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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-chlorosalicylic acid
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Accession:CHEBI:420128 term browser browse the term
Definition:A monohydroxybenzoic acid that is 2-hydroxybenzoic acid (salicylic acid) in which the hydrogen at position 5 is replaced by chlorine.
Synonyms:related_synonym: 2-Hydroxy-5-chlorobenzoic acid;   5 CSA;   5-Chloro-2-hydroxybenzoic acid;   Formula=C7H5ClO3;   InChI=1S/C7H5ClO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,(H,10,11);   InChIKey=NKBASRXWGAGQDP-UHFFFAOYSA-N;   SMILES=OC(=O)c1cc(Cl)ccc1O
 xref: AGR:IND43635496;   CAS:321-14-2;   Gmelin:561203;   PMID:1650428;   PMID:18819808;   PMID:1944396;   PMID:20062845;   PMID:21689976;   PMID:22365879;   PMID:22476141;   PMID:28166217;   Patent:CN101684061;   Reaxys:2046665
 cyclic_relationship: is_conjugate_acid_of CHEBI:59131



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niclosamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein increases expression ISO Niclosamide results in increased expression of A1BG mRNA CTD PMID:36318118 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 decreases expression ISO Niclosamide results in decreased expression of ABCA12 mRNA CTD PMID:36318118 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression ISO Niclosamide results in decreased expression of ABCC9 mRNA CTD PMID:36318118 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 increases expression ISO Niclosamide results in increased expression of ABCG4 mRNA CTD PMID:36318118 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881
JBrowse link
G Abhd1 abhydrolase domain containing 1 increases expression ISO Niclosamide results in increased expression of ABHD1 mRNA CTD PMID:36318118 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14b abhydrolase domain containing 14b increases expression ISO Niclosamide results in increased expression of ABHD14B mRNA CTD PMID:36318118 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression ISO Niclosamide results in decreased expression of ACACA mRNA CTD PMID:22576131 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]
CTD PMID:26792726 PMID:28824321 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Niclosamide results in decreased expression of ACSL1 mRNA CTD PMID:22576131 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of ACTA2 protein]
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of ACTA2 protein]; Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of ACTA2 protein]
Niclosamide results in decreased expression of ACTA2 mRNA; Niclosamide results in decreased expression of ACTA2 protein
CTD PMID:26643609 PMID:28318631 PMID:34118929 PMID:35115509 PMID:36870549 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 decreases expression ISO Niclosamide results in decreased expression of ADAMTS17 mRNA CTD PMID:36318118 NCBI chr 1:120,445,800...120,768,204
Ensembl chr 1:120,445,749...120,768,202
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO Niclosamide results in decreased expression of ADH4 mRNA CTD PMID:28284560 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adm2 adrenomedullin 2 increases expression ISO Niclosamide results in increased expression of ADM2 mRNA CTD PMID:36318118 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
JBrowse link
G Adra2a adrenoceptor alpha 2A decreases expression ISO Niclosamide results in decreased expression of ADRA2A mRNA CTD PMID:36318118 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of AFP protein]] CTD PMID:32961231 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agbl3 AGBL carboxypeptidase 3 decreases expression ISO Niclosamide results in decreased expression of AGBL3 mRNA CTD PMID:36318118 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases cleavage ISO Niclosamide results in increased cleavage of AIFM1 protein CTD PMID:22576131 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akna AT-hook transcription factor increases expression ISO Niclosamide results in increased expression of AKNA mRNA CTD PMID:36318118 NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
multiple interactions
ISO Niclosamide results in increased expression of AKT1 mRNA
Niclosamide inhibits the reaction [TNF protein results in increased activity of AKT1 protein]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased phosphorylation of AKT1 protein]
CTD PMID:20215516 PMID:26792726 PMID:29843133 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression ISO Niclosamide results in decreased expression of ALDH1A1 protein CTD PMID:24736023 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO Niclosamide results in increased expression of ALDH6A1 mRNA CTD PMID:36318118 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression ISO Niclosamide results in increased expression of ALDOB mRNA CTD PMID:22576131 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression
increases expression
ISO Niclosamide results in decreased expression of ALDOC mRNA
Niclosamide results in increased expression of ALDOC mRNA
CTD PMID:22576131 PMID:36318118 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Alkbh7 alkB homolog 7 increases expression ISO Niclosamide results in increased expression of ALKBH7 mRNA CTD PMID:36318118 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression
decreases response to substance
multiple interactions
ISO Niclosamide results in increased expression of ALOX12B mRNA
ALOX12B protein results in decreased susceptibility to Niclosamide
TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX12B mRNA]
CTD PMID:30258081 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
increases expression
decreases response to substance
ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of ALOX5 mRNA]
ALOX5 protein results in decreased susceptibility to Niclosamide
CTD PMID:30258081 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated decreases expression ISO Niclosamide results in decreased expression of ALPL mRNA CTD PMID:28824321 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 increases expression ISO Niclosamide results in increased expression of AMHR2 mRNA CTD PMID:36318118 NCBI chr 7:133,579,152...133,588,874
Ensembl chr 7:133,579,393...133,588,258
JBrowse link
G Amot angiomotin increases expression ISO Niclosamide results in increased expression of AMOT mRNA CTD PMID:36318118 NCBI chr  X:108,982,399...109,041,265
Ensembl chr  X:108,984,022...109,041,272
JBrowse link
G Ank3 ankyrin 3 increases expression ISO Niclosamide results in increased expression of ANK3 mRNA CTD PMID:36318118 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Ankmy2 ankyrin repeat and MYND domain containing 2 increases expression ISO Niclosamide results in increased expression of ANKMY2 mRNA CTD PMID:36318118 NCBI chr 6:52,888,959...52,930,343
Ensembl chr 6:52,888,963...52,930,394
JBrowse link
G Ankrd12 ankyrin repeat domain 12 increases expression ISO Niclosamide results in increased expression of ANKRD12 mRNA CTD PMID:36318118 NCBI chr 9:105,583,273...105,687,957
Ensembl chr 9:105,584,065...105,687,911
JBrowse link
G Ankrd34a ankyrin repeat domain 34A increases expression ISO Niclosamide results in increased expression of ANKRD34A mRNA CTD PMID:36318118 NCBI chr 2:184,129,830...184,135,075
Ensembl chr 2:184,129,238...184,135,116
JBrowse link
G Anxa4 annexin A4 increases expression ISO Niclosamide results in increased expression of ANXA4 mRNA CTD PMID:36318118 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Niclosamide results in decreased expression of AP1S3 mRNA CTD PMID:36318118 NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G Aplnr apelin receptor decreases expression ISO Niclosamide results in decreased expression of APLNR mRNA CTD PMID:36318118 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apof apolipoprotein F decreases expression ISO Niclosamide results in decreased expression of APOF mRNA CTD PMID:28284560 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
ISO [enzalutamide co-treated with Niclosamide] results in decreased expression of AR protein; [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]] which results in decreased expression of KLK3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein alternative form]; bicalutamide promotes the reaction [Niclosamide results in decreased expression of AR protein]; Niclosamide inhibits the reaction [AR protein alternative form binds to KLK3 promoter]; Niclosamide inhibits the reaction [AR protein alternative form results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]; Niclosamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Niclosamide results in decreased expression of and results in increased degradation of AR protein alternative form
Niclosamide results in decreased expression of AR protein; Niclosamide results in decreased expression of AR protein alternative form
CTD PMID:24740322 PMID:25970160 PMID:28500234 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Araf A-Raf proto-oncogene, serine/threonine kinase decreases expression ISO Niclosamide analog results in decreased expression of ARAF protein; Niclosamide results in decreased expression of ARAF protein CTD PMID:28284560 NCBI chr  X:1,227,392...1,292,356
Ensembl chr  X:1,227,392...1,239,073
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Niclosamide results in increased expression of ARHGDIB mRNA CTD PMID:36318118 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Armcx1 armadillo repeat containing, X-linked 1 increases expression ISO Niclosamide results in increased expression of ARMCX1 mRNA CTD PMID:36318118 NCBI chr  X:97,898,969...97,902,874
Ensembl chr  X:97,898,883...97,903,299
JBrowse link
G Arrdc2 arrestin domain containing 2 increases expression ISO Niclosamide results in increased expression of ARRDC2 mRNA CTD PMID:36318118 NCBI chr16:18,601,897...18,606,029
Ensembl chr16:18,601,897...18,606,029
JBrowse link
G Asf1b anti-silencing function 1B histone chaperone decreases expression ISO Niclosamide results in decreased expression of ASF1B mRNA CTD PMID:28284560 NCBI chr19:24,181,024...24,195,604
Ensembl chr19:24,181,028...24,195,549
JBrowse link
G Atcay ATCAY kinesin light chain interacting caytaxin increases expression ISO Niclosamide results in increased expression of ATCAY mRNA CTD PMID:36318118 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Niclosamide results in increased expression of ATF3 mRNA; Niclosamide results in increased expression of ATF3 protein
ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]; ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]
CTD PMID:26917416 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Niclosamide results in increased expression of ATF4 mRNA; Niclosamide results in increased expression of ATF4 protein CTD PMID:26917416 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atosb atos homolog B increases expression ISO Niclosamide results in increased expression of ATOSB mRNA CTD PMID:36318118 NCBI chr 5:57,260,839...57,274,524
Ensembl chr 5:57,260,841...57,268,892
