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G |
A2m |
alpha-2-macroglobulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of PZP mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of A2M mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ABCA1 mRNA; Glucose results in decreased expression of ABCA1 protein morroniside inhibits the reaction [Glucose results in decreased expression of ABCA1 mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of ABCA1 protein] |
CTD |
PMID:34485530 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression |
ISO |
Glucose results in decreased expression of ABCB1 protein |
CTD |
PMID:22363694 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ABCB4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcb7 |
ATP binding cassette subfamily B member 7 |
decreases expression |
ISO |
Glucose results in decreased expression of ABCB7 mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:69,295,598...69,436,775
Ensembl chr X:69,295,552...69,436,858
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Daunorubicin]]; Glucose inhibits the reaction [Sodium Azide inhibits the reaction [ABCC1 protein results in decreased uptake of Etoposide]] |
CTD |
PMID:10856430 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Furosemide results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [sulfanitran results in increased activity of ABCC2 protein] promotes the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione] |
CTD |
PMID:19782883 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcd2 |
ATP binding cassette subfamily D member 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ABCD2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ABCG1 mRNA; Glucose results in decreased expression of ABCG1 protein morroniside inhibits the reaction [Glucose results in decreased expression of ABCG1 mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of ABCG1 protein] |
CTD |
PMID:34485530 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions decreases expression increases expression decreases phosphorylation |
ISO EXP |
[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA; [Pyruvic Acid co-treated with Glucose] results in increased phosphorylation of ACACA protein; PRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]]; SIRT1 protein inhibits the reaction [Glucose results in decreased phosphorylation of ACACA protein]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of ACACA mRNA] Glucose results in decreased expression of ACACA protein modified form Glucose results in increased expression of ACACA mRNA |
CTD |
PMID:15066988 PMID:18482975 PMID:19071085 PMID:19724016 PMID:24349266 PMID:33838154 More...
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
multiple interactions decreases phosphorylation |
ISO |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [ACACB protein affects the reaction [Glucose results in decreased expression of PPARGC1A protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [ACACB protein affects the reaction [Glucose results in decreased expression of SIRT1 protein]]; ACACB protein affects the reaction [Glucose results in decreased expression of NPHS1 protein]; ACACB protein affects the reaction [Glucose results in decreased expression of PPARGC1A protein]; ACACB protein affects the reaction [Glucose results in decreased expression of SIRT1 protein]; ACACB protein affects the reaction [Glucose results in decreased expression of SLC2A4 protein]; ACACB protein affects the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; ACACB protein affects the reaction [Glucose results in decreased phosphorylation of IRS1 protein] Glucose results in decreased phosphorylation of ACACB protein |
CTD |
PMID:33957017 |
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NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
multiple interactions |
ISO |
[Glucose co-treated with Palmitic Acid] results in decreased expression of ACADL mRNA |
CTD |
PMID:39265716 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadsb |
acyl-CoA dehydrogenase, short/branched chain |
multiple interactions |
ISO |
2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of ACADSB mRNA] |
CTD |
PMID:32613381 |
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NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379
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G |
Ace |
angiotensin I converting enzyme |
increases expression multiple interactions decreases expression |
ISO EXP |
Glucose results in increased expression of ACE protein Enalaprilat inhibits the reaction [Glucose results in increased expression of ACE protein] Glucose results in decreased expression of ACE mRNA CEBPB protein inhibits the reaction [Glucose results in increased expression of ACE protein] Glucose results in increased expression of ACE mRNA NFE2L2 protein affects the reaction [Glucose results in increased expression of ACE mRNA]; oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]]; trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA] |
CTD |
PMID:16452552 PMID:29211853 PMID:29266779 PMID:31655124 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
multiple interactions decreases expression |
EXP ISO |
NFE2L2 protein affects the reaction [Glucose results in decreased expression of ACE2 mRNA]; oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA]]; trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA] CEBPB protein inhibits the reaction [Glucose results in decreased expression of ACE2 protein]; Glucose inhibits the reaction [CEBPB protein binds to ACE2 promoter]; Valsartan inhibits the reaction [Glucose results in decreased expression of ACE2 protein] |
CTD |
PMID:29211853 PMID:29266779 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Ache |
acetylcholinesterase |
multiple interactions decreases activity |
ISO |
Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein] |
CTD |
PMID:26163454 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acly |
ATP citrate lyase |
increases expression |
EXP ISO |
Glucose results in increased expression of ACLY mRNA Glucose deficiency results in increased expression of ACLY mRNA; Glucose deficiency results in increased expression of ACLY protein |
CTD |
PMID:24349266 PMID:26811028 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Aco1 |
aconitase 1 |
multiple interactions increases expression |
EXP ISO |
[Oxygen deficiency co-treated with Glucose deficiency] affects the activity of ACO1 protein; Oxygen inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the activity of ACO1 protein] Glucose results in increased expression of ACO1 protein |
CTD |
PMID:16135072 PMID:38483099 |
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NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Aco2 |
aconitase 2 |
multiple interactions |
EXP |
[Glucose co-treated with Oxygen] affects the activity of ACO2 protein; Glucose results in decreased expression of and results in decreased activity of ACO2 protein; LONP1 protein affects the reaction [SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein]]; manganese tetrakis-(N-ethyl-2 pyridyl) porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Glucose co-treated with Oxygen] affects the activity of ACO2 protein]; SRT1720 inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of ACO2 protein] |
CTD |
PMID:11520895 PMID:31639451 |
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NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ACOT1 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 PMID:37567420 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox1 |
acyl-CoA oxidase 1 |
increases expression decreases expression multiple interactions |
ISO |
Glucose results in increased expression of ACOX1 mRNA Glucose results in decreased expression of ACOX1 protein [Glucose co-treated with Palmitic Acid] results in decreased expression of ACOX1 mRNA; Ditiocarb inhibits the reaction [YY1 protein inhibits the reaction [jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of ACOX1 protein]]]]; Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of ACOX1 protein]; jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of ACOX1 protein]]; YY1 protein inhibits the reaction [jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of ACOX1 protein]]] |
CTD |
PMID:36156098 PMID:39059604 PMID:39265716 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucose results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acsbg1 |
acyl-CoA synthetase bubblegum family member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ACSBG1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Glucose co-treated with Palmitic Acid] results in decreased expression of ACSL1 mRNA |
CTD |
PMID:39265716 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
EXP |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ACSL4 protein; qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ACSL4 protein] |
CTD |
PMID:36806343 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Acsm2 |
acyl-CoA synthetase medium-chain family member 2 |
increases expression |
ISO |
Glucose results in increased expression of ACSM2 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
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G |
Acsm3 |
acyl-CoA synthetase medium-chain family member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ACSM3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
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G |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
increases expression |
ISO |
Glucose results in increased expression of ACSS1 mRNA |
CTD |
PMID:36156098 |
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NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucose results in increased expression of ACSS2 mRNA |
CTD |
PMID:36156098 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Acta1 |
actin, alpha 1, skeletal muscle |
increases expression multiple interactions decreases expression |
EXP ISO |
Glucose results in increased expression of ACTA1 mRNA HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]] [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ACTA1 mRNA; fucoxanthin inhibits the reaction [Glucose results in decreased expression of ACTA1 mRNA] |
CTD |
PMID:24810525 PMID:33448797 PMID:37567420 |
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NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO EXP |
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; [Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in increased expression of ACTA2 protein]; MAPK14 protein promotes the reaction [Glucose results in increased expression of ACTA2 protein] Glucose results in increased expression of ACTA2 mRNA; Glucose results in increased expression of ACTA2 protein cinnamaldehyde inhibits the reaction [Glucose results in increased expression of ACTA2 protein] |
CTD |
PMID:20060012 PMID:21829520 PMID:26045780 PMID:29163160 PMID:35961541 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actb |
actin, beta |
decreases expression |
ISO |
Glucose deficiency results in decreased expression of ACTB protein |
CTD |
PMID:22314686 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Actg1 |
actin, gamma 1 |
multiple interactions |
EXP |
ACTG1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 Ensembl chr 3:105,619,737...105,624,232
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G |
Actr2 |
actin related protein 2 |
multiple interactions decreases expression |
ISO |
Eucalyptol inhibits the reaction [Glucose results in decreased expression of ACTR2 protein] |
CTD |
PMID:31483951 |
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NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
decreases expression |
ISO |
Glucose results in decreased expression of ADAM17 mRNA |
CTD |
PMID:31655124 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ADAM19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105
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G |
Adam32 |
ADAM metallopeptidase domain 32 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ADAM32 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161
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G |
Adam7 |
ADAM metallopeptidase domain 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of ADAM7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201
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G |
Adam8 |
ADAM metallopeptidase domain 8 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ADAM8 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADAM8 mRNA |
CTD |
PMID:17178593 PMID:37567420 |
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NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
increases expression |
ISO |
Glucose results in increased expression of ADAMTS1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adcy7 |
adenylate cyclase 7 |
decreases methylation multiple interactions increases expression |
ISO |
Glucose results in decreased methylation of ADCY7 gene fucoxanthin inhibits the reaction [Glucose results in decreased methylation of ADCY7 gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of ADCY7 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
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G |
Adgra1 |
adhesion G protein-coupled receptor A1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRA1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:194,629,744...194,673,254
Ensembl chr 1:194,629,726...194,672,550
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G |
Adgrb1 |
adhesion G protein-coupled receptor B1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRB1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902
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G |
Adgre4 |
adhesion G protein-coupled receptor E4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADGRE4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
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G |
Adgrf4 |
adhesion G protein-coupled receptor F4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ADGRF4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:18,272,050...18,303,219
Ensembl chr 9:18,272,050...18,303,217
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G |
Adgrg4 |
adhesion G protein-coupled receptor G4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ADGRG4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:134,734,610...134,864,449
Ensembl chr X:134,854,736...134,864,449
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G |
Adhfe1 |
alcohol dehydrogenase, iron containing, 1 |
decreases expression |
ISO |
Glucose results in decreased expression of ADHFE1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression increases expression multiple interactions increases secretion |
EXP ISO |
Glucose results in decreased expression of ADIPOQ protein Glucose results in increased expression of ADIPOQ protein [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA; [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; butylbenzyl phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Diethylhexyl Phthalate promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; tributyltin promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] Glucose deficiency results in increased secretion of ADIPOQ protein ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein]; argan oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein]; Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] |
CTD |
PMID:21912612 PMID:24802182 PMID:29165388 PMID:32407875 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor1 |
adiponectin receptor 1 |
multiple interactions decreases expression |
EXP |
FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]; FOXO1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]]; FOXO1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]]; Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; Resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein] Glucose results in decreased expression of ADIPOR1 mRNA; Glucose results in decreased expression of ADIPOR1 protein |
CTD |
PMID:24413998 |
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NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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G |
Adipor2 |
adiponectin receptor 2 |
multiple interactions decreases expression |
EXP |
ADIPOQ protein inhibits the reaction [Glucose results in decreased expression of ADIPOR2 protein] |
CTD |
PMID:21912612 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Adra1a |
adrenoceptor alpha 1A |
multiple interactions |
EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose]; [cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased transport of Glucose; Prazosin inhibits the reaction [[cirazoline results in increased activity of ADRA1A protein] which results in increased transport of Glucose] |
CTD |
PMID:15550506 |
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NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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G |
Adrb2 |
adrenoceptor beta 2 |
multiple interactions |
ISO |
[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose; [Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose; ICI 118551 inhibits the reaction [[BRL 37344 binds to and results in increased activity of ADRB2 protein] which results in increased uptake of Glucose]; ICI 118551 inhibits the reaction [[Clenbuterol binds to and results in increased activity of ADRB2 protein] which results in decreased uptake of Glucose] |
CTD |
PMID:18552870 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Adrb3 |
adrenoceptor beta 3 |
multiple interactions |
ISO |
[BRL 37344 binds to and results in increased activity of ADRB3 protein] which results in decreased abundance of Glucose; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ADRB3 mRNA |
CTD |
PMID:20930473 PMID:37567420 |
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NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucose results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agbl4 |
AGBL carboxypeptidase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AGBL4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions increases expression |
ISO EXP |
GLO1 inhibits the reaction [Glucose promotes the reaction [RELA protein binds to AGER promoter]]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER protein]; Glucose promotes the reaction [RELA protein binds to AGER promoter]; Luteolin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; RELA promotes the reaction [Glucose results in increased expression of AGER mRNA]; Rutin inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; SOD2 inhibits the reaction [Glucose results in increased expression of AGER protein]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; UCP1 inhibits the reaction [Glucose results in increased expression of AGER protein] [Ribose co-treated with Glucose] results in increased expression of AGER protein; AGER protein affects the reaction [Ribose promotes the reaction [Glucose results in increased phosphorylation of RELA protein]] Glucose results in increased expression of AGER mRNA; Glucose results in increased expression of AGER protein AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]] |
CTD |
PMID:19557821 PMID:19759273 PMID:19833897 PMID:22467055 PMID:30101366 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agl |
amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase |
increases uptake |
ISO |
AGL protein results in increased uptake of Glucose |
CTD |
PMID:24700805 |
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NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828
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G |
Agt |
angiotensinogen |
multiple interactions increases expression affects metabolic processing |
ISO EXP |
(3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Enalaprilat inhibits the reaction [Glucose results in increased expression of AGT protein]; Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of FOSL1 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]; Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]; Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]; Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]]; Simvastatin promotes the reaction [Glucose promotes the reaction [AGT protein results in increased expression of PTGS2 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of KLF10 mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of LIF mRNA]]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose results in increased expression of AGT mRNA]; 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Glucose results in increased expression of AGT protein]; alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT mRNA]; alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT protein]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT mRNA]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT protein]; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT mRNA]; Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of AGT mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of AGT protein]; NFE2L2 protein affects the reaction [Glucose results in increased expression of AGT mRNA]; oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of AGT mRNA]]; Rotenone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Rotenone inhibits the reaction [Glucose results in increased expression of AGT protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of AGT protein]; Taurine inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Taurine inhibits the reaction [Glucose results in increased expression of AGT protein]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Thenoyltrifluoroacetone inhibits the reaction [Glucose results in increased expression of AGT protein]; trigonelline inhibits the reaction [Glucose results in increased expression of AGT mRNA]; Valsartan promotes the reaction [Glucose results in increased expression of AGT protein] AGT protein affects the metabolism of Glucose Glucose results in increased expression of AGT mRNA; Glucose results in increased expression of AGT protein |
CTD |
PMID:11115780 PMID:12130563 PMID:15677497 PMID:16452552 PMID:19225232 PMID:19861503 PMID:29211853 More...
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of AGTR1 mRNA; Glucose results in increased expression of AGTR1 protein Enalaprilat inhibits the reaction [Glucose results in increased expression of AGTR1 protein] CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein] |
CTD |
PMID:16452552 PMID:29266779 PMID:31655124 PMID:34464088 |
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NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions increases expression |
ISO |
CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR2 protein] |
CTD |
PMID:29266779 |
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NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions increases response to substance |
ISO |
4,7-phenanthroline inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]]; AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]; alpha-naphthoflavone inhibits the reaction [AHR promotes the reaction [Tetrachlorodibenzodioxin results in decreased uptake of Glucose]] AHR protein promotes the reaction [Tetrachlorodibenzodioxin affects the susceptibility to Glucose] AHR results in increased susceptibility to Glucose |
CTD |
PMID:8738555 PMID:19623578 PMID:21849270 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aif1 |
allograft inflammatory factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of AIF1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
affects localization multiple interactions |
EXP |
Glucose affects the localization of AIFM1 protein Quercetin affects the reaction [Glucose affects the localization of AIFM1 protein]; sesamin affects the reaction [Glucose affects the localization of AIFM1 protein] |
CTD |
PMID:19146853 PMID:22524206 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Ak8 |
adenylate kinase 8 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of AK8 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 3:12,028,895...12,144,468
Ensembl chr 3:12,028,954...12,144,465
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G |
Akap5 |
A-kinase anchoring protein 5 |
increases expression |
ISO |
Glucose results in increased expression of AKAP5 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
multiple interactions decreases expression |
ISO |
fidarestat inhibits the reaction [Glucose results in decreased expression of AKR1A1 mRNA] |
CTD |
PMID:16805838 |
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NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
multiple interactions increases expression |
ISO |
AKR1B1 protein promotes the reaction [Glucose results in increased abundance of Sorbitol] Glucose results in increased expression of AKR1B1 mRNA; Glucose results in increased expression of AKR1B1 protein |
CTD |
PMID:16805838 PMID:25451566 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of AKR1C6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions increases response to substance decreases expression decreases phosphorylation increases expression |
ISO EXP |
Glucose results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; [Glucose affects the susceptibility to INS protein] which affects the phosphorylation of AKT1 protein; [Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein; ACACB protein affects the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein]; Berberine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Captopril inhibits the reaction [Glucose results in increased expression of AKT1 mRNA]; Fluorometholone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]; HAGLR protein affects the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; HAGLR protein inhibits the reaction [MIR106B inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; huai qi huang inhibits the reaction [Glucose results in increased expression of AKT1 mRNA]; Metformin inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; MIR106B inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose inhibits the reaction [INS protein results in increased phosphorylation of AKT1 protein]]; PTEN protein affects the reaction [HAGLR protein affects the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Rosiglitazone inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; spiraeoside inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; zhenwu decoction inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein] AKT1 protein mutant form results in increased susceptibility to Glucose deficiency 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[Glucose co-treated with Calcitriol] results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein; [Glucose co-treated with Calcitriol] results in increased phosphorylation of AKT1 protein; AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; AKT1 protein modified form inhibits the reaction [arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]]; AKT1 protein modified form inhibits the reaction [monomethylarsonous acid inhibits the reaction [INS1 protein results in increased uptake of Glucose]]; AKT1 protein promotes the reaction [Glucose affects the phosphorylation of and affects the activity of FOXO3 protein]; Bezafibrate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; Glucose affects the phosphorylation of and affects the activity of AKT1 protein; methyl pyruvate inhibits the reaction [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency]; PRKAA2 protein affects the reaction [AICA ribonucleotide inhibits the reaction [AKT1 protein mutant form affects the susceptibility to Glucose deficiency]]; SMARCA4A protein inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein] Glucose results in decreased expression of AKT1 protein modified form 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; [3,4-Dihydroxyphenylacetic Acid co-treated with Glucose] results in increased phosphorylation of AKT1 protein; [Catechin co-treated with Glucose] results in increased phosphorylation of AKT1 protein; [Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; Simvastatin inhibits the reaction [Glucose results in decreased expression of AKT1 protein modified form] |
CTD |
PMID:15806154 PMID:16385087 PMID:17520061 PMID:18004065 PMID:20370652 PMID:21031461 PMID:21333731 PMID:21803128 PMID:23159718 PMID:23453443 PMID:23954465 PMID:24946264 PMID:24971582 PMID:25471227 PMID:26054749 PMID:27049278 PMID:29981789 PMID:30914352 PMID:32602595 PMID:33270355 PMID:33450223 PMID:33957017 PMID:35264022 PMID:37523837 PMID:38088496 PMID:38115276 More...
