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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:vorinostat
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Accession:CHEBI:45716 term browser browse the term
Definition:A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Synonyms:exact_synonym: N-hydroxy-N'-phenyloctanediamide
 related_synonym: Formula=C14H20N2O3;   InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18);   InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N;   SAHA;   SHH;   SMILES=ONC(=O)CCCCCCC(=O)Nc1ccccc1;   Suberanilohydroxamic acid;   Zolinza;   octanedioic acid hydroxyamide phenylamide;   suberoylanilide hydroxamic acid;   vorinostatum
 xref: CAS:149647-78-9;   DrugBank:DB02546;   Drug_Central:4124;   HMDB:HMDB0015568;   KEGG:D06320;   LINCS:LSM-3828
 xref_mesh: MESH:C111237
 xref: PDBeChem:SHH;   PMID:21657958;   PMID:22887890;   PMID:23320102;   PMID:23348693;   PMID:23708756;   PMID:23758082;   PMID:23820962;   PMID:23864881;   Patent:CN102641261;   Patent:KR20110045493;   Patent:NZ592686;   Patent:US2011039937;   Patent:WO2008106524;   Reaxys:7213017;   Wikipedia:Vorinostat


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      CHEBI ontology 26835
        role 26662
          biological role 26641
            biochemical role 25894
              apoptosis inducer 15068
                vorinostat 2765
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      CHEBI ontology 26835
        subatomic particle 26811
          composite particle 26811
            hadron 26811
              baryon 26811
                nucleon 26811
                  atomic nucleus 26811
                    atom 26811
                      main group element atom 26561
                        p-block element atom 26561
                          carbon group element atom 26043
                            carbon atom 26006
                              organic molecular entity 26006
                                heteroorganic entity 25388
                                  organochalcogen compound 24998
                                    organooxygen compound 24630
                                      carbon oxoacid 22992
                                        carboxylic acid 22979
                                          carboacyl group 20183
                                            univalent carboacyl group 20183
                                              carbamoyl group 19705
                                                carboxamide 19705
                                                  dicarboxylic acid amide 3337
                                                    dicarboxylic acid diamide 2860
                                                      vorinostat 2765
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