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Niclosamide results in increased expression of ATP2A3 mRNA CTD PMID:36318118 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression ISO Niclosamide results in increased expression of ATP5F1A mRNA CTD PMID:22576131 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta increases expression ISO Niclosamide results in increased expression of ATP5F1D mRNA CTD PMID:22576131 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression ISO Niclosamide results in decreased expression of ATP5MC3 mRNA CTD PMID:22576131 NCBI chr 3:58,810,535...58,813,185
Ensembl chr 3:58,810,535...58,814,279
JBrowse link
G Atp5mf ATP synthase membrane subunit f decreases expression ISO Niclosamide results in decreased expression of ATP5MF mRNA CTD PMID:22576131 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
JBrowse link
G Atp5mg ATP synthase membrane subunit G decreases expression ISO Niclosamide results in decreased expression of ATP5MG mRNA CTD PMID:22576131 NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b decreases expression ISO Niclosamide results in decreased expression of ATP5PB mRNA CTD PMID:22576131 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp6ap1 ATPase H+ transporting accessory protein 1 decreases expression ISO Niclosamide results in decreased expression of ATP6AP1 mRNA CTD PMID:22576131 NCBI chr  X:152,079,954...152,087,034
Ensembl chr  X:152,079,865...152,087,034
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ATP6V0D2 mRNA] CTD PMID:26792726 NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354
JBrowse link
G Atpsckmt ATP synthase c subunit lysine N-methyltransferase decreases expression ISO Niclosamide results in decreased expression of ATPSCKMT mRNA CTD PMID:36318118 NCBI chr 2:82,603,086...82,618,325
Ensembl chr 2:82,603,009...82,618,308
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Niclosamide results in decreased expression of AURKB mRNA CTD PMID:28284560 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Avpi1 arginine vasopressin-induced 1 increases expression ISO Niclosamide results in increased expression of AVPI1 mRNA CTD PMID:36318118 NCBI chr 1:240,930,236...240,936,154
Ensembl chr 1:240,930,236...240,936,154
JBrowse link
G Axin2 axin 2 multiple interactions
decreases expression
ISO Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of AXIN2 mRNA]
Niclosamide results in decreased expression of AXIN2 mRNA; Niclosamide results in decreased expression of AXIN2 protein
CTD PMID:22576131 PMID:24534281 PMID:24552774 PMID:24736023 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 increases expression ISO Niclosamide results in increased expression of B3GNT7 mRNA CTD PMID:36318118 NCBI chr 9:86,956,220...86,960,171
Ensembl chr 9:86,956,220...86,960,170
JBrowse link
G B3gnt9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 increases expression ISO Niclosamide results in increased expression of B3GNT9 mRNA CTD PMID:36318118 NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAD mRNA CTD PMID:25988281 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [Niclosamide binds to Polyethyleneimine] which results in increased expression of BAK1 mRNA CTD PMID:25988281 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
multiple interactions
ISO Niclosamide results in increased expression of BAX protein
Niclosamide results in decreased expression of BAX protein
[Niclosamide binds to Polyethyleneimine] which results in increased expression of BAX mRNA; [Niclosamide co-treated with bicalutamide] results in increased expression of BAX protein; bicalutamide inhibits the reaction [Niclosamide results in decreased expression of BAX protein]
CTD PMID:25634333 PMID:25988281 PMID:26703449 PMID:28500234 PMID:35115509 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions
increases expression
ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of BBC3 mRNA] CTD PMID:30258081 PMID:36318118 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 increases expression ISO Niclosamide results in increased expression of BBS2 mRNA CTD PMID:36318118 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO Niclosamide analog results in decreased expression of BCL2 protein; Niclosamide results in decreased expression of BCL2 protein
[Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2 mRNA; [Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2 protein]; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2 protein]
CTD PMID:20215516 PMID:23894143 PMID:25634333 PMID:25988281 PMID:26116531 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO [Niclosamide binds to Polyethyleneimine] which results in decreased expression of BCL2L1 mRNA; bicalutamide promotes the reaction [Niclosamide results in decreased expression of BCL2L1 protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of BCL2L1 protein]
Niclosamide analog results in decreased expression of BCL2L1 protein; Niclosamide results in decreased expression of BCL2L1 protein
CTD PMID:20215516 PMID:25988281 PMID:26116531 PMID:28284560 PMID:28500234 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Bcl2l2 Bcl2-like 2 decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of BCL2L2 protein
[Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]] which results in increased susceptibility to Erlotinib Hydrochloride; Niclosamide inhibits the reaction [Erlotinib Hydrochloride results in increased expression of BCL2L2 protein]
CTD PMID:23894143 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression ISO Niclosamide results in increased expression of BCL3 mRNA CTD PMID:36318118 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions
increases expression
ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]
Niclosamide results in increased expression of BCL6 mRNA
CTD PMID:33632240 PMID:36318118 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression ISO Niclosamide results in increased expression of BCL6B mRNA CTD PMID:36318118 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bcl9 BCL9, transcription coactivator decreases expression EXP Niclosamide results in decreased expression of BCL9 mRNA CTD PMID:27338550 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435
JBrowse link
G Bcorl1 BCL6 co-repressor-like 1 increases expression ISO Niclosamide results in increased expression of BCORL1 mRNA CTD PMID:36318118 NCBI chr  X:127,516,504...127,584,529
Ensembl chr  X:127,537,538...127,584,087
JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like increases expression ISO Niclosamide results in increased expression of BET1L mRNA CTD PMID:36318118 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040
JBrowse link
G Bgn biglycan increases expression ISO Niclosamide results in increased expression of BGN mRNA CTD PMID:36318118 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Niclosamide results in increased expression of BHLHE40 mRNA CTD PMID:36318118 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
affects expression
ISO enzalutamide promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]
Niclosamide analog results in decreased expression of BIRC5 protein; Niclosamide results in decreased expression of BIRC5 mRNA; Niclosamide results in decreased expression of BIRC5 protein
Niclosamide affects the expression of BIRC5 protein
CTD PMID:24552774 PMID:24736023 PMID:25970160 PMID:28284560 PMID:28500234 More... NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Niclosamide results in increased expression of BMF mRNA CTD PMID:36318118 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Borcs6 BLOC-1 related complex subunit 6 increases expression ISO Niclosamide results in increased expression of BORCS6 mRNA CTD PMID:36318118 NCBI chr10:53,760,504...53,762,358
Ensembl chr10:53,758,093...53,762,632
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression
decreases phosphorylation
ISO Niclosamide analog results in decreased expression of BRAF protein; Niclosamide results in decreased expression of BRAF protein
Niclosamide analog results in decreased phosphorylation of BRAF protein
CTD PMID:28284560 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Btbd7 BTB domain containing 7 decreases expression ISO Niclosamide results in decreased expression of BTBD7 mRNA CTD PMID:36318118 NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Niclosamide results in increased expression of BTG2 mRNA CTD PMID:36318118 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G C13h1orf105 similar to human chromosome 1 open reading frame 105 decreases expression ISO Niclosamide results in decreased expression of C1ORF105 mRNA CTD PMID:36318118 NCBI chr13:74,313,320...74,356,322
Ensembl chr13:74,313,322...74,356,322
JBrowse link
G C16h8orf48 similar to human chromosome 8 open reading frame 48 decreases expression ISO Niclosamide results in decreased expression of C8ORF48 mRNA CTD PMID:36318118 NCBI chr16:55,244,744...55,246,642
Ensembl chr16:55,236,322...55,246,650
JBrowse link
G C19h16orf86 similar to human chromosome 16 open reading frame 86 increases expression ISO Niclosamide results in increased expression of C16ORF86 mRNA CTD PMID:36318118 NCBI chr19:33,596,591...33,598,703
Ensembl chr19:33,595,995...33,598,521
JBrowse link
G C1ql4 complement C1q like 4 increases expression ISO Niclosamide results in increased expression of C1QL4 mRNA CTD PMID:36318118 NCBI chr 7:130,243,606...130,246,678
Ensembl chr 7:130,243,606...130,246,678
JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Niclosamide results in decreased expression of CABLES2 mRNA CTD PMID:36318118 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression ISO Niclosamide results in increased expression of CACNA1E mRNA CTD PMID:36318118 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression ISO Niclosamide results in increased expression of CACNA1H mRNA CTD PMID:36318118 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 increases expression ISO Niclosamide results in increased expression of CACNG1 mRNA CTD PMID:36318118 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Niclosamide results in increased expression of CAMK2A mRNA CTD PMID:36318118 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camsap3 calmodulin regulated spectrin-associated protein family, member 3 increases expression ISO Niclosamide results in increased expression of CAMSAP3 mRNA CTD PMID:36318118 NCBI chr12:1,643,062...1,666,685
Ensembl chr12:1,643,251...1,666,685
JBrowse link
G Caps calcyphosine increases expression ISO Niclosamide results in increased expression of CAPS mRNA CTD PMID:36318118 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Niclosamide co-treated with Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CASP1 protein
Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP1 protein]
CTD PMID:33524445 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
decreases expression
increases expression
ISO
EXP
Niclosamide results in increased cleavage of CASP3 protein
7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; [Niclosamide binds to Polyethyleneimine] which results in increased expression of CASP3 mRNA; ATF3 protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid inhibits the reaction [Niclosamide results in increased cleavage of CASP3 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP3 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of CASP3 protein]
Niclosamide results in decreased expression of CASP3 protein
