIGBOS1 mRNA

NCBI chr 8:82,656,376...82,660,745
Ensembl chr 8:82,659,649...82,660,996

G

phosphatidylinositol glycan anchor biosynthesis, class P

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIGP mRNA

NCBI chr11:47,152,601...47,158,766
Ensembl chr11:47,148,465...47,160,082

G

PIH1 domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIH1D1 mRNA

NCBI chr 1:104,774,562...104,781,757
Ensembl chr 1:104,776,082...104,781,756

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIK3C2A mRNA

NCBI chr 1:180,012,248...180,117,786
Ensembl chr 1:180,012,248...180,117,773

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

affects expression

ISO

Asbestos, Crocidolite affects the expression of PIK3CB mRNA

NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:108,474,019...108,579,331

G

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PIK3CD mRNA

NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:165,377,994...165,403,968

G

phosphoinositide-3-kinase regulatory subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIK3R1 mRNA

NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:34,612,946...34,626,347

G

phosphoinositide kinase, FYVE-type zinc finger containing

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIKFYVE mRNA

NCBI chr 9:74,057,488...74,151,610
Ensembl chr 9:74,057,514...74,151,610

G

Pim-3 proto-oncogene, serine/threonine kinase

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of PIM3 mRNA
Asbestos, Crocidolite affects the expression of PIM3 mRNA

PMID:18687144 PMID:24160326

NCBI chr 7:121,822,076...121,836,257
Ensembl chr 7:121,832,742...121,836,259

G

PICALM interacting mitotic regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PIMREG mRNA

NCBI chr10:57,168,136...57,173,713
Ensembl chr10:57,167,797...57,173,063

G

phosphatidylinositol-5-phosphate 4-kinase type 2 beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIP4K2B mRNA

NCBI chr10:83,202,379...83,231,292
Ensembl chr10:83,197,287...83,231,292

G

phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PIP4P2 mRNA

NCBI chr 5:33,057,046...33,104,448
Ensembl chr 5:33,056,684...33,104,451

G

phosphatidylinositol transfer protein, beta

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PITPNB mRNA

NCBI chr12:50,909,140...50,958,193
Ensembl chr12:50,909,143...50,958,140

G

paired-like homeodomain 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PITX3 mRNA

NCBI chr 1:254,942,550...254,955,325
Ensembl chr 1:254,942,608...254,955,336

G

piwi-like RNA-mediated gene silencing 2

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of PIWIL2 5' UTR

NCBI chr15:51,841,104...51,907,729
Ensembl chr15:51,841,405...51,907,819

G

praja ring finger ubiquitin ligase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PJA1 mRNA

NCBI chr X:68,621,101...68,626,001
Ensembl chr X:68,620,084...68,638,407

G

polycystin 2, transient receptor potential cation channel

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PKD2 mRNA

NCBI chr14:5,541,821...5,585,140
Ensembl chr14:5,495,401...5,587,594

G

pyruvate kinase M1/2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PKM protein

NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396

G

protein kinase N1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PKN1 mRNA

NCBI chr19:41,346,855...41,374,832
Ensembl chr19:41,346,860...41,378,395

G

plakophilin 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PKP4 mRNA

NCBI chr 3:64,040,995...64,244,586
Ensembl chr 3:64,141,771...64,244,586

G

phospholipase A2, group IID

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLA2G2D mRNA

NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:156,297,777...156,305,812

G

PLAG1 like zinc finger 1

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of PLAGL1 mRNA
Asbestos, Crocidolite results in decreased expression of PLAGL1 mRNA

PMID:17331233 PMID:29279043

NCBI chr 1:9,297,066...9,337,394
Ensembl chr 1:9,330,204...9,337,394

G

plasminogen activator, urokinase

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PLAU mRNA
Asbestos, Crocidolite results in decreased expression of PLAU mRNA

PMID:18687144 PMID:23634900 PMID:25351596

NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030

G

plasminogen activator, urokinase receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLAUR mRNA; Asbestos, Crocidolite results in increased expression of PLAUR protein

PMID:10536123 PMID:18687144 PMID:25351596

NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130

G

phospholipase C, beta 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLCB4 mRNA

NCBI chr 3:143,405,721...143,775,129
Ensembl chr 3:143,405,950...143,775,113

G

phospholipase C, delta 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PLCD3 gene

NCBI chr10:88,526,802...88,548,116
Ensembl chr10:88,526,802...88,548,069

G

phospholipase C, epsilon 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PLCE1 mRNA

NCBI chr 1:245,655,855...245,964,966
Ensembl chr 1:245,657,080...245,963,828

G

phospholipase C, gamma 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLCG2 mRNA

PMID:23634900 PMID:25351596

NCBI chr19:62,456,196...62,592,684
Ensembl chr19:62,453,259...62,592,684

G

phospholipase C-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLCL1 mRNA

NCBI chr 9:64,395,976...64,733,171
Ensembl chr 9:64,361,520...64,733,171

G

phospholipase D1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PLD1 mRNA

NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:112,777,951...112,976,245

G

phospholipase D family, member 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLD6 mRNA

NCBI chr10:45,078,081...45,080,732
Ensembl chr10:45,077,080...45,087,160

G

plectin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLEC protein

NCBI chr 7:109,768,447...109,829,798
Ensembl chr 7:109,768,447...109,828,089

G

pleckstrin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLEK mRNA

NCBI chr14:95,598,650...95,631,326
Ensembl chr14:95,598,654...95,655,721

G

pleckstrin homology domain containing A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLEKHA1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:194,858,239...194,909,418
Ensembl chr 1:194,851,547...194,909,413

G

pleckstrin homology and FYVE domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLEKHF2 mRNA

NCBI chr 5:28,888,358...28,905,350
Ensembl chr 5:28,868,469...28,923,514

G

pleckstrin homology and RhoGEF domain containing G5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PLEKHG5 promoter

NCBI chr 5:167,860,730...167,904,229
Ensembl chr 5:167,860,794...167,904,229

G

pleckstrin homology, MyTH4 and FERM domain containing H3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLEKHH3 mRNA

NCBI chr10:86,598,749...86,607,482
Ensembl chr10:86,598,754...86,607,165

G

pleckstrin homology domain containing M3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLEKHM3 mRNA

NCBI chr 9:73,659,998...73,819,079
Ensembl chr 9:73,664,817...73,799,503

G

pleckstrin homology domain containing N1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLEKHN1 mRNA

NCBI chr 5:172,087,524...172,095,566
Ensembl chr 5:172,087,055...172,095,374

G

plasminogen receptor with a C-terminal lysine

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PLGRKT mRNA
Asbestos, Crocidolite results in decreased expression of PLGRKT mRNA

PMID:18687144 PMID:29279043

NCBI chr 1:236,512,574...236,526,858
Ensembl chr 1:236,512,580...236,524,840

G

perilipin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLIN2 mRNA

NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:106,202,634...106,258,878

G

perilipin 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLIN3 mRNA

NCBI chr 9:1,198,336...1,210,212
Ensembl chr 9:1,198,336...1,210,231

G

perilipin 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLIN5 mRNA

NCBI chr 9:1,026,910...1,033,352
Ensembl chr 9:1,026,307...1,033,284

G

proteolipid protein 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PLP2 mRNA

NCBI chr X:17,506,153...17,509,552
Ensembl chr X:17,506,059...17,509,550

G

pyridoxal phosphate binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLPBP mRNA

NCBI chr16:71,705,064...71,717,726
Ensembl chr16:71,700,028...71,717,726

G

phospholipid phosphatase 3

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of PLPP3 mRNA
Asbestos, Crocidolite affects the expression of PLPP3 mRNA

PMID:18687144 PMID:24160326 PMID:25757056

NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667

G

phospholipid phosphatase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLPP6 mRNA

NCBI chr 1:236,092,642...236,095,494
Ensembl chr 1:236,090,364...236,101,554

G

pleiotropic regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLRG1 mRNA

NCBI chr 2:170,706,188...170,722,519
Ensembl chr 2:170,706,173...170,722,573

G

plexin A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PLXNA1 mRNA

NCBI chr 4:123,295,165...123,340,132
Ensembl chr 4:123,297,244...123,340,428

G

phorbol-12-myristate-13-acetate-induced protein 1

increases expression
affects expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PMAIP1 mRNA
Asbestos, Crocidolite affects the expression of PMAIP1 mRNA
Asbestos, Crocidolite results in decreased expression of PMAIP1 mRNA

PMID:18687144 PMID:25757056 PMID:29279043

NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382

G

phenylethanolamine-N-methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PNMT mRNA

NCBI chr10:83,881,211...83,882,849
Ensembl chr10:83,881,185...83,882,849

G

pinin, desmosome associated protein

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PNN mRNA
Asbestos, Crocidolite results in decreased expression of PNN mRNA

PMID:25351596 PMID:29523930

NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933

G

purine nucleoside phosphorylase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PNP mRNA

NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162

G

polyribonucleotide nucleotidyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PNPT1 mRNA

NCBI chr14:107,078,486...107,109,628
Ensembl chr14:107,078,469...107,109,628

G

POC5 centriolar protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of POC5 mRNA

NCBI chr 2:29,454,392...29,483,468
Ensembl chr 2:29,454,272...29,485,309

G

protein O-fucosyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POFUT1 mRNA

NCBI chr 3:162,168,855...162,195,798
Ensembl chr 3:162,168,606...162,195,018

G

protein O-glucosyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POGLUT1 mRNA

NCBI chr11:75,704,119...75,731,964
Ensembl chr11:75,703,833...75,733,519

G

DNA polymerase gamma, catalytic subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POLG mRNA

NCBI chr 1:142,792,119...142,808,933
Ensembl chr 1:142,792,119...142,808,838

G

RNA polymerase I subunit H, antisense

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POLR1HAS mRNA

NCBI chr 9:23,596,073...23,597,239
Ensembl chr 9:23,596,073...23,597,239

G

RNA polymerase II subunit B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POLR2B mRNA

NCBI chr14:31,151,534...31,189,222
Ensembl chr14:31,151,390...31,189,222

G

RNA polymerase III subunit C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POLR3C mRNA

NCBI chr 2:186,935,038...186,950,962
Ensembl chr 2:186,935,038...186,950,962

G

RNA polymerase III subunit F

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POLR3F mRNA

NCBI chr 3:152,361,798...152,378,169
Ensembl chr 3:152,361,798...152,378,168

G

POP7 homolog, ribonuclease P/MRP subunit

increases expression

ISO

Asbestos, Crocidolite results in increased expression of POP7 mRNA

NCBI chr12:24,826,161...24,827,202
Ensembl chr12:24,809,994...24,827,522

G

protection of telomeres 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POT1A mRNA

NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:55,170,821...55,228,543

G

POTE ankyrin domain family member 1 like 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of ANKRD30A promoter

NCBI chr 3:118,095,804...118,281,502
Ensembl chr 3:118,098,764...118,281,536

G

POU class 2 homeobox associating factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of POU2AF1 mRNA

NCBI chr 8:60,418,173...60,445,176
Ensembl chr 8:60,436,844...60,445,176

G

POU class 2 homeobox 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of POU2F1 mRNA

NCBI chr13:80,653,602...80,796,279
Ensembl chr13:80,663,714...80,796,356

G

POU class 2 homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of POU2F2 promoter

NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:89,812,093...89,897,564

G

inorganic pyrophosphatase 2

increases methylation
decreases expression

ISO

Asbestos, Crocidolite results in increased methylation of PPA2 5' UTR
Asbestos, Crocidolite results in decreased expression of PPA2 mRNA

PMID:29279043 PMID:29523930

NCBI chr 2:224,472,738...224,552,101
Ensembl chr 2:224,474,823...224,552,628

G

peroxisome proliferator-activated receptor delta

affects expression

ISO

Asbestos, Crocidolite affects the expression of PPARD mRNA

NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707

G

peroxisome proliferator-activated receptor gamma

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPARG mRNA; Asbestos, Crocidolite results in increased expression of PPARG protein

NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104

G

PPARG coactivator 1 alpha

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of PPARGC1A mRNA
Asbestos, Crocidolite results in decreased expression of PPARGC1A mRNA

PMID:17331233 PMID:29279043

NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213

G

PPARG coactivator 1 beta

affects expression

ISO

Asbestos, Crocidolite affects the expression of PPARGC1B mRNA

NCBI chr18:57,029,264...57,131,466
Ensembl chr18:57,029,275...57,131,466

G

pro-platelet basic protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPBP mRNA

NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,586,495...17,587,299

G

phosphopantothenoylcysteine decarboxylase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPCDC mRNA

NCBI chr 8:66,711,115...66,738,782
Ensembl chr 8:66,711,115...66,739,011

G

PTPRF interacting protein alpha 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPFIA3 mRNA

NCBI chr 1:104,953,598...104,982,373
Ensembl chr 1:104,953,598...104,982,278

G

peptidylprolyl isomerase A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPIA protein

NCBI chr14:85,491,223...85,496,884
Ensembl chr14:85,492,484...85,497,115

G

peptidylprolyl isomerase A like 4G

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPIAL4G mRNA

NCBI chr15:79,601,128...80,424,184
Ensembl chr15:80,423,564...80,424,151

G

peptidylprolyl isomerase F

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPIF mRNA

NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954

G

diphosphoinositol pentakisphosphate kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPIP5K2 mRNA

NCBI chr 9:105,727,906...105,838,159
Ensembl chr 9:105,727,911...105,838,157

G

periplakin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPL mRNA

NCBI chr10:10,957,388...11,003,035
Ensembl chr10:10,957,341...11,003,658

G

protein phosphatase, Mg2+/Mn2+ dependent, 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPM1B mRNA

NCBI chr 6:15,399,559...15,460,301
Ensembl chr 6:15,399,562...15,460,756

G

protein phosphatase, Mg2+/Mn2+ dependent, 1D

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPM1D mRNA

NCBI chr10:70,670,026...70,706,030
Ensembl chr10:70,670,020...70,706,256

G

protein phosphatase, Mg2+/Mn2+ dependent, 1E

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPM1E mRNA

NCBI chr10:72,548,906...72,684,702
Ensembl chr10:72,552,469...72,684,546

G

protein phosphatase 1 catalytic subunit gamma

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP1CC mRNA

NCBI chr12:40,043,822...40,061,301
Ensembl chr12:40,043,822...40,061,341

G

protein phosphatase 1, regulatory subunit 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP1R10 mRNA

NCBI chr20:2,827,802...2,842,418
Ensembl chr20:2,827,802...2,842,418

G

protein phosphatase 1, regulatory subunit 12B

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PPP1R12B 5' UTR

NCBI chr13:48,751,256...48,948,933
Ensembl chr13:48,751,477...48,948,922

G

protein phosphatase 1, regulatory subunit 15A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP1R15A mRNA

NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774

G

protein phosphatase 1, regulatory subunit 16B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP1R16B mRNA

NCBI chr 3:167,743,518...167,839,511
Ensembl chr 3:167,743,952...167,839,242

G

protein phosphatase 1, regulatory (inhibitor) subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP1R2 mRNA

NCBI chr11:82,977,634...82,999,426
Ensembl chr11:82,977,515...83,001,083

G

protein phosphatase 1, regulatory subunit 3B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP1R3B mRNA

NCBI chr16:63,533,318...63,545,683
Ensembl chr16:63,532,842...63,549,997

G

protein phosphatase 1, regulatory subunit 3C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP1R3C mRNA

NCBI chr 1:243,873,524...243,878,527
Ensembl chr 1:243,871,704...243,878,835

G

protein phosphatase 1, regulatory subunit 3D

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP1R3D mRNA

NCBI chr 3:185,880,087...185,883,158
Ensembl chr 3:185,876,709...185,883,703

G

protein phosphatase 1, regulatory subunit 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP1R7 mRNA

NCBI chr 9:101,333,472...101,358,589
Ensembl chr 9:101,333,497...101,360,959

G

protein phosphatase 2 catalytic subunit beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP2CB mRNA

NCBI chr16:65,261,178...65,282,658
Ensembl chr16:65,261,181...65,282,634

G

protein phosphatase 2 scaffold subunit A alpha

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP2R1A mRNA

NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:69,213,038...69,238,242

G

protein phosphatase 2, regulatory subunit B, delta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP2R2D mRNA

NCBI chr 1:203,095,536...203,129,895
Ensembl chr 1:203,095,531...203,129,893

G

protein phosphatase 2, regulatory subunit B', gamma

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PPP2R5C 3' UTR

NCBI chr 6:135,282,947...135,419,591
Ensembl chr 6:135,324,067...135,419,597

G

protein phosphatase 4, regulatory subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP4R1 mRNA

NCBI chr 9:112,836,950...112,897,490
Ensembl chr 9:112,838,812...112,897,557

G

protein phosphatase 4, regulatory subunit 3B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PPP4R3B mRNA

NCBI chr14:107,118,116...107,166,121
Ensembl chr14:107,118,131...107,166,134

G

protein phosphatase 4, regulatory subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP4R4 mRNA

NCBI chr 6:128,427,884...128,518,776
Ensembl chr 6:128,427,893...128,528,039

G

protein phosphatase 6, regulatory subunit 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PPP6R3 mRNA

NCBI chr 1:210,122,394...210,236,839
Ensembl chr 1:210,122,394...210,236,809

G

PEAK1 related kinase activating pseudokinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRAG1 mRNA

NCBI chr16:62,791,249...62,844,532
Ensembl chr16:62,786,329...62,844,532

G

PR/SET domain 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRDM1 mRNA

PMID:18687144 PMID:24160326 PMID:25351596

NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088

G

PR/SET domain 15

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PRDM15 gene

NCBI chr11:50,633,973...50,691,624
Ensembl chr11:50,633,973...50,691,823

G

PRELI domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRELID1 mRNA

NCBI chr17:9,310,471...9,313,511
Ensembl chr17:9,310,472...9,313,531

G

prolyl endopeptidase-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PREPL mRNA

NCBI chr 6:15,333,107...15,362,825
Ensembl chr 6:15,333,077...15,363,231

G

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PREX2 mRNA

NCBI chr 5:12,720,683...13,036,077
Ensembl chr 5:12,720,683...13,057,881

G

proteoglycan 2, pro eosinophil major basic protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRG2 mRNA

NCBI chr 3:90,469,192...90,472,759
Ensembl chr 3:90,469,176...90,472,752

G

protein kinase AMP-activated catalytic subunit alpha 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PRKAA1 mRNA

NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450

G

protein kinase AMP-activated catalytic subunit alpha 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PRKAA2 promoter

NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324

G

protein kinase cAMP-activated catalytic subunit beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRKACB mRNA

NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315

G

protein kinase cAMP-dependent type I regulatory subunit beta

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PRKAR1B gene

NCBI chr12:20,606,066...20,738,766
Ensembl chr12:20,618,757...20,738,766

G

protein kinase C, alpha

increases activity
increases expression

ISO

Asbestos, Crocidolite results in increased activity of PRKCA protein
Asbestos, Crocidolite results in increased expression of PRKCA protein

NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572

G

protein kinase C, beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRKCB mRNA

NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740

G

protein kinase C, delta

increases activity
increases expression
affects localization

ISO

Asbestos, Crocidolite results in increased activity of PRKCD protein
Asbestos, Crocidolite results in increased expression of PRKCD protein
Asbestos, Crocidolite affects the localization of PRKCD protein

PMID:12057904 PMID:12626342

NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839

G

protein kinase C, zeta

increases activity
increases expression

ISO

Asbestos, Crocidolite results in increased activity of PRKCZ protein
Asbestos, Crocidolite results in increased expression of PRKCZ protein

NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674

G

protein kinase D3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRKD3 mRNA

NCBI chr 6:21,784,665...21,860,600
Ensembl chr 6:21,784,673...21,860,600

G

protein kinase cGMP-dependent 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PRKG1 gene

NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005

G

protein kinase cGMP-dependent 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRKG2 mRNA

PMID:25351596 PMID:29279043

NCBI chr14:10,864,020...10,972,617
Ensembl chr14:10,864,186...10,972,614

G

prolactin releasing hormone receptor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRLHR mRNA

NCBI chr 1:269,592,735...269,594,422
Ensembl chr 1:269,585,611...269,594,909

G

protamine 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRM3 mRNA

NCBI chr10:5,384,394...5,384,908

G

protein arginine methyltransferase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRMT2 mRNA

NCBI chr20:12,391,388...12,420,096
Ensembl chr20:12,394,268...12,420,108

G

protein arginine methyltransferase 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRMT3 mRNA

NCBI chr 1:108,628,899...108,718,803
Ensembl chr 1:108,626,749...108,718,803

G

prokineticin 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of PROK2 mRNA

NCBI chr 4:133,903,210...133,918,126
Ensembl chr 4:133,903,210...133,917,933

G

prominin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PROM1 mRNA

NCBI chr14:71,202,303...71,307,008
Ensembl chr14:71,202,336...71,307,002

G

pre-mRNA processing factor 39

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRPF39 mRNA

NCBI chr 6:88,825,227...88,851,342
Ensembl chr 6:88,825,243...88,851,341

G

pre-mRNA processing factor 40 homolog B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRPF40B mRNA

NCBI chr 7:132,271,469...132,332,913
Ensembl chr 7:132,310,927...132,332,912

G

pre-mRNA processing factor 8

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PRPF8 mRNA

NCBI chr10:60,829,778...60,852,887
Ensembl chr10:60,829,778...60,852,887

G

proline rich 14-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRR14L mRNA

NCBI chr14:82,094,360...82,160,985
Ensembl chr14:82,094,358...82,158,323

G

proline rich 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRR3 mRNA

NCBI chr20:2,797,677...2,804,674
Ensembl chr20:2,797,105...2,798,617

G

proline rich 9

affects expression

ISO

Asbestos, Crocidolite affects the expression of PRR9 mRNA

NCBI chr 2:180,295,095...180,296,461
Ensembl chr 2:180,295,095...180,296,461

G

paired related homeobox 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of PRRX1 mRNA

NCBI chr13:78,136,783...78,205,379
Ensembl chr13:78,136,783...78,204,058

G

paired related homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of PRRX2 promoter

NCBI chr 3:34,530,331...34,566,284
Ensembl chr 3:34,520,173...34,566,284

G

serine protease 16

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRSS16 mRNA

NCBI chr17:47,210,071...47,225,377
Ensembl chr17:47,210,081...47,217,658

G

serine protease 23

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRSS23 mRNA

NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871

G

peroxiredoxin like 2A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PRXL2A mRNA

NCBI chr16:16,900,697...16,920,521
Ensembl chr16:16,900,699...16,920,561

G

prosaposin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSAP mRNA

NCBI chr20:28,756,951...28,783,422
Ensembl chr20:28,757,181...28,783,421

G

presenilin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSEN2 mRNA

NCBI chr13:94,499,451...94,528,419
Ensembl chr13:94,499,928...94,525,116

G

proteasome 20S subunit alpha 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSMA6 mRNA

NCBI chr 6:78,500,676...78,531,693
Ensembl chr 6:78,500,736...78,531,717

G

proteasome 20S subunit beta 8

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of PSMB8 5' UTR; Asbestos, Crocidolite affects the methylation of PSMB8 exon

NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,654,068...4,657,031

G

proteasome 26S subunit, non-ATPase 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSMD6 mRNA

NCBI chr15:13,532,675...13,542,682
Ensembl chr15:13,532,675...13,542,682

G

proteasome activator subunit 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PSME4 mRNA

NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328

G

proteasome assembly chaperone 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSMG2 mRNA

NCBI chr18:63,478,620...63,493,193

G

proteasome assembly chaperone 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PSMG3 mRNA

NCBI chr12:19,923,288...19,926,205
Ensembl chr12:19,923,288...19,926,205

G

paraspeckle component 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of PSPC1 mRNA
Asbestos, Crocidolite results in decreased expression of PSPC1 mRNA

PMID:18687144 PMID:25351596 PMID:29279043

NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828

G

phosphoserine phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PSPH mRNA

NCBI chr12:32,527,091...32,541,182
Ensembl chr12:32,519,269...32,541,180

G

polypyrimidine tract binding protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTBP3 mRNA

NCBI chr 5:79,108,376...79,194,533
Ensembl chr 5:79,108,376...79,194,508

G

phosphatase and tensin homolog

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTEN protein

NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:240,043,707...240,110,330

G

pancreas associated transcription factor 1a

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTF1A mRNA

NCBI chr17:86,959,621...86,961,475
Ensembl chr17:86,959,621...86,961,475

G

prostaglandin E receptor 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTGER4 mRNA

NCBI chr 2:56,061,699...56,074,594
Ensembl chr 2:56,062,890...56,074,135

G

prostaglandin E synthase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTGES mRNA

NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995

G

prostaglandin reductase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTGR1 mRNA

NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811

G

prostaglandin-endoperoxide synthase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTGS2 mRNA

PMID:18687144 PMID:20831825 PMID:24160326 PMID:25757056

NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320

G

parathyroid hormone-like hormone

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTHLH mRNA

NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:181,919,400...181,930,454

G

protein tyrosine kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTK2 mRNA

NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091

G

protein tyrosine phosphatase 4A2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTP4A2 mRNA

NCBI chr 5:147,449,733...147,476,739
Ensembl chr 5:147,449,490...147,476,738

G

protein tyrosine phosphatase, non-receptor type 13

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTPN13 mRNA

NCBI chr14:6,412,841...6,587,238
Ensembl chr14:6,412,841...6,587,171

G

protein tyrosine phosphatase, non-receptor type 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTPN14 mRNA

NCBI chr13:103,799,473...103,951,708
Ensembl chr13:103,799,494...103,951,708

G

protein tyrosine phosphatase, receptor type, K

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTPRK mRNA

NCBI chr 1:18,557,091...19,056,297
Ensembl chr 1:18,558,365...19,056,107

G

protein tyrosine phosphatase, receptor type, M

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTPRM mRNA

NCBI chr 9:114,086,380...114,791,000
Ensembl chr 9:114,086,380...114,790,477

G

protein tyrosine phosphatase, receptor type N2

affects methylation
increases methylation

ISO

Asbestos, Crocidolite affects the methylation of PTPRN2 gene
Asbestos, Crocidolite results in increased methylation of PTPRN2 gene

NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744

G

protein tyrosine phosphatase, receptor type, O

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTPRO mRNA

NCBI chr 4:171,895,104...172,105,911
Ensembl chr 4:171,895,232...172,105,903

G

peptidyl-tRNA hydrolase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PTRH2 mRNA

NCBI chr10:72,002,450...72,012,606
Ensembl chr10:71,985,245...72,045,352

G

6-pyruvoyl-tetrahydropterin synthase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTS mRNA

NCBI chr 8:59,767,234...59,774,265
Ensembl chr 8:59,765,185...59,774,265

G

pentraxin 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PTX3 mRNA

NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372

G

pseudouridine synthase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PUS3 mRNA

NCBI chr 8:42,168,194...42,176,527
Ensembl chr 8:42,168,251...42,176,522

G

parvalbumin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of PVALB mRNA

NCBI chr 7:111,653,820...111,668,469
Ensembl chr 7:111,653,111...111,668,446

G

PX domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of PXDC1 mRNA

NCBI chr17:30,481,336...30,510,330
Ensembl chr17:30,481,373...30,510,331

G

PYD and CARD domain containing

multiple interactions

ISO

PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased cleavage of CASP1 protein]; PYCARD protein affects the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]

NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419

G

QKI, KH domain containing RNA binding

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of QKI mRNA

NCBI chr 1:52,935,357...53,047,338
Ensembl chr 1:52,935,382...53,047,337

G

pyroglutamylated RFamide peptide receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of QRFPR mRNA

NCBI chr 2:120,981,235...121,025,020
Ensembl chr 2:120,981,235...121,025,020

G

R3H domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of R3HDM1 mRNA

NCBI chr13:42,148,281...42,286,311
Ensembl chr13:42,148,290...42,286,311

G

RAB11 family interacting protein 2

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of RAB11FIP2 5' UTR

NCBI chr 1:268,908,825...269,080,691
Ensembl chr 1:268,909,413...269,079,661

G

RAB27A, member RAS oncogene family

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAB27A mRNA

NCBI chr 8:82,663,373...82,717,267
Ensembl chr 8:82,663,276...82,717,262

G

RAB32, member RAS oncogene family

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RAB32 mRNA

NCBI chr 1:6,766,448...6,781,258
Ensembl chr 1:6,766,455...6,781,258

G

RAB3A interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAB3IP mRNA

NCBI chr 7:54,417,418...54,461,253
Ensembl chr 7:54,418,358...54,447,000

G

RAB5A, member RAS oncogene family

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAB5A mRNA

NCBI chr 9:6,720,057...6,749,456
Ensembl chr 9:6,721,122...6,749,447

G

Rab acceptor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RABAC1 mRNA

NCBI chr 1:89,691,884...89,695,017
Ensembl chr 1:89,691,884...89,695,017

G

Rac family small GTPase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RAC2 mRNA

NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267

G

RAD51 recombinase

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAD51 mRNA
Asbestos, Crocidolite results in increased expression of RAD51 mRNA

PMID:29279043 PMID:29523930

NCBI chr 3:126,554,210...126,578,888
Ensembl chr 3:126,554,190...126,579,469

G

Rap associating with DIL domain

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RADIL gene

NCBI chr12:17,137,872...17,202,021
Ensembl chr12:17,134,935...17,202,021

G

retinoic acid early transcript 1E

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RAET1E mRNA

NCBI chr 1:3,474,487...3,476,431

G

Raf-1 proto-oncogene, serine/threonine kinase

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of RAF1 protein

NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:150,352,160...150,412,813

G

retinoic acid induced 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAI1 mRNA

NCBI chr10:45,412,748...45,507,747
Ensembl chr10:45,447,427...45,507,747

G

retinoic acid induced 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAI14 mRNA

NCBI chr 2:61,273,439...61,411,141
Ensembl chr 2:61,273,439...61,409,791

G

ral guanine nucleotide dissociation stimulator like 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of RGL2 mRNA

NCBI chr20:4,950,379...4,958,315
Ensembl chr20:4,950,381...4,958,135

G

RAN, member RAS oncogene family

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of RAN mRNA
Asbestos, Crocidolite results in increased expression of RAN protein

PMID:17331233 PMID:29553831

NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317

G

RAN binding protein 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RANBP3 mRNA

NCBI chr 9:1,594,344...1,631,587
Ensembl chr 9:1,594,346...1,631,587

G

Rap guanine nucleotide exchange factor 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAPGEF4 mRNA

NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:77,217,039...77,509,978

G

Rap guanine nucleotide exchange factor 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RAPGEF5 mRNA

NCBI chr 6:144,588,162...144,822,908
Ensembl chr 6:144,580,976...144,822,908

G

Rap guanine nucleotide exchange factor 6

affects expression

ISO

Asbestos, Crocidolite affects the expression of RAPGEF6 mRNA

NCBI chr10:39,156,573...39,324,947
Ensembl chr10:39,156,620...39,324,946

G

RAS p21 protein activator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RASA1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 2:17,593,136...17,676,707
Ensembl chr 2:17,593,136...17,676,161

G

RAS p21 protein activator 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RASA3 mRNA

NCBI chr16:82,557,556...82,671,527
Ensembl chr16:82,557,428...82,672,984

G

RAS protein activator like 2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of RASAL2 mRNA
Asbestos, Crocidolite results in decreased expression of RASAL2 mRNA

PMID:18687144 PMID:29279043

NCBI chr13:71,808,740...72,102,723
Ensembl chr13:71,813,261...72,102,723

G

ras related dexamethasone induced 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of RASD1 mRNA

NCBI chr10:45,265,975...45,275,279
Ensembl chr10:45,265,979...45,267,710

G

RAS and EF hand domain containing

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of RASEF mRNA
Asbestos, Crocidolite results in decreased expression of RASEF mRNA

PMID:18687144 PMID:29279043

NCBI chr 5:92,595,148...92,665,526
Ensembl chr 5:92,595,148...92,666,117

G

RasGEF domain family, member 1B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RASGEF1B mRNA

NCBI chr14:10,164,366...10,684,184
Ensembl chr14:10,644,521...10,697,296

G

RAS guanyl releasing protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of RASGRP1 mRNA

NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434

G

RAS guanyl releasing protein 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of RASGRP2 mRNA

NCBI chr 1:213,135,034...213,152,246
Ensembl chr 1:213,136,015...213,151,884

G

RAS guanyl releasing protein 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of RASGRP4 mRNA

NCBI chr 1:93,560,513...93,580,321
Ensembl chr 1:93,560,513...93,580,323

G

RAS-like family 11 member A

affects expression

ISO

Asbestos, Crocidolite affects the expression of RASL11A mRNA

NCBI chr12:13,372,023...13,374,784
Ensembl chr12:13,372,023...13,376,451

G

Ras association domain family member 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of RASSF1 mRNA
Asbestos, Crocidolite affects the expression of RASSF1 mRNA

PMID:17331233 PMID:18687144

NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805

G

Ras association domain family member 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RASSF5 mRNA

NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277

G

RB transcriptional corepressor 1

decreases expression
decreases phosphorylation
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of RB1 protein modified form
Asbestos, Crocidolite results in decreased expression of RB1 mRNA
Asbestos, Crocidolite results in decreased phosphorylation of RB1 protein
Asbestos, Crocidolite affects the expression of RB1 mRNA

PMID:15374964 PMID:17331233 PMID:21570478 PMID:29279043

NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857

G

RB1-inducible coiled-coil 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RB1CC1 mRNA

NCBI chr 5:17,948,522...18,012,434
Ensembl chr 5:17,948,522...18,012,434

G

RB binding protein 6, ubiquitin ligase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RBBP6 mRNA

PMID:18687144 PMID:25351596

NCBI chr 1:186,934,563...186,966,852
Ensembl chr 1:186,934,938...186,966,852

G

RANBP2-type and C3HC4-type zinc finger containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RBCK1 mRNA

NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:161,249,390...161,266,032

G

RNA binding motif protein 14

affects expression

ISO

Asbestos, Crocidolite affects the expression of RBM14 mRNA

NCBI chr 1:211,476,298...211,535,077
Ensembl chr 1:211,523,972...211,535,065

G

RNA binding motif protein 25

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RBM25 mRNA

NCBI chr 6:108,993,119...109,050,159
Ensembl chr 6:109,002,869...109,050,159

G

RNA binding motif protein 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RBM3 mRNA

NCBI chr X:17,020,863...17,024,341
Ensembl chr X:17,020,864...17,024,841

G

RNA binding motif protein 33

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RBM33 mRNA

NCBI chr 4:7,714,660...7,825,469
Ensembl chr 4:7,720,180...7,820,882

G

RNA binding motif protein 47

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of RBM47 gene

NCBI chr14:42,407,226...42,545,304
Ensembl chr14:42,466,335...42,543,163

G

RNA binding motif, single stranded interacting protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RBMS3 mRNA

NCBI chr 8:125,183,311...125,970,239
Ensembl chr 8:125,183,315...126,503,586

G

RNA binding protein, mRNA processing factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RBPMS mRNA

NCBI chr16:64,942,159...65,098,504
Ensembl chr16:64,942,530...65,098,503

G

rabenosyn, RAB effector

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RBSN mRNA

NCBI chr 4:126,239,354...126,269,702
Ensembl chr 4:126,239,902...126,266,904

G

ring finger and CCCH-type domains 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RC3H2 mRNA

NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:41,531,617...41,589,715

G

regulator of calcineurin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RCAN1 mRNA

NCBI chr11:45,108,123...45,188,065
Ensembl chr11:45,108,124...45,118,236

G

RCC1 and BTB domain containing protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RCBTB1 mRNA

NCBI chr15:37,430,453...37,477,920
Ensembl chr15:37,435,070...37,480,803

G

RCC1 like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RCC1L mRNA

NCBI chr12:28,179,205...28,210,462
Ensembl chr12:28,180,154...28,215,151

G

REST corepressor 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RCOR3 mRNA

NCBI chr13:106,156,166...106,196,542
Ensembl chr13:106,157,232...106,196,575

G

retinol dehydrogenase 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RDH11 mRNA

NCBI chr 6:103,712,373...103,728,247
Ensembl chr 6:103,712,374...103,729,741

G

radixin

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RDX 5' UTR

NCBI chr 8:61,275,792...61,348,260
Ensembl chr 8:61,274,460...61,333,967

G

reversion-inducing-cysteine-rich protein with kazal motifs

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RECK mRNA

NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270

G

RecQ like helicase

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of RECQL mRNA]

NCBI chr 4:177,039,351...177,063,968
Ensembl chr 4:177,035,128...177,063,838

G

receptor accessory protein 3

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of REEP3 5' UTR

NCBI chr20:21,492,695...21,575,138
Ensembl chr20:21,492,721...21,577,521

G

REL proto-oncogene, NF-kB subunit

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of REL mRNA

NCBI chr14:101,891,238...101,922,324
Ensembl chr14:101,891,243...101,921,938

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases phosphorylation
decreases expression
affects localization
increases expression
increases localization

ISO

Asbestos, Crocidolite results in increased activity of [NFKB1 protein binds to RELA protein]
Asbestos, Crocidolite results in increased phosphorylation of RELA protein
Asbestos, Crocidolite results in decreased expression of RELA mRNA
Asbestos, Crocidolite promotes the reaction [RELA protein binds to CXCL8 promoter]; Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite affects the localization of RELA protein]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite promotes the reaction [RELA protein binds to IL6 promoter]]
Asbestos, Crocidolite results in decreased expression of RELA protein
Asbestos, Crocidolite results in increased expression of RELA mRNA
Asbestos, Crocidolite results in increased localization of RELA protein

PMID:8969274 PMID:9378980 PMID:10022265 PMID:12162423 PMID:17322126 More...

NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817

G

RELB proto-oncogene, NF-kB subunit

affects expression

ISO

Asbestos, Crocidolite affects the expression of RELB mRNA

NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:88,385,717...88,413,420

G

RELT-like 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RELL1 3' UTR

NCBI chr14:44,672,121...44,732,081
Ensembl chr14:44,672,224...44,732,088

G

RAB15 effector protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of REP15 mRNA

NCBI chr 4:181,682,588...181,683,661
Ensembl chr 4:181,682,588...181,683,661

G

retroelement silencing factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RESF1 mRNA

NCBI chr 4:184,057,165...184,093,374
Ensembl chr 4:184,057,010...184,098,429

G

reticulophagy regulator family member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RETREG3 mRNA

NCBI chr10:86,529,048...86,552,873
Ensembl chr10:86,529,055...86,552,990

G

replication factor C subunit 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RFC3 mRNA

NCBI chr12:5,836,546...5,847,331
Ensembl chr12:5,836,553...5,847,340

G

replication factor C subunit 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RFC4 mRNA

NCBI chr11:91,254,273...91,268,727
Ensembl chr11:91,254,243...91,268,730

G

RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RFNG mRNA

PMID:29279043 PMID:29523930

NCBI chr10:106,545,543...106,548,644
Ensembl chr10:106,545,543...106,548,644

G

raftlin lipid raft linker 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RFTN1 mRNA

NCBI chr 9:18,302,143...18,499,819
Ensembl chr 9:18,285,934...18,499,819

G

regulator of G-protein signaling 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RGS10 mRNA

NCBI chr 1:192,376,772...192,422,640
Ensembl chr 1:192,376,774...192,418,904

G

regulator of G-protein signaling 12

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of RGS12 mRNA
Asbestos, Crocidolite results in decreased expression of RGS12 mRNA

PMID:25351596 PMID:29279043

NCBI chr14:79,940,561...80,048,637
Ensembl chr14:79,940,565...80,034,859

G

regulator of G-protein signaling 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RGS2 mRNA

NCBI chr13:58,350,063...58,352,666
Ensembl chr13:58,349,163...58,352,697

G

regulator of G-protein signaling 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of RGS3 mRNA

NCBI chr 5:81,037,588...81,177,446
Ensembl chr 5:81,056,068...81,177,445

G

regulator of G-protein signaling 4

affects expression

ISO

Asbestos, Crocidolite affects the expression of RGS4 mRNA

NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884

G

regulator of G-protein signaling 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RGS5 mRNA

NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352

G

regulator of G-protein signaling 7 binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RGS7BP mRNA

NCBI chr 2:37,867,698...37,965,587
Ensembl chr 2:37,872,949...37,965,253

G

regulator of G-protein signaling 8

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of RGS8 gene

NCBI chr13:68,355,078...68,399,412
Ensembl chr13:68,355,157...68,399,412

G

rhomboid like 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RHBDL3 gene

NCBI chr10:65,797,145...65,851,949
Ensembl chr10:65,797,209...65,851,937

G

Rh family, C glycoprotein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RHCG mRNA

NCBI chr 1:142,941,046...142,965,242
Ensembl chr 1:142,941,048...142,965,376

G

ras homolog family member A

multiple interactions
decreases prenylation

ISO

Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]; Asbestos, Crocidolite results in decreased activity of and results in decreased lipidation of RHOA protein; Mevalonic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased lipidation of RHOA protein]; tempol inhibits the reaction [Asbestos, Crocidolite inhibits the reaction [RHOA protein binds to Guanosine Triphosphate]]; tempol inhibits the reaction [Asbestos, Crocidolite results in decreased prenylation of RHOA protein]

PMID:17322126 PMID:21257924

NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302

G

Rho-related BTB domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RHOBTB1 mRNA

NCBI chr20:19,326,197...19,455,182
Ensembl chr20:19,326,212...19,402,057

G

ras homolog family member G

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RHOG mRNA

NCBI chr 1:166,030,685...166,046,254
Ensembl chr 1:166,017,427...166,044,787

G

ras homolog family member T1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RHOT1 mRNA

NCBI chr10:65,685,687...65,760,682
Ensembl chr10:65,696,571...65,760,681

G

RIC1 homolog, RAB6A GEF complex partner 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RIC1 mRNA

NCBI chr 1:236,698,901...236,798,099
Ensembl chr 1:236,698,852...236,798,099

G

RIC8 guanine nucleotide exchange factor B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RIC8B mRNA

NCBI chr 7:20,636,337...20,730,066
Ensembl chr 7:20,636,687...20,730,178

G

ribosomal modification protein rimK-like family member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RIMKLB mRNA

NCBI chr 4:157,336,950...157,396,970
Ensembl chr 4:157,344,414...157,378,727

G

regulating synaptic membrane exocytosis 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RIMS1 5' UTR

NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772

G

RIO kinase 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RIOK3 mRNA

NCBI chr18:3,602,535...3,628,108
Ensembl chr18:3,602,535...3,628,108

G

receptor interacting serine/threonine kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RIPK1 mRNA

NCBI chr17:31,044,983...31,077,167
Ensembl chr17:31,044,994...31,077,167

G

receptor-interacting serine-threonine kinase 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of RIPK2 mRNA

NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663

G

receptor-interacting serine-threonine kinase 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RIPK3 promoter

NCBI chr15:33,253,071...33,262,025
Ensembl chr15:33,253,071...33,262,025

G

Ras-like without CAAX 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RIT1 mRNA

NCBI chr 2:176,478,616...176,493,269
Ensembl chr 2:176,478,596...176,494,684

G

RLF zinc finger

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of RLF mRNA
Asbestos, Crocidolite results in increased expression of RLF mRNA

PMID:18687144 PMID:29279043

NCBI chr 5:139,996,782...140,052,419
Ensembl chr 5:139,996,782...140,052,419

G

ring finger protein, LIM domain interacting

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RLIM mRNA

NCBI chr X:73,048,983...73,070,302
Ensembl chr X:73,054,098...73,069,992

G

regulator of MON1-CCZ1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RMC1 mRNA

NCBI chr18:3,634,604...3,654,519
Ensembl chr18:3,634,588...3,654,549

G

required for meiotic nuclear division 5 homolog A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RMND5A mRNA

NCBI chr 4:104,934,160...104,991,088
Ensembl chr 4:104,934,160...104,991,088

G

ribonuclease A family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNASE2 mRNA

NCBI chr15:26,923,125...26,923,934
Ensembl chr15:26,923,134...26,923,955

G

ribonuclease A family member 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNASE4 mRNA

NCBI chr15:26,786,287...26,803,634
Ensembl chr15:26,786,079...26,803,639

G

ribonuclease H2, subunit C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNASEH2C mRNA

NCBI chr 1:212,323,916...212,325,011
Ensembl chr 1:212,323,939...212,329,571

G

ribonuclease L

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNASEL mRNA

NCBI chr13:68,446,641...68,460,804
Ensembl chr13:68,446,882...68,459,557

G

Rho family GTPase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RND1 mRNA

NCBI chr 7:131,700,321...131,707,392
Ensembl chr 7:131,700,321...131,707,392

G

Rho family GTPase 3

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of RND3 mRNA
Asbestos, Crocidolite affects the expression of RND3 mRNA

PMID:18687144 PMID:25757056

NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:55,980,355...55,998,536

G

ring finger protein 103

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNF103 mRNA

NCBI chr 4:105,084,762...105,100,839
Ensembl chr 4:105,084,686...105,106,809

G

ring finger protein 111

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF111 mRNA

NCBI chr 8:79,984,831...80,061,022
Ensembl chr 8:79,984,837...80,060,984

G

ring finger protein 114

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNF114 mRNA

NCBI chr 3:176,641,456...176,653,262
Ensembl chr 3:176,641,499...176,671,960

G

ring finger protein 13

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF13 mRNA

NCBI chr 2:144,076,526...144,211,520
Ensembl chr 2:144,077,916...144,211,798

G

ring finger protein 14

affects expression

ISO

Asbestos, Crocidolite affects the expression of RNF14 mRNA

NCBI chr18:30,381,072...30,406,859
Ensembl chr18:30,382,857...30,406,774

G

ring finger protein 145

affects expression

ISO

Asbestos, Crocidolite affects the expression of RNF145 mRNA

NCBI chr10:29,507,779...29,552,153
Ensembl chr10:29,507,772...29,552,151

G

ring finger protein 157

decreases expression
increases methylation

ISO

Asbestos, Crocidolite results in decreased expression of RNF157 mRNA
Asbestos, Crocidolite results in increased methylation of RNF157 gene

NCBI chr10:102,070,842...102,138,738
Ensembl chr10:102,070,842...102,155,802

G

ring finger protein 167

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNF167 mRNA

NCBI chr10:55,859,254...55,863,546
Ensembl chr10:55,859,297...55,863,905

G

ring finger protein 19A, RBR E3 ubiquitin protein ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF19A mRNA

NCBI chr 7:69,310,947...69,350,567
Ensembl chr 7:69,310,947...69,350,225

G

ring finger protein 19B

affects expression

ISO

Asbestos, Crocidolite affects the expression of RNF19B mRNA

NCBI chr 5:146,690,453...146,715,729
Ensembl chr 5:146,690,577...146,714,394

G

ring finger protein 213

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF213 mRNA

NCBI chr10:105,154,873...105,254,148
Ensembl chr10:105,157,904...105,254,148

G

ring finger protein 217

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of RNF217 gene

NCBI chr 1:27,835,741...27,927,805
Ensembl chr 1:27,835,148...27,928,044

G

ring finger protein 25

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF25 mRNA

NCBI chr 9:83,619,148...83,626,020
Ensembl chr 9:83,619,149...83,627,263

G

ring finger protein 32

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF32 mRNA

NCBI chr 4:6,822,700...6,884,411
Ensembl chr 4:6,824,970...6,883,976

G

ring finger protein 34

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF34 mRNA

NCBI chr12:39,364,461...39,385,391
Ensembl chr12:39,355,578...39,385,340

G

ring finger protein 38

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF38 mRNA

NCBI chr 5:63,154,507...63,263,138
Ensembl chr 5:63,154,507...63,263,137

G

ring finger protein 39

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNF39 mRNA

NCBI chr20:1,610,027...1,615,516
Ensembl chr20:1,610,026...1,612,323

G

ring finger protein 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNF4 mRNA

NCBI chr14:80,625,864...80,647,138
Ensembl chr14:80,625,866...80,647,148

G

ring finger protein, transmembrane 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RNFT2 mRNA

NCBI chr12:43,990,113...44,048,215
Ensembl chr12:43,990,304...44,048,213

G

RNA (guanine-7-) methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNMT mRNA

NCBI chr18:64,156,067...64,179,601
Ensembl chr18:64,156,154...64,179,500

G

RNA-binding region (RNP1, RRM) containing 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RNPC3 mRNA

PMID:29279043 PMID:29523930

NCBI chr 2:204,121,191...204,145,128
Ensembl chr 2:204,121,193...204,145,128

G

roundabout guidance receptor 1

decreases expression
decreases methylation

ISO

Asbestos, Crocidolite results in decreased expression of ROBO1 mRNA
Asbestos, Crocidolite results in decreased methylation of ROBO1 5' UTR

PMID:23917077 PMID:29523930

NCBI chr11:24,067,869...25,108,694
Ensembl chr11:24,067,878...25,108,694

G

Rho-associated coiled-coil containing protein kinase 1

multiple interactions

ISO

ROCK1 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]

NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147

G

Rho-associated coiled-coil containing protein kinase 2

multiple interactions
decreases expression

ISO

ROCK2 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]
Asbestos, Crocidolite results in decreased expression of ROCK2 mRNA

PMID:24760326 PMID:29279043

NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:45,407,965...45,502,771

G

replication protein A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPA1 mRNA

NCBI chr10:60,647,185...60,698,279
Ensembl chr10:60,647,185...60,698,279

G

ribosome production factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPF1 mRNA

NCBI chr 2:238,063,294...238,077,817
Ensembl chr 2:238,063,295...238,078,838

G

retinitis pigmentosa GTPase regulator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPGR mRNA

NCBI chr X:15,238,961...15,299,004
Ensembl chr X:15,239,159...15,298,999

G

ribosomal protein L10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPL10 mRNA

NCBI chr X:157,205,850...157,208,057
Ensembl chr X:157,205,836...157,208,049

G

ribosomal protein L13A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPL13A mRNA

NCBI chr 1:104,746,223...104,748,975
Ensembl chr 1:104,746,223...104,748,914

G

ribosomal protein L21

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPL21 mRNA

NCBI chr12:13,382,516...13,386,153
Ensembl chr12:13,382,516...13,386,153
Ensembl chr13:13,382,516...13,386,153

G

ribosomal protein L22

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPL22 mRNA

NCBI chr 5:168,114,432...168,126,114
Ensembl chr 5:168,111,074...168,126,114
Ensembl chr 4:168,111,074...168,126,114
Ensembl chr 7:168,111,074...168,126,114

G

ribosomal protein L22 like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPL22L1 mRNA

NCBI chr 2:113,683,196...113,685,132
Ensembl chr 2:113,683,196...113,685,132

G

ribosomal protein L3

decreases expression
affects methylation

ISO

Asbestos, Crocidolite results in decreased expression of RPL3 mRNA
Asbestos, Crocidolite affects the methylation of RPL3 gene

PMID:19446018 PMID:29523930

NCBI chr 7:113,491,943...113,508,115
Ensembl chr 7:113,501,960...113,507,990

G

ribosomal protein L7-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPL7L1 mRNA

NCBI chr 9:21,695,718...21,703,736
Ensembl chr 9:21,695,707...21,703,735

G

ribosomal protein L9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPL9 mRNA

NCBI chr14:43,247,536...43,250,784
Ensembl chr14:43,247,588...43,250,782
Ensembl chr 1:43,247,588...43,250,782

G

ribosomal protein lateral stalk subunit P1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPLP1 protein

NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:71,289,535...71,290,872

G

ribosomal protein lateral stalk subunit P2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPLP2 protein

NCBI chr 1:205,975,598...205,978,192
Ensembl chr 1:205,975,894...205,978,191

G

ribonuclease P/MRP subunit p30

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPP30 mRNA

NCBI chr 1:243,198,647...243,221,559
Ensembl chr 1:243,198,713...243,221,553

G

regulation of nuclear pre-mRNA domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPRD2 mRNA

NCBI chr 2:186,000,375...186,056,943
Ensembl chr 2:186,000,316...186,056,943

G

ribosomal protein S10 like 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS10-NUDT3 protein

NCBI chr15:20,788,028...21,277,092
Ensembl chr15:20,787,968...20,788,849

G

ribosomal protein S11

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS11 mRNA
Asbestos, Crocidolite results in decreased expression of RPS11 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:104,742,155...104,744,337

G

ribosomal protein S13

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPS13 mRNA
Asbestos, Crocidolite results in increased expression of RPS13 protein

PMID:29279043 PMID:29553831

NCBI chr 1:180,007,230...180,009,660
Ensembl chr 1:180,002,471...180,009,660

G

ribosomal protein S19

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS19 protein

NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132

G

ribosomal protein s25

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPS25 mRNA

NCBI chr 8:53,630,333...53,632,810
Ensembl chr 8:53,629,861...53,632,808
Ensembl chr 8:53,629,861...53,632,808

G

ribosomal protein S27

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPS27 mRNA

NCBI chr 2:177,963,499...177,964,708
Ensembl chr 2:177,963,496...177,964,607
Ensembl chr12:177,963,496...177,964,607

G

ribosomal protein S27a

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS27A protein

NCBI chr14:107,486,664...107,488,941
Ensembl chr 5:138,465,088...138,466,080
Ensembl chr14:138,465,088...138,466,080
Ensembl chr 5:138,465,088...138,466,080

G

ribosomal protein S27-like

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS27L mRNA

NCBI chr 8:76,443,658...76,448,593
Ensembl chr12:33,713,661...33,714,130
Ensembl chr 8:33,713,661...33,714,130

G

ribosomal protein S4, X-linked

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPS4X protein

NCBI chr X:71,338,478...71,342,921
Ensembl chr X:71,338,479...71,342,921
Ensembl chr 4:71,338,479...71,342,921

G

ribosomal protein S6

affects expression

ISO

Asbestos, Crocidolite affects the expression of RPS6 protein

NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:106,417,680...106,420,566

G

ribosomal protein S6 kinase A3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPS6KA3 mRNA

NCBI chr X:39,325,926...39,432,017
Ensembl chr X:39,325,926...39,433,678

G

ribosomal protein S6 kinase B1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RPS6KB1 protein modified form

NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238

G

ribosomal protein SA

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RPSA mRNA

NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:128,728,862...128,732,737

G

Ras-related GTP binding C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RRAGC mRNA

NCBI chr 5:141,433,014...141,452,546
Ensembl chr 5:141,433,040...141,452,548

G

Ras-related GTP binding D

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RRAGD mRNA

NCBI chr 5:52,170,234...52,205,700
Ensembl chr 5:52,169,783...52,209,000

G

RAS related

affects expression

ISO

Asbestos, Crocidolite affects the expression of RRAS mRNA

NCBI chr 1:104,637,061...104,640,841
Ensembl chr 1:104,634,951...104,640,841

G

ras responsive element binding protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of RREB1 mRNA

NCBI chr17:27,082,217...27,208,061
Ensembl chr17:27,082,227...27,208,061

G

ribonucleotide reductase catalytic subunit M1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RRM1 mRNA

NCBI chr 1:166,235,904...166,260,206
Ensembl chr 1:166,235,900...166,260,944

G

ribonucleotide reductase regulatory subunit M2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RRM2 mRNA

NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370

G

RRN3 homolog, RNA polymerase I transcription factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RRN3 mRNA

NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,637,016...2,672,330

G

ribosomal RNA processing 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RRP12 mRNA

NCBI chr 1:250,621,707...250,655,318
Ensembl chr 1:250,621,707...250,655,318

G

remodeling and spacing factor 1

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of RSF1 mRNA
Asbestos, Crocidolite results in decreased expression of RSF1 mRNA
Asbestos, Crocidolite affects the expression of RSF1 mRNA

PMID:17331233 PMID:18687144 PMID:29279043

NCBI chr 1:161,303,596...161,426,326
Ensembl chr 1:161,303,660...161,420,290

G

ribosomal L24 domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RSL24D1 mRNA

NCBI chr 8:82,733,627...82,742,632
Ensembl chr 8:82,733,649...82,744,497

G

arginine and serine rich coiled-coil 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RSRC2 mRNA

NCBI chr12:38,500,709...38,520,715
Ensembl chr12:38,500,770...38,520,707

G

RT1 class Ia, locus A2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of H2-T23 mRNA

NCBI chr20:4,872,720...4,876,425

G

RT1 class I, locus CE16

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of H2-Q1 mRNA

NCBI chr20:3,261,656...3,265,548

G

RNA 3'-terminal phosphate cyclase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RTCA mRNA

NCBI chr 2:207,140,090...207,161,366
Ensembl chr 2:207,140,091...207,161,366

G

retrotransposon Gag like 8A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RTL8C mRNA

NCBI chr X:138,436,824...138,438,037
Ensembl chr X:138,436,605...138,470,972

G

RUNX family transcription factor 1

increases expression
decreases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of RUNX1 mRNA
Asbestos, Crocidolite results in decreased expression of RUNX1 mRNA
Asbestos, Crocidolite affects the expression of RUNX1 mRNA