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
affects response to substance |
ISO |
AKT2 protein affects the susceptibility to Glucose |
CTD |
PMID:21964073 |
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NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alb |
albumin |
multiple interactions increases metabolic processing decreases uptake |
ISO EXP |
[Fructose co-treated with Glucose] results in increased glycation of ALB protein; [Peroxynitrous Acid co-treated with Glucose] results in increased glycation of ALB protein; Phlorhizin inhibits the reaction [Glucose results in decreased uptake of ALB protein]; pimagedine inhibits the reaction [[Fructose co-treated with Glucose] results in increased glycation of ALB protein]; pimagedine inhibits the reaction [[Peroxynitrous Acid co-treated with Glucose] results in increased glycation of ALB protein]; ursonic acid inhibits the reaction [[Fructose co-treated with Glucose] results in increased glycation of ALB protein] Glucose results in increased metabolism of ALB protein [Glucose deficiency co-treated with ALB protein] results in decreased expression of FABP4 mRNA; [Glucose deficiency co-treated with ALB protein] results in decreased expression of PCK1 mRNA ALB protein modified form inhibits the reaction [Glucose results in increased phosphorylation of RELA protein]; ALB protein modified form inhibits the reaction [Glucose results in increased secretion of INS1 protein]; MK615 extract inhibits the reaction [ALB protein modified form inhibits the reaction [Glucose results in increased phosphorylation of RELA protein]]; MK615 extract inhibits the reaction [ALB protein modified form inhibits the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:8536680 PMID:12196478 PMID:12434198 PMID:16313995 PMID:27415824 PMID:36933777 More...
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alcam |
activated leukocyte cell adhesion molecule |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of ALCAM mRNA] |
CTD |
PMID:33448797 |
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NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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G |
Aldh1b1 |
aldehyde dehydrogenase 1 family, member B1 |
increases expression |
ISO |
Glucose deficiency results in increased expression of ALDH1B1 protein |
CTD |
PMID:22314686 |
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NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
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G |
Aldh1l2 |
aldehyde dehydrogenase 1 family, member L2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of ALDH1L2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:20,254,246...20,305,793
Ensembl chr 7:20,254,233...20,305,776
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
decreases expression multiple interactions |
EXP |
Glucose results in decreased expression of ALDH2 protein N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ALDH2 protein] |
CTD |
PMID:29128638 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldh3b3 |
aldehyde dehydrogenase 3 family, member B3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALDH3B3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:201,193,832...201,201,666
Ensembl chr 1:201,187,962...201,250,204
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G |
Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
decreases expression |
ISO |
Glucose results in decreased expression of ALDH6A1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucose results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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G |
Alk |
ALK receptor tyrosine kinase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ALK mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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G |
Alox12 |
arachidonate 12-lipoxygenase, 12S type |
increases expression |
ISO |
Glucose results in increased expression of ALOX12 mRNA |
CTD |
PMID:32942007 |
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NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions increases expression |
EXP ISO |
[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein; caffeic acid inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; Edaravone inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein]; SB 203580 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] affects the localization of ALOX5 protein] Glucose results in increased expression of ALOX5 mRNA |
CTD |
PMID:18951527 PMID:31655124 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Alpk3 |
alpha-kinase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ALPK3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression multiple interactions |
ISO EXP |
Glucose results in decreased expression of ALPL mRNA 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]] morroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA] |
CTD |
PMID:32643284 PMID:33450223 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Amer2 |
APC membrane recruitment protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AMER2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:34,525,352...34,535,660
Ensembl chr15:34,524,542...34,528,455
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G |
Amot |
angiomotin |
decreases expression |
ISO |
Glucose results in decreased expression of AMOT mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:108,982,399...109,041,265
Ensembl chr X:108,984,022...109,041,272
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G |
Angptl4 |
angiopoietin-like 4 |
increases expression |
ISO |
Glucose results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:16805838 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ankrd61 |
ankyrin repeat domain 61 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ANKRD61 mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of ANKRD61 mRNA] |
CTD |
PMID:31525975 PMID:33448797 |
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NCBI chr12:10,718,908...10,723,267
Ensembl chr12:10,718,908...10,723,265
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G |
Anks1b |
ankyrin repeat and sterile alpha motif domain containing 1B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ANKS1B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693
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G |
Anxa5 |
annexin A5 |
decreases expression |
ISO |
Glucose results in decreased expression of ANXA5 mRNA |
CTD |
PMID:31655124 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Aoc1 |
amine oxidase, copper containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of AOC1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AOC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of APAF1 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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G |
Apc |
APC regulator of WNT signaling pathway |
decreases expression |
EXP |
Glucose results in decreased expression of APC mRNA |
CTD |
PMID:21818840 |
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NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
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G |
Apcs |
amyloid P component, serum |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of APCS mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
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G |
Apoa1 |
apolipoprotein A1 |
increases expression decreases expression |
EXP |
Glucose results in increased expression of APOA1 mRNA; Glucose results in increased expression of APOA1 protein Glucose results in decreased expression of APOA1 mRNA |
CTD |
PMID:9322794 PMID:9668074 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apob |
apolipoprotein B |
multiple interactions |
ISO |
Glucose promotes the reaction [Copper Sulfate results in increased cleavage of APOB protein] |
CTD |
PMID:19489629 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
affects secretion multiple interactions decreases expression |
ISO |
Glucose deficiency affects the secretion of APOE protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of APOE mRNA; morroniside inhibits the reaction [Glucose results in decreased expression of APOE mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of APOE protein] Glucose results in decreased expression of APOE mRNA; Glucose results in decreased expression of APOE protein |
CTD |
PMID:24802182 PMID:34485530 PMID:37567420 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Apol9a |
apolipoprotein L9a |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of APOL9A mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:109,140,871...109,149,799
Ensembl chr 7:109,140,871...109,147,649
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G |
App |
amyloid beta precursor protein |
multiple interactions increases abundance |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form co-treated with PF-06840003] results in decreased abundance of Glucose; [APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Glucose; IDO1 protein affects the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in increased abundance of Glucose] PF-06840003 inhibits the reaction [APP protein mutant form results in increased abundance of Glucose] |
CTD |
PMID:39172838 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp1 |
aquaporin 1 |
increases expression multiple interactions |
EXP |
Glucose results in increased expression of AQP1 mRNA benazepril inhibits the reaction [Glucose results in increased expression of AQP1 mRNA]; valsartan inhibits the reaction [Glucose results in increased expression of AQP1 mRNA] |
CTD |
PMID:11510275 |
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NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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G |
Aqp3 |
aquaporin 3 (Gill blood group) |
multiple interactions increases expression |
ISO |
Glucose promotes the reaction [AQP3 protein results in increased transport of Glycerol] Glucose results in increased expression of AQP3 mRNA; Glucose results in increased expression of AQP3 protein |
CTD |
PMID:12234316 |
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NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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G |
Aqp4 |
aquaporin 4 |
multiple interactions increases expression |
EXP |
benazepril inhibits the reaction [Glucose results in increased expression of AQP4 mRNA]; valsartan inhibits the reaction [Glucose results in increased expression of AQP4 mRNA] |
CTD |
PMID:11510275 |
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NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856
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G |
Aqp5 |
aquaporin 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of AQP5 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of AQP5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
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G |
Aqp8 |
aquaporin 8 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AQP8 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:177,993,313...177,999,158
Ensembl chr 1:177,993,305...177,999,158
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G |
Ar |
androgen receptor |
multiple interactions |
EXP ISO |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of AR mRNA; tetrahydropalmatine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of AR mRNA] [2,4-Dichlorophenoxyacetic Acid co-treated with Glyphosate co-treated with lard co-treated with Cholesterol co-treated with Glucose co-treated with Sucrose co-treated with Fructose] results in decreased expression of AR protein |
CTD |
PMID:37606869 PMID:37615203 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of AREG mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arg2 |
arginase 2 |
increases expression |
ISO |
Glucose results in increased expression of ARG2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378
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G |
Arhgap6 |
Rho GTPase activating protein 6 |
increases expression |
ISO |
Glucose results in increased expression of ARHGAP6 mRNA |
CTD |
PMID:31525975 |
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NCBI chr X:24,953,464...25,490,003
Ensembl chr X:24,953,464...25,488,663
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G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ARHGDIB mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of ARHGDIB mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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G |
Arl4d |
ARF like GTPase 4D |
multiple interactions |
EXP |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ARL4D mRNA; ARL4D protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr10:86,592,054...86,602,843
Ensembl chr10:86,595,661...86,602,836
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G |
Arl5b |
ARF like GTPase 5B |
increases expression |
ISO |
Glucose results in increased expression of ARL5B mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854
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G |
Arl5c |
ARF like GTPase 5C |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of ARL5C mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:82,985,213...82,993,425
Ensembl chr10:82,985,216...82,992,002
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G |
Armcx6 |
armadillo repeat containing, X-linked 6 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of ARMCX6 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr X:97,929,032...97,932,031
Ensembl chr X:97,929,041...97,931,977
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions increases activity |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA; Glucose promotes the reaction [[ARNT protein binds to G6PC1 promoter] which results in increased expression of G6PC1 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of ARNT mRNA] [Glucose co-treated with Oxygen deficiency] inhibits the reaction [ARNT protein binds to HIF1A protein] Glucose results in increased activity of ARNT protein |
CTD |
PMID:15767253 PMID:18227068 PMID:33962019 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Arsj |
arylsulfatase family, member J |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of ARSJ mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:214,774,631...214,854,614
Ensembl chr 2:214,774,654...214,854,612
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G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ASCL1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
affects expression |
ISO |
Glucose affects the expression of ASNS mRNA |
CTD |
PMID:17409444 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Aspg |
asparaginase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of ASPG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268
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G |
Aspn |
asporin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of ASPN mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
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G |
Atad1 |
ATPase family, AAA domain containing 1 |
multiple interactions |
EXP |
ATAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of ATF3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression increases response to substance multiple interactions |
ISO EXP |
Glucose deficiency results in increased expression of ATF4 mRNA ATF4 protein results in increased susceptibility to Glucose Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ATF4 protein] Glucose deficiency results in increased expression of ATF4 protein 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein]; [Galactose co-treated with Glucose deficiency] promotes the reaction [Leflunomide results in increased expression of ATF4 protein]; salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF4 protein]] |
CTD |
PMID:27226639 PMID:27278863 PMID:29427785 PMID:31022492 PMID:34801538 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
increases expression multiple interactions |
ISO EXP |
Glucose deficiency results in increased expression of ATF6 protein Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ATF6 protein]; Glucose results in increased expression of and affects the localization of ATF6 protein; Metformin inhibits the reaction [Glucose results in increased expression of and affects the localization of ATF6 protein] 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of ATF6 protein]; ATF6 protein modified form promotes the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased expression of HSPA5 protein]] |
CTD |
PMID:31022492 PMID:34801538 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg10 |
autophagy related 10 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ATG10 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of ATG10 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
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G |
Atg3 |
autophagy related 3 |
increases expression |
EXP |
Glucose results in increased expression of ATG3 mRNA |
CTD |
PMID:38444079 |
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NCBI chr11:55,624,914...55,653,249
Ensembl chr11:55,624,917...55,653,224
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G |
Atg5 |
autophagy related 5 |
multiple interactions increases expression decreases expression |
EXP |
3-methyladenine inhibits the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]]; [Glucose co-treated with Lycopene] results in increased expression of ATG5 mRNA; N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]; Sirolimus promotes the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]]; ULK1 protein affects the reaction [Glucose results in decreased expression of ATG5 protein]; ULK1 protein affects the reaction [N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide inhibits the reaction [Glucose results in decreased expression of ATG5 protein]] Glucose results in increased expression of ATG5 mRNA |
CTD |
PMID:29128638 PMID:38444079 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
multiple interactions decreases expression |
EXP |
Inositol inhibits the reaction [Glucose results in decreased expression of ATG7 protein] |
CTD |
PMID:35243728 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Atl1 |
atlastin GTPase 1 |
multiple interactions |
EXP |
ATL1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 6:88,377,168...88,475,242
Ensembl chr 6:88,377,239...88,475,204
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G |
Atox1 |
antioxidant 1 copper chaperone |
increases expression |
ISO |
Glucose results in increased expression of ATOX1 mRNA |
CTD |
PMID:32942007 |
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NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
multiple interactions |
ISO EXP |
Glucose results in decreased expression of and results in decreased activity of ATP1A1 protein; INS protein inhibits the reaction [Glucose results in decreased expression of ATP1A1 protein] [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of and affects the localization of ATP1A1 protein; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of and affects the localization of ATP1A1 protein] |
CTD |
PMID:22162761 PMID:29702141 |
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NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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G |
Atp2a1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ATP2A1 mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of ATP2A1 mRNA] |
CTD |
PMID:31525975 PMID:33448797 |
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NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
multiple interactions |
EXP |
[Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] results in increased expression of ATP5F1A protein |
CTD |
PMID:25997894 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp5f1d |
ATP synthase F1 subunit delta |
multiple interactions |
EXP |
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein]]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of ATP5F1D protein] |
CTD |
PMID:25305180 |
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NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
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G |
Atp6ap2 |
ATPase H+ transporting accessory protein 2 |
increases expression multiple interactions |
EXP |
Glucose results in increased expression of ATP6AP2 mRNA; Glucose results in increased expression of ATP6AP2 protein N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Glucose results in increased expression of ATP6AP2 protein] |
CTD |
PMID:19861503 |
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NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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G |
Aurka |
aurora kinase A |
increases expression |
ISO |
Glucose results in increased expression of AURKA mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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G |
Azgp1 |
alpha-2-glycoprotein 1, zinc-binding |
affects secretion |
ISO |
Glucose deficiency affects the secretion of AZGP1 protein |
CTD |
PMID:24802182 |
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NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
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G |
B2m |
beta-2 microglobulin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of B2M mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
increases expression multiple interactions |
EXP |
Glucose results in increased expression of B3GAT3 mRNA [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA]; IL1B protein inhibits the reaction [Glucose results in increased expression of B3GAT3 mRNA] |
CTD |
PMID:11801247 |
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NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
B3gnt6 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of B3GNT6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:152,484,572...152,496,226
Ensembl chr 1:152,486,343...152,492,150
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G |
B4galnt4 |
beta-1,4-N-acetyl-galactosaminyl transferase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of B4GALNT4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:196,171,394...196,182,294
Ensembl chr 1:196,171,394...196,182,294
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions increases expression |
ISO EXP |
[resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein]; Glucose results in decreased phosphorylation of and results in decreased activity of BAD protein [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAD protein Glucose results in increased expression of BAD mRNA |
CTD |
PMID:17293559 PMID:20370652 PMID:38444079 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
EXP ISO |
[[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Carvedilol] which results in decreased expression of BAK1 mRNA Glucose results in increased expression of BAK1 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAK1 mRNA] |
CTD |
PMID:29122578 PMID:33962019 PMID:38444079 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bambi |
BMP and activin membrane-bound inhibitor |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of BAMBI mRNA] |
CTD |
PMID:33448797 |
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NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
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G |
Barx2 |
BARX homeobox 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of BARX2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013
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G |
Batf2 |
basic leucine zipper ATF-like transcription factor 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BATF2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:203,467,291...203,479,428
Ensembl chr 1:203,468,097...203,475,889
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions affects expression |
ISO EXP |
Glucose results in increased expression of BAX mRNA; Glucose results in increased expression of BAX protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased expression of BAX mRNA]; [Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of BAX protein; asiatic acid inhibits the reaction [Glucose results in increased expression of BAX mRNA]; Carnosine inhibits the reaction [Glucose results in increased expression of BAX mRNA]; diallyl trisulfide inhibits the reaction [Glucose results in increased expression of BAX protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BAX protein]; MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of BAX protein]]; MIR142 inhibits the reaction [Glucose results in increased expression of BAX protein]; MitoTEMPO inhibits the reaction [Glucose results in increased expression of BAX protein]; NDRG2 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; polyethylene glycol loxenatide inhibits the reaction [Glucose results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]; salvianolic acid inhibits the reaction [Glucose results in increased expression of BAX protein]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in increased expression of BAX protein]]; spiraeoside inhibits the reaction [Glucose results in increased expression of BAX protein]; TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of BAX protein] 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX mRNA]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX mRNA]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]; 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in increased expression of BAX protein]; [Glucose co-treated with Bupivacaine] results in increased expression of BAX protein; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX mRNA; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein modified form; CEBPB protein inhibits the reaction [Glucose results in increased expression of BAX protein]; gastrodin inhibits the reaction [Glucose results in increased expression of BAX protein]; HIF1A protein affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]; HIF1A protein affects the reaction [MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX mRNA]]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX mRNA]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]; MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]; MIR186 mRNA inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of BAX protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein]; Valsartan inhibits the reaction [Glucose results in increased expression of BAX protein] 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in increased expression of BAX protein]; [Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein; [morroniside co-treated with Diosgenin] inhibits the reaction [Glucose results in increased expression of BAX protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]]; cinnamic acid inhibits the reaction [Glucose results in increased expression of BAX protein]; Diosgenin inhibits the reaction [Glucose results in increased expression of BAX protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]]; gastrodin inhibits the reaction [Glucose results in increased expression of BAX protein]; Metformin inhibits the reaction [Glucose results in increased expression of BAX protein]; morroniside inhibits the reaction [Glucose results in increased expression of BAX protein]; naringenin inhibits the reaction [Glucose results in increased expression of BAX mRNA]; naringenin inhibits the reaction [Glucose results in increased expression of BAX protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased expression of BAX protein]; Quercetin affects the reaction [Glucose affects the expression of BAX protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of BAX protein]; Scopoletin inhibits the reaction [Glucose results in increased expression of BAX protein]; sesamin affects the reaction [Glucose affects the expression of BAX protein]; STIM1 protein affects the reaction [Glucose results in increased expression of BAX protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BAX protein] |
CTD |
PMID:21803128 PMID:22524206 PMID:23192364 PMID:23451161 PMID:24218232 PMID:24682241 PMID:25238743 PMID:25305180 PMID:26054749 PMID:27234048 PMID:28106847 PMID:28675767 PMID:28713934 PMID:29266779 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31323227 PMID:31672611 PMID:31935362 PMID:32602595 PMID:33508982 PMID:33759271 PMID:33764184 PMID:33962019 PMID:36462176 PMID:37417536 PMID:37619648 PMID:38069837 PMID:38124441 PMID:38444079 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA; [Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BBC3 mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of BBC3 mRNA] [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein modified form; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BBC3 protein] |
CTD |
PMID:24451382 PMID:28675767 PMID:33962019 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bche |
butyrylcholinesterase |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of BCHE mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bcl11a |
BCL11 transcription factor A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of BCL11A mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression affects expression multiple interactions |
ISO EXP |