Niclosamide results in increased expression of CASP3 protein modified form
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased expression of CASP3 protein modified form; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]
Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in decreased expression of CASP3 mRNA]]
CTD PMID:20215516 PMID:21871175 PMID:24750999 PMID:25174399 PMID:25634333 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
ISO bicalutamide promotes the reaction [Niclosamide results in increased expression of CASP7 protein modified form] CTD PMID:26116531 PMID:28500234 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases cleavage ISO Niclosamide results in increased cleavage of CASP8 protein CTD PMID:35115509 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
increases expression
ISO TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of CASP9 protein]
Niclosamide results in increased expression of CASP9 mRNA; Niclosamide results in increased expression of CASP9 protein modified form
CTD PMID:26116531 PMID:26703449 PMID:30258081 PMID:36318118 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbx4 chromobox 4 increases expression ISO Niclosamide results in increased expression of CBX4 mRNA CTD PMID:36318118 NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706
JBrowse link
G Ccdc113 coiled-coil domain containing 113 increases expression ISO Niclosamide results in increased expression of CFAP263 mRNA CTD PMID:36318118 NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923
JBrowse link
G Ccdc188 coiled-coil domain containing 188 increases expression ISO Niclosamide results in increased expression of CCDC188 mRNA CTD PMID:36318118 NCBI chr11:82,769,735...82,772,062
Ensembl chr11:82,769,473...82,772,114
JBrowse link
G Ccdc68 coiled-coil domain containing 68 decreases expression ISO Niclosamide results in decreased expression of CCDC68 mRNA CTD PMID:36318118 NCBI chr18:63,541,828...63,584,122
Ensembl chr18:63,541,896...63,584,119
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL2 mRNA]
CTD PMID:24561310 PMID:28318631 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO
EXP
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of CCL20 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CCL20 mRNA]
CTD PMID:28318631 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:24561310 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL5 protein] CTD PMID:24561310 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Niclosamide results in decreased expression of CCNB1 mRNA CTD PMID:28284560 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb3 cyclin B3 decreases expression ISO Niclosamide results in decreased expression of CCNB3 mRNA CTD PMID:36318118 NCBI chr  X:15,478,050...15,543,292
Ensembl chr  X:15,478,065...15,542,885
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
EXP
ISO
Niclosamide inhibits the reaction [Epinephrine results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 mRNA]]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CCND1 protein]]
Niclosamide inhibits the reaction [IL6 protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [TNF protein results in increased expression of CCND1 mRNA]; Niclosamide promotes the reaction [bicalutamide results in decreased expression of CCND1 protein]
Niclosamide analog results in decreased expression of CCND1 protein; Niclosamide results in decreased expression of CCND1 mRNA; Niclosamide results in decreased expression of CCND1 protein
CTD PMID:19160421 PMID:20215516 PMID:24552774 PMID:24736023 PMID:26297436 More... NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnd2 cyclin D2 decreases expression
increases expression
ISO Niclosamide results in decreased expression of CCND2 mRNA
Niclosamide results in increased expression of CCND2 mRNA
CTD PMID:22576131 PMID:27226553 PMID:36318118 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Niclosamide results in decreased expression of CCND3 mRNA CTD PMID:22576131 PMID:27226553 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Niclosamide results in decreased expression of CCNE1 mRNA CTD PMID:36318118 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]
Niclosamide results in decreased expression of CCNE2 mRNA
CTD PMID:27542212 PMID:36318118 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng2 cyclin G2 multiple interactions
increases expression
ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]
Niclosamide results in increased expression of CCNG2 mRNA
CTD PMID:27542212 PMID:36318118 NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 increases expression ISO Niclosamide results in increased expression of CCR10 mRNA CTD PMID:36318118 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
JBrowse link
G Cd27 CD27 molecule increases expression ISO Niclosamide results in increased expression of CD27 mRNA CTD PMID:36318118 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd274 CD274 molecule decreases expression ISO Niclosamide results in decreased expression of CD274 mRNA; Niclosamide results in decreased expression of CD274 protein CTD PMID:35115509 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD40 protein] CTD PMID:24561310 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Niclosamide results in increased expression of CD55 mRNA CTD PMID:36318118 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cd68 Cd68 molecule increases expression ISO Niclosamide results in increased expression of CD68 mRNA CTD PMID:36318118 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD80 protein] CTD PMID:24561310 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Niclosamide inhibits the reaction [Lipopolysaccharides affects the expression of CD86 protein] CTD PMID:24561310 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone multiple interactions ISO CDC37 protein binds to and results in increased susceptibility to Niclosamide analog CTD PMID:28284560 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809
JBrowse link
G Cdc42 cell division cycle 42 decreases expression
decreases phosphorylation
ISO Niclosamide results in decreased expression of CDC42 mRNA
Niclosamide results in decreased phosphorylation of CDC42 protein
CTD PMID:29251334 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
JBrowse link
G Cdc42ep1 CDC42 effector protein 1 increases expression ISO Niclosamide results in increased expression of CDC42EP1 mRNA CTD PMID:36318118 NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Niclosamide results in decreased expression of CDC6 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Niclosamide results in decreased expression of CDCA2 mRNA CTD PMID:28284560 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdca5 cell division cycle associated 5 decreases expression ISO Niclosamide results in decreased expression of CDCA5 mRNA CTD PMID:28284560 NCBI chr 1:203,378,550...203,392,027
Ensembl chr 1:203,378,577...203,392,023
JBrowse link
G Cdca8 cell division cycle associated 8 decreases expression ISO Niclosamide results in decreased expression of CDCA8 mRNA CTD PMID:28284560 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh1 cadherin 1 multiple interactions
increases expression
ISO CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in decreased expression of CDH1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased expression of CDH1 protein]
Niclosamide results in increased expression of CDH1 mRNA; Niclosamide results in increased expression of CDH1 protein
CTD PMID:25174399 PMID:26643609 PMID:30143678 PMID:35115509 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh11 cadherin 11 decreases expression ISO Niclosamide results in decreased expression of CDH11 mRNA CTD PMID:36318118 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh12 cadherin 12 multiple interactions ISO Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of CDH12 protein] CTD PMID:36870549 NCBI chr 2:70,474,679...71,705,369
Ensembl chr 2:70,475,043...71,700,572
JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression
ISO Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased expression of CDH2 protein]
Niclosamide results in decreased expression of CDH2 protein
CTD PMID:26643609 PMID:34118929 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh4 cadherin 4 increases expression ISO Niclosamide results in increased expression of CDH4 mRNA CTD PMID:36318118 NCBI chr 3:166,525,092...167,003,380
Ensembl chr 3:166,525,099...167,003,371
JBrowse link
G Cdh6 cadherin 6 decreases expression ISO Niclosamide results in decreased expression of CDH6 mRNA CTD PMID:36318118 NCBI chr 2:62,079,139...62,225,298
Ensembl chr 2:62,079,137...62,225,228
JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression ISO Niclosamide results in increased expression of CDHR1 mRNA CTD PMID:36318118 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
JBrowse link
G Cdhr2 cadherin-related family member 2 decreases expression ISO Niclosamide results in decreased expression of CDHR2 mRNA CTD PMID:36318118 NCBI chr17:9,876,853...9,913,356
Ensembl chr17:9,876,860...9,912,575
JBrowse link
G Cdk15 cyclin-dependent kinase 15 decreases expression ISO Niclosamide results in decreased expression of CDK15 mRNA CTD PMID:36318118 NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Niclosamide results in decreased expression of CDK2 protein CTD PMID:29031202 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Niclosamide results in decreased expression of CDK4 protein CTD PMID:29031202 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdkl3 cyclin-dependent kinase-like 3 increases expression ISO Niclosamide results in increased expression of CDKL3 mRNA CTD PMID:36318118 NCBI chr10:36,263,212...36,349,268
Ensembl chr10:36,266,977...36,349,268
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO TP53 gene mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA]; TP53 protein mutant form inhibits the reaction [Niclosamide results in increased expression of CDKN1A mRNA] CTD PMID:30258081 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Niclosamide results in decreased expression of CDKN3 mRNA CTD PMID:28284560 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Niclosamide results in increased expression of CEBPB mRNA CTD PMID:36318118 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Niclosamide results in increased expression of CELF6 mRNA CTD PMID:36318118 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041
JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 increases expression ISO Niclosamide results in increased expression of CELSR3 mRNA CTD PMID:28284560 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354
JBrowse link
G Cenpa centromere protein A decreases expression ISO Niclosamide results in decreased expression of CENPA mRNA CTD PMID:28284560 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpo centromere protein O decreases expression ISO Niclosamide results in decreased expression of CENPO mRNA CTD PMID:36318118 NCBI chr 6:27,203,642...27,218,394
Ensembl chr 6:27,188,537...27,218,314
JBrowse link
G Cenpu centromere protein U decreases expression ISO Niclosamide results in decreased expression of CENPU mRNA CTD PMID:36318118 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
JBrowse link