PMID:17331233 PMID:23917077 PMID:25757056 PMID:29279043

NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925

G

RUNX family transcription factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of RUNX2 mRNA

NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027

G

retinoid X receptor alpha

affects expression

ISO

Asbestos, Crocidolite affects the expression of RXRA mRNA

NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417

G

RING1 and YY1 binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of RYBP mRNA

NCBI chr 4:134,432,663...134,484,732
Ensembl chr 4:134,432,663...134,484,930

G

S100 calcium binding protein A11

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of S100A11 mRNA
Asbestos, Crocidolite results in increased expression of S100A11 protein

PMID:29279043 PMID:29553831

NCBI chr 2:181,875,132...181,880,542
Ensembl chr 2:181,875,130...181,880,541

G

S100 calcium binding protein A13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of S100A13 mRNA

NCBI chr 2:178,297,020...178,303,514
Ensembl chr 2:178,296,917...178,303,507

G

S100 calcium binding protein A16

increases expression

ISO

Asbestos, Crocidolite results in increased expression of S100A16 mRNA

NCBI chr 2:178,313,986...178,319,696
Ensembl chr 2:178,313,910...178,319,821

G

S100 calcium binding protein A9

affects expression

ISO

Asbestos, Crocidolite affects the expression of S100A9 protein

NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870

G

sphingosine-1-phosphate receptor 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of S1PR2 mRNA

NCBI chr 8:27,779,452...27,790,344
Ensembl chr 8:27,774,566...27,790,577

G

serum amyloid A4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SAA4 mRNA

NCBI chr 1:106,383,856...106,388,158
Ensembl chr 1:106,383,856...106,387,354

G

SAC1 like phosphatidylinositide phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SACM1L mRNA

NCBI chr 8:132,053,465...132,109,857
Ensembl chr 8:132,053,049...132,109,857

G

sterile alpha motif domain containing 4A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SAMD4A mRNA

NCBI chr15:22,616,200...22,831,872
Ensembl chr15:22,614,287...22,831,872

G

sterile alpha motif domain containing 9

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SAMD9 mRNA

NCBI chr 4:32,119,318...32,139,008
Ensembl chr 4:32,117,137...32,171,759

G

Sin3A associated protein 30

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SAP30 mRNA

NCBI chr16:37,758,494...37,763,825
Ensembl chr16:37,757,656...37,763,823

G

secretion associated, Ras related GTPase 1B

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of SAR1B mRNA]

NCBI chr10:36,525,365...36,555,009
Ensembl chr10:36,519,384...36,555,005

G

SAP domain containing ribonucleoprotein

affects methylation
decreases expression

ISO

Asbestos, Crocidolite affects the methylation of SARNP gene
Asbestos, Crocidolite results in decreased expression of SARNP mRNA

PMID:19446018 PMID:29279043 PMID:29523930

NCBI chr 7:1,835,597...1,889,833
Ensembl chr 7:1,835,597...1,897,295

G

SAM and SH3 domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SASH1 mRNA

NCBI chr 1:4,940,207...5,238,777
Ensembl chr 1:4,940,207...5,238,530

G

spermidine/spermine N1-acetyl transferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SAT1 mRNA

NCBI chr X:44,008,089...44,011,376
Ensembl chr X:44,006,781...44,011,374

G

spermidine/spermine N1-acetyltransferase family member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SAT2 mRNA

NCBI chr10:54,839,531...54,841,651
Ensembl chr10:54,839,189...54,841,958

G

SATB homeobox 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SATB1 mRNA

NCBI chr 9:4,916,958...5,010,359
Ensembl chr 9:4,917,215...4,989,925

G

SATB homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SATB2 promoter

NCBI chr 9:65,842,351...66,028,569
Ensembl chr 9:65,844,570...66,021,238

G

SAYSVFN motif domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SAYSD1 mRNA

NCBI chr15:4,273,302...4,278,971
Ensembl chr15:4,273,012...4,278,971

G

SET binding factor 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SBF1 gene

NCBI chr 7:122,237,968...122,264,591
Ensembl chr 7:122,237,968...122,264,531

G

SET binding factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SBF2 mRNA

NCBI chr 1:173,787,638...174,154,589
Ensembl chr 1:173,788,187...174,154,522

G

suprabasin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SBSN mRNA

NCBI chr 1:95,106,390...95,133,448
Ensembl chr 1:95,120,927...95,134,220

G

SR-related CTD-associated factor 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCAF11 mRNA

NCBI chr 7:129,450,872...129,503,280
Ensembl chr 7:129,417,955...129,503,280

G

SR-related CTD-associated factor 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCAF4 mRNA

NCBI chr11:42,951,254...43,007,293
Ensembl chr11:42,951,254...43,007,293

G

SCAN domain-containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SCAND1 mRNA

NCBI chr 3:165,278,723...165,279,587
Ensembl chr 3:165,278,723...165,279,587

G

SREBF chaperone

affects expression

ISO

Asbestos, Crocidolite affects the expression of SCAP mRNA

NCBI chr 8:119,184,366...119,239,086
Ensembl chr 8:119,184,438...119,239,075

G

scavenger receptor class A, member 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCARA5 mRNA

NCBI chr15:44,055,576...44,160,593
Ensembl chr15:44,055,630...44,160,585

G

scavenger receptor class B, member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCARB2 mRNA

NCBI chr14:15,842,583...15,894,123
Ensembl chr14:15,842,515...15,896,671

G

sciellin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCEL mRNA

NCBI chr15:86,754,595...86,871,200
Ensembl chr15:86,754,373...86,871,195

G

secretogranin II

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCG2 mRNA

NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:88,251,354...88,269,598

G

secretoglobin family 1A member 1

multiple interactions

ISO

MAP2K1 protein affects the reaction [Asbestos, Crocidolite results in increased expression of SCGB1A1 mRNA]

NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686

G

schwannomin interacting protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCHIP1 mRNA

NCBI chr 2:154,437,217...155,198,560
Ensembl chr 2:155,060,798...155,198,557

G

sodium voltage-gated channel beta subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCN1B mRNA

NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:95,481,298...95,491,197

G

sodium voltage-gated channel alpha subunit 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SCN5A mRNA

NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:128,098,613...128,196,470

G

sodium channel epithelial 1 subunit alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCNN1A mRNA

NCBI chr 4:159,809,187...159,832,409
Ensembl chr 4:159,809,170...159,832,405

G

sodium channel epithelial 1 subunit gamma

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCNN1G mRNA

NCBI chr 1:185,736,225...185,770,099
Ensembl chr 1:185,736,191...185,770,097

G

SCY1 like pseudokinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SCYL2 mRNA

NCBI chr 7:25,951,734...26,004,663
Ensembl chr 7:25,945,258...26,004,631

G

SDA1 domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SDAD1 mRNA

NCBI chr14:16,025,726...16,052,565
Ensembl chr14:16,025,727...16,055,359

G

succinate dehydrogenase complex iron sulfur subunit B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SDHB mRNA

NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667

G

SEC14-like lipid binding 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SEC14L1 mRNA

NCBI chr10:102,818,693...102,865,841
Ensembl chr10:102,818,693...102,865,839

G

SEC14-like lipid binding 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SEC14L2 mRNA

NCBI chr14:83,197,384...83,222,059
Ensembl chr14:83,197,387...83,217,317

G

SEC24 homolog A, COPII coat complex component

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SEC24A mRNA

NCBI chr10:36,450,043...36,525,303
Ensembl chr10:36,450,043...36,525,303

G

selenoprotein P

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SELENOP mRNA

NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:54,225,152...54,236,019

G

SEM1 26S proteasome subunit

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SEM1 mRNA

NCBI chr 4:35,638,306...35,658,462
Ensembl chr 4:35,638,306...35,658,462

G

semaphorin 3A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SEMA3A mRNA

NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:22,245,322...22,535,774

G

semaphorin 3E

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SEMA3E mRNA

NCBI chr 4:21,252,686...21,510,449
Ensembl chr 4:21,210,734...21,510,374

G

semaphorin 3F

affects expression

ISO

Asbestos, Crocidolite affects the expression of SEMA3F mRNA

NCBI chr 8:117,236,269...117,265,206
Ensembl chr 8:117,236,269...117,265,206

G

semaphorin 4G

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SEMA4G mRNA

NCBI chr 1:253,799,552...253,814,504
Ensembl chr 1:253,800,099...253,814,503

G

SUMO specific peptidase 3

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of SENP3 3' UTR

NCBI chr10:54,889,445...54,898,359
Ensembl chr10:54,888,847...54,898,227

G

SUMO specific peptidase 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SENP5 mRNA

NCBI chr11:82,289,680...82,324,545
Ensembl chr11:82,289,648...82,324,542

G

SUMO specific peptidase 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SENP6 mRNA

NCBI chr 8:89,868,115...89,951,803
Ensembl chr 8:89,868,867...89,948,062

G

SUMO specific peptidase 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SENP7 mRNA

NCBI chr11:57,892,801...58,053,213
Ensembl chr11:57,787,914...58,033,766

G

serine active site containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SERAC1 mRNA

NCBI chr 1:49,025,845...49,061,853
Ensembl chr 1:49,025,845...49,061,853

G

serpin family A member 3N

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SERPINA3N mRNA

NCBI chr 6:129,088,392...129,095,950
Ensembl chr 6:129,088,398...129,097,415

G

serpin family B member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SERPINB2 mRNA

NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031

G

serpin family E member 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SERPINE1 mRNA; Asbestos, Crocidolite results in increased expression of SERPINE1 protein
Asbestos, Crocidolite results in decreased expression of SERPINE1 mRNA

PMID:17975199 PMID:18687144 PMID:23917077 PMID:29553831

NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357

G

serpin family E member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SERPINE2 mRNA

NCBI chr 9:88,573,138...88,637,252
Ensembl chr 9:88,573,149...88,637,202

G

SERTA domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SERTAD1 mRNA

NCBI chr 1:91,903,297...91,906,565
Ensembl chr 1:91,891,814...91,907,001

G

SERTA domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SERTAD2 mRNA

NCBI chr14:98,935,428...99,039,536
Ensembl chr14:98,934,769...99,041,468

G

Set nuclear proto-oncogene

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SET mRNA

NCBI chr 3:33,732,319...33,743,433

G

SET domain containing 1B, histone lysine methyltransferase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SETD1B mRNA

NCBI chr12:39,056,809...39,082,399
Ensembl chr12:39,058,262...39,082,566

G

SET domain containing 2, histone lysine methyltransferase

decreases expression
multiple interactions
affects response to substance

ISO

Asbestos, Crocidolite results in decreased expression of SETD2 mRNA
SETD2 protein affects the reaction [Asbestos, Crocidolite results in decreased expression of CADM1 mRNA]; SETD2 protein affects the reaction [Asbestos, Crocidolite results in decreased expression of THBS2 mRNA]; SETD2 protein affects the reaction [Asbestos, Crocidolite results in increased expression of CLDN11 mRNA]
SETD2 protein affects the susceptibility to Asbestos, Crocidolite

PMID:29279043 PMID:37147272

NCBI chr 8:119,390,207...119,475,863
Ensembl chr 8:119,390,207...119,475,863

G

SET domain containing 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SETD4 mRNA

NCBI chr11:46,315,340...46,344,024
Ensembl chr11:46,323,895...46,344,024

G

SET domain containing 6, protein lysine methyltransferase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SETD6 mRNA

NCBI chr19:9,349,011...9,356,515
Ensembl chr19:9,353,520...9,356,515

G

SET domain bifurcated histone lysine methyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SETDB1 mRNA

NCBI chr 2:185,587,722...185,619,084
Ensembl chr 2:185,587,722...185,618,982

G

senataxin

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SETX mRNA
Asbestos, Crocidolite results in decreased expression of SETX mRNA

PMID:18687144 PMID:29523930

NCBI chr 3:32,825,771...32,878,740
Ensembl chr 3:32,828,412...32,878,740

G

stratifin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SFN protein

NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:151,110,530...151,111,995

G

splicing factor proline and glutamine rich

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SFPQ mRNA

NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:144,622,476...144,637,926

G

surfactant protein C

multiple interactions

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in decreased expression of SFTPC mRNA]

NCBI chr15:52,006,274...52,009,324
Ensembl chr15:52,006,283...52,009,475

G

sarcoglycan, delta

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of SGCD gene

NCBI chr10:31,847,713...32,829,554
Ensembl chr10:31,781,748...32,419,064

G

sarcoglycan, epsilon

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SGCE mRNA

NCBI chr 4:33,738,066...33,808,907
Ensembl chr 4:33,737,814...33,808,908

G

SH3GL interacting endocytic adaptor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SGIP1 mRNA

NCBI chr 5:122,755,216...122,963,677
Ensembl chr 5:122,765,890...122,963,659

G

serum/glucocorticoid regulated kinase 1

decreases methylation
increases expression

ISO

Asbestos, Crocidolite results in decreased methylation of SGK1 promoter
Asbestos, Crocidolite results in increased expression of SGK1 mRNA

PMID:18687144 PMID:29626692

NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231

G

sphingomyelin synthase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SGMS1 mRNA

NCBI chr 1:239,409,991...239,681,195
Ensembl chr 1:239,409,991...239,505,774

G

sphingomyelin synthase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SGMS2 mRNA

NCBI chr 2:222,567,661...222,641,804
Ensembl chr 2:222,567,664...222,590,807

G

SH2 domain containing 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SH2D5 mRNA

NCBI chr 5:155,753,087...155,763,936
Ensembl chr 5:155,750,803...155,763,936

G

SH3 domain binding glutamate-rich protein like 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SH3BGRL3 mRNA

NCBI chr 5:151,637,897...151,639,270
Ensembl chr 5:151,637,674...151,639,395

G

SH3-domain binding protein 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SH3BP4 5' UTR

NCBI chr 9:97,107,877...97,186,878
Ensembl chr 9:97,107,877...97,186,878

G

SH3 domain-containing kinase-binding protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SH3KBP1 mRNA

NCBI chr X:38,686,530...39,031,658
Ensembl chr X:38,686,530...39,031,393

G

SH3 and multiple ankyrin repeat domains 3

decreases methylation
increases expression

ISO

Asbestos, Crocidolite results in decreased methylation of SHANK3 3' UTR
Asbestos, Crocidolite results in increased expression of SHANK3 mRNA

PMID:29279043 PMID:29523930

NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:122,448,323...122,510,410

G

SH2 domain containing adaptor protein B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SHB mRNA

NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072

G

SHC adaptor protein 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of SHC1 mRNA
Asbestos, Crocidolite results in increased expression of SHC1 mRNA

PMID:17331233 PMID:29523930

NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:177,135,659...177,147,914

G

shieldin complex subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SHLD2 mRNA

NCBI chr16:9,554,921...9,646,186
Ensembl chr16:9,553,854...9,588,510

G

SHOC2 leucine-rich repeat scaffold protein

affects expression
increases expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of SHOC2 mRNA
Asbestos, Crocidolite results in increased expression of SHOC2 mRNA
Asbestos, Crocidolite results in decreased expression of SHOC2 mRNA

PMID:17331233 PMID:19446018 PMID:29279043

NCBI chr 1:262,964,345...263,052,898
Ensembl chr 1:262,965,011...263,052,634

G

shroom family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SHROOM2 mRNA

NCBI chr X:25,308,163...25,480,194
Ensembl chr X:25,308,163...25,479,385

G

salt-inducible kinase 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of SIK1 mRNA

NCBI chr20:9,947,104...9,958,729
Ensembl chr20:9,947,105...9,958,698

G

SIK family kinase 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SIK3 mRNA

NCBI chr 8:55,208,969...55,419,138
Ensembl chr 8:55,208,815...55,419,138

G

SIN3 transcription regulator family member A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SIN3A mRNA

NCBI chr 8:66,377,471...66,432,150
Ensembl chr 8:66,381,657...66,434,542

G

sirtuin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SIRT1 mRNA

NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000

G

SIVA1, apoptosis-inducing factor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SIVA1 mRNA

NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:137,526,031...137,530,790

G

spindle and kinetochore associated complex subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SKA2 mRNA

NCBI chr10:72,418,707...72,436,721
Ensembl chr10:72,418,617...72,436,718

G

SKI8 subunit of superkiller complex

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SKIC8 mRNA

NCBI chr 8:63,999,669...64,016,959
Ensembl chr 8:63,999,671...64,016,846

G

SKI/DACH domain containing 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of SKIDA1 5' UTR

NCBI chr17:85,706,693...85,717,499
Ensembl chr17:85,707,366...85,716,576

G

SKI-like proto-oncogene

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SKIL mRNA

NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:114,175,534...114,201,974

G

SLAIN motif family, member 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of SLAIN1 gene

NCBI chr15:86,897,476...86,957,113
Ensembl chr15:86,897,476...86,957,113

G

SLAM family member 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLAMF7 mRNA

NCBI chr13:86,668,060...86,688,222
Ensembl chr13:86,668,060...86,686,341

G

solute carrier family 11 member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC11A2 mRNA; Asbestos, Crocidolite results in increased expression of SLC11A2 protein

NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:133,381,878...133,418,941

G

solute carrier family 12, member 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC12A6 mRNA

NCBI chr 3:119,525,521...119,624,655
Ensembl chr 3:119,526,295...119,624,653

G

solute carrier family 15 member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC15A2 mRNA

NCBI chr11:77,519,565...77,548,609
Ensembl chr11:77,519,529...77,548,606

G

solute carrier family 16, member 11

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC16A11 mRNA

NCBI chr10:55,427,773...55,431,678
Ensembl chr10:55,427,903...55,431,678

G

solute carrier family 16 member 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC16A5 mRNA

NCBI chr10:101,206,371...101,220,300
Ensembl chr10:101,206,398...101,220,300

G

solute carrier family 16 member 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC16A7 mRNA

NCBI chr 7:62,929,067...63,096,995
Ensembl chr 7:62,936,567...63,040,386

G

solute carrier family 19 member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC19A2 mRNA

NCBI chr13:79,135,118...79,149,316
Ensembl chr13:79,135,059...79,149,315

G

solute carrier family 1 member 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC1A3 mRNA

NCBI chr 2:59,482,707...59,557,808
Ensembl chr 2:59,482,709...59,557,808

G

solute carrier family 1 member 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC1A4 mRNA

NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790

G

solute carrier family 1 member 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC1A5 mRNA

NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054

G

solute carrier family 25 member 17

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC25A17 mRNA

NCBI chr 7:114,724,533...114,767,163
Ensembl chr 7:114,724,533...114,767,345

G

solute carrier family 25 member 23

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC25A23 mRNA

NCBI chr 9:1,969,633...1,985,365
Ensembl chr 9:1,969,357...1,985,365

G

solute carrier family 25 member 24

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC25A24 mRNA

NCBI chr 2:199,449,425...199,487,287
Ensembl chr 2:199,449,345...199,487,290

G

solute carrier family 25, member 30

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC25A30 mRNA

NCBI chr15:57,486,346...57,508,981
Ensembl chr15:57,486,350...57,502,690

G

solute carrier family 25 member 37

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of SLC25A37 mRNA
Asbestos, Crocidolite results in decreased expression of SLC25A37 mRNA