Glucose results in decreased expression of BCL2 mRNA; Glucose results in decreased expression of BCL2 protein Glucose affects the expression of BCL2 mRNA; Glucose affects the expression of BCL2 protein 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; [Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; [Glucose co-treated with Lycopene] results in increased expression of BCL2 mRNA; [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; [morroniside co-treated with Diosgenin] inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of BCL2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; Chlorogenic Acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; cinnamic acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Diosgenin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; gastrodin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; morroniside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; naringenin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in decreased expression of BCL2 protein]; Quercetin affects the reaction [Glucose affects the expression of BCL2 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; Resveratrol inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Scopoletin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; sesamin affects the reaction [Glucose affects the expression of BCL2 protein]; STIM1 protein affects the reaction [Glucose results in decreased expression of BCL2 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA; [Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein; [Resveratrol co-treated with Glucose] results in increased expression of BCL2 protein; asiatic acid inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]; Berberine inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]; Catechin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; diallyl trisulfide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; epigallocatechin gallate inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; Gliclazide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]; Glucose results in increased degradation of and results in decreased expression of BCL2 protein; Luteolin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in decreased expression of BCL2 protein]; MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in decreased expression of BCL2 protein]]; MIR142 inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; MitoTEMPO inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; NS 1619 inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Quercetin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; Rutin inhibits the reaction [Glucose results in increased degradation of and results in decreased expression of BCL2 protein]; salvianolic acid inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in decreased expression of BCL2 protein]]; spiraeoside inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]]; TAOK1 mRNA alternative form affects the reaction [Glucose results in decreased expression of BCL2 protein] 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 mRNA]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 mRNA]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]; 8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one promotes the reaction [[Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein]; [Glucose co-treated with Bupivacaine] results in decreased expression of BCL2 protein; [Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 mRNA; [Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]]; gastrodin inhibits the reaction [Glucose results in decreased expression of BCL2 protein]; HIF1A protein affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]; HIF1A protein affects the reaction [MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 mRNA]]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 mRNA]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]; MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]; MIR186 mRNA inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of BCL2 protein]; MIR210 mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of BCL2 mRNA]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of BCL2 protein] |
CTD |
PMID:18088078 PMID:19557821 PMID:21413024 PMID:21803128 PMID:21818840 PMID:22467055 PMID:22524206 PMID:23108914 PMID:23192364 PMID:23637816 PMID:23954465 PMID:24218232 PMID:24349266 PMID:24682241 PMID:25305180 PMID:26054749 PMID:27234048 PMID:27481074 PMID:28106847 PMID:28713934 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31323227 PMID:31672611 PMID:31935362 PMID:32602595 PMID:33508982 PMID:33759271 PMID:33764184 PMID:33962019 PMID:34801538 PMID:36462176 PMID:37417536 PMID:37619648 PMID:38069837 PMID:38124441 PMID:38444079 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
EXP |
BCL2L1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein] |
CTD |
PMID:25471227 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl2l15 |
Bcl2-like 15 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BCL2L15 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 2:191,338,959...191,344,078
Ensembl chr 2:191,338,959...191,344,078
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G |
Bco1 |
beta-carotene oxygenase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of BCO1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
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G |
Bdkrb1 |
bradykinin receptor B1 |
increases expression multiple interactions |
EXP |
Glucose results in increased expression of BDKRB1 protein argan oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein]; Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] |
CTD |
PMID:29165388 |
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NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Becn1 |
beclin 1 |
multiple interactions increases expression decreases expression |
EXP ISO |
[Glucose co-treated with Lycopene] results in increased expression of BECN1 mRNA; [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in decreased expression of BECN1 protein]; [Resveratrol co-treated with Glucose] results in increased expression of BECN1 protein; Inositol inhibits the reaction [Glucose results in decreased expression of BECN1 protein] Glucose results in increased expression of BECN1 mRNA Glucose results in increased expression of BECN1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in increased expression of BECN1 protein]]; Calcitriol inhibits the reaction [Glucose results in increased expression of BECN1 protein]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in increased expression of BECN1 protein]]; HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein] |
CTD |
PMID:25997894 PMID:28713934 PMID:30459625 PMID:33450223 PMID:35243728 PMID:38444079 More...
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Begain |
brain-enriched guanylate kinase-associated |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of BEGAIN mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions decreases expression |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP protein]]; Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]]; Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]] morroniside inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of BGLAP protein] Glucose results in decreased expression of BGLAP mRNA; Glucose results in decreased expression of BGLAP protein |
CTD |
PMID:32643284 PMID:33450223 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of BHMT mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BID mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Bmp2 |
bone morphogenetic protein 2 |
decreases expression multiple interactions |
ISO EXP |
Glucose results in decreased expression of BMP2 mRNA cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of BMP2 mRNA]; tin mesoporphyrin promotes the reaction [Glucose results in decreased expression of BMP2 mRNA] morroniside inhibits the reaction [Glucose results in decreased expression of BMP2 mRNA] |
CTD |
PMID:19924377 PMID:32643284 |
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NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp8a |
bone morphogenetic protein 8a |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of BMP8B mRNA] |
CTD |
PMID:31525975 PMID:33448797 |
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NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
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G |
Bmper |
BMP-binding endothelial regulator |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BMPER mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256
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G |
Bnip3 |
BCL2 interacting protein 3 |
multiple interactions |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3 mRNA] |
CTD |
PMID:33962019 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bnip3l |
BCL2 interacting protein 3 like |
multiple interactions decreases expression |
ISO EXP |
[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of BNIP3L mRNA] Glucose results in decreased expression of BNIP3L protein Inositol inhibits the reaction [Glucose results in decreased expression of BNIP3L protein] |
CTD |
PMID:33962019 PMID:35243728 |
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NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
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G |
Bst2 |
bone marrow stromal cell antigen 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of BST2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
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G |
Btbd17 |
BTB domain containing 17 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of BTBD17 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:99,826,132...99,832,624
Ensembl chr10:99,826,132...99,832,624
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G |
C1qtnf3 |
C1q and TNF related 3 |
decreases expression |
ISO |
Glucose results in decreased expression of C1QTNF3 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
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G |
C1r |
complement C1r |
decreases secretion |
ISO |
Glucose deficiency results in decreased secretion of C1R protein |
CTD |
PMID:24802182 |
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NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
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G |
C1s |
complement C1s |
affects secretion |
ISO |
Glucose deficiency affects the secretion of C1S protein |
CTD |
PMID:24802182 |
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NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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G |
C3 |
complement C3 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of C3 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of C3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of C3 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of C3 mRNA |
CTD |
PMID:17178593 PMID:23199288 PMID:37567420 |
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NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C4b |
complement C4B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of C4B mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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G |
C5 |
complement C5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of HC mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of HC mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
C5ar1 |
complement C5a receptor 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of C5AR1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:76,948,622...76,959,826
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G |
Cabp4 |
calcium binding protein 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CABP4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:201,428,671...201,442,950
Ensembl chr 1:201,428,672...201,433,172
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G |
Cacna1s |
calcium voltage-gated channel subunit alpha1 S |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CACNA1S mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
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G |
Calca |
calcitonin-related polypeptide alpha |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CALCA mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CALCA mRNA |
CTD |
PMID:31655124 PMID:37567420 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Calm2 |
calmodulin 2 |
multiple interactions |
EXP |
CALM2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 Ensembl chr15:7,091,567...7,104,287
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucose results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Calu |
calumenin |
decreases secretion |
ISO |
Glucose deficiency results in decreased secretion of CALU protein |
CTD |
PMID:24802182 |
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NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
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G |
Caly |
calcyon neuron-specific vesicular protein |
multiple interactions |
EXP |
CALY protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551
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G |
Canx |
calnexin |
decreases expression multiple interactions increases expression |
ISO EXP |
Glucose results in decreased expression of CANX mRNA Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CANX protein] |
CTD |
PMID:17178593 PMID:34801538 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Capn1 |
calpain 1 |
multiple interactions increases expression |
EXP ISO |
2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside inhibits the reaction [[Oxygen co-treated with Glucose deficiency] results in increased expression of CAPN1 protein]; [Oxygen co-treated with Glucose deficiency] results in increased expression of CAPN1 protein Glucose results in increased expression of CAPN1 protein Furans analog inhibits the reaction [Glucose results in increased expression of CAPN1 protein] |
CTD |
PMID:24726522 PMID:28911973 |
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NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
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G |
Car3 |
carbonic anhydrase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CAR3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp1 |
caspase 1 |
multiple interactions increases activity increases expression increases cleavage |
ISO EXP |
Acetylcysteine inhibits the reaction [Glucose results in increased cleavage of CASP1 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP1 protein]; Glucose results in increased cleavage of and results in increased activity of CASP1 protein; Glucose results in increased expression of and results in increased cleavage of CASP1 protein Glucose results in increased activity of CASP1 mRNA; Glucose results in increased activity of CASP1 protein Glucose results in increased expression of CASP1 mRNA; Glucose results in increased expression of CASP1 protein [Glucose co-treated with TGFB1 protein] results in increased cleavage of CASP1 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein; Allopurinol inhibits the reaction [Glucose results in increased expression of CASP1 protein]; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased cleavage of CASP1 protein]; bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein]; Glucose results in increased expression of and results in increased cleavage of CASP1 protein; HAGLR protein affects the reaction [Glucose results in increased expression of and results in increased cleavage of CASP1 protein]; HAGLR protein promotes the reaction [Glucose results in increased expression of and results in increased cleavage of CASP1 protein]; L 709049 analog inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Lipopolysaccharides inhibits the reaction [swietenine inhibits the reaction [Glucose results in increased expression of CASP1 protein]]; Lipopolysaccharides promotes the reaction [Glucose results in increased expression of CASP1 protein]; loganin inhibits the reaction [Glucose results in increased expression of CASP1 mRNA]; loganin inhibits the reaction [Glucose results in increased expression of CASP1 protein]; MIR200C mRNA affects the reaction [Glucose results in increased cleavage of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [Glucose results in increased expression of CASP1 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide promotes the reaction [swietenine inhibits the reaction [Glucose results in increased expression of CASP1 protein]]; PTEN protein affects the reaction [HAGLR protein affects the reaction [Glucose results in increased expression of and results in increased cleavage of CASP1 protein]]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP1 protein]; SLC30A7 protein affects the reaction [MIR200C mRNA affects the reaction [Glucose results in increased cleavage of CASP1 protein]]; swietenine inhibits the reaction [Glucose results in increased expression of CASP1 protein]; TXNIP mRNA promotes the reaction [Glucose results in increased expression of CASP1 protein] [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein modified form; Allopurinol inhibits the reaction [Glucose results in increased expression of CASP1 protein]; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP1 protein modified form]; L 709049 analog inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP1 protein]; rhodioloside inhibits the reaction [Glucose results in increased expression of CASP1 protein]; Suramin inhibits the reaction [Glucose results in increased activity of CASP1 protein]; TXNIP mRNA promotes the reaction [Glucose results in increased expression of CASP1 protein] |
CTD |
PMID:20370652 PMID:21832250 PMID:23647015 PMID:27783111 PMID:29031534 PMID:34212273 PMID:35191607 PMID:35607288 PMID:35961541 PMID:36066211 PMID:37127800 PMID:37473909 PMID:38088496 More...
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions increases expression increases cleavage |
ISO EXP |
TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP12 protein]; waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP12 protein] Glucose results in increased expression of CASP12 protein Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of CASP12 protein] |
CTD |
PMID:30076216 PMID:34801538 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity increases expression increases cleavage decreases expression |
ISO EXP |
[Carnosine co-treated with asiatic acid] inhibits the reaction [Glucose results in increased activity of CASP3 protein]; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein; [Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form; [Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein; asiatic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Captopril inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; Carnosine inhibits the reaction [Glucose results in increased activity of CASP3 protein]; diallyl trisulfide inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Fluorometholone inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Gliclazide inhibits the reaction [Glucose results in increased expression of CASP3 protein]; huai qi huang inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of CASP3 protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 mRNA]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP3 protein]; MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased cleavage of CASP3 protein]]; MIR142 inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; MitoTEMPO inhibits the reaction [Glucose results in increased activity of CASP3 protein]; polyethylene glycol loxenatide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Glucose results in increased activity of CASP3 protein]; rutecarpine inhibits the reaction [Glucose results in increased activity of CASP3 protein]; salvianolic acid inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; SIRT1 protein inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased cleavage of CASP3 protein]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; TAOK1 mRNA alternative form affects the reaction [Glucose results in increased cleavage of CASP3 protein] Glucose results in increased expression of CASP3 mRNA; Glucose results in increased expression of CASP3 protein 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide inhibits the reaction [Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CASP3 mRNA]]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; 2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CASP3 mRNA]; [Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein; [Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CASP3 mRNA; [Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP3 protein]; gastrodin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein modified form]; Glucose results in increased cleavage of and results in increased activity of CASP3 protein; HIF1A protein affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; HIF1A protein affects the reaction [MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]]; INO 1001 inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]]; Isoflurane inhibits the reaction [2-(1,3-benzodioxol-5-yl)-N-(5-methyl-4-(1-(2-methylbenzoyl)-2,3-dihydroindol-5-yl)-1,3-thiazol-2-yl)acetamide promotes the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CASP3 mRNA]]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; Isoflurane inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CASP3 mRNA]; MIR144 mRNA promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; MIR186 mRNA affects the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; MIR186 mRNA inhibits the reaction [[Glucose deficiency co-treated with Oxygen deficiency] results in increased cleavage of CASP3 protein]; MIR322 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; SIRT7 protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; TRAF3 affects the reaction [Glucose results in increased cleavage of CASP3 protein]; TRPM7 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein]; VDAC1 protein inhibits the reaction [Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; VDAC1 protein promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; waixenicin A inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; zinc protoporphyrin inhibits the reaction [[Glucose deficiency co-treated with Simvastatin] results in increased cleavage of CASP3 protein] Glucose results in increased activity of CASP3; Glucose results in increased activity of CASP3 protein 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid inhibits the reaction [notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [2-chloro-N(6)cyclopentyladenosine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [LY 379268 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; 2-chloro-N(6)cyclopentyladenosine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; [Dithionite co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Glucose co-treated with Lycopene] results in increased expression of CASP3 mRNA; [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; [morroniside co-treated with Diosgenin] inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein; [Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] affects the expression of and affects the activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased cleavage of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Antigen-Antibody Complex inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Chlorogenic Acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; cinnamic acid inhibits the reaction [Glucose results in increased activity of CASP3 protein]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Diosgenin inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]; gastrodin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Glucose results in increased expression of and results in increased activity of CASP3 protein; Glucose results in increased expression of and results in increased cleavage of CASP3 protein; GSK3B protein inhibits the reaction [MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; HMOX1 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; IGF2R protein modified form inhibits the reaction [Glucose results in increased expression of CASP3 protein modified form]; IGF2R protein modified form inhibits the reaction [Glucose results in increased expression of CASP3 protein]; KEAP1 protein inhibits the reaction [diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; LY 379268 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Metformin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; Metformin inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; MIR135A mRNA inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; morroniside inhibits the reaction [Glucose results in increased expression of and results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased activity of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP3 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; NFE2L2 mutant form inhibits the reaction [diallyl trisulfide inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; NFE2L2 protein mutant form affects the reaction [plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; NFE2L2 protein promotes the reaction [diallyl trisulfide inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; NFE2L2 protein promotes the reaction [diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein modified form]]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased activity of CASP3 protein]; notoginsenoside R1 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein]; plumbagin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [[Dithionite co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Glucose results in increased expression of CASP3 protein modified form]; Scopoletin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; sesamin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Simvastatin inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; STIM1 protein affects the reaction [Glucose results in increased cleavage of CASP3 protein]; trigonelline inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]; U 0126 inhibits the reaction [2-chloro-N(6)cyclopentyladenosine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; U 0126 inhibits the reaction [LY 379268 inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased activity of CASP3 protein]]; WDR35 protein affects the reaction [Glucose results in increased activity of CASP3 protein]; Y 27632 inhibits the reaction [[Oxygen co-treated with [Oxygen deficiency co-treated with Glucose deficiency]] results in increased cleavage of CASP3 protein] Glucose results in increased expression of CASP3 mRNA; Glucose results in increased expression of CASP3 protein; Glucose results in increased expression of CASP3 protein modified form Glucose results in decreased expression of CASP3 mRNA |
CTD |
PMID:15322300 PMID:16135072 PMID:17065336 PMID:17293559 PMID:17309078 PMID:17928392 PMID:18004065 PMID:18088078 PMID:18791325 PMID:18973755 PMID:19767878 PMID:19892008 PMID:20028456 PMID:20224876 PMID:20370652 PMID:21803128 PMID:22524206 PMID:23192364 PMID:23453443 PMID:23637816 PMID:23758074 PMID:23770986 PMID:24349266 PMID:24451382 PMID:24682241 PMID:24720662 PMID:24810525 PMID:25238743 PMID:25305180 PMID:25488258 PMID:25516495 PMID:25896937 PMID:25997894 PMID:27234048 PMID:28106847 PMID:28675767 PMID:29095437 PMID:29457851 PMID:29702141 PMID:29719095 PMID:30076216 PMID:30144576 PMID:30431688 PMID:30802477 PMID:31115753 PMID:31655124 PMID:31935362 PMID:33508982 PMID:33759271 PMID:33764184 PMID:33962019 PMID:34212273 PMID:34801538 PMID:35191607 PMID:35264022 PMID:36462176 PMID:36928891 PMID:37417536 PMID:37619648 PMID:38069837 PMID:38115276 PMID:38124441 PMID:38444079 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
increases activity increases expression multiple interactions |
ISO EXP |
Glucose results in increased activity of CASP8 protein Glucose results in increased expression of CASP8 mRNA [Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CASP8 mRNA] [Glucose co-treated with Lycopene] results in increased expression of CASP8 mRNA; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8] |
CTD |
PMID:18791325 PMID:18973755 PMID:33962019 PMID:38444079 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage increases expression increases activity |
ISO EXP |
[Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; salvianolic acid inhibits the reaction [Glucose results in increased cleavage of CASP9 protein] Glucose results in increased expression of CASP9 mRNA; Glucose results in increased expression of CASP9 protein [Glucose co-treated with IGF2R protein modified form] results in increased expression of CASP9 protein; [Glucose co-treated with Lycopene] results in increased expression of CASP9 mRNA; [Glucose deficiency co-treated with Galactose co-treated with Pyruvic Acid] inhibits the reaction [Doxorubicin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP9]; Glucose results in increased expression of and results in increased cleavage of CASP9 protein; naringenin inhibits the reaction [Glucose results in increased expression of and results in increased cleavage of CASP9 protein]; naringenin inhibits the reaction [Glucose results in increased expression of CASP9 mRNA]; Scopoletin inhibits the reaction [Glucose results in increased expression of CASP9 protein] |
CTD |
PMID:17309078 PMID:18791325 PMID:23192364 PMID:25997894 PMID:30431688 PMID:36462176 PMID:37619648 PMID:38444079 More...