G Cfap70 cilia and flagella associated protein 70 increases expression ISO Niclosamide results in increased expression of CFAP70 mRNA CTD PMID:36318118 NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014
JBrowse link
G Cfp complement factor properdin increases expression ISO Niclosamide results in increased expression of CFP mRNA CTD PMID:28284560 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Niclosamide results in increased expression of CHAC1 mRNA CTD PMID:36318118 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chac2 ChaC glutathione specific gamma-glutamylcyclotransferase 2 decreases expression ISO Niclosamide results in decreased expression of CHAC2 mRNA CTD PMID:36318118 NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression ISO Niclosamide results in decreased expression of CHAF1A mRNA CTD PMID:36318118 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression ISO Niclosamide results in increased expression of CHRNB1 mRNA CTD PMID:36318118 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
JBrowse link
G Chst8 carbohydrate sulfotransferase 8 increases expression ISO Niclosamide results in increased expression of CHST8 mRNA CTD PMID:36318118 NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Niclosamide results in decreased phosphorylation of and affects the localization of CHUK protein CTD PMID:26116531 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Niclosamide results in increased expression of CISH mRNA CTD PMID:36318118 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Clec11a C-type lectin domain containing 11A increases expression ISO Niclosamide results in increased expression of CLEC11A mRNA CTD PMID:36318118 NCBI chr 1:94,800,456...94,809,002
Ensembl chr 1:94,801,496...94,804,633
JBrowse link
G Clip2 CAP-GLY domain containing linker protein 2 increases expression ISO Niclosamide results in increased expression of CLIP2 mRNA CTD PMID:36318118 NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023
JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO Niclosamide results in increased expression of CLIP3 mRNA CTD PMID:36318118 NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184
JBrowse link
G Clspn claspin decreases expression ISO Niclosamide results in decreased expression of CLSPN mRNA CTD PMID:36318118 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Clstn3 calsyntenin 3 increases expression ISO Niclosamide results in increased expression of CLSTN3 mRNA CTD PMID:36318118 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 decreases expression ISO Niclosamide results in decreased expression of CMKLR1 mRNA CTD PMID:36318118 NCBI chr12:42,974,462...43,027,321
Ensembl chr12:42,974,410...43,028,129
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 decreases expression ISO Niclosamide results in decreased expression of CMPK2 mRNA CTD PMID:36318118 NCBI chr 6:43,073,706...43,085,183
Ensembl chr 6:43,073,796...43,085,183
JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression ISO Niclosamide results in increased expression of CNBD2 mRNA CTD PMID:36318118 NCBI chr 3:144,819,166...144,884,825
Ensembl chr 3:144,819,195...144,901,583
JBrowse link
G Cnn1 calponin 1 increases expression ISO Niclosamide results in increased expression of CNN1 mRNA CTD PMID:36318118 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Cnn2 calponin 2 increases expression ISO Niclosamide results in increased expression of CNN2 mRNA CTD PMID:36318118 NCBI chr 7:9,712,505...9,719,678
Ensembl chr 7:9,712,516...9,719,656
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of COL1A1 mRNA
Niclosamide results in decreased expression of COL1A1 protein
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Gemcitabine inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; Niclosamide inhibits the reaction [Gemcitabine results in decreased expression of COL1A1 protein]
CTD PMID:28824321 PMID:35115509 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Niclosamide results in increased expression of COL6A2 mRNA CTD PMID:36318118 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
JBrowse link
G Colec10 collectin subfamily member 10 increases expression ISO Niclosamide results in increased expression of COLEC10 mRNA CTD PMID:28284560 NCBI chr 7:85,744,895...85,806,368
Ensembl chr 7:85,744,895...85,805,675
JBrowse link
G Cox8c cytochrome c oxidase subunit 8C increases expression ISO Niclosamide results in increased expression of COX8C mRNA CTD PMID:36318118 NCBI chr 6:122,028,566...122,029,889
Ensembl chr 6:122,028,566...122,029,889
JBrowse link
G Crb2 crumbs cell polarity complex component 2 increases expression ISO Niclosamide results in increased expression of CRB2 mRNA CTD PMID:36318118 NCBI chr 3:21,542,138...21,564,876
Ensembl chr 3:21,542,221...21,563,294
JBrowse link
G Crebbp CREB binding protein increases expression ISO Niclosamide results in increased expression of CREBBP mRNA CTD PMID:22576131 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Niclosamide results in increased expression of CREBRF mRNA CTD PMID:36318118 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999
JBrowse link
G Crlf1 cytokine receptor-like factor 1 decreases expression ISO Niclosamide results in decreased expression of CRLF1 mRNA CTD PMID:36318118 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Niclosamide results in decreased expression of CROT mRNA CTD PMID:36318118 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Crybb1 crystallin, beta B1 increases expression ISO Niclosamide results in increased expression of CRYBB1 mRNA CTD PMID:36318118 NCBI chr12:44,369,734...44,383,344
Ensembl chr12:44,369,735...44,383,344
JBrowse link
G Cryl1 crystallin, lambda 1 increases expression ISO Niclosamide results in increased expression of CRYL1 mRNA CTD PMID:36318118 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ACP5 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of CASP3 protein modified form]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of TRAF6 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein] CTD PMID:28824321 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA] CTD PMID:27542212 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319
JBrowse link
G Csnk1e casein kinase 1, epsilon increases expression ISO Niclosamide results in increased expression of CSNK1E mRNA CTD PMID:22576131 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 increases expression ISO Niclosamide results in increased expression of CSRNP1 mRNA CTD PMID:28284560 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Niclosamide results in increased expression of CTBP1 mRNA CTD PMID:22576131 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
decreases expression
decreases activity
increases ubiquitination
affects localization
ISO
EXP
Niclosamide results in increased expression of CTNNB1 mRNA
CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of ACTA2 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in decreased expression of COL1A1 protein]; CTNNB1 protein inhibits the reaction [Niclosamide results in increased expression of CDH1 protein]; Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of CTNNB1 protein]; Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]; Niclosamide inhibits the reaction [Lithium Chloride affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of CTNNB1 protein]; Niclosamide inhibits the reaction [WNT3A protein results in increased stability of CTNNB1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of CTNNB1 protein]; Niclosamide results in decreased expression of and results in increased phosphorylation of CTNNB1 protein
Niclosamide analog results in decreased expression of CTNNB1 protein; Niclosamide results in decreased expression of CTNNB1 protein
Niclosamide inhibits the reaction [Epinephrine results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of CTNNB1 protein]]
Niclosamide results in decreased activity of CTNNB1 protein
Niclosamide results in increased ubiquitination of CTNNB1 protein
Niclosamide results in decreased expression of CTNNB1 mRNA
Niclosamide affects the localization of CTNNB1 protein
CTD PMID:19772353 PMID:21531761 PMID:22576131 PMID:24534281 PMID:24552774 More... NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 multiple interactions
increases expression
ISO Niclosamide inhibits the reaction [CTNNB1 protein binds to CTNNBIP1 protein]
Niclosamide results in increased expression of CTNNBIP1 mRNA
CTD PMID:24534281 PMID:36318118 NCBI chr 5:159,961,961...160,010,942
Ensembl chr 5:159,961,928...160,010,939
JBrowse link
G Ctsc cathepsin C decreases expression ISO Niclosamide results in decreased expression of CTSC protein CTD PMID:29480568 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsd cathepsin D decreases expression ISO Niclosamide results in decreased expression of CTSD protein CTD PMID:29480568 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsk cathepsin K multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:26792726 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 decreases expression ISO Niclosamide results in decreased expression of CXCL12 mRNA CTD PMID:36318118 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA] CTD PMID:33632240 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Cyb561 cytochrome b-561 decreases expression ISO Niclosamide results in decreased expression of CYB561 mRNA CTD PMID:36318118 NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Niclosamide results in increased expression of CYCS protein CTD PMID:26703449 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO Niclosamide results in increased activity of CYP1A1 protein CTD PMID:12451431 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression
ISO Niclosamide results in decreased activity of CYP1A2 protein
Niclosamide results in increased expression of CYP1A2 mRNA
CTD PMID:11124226 PMID:28284560 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP27A1 mRNA CTD PMID:36318118 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Niclosamide results in decreased activity of CYP2D6 protein CTD PMID:11124226 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 increases expression ISO Niclosamide results in increased expression of CYP39A1 mRNA CTD PMID:28284560 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Niclosamide results in decreased activity of CYP3A4 protein CTD PMID:11124226 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dact3 dishevelled-binding antagonist of beta-catenin 3 increases expression ISO Niclosamide results in increased expression of DACT3 mRNA CTD PMID:36318118 NCBI chr 1:77,546,900...77,558,631
Ensembl chr 1:77,546,900...77,558,630
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Niclosamide results in increased expression of DBP mRNA CTD PMID:36318118 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent increases expression ISO Niclosamide results in increased expression of DDAH2 mRNA CTD PMID:36318118 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor decreases expression ISO Niclosamide results in decreased expression of DDIAS mRNA CTD PMID:36318118 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Niclosamide results in increased expression of DDIT3 mRNA; Niclosamide results in increased expression of DDIT3 protein