PMID:24160326 PMID:29279043 PMID:29523930

NCBI chr15:50,944,085...50,986,506
Ensembl chr15:50,946,236...50,986,808

G

solute carrier family 25 member 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC25A4 mRNA

NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700

G

solute carrier family 25 member 5, pseudogene 11

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC25A6 mRNA

NCBI chr18:70,846,358...70,847,597
Ensembl chr18:70,846,358...70,847,597

G

solute carrier family 25, member 51

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC25A51 mRNA

NCBI chr 5:64,445,610...64,459,172
Ensembl chr 5:64,443,616...64,459,462

G

solute carrier family 27 member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC27A2 mRNA

NCBI chr 3:134,258,101...134,295,581
Ensembl chr 3:134,258,101...134,295,581

G

solute carrier family 29 member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC29A3 mRNA

NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299

G

solute carrier family 2 member 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC2A3 mRNA

NCBI chr 4:157,632,887...157,698,034
Ensembl chr 4:157,632,887...157,646,186

G

solute carrier family 31 member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC31A2 mRNA

NCBI chr 5:80,753,589...80,764,126
Ensembl chr 5:80,753,618...80,764,123

G

solute carrier family 35 member A2

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC35A2 mRNA
Asbestos, Crocidolite results in decreased expression of SLC35A2 mRNA

PMID:29279043 PMID:29523930

NCBI chr X:17,280,072...17,288,928
Ensembl chr X:17,280,074...17,288,613

G

solute carrier family 35, member A5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC35A5 mRNA

NCBI chr11:69,159,435...69,180,503
Ensembl chr11:69,159,384...69,180,502

G

solute carrier family 35 member B3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC35B3 mRNA

NCBI chr17:26,052,249...26,078,686
Ensembl chr17:26,052,232...26,079,505

G

solute carrier family 35, member E1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC35E1 mRNA

NCBI chr16:17,384,980...17,398,227
Ensembl chr16:17,385,030...17,397,310

G

solute carrier family 35, member E2B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC35E2 mRNA

NCBI chr 5:171,465,222...171,493,317
Ensembl chr 5:171,475,386...171,493,315

G

solute carrier family 35, member F5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC35F5 mRNA

NCBI chr13:39,544,253...39,581,210
Ensembl chr13:39,544,757...39,581,223

G

solute carrier family 36 member 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SLC36A4 gene

NCBI chr 8:20,801,256...20,834,046
Ensembl chr 8:20,801,289...20,834,044

G

solute carrier family 38, member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC38A1 mRNA

NCBI chr 7:129,612,414...129,681,727
Ensembl chr 7:129,617,387...129,681,778

G

solute carrier family 38, member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC38A2 mRNA

PMID:29279043 PMID:29523930

NCBI chr 7:129,730,450...129,742,619
Ensembl chr 7:129,730,450...129,742,619

G

solute carrier family 39, member 11

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SLC39A11 gene

NCBI chr10:98,775,155...99,196,302
Ensembl chr10:98,776,525...99,107,368

G

solute carrier family 39 member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC39A2 mRNA

NCBI chr15:27,063,699...27,066,349
Ensembl chr15:27,064,237...27,066,349

G

solute carrier family 3 member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC3A2 mRNA

NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064

G

solute carrier family 40 member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC40A1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460

G

solute carrier family 4 member 7

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC4A7 mRNA

NCBI chr15:13,015,854...13,095,485
Ensembl chr15:13,015,854...13,095,292

G

solute carrier family 5 member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC5A1 mRNA

NCBI chr14:81,778,495...81,843,084
Ensembl chr14:81,778,348...81,846,624

G

solute carrier family 6 member 13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC6A13 mRNA

NCBI chr 4:156,211,381...156,248,491
Ensembl chr 4:156,211,462...156,248,489

G

solute carrier family 6 member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC6A2 mRNA

NCBI chr19:30,183,289...30,228,292
Ensembl chr19:30,183,383...30,223,348

G

solute carrier family 6 member 3

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SLC6A3 gene

NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:31,537,990...31,578,962

G

solute carrier family 6 member 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLC6A6 mRNA

NCBI chr 4:125,752,340...125,826,033
Ensembl chr 4:125,752,372...125,826,032

G

solute carrier family 7 member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC7A1 mRNA

NCBI chr12:11,664,488...11,740,030
Ensembl chr12:11,664,399...11,740,030

G

solute carrier family 7 member 11

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC7A11 mRNA

NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695

G

solute carrier family 7 member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC7A2 mRNA

PMID:24160326 PMID:25757056

NCBI chr16:58,115,991...58,174,256
Ensembl chr16:58,120,968...58,174,256

G

solute carrier family 7 member 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLC7A5 mRNA

NCBI chr19:66,843,808...66,872,412
Ensembl chr19:66,843,808...66,872,412

G

solute carrier family 7 member 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC7A6 mRNA

NCBI chr19:50,982,459...51,010,140
Ensembl chr19:50,984,132...51,010,134

G

solute carrier family 9 member A6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLC9A6 mRNA

NCBI chr X:139,468,045...139,524,111
Ensembl chr X:139,458,127...139,524,109

G

solute carrier organic anion transporter family, member 3a1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLCO3A1 mRNA

NCBI chr 1:137,516,037...137,797,836
Ensembl chr 1:137,505,158...137,797,836

G

solute carrier organic anion transporter family, member 4a1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLCO4A1 mRNA

NCBI chr 3:187,936,735...187,955,873
Ensembl chr 3:187,936,820...187,955,871

G

solute carrier organic anion transporter family, member 5A1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLCO5A1 mRNA

NCBI chr 5:11,012,001...11,141,180
Ensembl chr 5:11,012,075...11,141,177

G

SMC5-SMC6 complex localization factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLF2 mRNA

NCBI chr 1:253,731,979...253,794,577
Ensembl chr 1:253,732,025...253,794,577

G

SRA stem-loop interacting RNA binding protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLIRP mRNA

NCBI chr 6:112,819,684...112,828,715
Ensembl chr 6:112,819,448...112,828,715

G

slit guidance ligand 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SLIT2 mRNA

NCBI chr14:66,829,661...67,168,517
Ensembl chr14:66,829,661...67,167,146

G

SLIT and NTRK-like family, member 3

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of SLITRK3 5' UTR

NCBI chr 2:159,983,650...159,996,194
Ensembl chr 2:159,973,029...159,996,342

G

STE20-like kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLK mRNA

NCBI chr 1:256,415,013...256,470,942
Ensembl chr 1:256,415,013...256,467,829

G

sarcolemma associated protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLMAP mRNA

NCBI chr16:1,673,964...1,791,902
Ensembl chr16:1,673,964...1,791,902

G

secretory leukocyte peptidase inhibitor

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of SLPI mRNA
Asbestos, Crocidolite results in increased expression of SLPI mRNA

PMID:23917077 PMID:24160326

NCBI chr 3:173,501,573...173,503,822
Ensembl chr 3:173,501,573...173,503,822

G

secreted Ly6/Plaur domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SLURP1 mRNA

NCBI chr 7:108,500,933...108,502,349
Ensembl chr 7:108,500,933...108,502,349

G

SMAD family member 1

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of SMAD1 protein

NCBI chr19:45,417,430...45,477,962
Ensembl chr19:45,417,433...45,477,957

G

SMAD family member 2

affects expression
increases phosphorylation

ISO

Asbestos, Crocidolite affects the expression of SMAD2 mRNA
Asbestos, Crocidolite results in increased phosphorylation of SMAD2 protein

PMID:17331233 PMID:17975199

NCBI chr18:72,124,792...72,193,345
Ensembl chr18:72,124,863...72,187,388

G

SMAD family member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMAD3 mRNA

NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:73,024,760...73,132,324

G

SMAD family member 5

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of SMAD5 protein

NCBI chr17:7,867,640...7,896,983
Ensembl chr17:7,871,984...7,890,992

G

SMAD family member 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMAD6 mRNA

NCBI chr 8:73,345,457...73,414,985
Ensembl chr 8:73,345,460...73,414,149

G

SMAD family member 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMAD7 mRNA

NCBI chr18:71,263,508...71,291,849
Ensembl chr18:71,263,508...71,291,849

G

SMAD family member 9

decreases phosphorylation

ISO

Asbestos, Crocidolite results in decreased phosphorylation of SMAD9 protein

NCBI chr 2:141,106,668...141,156,477
Ensembl chr 2:141,106,668...141,156,477

G

SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMARCA4 mRNA

NCBI chr 8:28,438,370...28,535,071
Ensembl chr 8:28,443,810...28,535,070

G

SNF2 related chromatin remodeling ATPase with DExD box 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMARCAD1 mRNA

NCBI chr 4:95,639,722...95,709,055
Ensembl chr 4:95,641,295...95,702,414

G

SWI/SNF related BAF chromatin remodeling complex subunit C2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SMARCC2 mRNA

NCBI chr 7:1,466,223...1,494,627
Ensembl chr 7:1,466,454...1,494,626

G

SWI/SNF related BAF chromatin remodeling complex subunit D3

affects expression

ISO

Asbestos, Crocidolite affects the expression of SMARCD3 mRNA

NCBI chr 4:11,441,142...11,472,781
Ensembl chr 4:11,441,157...11,472,781

G

structural maintenance of chromosomes 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMC5 mRNA

NCBI chr 1:230,195,894...230,265,677
Ensembl chr 1:230,195,894...230,265,621

G

small integral membrane protein 1 (Vel blood group)

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SMIM1 mRNA

NCBI chr 5:169,861,751...169,867,070
Ensembl chr 5:169,864,251...169,866,942

G

small integral membrane protein 14

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMIM14 mRNA

NCBI chr14:43,136,754...43,180,622
Ensembl chr14:43,136,867...43,183,416

G

small integral membrane protein 27

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMIM27 mRNA

NCBI chr 5:60,195,679...60,196,346
Ensembl chr 5:60,195,679...60,196,346

G

small integral membrane protein 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of SMIM3 mRNA

NCBI chr18:56,200,458...56,252,778
Ensembl chr18:56,200,459...56,227,379

G

small integral membrane protein 7

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMIM7 mRNA

NCBI chr16:17,308,466...17,312,384
Ensembl chr16:17,308,395...17,312,371

G

survival motor neuron domain containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMNDC1 mRNA

NCBI chr 1:262,395,034...262,406,104
Ensembl chr 1:262,386,590...262,405,707

G

spermine oxidase

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of SMOX mRNA
Asbestos, Crocidolite affects the expression of SMOX mRNA

PMID:18687144 PMID:24160326

NCBI chr 3:139,184,793...139,220,174
Ensembl chr 3:139,184,798...139,220,170
Ensembl chr X:139,184,798...139,220,170

G

smoothelin

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SMTN gene

NCBI chr14:82,622,223...82,644,525
Ensembl chr14:82,621,375...82,644,514

G

smoothelin-like 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SMTNL2 mRNA

NCBI chr10:57,506,873...57,528,050
Ensembl chr10:57,506,873...57,528,050

G

SMU1, DNA replication regulator and spliceosomal factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SMU1 mRNA

NCBI chr 5:60,652,680...60,671,251
Ensembl chr 5:60,652,680...60,671,251

G

SMAD specific E3 ubiquitin protein ligase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SMURF2 mRNA

NCBI chr10:92,261,516...92,362,185
Ensembl chr10:92,261,525...92,362,552

G

snail family transcriptional repressor 1

increases expression
affects expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SNAI1 protein
Asbestos, Crocidolite affects the expression of SNAI1 mRNA
Asbestos, Crocidolite results in decreased expression of SNAI1 mRNA

NCBI chr 3:176,667,476...176,671,965

G

snail family transcriptional repressor 2

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of SNAI2 protein
Asbestos, Crocidolite affects the expression of SNAI2 mRNA

NCBI chr11:99,686,934...99,690,349
Ensembl chr11:99,686,934...99,690,349

G

synaptosome associated protein 23

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNAP23 mRNA

NCBI chr 3:127,966,184...127,999,929
Ensembl chr 3:127,967,886...127,998,067

G

synaptosome associated protein 25

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNAP25 mRNA

PMID:18687144 PMID:23634900

NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:144,494,595...144,576,448

G

synaptosome associated protein 29

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNAP29 mRNA

NCBI chr11:97,082,721...97,113,195
Ensembl chr11:97,082,739...97,113,195

G

small nuclear RNA activating complex, polypeptide 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SNAPC1 mRNA

NCBI chr 6:98,420,588...98,442,065
Ensembl chr 6:98,420,340...98,442,489

G

small nuclear RNA activating complex, polypeptide 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNAPC3 mRNA

NCBI chr 5:102,863,867...102,890,573
Ensembl chr 5:102,863,854...102,893,499

G

small nucleolar RNA, C/D box 35A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNORD35A mRNA

NCBI chr 1:104,746,648...104,746,727
Ensembl chr 1:104,746,648...104,746,727

G

small nucleolar RNA, C/D box 61

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNORD61 mRNA

NCBI chr X:140,350,552...140,350,624
Ensembl chr X:140,350,552...140,350,624

G

small nucleolar RNA, C/D box 83B

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of SNORD83B 5' UTR

NCBI chr 7:113,503,235...113,503,328
Ensembl chr 7:113,503,235...113,503,328

G

small nucleolar RNA, C/D box 99

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNORD99 mRNA

NCBI chr 5:149,790,919...149,790,992
Ensembl chr 5:149,790,919...149,790,992

G

SNF related kinase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNRK mRNA

NCBI chr 8:130,657,204...130,711,461
Ensembl chr 8:130,657,266...130,711,457

G

small nuclear ribonucleoprotein U4/U6.U5 subunit 27

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNRNP27 mRNA

NCBI chr 4:120,681,054...120,691,343
Ensembl chr 4:120,679,255...120,690,656

G

small nuclear ribonucleoprotein U11/U12 subunit 35

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SNRNP35 mRNA

NCBI chr12:37,773,052...37,781,635
Ensembl chr12:37,771,759...37,783,908

G

sorting nexin 24

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SNX24 mRNA

NCBI chr18:48,869,804...49,024,352
Ensembl chr18:48,869,882...49,024,350

G

sorting nexin 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SNX5 mRNA

NCBI chr 3:152,075,258...152,094,508
Ensembl chr 3:152,075,258...152,094,877

G

sorting nexin 9

affects expression

ISO

Asbestos, Crocidolite affects the expression of SNX9 mRNA

NCBI chr 1:48,827,061...48,915,215
Ensembl chr 1:48,830,053...48,915,214

G

sterol O-acyltransferase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOAT2 mRNA

NCBI chr 7:135,160,424...135,173,521
Ensembl chr 7:135,160,402...135,173,513

G

suppressor of cytokine signaling 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOCS2 mRNA

NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:31,874,463...31,930,423

G

suppressor of cytokine signaling 3

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SOCS3 mRNA
Asbestos, Crocidolite results in decreased expression of SOCS3 mRNA

PMID:18687144 PMID:25757056

NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,690,976...103,704,825

G

suppressor of cytokine signaling 5

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SOCS5 mRNA

NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883

G

superoxide dismutase 1

multiple interactions
increases expression
decreases activity

ISO
EXP

SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of TNF protein]
Asbestos, Crocidolite results in increased expression of SOD1 mRNA
Asbestos, Crocidolite results in decreased activity of SOD1 protein
SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of EGFR protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]; SOD1 protein inhibits the reaction [Asbestos, Crocidolite results in increased uptake of Iron]; SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased phosphorylation of and results in increased activity of MAPK14 protein]; SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]

PMID:1316905 PMID:8025751 PMID:14962975 PMID:16272461 PMID:16601788 More...

NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399

G

superoxide dismutase 2

increases expression
decreases response to substance
decreases expression
affects expression

EXP
ISO

Asbestos, Crocidolite results in increased expression of SOD2 mRNA; Asbestos, Crocidolite results in increased expression of SOD2 protein
SOD2 protein results in decreased susceptibility to Asbestos, Crocidolite
Asbestos, Crocidolite results in decreased expression of SOD2 mRNA
Asbestos, Crocidolite affects the expression of SOD2 mRNA

PMID:1316905 PMID:8025751 PMID:8118652 PMID:8818626 PMID:9111221 More...

NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168

G

superoxide dismutase 3

affects response to substance
multiple interactions

ISO

SOD3 protein affects the susceptibility to Asbestos, Crocidolite
Asbestos, Crocidolite affects the expression of and affects the activity of SOD3 protein

PMID:15298984 PMID:18165226

NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125

G

SON DNA and RNA binding protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SON mRNA

NCBI chr11:44,336,818...44,409,127
Ensembl chr11:44,377,976...44,409,127

G

sorbin and SH3 domain containing 1

affects methylation
decreases expression

ISO

Asbestos, Crocidolite affects the methylation of SORBS1 5' UTR
Asbestos, Crocidolite results in decreased expression of SORBS1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:249,057,324...249,279,703
Ensembl chr 1:249,057,324...249,279,608

G

SOS Ras/Rac guanine nucleotide exchange factor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of SOS1 mRNA

NCBI chr 6:20,286,117...20,363,350
Ensembl chr 6:20,286,117...20,363,350

G

SRY-box transcription factor 10

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOX10 mRNA

NCBI chr 7:112,605,721...112,615,097
Ensembl chr 7:112,605,721...112,615,990

G

SRY-box transcription factor 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOX3 mRNA

NCBI chr X:144,344,892...144,346,971
Ensembl chr X:144,344,892...144,346,987

G

SRY-box transcription factor 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOX4 mRNA

NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024

G

SRY-box transcription factor 5

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of SOX5 5' UTR

NCBI chr 4:178,512,272...179,467,686
Ensembl chr 4:178,512,272...178,938,495

G

SRY-box transcription factor 9

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SOX9 mRNA

NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250

G

Sp1 transcription factor

affects expression

ISO

Asbestos, Crocidolite affects the expression of SP1 mRNA

NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513

G

Sp3 transcription factor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SP3 mRNA

NCBI chr 3:78,219,421...78,272,318
Ensembl chr 3:78,219,426...78,264,517

G

sperm associated antigen 9

increases expression
decreases methylation

ISO

Asbestos, Crocidolite results in increased expression of SPAG9 mRNA
Asbestos, Crocidolite results in decreased methylation of SPAG9 3' UTR

PMID:18687144 PMID:29523930

NCBI chr10:79,440,311...79,574,709
Ensembl chr10:79,440,377...79,575,258

G

secreted protein acidic and cysteine rich

multiple interactions
decreases expression
increases response to substance

ISO

Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in decreased expression of SFTPC mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of ABHD2 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of GUCY2E mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of HCN2 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of ITSN1 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of KBTBD11 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of MAPKAPK5 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of MORF4L1 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of RECQL mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of SAA3 mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of SAR1B mRNA]; Asbestos, Crocidolite inhibits the reaction [SPARC gene mutant form results in increased expression of ZNHIT2 mRNA]
Asbestos, Crocidolite results in decreased expression of SPARC mRNA
SPARC protein results in increased susceptibility to Asbestos, Crocidolite