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Casz1 |
castor zinc finger 1 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CASZ1 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of CASZ1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400
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G |
Cat |
catalase |
multiple interactions decreases expression increases expression decreases activity increases activity |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein]]; [Glucose deficiency co-treated with CAT] affects the localization of ENDOG protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP3 protein; [Glucose deficiency co-treated with CAT] results in increased activity of CASP9 protein; [Glucose deficiency co-treated with CAT] results in increased cleavage of PARP1 protein; CAT inhibits the reaction [Glucose deficiency affects the folding of SOD2 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; CAT inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; CAT inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; cyclopamine inhibits the reaction [SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; Furans analog inhibits the reaction [Glucose results in decreased activity of CAT protein]; SHH protein inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CAT protein]; solanesol inhibits the reaction [Glucose results in decreased activity of CAT protein]; spiraeoside inhibits the reaction [Glucose results in increased activity of CAT protein] Glucose results in decreased expression of CAT mRNA 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]]; [Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein; CAT protein inhibits the reaction [Glucose results in increased expression of AGT mRNA]; CAT protein inhibits the reaction [Glucose results in increased expression of AGT protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Glucose results in increased expression of PLCB2 protein]; gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]; naringenin inhibits the reaction [Glucose results in decreased activity of CAT protein]; NFE2L2 protein affects the reaction [gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]]; Resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency co-treated with Oxygen] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Glucose results in decreased activity of CAT protein] Glucose deficiency results in increased expression of CAT protein; Glucose results in increased expression of CAT protein 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]]; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein; cyclopamine inhibits the reaction [polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]]; cyclopamine promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein]; gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]; NFE2L2 protein affects the reaction [gastrodin inhibits the reaction [Glucose results in decreased activity of CAT protein]]; polydatin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased activity of CAT protein] |
CTD |
PMID:12130563 PMID:17309078 PMID:20691780 PMID:21818840 PMID:23192364 PMID:23421680 PMID:23494737 PMID:26054749 PMID:27481074 PMID:28027979 PMID:28911973 PMID:32602595 PMID:33764184 PMID:37586544 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of CAV1 mRNA; Glucose results in decreased expression of CAV1 protein EGF protein inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]; Simvastatin inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA] |
CTD |
PMID:19816600 PMID:31655124 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucose results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Cbs |
cystathionine beta synthase |
increases expression decreases expression |
ISO EXP |
Glucose results in increased expression of CBS mRNA Glucose deficiency results in decreased expression of CBS mRNA |
CTD |
PMID:17178593 PMID:35577173 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Ccdc116 |
coiled-coil domain containing 116 |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CCDC116 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607
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G |
Ccdc169 |
coiled-coil domain containing 169 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CCDC169 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:139,321,644...139,351,161
Ensembl chr 2:139,321,670...139,351,161
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G |
Ccdc190 |
coiled-coil domain containing 190 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CCDC190 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:82,147,161...82,154,863
Ensembl chr13:82,147,176...82,154,863
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions increases secretion |
ISO EXP |
Glucose results in increased expression of CCL2 mRNA; Glucose results in increased expression of CCL2 protein (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCL2 protein]; [Glucose co-treated with fatostatin] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL2 mRNA; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; [Resveratrol affects the localization of RELA protein] inhibits the reaction [Glucose results in increased expression of CCL2 protein]; [Valsartan co-treated with Simvastatin] inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; aspalathin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Aspirin inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Bezafibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; CCL2 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; chromic chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; chromium nicotinic acid complex inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Clofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Clofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; diphenyleneiodonium inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Glucose inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]; HTS 466284 inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; isoangustone A inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; nothofagin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; nothofagin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; picolinic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; psicose inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; psicose inhibits the reaction [Glucose results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Quercetin inhibits the reaction [Glucose results in increased expression of MCP1 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Selenium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of CCL2 mRNA]] Glucose results in increased expression of CCL2 mRNA; Glucose results in increased expression of CCL2 protein; Glucose results in increased expression of MCP1 mRNA duanbanhuain A inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; duanbanhuain B inhibits the reaction [Glucose results in increased secretion of CCL2 protein] [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCL2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CCL2 mRNA; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; MIR27B mRNA affects the reaction [Glucose results in increased expression of CCL2 protein]; SNHG1 affects the reaction [Glucose results in increased expression of CCL2 mRNA]; SNHG1 affects the reaction [Glucose results in increased expression of CCL2 protein]; SNHG1 affects the reaction [MIR27B mRNA affects the reaction [Glucose results in increased expression of CCL2 protein]] |
CTD |
PMID:16143069 PMID:16600694 PMID:17178593 PMID:17607302 PMID:17655880 PMID:17665966 PMID:19132243 PMID:19158351 PMID:19225232 PMID:20542118 PMID:21367880 PMID:22036992 PMID:23329836 PMID:24436987 PMID:24513509 PMID:25338943 PMID:29420703 PMID:32613381 PMID:36243327 PMID:37567420 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl28 |
C-C motif chemokine ligand 28 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CCL28 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression multiple interactions decreases expression |
ISO |
Glucose results in increased expression of CCL5 mRNA [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of CCL5 mRNA Glucose results in decreased expression of CCL5 mRNA |
CTD |
PMID:17178593 PMID:31655124 PMID:32613381 PMID:32942007 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CCL7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn1 |
cellular communication network factor 1 |
increases expression |
ISO |
Glucose results in increased expression of CCN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; Cadmium inhibits the reaction [Glucose results in increased expression of CCN2 protein]; CCL2 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; CCN2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency]; fatostatin inhibits the reaction [Glucose results in increased expression of CCN2 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of CCN2 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of CCN2 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CCN2 protein]] Glucose results in increased expression of CCN2 mRNA; Glucose results in increased expression of CCN2 protein |
CTD |
PMID:10026205 PMID:14586741 PMID:19369054 PMID:21124846 PMID:21367880 PMID:22031849 PMID:26891083 PMID:33270355 More...
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCNB1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnd1 |
cyclin D1 |
increases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of CCND1; Glucose results in increased expression of CCND1 mRNA [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA] resveratrol inhibits the reaction [Glucose results in increased expression of CCND1 protein] [Glucose co-treated with resveratrol] results in decreased expression of CCND1 mRNA; resveratrol inhibits the reaction [Glucose results in increased expression of CCND1 mRNA] |
CTD |
PMID:23690508 PMID:24064760 PMID:24971582 PMID:27049278 PMID:27481074 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
multiple interactions |
ISO |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND2 mRNA] |
CTD |
PMID:27481074 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccne1 |
cyclin E1 |
increases expression multiple interactions |
EXP |
Glucose results in increased expression of CCNE1 protein resveratrol inhibits the reaction [Glucose results in increased expression of CCNE1 protein] |
CTD |
PMID:24971582 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccnl1 |
cyclin L1 |
increases expression |
ISO |
Glucose results in increased expression of CCNL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368
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G |
Ccr10 |
C-C motif chemokine receptor 10 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CCR10 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
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G |
Ccr6 |
C-C motif chemokine receptor 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CCR6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
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G |
Ccr7 |
C-C motif chemokine receptor 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CCR7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309
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G |
Ccs |
copper chaperone for superoxide dismutase |
multiple interactions |
EXP |
[Glucose co-treated with Lycopene] results in increased expression of CCS mRNA |
CTD |
PMID:38444079 |
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NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
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G |
Cd14 |
CD14 molecule |
multiple interactions |
ISO |
CD14 protein affects the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased secretion of MMP1 protein]]; Curcumin inhibits the reaction [Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein]]; Glucose promotes the reaction [Lipopolysaccharides results in increased expression of CD14 protein] |
CTD |
PMID:18180316 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd151 |
CD151 molecule (Raph blood group) |
multiple interactions |
EXP |
CD151 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 1:196,564,744...196,568,753
Ensembl chr 1:196,565,181...196,568,753
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G |
Cd160 |
CD160 molecule |
decreases expression |
ISO |
Glucose results in decreased expression of CD160 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
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G |
Cd163 |
CD163 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD163 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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G |
Cd19 |
CD19 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CD19 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:180,987,286...180,993,920
Ensembl chr 1:180,987,286...180,993,975
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G |
Cd1d1 |
CD1d1 molecule |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CD1D1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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G |
Cd226 |
CD226 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD226 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
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G |
Cd247 |
Cd247 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD247 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
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G |
Cd300a |
Cd300a molecule |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CD300A mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD300A mRNA |
CTD |
PMID:31525975 PMID:37567420 |
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NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
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G |
Cd300lb |
CD300 molecule-like family member b |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD300LB mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:99,964,801...99,974,790
Ensembl chr10:99,964,801...99,974,790
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO |
(R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; lanifibranor inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Rosiglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; saroglitazar inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA] Glucose results in increased expression of CD36 mRNA |
CTD |
PMID:32613381 PMID:36156098 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD3E mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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G |
Cd40lg |
CD40 ligand |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD40LG mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CD44 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CD44 mRNA |
CTD |
PMID:17178593 PMID:37567420 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd48 |
Cd48 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD48 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142
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G |
Cd5 |
Cd5 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CD5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
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G |
Cd52 |
CD52 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD52 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:146,319,789...146,321,348
Ensembl chr 5:146,319,969...146,321,348
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G |
Cd6 |
Cd6 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634
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G |
Cd74 |
CD74 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CD74 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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G |
Cd8b |
CD8 subunit beta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD8B1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553
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G |
Cd96 |
CD96 molecule |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CD96 mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:54,702,290...54,776,618
Ensembl chr11:54,702,290...54,776,621
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G |
Cdc42 |
cell division cycle 42 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CDC42 mRNA; Glucose results in increased expression of CDC42 protein Eucalyptol inhibits the reaction [Glucose results in increased expression of CDC42 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDC42 mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDC42 protein] |
CTD |
PMID:24659233 PMID:31483951 |
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NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO |
4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; [Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [[Glucose co-treated with TGFB1 protein] results in decreased expression of CDH1 protein]; MAPK14 protein promotes the reaction [Glucose results in decreased expression of CDH1 protein] Glucose results in decreased expression of CDH1 mRNA; Glucose results in decreased expression of CDH1 protein |
CTD |
PMID:21829520 PMID:26045780 PMID:29163160 PMID:33992720 PMID:35445903 PMID:35961541 More...