ATF3 protein affects the reaction [Niclosamide results in increased expression of DDIT3 mRNA]
CTD PMID:26917416 PMID:36318118 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Niclosamide results in increased expression of DDIT4 mRNA CTD PMID:36318118 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Niclosamide results in increased expression of DDR1 mRNA CTD PMID:36318118 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 decreases expression ISO Niclosamide results in decreased expression of DECR1 mRNA CTD PMID:22576131 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit decreases expression ISO Niclosamide results in decreased expression of DGCR8 mRNA CTD PMID:36318118 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242
JBrowse link
G Dgkb diacylglycerol kinase, beta increases expression ISO Niclosamide results in increased expression of DGKB mRNA CTD PMID:36318118 NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043
JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Niclosamide results in decreased expression of DHFR mRNA CTD PMID:36318118 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO Niclosamide results in increased expression of DHRS3 mRNA CTD PMID:36318118 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Niclosamide results in decreased expression of DKK1 mRNA CTD PMID:36318118 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Niclosamide results in increased expression of DLG4 mRNA CTD PMID:36318118 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like decreases expression ISO Niclosamide results in decreased expression of DMAC2L mRNA CTD PMID:22576131 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression ISO Niclosamide results in decreased expression of DNAJA1 mRNA CTD PMID:36318118 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 decreases expression ISO Niclosamide results in decreased expression of DNAJA4 mRNA CTD PMID:36318118 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajc22 DnaJ heat shock protein family (Hsp40) member C22 increases expression ISO Niclosamide results in increased expression of DNAJC22 mRNA CTD PMID:36318118 NCBI chr 7:130,257,504...130,262,880
Ensembl chr 7:130,257,851...130,263,230
JBrowse link
G Dnajc9 DnaJ heat shock protein family (Hsp40) member C9 decreases expression ISO Niclosamide results in decreased expression of DNAJC9 mRNA CTD PMID:36318118 NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118
JBrowse link
G Dock5 dedicator of cytokinesis 5 decreases expression ISO Niclosamide results in decreased expression of DOCK5 mRNA CTD PMID:36318118 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
G Dqx1 DEAQ box RNA-dependent ATPase 1 increases expression ISO Niclosamide results in increased expression of DQX1 mRNA CTD PMID:36318118 NCBI chr 4:115,563,497...115,572,598
Ensembl chr 4:115,563,752...115,572,590
JBrowse link
G Drd4 dopamine receptor D4 increases expression ISO Niclosamide results in increased expression of DRD4 mRNA CTD PMID:36318118 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA] CTD PMID:27542212 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Niclosamide results in decreased expression of DTL mRNA CTD PMID:36318118 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Niclosamide results in increased expression of DUSP4 mRNA CTD PMID:36318118 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Niclosamide results in increased expression of DUSP8 mRNA CTD PMID:36318118 NCBI chr 1:197,167,392...197,184,285
Ensembl chr 1:197,169,422...197,182,921
JBrowse link
G Dusp9 dual specificity phosphatase 9 increases expression ISO Niclosamide results in increased expression of DUSP9 mRNA CTD PMID:36318118 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 increases expression ISO Niclosamide results in increased expression of DVL1 mRNA CTD PMID:22576131 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 decreases expression
multiple interactions
ISO
EXP
Niclosamide results in decreased expression of DVL2 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of DVL2 mRNA]]
CTD PMID:19772353 PMID:21531761 PMID:30143678 PMID:32961231 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820
JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression ISO Niclosamide results in increased expression of DVL3 mRNA CTD PMID:22576131 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462
JBrowse link
G Dyrk1b dual specificity tyrosine phosphorylation regulated kinase 1B increases expression ISO Niclosamide results in increased expression of DYRK1B mRNA CTD PMID:36318118 NCBI chr 1:83,479,168...83,497,011
Ensembl chr 1:83,479,147...83,487,169
JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of E2F1 mRNA CTD PMID:29843133 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f2 E2F transcription factor 2 decreases expression ISO Niclosamide results in decreased expression of E2F2 mRNA CTD PMID:36318118 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f7 E2F transcription factor 7 decreases expression ISO Niclosamide results in decreased expression of E2F7 mRNA CTD PMID:36318118 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Niclosamide results in decreased expression of E2F8 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Eaf2 ELL associated factor 2 decreases expression ISO Niclosamide results in decreased expression of EAF2 mRNA CTD PMID:36318118 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ebf1 EBF transcription factor 1 decreases expression ISO Niclosamide results in decreased expression of EBF1 mRNA CTD PMID:27226553 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665
JBrowse link
G Ebf4 EBF family member 4 increases expression ISO Niclosamide results in increased expression of EBF4 mRNA CTD PMID:36318118 NCBI chr 3:117,498,186...117,566,566
Ensembl chr 3:117,498,319...117,566,566
JBrowse link
G Echdc1 ethylmalonyl-CoA decarboxylase 1 decreases expression ISO Niclosamide results in decreased expression of ECHDC1 mRNA CTD PMID:22576131 NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319
JBrowse link
G Echdc2 enoyl CoA hydratase domain containing 2 decreases expression ISO Niclosamide results in decreased expression of ECHDC2 mRNA CTD PMID:36318118 NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 decreases expression ISO Niclosamide results in decreased expression of ECHS1 mRNA CTD PMID:22576131 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Efna1 ephrin A1 increases expression ISO Niclosamide results in increased expression of EFNA1 mRNA CTD PMID:36318118 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866
JBrowse link
G Efna3 ephrin A3 increases expression ISO Niclosamide results in increased expression of EFNA3 mRNA CTD PMID:36318118 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
JBrowse link
G Efnb3 ephrin B3 increases expression ISO Niclosamide results in increased expression of EFNB3 mRNA CTD PMID:36318118 NCBI chr10:54,274,506...54,281,951
Ensembl chr10:54,274,506...54,280,471
JBrowse link
G Egf epidermal growth factor decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of EGF mRNA; Niclosamide results in decreased expression of EGF protein
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein binds to EGFR protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Niclosamide inhibits the reaction [EGF protein binds to EGFR protein]; Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]
CTD PMID:30779072 PMID:38185387 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfr epidermal growth factor receptor decreases expression
decreases phosphorylation
multiple interactions
ISO Niclosamide analog results in decreased expression of EGFR protein; Niclosamide results in decreased expression of EGFR mRNA; Niclosamide results in decreased expression of EGFR protein
Niclosamide results in decreased phosphorylation of EGFR protein
[3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein binds to EGFR protein]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Atrazine co-treated with Niclosamide co-treated with nonachlor co-treated with bisphenol S] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Niclosamide inhibits the reaction [EGF protein binds to EGFR protein]
CTD PMID:28284560 PMID:28426875 PMID:30779072 PMID:38185387 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression
decreases expression
ISO Niclosamide results in increased expression of EGR1 mRNA
Niclosamide results in decreased expression of EGR1 mRNA
CTD PMID:28284560 PMID:36318118 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO Niclosamide results in increased expression of EIF2AK3 mRNA
ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA]; Niclosamide results in increased expression of and results in increased phosphorylation of EIF2AK3 protein
CTD PMID:26917416 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Niclosamide results in increased phosphorylation of EIF2S1 protein CTD PMID:26917416 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 increases expression ISO Niclosamide results in increased expression of EIF4A2 mRNA CTD PMID:36318118 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
decreases phosphorylation
multiple interactions
ISO Niclosamide analog results in decreased expression of EIF4EBP1 protein modified form; Niclosamide results in decreased expression of EIF4EBP1 protein modified form
Niclosamide results in decreased phosphorylation of EIF4EBP1 protein
Niclosamide inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Niclosamide promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
CTD PMID:19771169 PMID:28284560 PMID:30258081 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Elf1 E74 like ETS transcription factor 1 increases expression ISO Niclosamide results in increased expression of ELF1 mRNA CTD PMID:36318118 NCBI chr15:54,890,644...54,986,721
Ensembl chr15:54,865,616...54,986,699
JBrowse link
G Elfn1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 increases expression ISO Niclosamide results in increased expression of ELFN1 mRNA CTD PMID:36318118 NCBI chr12:14,660,049...14,725,709
Ensembl chr12:14,660,083...14,724,580
JBrowse link
G Eml2 EMAP like 2 increases expression ISO Niclosamide results in increased expression of EML2 mRNA CTD PMID:36318118 NCBI chr 1:78,827,595...78,859,342
Ensembl chr 1:78,828,080...78,859,341
JBrowse link
G Endod1 endonuclease domain containing 1 multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA] CTD PMID:27542212 NCBI chr 8:11,209,113...11,238,507
Ensembl chr 8:11,211,110...11,238,892
JBrowse link
G Eng endoglin increases expression ISO Niclosamide results in increased expression of ENG mRNA CTD PMID:36318118 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Eno2 enolase 2 increases expression ISO Niclosamide results in increased expression of ENO2 mRNA CTD PMID:22576131 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eno3 enolase 3 decreases expression ISO Niclosamide results in decreased expression of ENO3 mRNA CTD PMID:22576131 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Niclosamide results in increased expression of EP300 mRNA CTD PMID:22576131 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:36318118 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Epha8 Eph receptor A8 increases expression ISO Niclosamide results in increased expression of EPHA8 mRNA CTD PMID:36318118 NCBI chr 5:149,166,107...149,193,515
