|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity |
ISO |
Ethylmaleimide results in decreased activity of ABCB1 protein |
CTD |
PMID:2900677 |
|
NCBI chr 4:26,312,403...26,488,456
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects activity multiple interactions |
ISO |
Ethylmaleimide affects the activity of ABCC1 protein Ethylmaleimide inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein] |
CTD |
PMID:9096673 PMID:9334814 PMID:16101123 |
|
NCBI chr10:1,022,041...1,162,431
|
|
G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
decreases activity |
EXP |
Ethylmaleimide results in decreased activity of ACSL4 protein |
CTD |
PMID:11319222 |
|
NCBI chr X:110,739,633...110,803,416
|
|
G |
Alb |
albumin |
decreases transport |
EXP |
Ethylmaleimide results in decreased transport of ALB protein |
CTD |
PMID:15897811 |
|
NCBI chr14:17,891,564...17,907,043
|
|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [APEX1 protein inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]] |
CTD |
PMID:23370007 |
|
NCBI chr15:24,144,595...24,146,785
|
|
G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions increases glutathionylation |
ISO |
Dithiothreitol inhibits the reaction [Ethylmaleimide results in increased glutathionylation of ATP7A protein] |
CTD |
PMID:20566629 |
|
NCBI chr X:75,159,635...75,267,094
|
|
G |
Atp8b1 |
ATPase phospholipid transporting 8B1 |
multiple interactions |
EXP |
Ethylmaleimide inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] |
CTD |
PMID:11584374 |
|
NCBI chr18:60,286,605...60,427,862
|
|
G |
Cbr2 |
carbonyl reductase 2 |
increases acylation |
ISO |
Ethylmaleimide results in increased acylation of CBR2 protein |
CTD |
PMID:18597497 |
|
NCBI chr10:106,008,535...106,012,838
|
|
G |
Cftr |
CF transmembrane conductance regulator |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein] |
CTD |
PMID:15657297 |
|
NCBI chr 4:47,422,084...47,694,646
|
|
G |
Chat |
choline O-acetyltransferase |
decreases activity |
ISO |
Ethylmaleimide results in decreased activity of CHAT protein |
CTD |
PMID:3437937 |
|
NCBI chr16:7,657,362...7,717,093
|
|
G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] |
CTD |
PMID:10820281 |
|
NCBI chr 1:252,908,748...252,944,273
|
|
G |
Dusp23 |
dual specificity phosphatase 23 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [DUSP23 protein results in decreased phosphorylation of nitrophenylphosphate] |
CTD |
PMID:15147733 |
|
NCBI chr13:85,097,899...85,100,054
|
|
G |
F3 |
coagulation factor III, tissue factor |
increases expression |
ISO |
Ethylmaleimide results in increased expression of F3 protein |
CTD |
PMID:25569083 |
|
NCBI chr 2:212,511,675...212,523,375
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
decreases activity |
ISO |
Ethylmaleimide results in decreased activity of GAD1 protein |
CTD |
PMID:15836621 |
|
NCBI chr 3:75,777,260...75,818,099
|
|
G |
Gad2 |
glutamate decarboxylase 2 |
decreases activity |
ISO |
Ethylmaleimide results in decreased activity of GAD2 protein |
CTD |
PMID:15836621 |
|
NCBI chr17:89,671,718...89,734,246
|
|
G |
Hoxb13 |
homeo box B13 |
increases response to substance |
ISO |
HOXB13 protein results in increased susceptibility to Ethylmaleimide |
CTD |
PMID:24213000 |
|
NCBI chr10:81,160,498...81,162,777
|
|
G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions |
ISO |
Ethylmaleimide promotes the reaction [Thiram results in decreased activity of HSD11B2 protein] |
CTD |
PMID:22796344 |
|
NCBI chr19:50,307,569...50,312,812
|
|
