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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:menaquinone-7
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Accession:CHEBI:44245 term browser browse the term
Definition:A menaquinone whose side-chain contains seven isoprene units in an all-trans-configutation.
Synonyms:exact_synonym: 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione
 related_synonym: (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosahept-aenyl)-3-methyl-1,4-naphthoquinone;   (all-E)-2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione;   Formula=C46H64O2;   InChI=1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+;   InChIKey=RAKQPZMEYJZGPI-LJWNYQGCSA-N;   MK-7;   SMILES=CC(C)=CCC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC\\C(C)=C\\CC1=C(C)C(=O)c2ccccc2C1=O;   vitamin K2(35);   vitamin MK 7
 xref: AGR:IND606538604;   AGR:IND606948745;   AGR:IND607052678;   Beilstein:2343160;   CAS:2124-57-4;   DrugBank:DB13075
 xref_mesh: MESH:C062629
 xref: MetaCyc:CPD-9718;   PDBeChem:MQ7;   PMID:13946233;   PMID:2153497;   PMID:24173914;   PMID:24174310;   PMID:24296867;   PMID:24453233;   PMID:31054684;   PMID:31152205;   PMID:31250633;   PMID:31579595;   PMID:32009201;   PMID:32109677;   PMID:32737601;   PMID:32952745;   PMID:33030563;   PMID:33090426;   PMID:33133563;   PMID:33233274;   PMID:33502649;   PMID:33574019;   PMID:33585456;   PMID:33664429;   PMID:33755417;   PMID:34029943;   PMID:34115006;   Reaxys:2343160


show annotations for term's descendants           Sort by:
menaquinone-7 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bglap bone gamma-carboxyglutamate protein multiple interactions
increases carboxylation		 ISO Warfarin inhibits the reaction [menaquinone 7 results in increased carboxylation of BGLAP protein] CTD PMID:31173816 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B increases expression ISO menaquinone 7 results in increased expression of TNFRSF11B mRNA CTD PMID:31173816 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      biological role 19852
        biochemical role 19582
          cofactor 16588
            menaquinone-7 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    p-block element atom 19849
                      carbon group element atom 19766
                        carbon atom 19785
                          organic molecular entity 19785
                            heteroorganic entity 19541
                              organochalcogen compound 19301
                                organooxygen compound 19193
                                  carbonyl compound 18937
                                    ketone 17268
                                      cyclic ketone 15920
                                        quinone 9904
                                          p-quinones 8556
                                            prenylquinone 151
                                              prenylnaphthoquinone 30
                                                menaquinones 30
                                                  menaquinone 30
                                                    menaquinone-7 2
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