Ensembl chr 5:149,166,697...149,193,399
JBrowse link
G Eps8l3 EPS8 like 3 increases expression ISO Niclosamide results in increased expression of EPS8L3 mRNA CTD PMID:28284560 NCBI chr 2:195,514,692...195,528,085
Ensembl chr 2:195,514,692...195,528,085
JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase increases expression ISO Niclosamide results in increased expression of ETHE1 mRNA CTD PMID:36318118 NCBI chr 1:80,184,037...80,199,092
Ensembl chr 1:80,183,894...80,199,052
JBrowse link
G Eva1b eva-1 homolog B increases expression ISO Niclosamide results in increased expression of EVA1B mRNA CTD PMID:36318118 NCBI chr 5:138,427,088...138,429,602
Ensembl chr 5:138,427,151...138,432,433
JBrowse link
G Exo5 exonuclease 5 decreases expression ISO Niclosamide results in decreased expression of EXO5 mRNA CTD PMID:36318118 NCBI chr 5:134,494,440...134,497,757
Ensembl chr 5:134,493,829...134,497,772
JBrowse link
G Exog exo/endonuclease G decreases expression ISO Niclosamide results in decreased expression of EXOG mRNA CTD PMID:36318118 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672
JBrowse link
G F10 coagulation factor X increases expression ISO Niclosamide results in increased expression of F10 mRNA CTD PMID:36318118 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G F12 coagulation factor XII increases expression ISO Niclosamide results in increased expression of F12 mRNA CTD PMID:36318118 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Fam131c family with sequence similarity 131, member C increases expression ISO Niclosamide results in increased expression of FAM131C mRNA CTD PMID:36318118 NCBI chr 5:153,674,459...153,690,791
Ensembl chr 5:153,671,772...153,690,800
JBrowse link
G Fam135b family with sequence similarity 135, member B increases expression ISO Niclosamide results in increased expression of FAM135B mRNA CTD PMID:36318118 NCBI chr 7:103,380,981...103,649,802
Ensembl chr 7:103,386,915...103,649,708
JBrowse link
G Fam13b family with sequence similarity 13, member B decreases expression ISO Niclosamide results in decreased expression of FAM13B mRNA CTD PMID:36318118 NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587
JBrowse link
G Fam221a family with sequence similarity 221, member A increases expression ISO Niclosamide results in increased expression of FAM221A mRNA CTD PMID:36318118 NCBI chr 4:78,337,296...78,358,918
Ensembl chr 4:78,337,296...78,358,909
JBrowse link
G Fam43a family with sequence similarity 43, member A increases expression ISO Niclosamide results in increased expression of FAM43A mRNA CTD PMID:36318118 NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401
JBrowse link
G Fam43b family with sequence similarity 43, member B increases expression ISO Niclosamide results in increased expression of FAM43B mRNA CTD PMID:36318118 NCBI chr 5:150,610,656...150,613,054
Ensembl chr 5:150,611,609...150,612,601
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO Niclosamide results in decreased expression of FAM83D mRNA CTD PMID:28284560 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fancb FA complementation group B decreases expression ISO Niclosamide results in decreased expression of FANCB mRNA CTD PMID:36318118 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO
EXP
Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of BCL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of CXCR5 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL21 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL6 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of PRDM1 mRNA]; Niclosamide affects the reaction [FAS protein mutant form affects the expression of TCF7 protein]; Niclosamide affects the reaction [FAS protein mutant form affects the phosphorylation of STAT3 protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FAS mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FAS mRNA]
CTD PMID:28318631 PMID:33632240 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fastkd3 FAST kinase domains 3 decreases expression ISO Niclosamide results in decreased expression of FASTKD3 mRNA CTD PMID:36318118 NCBI chr 1:34,858,342...34,866,988
Ensembl chr 1:34,858,219...34,866,973
JBrowse link
G Fbxo2 F-box protein 2 increases expression ISO Niclosamide results in increased expression of FBXO2 mRNA CTD PMID:36318118 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
JBrowse link
G Fbxo48 F-box protein 48 increases expression ISO Niclosamide results in increased expression of FBXO48 mRNA CTD PMID:36318118 NCBI chr14:91,380,857...91,382,314
Ensembl chr14:91,380,857...91,382,314
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 increases expression ISO Niclosamide results in increased expression of FCHO1 mRNA CTD PMID:36318118 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
JBrowse link
G Fcrlb Fc receptor-like B increases expression ISO Niclosamide results in increased expression of FCRLB mRNA CTD PMID:36318118 NCBI chr13:83,148,685...83,157,157
Ensembl chr13:83,149,751...83,155,957
JBrowse link
G Fen1 flap structure-specific endonuclease 1 decreases expression ISO Niclosamide results in decreased expression of FEN1 mRNA CTD PMID:36318118 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
JBrowse link
G Fgd1 FYVE, RhoGEF and PH domain containing 1 increases expression ISO Niclosamide results in increased expression of FGD1 mRNA CTD PMID:36318118 NCBI chr  X:20,023,746...20,066,734
Ensembl chr  X:20,023,746...20,066,566
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases expression ISO Niclosamide results in decreased expression of FGF1 mRNA; Niclosamide results in decreased expression of FGF1 protein CTD PMID:25174399 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgf19 fibroblast growth factor 19 increases expression ISO Niclosamide results in increased expression of FGF19 mRNA CTD PMID:36318118 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression ISO Niclosamide results in increased expression of FGFR4 mRNA CTD PMID:36318118 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link
G Fignl1 fidgetin-like 1 decreases expression ISO Niclosamide results in decreased expression of FIGNL1 mRNA CTD PMID:36318118 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression
ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of FKBP5 mRNA
Niclosamide results in decreased expression of FKBP5 mRNA
CTD PMID:28500234 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 decreases expression ISO Niclosamide results in decreased expression of FLRT3 mRNA CTD PMID:36318118 NCBI chr 3:127,994,491...128,008,137
Ensembl chr 3:127,994,226...128,007,841
JBrowse link
G Fmn1 formin 1 increases expression ISO Niclosamide results in increased expression of FMN1 mRNA CTD PMID:36318118 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Niclosamide inhibits the reaction [Doxorubicin results in increased expression of FN1 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]
CTD PMID:28318631 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fndc10 fibronectin type III domain containing 10 increases expression ISO Niclosamide results in increased expression of FNDC10 mRNA CTD PMID:36318118 NCBI chr 5:166,299,587...166,311,477
Ensembl chr 5:166,300,122...166,310,326
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Niclosamide results in increased expression of FNDC4 mRNA CTD PMID:36318118 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of FOS mRNA]
Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]
CTD PMID:26792726 PMID:28824321 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSB mRNA CTD PMID:28284560 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Niclosamide results in increased expression of FOSL1 mRNA CTD PMID:22576131 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxl1 forkhead box L1 increases expression ISO Niclosamide results in increased expression of FOXL1 mRNA CTD PMID:36318118 NCBI chr19:49,197,269...49,200,682
Ensembl chr19:49,197,400...49,198,425
JBrowse link
G Foxm1 forkhead box M1 multiple interactions
decreases expression
ISO Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of FOXM1 protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of FOXM1 protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of FOXM1 protein] CTD PMID:27492973 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO Niclosamide results in increased expression of FOXO4 mRNA CTD PMID:36318118 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Foxo6 forkhead box O6 increases expression ISO Niclosamide results in increased expression of FOXO6 mRNA CTD PMID:36318118 NCBI chr 5:133,856,087...133,876,387
Ensembl chr 5:133,856,072...133,876,573
JBrowse link
G Frat2 FRAT regulator of WNT signaling pathway 2 increases expression ISO Niclosamide results in increased expression of FRAT2 mRNA CTD PMID:36318118 NCBI chr 1:240,654,120...240,656,449
Ensembl chr 1:240,654,137...240,656,517
JBrowse link
G Frzb frizzled-related protein increases expression ISO Niclosamide results in increased expression of FRZB mRNA CTD PMID:36318118 NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
JBrowse link
G Fscn1 fascin actin-bundling protein 1 multiple interactions ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of FSCN1 mRNA] CTD PMID:29733962 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Fstl3 follistatin like 3 increases expression ISO Niclosamide results in increased expression of FSTL3 mRNA CTD PMID:36318118 NCBI chr 7:9,923,574...9,929,223
Ensembl chr 7:9,923,576...9,939,639
JBrowse link
G Fzd1 frizzled class receptor 1 affects localization ISO Niclosamide affects the localization of FZD1 protein CTD PMID:19772353 NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression
increases expression
ISO Niclosamide results in decreased expression of FZD2 mRNA
Niclosamide results in increased expression of FZD2 mRNA
CTD PMID:22576131 PMID:36318118 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Fzd5 frizzled class receptor 5 increases expression ISO Niclosamide results in increased expression of FZD5 mRNA CTD PMID:22576131 NCBI chr 9:66,113,096...66,120,276
Ensembl chr 9:66,113,112...66,121,457
JBrowse link
G Fzd9 frizzled class receptor 9 decreases expression ISO Niclosamide results in decreased expression of FZD9 mRNA CTD PMID:22576131 NCBI chr12:21,427,084...21,429,398
Ensembl chr12:21,427,084...21,429,398
JBrowse link
G G4 G4 protein affects expression ISO Niclosamide affects the expression of C6ORF47 mRNA CTD PMID:36318118 NCBI chr20:3,693,691...3,696,194
Ensembl chr20:3,693,649...3,696,088
JBrowse link
G Gab2 GRB2-associated binding protein 2 increases expression ISO Niclosamide results in increased expression of GAB2 mRNA CTD PMID:36318118 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Niclosamide results in increased expression of GABARAPL1 mRNA CTD PMID:36318118 NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression ISO Niclosamide results in increased expression of GABRA4 mRNA CTD PMID:36318118 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression ISO Niclosamide results in increased expression of GABRB1 mRNA CTD PMID:36318118 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Niclosamide results in increased expression of GADD45B mRNA CTD PMID:36318118 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Garin1a golgi associated RAB2 interactor 1A increases expression ISO Niclosamide results in increased expression of GARIN1A mRNA CTD PMID:36318118 NCBI chr 4:57,880,019...57,890,824