PMID:19446018 PMID:28056339 PMID:29279043

NCBI chr10:40,017,065...40,038,816
Ensembl chr10:40,017,075...40,039,268

G

spastin

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of SPAST gene

NCBI chr 6:26,807,220...26,858,456
Ensembl chr 6:26,807,220...26,858,446

G

spermatogenesis associated 25

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPATA25 mRNA

NCBI chr 3:173,981,863...173,983,818
Ensembl chr 3:173,981,866...173,983,818

G

spermatogenesis associated 32

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPATA32 mRNA

NCBI chr10:88,653,309...88,664,455
Ensembl chr10:88,642,470...88,664,543

G

spermatogenesis associated 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPATA6 mRNA

PMID:25351596 PMID:29279043

NCBI chr 5:131,821,585...131,905,011
Ensembl chr 5:131,821,585...131,905,014

G

sperm flagellar 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPEF2 mRNA

NCBI chr 2:60,239,655...60,421,850
Ensembl chr 2:60,239,655...60,421,850

G

spen family transcriptional repressor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPEN mRNA

NCBI chr 5:159,058,258...159,131,789
Ensembl chr 5:159,058,258...159,165,934

G

SPG21 abhydrolase domain containing, maspardin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPG21 mRNA

NCBI chr 8:74,876,136...74,903,676
Ensembl chr 8:74,876,136...74,903,676

G

sphingosine kinase 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of SPHK1 mRNA
Asbestos, Crocidolite affects the expression of SPHK1 mRNA

PMID:18687144 PMID:25757056

NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082

G

Spi-1 proto-oncogene

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPI1 protein
Asbestos, Crocidolite results in increased expression of SPI1 mRNA

NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540

G

spindlin family, member 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPIN4 mRNA

NCBI chr X:63,898,338...63,902,427
Ensembl chr X:63,900,148...63,903,811

G

serine peptidase inhibitor, Kazal type 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPINK1 mRNA

NCBI chr18:36,121,626...36,133,596
Ensembl chr18:36,076,399...36,133,545

G

spire-type actin nucleation factor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPIRE1 mRNA

NCBI chr18:63,311,800...63,441,545
Ensembl chr18:63,311,800...63,441,534

G

spire-type actin nucleation factor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPIRE2 mRNA

NCBI chr19:68,281,878...68,320,427
Ensembl chr19:68,281,870...68,320,427

G

SPOUT domain containing methyltransferase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPOUT1 mRNA

NCBI chr 3:33,849,007...33,856,564
Ensembl chr 3:33,849,007...33,856,269

G

secreted phosphoprotein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPP1 protein
Asbestos, Crocidolite results in increased expression of SPP1 mRNA

PMID:21570478 PMID:23917077 PMID:29507420

NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820

G

signal peptide peptidase-like 2A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPPL2A mRNA

NCBI chr 3:134,602,684...134,646,752
Ensembl chr 3:134,605,750...134,646,752

G

sprouty-related, EVH1 domain containing 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of SPRED1 mRNA

NCBI chr 3:124,437,230...124,504,358
Ensembl chr 3:124,437,230...124,504,358

G

sprouty-related, EVH1 domain containing 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of SPRED2 mRNA

NCBI chr14:98,350,577...98,452,143
Ensembl chr14:98,350,290...98,452,143

G

sprouty RTK signaling antagonist 2

increases expression
increases methylation
affects expression

ISO

Asbestos, Crocidolite results in increased expression of SPRY2 mRNA
Asbestos, Crocidolite results in increased methylation of SPRY2 gene
Asbestos, Crocidolite affects the expression of SPRY2 mRNA

PMID:18687144 PMID:25757056 PMID:29523930

NCBI chr15:89,106,809...89,111,926
Ensembl chr15:89,103,731...89,115,074

G

sprouty RTK signaling antagonist 4

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of SPRY4 mRNA
Asbestos, Crocidolite results in increased expression of SPRY4 mRNA

PMID:18687144 PMID:25351596 PMID:25757056

NCBI chr18:30,687,633...30,702,546
Ensembl chr18:30,687,039...30,704,173

G

spectrin, beta, non-erythrocytic 4

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SPTBN4 mRNA

NCBI chr 1:91,778,379...91,865,970
Ensembl chr 1:91,778,380...91,865,049

G

serine palmitoyltransferase, long chain base subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SPTLC1 mRNA

NCBI chr17:12,029,189...12,068,234
Ensembl chr17:12,029,189...12,068,234

G

sequestosome 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of SQSTM1 mRNA
Asbestos, Crocidolite results in increased expression of SQSTM1 mRNA

PMID:17331233 PMID:18687144 PMID:25757056

NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750

G

steroid receptor RNA activator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRA1 mRNA

NCBI chr18:28,543,347...28,547,474
Ensembl chr18:28,543,348...28,546,575

G

SRC proto-oncogene, non-receptor tyrosine kinase

increases expression
multiple interactions
increases phosphorylation

ISO

Asbestos, Crocidolite results in increased expression of SRC mRNA
SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK1 protein]; SRC protein affects the reaction [Asbestos, Crocidolite results in increased phosphorylation of MAPK3 protein]
Asbestos, Crocidolite results in increased phosphorylation of SRC protein

PMID:14737115 PMID:23634900

NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462

G

steroid 5 alpha-reductase 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRD5A3 mRNA

NCBI chr14:32,400,603...32,414,987
Ensembl chr14:32,400,603...32,415,117

G

splicing regulatory glutamic acid and lysine rich protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SREK1 mRNA

NCBI chr 2:36,583,412...36,618,978
Ensembl chr 2:36,583,412...36,619,001

G

serglycin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SRGN mRNA

NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327

G

signal recognition particle 68

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SRP68 mRNA

NCBI chr10:101,980,089...102,006,913
Ensembl chr10:101,980,090...102,007,207

G

SRSF protein kinase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRPK1 mRNA

NCBI chr20:6,647,539...6,684,129
Ensembl chr20:6,649,450...6,683,835

G

SRSF protein kinase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRPK2 mRNA

NCBI chr 4:12,356,983...12,548,345
Ensembl chr 4:12,357,053...12,548,342

G

serine racemase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRR mRNA

NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100

G

serine/arginine repetitive matrix 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SRRM3 mRNA

NCBI chr12:26,445,718...26,515,185
Ensembl chr12:26,445,718...26,515,124

G

serine and arginine rich splicing factor 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRSF10 mRNA

NCBI chr 5:153,372,307...153,386,520
Ensembl chr 5:153,372,316...153,386,513

G

serine and arginine rich splicing factor 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRSF11 mRNA

NCBI chr 2:249,733,464...249,760,296
Ensembl chr 2:249,733,464...249,760,499

G

serine and arginine rich splicing factor 3

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SRSF3 mRNA
Asbestos, Crocidolite results in decreased expression of SRSF3 mRNA

PMID:29279043 PMID:29523930

NCBI chr20:7,093,529...7,103,517
Ensembl chr20:7,093,565...7,103,516

G

serine and arginine rich splicing factor 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SRSF6 mRNA

NCBI chr 3:172,009,072...172,014,395
Ensembl chr 3:172,009,061...172,014,392

G

SS18 subunit of BAF chromatin remodeling complex

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SS18 mRNA

NCBI chr18:6,047,619...6,169,151
Ensembl chr18:6,047,619...6,109,913

G

single stranded DNA binding protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSBP1 mRNA

NCBI chr 4:70,232,740...70,242,824
Ensembl chr 4:70,232,794...70,243,700

G

single stranded DNA binding protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSBP3 mRNA

NCBI chr 5:126,920,145...127,057,968
Ensembl chr 5:126,919,120...127,056,799

G

SS nuclear autoantigen 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SSNA1 mRNA

NCBI chr 3:28,483,107...28,484,571
Ensembl chr 3:28,483,107...28,484,608

G

signal sequence receptor subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSR2 mRNA

NCBI chr 2:176,346,117...176,354,868
Ensembl chr 2:176,346,404...176,355,781

G

somatostatin receptor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSTR2 mRNA

NCBI chr10:99,163,353...99,170,519
Ensembl chr10:99,162,740...99,183,863

G

SSU72 homolog, RNA polymerase II CTD phosphatase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSU72 mRNA

NCBI chr 5:171,595,919...171,625,675
Ensembl chr 5:171,595,851...171,625,268

G

SSX family member 2 interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SSX2IP mRNA

NCBI chr 2:237,958,286...237,991,026
Ensembl chr 2:237,958,465...237,991,017

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ST3GAL1 mRNA

NCBI chr 7:100,734,300...100,802,443
Ensembl chr 7:100,734,300...100,745,242

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of ST3GAL6 mRNA
Asbestos, Crocidolite results in decreased expression of ST3GAL6 mRNA

PMID:25351596 PMID:29279043

NCBI chr11:55,530,120...55,590,950
Ensembl chr11:55,530,248...55,598,720

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ST6GAL1 mRNA

NCBI chr11:91,031,481...91,158,111
Ensembl chr11:91,032,450...91,040,415

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of ST8SIA4 mRNA

NCBI chr 9:103,437,479...103,532,008
Ensembl chr 9:103,437,479...103,532,008

G

signal transducing adaptor molecule

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STAM mRNA

NCBI chr17:82,028,779...82,074,717
Ensembl chr17:82,028,703...82,075,013

G

StAR-related lipid transfer domain containing 13

increases expression
affects methylation

ISO

Asbestos, Crocidolite results in increased expression of STARD13 mRNA
Asbestos, Crocidolite affects the methylation of STARD13 5' UTR; Asbestos, Crocidolite affects the methylation of STARD13 gene

PMID:18687144 PMID:29523930

NCBI chr12:5,401,878...5,797,937
Ensembl chr12:5,401,995...5,794,967

G

StAR-related lipid transfer domain containing 5

affects expression

ISO

Asbestos, Crocidolite affects the expression of STARD5 mRNA

NCBI chr 1:147,015,304...147,025,170
Ensembl chr 1:147,015,299...147,026,351

G

signal transducer and activator of transcription 4

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STAT4 mRNA

NCBI chr 9:56,964,617...57,080,523
Ensembl chr 9:56,911,523...57,077,346

G

stanniocalcin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STC1 mRNA

NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082

G

stanniocalcin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STC2 mRNA

NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447

G

STEAP family member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STEAP1 mRNA

NCBI chr 4:29,231,809...29,242,317
Ensembl chr 4:29,231,753...29,242,317

G

STEAP4 metalloreductase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STEAP4 mRNA

PMID:23917077 PMID:24160326

NCBI chr 4:27,032,096...27,054,769
Ensembl chr 4:27,009,584...27,067,105

G

serine/threonine kinase 32C

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of STK32C gene

NCBI chr 1:203,330,325...203,411,325
Ensembl chr 1:203,330,325...203,411,325

G

stathmin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STMN1 mRNA

NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:151,964,351...151,970,842

G

stathmin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STMN2 mRNA

NCBI chr 2:95,112,017...95,159,642
Ensembl chr 2:95,112,019...95,159,335

G

stomatin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STOM mRNA

NCBI chr 3:39,042,503...39,064,818
Ensembl chr 3:39,042,503...39,064,818

G

striatin interacting protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STRIP2 mRNA

NCBI chr 4:59,503,478...59,545,745
Ensembl chr 4:59,503,481...59,545,739

G

striatin 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STRN3 mRNA

NCBI chr 6:74,783,156...74,869,473
Ensembl chr 6:74,783,156...74,869,473

G

syntaxin 16

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STX16 mRNA

NCBI chr 3:183,271,417...183,300,746
Ensembl chr 3:183,272,031...183,300,745

G

syntaxin 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STX1A mRNA

NCBI chr12:27,278,517...27,306,547
Ensembl chr12:27,278,517...27,306,471

G

syntaxin 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of STX3 mRNA

NCBI chr 1:217,940,697...218,114,865
Ensembl chr 1:217,909,169...218,110,466

G

serine/threonine/tyrosine interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of STYX mRNA

NCBI chr15:21,043,738...21,075,515

G

SUB1 regulator of transcription

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SUB1 mRNA

NCBI chr 2:62,735,379...62,747,545
Ensembl chr 2:62,732,736...62,747,679

G

succinate-CoA ligase GDP-forming subunit beta

affects expression

ISO

Asbestos, Crocidolite affects the expression of SUCLG2 mRNA

NCBI chr 4:129,623,833...129,893,937
Ensembl chr 4:129,623,834...129,937,296

G

SURP and G patch domain containing 2

decreases expression
increases expression

ISO

Asbestos, Crocidolite results in decreased expression of SUGP2 mRNA
Asbestos, Crocidolite results in increased expression of SUGP2 mRNA

PMID:29279043 PMID:29523930

NCBI chr16:19,193,910...19,225,364
Ensembl chr16:19,198,831...19,225,292

G

SGT1 homolog, MIS12 kinetochore complex assembly cochaperone

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SUGT1 mRNA

PMID:29279043 PMID:29523930

NCBI chr15:61,400,478...61,441,303
Ensembl chr15:61,400,004...61,468,852

G

sulfatase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SULF1 mRNA

NCBI chr 5:11,145,950...11,308,622
Ensembl chr 5:11,145,950...11,308,643

G

sulfotransferase family 1A member 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SULT1A1 mRNA

NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131

G

sulfotransferase family 1B member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SULT1B1 mRNA

NCBI chr14:20,771,917...20,784,665
Ensembl chr14:20,771,868...20,785,549

G

sulfotransferase family 2B member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SULT2B1 mRNA

NCBI chr 1:105,336,614...105,397,744
Ensembl chr 1:105,336,614...105,397,744

G

Sad1 and UNC84 domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SUN1 mRNA

PMID:18687144 PMID:29279043

NCBI chr12:20,510,230...20,555,123
Ensembl chr12:20,490,861...20,555,240

G

SPT20 homolog, SAGA complex component

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SUPT20 mRNA

NCBI chr 2:141,047,479...141,080,656
Ensembl chr 2:141,047,477...141,081,361

G

SPT3 homolog, SAGA and STAGA complex component

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SUPT3 mRNA

NCBI chr 9:23,375,889...23,704,229
Ensembl chr 9:23,376,136...23,704,466

G

SPT5 homolog, DSIF elongation factor subunit

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SUPT5 mRNA

NCBI chr 1:92,714,276...92,745,489
Ensembl chr 1:92,714,281...92,744,445

G

sushi domain containing 6

affects expression

ISO

Asbestos, Crocidolite affects the expression of SUSD6 mRNA

NCBI chr 6:106,130,183...106,262,900
Ensembl chr 6:106,169,118...106,262,900

G

synapse defective Rho GTPase homolog 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SYDE2 mRNA

NCBI chr 2:237,557,395...237,591,290
Ensembl chr 2:237,558,274...237,591,290

G

synapsin III

affects expression

ISO

Asbestos, Crocidolite affects the expression of SYN3 mRNA

NCBI chr 7:19,244,032...19,701,571
Ensembl chr 7:19,264,094...19,696,510

G

synaptotagmin binding, cytoplasmic RNA interacting protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SYNCRIP mRNA

NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:98,282,358...98,315,386

G

spectrin repeat containing nuclear envelope protein 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of SYNE1 mRNA
Asbestos, Crocidolite results in decreased expression of SYNE1 mRNA

PMID:18687144 PMID:29279043

NCBI chr 1:43,917,640...44,388,802
Ensembl chr 1:43,895,994...44,388,721

G

synaptojanin 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SYNJ1 mRNA

NCBI chr11:43,678,709...43,755,526
Ensembl chr11:43,678,709...43,755,526

G

synaptophysin-like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SYPL1 mRNA

NCBI chr 6:55,292,555...55,311,519
Ensembl chr 6:55,292,567...55,314,714

G

synaptophysin-like 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SYPL2 mRNA

NCBI chr 2:198,537,208...198,551,939
Ensembl chr 2:198,537,208...198,561,640

G

synaptotagmin 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SYT2 mRNA

NCBI chr13:48,639,634...48,749,814
Ensembl chr13:48,639,934...48,749,812

G

synaptotagmin 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of SYT5 mRNA

NCBI chr 1:78,320,034...78,327,750
Ensembl chr 1:78,320,034...78,327,746

G

synaptotagmin-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of SYTL2 mRNA

NCBI chr 1:153,685,403...153,791,758
Ensembl chr 1:153,665,327...153,791,756

G

transforming, acidic coiled-coil containing protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TACC2 mRNA

NCBI chr 1:194,546,428...194,758,152
Ensembl chr 1:194,569,650...194,758,152

G

tumor-associated calcium signal transducer 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TACSTD2 mRNA

NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:98,033,251...98,039,323

G

TATA-box binding protein associated factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TAF1 mRNA

NCBI chr X:70,680,901...70,756,535
Ensembl chr X:70,680,906...70,756,735

G

TATA-box binding protein associated factor, RNA polymerase I subunit B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TAF1B mRNA

NCBI chr 6:46,845,571...46,923,209
Ensembl chr 6:46,846,029...46,923,209

G

TATA-box binding protein associated factor 4b

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TAF4B mRNA

NCBI chr18:6,227,299...6,360,970
Ensembl chr18:6,227,345...6,356,275

G

TATA-box binding protein associated factor 8

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAF8 mRNA

NCBI chr 9:20,989,554...21,009,541
Ensembl chr 9:20,989,465...21,009,983

G

TATA-box binding protein associated factor 9b

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TAF9B mRNA

NCBI chr X:75,354,823...75,366,166
Ensembl chr X:75,354,825...75,366,414

G

transgelin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TAGLN mRNA

NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563

G

transaldolase 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TALDO1 mRNA

NCBI chr 1:205,923,196...205,933,526
Ensembl chr 1:205,923,165...205,933,535

G

transport and golgi organization 2 homolog

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TANGO2 mRNA

NCBI chr11:96,150,292...96,196,883
Ensembl chr11:96,150,266...96,196,881

G

TRAF family member-associated NFKB activator

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TANK mRNA

NCBI chr 3:66,522,834...66,598,864
Ensembl chr 3:66,537,175...66,598,864

G

TAO kinase 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of TAOK1 5' UTR

NCBI chr10:62,871,198...62,989,049
Ensembl chr10:62,871,198...62,957,595

G

taste 1 receptor member 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS1R1 mRNA