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh5 |
cadherin 5 |
decreases expression |
ISO |
Glucose results in decreased expression of CDH5 mRNA |
CTD |
PMID:31655124 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CDK1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CDK1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk9 |
cyclin-dependent kinase 9 |
increases phosphorylation multiple interactions |
ISO |
Glucose results in increased phosphorylation of CDK9 protein 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Glucose results in increased phosphorylation of CDK9 protein]; CDK9 protein affects the reaction [Glucose results in increased expression of COL4A4 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of IL1B mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of IL6 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of NOS2 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of TGFB1 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of TNF mRNA]; CDK9 protein affects the reaction [Glucose results in increased phosphorylation of MAPK1 protein]; CDK9 protein affects the reaction [Glucose results in increased phosphorylation of MAPK3 protein]; CDK9 protein affects the reaction [Glucose results in increased secretion of IL6 protein]; CDK9 protein affects the reaction [Glucose results in increased secretion of TNF protein] |
CTD |
PMID:33631230 |
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NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression decreases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of CDKN1A mRNA Glucose results in decreased expression of CDKN1A protein Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]; NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; TGFB1 protein promotes the reaction [Glucose promotes the reaction [SETD7 protein binds to CDKN1A promoter]]; TGFB1 protein promotes the reaction [Glucose results in increased expression of CDKN1A mRNA] Glucose results in increased expression of CDKN1A mRNA; Glucose results in increased expression of CDKN1A protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of CDKN1A mRNA]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of CDKN1A protein]]; [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA; [Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA; CDKN1A protein affects the reaction [Glucose results in increased expression of GLB1 protein]; Fluorometholone inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1A mRNA]; Melatonin inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Phytic Acid inhibits the reaction [Glucose results in increased expression of CDKN1A mRNA]; Phytic Acid inhibits the reaction [Glucose results in increased expression of CDKN1A protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1A mRNA]; SIRT1 protein mutant form inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased expression of CDKN1A mRNA]; TAS1R1 protein affects the reaction [Glucose results in decreased expression of CDKN1A protein] |
CTD |
PMID:17178593 PMID:22561310 PMID:24451382 PMID:27049278 PMID:27652271 PMID:33962019 PMID:33992720 PMID:35264022 PMID:38000455 PMID:38483099 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression multiple interactions |
EXP ISO |
Glucose results in increased expression of CDKN1B protein [Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CDKN1B mRNA] NAD inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; Resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; SIRT1 protein promotes the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CDKN1B protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of CDKN1B protein]] |
CTD |
PMID:22561310 PMID:33962019 PMID:33992720 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of CDKN2A protein; Glucose results in increased expression of CDKN2A protein alternative form CDKN2A protein affects the reaction [Glucose results in increased expression of GLB1 protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of CDKN2A protein alternative form] |
CTD |
PMID:23494737 PMID:38483099 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Ceacam1 |
CEA cell adhesion molecule 1 |
multiple interactions decreases expression decreases secretion |
ISO |
cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased expression of CEACAM1 mRNA]; cobaltiprotoporphyrin inhibits the reaction [Glucose results in decreased secretion of CEACAM1 protein] |
CTD |
PMID:19924377 |
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NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
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G |
Ceacam19 |
CEA cell adhesion molecule 19 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CEACAM19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:79,542,107...79,550,927
Ensembl chr 1:79,542,107...79,550,927
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
CEBPA protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPA protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPA protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPA protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPA protein] |
CTD |
PMID:24376792 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
CEBPB protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPB protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPB protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPB protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPB protein] CEBPB protein inhibits the reaction [Glucose results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of and results in decreased activity of MMP2 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of COL3A1 protein]; CEBPB protein inhibits the reaction [Glucose results in increased expression of TGFB1 protein]; Glucose inhibits the reaction [CEBPB protein binds to ACE2 promoter] Glucose results in decreased expression of CEBPB protein |
CTD |
PMID:24376792 PMID:28482072 PMID:29266779 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions |
ISO |
CEBPD protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPD protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; Glucose promotes the reaction [CEBPD protein binds to EDN1 promoter]; Glucose results in increased localization of and results in increased activity of CEBPD protein; pyrazolanthrone inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein]; SB 203580 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein]; U 0126 inhibits the reaction [Glucose results in increased localization of and results in increased activity of CEBPD protein] |
CTD |
PMID:24376792 |
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NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Celf3 |
CUGBP, Elav-like family member 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of CELF3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:182,116,034...182,130,163
Ensembl chr 2:182,116,073...182,130,163
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G |
Celf4 |
CUGBP, Elav-like family member 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELF4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786
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G |
Celsr1 |
cadherin, EGF LAG seven-pass G-type receptor 1 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CELSR1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164
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G |
Celsr3 |
cadherin, EGF LAG seven-pass G-type receptor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CELSR3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CELSR3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354
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G |
Cemip |
cell migration inducing hyaluronidase 1 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CEMIP mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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G |
Cenpf |
centromere protein F |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CENPF mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Cert1 |
ceramide transporter 1 |
multiple interactions increases expression |
EXP |
rhodioloside inhibits the reaction [Glucose results in increased expression of CERT1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of CERT1 mRNA] |
CTD |
PMID:29031534 |
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NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074
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G |
Ces2f |
carboxylesterase 2F |
increases expression |
ISO |
Glucose results in increased expression of CES2F mRNA |
CTD |
PMID:31525975 |
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NCBI chr19:7,527...14,898
Ensembl chr19:7,527...14,898
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G |
Ces2h |
carboxylesterase 2H |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CES2H mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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G |
Cfap45 |
cilia and flagella associated protein 45 |
increases expression |
ISO |
Glucose results in increased expression of CFAP45 mRNA |
CTD |
PMID:31525975 |
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NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878
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G |
Cfap74 |
cilia and flagella associated protein 74 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CFAP74 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:165,970,611...166,046,068
Ensembl chr 5:165,979,805...166,046,071
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G |
Cfap97d1 |
CFAP97 domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CFAP97D1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:86,933,585...86,944,566
Ensembl chr10:86,933,808...86,938,244
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G |
Cfd |
complement factor D |
decreases expression multiple interactions |
EXP ISO |
Glucose results in decreased expression of CFD mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CFD mRNA |
CTD |
PMID:3299706 PMID:37567420 |
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NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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G |
Cfl1 |
cofilin 1 |
increases secretion |
ISO |
Glucose deficiency results in increased secretion of CFL1 protein |
CTD |
PMID:24802182 |
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NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Cfp |
complement factor properdin |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of CFP mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of CFP mRNA] |
CTD |
PMID:33448797 |
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NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573
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G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
multiple interactions |
EXP |
CHAC1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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G |
Chd2 |
chromodomain helicase DNA binding protein 2 |
multiple interactions |
ISO |
Glucose promotes the reaction [TCF19 protein binds to CHD2 protein] |
CTD |
PMID:29042441 |
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NCBI chr 1:127,188,146...127,317,041
Ensembl chr 1:127,190,059...127,300,502
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G |
Chgb |
chromogranin B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHGB mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
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G |
Chkb |
choline kinase beta |
multiple interactions |
EXP |
CHKB protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 7:120,500,960...120,504,359
Ensembl chr 7:120,500,984...120,504,461
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G |
Chrdl2 |
chordin-like 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CHRDL2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CHRDL2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:154,343,201...154,370,651
Ensembl chr 1:154,343,201...154,370,640
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
increases expression |
EXP |
Glucose results in increased expression of CHRM2 mRNA |
CTD |
PMID:18715473 |
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NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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G |
Chrna2 |
cholinergic receptor nicotinic alpha 2 subunit |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CHRNA2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
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G |
Cimap1c |
ciliary microtubule associated protein 1C |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CIMAP1C mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:57,248,746...57,281,084
Ensembl chr 8:57,248,746...57,281,004
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G |
Ckap2 |
cytoskeleton associated protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CKAP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Ckb |
creatine kinase B |
multiple interactions increases activity |
ISO |
Glucose inhibits the reaction [daidzein results in increased activity of CKB protein]; Glucose inhibits the reaction [Dihydrotestosterone results in increased activity of CKB protein]; Glucose inhibits the reaction [Estradiol results in increased activity of CKB protein]; Glucose inhibits the reaction [Genistein results in increased activity of CKB protein] Glucose results in increased activity of CKB protein |
CTD |
PMID:16621514 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
increases expression |
ISO |
Glucose results in increased expression of CKS2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:13,570,611...13,575,770
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G |
Clec4a |
C-type lectin domain family 4, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLEC4N mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:156,340,439...156,434,212
Ensembl chr 4:156,414,688...156,432,402
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G |
Clec4e |
C-type lectin domain family 4, member E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLEC4E mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
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G |
Clhc1 |
clathrin heavy chain linker domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CLHC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:103,288,116...103,328,725
Ensembl chr14:103,288,134...103,328,715
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G |
Clic6 |
chloride intracellular channel 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLIC6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:31,737,813...31,780,360
Ensembl chr11:31,737,813...31,780,061
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G |
Clspn |
claspin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CLSPN mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
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G |
Clstn3 |
calsyntenin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CLSTN3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
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G |
Cma1 |
chymase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CMA1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
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G |
Cnih2 |
cornichon family AMPA receptor auxiliary protein 2 |
increases expression |
ISO |
Glucose results in increased expression of CNIH2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089
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G |
Cnn1 |
calponin 1 |
increases methylation decreases expression multiple interactions |
ISO |
Glucose results in increased methylation of CNN1 gene Glucose results in decreased expression of CNN1 mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of CNN1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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G |
Cnr1 |
cannabinoid receptor 1 |
decreases expression multiple interactions increases expression |
EXP |
Glucose results in decreased expression of CNR1 mRNA MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Glucose results in increased expression of CNR1 protein] Glucose results in increased expression of CNR1 mRNA; Glucose results in increased expression of CNR1 protein |
CTD |
PMID:19501110 PMID:30642005 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cntn4 |
contactin 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CNTN4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:138,624,584...139,622,499
Ensembl chr 4:139,099,152...139,621,090
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G |
Cntnap2 |
contactin associated protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CNTNAP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027
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G |
Cntnap5b |
contactin associated protein family member 5B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CNTNAP5A mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:17,863,367...18,766,983
Ensembl chr13:18,093,420...18,761,014
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G |
Col19a1 |
collagen type XIX alpha 1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL19A1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:26,673,916...27,022,139
Ensembl chr 9:26,675,391...27,022,106
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G |
Col1a1 |
collagen type I alpha 1 chain |
affects secretion decreases expression increases expression multiple interactions |
ISO EXP |
Glucose deficiency affects the secretion of COL1A1 protein Glucose results in decreased expression of COL1A1 mRNA Glucose results in increased expression of COL1A1 mRNA; Glucose results in increased expression of COL1A1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in decreased expression of COL1A1 mRNA]]; DKK1 protein inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Melatonin inhibits the reaction [Glucose results in decreased expression of COL1A1 mRNA]; MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL1A1 protein]]; MIR142 inhibits the reaction [Glucose results in increased expression of COL1A1 protein]; Phytic Acid inhibits the reaction [Glucose results in decreased expression of COL1A1 mRNA]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in increased expression of COL1A1 protein]]; TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL1A1 protein] Curcumin analog inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA] |
CTD |
PMID:24802182 PMID:28700904 PMID:29163160 PMID:38000455 PMID:38124441 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions increases secretion increases expression |
ISO |
troglitazone inhibits the reaction [Glucose results in increased expression of COL1A2 mRNA] Glucose deficiency results in increased secretion of COL1A2 protein |
CTD |
PMID:17199790 PMID:24802182 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col27a1 |
collagen type XXVII alpha 1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of COL27A1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174
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G |
Col3a1 |
collagen type III alpha 1 chain |
affects secretion increases expression multiple interactions |
ISO |
Glucose deficiency affects the secretion of COL3A1 protein Glucose results in increased expression of COL3A1 protein CEBPB protein inhibits the reaction [Glucose results in increased expression of COL3A1 protein]; Valsartan inhibits the reaction [Glucose results in increased expression of COL3A1 protein] |
CTD |
PMID:24802182 PMID:29266779 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a1 |
collagen type IV alpha 1 chain |
multiple interactions increases expression |
EXP ISO |
[eplerenone co-treated with Enalapril] inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin analog inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]; Enalapril inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]]; eplerenone inhibits the reaction [Aldosterone promotes the reaction [Glucose results in increased expression of COL4A1 mRNA]] MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL4A1 protein]]; MIR142 inhibits the reaction [Glucose results in increased expression of COL4A1 protein]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in increased expression of COL4A1 protein]]; TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of COL4A1 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA]]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of COL4A1 mRNA] |
CTD |
PMID:18682491 PMID:28700904 PMID:33270355 PMID:38124441 |
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NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Col4a2 |
collagen type IV alpha 2 chain |
affects secretion |
ISO |
Glucose deficiency affects the secretion of COL4A2 protein |
CTD |
PMID:24802182 |
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NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
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G |
Col4a4 |
collagen type IV alpha 4 chain |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of COL4A4 mRNA 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Glucose results in increased expression of COL4A4 mRNA]; CDK9 protein affects the reaction [Glucose results in increased expression of COL4A4 mRNA] |
CTD |
PMID:33631230 |
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NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
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G |
Col5a1 |
collagen type V alpha 1 chain |
affects secretion |
ISO |
Glucose deficiency affects the secretion of COL5A1 protein |
CTD |
PMID:24802182 |
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NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Col5a2 |
collagen type V alpha 2 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL5A2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154
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G |
Col6a1 |
collagen type VI alpha 1 chain |
affects secretion |
ISO |
Glucose deficiency affects the secretion of COL6A1 protein |
CTD |
PMID:24802182 |
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NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Col6a2 |
collagen type VI alpha 2 chain |
affects secretion |
ISO |
Glucose deficiency affects the secretion of COL6A2 protein |
CTD |
PMID:24802182 |
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NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
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G |
Col6a5 |
collagen type VI alpha 5 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A5 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL6A5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:106,483,806...106,584,114
Ensembl chr 8:106,483,799...106,584,113
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G |
Col6a6 |
collagen type VI alpha 6 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of COL6A6 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of COL6A6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:106,318,010...106,473,419
Ensembl chr 8:106,306,422...106,473,472
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G |
Col7a1 |
collagen type VII alpha 1 chain |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of COL7A1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
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G |
Col8a2 |
collagen type VIII alpha 2 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of COL8A2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850
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G |
Commd9 |
COMM domain containing 9 |
multiple interactions |
EXP |
COMMD9 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439
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G |
Cox4i1 |
cytochrome c oxidase subunit 4i1 |
increases expression multiple interactions |
ISO |
Glucose deficiency results in increased expression of COX4I1 mRNA [Glucose co-treated with Palmitic Acid] results in decreased expression of COX4I1 mRNA |
CTD |
PMID:26811028 PMID:39265716 |
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NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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G |
Cox5b |
cytochrome c oxidase subunit 5B |
multiple interactions |
EXP |
COX5B protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
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G |
Cox6a2 |
cytochrome c oxidase subunit 6A2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of COX6A2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
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G |
Cpe |
carboxypeptidase E |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CPE mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233
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G |
Cpq |
carboxypeptidase Q |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CPQ mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of CPT1A protein (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA; Bezafibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Ditiocarb inhibits the reaction [YY1 protein inhibits the reaction [jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of CPT1A protein]]]]; Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of CPT1A protein]; Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of CPT1A protein]]; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; YY1 protein inhibits the reaction [jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in decreased expression of CPT1A protein]]] Glucose results in decreased expression of CPT1A mRNA; Glucose results in decreased expression of CPT1A protein |
CTD |
PMID:23090186 PMID:32613381 PMID:36156098 PMID:39059604 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
affects expression multiple interactions |
EXP ISO |
Glucose affects the expression of CPT2 mRNA [Glucose co-treated with Palmitic Acid] results in decreased expression of CPT2 mRNA |
CTD |
PMID:24349266 PMID:39265716 |
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NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases activity multiple interactions |
ISO EXP |
Glucose results in increased activity of CREB1 protein [Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased phosphorylation of CREB1 protein; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Oxygen co-treated with Glucose deficiency co-treated with 2-(4-methoxyphenyl)ethyl-2-acetamido-2-deoxyglucopyranoside] results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:15767253 PMID:24726522 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CREB3L3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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G |
Crlf1 |
cytokine receptor-like factor 1 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
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G |
Crmp1 |
collapsin response mediator protein 1 |
multiple interactions |
EXP |
CRMP1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177
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G |
Crtac1 |
cartilage acidic protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CRTAC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
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G |
Cryaa |
crystallin, alpha A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CRYAA mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CRYAA mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:9,783,605...9,787,351
Ensembl chr20:9,783,605...9,787,349
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G |
Crybg2 |
crystallin beta-gamma domain containing 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CRYBG2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:146,286,406...146,318,417
Ensembl chr 5:146,286,925...146,323,666
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G |
Cs |
citrate synthase |
increases activity multiple interactions |
ISO |
Glucose results in increased activity of CS protein Desipramine inhibits the reaction [Glucose results in increased activity of CS protein] |
CTD |
PMID:32481596 |
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NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421
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G |
Csrnp1 |
cysteine and serine rich nuclear protein 1 |
increases expression |
ISO |
Glucose results in increased expression of CSRNP1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
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G |
Cst6 |
cystatin E/M |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of CST6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
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G |
Cth |
cystathionine gamma-lyase |
decreases expression |
EXP |
Glucose deficiency results in decreased expression of CTH mRNA; Glucose deficiency results in decreased expression of CTH protein |
CTD |
PMID:35577173 |
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NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctnnb1 |
catenin beta 1 |
decreases expression affects localization multiple interactions increases expression |
EXP ISO |
Glucose results in decreased expression of CTNNB1 mRNA; Glucose results in decreased expression of CTNNB1 protein Glucose affects the localization of CTNNB1 protein [Glucose co-treated with ICG 001] results in decreased expression of CTNNB1 protein; [ICG 001 co-treated with Glucose] affects the localization of CTNNB1 protein; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 protein]; Panax notoginseng extract inhibits the reaction [[Glucose co-treated with ICG 001] results in decreased expression of CTNNB1 protein]; Panax notoginseng extract inhibits the reaction [[ICG 001 co-treated with Glucose] affects the localization of CTNNB1 protein]; Panax notoginseng extract inhibits the reaction [Glucose affects the localization of CTNNB1 protein]; Panax notoginseng extract inhibits the reaction [Glucose results in decreased expression of CTNNB1 protein] Glucose results in increased expression of CTNNB1 mRNA; Glucose results in increased expression of CTNNB1 protein Simvastatin inhibits the reaction [Glucose results in decreased expression of CTNNB1 protein] |
CTD |
PMID:18004065 PMID:21818840 PMID:29163160 PMID:35385194 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
multiple interactions increases expression |
ISO |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein; Melatonin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CTSB protein] Glucose results in increased expression of CTSB mRNA |
CTD |
PMID:17178593 PMID:21392095 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsl |
cathepsin L |
increases secretion |
ISO |
Glucose deficiency results in increased secretion of CTSL protein |
CTD |
PMID:24802182 |
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NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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G |
Ctsw |
cathepsin W |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CTSW mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:202,772,395...202,777,021
Ensembl chr 1:202,772,572...202,775,964
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G |
Cttn |
cortactin |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of CTTN protein Eucalyptol inhibits the reaction [Glucose results in decreased expression of CTTN protein] |
CTD |
PMID:31483951 |
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NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Clofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] Glucose results in increased expression of CX3CL1 mRNA; Glucose results in increased expression of CX3CL1 protein |
CTD |
PMID:19132243 PMID:31655124 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CXCL10 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL10 mRNA |
CTD |
PMID:17178593 PMID:37567420 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
Glucose results in increased expression of CXCL2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of CXCL1 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CXCL1 mRNA |
CTD |
PMID:17178593 PMID:37567420 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of CXCL9 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
multiple interactions |
ISO |
[Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCR4 mRNA; [Glucose co-treated with Oxygen deficiency] results in decreased expression of CXCR4 protein |
CTD |
PMID:18227068 |
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NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyba |
cytochrome b-245 alpha chain |
increases expression decreases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of CYBA protein Glucose results in decreased expression of CYBA mRNA Glucose results in increased expression of CYBA mRNA; Glucose results in increased expression of CYBA protein [[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species; CYBA protein promotes the reaction [Glucose results in increased chemical synthesis of Reactive Oxygen Species]; CYBA protein promotes the reaction [Glucose results in increased expression of FN1 protein]; farrerol inhibits the reaction [Glucose results in increased expression of CYBA mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of CYBA protein]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of CYBA protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBA mRNA]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBA protein] dorsomorphin inhibits the reaction [Rosiglitazone inhibits the reaction [Glucose results in increased expression of CYBA protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in increased expression of CYBA protein]; Rosiglitazone inhibits the reaction [Glucose results in increased expression of CYBA protein] |
CTD |
PMID:17916771 PMID:18088078 PMID:22245600 PMID:31838053 PMID:32942007 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions increases expression increases localization |
ISO EXP |
acetovanillone inhibits the reaction [Glucose results in increased expression of and results in increased activity of CYBB protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of CYBB protein]; Glucose results in increased expression of and results in increased activity of CYBB protein; Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB mRNA]; Telmisartan inhibits the reaction [Glucose results in increased expression of CYBB protein] Glucose results in increased expression of CYBB mRNA; Glucose results in increased expression of CYBB protein dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of CYBB protein]]; Resveratrol inhibits the reaction [Glucose results in increased expression of CYBB protein] Glucose results in increased localization of CYBB protein [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein; Prodigiosin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein]; prolinedithiocarbamate inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CYBB protein] |
CTD |
PMID:19878672 PMID:21925195 PMID:22253932 PMID:26054749 PMID:31494106 PMID:31838053 PMID:34464088 More...