Ensembl chr 4:57,880,019...57,890,820
JBrowse link
G Gata5 GATA binding protein 5 increases expression ISO Niclosamide results in increased expression of GATA5 mRNA CTD PMID:36318118 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751
JBrowse link
G Gcg glucagon multiple interactions EXP Niclosamide inhibits the reaction [GCG protein results in increased abundance of Cyclic AMP]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased expression of CCND1 protein]; Niclosamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]; Niclosamide inhibits the reaction [GCG protein results in increased phosphorylation of CTNNB1 protein] CTD PMID:26964897 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit decreases expression ISO Niclosamide results in decreased expression of GCLM mRNA CTD PMID:36318118 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Niclosamide results in increased expression of GDF15 mRNA CTD PMID:36318118 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdpd5 glycerophosphodiester phosphodiesterase domain containing 5 increases expression ISO Niclosamide results in increased expression of GDPD5 mRNA CTD PMID:36318118 NCBI chr 1:153,679,718...153,761,452
Ensembl chr 1:153,679,718...153,761,446
JBrowse link
G Gdpgp1 GDP-D-glucose phosphorylase 1 decreases expression ISO Niclosamide results in decreased expression of GDPGP1 mRNA CTD PMID:36318118 NCBI chr 1:134,184,119...134,193,281
Ensembl chr 1:134,183,696...134,219,783
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Niclosamide results in decreased expression of GFAP protein CTD PMID:34118929 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gid4 GID complex subunit 4 increases expression ISO Niclosamide results in increased expression of GID4 mRNA CTD PMID:36318118 NCBI chr10:45,221,556...45,247,627
Ensembl chr10:45,245,754...45,247,621
Ensembl chr10:45,245,754...45,247,621
JBrowse link
G Gins1 GINS complex subunit 1 decreases expression ISO Niclosamide results in decreased expression of GINS1 mRNA CTD PMID:36318118 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
JBrowse link
G Gins2 GINS complex subunit 2 decreases expression ISO Niclosamide results in decreased expression of GINS2 mRNA CTD PMID:36318118 NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression ISO Niclosamide results in decreased expression of GINS3 mRNA CTD PMID:36318118 NCBI chr19:9,420,085...9,428,621
Ensembl chr19:9,420,086...9,428,687
JBrowse link
G Gins4 GINS complex subunit 4 decreases expression ISO Niclosamide results in decreased expression of GINS4 mRNA CTD PMID:36318118 NCBI chr16:68,787,572...68,799,938
Ensembl chr16:68,767,339...68,802,273
JBrowse link
G Glb1l3 galactosidase, beta 1-like 3 decreases expression ISO Niclosamide results in decreased expression of GLB1L3 mRNA CTD PMID:36318118 NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904
JBrowse link
G Glis1 GLIS family zinc finger 1 increases expression ISO Niclosamide results in increased expression of GLIS1 mRNA CTD PMID:36318118 NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Niclosamide results in increased expression of GLIS2 mRNA CTD PMID:36318118 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578
JBrowse link
G Gng7 G protein subunit gamma 7 increases expression ISO Niclosamide results in increased expression of GNG7 mRNA CTD PMID:36318118 NCBI chr 7:8,697,458...8,761,239
Ensembl chr 7:8,697,521...8,761,240
JBrowse link
G Golga2 golgin A2 increases expression ISO Niclosamide results in increased expression of GOLGA2 mRNA CTD PMID:36318118 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 decreases expression ISO Niclosamide results in decreased expression of GOSR2 mRNA CTD PMID:36318118 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression ISO Niclosamide results in increased expression of GOT2 mRNA CTD PMID:22576131 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta increases expression ISO Niclosamide results in increased expression of GP1BB mRNA CTD PMID:36318118 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Gpc2 glypican 2 increases expression ISO Niclosamide results in increased expression of GPC2 mRNA CTD PMID:36318118 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208
JBrowse link
G Gpr153 G protein-coupled receptor 153 increases expression ISO Niclosamide results in increased expression of GPR153 mRNA CTD PMID:36318118 NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971
JBrowse link
G Gpr75 G protein-coupled receptor 75 decreases expression ISO Niclosamide results in decreased expression of GPR75 mRNA CTD PMID:36318118 NCBI chr14:104,609,542...104,618,885
Ensembl chr14:104,611,089...104,620,370
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Niclosamide results in increased expression of GPRC5C mRNA CTD PMID:36318118 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
JBrowse link
G Grem2 gremlin 2, DAN family BMP antagonist decreases expression ISO Niclosamide results in decreased expression of GREM2 mRNA CTD PMID:36318118 NCBI chr13:86,778,543...86,871,509
Ensembl chr13:86,778,500...86,871,615
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO Niclosamide results in increased expression of GRIK5 mRNA CTD PMID:36318118 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression ISO Niclosamide results in increased expression of GRIN2D mRNA CTD PMID:36318118 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression ISO Niclosamide results in increased expression of GRIP2 mRNA CTD PMID:36318118 NCBI chr 4:124,271,456...124,356,538
Ensembl chr 4:124,271,456...124,321,268
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
decreases phosphorylation
increases phosphorylation
ISO Niclosamide results in decreased expression of GSK3B mRNA
Niclosamide results in decreased phosphorylation of GSK3B protein
Niclosamide results in increased phosphorylation of GSK3B protein
CTD PMID:22576131 PMID:30143678 PMID:35115509 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gstt2 glutathione S-transferase theta 2 decreases expression ISO Niclosamide results in decreased expression of GSTT2 mRNA CTD PMID:36318118 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 decreases expression
increases expression
ISO Niclosamide results in decreased expression of GTF2H4 mRNA
Niclosamide results in increased expression of GTF2H4 mRNA
CTD PMID:36318118 NCBI chr20:3,071,328...3,076,990
Ensembl chr20:3,071,328...3,076,984
JBrowse link
G Gtse1 G-2 and S-phase expressed 1 decreases expression ISO Niclosamide results in decreased expression of GTSE1 mRNA CTD PMID:28284560 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
JBrowse link
G Gxylt2 glucoside xylosyltransferase 2 increases expression ISO Niclosamide results in increased expression of GXYLT2 mRNA CTD PMID:36318118 NCBI chr 4:133,347,230...133,449,708
Ensembl chr 4:133,347,499...133,449,454
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase decreases expression ISO Niclosamide results in decreased expression of HADH mRNA CTD PMID:22576131 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
increases expression
ISO Niclosamide results in decreased expression of HAMP mRNA
Niclosamide results in increased expression of HAMP mRNA
CTD PMID:25633564 PMID:28284560 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hbp1 HMG-box transcription factor 1 multiple interactions
increases expression
ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]
Niclosamide results in increased expression of HBP1 mRNA
CTD PMID:27542212 PMID:36318118 NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787
JBrowse link
G Hdac5 histone deacetylase 5 increases expression ISO Niclosamide results in increased expression of HDAC5 mRNA CTD PMID:36318118 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Helz2 helicase with zinc finger 2 increases expression ISO Niclosamide results in increased expression of HELZ2 mRNA CTD PMID:36318118 NCBI chr 3:168,338,813...168,353,219
Ensembl chr 3:168,338,813...168,353,159
JBrowse link
G Hes1 hes family bHLH transcription factor 1 decreases expression
multiple interactions
ISO
EXP
Niclosamide results in decreased expression of HES1 protein
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HES1 mRNA]; Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of HES1 mRNA]]
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HES1 mRNA]
CTD PMID:19160421 PMID:28318631 PMID:32961231 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 multiple interactions ISO
EXP
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY1 mRNA]
CTD PMID:27542212 PMID:28318631 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression
EXP
ISO
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HEY2 mRNA]
Niclosamide results in increased expression of HEY2 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Niclosamide results in increased expression of HEY2 mRNA]
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HEY2 mRNA]
CTD PMID:19160421 PMID:28318631 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218
JBrowse link
G Hhipl1 HHIP-like 1 increases expression ISO Niclosamide results in increased expression of HHIPL1 mRNA CTD PMID:36318118 NCBI chr 6:127,219,616...127,243,839
Ensembl chr 6:127,220,014...127,242,564
JBrowse link
G Hid1 HID1 domain containing increases expression ISO Niclosamide results in increased expression of HID1 mRNA CTD PMID:36318118 NCBI chr10:100,589,555...100,610,050
Ensembl chr10:100,589,555...100,610,041
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of HIF1A mRNA; Niclosamide results in decreased expression of HIF1A protein
Niclosamide inhibits the reaction [EGF protein results in increased expression of HIF1A mRNA]; Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD PMID:30779072 PMID:36318118 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 multiple interactions ISO
EXP
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of HIPK2 protein]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 mRNA]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]
HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]]; HIPK2 protein inhibits the reaction [Niclosamide inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Niclosamide inhibits the reaction [TGFB1 protein promotes the reaction [SMAD3 protein binds to HIPK2 promoter]]; Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of HIPK2 protein]
CTD PMID:28318631 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Niclosamide results in increased expression of H2BC21 mRNA CTD PMID:36318118 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642
JBrowse link
G Hivep2 HIVEP zinc finger 2 increases expression ISO Niclosamide results in increased expression of HIVEP2 mRNA CTD PMID:36318118 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993
JBrowse link
G Hk3 hexokinase 3 decreases expression ISO Niclosamide results in decreased expression of HK3 mRNA CTD PMID:36318118 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase increases expression ISO Niclosamide results in increased expression of HMGCL mRNA CTD PMID:36318118 NCBI chr 5:148,178,203...148,192,072