NCBI chr 5:167,816,566...167,829,136
Ensembl chr 5:167,816,569...167,828,489

G

taste 1 receptor member 2

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS1R2 mRNA

NCBI chr 5:157,192,799...157,208,937
Ensembl chr 5:157,192,799...157,208,937

G

taste receptor, type 2, member 108

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R4 mRNA

NCBI chr 4:70,254,367...70,255,281
Ensembl chr 4:70,254,367...70,255,281

G

taste receptor, type 2, member 116

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R14 mRNA

NCBI chr 4:167,998,392...167,999,366
Ensembl chr 4:167,998,392...167,999,366

G

taste receptor, type 2, member 118

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R16 mRNA

NCBI chr 4:53,414,815...53,415,714
Ensembl chr 4:53,414,815...53,415,714

G

taste receptor, type 2, member 119

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R1 mRNA

NCBI chr 2:84,948,489...84,949,496
Ensembl chr 2:84,948,489...84,949,496

G

taste receptor, type 2, member 121

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R13 mRNA

NCBI chr 4:167,718,831...167,719,748

G

taste receptor, type 2, member 126

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R41 mRNA

NCBI chr 4:72,300,448...72,301,374
Ensembl chr 4:72,300,448...72,301,374

G

taste receptor, type 2, member 130

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R7 mRNA

NCBI chr 4:167,004,245...167,005,183
Ensembl chr 4:167,004,245...167,005,183

G

taste receptor, type 2, member 137

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R3 mRNA

NCBI chr 4:70,242,964...70,256,215
Ensembl chr 4:70,251,091...70,252,041

G

taste receptor, type 2, member 138

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R38 mRNA

NCBI chr 4:70,395,042...70,396,037

G

taste receptor, type 2, member 139

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R39 mRNA

NCBI chr 4:71,951,912...71,952,871
Ensembl chr 4:71,951,912...71,952,871

G

taste receptor, type 2, member 144

affects expression

ISO

Asbestos, Crocidolite affects the expression of TAS2R40 mRNA

NCBI chr 4:72,052,815...72,053,774
Ensembl chr 4:72,052,815...72,053,774

G

transcription activation suppressor family member 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TASOR2 mRNA

NCBI chr17:71,504,656...71,559,878
Ensembl chr17:71,504,822...71,559,035

G

taspase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TASP1 mRNA

NCBI chr 3:147,630,092...147,861,710
Ensembl chr 3:147,630,092...147,861,654

G

TBC1 domain family, member 15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBC1D15 mRNA

NCBI chr 7:52,690,770...52,746,309
Ensembl chr 7:52,690,770...52,746,303

G

TBC1 domain family, member 22a

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBC1D22A mRNA

NCBI chr 7:119,172,284...119,457,271
Ensembl chr 7:119,172,333...119,457,271

G

TBC1 domain family, member 31

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBC1D31 mRNA

NCBI chr 7:91,316,905...91,396,434
Ensembl chr 7:91,316,921...91,396,434

G

TBC1 domain family member 9B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBC1D9B mRNA

NCBI chr10:34,961,012...34,998,227
Ensembl chr10:34,960,996...34,998,213

G

tubulin folding cofactor A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBCA mRNA

NCBI chr 2:27,745,985...27,800,624
Ensembl chr 2:27,746,268...27,800,641

G

tubulin folding cofactor E

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TBCE mRNA

NCBI chr17:55,983,627...56,031,578
Ensembl chr17:55,985,707...56,032,302

G

T-box brain transcription factor 1

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TBR1 promoter

NCBI chr 3:66,758,805...66,769,626
Ensembl chr 3:66,759,803...66,769,626

G

T-box transcription factor 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TBX4 gene; Asbestos, Crocidolite results in decreased methylation of TBX4 promoter

PMID:29523930 PMID:29626692

NCBI chr10:71,228,145...71,258,222
Ensembl chr10:71,197,727...71,258,218

G

T-box transcription factor 5

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of TBX5 mRNA
Asbestos, Crocidolite affects the expression of TBX5 mRNA

PMID:17331233 PMID:29279043

NCBI chr12:42,342,926...42,399,723
Ensembl chr12:42,348,485...42,395,359

G

TRPM8 channel-associated factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCAF2 mRNA

G

transcription elongation factor A like 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCEAL3 mRNA

NCBI chr X:104,802,966...104,804,926
Ensembl chr X:104,802,806...104,805,331

G

transcription elongation factor A like 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCEAL8 mRNA

NCBI chr X:103,962,930...103,965,000
Ensembl chr X:103,961,187...103,965,394

G

transcription elongation factor A N-terminal and central domain containing 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCEANC2 mRNA

NCBI chr 5:127,152,776...127,197,405
Ensembl chr 5:127,152,778...127,190,985

G

transcription elongation regulator 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCERG1 mRNA

NCBI chr18:34,756,558...34,817,441
Ensembl chr18:34,756,725...34,817,441

G

transcription factor 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCF12 mRNA

NCBI chr 8:81,371,201...81,682,337
Ensembl chr 8:81,373,321...81,679,922

G

transcription factor 4

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of TCF4 5' UTR; Asbestos, Crocidolite affects the methylation of TCF4 exon

NCBI chr18:65,216,840...65,563,186
Ensembl chr18:65,216,849...65,558,401

G

transcription factor 7 like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCF7L2 mRNA

NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:264,791,335...264,984,225

G

transcobalamin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TCN2 mRNA

NCBI chr14:83,036,935...83,052,187
Ensembl chr14:83,036,935...83,051,552

G

t-complex 11 like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TCP11L1 mRNA

NCBI chr 3:111,478,787...111,547,553
Ensembl chr 3:111,453,221...111,546,454

G

tyrosyl-DNA phosphodiesterase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TDP2 mRNA

NCBI chr17:40,656,969...40,668,362
Ensembl chr17:40,656,971...40,668,288

G

tectonin beta-propeller repeat containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TECPR1 mRNA

NCBI chr12:15,504,456...15,534,541
Ensembl chr12:15,505,343...15,534,116

G

TEF transcription factor, PAR bZIP family member

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TEF mRNA

NCBI chr 7:115,197,180...115,221,930
Ensembl chr 7:115,193,282...115,221,928

G

teneurin transmembrane protein 4

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TENM4 5' UTR

NCBI chr 1:157,699,611...160,674,549
Ensembl chr 1:159,974,017...160,674,549

G

terminal nucleotidyltransferase 5B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TENT5B mRNA

NCBI chr 5:150,979,238...150,986,548
Ensembl chr11:27,212,316...27,214,238
Ensembl chr 5:27,212,316...27,214,238

G

testin LIM domain protein

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TES mRNA

NCBI chr 4:46,331,257...46,369,782
Ensembl chr 4:46,331,257...46,369,780

G

testis expressed 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TEX11 mRNA

NCBI chr X:69,973,012...70,236,544
Ensembl chr X:69,972,723...70,236,011

G

transcription factor AP-2 gamma

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of TFAP2C mRNA
Asbestos, Crocidolite results in decreased expression of TFAP2C mRNA

PMID:18687144 PMID:19446018 PMID:29523930

NCBI chr 3:181,733,524...181,742,412
Ensembl chr 3:181,733,419...181,741,404

G

transcription factor Dp-1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TFDP1 mRNA

NCBI chr16:82,864,220...82,903,166
Ensembl chr16:82,864,226...82,902,996

G

transcription factor Dp-2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TFDP2 mRNA

NCBI chr 8:105,640,018...105,781,026
Ensembl chr 8:105,640,033...105,781,001

G

transcription factor EC

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TFEC mRNA

NCBI chr 4:46,072,093...46,146,200
Ensembl chr 4:46,073,605...46,146,200

G

tissue factor pathway inhibitor

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of TFPI mRNA
Asbestos, Crocidolite results in decreased expression of TFPI mRNA

PMID:18687144 PMID:29279043

NCBI chr 3:89,939,862...89,989,253
Ensembl chr 3:89,939,868...89,980,742

G

tissue factor pathway inhibitor 2

affects expression
multiple interactions
increases secretion
increases expression

ISO

Asbestos, Crocidolite affects the expression of TFPI2 mRNA
IL1RN protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein]; NLRP3 protein affects the reaction [Asbestos, Crocidolite results in increased secretion of TFPI2 protein]
[CASP1 protein affects the susceptibility to Asbestos, Crocidolite] which affects the expression of TFPI2 protein
Asbestos, Crocidolite results in increased expression of TFPI2 mRNA

PMID:18687144 PMID:20831825 PMID:24160326 PMID:25757056 PMID:28056339

NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426

G

transferrin receptor

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TFRC mRNA; Asbestos, Crocidolite results in decreased expression of TFRC protein

NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318

G

transforming growth factor, beta 1

increases activity
multiple interactions
increases expression

ISO

Asbestos, Crocidolite results in increased activity of TGFB1 protein
Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of TGFB1 protein]
Asbestos, Crocidolite results in increased expression of TGFB1 mRNA; Asbestos, Crocidolite results in increased expression of TGFB1 protein

PMID:11250057 PMID:17975199 PMID:26678224 PMID:29553831

NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899

G

transforming growth factor beta 1 induced transcript 1

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of TGFB1I1 mRNA
Asbestos, Crocidolite results in decreased expression of TGFB1I1 mRNA

PMID:17331233 PMID:29279043

NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903

G

transforming growth factor, beta 2

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of TGFB2 mRNA
Asbestos, Crocidolite affects the expression of TGFB2 mRNA

PMID:28056339 PMID:29279043

NCBI chr13:100,691,540...100,793,227
Ensembl chr13:100,692,953...100,792,856

G

TGFB-induced factor homeobox 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TGIF1 mRNA

NCBI chr 9:118,194,735...118,204,354
Ensembl chr 9:118,194,444...118,204,442

G

transglutaminase 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TGM2 mRNA

NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240

G

transglutaminase 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TGM3 mRNA

NCBI chr 3:137,681,809...137,717,219
Ensembl chr 3:137,681,809...137,717,219

G

transglutaminase 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TGM5 mRNA

NCBI chr 3:128,461,836...128,497,761
Ensembl chr 3:128,461,836...128,497,761

G

THAP domain containing 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of THAP12 mRNA

NCBI chr 1:162,414,781...162,430,560
Ensembl chr 1:162,414,723...162,430,551

G

thrombospondin 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of THBS1 protein

NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402

G

thrombospondin 2

multiple interactions
decreases expression

ISO

SETD2 protein affects the reaction [Asbestos, Crocidolite results in decreased expression of THBS2 mRNA]

NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918

G

thymocyte selection associated family member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of THEMIS2 mRNA

NCBI chr 5:150,275,094...150,290,343
Ensembl chr 5:150,275,094...150,290,343

G

THO complex subunit 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of THOC1 mRNA

NCBI chr18:1,253,041...1,291,956
Ensembl chr18:1,256,637...1,292,630

G

THO complex subunit 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of THOC2 mRNA

NCBI chr X:125,500,549...125,615,139
Ensembl chr X:125,500,549...125,615,087

G

THO complex subunit 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of THOC3 mRNA

NCBI chr17:10,148,281...10,157,472
Ensembl chr17:10,147,981...10,158,275

G

thyroid hormone receptor alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of THRA mRNA

NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657

G

thyroid hormone receptor associated protein 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of THRAP3 mRNA

NCBI chr 5:143,729,821...143,772,105
Ensembl chr 5:143,730,596...143,771,983

G

thrombospondin type 1 domain containing 7B

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of THSD7B 5' UTR

NCBI chr13:43,320,895...44,219,546
Ensembl chr13:43,320,891...44,218,785

G

THUMP domain containing 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of THUMPD3 mRNA

NCBI chr 4:147,741,288...147,764,254
Ensembl chr 4:147,741,309...147,765,579

G

Thy-1 cell surface antigen

increases expression

ISO

Asbestos, Crocidolite results in increased expression of THY1 mRNA

NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540

G

Tia1 cytotoxic granule-associated RNA binding protein-like 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TIAL1 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:192,438,794...192,475,520
Ensembl chr 1:192,441,247...192,475,674

G

TIAM Rac1 associated GEF 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TIAM2 promoter

NCBI chr 1:46,323,450...46,524,769
Ensembl chr 1:46,323,456...46,524,769

G

TIR domain containing adaptor molecule 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TICAM1 mRNA

NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892

G

timeless circadian regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TIMELESS mRNA

NCBI chr 7:1,239,388...1,263,344
Ensembl chr 7:1,239,450...1,263,337

G

translocase of inner mitochondrial membrane 21

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TIMM21 mRNA

NCBI chr18:80,589,775...80,594,237
Ensembl chr18:80,589,783...80,594,237

G

TIMP metallopeptidase inhibitor 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TIMP1
Asbestos, Crocidolite results in increased expression of TIMP1 mRNA

PMID:16574944 PMID:28056339

NCBI chr X:3,766,509...3,772,578
Ensembl chr X:3,766,510...3,771,135

G

TIMP metallopeptidase inhibitor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TIMP2

NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214

G

TCDD-inducible poly(ADP-ribose) polymerase

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TIPARP mRNA

NCBI chr 2:152,063,769...152,090,414
Ensembl chr 2:152,063,751...152,090,406

G

TOR signaling pathway regulator

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TIPRL mRNA

NCBI chr13:80,060,193...80,085,040
Ensembl chr13:80,039,673...80,085,040

G

tight junction protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TJP1 protein
Asbestos, Crocidolite results in decreased expression of TJP1 mRNA

PMID:22573546 PMID:29279043

NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158

G

transketolase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TKT mRNA

NCBI chr16:5,729,381...5,755,170
Ensembl chr16:5,729,991...5,756,431

G

TLC domain containing 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TLCD1 mRNA

NCBI chr10:63,572,541...63,574,574
Ensembl chr10:63,572,518...63,574,567

G

TLE family member 4, transcriptional corepressor

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TLE4 mRNA

NCBI chr 1:221,086,250...221,222,826
Ensembl chr 1:221,086,253...221,222,826

G

toll-like receptor 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TLR2 mRNA

PMID:23634900 PMID:25351596

NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194

G

toll-like receptor 8

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TLR8 mRNA

NCBI chr X:30,708,714...30,733,104
Ensembl chr X:30,708,033...30,737,079

G

T-cell leukemia homeobox 2

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TLX2 promoter

NCBI chr 4:117,131,516...117,133,359
Ensembl chr 4:117,131,516...117,133,359

G

transmembrane 4 L six family member 1

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of TM4SF1 mRNA
Asbestos, Crocidolite results in decreased expression of TM4SF1 mRNA

PMID:25351596 PMID:29523930

NCBI chr 2:143,606,980...143,616,176
Ensembl chr 2:143,603,271...143,616,176

G

transmembrane 4 L six family member 20

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TM4SF20 mRNA

NCBI chr 9:91,486,847...91,500,745
Ensembl chr 9:91,486,847...91,500,745

G

transmembrane 7 superfamily member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TM7SF2 mRNA

NCBI chr 1:212,785,217...212,789,572
Ensembl chr 1:212,785,217...212,789,557

G

translation machinery associated 7 homolog

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMA7 mRNA

NCBI chr 8:118,604,680...118,609,368
Ensembl chr 8:118,604,680...118,609,368

G

transmembrane BAX inhibitor motif containing 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMBIM1 mRNA

NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:83,320,979...83,338,657

G

transmembrane and coiled-coil domain family 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMCC3 mRNA

NCBI chr 7:30,781,452...31,058,888
Ensembl chr 7:30,897,991...31,058,889

G

transmembrane p24 trafficking protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMED1 mRNA

NCBI chr 8:28,336,072...28,342,853
Ensembl chr 8:28,336,074...28,338,841

G

transmembrane protein 101

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM101 mRNA

NCBI chr10:87,605,300...87,609,053
Ensembl chr10:87,605,300...87,608,999

G

transmembrane protein 106B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM106B mRNA

NCBI chr 4:42,294,074...42,313,426
Ensembl chr 4:42,294,101...42,313,407

G

transmembrane protein 106C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM106C mRNA

NCBI chr 7:130,967,526...130,973,205
Ensembl chr 7:130,967,606...130,973,207

G

transmembrane protein 134

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM134 mRNA

NCBI chr 1:210,848,761...210,857,735
Ensembl chr 1:210,848,578...210,858,861

G

transmembrane protein 140

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM140 mRNA

NCBI chr 4:64,503,621...64,514,620
Ensembl chr 4:64,500,439...64,521,990

G

transmembrane protein 14A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM14A mRNA

NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:31,136,963...31,148,800

G

transmembrane protein 150B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM150B mRNA

NCBI chr 1:78,153,729...78,164,149
Ensembl chr 1:78,153,961...78,169,810

G

transmembrane protein 151A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM151A mRNA

NCBI chr 1:211,816,773...211,821,558
Ensembl chr 1:211,816,773...211,822,317

G

transmembrane protein 156

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM156 mRNA

NCBI chr14:43,568,131...43,606,109
Ensembl chr14:43,577,023...43,606,109

G

transmembrane protein 158

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM158 mRNA

NCBI chr 8:131,791,137...131,792,135
Ensembl chr 8:131,787,277...131,796,882

G

transmembrane protein 17

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM17 mRNA

NCBI chr14:100,684,655...100,725,471
Ensembl chr14:100,685,093...100,725,470

G

transmembrane protein 176A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM176A mRNA

NCBI chr 4:79,101,946...79,109,499
Ensembl chr 4:79,101,857...79,111,175

G

transmembrane protein 182

decreases methylation

ISO

Asbestos, Crocidolite results in decreased methylation of TMEM182 5' UTR

NCBI chr 9:50,555,029...50,606,908
Ensembl chr 9:50,550,462...50,606,907

G

transmembrane protein 183A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM183A mRNA

NCBI chr13:48,355,664...48,372,437
Ensembl chr13:48,355,889...48,372,381

G

transmembrane protein 19

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM19 mRNA

NCBI chr 7:52,844,985...52,871,708
Ensembl chr 7:52,844,985...52,872,012

G

transmembrane protein 191C

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM191C mRNA

NCBI chr11:97,230,390...97,232,481
Ensembl chr11:97,229,419...97,237,082

G

transmembrane protein 204

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM204 mRNA

NCBI chr10:14,581,025...14,608,878
Ensembl chr10:14,581,026...14,606,427

G

transmembrane protein 219

increases expression
decreases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM219 mRNA
Asbestos, Crocidolite results in decreased expression of TMEM219 mRNA

PMID:29279043 PMID:29523930

NCBI chr 1:190,926,722...190,965,044
Ensembl chr 1:190,926,722...190,958,912

G

transmembrane protein 231

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM231 mRNA

NCBI chr19:56,792,329...56,813,515
Ensembl chr19:56,792,329...56,820,094

G

transmembrane protein 248

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM248 mRNA

NCBI chr12:32,069,113...32,093,380
Ensembl chr12:32,069,120...32,090,634

G

transmembrane protein 259

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM259 mRNA

NCBI chr 7:10,374,804...10,381,566
Ensembl chr 7:10,373,119...10,381,566

G

transmembrane protein 266

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM266 mRNA

NCBI chr 8:64,603,199...64,716,770
Ensembl chr 8:64,603,186...64,716,769

G

transmembrane protein 267

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM267 mRNA

NCBI chr 2:53,309,857...53,321,466
Ensembl chr 2:53,313,021...53,320,835

G

transmembrane protein 39b

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of TMEM39B gene

NCBI chr 5:147,308,616...147,330,895
Ensembl chr 5:147,308,621...147,336,496

G

transmembrane protein 40

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM40 mRNA

NCBI chr 4:150,464,123...150,491,895
Ensembl chr 4:150,464,128...150,492,183

G

transmembrane protein 47

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM47 mRNA

NCBI chr X:49,338,532...49,365,026
Ensembl chr X:49,338,326...49,521,541

G

transmembrane protein 51

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMEM51 mRNA

NCBI chr 5:159,608,865...159,658,918
Ensembl chr 5:159,608,866...159,658,891

G

transmembrane protein 62

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM62 mRNA

NCBI chr 3:128,380,366...128,415,583
Ensembl chr 3:128,375,500...128,415,583

G

transmembrane protein 64

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM64 mRNA

NCBI chr 5:33,495,992...33,542,390
Ensembl chr 5:33,496,032...33,542,389

G

transmembrane protein 69

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM69 mRNA

NCBI chr 5:135,241,557...135,247,323
Ensembl chr 5:135,241,560...135,247,215

G

transmembrane protein 71

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM71 mRNA

NCBI chr 7:100,166,038...100,212,234
Ensembl chr 7:100,166,516...100,204,969

G

TMEM9 domain family, member B

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMEM9B mRNA

NCBI chr 1:173,199,225...173,218,674
Ensembl chr 1:173,200,869...173,218,053

G

TATA element modulatory factor 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMF1 mRNA