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
affects localization multiple interactions increases expression |
EXP ISO |
Glucose affects the localization of CYCS protein naringenin inhibits the reaction [Glucose affects the localization of CYCS protein]; Scopoletin inhibits the reaction [Glucose results in increased expression of CYCS protein] Glucose results in increased expression of CYCS mRNA; Glucose results in increased expression of CYCS protein [Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA; diallyl trisulfide inhibits the reaction [Glucose results in increased expression of CYCS protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of CYCS mRNA]; MitoTEMPO inhibits the reaction [Glucose results in increased expression of CYCS protein] |
CTD |
PMID:23192364 PMID:31115753 PMID:33962019 PMID:37619648 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cygb |
cytoglobin |
decreases expression |
ISO |
Glucose results in decreased expression of CYGB mRNA |
CTD |
PMID:32942007 |
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NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
EXP |
Glucose results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:15017115 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO |
Polyphenols promotes the reaction [Glucose results in increased expression of CYP1A1 mRNA] CYP1A1 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:21682256 PMID:31776611 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
CYP1A2 protein affects the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:31776611 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Oxygen co-treated with Glucose] inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein]; [Oxygen deficiency co-treated with Glucose deficiency] results in decreased expression of CYP1B1 protein |
CTD |
PMID:28400208 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CYP27B1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CYP2B10 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] Glucose results in increased expression of CYP2E1 protein Fatty Acids, Nonesterified promotes the reaction [Glucose results in increased expression of CYP2E1 protein]; jujuboside A inhibits the reaction [Fatty Acids, Nonesterified promotes the reaction [Glucose results in increased expression of CYP2E1 protein]] |
CTD |
PMID:33448797 PMID:39059604 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of CYP3A13 mRNA |
CTD |
PMID:37567420 |
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NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of CYP7B1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cysrt1 |
cysteine rich tail 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of CYSRT1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:8,054,195...8,057,846
Ensembl chr 3:8,053,482...8,059,721
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G |
Daxx |
death-domain associated protein |
multiple interactions affects localization |
ISO |
Glucose deficiency promotes the reaction [DAXX protein binds to MAP3K5 protein] Glucose deficiency affects the localization of DAXX protein |
CTD |
PMID:14505347 |
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NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucose results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Dbn1 |
drebrin 1 |
decreases expression multiple interactions |
EXP |
Glucose results in decreased expression of DBN1 mRNA; Glucose results in decreased expression of DBN1 protein Curcumin inhibits the reaction [Glucose results in decreased expression of DBN1 mRNA] |
CTD |
PMID:23333261 |
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NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DBP mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DBP mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
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G |
Dclk1 |
doublecortin-like kinase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DCLK1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956
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G |
Dcx |
doublecortin |
increases expression |
ISO |
Glucose results in increased expression of DCX protein |
CTD |
PMID:23776576 |
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NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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G |
Ddias |
DNA damage-induced apoptosis suppressor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DDIAS mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
decreases expression multiple interactions increases expression |
ISO EXP |
Glucose results in decreased expression of DDIT3 mRNA Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; Metformin inhibits the reaction [Glucose results in increased expression of DDIT3 protein] [Galactose co-treated with Glucose deficiency] promotes the reaction [leflunomide results in increased expression of DDIT3 protein] 2-aminoethoxydiphenyl borate inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; DDIT3 affects the reaction [Glucose results in decreased expression of PPARGC1A mRNA]; Gadolinium inhibits the reaction [Glucose results in increased expression of DDIT3 protein]; Glucose inhibits the reaction [DDIT3 protein binds to PPARGC1A promoter]; TRPM7 protein affects the reaction [Glucose results in increased expression of DDIT3 protein]; waixenicin A inhibits the reaction [Glucose results in increased expression of DDIT3 protein] Glucose deficiency results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 mRNA; Glucose results in increased expression of DDIT3 protein Glucose deficiency results in increased expression of DDIT3 protein; Glucose results in increased expression of DDIT3 protein |
CTD |
PMID:17178593 PMID:21337367 PMID:24349266 PMID:27226639 PMID:28482072 PMID:29427785 PMID:30076216 PMID:34801538 More...
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddx3x |
DEAD-box helicase 3, X-linked |
increases degradation |
ISO |
Glucose deficiency results in increased degradation of DDX3X protein |
CTD |
PMID:30821613 |
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NCBI chr X:9,479,532...9,493,169
Ensembl chr X:9,479,532...9,493,168
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G |
Defb24 |
defensin beta 24 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DEFB19 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:141,046,571...141,052,706
Ensembl chr 3:141,046,564...141,052,753
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G |
Dek |
DEK proto-oncogene |
multiple interactions |
ISO |
DEK protein affects the chemical synthesis of and affects the uptake of Glucose |
CTD |
PMID:28558019 |
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NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
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G |
Depp1 |
DEPP autophagy regulator 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DEPP1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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G |
Derl3 |
derlin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DERL3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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G |
Deup1 |
deuterosome assembly protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of DEUP1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DEUP1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199
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G |
Dgkd |
diacylglycerol kinase, delta |
multiple interactions affects localization |
ISO |
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [Glucose affects the localization of DGKD protein alternative form]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose affects the localization of DGKD protein alternative form] |
CTD |
PMID:22974639 |
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NCBI chr 9:88,516,686...88,607,349
Ensembl chr 9:88,516,715...88,607,345
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G |
Dhh |
desert hedgehog signaling molecule |
increases expression |
ISO |
Glucose results in increased expression of DHH mRNA |
CTD |
PMID:31525975 |
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NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
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G |
Dhps |
deoxyhypusine synthase |
multiple interactions |
EXP |
DHPS protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr19:23,082,454...23,086,544
Ensembl chr19:23,082,448...23,086,881
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G |
Dhrs9 |
dehydrogenase/reductase 9 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DHRS9 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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G |
Dhx58 |
DEXH-box helicase 58 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DHX58 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
multiple interactions increases expression |
ISO |
[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DIABLO mRNA] Glucose results in increased expression of DIABLO mRNA |
CTD |
PMID:33962019 |
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NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Diaph3 |
diaphanous-related formin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of DIAPH3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
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G |
Diras2 |
DIRAS family GTPase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DIRAS2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:12,730,040...12,761,511
Ensembl chr17:12,725,149...12,761,663
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G |
Disc1 |
DISC1 scaffold protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DISC1 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DISC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
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G |
Disp2 |
dispatched RND transporter family member 2 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of DISP2 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of DISP2 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:105,762,305...105,777,800
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
multiple interactions |
ISO |
DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in decreased expression of CDH1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of ACTA2 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of COL1A1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of CTNNB1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; DKK1 protein inhibits the reaction [Glucose results in increased expression of LEF1 mRNA] |
CTD |
PMID:29163160 |
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NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of DLK1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dmtn |
dematin actin binding protein |
increases methylation multiple interactions decreases expression |
ISO |
Glucose results in increased methylation of DMTN gene fucoxanthin inhibits the reaction [Glucose results in decreased expression of DMTN mRNA] |
CTD |
PMID:33448797 |
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NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
decreases expression |
ISO |
Glucose results in decreased expression of DNAJB11 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Glucose results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dnase1l3 |
deoxyribonuclease 1L3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of DNASE1L3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
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G |
Dnm1l |
dynamin 1-like |
increases expression multiple interactions |
EXP ISO |
Glucose results in increased expression of DNM1L protein [Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA; diallyl trisulfide inhibits the reaction [Glucose results in increased expression of DNM1L protein]; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of DNM1L mRNA] [Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of DNM1L protein; cinnamic acid inhibits the reaction [Glucose results in increased expression of DNM1L protein]; Metformin inhibits the reaction [Glucose results in increased expression of DNM1L protein]; qishen yiqi inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of DNM1L protein] |
CTD |
PMID:27684054 PMID:30144576 PMID:31115753 PMID:33962019 PMID:36806343 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
increases expression |
ISO |
Glucose results in increased expression of DNMT1 mRNA |
CTD |
PMID:29854080 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dok7 |
docking protein 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of DOK7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386
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G |
Dpep2 |
dipeptidase 2 |
increases expression |
ISO |
Glucose results in increased expression of DPEP2 mRNA |
CTD |
PMID:31525975 |
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NCBI chr19:33,883,557...33,896,487
Ensembl chr19:33,885,478...33,891,954
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G |
Dpp6 |
dipeptidyl peptidase like 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of DPP6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
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G |
Dscaml1 |
DS cell adhesion molecule-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of DSCAML1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:45,740,298...46,057,322
Ensembl chr 8:45,740,298...46,057,320
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G |
Duox1 |
dual oxidase 1 |
decreases expression |
ISO |
Glucose results in decreased expression of DUOX1 mRNA |
CTD |
PMID:32942007 |
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NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
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G |
Duox2 |
dual oxidase 2 |
decreases expression |
ISO |
Glucose results in decreased expression of DUOX2 mRNA |
CTD |
PMID:32942007 |
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NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902
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G |
Dusp1 |
dual specificity phosphatase 1 |
increases expression |
ISO |
Glucose results in increased expression of DUSP1 mRNA |
CTD |
PMID:17178593 PMID:32942007 |
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NCBI chr10:16,680,478...16,683,275
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Dusp13b |
dual specificity phosphatase 13B |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of DUSP13B mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of DUSP13B mRNA] |
CTD |
PMID:31525975 PMID:33448797 |
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NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Glucose results in increased expression of DUSP2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of DUSP5 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp6 |
dual specificity phosphatase 6 |
increases expression |
ISO |
Glucose results in increased expression of DUSP6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185
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G |
Ebln1 |
endogenous Bornavirus like nucleoprotein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of IGKV8-24 mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:78,938,645...78,940,651
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G |
Edaradd |
EDAR associated via death domain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EDARADD mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
decreases expression |
ISO |
Glucose results in decreased expression of EDEM1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Edn1 |
endothelin 1 |
multiple interactions increases expression decreases expression |
ISO EXP |
carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 protein]; CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; CEBPA protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPA protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; CEBPB protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPB protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; CEBPD protein affects the reaction [Glucose results in increased expression of and results in increased secretion of EDN1 protein]; CEBPD protein affects the reaction [Glucose results in increased expression of EDN1 mRNA]; diphenyleneiodonium inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Glucose promotes the reaction [CEBPA protein binds to EDN1 promoter]; Glucose promotes the reaction [CEBPB protein binds to EDN1 promoter]; Glucose promotes the reaction [CEBPD protein binds to EDN1 promoter]; Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]; pyrazolanthrone inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; SB 203580 inhibits the reaction [Glucose results in increased expression of EDN1 mRNA]; U 0126 inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; HIF1A protein affects the reaction [Glucose results in increased expression of EDN1 protein]; MIR217 mRNA affects the reaction [Glucose results in increased expression of EDN1 protein]; resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 protein]; SIRT1 protein affects the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of EDN1 protein]] Glucose results in increased expression of EDN1 mRNA; Glucose results in increased expression of EDN1 protein Glucose results in decreased expression of EDN1 mRNA |
CTD |
PMID:12821678 PMID:16428915 PMID:20691780 PMID:20960276 PMID:24376792 PMID:26891083 PMID:31655124 More...
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Edn3 |
endothelin 3 |
multiple interactions |
EXP |
EDN3 protein inhibits the reaction [SLC5A2 protein results in increased uptake of Glucose] |
CTD |
PMID:15127950 |
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NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
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G |
Ednra |
endothelin receptor type A |
increases expression |
ISO |
Glucose results in increased expression of EDNRA mRNA |
CTD |
PMID:31655124 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
multiple interactions |
EXP |
EEF1A1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
multiple interactions decreases phosphorylation |
ISO |
resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of EEF2 protein] |
CTD |
PMID:19765649 |
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NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
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G |
Eef2k |
eukaryotic elongation factor-2 kinase |
multiple interactions increases phosphorylation |
ISO |
resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EEF2K protein] |
CTD |
PMID:19765649 |
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NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
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G |
Efhc1 |
EF-hand domain containing 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of EFHC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:23,375,815...23,414,283
Ensembl chr 9:23,375,840...23,414,283
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
EGF protein inhibits the reaction [Glucose results in decreased expression of CAV1 mRNA]; EGF protein promotes the reaction [Glucose results in increased expression of TGFA mRNA]; Glucose promotes the reaction [EGF protein results in increased expression of TGFA mRNA] |
CTD |
PMID:8638660 PMID:19816600 |
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NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of EGFR protein; albiflorin inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of EGFR protein]; zhenwu decoction inhibits the reaction [[Palmitic Acid co-treated with Glucose] results in increased phosphorylation of EGFR protein] |
CTD |
PMID:37523837 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
ISO |
Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]; Valsartan inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased expression of EGR1 mRNA]] Glucose results in increased expression of EGR1 mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of EGR1 mRNA |
CTD |
PMID:17178593 PMID:19225232 PMID:37567420 |
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NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EGR2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Ehd3 |
EH-domain containing 3 |
multiple interactions |
EXP |
EHD3 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:21124846 |
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NCBI chr 6:21,640,861...21,665,601
Ensembl chr 6:21,639,290...21,665,236
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EHHADH mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions increases phosphorylation |
ISO |
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2AK2 protein]; Glucose promotes the reaction [EIF2AK2 protein results in increased activity of MAPK14 protein] |
CTD |
PMID:18973755 |
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NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2AK3 protein] Glucose results in increased phosphorylation of EIF2AK3 protein Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of EIF2AK3 protein]; Metformin inhibits the reaction [Glucose results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:31022492 PMID:34801538 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions increases phosphorylation |
ISO EXP |
acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein]; Metformin inhibits the reaction [Glucose results in increased phosphorylation of EIF2S1 protein] 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]; salubrinal inhibits the reaction [4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2S1 protein]] |
CTD |
PMID:18973755 PMID:31022492 PMID:34801538 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases degradation |
ISO |
Glucose deficiency results in increased degradation of EIF4A1 protein |
CTD |
PMID:30821613 |
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NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
increases phosphorylation multiple interactions |
ISO |
Glucose results in increased phosphorylation of EIF4E protein Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]; resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]]; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4E protein] |
CTD |
PMID:19765649 |
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NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
EXP ISO |
resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4EBP1 protein] [AKT1 protein mutant form results in increased susceptibility to Glucose deficiency] which results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:15806154 PMID:20332614 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
multiple interactions |
ISO |
Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]; resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]] |
CTD |
PMID:19765649 |
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NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
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G |
Eif4h |
eukaryotic translation initiation factor 4H |
increases degradation |
ISO |
Glucose deficiency results in increased degradation of EIF4H protein |
CTD |
PMID:30821613 |
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NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
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G |
Elapor1 |
endosome-lysosome associated apoptosis and autophagy regulator 1 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ELAPOR1 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of ELAPOR1 mRNA] |
CTD |
PMID:31525975 PMID:33448797 |
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NCBI chr 2:196,089,199...196,169,055
Ensembl chr 2:196,091,646...196,168,716
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G |
Elk3 |
ETS transcription factor ELK3 |
increases expression |
ISO |
Glucose results in increased expression of ELK3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of ELOVL6 mRNA (R)-2-(3-((benzoxazol-2-yl-d4 (3-(4-methoxyphenoxy-d7)propyl)amino)methyl)phenoxy) butanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; 2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxo-1-propenyl)phenoxyl)-2-methylpropanoic acid affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; [osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA; lanifibranor affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; Rosiglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA]; saroglitazar affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of ELOVL6 mRNA] |
CTD |
PMID:15066988 PMID:16790840 PMID:32613381 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Emc1 |
ER membrane protein complex subunit 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of EMC1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:151,608,557...151,633,888
Ensembl chr 5:151,608,568...151,633,888
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G |
Endog |
endonuclease G |
multiple interactions affects localization |
ISO EXP |
[Glucose deficiency co-treated with Acetylcysteine] affects the localization of ENDOG protein; [Glucose deficiency co-treated with CAT] affects the localization of ENDOG protein; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein Glucose affects the localization of ENDOG protein |
CTD |
PMID:17309078 PMID:23192364 |
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NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932
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G |
Enkur |
enkurin, TRPC channel interacting protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ENKUR mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:83,690,105...83,714,756
Ensembl chr17:83,690,797...83,714,408
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G |
Eno1 |
enolase 1 |
decreases secretion |
ISO |
Glucose deficiency results in decreased secretion of ENO1 protein |
CTD |
PMID:24802182 |
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NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
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G |
Eno2 |
enolase 2 |
increases secretion |
ISO |
Glucose deficiency results in increased secretion of ENO2 protein |
CTD |
PMID:24802182 |
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NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Entpd1 |
ectonucleoside triphosphate diphosphohydrolase 1 |
increases expression |
ISO |
Glucose results in increased expression of ENTPD1 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
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G |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ENTPD4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:44,630,878...44,658,654
Ensembl chr15:44,630,873...44,658,706
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions increases expression |
ISO |
[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; scutellarin inhibits the reaction [[cobaltous chloride co-treated with Glucose] promotes the reaction [HIF1A protein binds to EP300 protein]] |
CTD |
PMID:22228707 PMID:25192544 PMID:26045780 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epb42 |
erythrocyte membrane protein band 4.2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EPB42 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:107,979,709...107,997,932
Ensembl chr 3:107,979,713...107,997,932
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G |
Ephx4 |
epoxide hydrolase 4 |
decreases expression |
ISO |
Glucose results in decreased expression of EPHX4 mRNA |
CTD |
PMID:31525975 |
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NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