G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein] |
CTD |
PMID:7476933 |
|
NCBI chr 3:136,979,804...136,990,236
|
|
G |
Ltbr |
lymphotoxin beta receptor |
multiple interactions |
ISO |
Ethylmaleimide promotes the reaction [OSM protein binds to LTBR protein] |
CTD |
PMID:37193757 |
|
NCBI chr 4:158,108,884...158,115,339
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [APEX1 protein inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]] |
CTD |
PMID:23370007 |
|
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mt3 |
metallothionein 3 |
increases alkylation |
ISO |
Ethylmaleimide results in increased alkylation of MT3 protein |
CTD |
PMID:12383939 |
|
NCBI chr19:10,848,754...10,850,158
|
|
G |
Osm |
oncostatin M |
multiple interactions |
ISO |
Ethylmaleimide promotes the reaction [OSM protein binds to LTBR protein] |
CTD |
PMID:37193757 |
|
NCBI chr14:79,103,638...79,108,500
|
|
G |
Pah |
phenylalanine hydroxylase |
multiple interactions |
ISO |
Ethylmaleimide results in increased activity of [PAH protein binds to PAH protein binds to PAH protein binds to PAH protein] |
CTD |
PMID:19367645 |
|
NCBI chr 7:21,933,179...21,998,134
|
|
G |
Senp1 |
SUMO specific peptidase 1 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP1 protein] |
CTD |
PMID:26060329 |
|
NCBI chr 7:131,042,237...131,105,826
|
|
G |
Senp6 |
SUMO specific peptidase 6 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP6 protein] |
CTD |
PMID:26060329 |
|
NCBI chr 8:80,988,675...81,071,606
|
|
G |
Slc12a5 |
solute carrier family 12 member 5 |
increases activity multiple interactions |
ISO |
Ethylmaleimide results in increased activity of SLC12A5 protein Ethylmaleimide inhibits the reaction [SLC12A5 protein results in increased import of Thallium] |
CTD |
PMID:20086212 |
|
NCBI chr 3:153,696,517...153,735,801
|
|
G |
Slc16a1 |
solute carrier family 16 member 1 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [SLC16A1 protein results in increased uptake of Lactic Acid] |
CTD |
PMID:15804185 |
|
NCBI chr 2:194,805,556...194,832,966
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 protein] |
CTD |
PMID:7476933 |
|
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Sp1 |
Sp1 transcription factor |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [CD 437 results in increased cleavage of SP1 protein] |
CTD |
PMID:9343396 |
|
NCBI chr 7:135,419,864...135,450,513
|
|
G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP1 protein]; Ethylmaleimide inhibits the reaction [SUMO2 protein binds to SENP6 protein] |
CTD |
PMID:26060329 |
|
NCBI chr10:100,771,941...100,784,503
|
|
G |
Tf |
transferrin |
decreases uptake |
ISO |
Ethylmaleimide results in decreased uptake of TF protein |
CTD |
PMID:10865941 |
|
NCBI chr 8:103,789,780...103,816,487
|
|
G |
Th |
tyrosine hydroxylase |
multiple interactions |
EXP |
Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein] |
CTD |
PMID:15983997 |
|
NCBI chr 1:207,500,959...207,508,276
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 protein] |
CTD |
PMID:7476933 |
|
NCBI chr20:3,626,685...3,629,303
|
|
G |
Vdac1 |
voltage-dependent anion channel 1 |
affects binding |
EXP |
Ethylmaleimide binds to VDAC1 protein |
CTD |
PMID:20192921 |
|
NCBI chr10:37,029,377...37,060,542
|
|
G |
Vkorc1 |
vitamin K epoxide reductase complex, subunit 1 |
multiple interactions decreases activity |
EXP |
Dithiothreitol promotes the reaction [Ethylmaleimide results in decreased activity of VKORC1 protein] |
CTD |
PMID:2319331 |
|
NCBI chr 1:191,932,969...191,935,490
|
|