NCBI chr 4:131,316,630...131,345,666
Ensembl chr 4:131,311,801...131,342,436

G

trimethyllysine hydroxylase, epsilon

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMLHE mRNA

NCBI chr20:96,561...144,414
Ensembl chr20:107,516...144,543

G

thymopoietin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMPO mRNA

NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937

G

transmembrane serine protease 11D

increases expression
decreases methylation

ISO

Asbestos, Crocidolite results in increased expression of TMPRSS11D mRNA
Asbestos, Crocidolite results in decreased methylation of TMPRSS11D gene

PMID:25351596 PMID:29523930

NCBI chr14:22,062,129...22,124,189
Ensembl chr14:22,062,131...22,124,505

G

transmembrane serine protease 11E

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TMPRSS11E mRNA

NCBI chr14:21,638,418...21,683,029
Ensembl chr14:21,638,418...21,683,029

G

transmembrane serine protease 15

affects expression

ISO

Asbestos, Crocidolite affects the expression of TMPRSS15 mRNA

NCBI chr11:31,164,633...31,289,143
Ensembl chr11:31,164,633...31,288,953

G

thiol methyltransferase 1A

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMT1A mRNA

NCBI chr 7:133,330,141...133,377,172
Ensembl chr 7:133,330,447...133,338,959

G

transmembrane O-mannosyltransferase targeting cadherins 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMTC1 mRNA

NCBI chr 4:182,874,350...183,089,408
Ensembl chr 4:182,878,802...183,102,532

G

thioredoxin-related transmembrane protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TMX1 mRNA

NCBI chr 6:94,696,699...94,707,751
Ensembl chr 6:94,696,358...94,708,618

G

thioredoxin-related transmembrane protein 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TMX3 mRNA

NCBI chr18:86,021,137...86,054,025
Ensembl chr18:86,021,084...86,054,198

G

tumor necrosis factor

increases expression
affects expression
increases secretion
multiple interactions

ISO
EXP

Asbestos, Crocidolite results in increased expression of TNF mRNA; Asbestos, Crocidolite results in increased expression of TNF protein
Asbestos, Crocidolite affects the expression of TNF mRNA
Asbestos, Crocidolite results in increased secretion of TNF protein
[Asbestos, Crocidolite results in decreased susceptibility to Asbestos, Crocidolite] which results in decreased expression of TNF protein; [TNF protein co-treated with Asbestos, Crocidolite] results in increased secretion of IL1RN protein; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL1B protein]; Asbestos, Crocidolite promotes the reaction [TNF protein results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of CXCL8 protein]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of HMGB1 protein]; TNF protein inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; TNF protein promotes the reaction [Asbestos, Crocidolite affects the localization of CTNNB1 protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]
[Asbestos, Crocidolite co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Dimethyl Sulfoxide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; SN50 peptide inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Sodium Azide promotes the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF mRNA]; tetramethylthiourea inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Asbestos, Crocidolite results in increased secretion of CCL2 protein]
2-thiomalic acid promotes the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Ditiocarb inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; formic acid inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; Lignans inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF protein]; NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased expression of TNF mRNA]; NOS2 gene mutant form inhibits the reaction [Asbestos, Crocidolite results in increased secretion of TNF protein]; SOD1 protein promotes the reaction [Asbestos, Crocidolite results in increased expression of TNF protein]

PMID:7539275 PMID:7849857 PMID:8473757 PMID:9400719 PMID:10486238 More...

NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303

G

TNF alpha induced protein 2

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of TNFAIP2 mRNA
Asbestos, Crocidolite affects the expression of TNFAIP2 mRNA

PMID:24160326 PMID:25351596 PMID:25757056

NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:136,298,082...136,311,106

G

TNF alpha induced protein 3

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of TNFAIP3 mRNA
Asbestos, Crocidolite affects the expression of TNFAIP3 mRNA

PMID:18687144 PMID:24160326 PMID:25351596 PMID:25757056

NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979

G

TNF alpha induced protein 6

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNFAIP6 mRNA

PMID:24160326 PMID:25351596 PMID:25757056

NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796

G

TNF alpha induced protein 8

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of TNFAIP8 mRNA
Asbestos, Crocidolite results in increased expression of TNFAIP8 mRNA

PMID:24160326 PMID:25757056

NCBI chr18:45,370,334...45,486,036
Ensembl chr18:45,370,406...45,486,036

G

TNF alpha induced protein 8 like 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNFAIP8L1 mRNA

NCBI chr 9:1,075,724...1,088,256
Ensembl chr 9:1,055,801...1,092,803

G

TNF receptor superfamily member 11B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNFRSF11B mRNA

NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075

G

TNF receptor superfamily member 12A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNFRSF12A mRNA

NCBI chr10:13,211,670...13,213,666
Ensembl chr10:13,211,673...13,213,704

G

TNF receptor superfamily member 13C

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TNFRSF13C mRNA

NCBI chr 7:115,616,139...115,618,647
Ensembl chr 7:115,616,303...115,618,620

G

TNF receptor superfamily member 1A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNFRSF1A mRNA; Asbestos, Crocidolite results in increased expression of TNFRSF1A protein

NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:159,837,032...159,849,816

G

TNF receptor superfamily member 21

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of TNFRSF21 promoter

NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323

G

TNF superfamily member 10

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TNFSF10 mRNA

NCBI chr 2:112,136,550...112,155,903

G

TNFAIP3 interacting protein 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TNIP1 mRNA

NCBI chr10:39,537,759...39,585,038
Ensembl chr10:39,537,437...39,585,158

G

tyrosine kinase, non-receptor, 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TNK1 mRNA

NCBI chr10:55,070,362...55,084,383
Ensembl chr10:55,069,837...55,078,710

G

tankyrase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TNKS mRNA

NCBI chr16:63,922,969...64,073,972
Ensembl chr16:63,928,281...64,079,282

G

trinucleotide repeat containing 18

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TNRC18 mRNA

NCBI chr12:16,868,930...16,965,224
Ensembl chr12:16,868,978...16,965,217

G

tensin 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TNS2 mRNA

NCBI chr 7:135,108,401...135,126,505
Ensembl chr 7:135,108,202...135,126,504

G

tenascin XA, pseudogene 1

affects methylation

ISO

Asbestos, Crocidolite affects the methylation of TNXA 5' UTR

NCBI chr20:4,031,091...4,032,446

G

tenascin XB

affects methylation
decreases methylation

ISO

Asbestos, Crocidolite affects the methylation of TNXB 5' UTR; Asbestos, Crocidolite affects the methylation of TNXB exon
Asbestos, Crocidolite results in decreased methylation of TNXB 5' UTR

Ensembl chr20:4,031,082...4,090,128

G

TOG array regulator of axonemal microtubules 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TOGARAM1 mRNA

NCBI chr 6:88,755,264...88,819,599
Ensembl chr 6:88,755,264...88,819,598

G

translocase of outer mitochondrial membrane 5

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TOMM5 mRNA

NCBI chr 5:64,158,026...64,160,857

G

DNA topoisomerase I mitochondrial

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TOP1MT mRNA

NCBI chr 7:109,223,269...109,248,855
Ensembl chr 7:109,139,527...109,246,799

G

DNA topoisomerase II beta

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TOP2B mRNA

NCBI chr15:11,482,089...11,542,464
Ensembl chr15:11,482,089...11,542,464

G

TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TOPORS mRNA

NCBI chr 5:60,184,076...60,195,979
Ensembl chr 5:60,182,035...60,194,706

G

TOX high mobility group box family member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TOX2 mRNA

NCBI chr 3:172,272,718...172,400,235
Ensembl chr 3:172,272,736...172,400,233

G

tumor protein p53

increases expression
affects response to substance
multiple interactions
decreases expression
affects expression
increases response to substance
increases mutagenesis
increases phosphorylation

ISO

Asbestos, Crocidolite results in increased expression of TP53 protein
TRP53 protein affects the susceptibility to Asbestos, Crocidolite
Asbestos, Crocidolite results in decreased expression of and results in increased phosphorylation of TP53 protein; Asbestos, Crocidolite results in increased phosphorylation of and results in increased stability of TP53 protein
Asbestos, Crocidolite results in decreased expression of TP53 protein; Asbestos, Crocidolite results in decreased expression of TP53 protein modified form
Asbestos, Crocidolite affects the expression of TP53 mRNA; Asbestos, Crocidolite affects the expression of TP53 protein
OGG1 protein mutant form promotes the reaction [Asbestos, Crocidolite results in increased expression of TRP53 protein]
TRP53 gene mutant form results in increased susceptibility to Asbestos, Crocidolite
Asbestos, Crocidolite results in increased mutagenesis of TRP53 exon
Asbestos, Crocidolite results in increased phosphorylation of TP53 protein

PMID:9400702 PMID:10992274 PMID:12151629 PMID:12676607 PMID:17331233 More...

NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299

G

tumor protein p53 binding protein 1

decreases expression
affects expression

ISO

Asbestos, Crocidolite results in decreased expression of TRP53BP1 mRNA
Asbestos, Crocidolite affects the expression of TP53BP1 mRNA

PMID:17331233 PMID:29279043

NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747

G

tumor protein p53 inducible nuclear protein 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRP53INP1 mRNA

NCBI chr 5:29,051,267...29,069,486
Ensembl chr 5:29,051,264...29,069,484

G

tumor protein p53 inducible nuclear protein 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRP53INP2 mRNA

NCBI chr 3:164,341,618...164,350,270
Ensembl chr 3:164,343,205...164,350,225

G

Tp53 tumor protein p53 regulating kinase A

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TP53RK mRNA

NCBI chr 3:174,638,962...174,645,198
Ensembl chr 3:174,638,962...174,643,347

G

tumor protein p63

affects expression

ISO

Asbestos, Crocidolite affects the expression of TP63 mRNA

NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177

G

tumor protein D52

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TPD52 mRNA

NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:94,642,585...94,724,241

G

tropomyosin 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TPM1 mRNA

NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:76,511,871...76,543,468

G

tripeptidyl peptidase 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TPP2 mRNA

NCBI chr 9:53,538,788...53,620,253
Ensembl chr 9:53,538,313...53,620,251

G

tubulin polymerization-promoting protein family member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TPPP2 mRNA

NCBI chr15:27,087,457...27,090,869

G

Tp53rk binding protein

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TPRKB mRNA

NCBI chr 4:119,900,374...119,915,374
Ensembl chr 4:119,900,484...119,915,382

G

transformer 2 alpha

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRA2A mRNA

NCBI chr 4:79,551,699...79,570,621
Ensembl chr 4:79,551,542...79,570,619

G

TNF receptor-associated factor 1

increases expression
affects expression

ISO

Asbestos, Crocidolite results in increased expression of TRAF1 mRNA
Asbestos, Crocidolite affects the expression of TRAF1 mRNA

PMID:24160326 PMID:25757056

NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:38,619,506...38,636,264

G

TRAF3 interacting protein 3

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRAF3IP3 mRNA

NCBI chr13:107,223,499...107,248,358
Ensembl chr13:107,223,502...107,248,155

G

TNF receptor-associated protein 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRAP1 mRNA

NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,970,995...12,005,355

G

trafficking protein particle complex subunit 6B

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRAPPC6B mRNA

NCBI chr 6:82,475,794...82,486,928
Ensembl chr 6:82,475,320...82,493,447

G

triggering receptor expressed on myeloid cells 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TREM1 mRNA

NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:20,261,408...20,276,892

G

triggering receptor expressed on myeloid cells 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TREM2 mRNA

NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779

G

transcriptional regulating factor 1

affects expression

ISO

Asbestos, Crocidolite affects the expression of TRERF1 mRNA

NCBI chr 9:21,131,772...21,355,830
Ensembl chr 9:21,131,777...21,176,016

G

tribbles pseudokinase 1

affects expression
increases expression

ISO

Asbestos, Crocidolite affects the expression of TRIB1 mRNA
Asbestos, Crocidolite results in increased expression of TRIB1 mRNA

PMID:17331233 PMID:18687144

NCBI chr 7:93,096,001...93,102,547
Ensembl chr 7:93,095,973...93,117,480

G

tribbles pseudokinase 2

affects expression
decreases expression

ISO

Asbestos, Crocidolite affects the expression of TRIB2 mRNA
Asbestos, Crocidolite results in decreased expression of TRIB2 mRNA

PMID:17331233 PMID:29279043

NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:44,274,762...44,299,094

G

tribbles pseudokinase 3

affects expression

ISO

Asbestos, Crocidolite affects the expression of TRIB3 mRNA

PMID:17331233 PMID:25757056

NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802

G

tripartite motif-containing 21

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRIM21 mRNA

NCBI chr 1:166,376,829...166,399,441
Ensembl chr 1:166,376,829...166,399,449

G

tripartite motif-containing 31

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of TRIM31 gene

NCBI chr20:1,658,386...1,671,711
Ensembl chr20:1,658,386...1,671,711

G

tripartite motif-containing 35

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRIM35 mRNA

NCBI chr15:44,669,222...44,685,766
Ensembl chr15:44,656,322...44,685,765

G

tripartite motif-containing 45

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRIM45 mRNA

NCBI chr 2:191,038,355...191,047,826
Ensembl chr 2:191,038,356...191,047,825

G

tripartite motif-containing 47

affects expression

ISO

Asbestos, Crocidolite affects the expression of TRIM47 mRNA

NCBI chr10:101,836,465...101,840,936
Ensembl chr10:101,836,465...101,840,936

G

tripartite motif-containing 54

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRIM54 mRNA

NCBI chr 6:30,959,306...30,978,475
Ensembl chr 6:30,959,306...30,978,475

G

tripartite motif-containing 59

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRIM59 mRNA

NCBI chr 2:155,579,183...155,593,450
Ensembl chr 2:155,567,115...155,598,645

G

tripartite motif family-like 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRIML2 mRNA

NCBI chr16:55,677,142...55,693,379
Ensembl chr16:55,677,142...55,693,379

G

thyroid hormone receptor interactor 11

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRIP11 mRNA

NCBI chr 6:126,760,263...126,832,619
Ensembl chr 6:126,760,265...126,832,570

G

tRNA isopentenyltransferase 1

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRIT1 mRNA

NCBI chr 5:140,578,459...140,623,881
Ensembl chr 5:140,580,453...140,623,881

G

tRNA methyltransferase 1-like

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TRMT1L mRNA

NCBI chr13:66,060,186...66,093,247
Ensembl chr13:66,060,162...66,093,643

G

transient receptor potential cation channel, subfamily M, member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TRPM1 mRNA

NCBI chr 1:127,130,686...127,247,219
Ensembl chr 1:127,130,686...127,247,391

G

TSC22 domain family, member 1

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSC22D1 mRNA

PMID:18687144 PMID:25757056

NCBI chr15:58,159,612...58,260,244
Ensembl chr15:58,159,952...58,183,322

G

TSC22 domain family, member 2

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSC22D2 mRNA

NCBI chr 2:144,796,760...144,847,930
Ensembl chr 2:144,796,841...144,843,559

G

TSC22 domain family, member 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSC22D3 mRNA

NCBI chr X:109,006,410...109,066,389
Ensembl chr X:109,006,420...109,015,519

G

tRNA splicing endonuclease subunit 15

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSEN15 mRNA

NCBI chr13:67,040,134...67,055,509
Ensembl chr13:67,040,134...67,055,509

G

tRNA splicing endonuclease subunit 34

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSEN34 mRNA

NCBI chr 1:74,432,687...74,440,553
Ensembl chr 1:74,432,685...74,440,832

G

Ts translation elongation factor, mitochondrial

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSFM mRNA

NCBI chr 7:64,714,330...64,750,106
Ensembl chr 7:64,714,036...64,750,171

G

thymic stromal lymphopoietin

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSLP mRNA

NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,720,257...24,728,420

G

translin

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSN mRNA

NCBI chr13:31,917,133...31,930,069
Ensembl chr13:31,919,231...31,930,417

G

translin-associated factor X

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSNAX mRNA

NCBI chr19:69,873,210...69,887,244
Ensembl chr19:69,872,987...69,887,224

G

tetraspanin 18

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TSPAN18 mRNA

NCBI chr 3:99,615,465...99,755,270
Ensembl chr 3:99,615,466...99,755,270

G

tetraspanin 3

decreases methylation
decreases expression

ISO

Asbestos, Crocidolite results in decreased methylation of TSPAN3 gene
Asbestos, Crocidolite results in decreased expression of TSPAN3 mRNA

PMID:29279043 PMID:29523930

NCBI chr 8:65,442,100...65,465,961
Ensembl chr 8:65,442,101...65,465,844

G

tetraspanin 31

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSPAN31 mRNA

NCBI chr 7:64,774,881...64,783,534
Ensembl chr 7:64,774,910...64,777,726

G

tetraspanin 6

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSPAN6 mRNA

NCBI chr X:101,385,686...101,395,371
Ensembl chr X:101,385,694...101,392,627

G

TSPY-like 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSPYL2 mRNA

NCBI chr X:24,918,851...24,924,462
Ensembl chr X:24,918,851...24,924,462

G

thiosulfate sulfurtransferase like domain containing 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TSTD3 mRNA

NCBI chr 5:40,091,438...40,101,509
Ensembl chr 5:40,065,807...40,100,878

G

tau tubulin kinase 1

increases methylation

ISO

Asbestos, Crocidolite results in increased methylation of TTBK1 5' UTR

NCBI chr 9:21,990,973...22,035,961
Ensembl chr 9:21,990,973...22,035,961

G

tetratricopeptide repeat domain 12

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TTC12 mRNA

NCBI chr 8:58,696,381...58,743,857
Ensembl chr 8:58,696,385...58,742,717

G

tetratricopeptide repeat domain 13

increases expression

ISO

Asbestos, Crocidolite results in increased expression of TTC13 mRNA

NCBI chr19:69,534,989...69,589,590
Ensembl chr19:69,534,989...69,589,563

G

tetratricopeptide repeat domain 3

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TTC3 mRNA

NCBI chr11:47,158,766...47,258,612
Ensembl chr11:47,158,792...47,258,418

G

tetratricopeptide repeat domain 33

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TTC33 mRNA

NCBI chr 2:56,007,377...56,054,312
Ensembl chr 2:56,007,316...56,054,326

G

transcription termination factor 2

decreases expression

ISO

Asbestos, Crocidolite results in decreased expression of TTF2 mRNA

NCBI chr 2:191,054,942...191,086,331
Ensembl chr 2:191,054,966...191,086,386

G

tubulin tyrosine ligase like 7

decreases expression

ISO