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G |
Epo |
erythropoietin |
multiple interactions |
ISO |
[EPO protein co-treated with Glucose] results in increased expression of RUNX2 mRNA; [EPO protein co-treated with Glucose] results in increased expression of RUNX2 protein; [EPO protein co-treated with Glucose] results in increased expression of SP7 mRNA; [EPO protein co-treated with Glucose] results in increased expression of SP7 protein |
CTD |
PMID:30894315 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Epop |
elongin BC and polycomb repressive complex 2 associated protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of EPOP mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912
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G |
Eppk1 |
epiplakin 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of EPPK1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:107,816,919...107,842,946
Ensembl chr 7:107,817,693...107,831,159
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G |
Epsti1 |
epithelial stromal interaction 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of EPSTI1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Quercetin] results in increased ubiquitination of ERBB2 protein; Glucose deficiency inhibits the reaction [Quercetin promotes the reaction [ERBB2 protein binds to HSP90AA1 protein]] |
CTD |
PMID:18655187 |
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NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
multiple interactions |
EXP |
[NRG1 protein binds to ERBB3 protein] which results in increased transport of Glucose |
CTD |
PMID:14711829 |
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NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
multiple interactions increases expression |
ISO |
3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC1 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC1 protein] Glucose results in increased expression of ERCC1 mRNA; Glucose results in increased expression of ERCC1 protein |
CTD |
PMID:22228707 |
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Ercc4 |
ERCC excision repair 4, endonuclease catalytic subunit |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ERCC4 mRNA; Glucose results in increased expression of ERCC4 protein 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of ERCC4 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of ERCC4 protein]; ERCC4 protein affects the reaction [Glucose results in increased expression of EP300 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of ERCC1 protein]; ERCC4 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of PARP1 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC4 mRNA]; trichostatin A inhibits the reaction [Glucose results in increased expression of ERCC4 protein] |
CTD |
PMID:22228707 |
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NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 Ensembl chr10:2,419,038...2,448,369
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
increases phosphorylation multiple interactions |
ISO EXP |
Glucose deficiency results in increased phosphorylation of ERN1 protein Glucose results in increased phosphorylation of ERN1 protein Chlorogenic Acid inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein]; Metformin inhibits the reaction [Glucose results in increased phosphorylation of ERN1 protein] 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of ERN1 protein]; [Glucose co-treated with TGFB1 protein] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Glucose co-treated with TGFB1 protein] results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:31022492 PMID:34801538 PMID:35961541 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of ERN2 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
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G |
Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
decreases expression increases expression multiple interactions |
ISO EXP |
Glucose results in decreased expression of ERO1A mRNA Glucose results in increased expression of ERO1A protein Chlorogenic Acid inhibits the reaction [Glucose results in increased expression of ERO1A protein]; Metformin inhibits the reaction [Glucose results in increased expression of ERO1A protein] |
CTD |
PMID:17178593 PMID:34801538 |
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NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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G |
Esr1 |
estrogen receptor 1 |
increases expression decreases expression multiple interactions increases phosphorylation increases abundance |
ISO EXP |
Glucose results in increased expression of ESR1 mRNA Glucose results in decreased expression of ESR1 mRNA [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA; ESR1 protein promotes the reaction [[Resveratrol results in increased localization of SLC2A4 protein] which results in increased uptake of Glucose]; tetrahydropalmatine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of ESR1 mRNA] Glucose results in increased phosphorylation of ESR1 protein ESR1 protein results in increased abundance of Glucose Endosulfan promotes the reaction [ESR1 protein results in increased abundance of Glucose] |
CTD |
PMID:16621514 PMID:18426865 PMID:23690508 PMID:31520823 PMID:37606869 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
increases expression decreases expression |
ISO |
Glucose results in increased expression of ESR2 mRNA Glucose results in decreased expression of ESR2 mRNA |
CTD |
PMID:16621514 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Esrp1 |
epithelial splicing regulatory protein 1 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of ESRP1 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of ESRP1 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062
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G |
Esrra |
estrogen related receptor, alpha |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of ESRRA protein resveratrol inhibits the reaction [Glucose results in decreased expression of ESRRA protein] |
CTD |
PMID:23090186 |
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NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
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G |
Ezr |
ezrin |
multiple interactions decreases expression |
ISO |
Eucalyptol inhibits the reaction [Glucose results in decreased expression of EZR protein] |
CTD |
PMID:31483951 |
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NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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G |
F13a1 |
coagulation factor XIII A1 chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of F13A1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700
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G |
F2r |
coagulation factor II (thrombin) receptor |
decreases expression |
ISO |
Glucose results in decreased expression of F2R mRNA |
CTD |
PMID:31655124 |
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NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases expression |
ISO |
Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 mRNA]; Fluorometholone inhibits the reaction [Glucose results in increased expression of F3 protein] Glucose results in increased expression of F3 mRNA; Glucose results in increased expression of F3 protein |
CTD |
PMID:35264022 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
F7 |
coagulation factor VII |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of F7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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G |
Fabp1 |
fatty acid binding protein 1 |
increases expression |
ISO |
Glucose results in increased expression of FABP1 mRNA |
CTD |
PMID:36156098 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions increases expression |
ISO EXP |
[Glucose deficiency co-treated with ALB protein] results in decreased expression of FABP4 mRNA; [Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Clofibrate] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA [Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; dioxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; oxybenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA] Glucose results in increased expression of FABP4 mRNA |
CTD |
PMID:3299706 PMID:8536680 PMID:32407875 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fam163a |
family with sequence similarity 163, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FAM163A mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:68,262,867...68,341,323
Ensembl chr13:68,262,872...68,341,049
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G |
Fam163b |
family with sequence similarity 163, member B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAM163B mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 3:10,437,383...10,466,458
Ensembl chr 3:10,437,383...10,466,458
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G |
Fam167a |
family with sequence similarity 167, member A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAM167A mRNA |
CTD |
PMID:37567420 |
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NCBI chr15:37,685,221...37,715,472
Ensembl chr15:37,700,919...37,715,469
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G |
Fam178b |
family with sequence similarity 178, member B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FAM178B mRNA |
CTD |
PMID:37567420 |
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NCBI chr 9:38,805,864...38,913,681
Ensembl chr 9:38,805,864...38,913,672
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G |
Fam78b |
family with sequence similarity 78, member B |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of FAM78B mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM78B mRNA] |
CTD |
PMID:33448797 |
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NCBI chr13:79,162,393...79,250,958
Ensembl chr13:79,162,228...79,250,500
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G |
Fam83c |
family with sequence similarity 83, member C |
multiple interactions increases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in increased expression of FAM83C mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 3:144,333,736...144,339,758
Ensembl chr 3:144,332,982...144,339,802
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G |
Fam98c |
family with sequence similarity 98, member C |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of FAM98C mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM98C mRNA] |
CTD |
PMID:33448797 |
|
NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385
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G |
Fas |
Fas cell surface death receptor |
increases expression decreases expression multiple interactions |
ISO |
Glucose results in increased expression of FAS mRNA; Glucose results in increased expression of FAS protein Glucose results in decreased expression of FAS mRNA dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]]; dorsomorphin inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS protein]]; platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]; platycodin D inhibits the reaction [Glucose results in increased expression of FAS protein]; STO 609 inhibits the reaction [platycodin D inhibits the reaction [Glucose results in increased expression of FAS mRNA]] |
CTD |
PMID:23319015 PMID:31655124 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of FASLG mRNA [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FASL mRNA |
CTD |
PMID:31655124 PMID:37567420 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
increases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of FASN mRNA Allopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]; Glucose promotes the reaction [SREBF1 protein binds to FASN promoter]; Quercetin inhibits the reaction [Glucose results in increased expression of FASN protein] [Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides; [INS protein co-treated with Glucose] results in increased expression of FASN mRNA; [Resveratrol results in increased activity of SIRT1 protein] inhibits the reaction [[Glucose results in increased expression of FASN protein] which results in increased abundance of Triglycerides]; Allopurinol inhibits the reaction [Glucose results in increased expression of FASN protein]; PRKAA2 protein promotes the reaction [SIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]]; Quercetin inhibits the reaction [Glucose results in increased expression of FASN protein]; SIRT1 protein inhibits the reaction [Glucose results in increased expression of FASN protein]; SRT1720 inhibits the reaction [[INS protein co-treated with Glucose] results in increased expression of FASN mRNA] |
CTD |
PMID:15066988 PMID:18482975 PMID:19724016 PMID:22031849 PMID:23647015 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fat3 |
FAT atypical cadherin 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FAT3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAT3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135
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G |
Faxc |
failed axon connections homolog, metaxin like GST domain containing |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FAXC mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
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G |
Fbp2 |
fructose-bisphosphatase 2 |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FBP2 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fbxl13 |
F-box and leucine-rich repeat protein 13 |
increases expression |
ISO |
Glucose results in increased expression of FBXL13 mRNA |
CTD |
PMID:31525975 |
|
NCBI chr 4:13,414,880...13,607,079
Ensembl chr 4:13,414,926...13,641,494
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions increases expression |
ISO |
FBXO32 protein affects the reaction [Glucose results in decreased expression of KCNN2 protein] Glucose results in increased expression of FBXO32 protein |
CTD |
PMID:30635400 |
|
NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fbxo47 |
F-box protein 47 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FBXO47 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr10:82,849,514...82,880,337
Ensembl chr10:82,849,730...82,879,538
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G |
Fbxo48 |
F-box protein 48 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FBXO48 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FBXO48 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314
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G |
Fbxw12 |
F-box and WD repeat domain containing 12 |
increases expression |
ISO |
Glucose results in increased expression of FBXW12 |
CTD |
PMID:36073553 |
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NCBI chr 8:109,782,315...109,802,086
Ensembl chr 8:109,786,815...109,801,813
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G |
Fcer1g |
Fc epsilon receptor Ig |
decreases expression |
ISO |
Glucose results in decreased expression of FCER1G mRNA |
CTD |
PMID:31525975 |
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NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
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G |
Fcgr3a |
Fc gamma receptor 3A |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of FCGR4 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
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G |
Fcho1 |
FCH and mu domain containing endocytic adaptor 1 |
multiple interactions decreases expression |
ISO |
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FCHO1 mRNA] |
CTD |
PMID:33448797 |
|
NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
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G |
Fcrlb |
Fc receptor-like B |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FCRLB mRNA |
CTD |
PMID:37567420 |
|
NCBI chr13:83,148,685...83,157,157
Ensembl chr13:83,149,751...83,155,957
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G |
Fen1 |
flap structure-specific endonuclease 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in decreased expression of FEN1 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
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G |
Fendrr |
FOXF1 adjacent non-coding developmental regulatory RNA |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FENDRR mRNA |
CTD |
PMID:37567420 |
|
NCBI chr19:49,127,225...49,152,780
Ensembl chr19:49,121,214...49,153,240
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G |
Ffar1 |
free fatty acid receptor 1 |
decreases expression multiple interactions |
EXP ISO |
Glucose results in decreased expression of FFAR1 mRNA [FFAR1 protein affects the susceptibility to Dietary Fats] affects the reaction [Glucose results in increased secretion of INS1 protein]; FFAR1 protein affects the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:24349266 PMID:37217659 |
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NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272
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G |
Ffar3 |
free fatty acid receptor 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of FFAR3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FFAR3 mRNA |
CTD |
PMID:37567420 |
|
NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression multiple interactions decreases expression |
ISO |
Glucose results in increased expression of FGF1 mRNA fucoxanthin inhibits the reaction [Glucose results in decreased expression of FGF1 mRNA] |
CTD |
PMID:31655124 PMID:33448797 |
|
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression multiple interactions decreases expression |
EXP ISO |
Glucose results in increased expression of FGF2 mRNA; Glucose results in increased expression of FGF2 protein Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] Glucose results in decreased expression of FGF2 mRNA |
CTD |
PMID:1518840 PMID:19759273 PMID:31655124 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
affects uptake increases secretion multiple interactions increases expression |
ISO |
FGF21 protein affects the uptake of Glucose Glucose results in increased secretion of FGF21 protein indolo(3,2-b)carbazole inhibits the reaction [Glucose deficiency results in increased expression of FGF21 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Glucose deficiency results in increased expression of FGF21 mRNA] indolo(3,2-b)carbazole inhibits the reaction [Glucose results in increased expression of FGF21 mRNA]; Tetrachlorodibenzodioxin inhibits the reaction [Glucose results in increased expression of FGF21 mRNA] |
CTD |
PMID:15902306 PMID:27226639 PMID:28123933 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgf7 |
fibroblast growth factor 7 |
affects transport |
ISO |
FGF7 protein affects the transport of Glucose |
CTD |
PMID:12757114 |
|
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgg |
fibrinogen gamma chain |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FGG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Fgl2 |
fibrinogen-like 2 |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of FGL2 mRNA fucoxanthin inhibits the reaction [Glucose results in increased expression of FGL2 mRNA] |
CTD |
PMID:33448797 |
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NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
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G |
Fhad1 |
forkhead associated phosphopeptide binding domain 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FHAD1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:154,191,593...154,310,442
Ensembl chr 5:154,191,745...154,310,354
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G |
Fis1 |
fission, mitochondrial 1 |
increases expression multiple interactions |
EXP ISO |
Glucose results in increased expression of FIS1 protein [Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA; Melatonin inhibits the reaction [[Glucose co-treated with Deferoxamine] results in increased expression of FIS1 mRNA] cinnamic acid inhibits the reaction [Glucose results in increased expression of FIS1 protein]; Metformin inhibits the reaction [Glucose results in increased expression of FIS1 protein] |
CTD |
PMID:27684054 PMID:30144576 PMID:33962019 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Flg |
filaggrin |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of FLG mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:178,884,793...178,912,986
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G |
Flg2 |
filaggrin 2 |
decreases methylation decreases expression |
ISO |
Glucose results in decreased methylation of FLG2 promoter Glucose results in decreased expression of FLG2 mRNA |
CTD |
PMID:31525975 |
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NCBI chr 2:178,789,792...178,802,232
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
decreases expression multiple interactions |
ISO |
Glucose results in decreased expression of FLT1 mRNA; Glucose results in decreased expression of FLT1 protein [Glucose co-treated with ICG 001] results in decreased expression of FLT1 protein; Panax notoginseng extract inhibits the reaction [[Glucose co-treated with ICG 001] results in decreased expression of FLT1 protein]; Panax notoginseng extract inhibits the reaction [Glucose results in decreased expression of FLT1 protein] |
CTD |
PMID:31655124 PMID:35385194 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Fmo3 |
flavin containing dimethylaniline monoxygenase 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FMO3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
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G |
Fn1 |
fibronectin 1 |
increases expression increases secretion multiple interactions decreases expression decreases secretion |
ISO EXP |
Glucose results in increased expression of FN1 mRNA; Glucose results in increased expression of FN1 protein Glucose results in increased secretion of FN1 protein 3-aminobenzamide inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; 4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Glucose results in increased secretion of FN1 protein]; [Glucose results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased secretion of FN1 protein; acetovanillone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; AKT activator SC79 inhibits the reaction [FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]]; alpha-Tocopherol inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; Bosentan inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Bosentan inhibits the reaction [Glucose results in increased expression of FN1 protein]; BQ 788 inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; calphostin C inhibits the reaction [Glucose results in increased secretion of FN1 protein]; chelerythrine inhibits the reaction [Glucose results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Curcumin inhibits the reaction [Glucose results in increased expression of FN1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased secretion of FN1 protein]; DKK1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC1 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; ERCC4 protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; gingerol inhibits the reaction [Glucose results in increased secretion of FN1 protein]; Glucose results in increased expression of and results in increased secretion of FN1 protein; Indomethacin inhibits the reaction [Glucose results in increased secretion of FN1 protein]; MAPK14 protein promotes the reaction [Glucose results in increased secretion of FN1 protein]; MIR142 affects the reaction [TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of FN1 protein]]; MIR142 inhibits the reaction [Glucose results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; Rotenone inhibits the reaction [Glucose results in increased secretion of FN1 protein]; sitaxsentan inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SN50 peptide inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SN50 peptide inhibits the reaction [Glucose results in increased expression of FN1 protein]; SOX6 protein inhibits the reaction [MIR142 inhibits the reaction [Glucose results in increased expression of FN1 protein]]; TAOK1 mRNA alternative form affects the reaction [Glucose results in increased expression of FN1 protein]; trichostatin A inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; Troglitazone inhibits the reaction [Glucose results in increased expression of FN1 mRNA] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 protein]]; Enalaprilat inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; NFE2L2 protein affects the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]]; Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SMARCA4A protein inhibits the reaction [Glucose results in increased expression of FN1 protein]; TXNIP promotes the reaction [Glucose results in increased expression of FN1 mRNA] Glucose results in decreased expression of FN1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; [[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein; [Glucose results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1; [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; [sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein; acetovanillone inhibits the reaction [Glucose results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of FN1 protein]; cinnamaldehyde inhibits the reaction [Glucose results in increased expression of FN1 protein]; CYBA protein promotes the reaction [Glucose results in increased expression of FN1 protein]; diphenyleneiodonium inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; diphenyliodonium inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; farrerol inhibits the reaction [Glucose results in increased expression of FN1 protein]; HIF1A protein affects the reaction [Glucose results in increased expression of FN1 protein]; LY2109761 inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; manumycin inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; MIR217 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; N,N-dimethylsphingosine inhibits the reaction [Glucose results in increased expression of FN1 protein]; NCF1 protein promotes the reaction [Glucose results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [[[[Glucose results in increased expression of CYBA protein] co-treated with [Glucose results in increased expression of NCF1 protein]] results in increased chemical synthesis of Reactive Oxygen Species] which results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]; rhodioloside inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; SB 203580 inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]; SIRT1 protein affects the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of FN1 protein]]; SPHK1 mRNA affects the reaction [Glucose results in increased expression of FN1 protein]; SPHK1 protein inhibits the reaction [Glucose results in increased expression of FN1 protein]; Superoxides affects the reaction [Glucose results in increased expression of FN1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of FN1 mRNA]; TXNIP protein affects the reaction [Glucose results in increased expression of FN1 protein]; Y 27632 inhibits the reaction [Glucose results in increased expression of FN1 protein] Glucose deficiency results in decreased secretion of FN1 protein Glucose results in decreased expression of FN1 mRNA |
CTD |
PMID:9225831 PMID:12388107 PMID:14520012 PMID:15086456 PMID:16320596 PMID:16572112 PMID:17178593 PMID:17199790 PMID:19765649 PMID:20060012 PMID:21829520 PMID:21998146 PMID:22228707 PMID:22245600 PMID:22406263 PMID:23376009 PMID:24802182 PMID:26045780 PMID:26891083 PMID:29031534 PMID:29163160 PMID:31494106 PMID:31655124 PMID:31838053 PMID:33270355 PMID:38124441 More...
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Folr1 |
folate receptor alpha |
decreases expression |
ISO |
Glucose results in decreased expression of FOLR1 mRNA |
CTD |
PMID:19616087 |
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NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO EXP |
Glucose results in increased expression of FOS mRNA [Glucose co-treated with Lipopolysaccharides] results in increased expression of FOS protein; MIR1231 inhibits the reaction [Glucose results in increased expression of FOS protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of FOS protein] Dactinomycin inhibits the reaction [Glucose results in increased expression of FOS mRNA]; Glucose affects the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA] |
CTD |
PMID:10723097 PMID:11123204 PMID:11557636 PMID:17178593 PMID:18180316 PMID:38156429 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Glucose results in increased expression of FOSL1 mRNA Glucose promotes the reaction [AGT protein results in increased expression of FOSL1 mRNA] |
CTD |
PMID:17178593 PMID:19225232 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression |
ISO |
Glucose results in increased expression of FOSL2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxa2 |
forkhead box A2 |
multiple interactions |
ISO |
[Metformin co-treated with Glucose] affects the localization of FOXA2 protein |
CTD |
PMID:16489446 |
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NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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G |
Foxa3 |
forkhead box A3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FOXA3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
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G |
Foxf2 |
forkhead box F2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FOXF2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176
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G |
Foxm1 |
forkhead box M1 |
increases expression |
ISO |
Glucose results in increased expression of FOXM1 mRNA |
CTD |
PMID:32942007 |
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NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
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G |
Foxo1 |
forkhead box O1 |
increases abundance multiple interactions decreases response to substance |
EXP ISO |
FOXO1 protein mutant form results in increased abundance of Glucose; FOXO1 protein results in increased abundance of Glucose 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO1 protein]]; Acetylcysteine inhibits the reaction [Glucose affects the localization of FOXO1 protein]; Calcitriol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO1 protein]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of BGLAP mRNA]]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 mRNA]]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of RUNX2 protein]]; FOXO1 protein inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in increased expression of BECN1 protein]]; Glucose results in decreased phosphorylation of and affects the localization of FOXO1 protein FOXO1 protein results in decreased susceptibility to Glucose Glucose results in increased acetylation of and results in decreased activity of FOXO1 protein; SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein] FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]; FOXO1 protein inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]; FOXO1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 mRNA]]; FOXO1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of ADIPOR1 protein]]; Glucose results in increased phosphorylation of and results in decreased activity of FOXO1 protein; INS1 protein inhibits the reaction [FOXO1 protein results in increased abundance of Glucose]; INS1 protein promotes the reaction [FOXO1 protein mutant form results in increased abundance of Glucose]; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; resveratrol promotes the reaction [FOXO1 protein results in increased abundance of Glucose] |
CTD |
PMID:15788402 PMID:23494737 PMID:24413998 PMID:33450223 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
multiple interactions decreases expression increases phosphorylation increases localization |
ISO EXP |
[[resveratrol results in increased activity of SIRT1 protein] which results in increased phosphorylation of and results in decreased activity of FOXO3 protein] which results in decreased susceptibility to Glucose; AKT1 protein promotes the reaction [Glucose affects the phosphorylation of and affects the activity of FOXO3 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP1 protein]; FOXO3 protein promotes the reaction [Glucose results in increased cleavage of and results in increased activity of CASP3 protein]; Glucose affects the phosphorylation of and affects the activity of FOXO3 protein; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein] polyethylene glycol loxenatide inhibits the reaction [Glucose results in decreased expression of FOXO3 protein] 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Glucose affects the localization of and results in increased phosphorylation of FOXO3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein]]; 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucose affects the localization of and results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]; Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein; Glucose results in increased phosphorylation of and affects the localization of FOXO3 protein; Resveratrol inhibits the reaction [Glucose results in decreased phosphorylation of and affects the localization of FOXO3 protein] Glucose results in increased localization of FOXO3 protein |
CTD |
PMID:20370652 PMID:23090186 PMID:23159718 PMID:25471227 PMID:37417536 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Foxp1 |
forkhead box P1 |
multiple interactions decreases expression |
ISO |
AKT activator SC79 inhibits the reaction [FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of and results in increased secretion of FN1 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of CYBB protein]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; FOXP1 protein inhibits the reaction [Glucose results in increased expression of NOX4 protein]; FOXP1 protein inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein] Glucose results in decreased expression of FOXP1 mRNA; Glucose results in decreased expression of FOXP1 protein |
CTD |
PMID:31494106 |
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NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258
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G |
Frk |
fyn-related Src family tyrosine kinase |
multiple interactions |
ISO |
FRK protein inhibits the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:17179392 |
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NCBI chr20:38,265,416...38,371,038
Ensembl chr20:38,265,280...38,371,114
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G |
Frmd3 |
FERM domain containing 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FRMD3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
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G |
Frmpd3 |
FERM and PDZ domain containing 3 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FRMPD3 mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:103,964,168...104,113,864
Ensembl chr X:104,043,194...104,111,968
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G |
Fsbp |
fibrinogen silencer binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FSBP mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:25,058,003...25,064,276
Ensembl chr 5:25,032,066...25,104,616
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G |
Fsip1 |
fibrous sheath interacting protein 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of FSIP1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:105,074,584...105,217,180
Ensembl chr 3:105,068,543...105,217,167
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions increases expression |
ISO EXP |
FTH1 protein inhibits the reaction [Glucose results in increased abundance of Reactive Oxygen Species] [[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Oxygen] results in increased expression of [FTH1 protein binds to FTL protein] Glucose results in increased expression of FTH1 protein |
CTD |
PMID:16135072 PMID:18931039 PMID:38483099 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions increases expression |
EXP ISO |
[[Oxygen deficiency co-treated with Glucose deficiency] results in increased susceptibility to Oxygen] results in increased expression of [FTH1 protein binds to FTL protein] Glucose results in increased expression of FTL protein Glucose results in increased expression of FTL1 protein |
CTD |
PMID:16135072 PMID:38483099 |
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NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725 Ensembl chr 2:95,936,387...95,939,725
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G |
Fut1 |
fucosyltransferase 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of FUT1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:96,086,934...96,090,352
Ensembl chr 1:96,086,635...96,090,616
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G |
Fut2 |
fucosyltransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in decreased expression of FUT2 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of FUT2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 1:96,119,549...96,139,567
Ensembl chr 1:96,119,371...96,140,360
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G |
Fxyd5 |
FXYD domain-containing ion transport regulator 5 |
increases expression |
ISO |
Glucose results in increased expression of FXYD5 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:86,267,937...86,277,329
Ensembl chr 1:86,267,406...86,277,519
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G |
G3bp1 |
G3BP stress granule assembly factor 1 |
multiple interactions increases uptake |
ISO |
Deoxyglucose inhibits the reaction [G3BP1 protein results in increased uptake of Glucose]; YWHAZ protein affects the reaction [G3BP1 protein results in increased uptake of Glucose] |
CTD |
PMID:35945655 |
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NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions decreases expression increases activity increases expression |
ISO EXP |
Glucose promotes the reaction [[ARNT protein binds to G6PC1 promoter] which results in increased expression of G6PC1 mRNA]; Glucose results in increased stability of and results in increased expression of G6PC1 mRNA Glucose results in decreased expression of G6PC1 mRNA Glucose results in increased activity of G6PC1 protein Glucose results in increased expression of G6PC1 mRNA Metformin inhibits the reaction [Glucose results in increased expression of G6PC1 mRNA]; tungstate inhibits the reaction [Glucose results in increased activity of G6PC1 protein]; Vanadates inhibits the reaction [Glucose results in increased activity of G6PC1 protein] [Glucose co-treated with S 4048] results in increased expression of G6PC1 mRNA |
CTD |
PMID:14988444 PMID:15767253 PMID:16920846 PMID:19576170 PMID:31974165 PMID:36156098 More...
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GABBR2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
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G |
Gabrp |
gamma-aminobutyric acid type A receptor subunit pi |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA |
CTD |
PMID:37567420 |
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NCBI chr10:18,143,031...18,169,595
Ensembl chr10:18,143,038...18,169,516
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G |
Gabrq |
gamma-aminobutyric acid type A receptor subunit theta |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GABRQ mRNA |
CTD |
PMID:37567420 |
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NCBI chr X:150,696,161...150,712,948
Ensembl chr X:150,696,427...150,709,919
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G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions |
EXP |
GAD1 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] |
CTD |
PMID:25966616 |
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NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
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G |
Gadd45g |
growth arrest and DNA-damage-inducible, gamma |
increases expression |
ISO |
Glucose results in increased expression of GADD45G mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
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G |
Galnt16 |
polypeptide N-acetylgalactosaminyltransferase 16 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GALNT16 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
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G |
Galnt2 |
polypeptide N-acetylgalactosaminyltransferase 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GALNT2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813
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G |
Galnt6 |
polypeptide N-acetylgalactosaminyltransferase 6 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GALNT6 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:131,789,836...131,828,077
Ensembl chr 7:131,789,839...131,819,661
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
multiple interactions increases expression increases ADP-ribosylation |
ISO EXP |
SOD2 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]; SOD2 protein inhibits the reaction [Glucose results in decreased activity of and results in increased ADP-ribosylation of GAPDH protein] Glucose results in increased expression of GAPDH mRNA [chloroacetaldehyde results in decreased activity of GAPDH protein] which results in decreased chemical synthesis of Glucose; UCP1 protein inhibits the reaction [[Glucose results in increased chemical synthesis of Superoxides] which results in decreased activity of GAPDH protein]; UCP1 protein inhibits the reaction [Glucose results in decreased activity of and results in increased ADP-ribosylation of GAPDH protein] Glucose results in increased ADP-ribosylation of GAPDH protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GAPDH mRNA; PARP1 protein affects the reaction [Glucose results in increased ADP-ribosylation of GAPDH protein] |
CTD |
PMID:7826318 PMID:11050244 PMID:14523042 PMID:19733226 PMID:37567420 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gask1b |
golgi associated kinase 1B |
decreases expression |
ISO |
Glucose results in decreased expression of GASK1B mRNA |
CTD |
PMID:33448797 |
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NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
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G |
Gast |
gastrin |
increases secretion |
EXP |
Glucose results in increased secretion of GAST protein |
CTD |
PMID:19208342 |
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NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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G |
Gata4 |
GATA binding protein 4 |
increases metabolic processing |
ISO |
GATA4 protein results in increased metabolism of Glucose |
CTD |
PMID:34087332 |
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NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gbp2 |
guanylate binding protein 2 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP2 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
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G |
Gbp4 |
guanylate binding protein 4 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP3 mRNA; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP4 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
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G |
Gbp7 |
guanylate binding protein 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GBP7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278
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G |
Gc |
GC, vitamin D binding protein |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GC mRNA |
CTD |
PMID:37567420 |
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NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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G |
Gcg |
glucagon |
multiple interactions increases secretion increases abundance decreases secretion |
ISO EXP |
Glucose inhibits the reaction [[Niacin results in decreased abundance of Fatty Acids, Nonesterified] which results in increased secretion of GCG protein] [GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; isosteviol inhibits the reaction [Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein]]; Palmitic Acid promotes the reaction [Glucose results in increased secretion of GCG protein] GCG results in increased abundance of Glucose 9-phenanthrol inhibits the reaction [[GCG protein co-treated with Glucose] results in increased secretion of INS1 protein]; [GCG protein co-treated with Glucose] results in increased secretion of INS1 protein; [GCG protein modified form binds to and results in increased activity of GLP1R protein] promotes the reaction [Glucose results in increased secretion of INS1 protein]; Metformin inhibits the reaction [GCG results in increased abundance of Glucose]; Troglitazone inhibits the reaction [Glucose results in decreased secretion of GCG protein]; Zinc inhibits the reaction [Glucose results in increased secretion of GCG protein] |
CTD |
PMID:838844 PMID:12914525 PMID:15919803 PMID:18669601 PMID:19002567 PMID:22479612 PMID:29098165 More...
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gck |
glucokinase |
multiple interactions increases expression decreases expression |
ISO EXP |
[ebselen co-treated with Glucose] results in increased activity of GCK protein; [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Herbicides] results in increased expression of GCK mRNA; Glucose inhibits the reaction [Alloxan results in decreased expression of GCK mRNA] Glucose results in increased expression of GCK mRNA Glucose results in decreased expression of and affects the localization of GCK protein; Metformin inhibits the reaction [Glucose results in decreased expression of GCK mRNA] |
CTD |
PMID:12137914 PMID:23795780 PMID:24349266 PMID:31974165 PMID:37567420 |
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NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO EXP |
[Glucose co-treated with gastrodin] affects the expression of GCLC mRNA |
CTD |
PMID:33764184 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
EXP ISO |
[Glucose co-treated with gastrodin] affects the expression of GCLM mRNA |
CTD |
PMID:33764184 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcsam |
germinal center-associated, signaling and motility |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of GCSAM mRNA |
CTD |
PMID:37567420 |
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NCBI chr11:55,195,757...55,207,011
Ensembl chr11:55,196,712...55,206,992
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G |
Gdap1l1 |
ganglioside-induced differentiation-associated protein 1-like 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GDAP1L1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711
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G |
Gdf7 |
growth differentiation factor 7 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GDF7 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 6:31,171,495...31,182,484
Ensembl chr 6:31,178,119...31,182,447
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G |
Gem |
GTP binding protein overexpressed in skeletal muscle |
increases expression |
ISO |
Glucose results in increased expression of GEM mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
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G |
Gh1 |
growth hormone 1 |
multiple interactions |
ISO |
GH1 protein promotes the reaction [Glucose results in increased phosphorylation of TBC1D4 protein]; Glucose inhibits the reaction [[Niacin results in decreased abundance of Fatty Acids, Nonesterified] which results in increased secretion of GH1 protein] |
CTD |
PMID:838844 PMID:21559284 |
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NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
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G |
Ghrhr |
growth hormone releasing hormone receptor |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of GHRHR mRNA |
CTD |
PMID:37567420 |
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NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776
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G |
Ghrl |
ghrelin and obestatin prepropeptide |
multiple interactions |
ISO |
[homoeriodictyol co-treated with Glucose] results in increased secretion of GHRL protein |
CTD |
PMID:28834253 |
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NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
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G |
Gja1 |
gap junction protein, alpha 1 |
decreases expression increases degradation multiple interactions increases expression |
ISO EXP |
Glucose results in decreased expression of GJA1 protein Glucose results in increased degradation of GJA1 protein resveratrol inhibits the reaction [Glucose results in increased degradation of GJA1 protein] Glucose results in increased expression of GJA1 mRNA Glucose results in increased expression of GJA1 protein Chloroquine inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased expression of GJA1 protein]]; Chloroquine promotes the reaction [Glucose results in increased expression of GJA1 protein]; Resveratrol inhibits the reaction [Glucose results in increased expression of GJA1 protein] |
CTD |
PMID:17178593 PMID:20578705 PMID:28713934 |
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NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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G |
Gla |
galactosidase, alpha |
increases expression |
ISO |
Glucose results in increased expression of GLA mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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G |
Glb1 |
galactosidase, beta 1 |
increases expression increases activity multiple interactions |
ISO EXP |
Glucose results in increased expression of GLB1 protein Glucose results in increased activity of GLB1 protein NAD inhibits the reaction [Glucose results in increased expression of GLB1 protein]; Niacinamide inhibits the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; resveratrol inhibits the reaction [Glucose results in increased expression of GLB1 protein]; Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]; SIRT1 protein promotes the reaction [NAD inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; SIRT1 protein promotes the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; SIRT1 protein promotes the reaction [Sirolimus inhibits the reaction [Glucose results in increased expression of GLB1 protein]] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytic Acid inhibits the reaction [Glucose results in increased expression of GLB1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]]; CDKN1A protein affects the reaction [Glucose results in increased expression of GLB1 protein]; CDKN2A protein affects the reaction [Glucose results in increased expression of GLB1 protein]; Fluorometholone inhibits the reaction [Glucose results in increased activity of GLB1 protein]; Melatonin inhibits the reaction [Glucose results in increased expression of GLB1 protein]; Phytic Acid inhibits the reaction [Glucose results in increased expression of GLB1 protein]; SIRT3 protein inhibits the reaction [Glucose results in increased expression of GLB1 protein] |
CTD |
PMID:17075048 PMID:22561310 PMID:23494737 PMID:35264022 PMID:38000455 PMID:38483099 More...
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NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Gli1 |
GLI family zinc finger 1 |
multiple interactions increases expression |
ISO |
[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA; [Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of GLI1 mRNA]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased localization of GLI1 protein] Glucose results in increased expression of GLI1 protein |
CTD |
PMID:27481074 PMID:33992720 |
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NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
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G |
Gli2 |
GLI family zinc finger 2 |
affects localization multiple interactions |
ISO |
Glucose affects the localization of GLI2 protein [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in decreased expression of GLI2 mRNA |
CTD |
PMID:33992720 PMID:37567420 |
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NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
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G |
Glipr1 |
GLI pathogenesis-related 1 |
multiple interactions |
ISO |
[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with Glyphosate] results in increased expression of GLIPR1 mRNA |
CTD |
PMID:37567420 |
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NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429
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G |
Glo1 |
glyoxalase 1 |
multiple interactions decreases expression |
ISO EXP |
GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to HMGB1 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A12 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [JUN protein binds to S100A8 promoter]]; GLO1 inhibits the reaction [Glucose promotes the reaction [RELA protein binds to AGER promoter]]; GLO1 inhibits the reaction [Glucose results in decreased expression of GLO1 protein]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of AGER protein]; GLO1 inhibits the reaction [Glucose results in increased expression of and results in increased secretion of HMGB1 protein]; GLO1 inhibits the reaction [Glucose results in increased expression of HMGB1 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A12 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A8 mRNA]; GLO1 inhibits the reaction [Glucose results in increased expression of S100A8 protein]; SOD2 inhibits the reaction [Glucose results in decreased expression of GLO1 protein]; UCP1 inhibits the reaction [Glucose results in decreased expression of GLO1 protein] morroniside inhibits the reaction [Glucose results in decreased expression of GLO1 mRNA]; morroniside inhibits the reaction [Glucose results in decreased expression of GLO1 protein] |
CTD |
PMID:19833897 PMID:32643284 |
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NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
ISO < |