Ensembl chr 5:148,178,252...148,192,068
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Niclosamide results in decreased expression of HMMR mRNA CTD PMID:28284560 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hmx2 H6 family homeobox 2 increases expression ISO Niclosamide results in increased expression of HMX2 mRNA CTD PMID:36318118 NCBI chr 1:186,319,110...186,326,771
Ensembl chr 1:186,319,110...186,326,771
JBrowse link
G Hoga1 4-hydroxy-2-oxoglutarate aldolase 1 increases expression ISO Niclosamide results in increased expression of HOGA1 mRNA CTD PMID:36318118 NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568
JBrowse link
G Homer1 homer scaffold protein 1 decreases expression ISO Niclosamide results in decreased expression of HOMER1 mRNA CTD PMID:36318118 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Homer3 homer scaffold protein 3 increases expression ISO Niclosamide results in increased expression of HOMER3 mRNA CTD PMID:36318118 NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680
JBrowse link
G Hoxa1 homeobox A1 increases expression ISO Niclosamide results in increased expression of HOXA1 CTD PMID:26820057 NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Hr HR, lysine demethylase and nuclear receptor corepressor increases expression ISO Niclosamide results in increased expression of HR mRNA CTD PMID:36318118 NCBI chr15:45,626,835...45,646,313
Ensembl chr15:45,626,835...45,646,313
JBrowse link
G Hrh1 histamine receptor H 1 increases expression ISO Niclosamide results in increased expression of HRH1 mRNA CTD PMID:36318118 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455
JBrowse link
G Hs6st1 heparan sulfate 6-O-sulfotransferase 1 decreases expression ISO Niclosamide results in decreased expression of HS6ST1 mRNA CTD PMID:36318118 NCBI chr 9:38,283,502...38,322,684
Ensembl chr 9:38,282,395...38,322,683
JBrowse link
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 increases expression ISO Niclosamide results in increased expression of HSD17B14 mRNA CTD PMID:36318118 NCBI chr 1:96,029,224...96,039,577
Ensembl chr 1:96,029,284...96,039,883
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression ISO Niclosamide results in increased expression of HSD3B1 mRNA CTD PMID:36318118 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 increases expression ISO Niclosamide results in increased expression of HSD3B2 mRNA CTD PMID:36318118 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Niclosamide results in increased expression of HSPA6 mRNA CTD PMID:36318118 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hspb7 heat shock protein family B (small) member 7 increases expression ISO Niclosamide results in increased expression of HSPB7 mRNA CTD PMID:36318118 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 increases expression ISO Niclosamide results in increased expression of HVCN1 mRNA CTD PMID:36318118 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO
EXP
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of ICAM1 mRNA]
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of ICAM1 mRNA]
CTD PMID:28318631 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Icam5 intercellular adhesion molecule 5 increases expression ISO Niclosamide results in increased expression of ICAM5 mRNA CTD PMID:36318118 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Id1 inhibitor of DNA binding 1 increases expression ISO Niclosamide results in increased expression of ID1 mRNA CTD PMID:36318118 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ier5l immediate early response 5-like increases expression ISO Niclosamide results in increased expression of IER5L mRNA CTD PMID:36318118 NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance ISO IGF1R protein affects the susceptibility to Niclosamide CTD PMID:27497986 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO Niclosamide results in increased expression of IGFBP4 mRNA CTD PMID:36318118 NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects localization ISO Niclosamide affects the localization of IKBKB protein CTD PMID:26116531 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects localization ISO Niclosamide affects the localization of IKBKG protein CTD PMID:26116531 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 increases expression ISO Niclosamide results in increased expression of IKZF2 mRNA CTD PMID:36318118 NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Niclosamide inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA] CTD PMID:26297436 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il17re interleukin 17 receptor E increases expression ISO Niclosamide results in increased expression of IL17RE mRNA CTD PMID:36318118 NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA] CTD PMID:33524445 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il21 interleukin 21 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL21 protein]; Niclosamide inhibits the reaction [resiquimod results in increased expression of IL21 protein] CTD PMID:33632240 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of IL6 protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of IL6 mRNA]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Niclosamide inhibits the reaction [resiquimod results in increased expression of IL6 protein]
Niclosamide inhibits the reaction [IL6 protein results in decreased susceptibility to enzalutamide]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of APPA mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of BIRC5 protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of CCND1 mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of IL12A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of MYC protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of SOCS1A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of TGFB1A mRNA]; Niclosamide inhibits the reaction [IL6 protein results in increased phosphorylation of and results in increased activity of STAT3 protein]
CTD PMID:24561310 PMID:25970160 PMID:26297436 PMID:28318631 PMID:33632240 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Inafm1 InaF-motif containing 1 increases expression ISO Niclosamide results in increased expression of INAFM1 mRNA CTD PMID:36318118 NCBI chr 1:76,976,808...76,978,292 JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 increases expression ISO Niclosamide results in increased expression of INCA1 mRNA CTD PMID:36318118 NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Niclosamide results in increased expression of INHBE mRNA CTD PMID:36318118 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J increases expression ISO Niclosamide results in increased expression of INPP5J mRNA CTD PMID:36318118 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326
JBrowse link
G Insrr insulin receptor-related receptor decreases expression ISO Niclosamide results in decreased expression of INSRR mRNA CTD PMID:36318118 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800
JBrowse link
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 increases expression ISO Niclosamide results in increased expression of IQSEC3 mRNA CTD PMID:36318118 NCBI chr 4:154,610,933...154,707,310
Ensembl chr 4:154,610,934...154,707,310
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Niclosamide results in increased expression of IRAK2 mRNA CTD PMID:36318118 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 increases expression ISO Niclosamide results in increased expression of IRF2BP2 mRNA CTD PMID:36318118 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGAV mRNA] CTD PMID:26792726 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGB3 mRNA]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of ITGB3 mRNA]
CTD PMID:26792726 PMID:28824321 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Niclosamide results in increased expression of JADE2 mRNA CTD PMID:36318118 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984
JBrowse link
G Jak3 Janus kinase 3 increases expression ISO Niclosamide results in increased expression of JAK3 mRNA CTD PMID:36318118 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 increases expression ISO Niclosamide results in increased expression of JAKMIP3 mRNA CTD PMID:36318118 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104
JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Niclosamide results in increased expression of JDP2 mRNA CTD PMID:36318118 NCBI chr 6:105,261,619...105,302,386
Ensembl chr 6:105,261,373...105,301,485
JBrowse link
G Jph3 junctophilin 3 increases expression ISO Niclosamide results in increased expression of JPH3 mRNA CTD PMID:36318118 NCBI chr19:49,793,967...49,855,338
Ensembl chr19:49,793,092...49,855,338
JBrowse link
G Jph4 junctophilin 4 increases expression ISO Niclosamide results in increased expression of JPH4 mRNA CTD PMID:36318118 NCBI chr15:28,579,579...28,588,903
Ensembl chr15:28,571,568...28,587,573
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit affects localization
increases expression
increases phosphorylation
multiple interactions
EXP
ISO
Niclosamide affects the localization of JUN protein
Niclosamide results in increased expression of JUN mRNA
Niclosamide results in increased phosphorylation of JUN protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Niclosamide results in increased phosphorylation of JUN protein]; Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]; JUN protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]
CTD PMID:24750999 PMID:27338550 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kbtbd11 kelch repeat and BTB domain containing 11 increases expression ISO Niclosamide results in increased expression of KBTBD11 mRNA CTD PMID:36318118 NCBI chr16:74,618,291...74,638,010
Ensembl chr16:74,615,792...74,637,736
JBrowse link
G Kcnf1 potassium voltage-gated channel modifier subfamily F member 1 increases expression ISO Niclosamide results in increased expression of KCNF1 mRNA CTD PMID:36318118 NCBI chr 6:39,962,301...39,964,979
Ensembl chr 6:39,962,307...39,964,979
JBrowse link
G Kcnk13 potassium two pore domain channel subfamily K member 13 decreases expression ISO Niclosamide results in decreased expression of KCNK13 mRNA CTD PMID:36318118 NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240
JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 increases expression ISO Niclosamide results in increased expression of KCNN3 mRNA CTD PMID:36318118 NCBI chr 2:174,929,846...175,088,910
Ensembl chr 2:174,936,629...175,081,145
JBrowse link
G Kcnv1 potassium voltage-gated channel modifier subfamily V member 1 decreases expression ISO Niclosamide results in decreased expression of KCNV1 mRNA CTD PMID:36318118 NCBI chr 7:76,260,695...76,269,170
Ensembl chr 7:76,260,695...76,269,170
JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 increases expression ISO Niclosamide results in increased expression of KCTD11 mRNA CTD PMID:36318118 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760
JBrowse link
G Kdelr3 KDEL endoplasmic reticulum protein retention receptor 3 increases expression ISO Niclosamide results in increased expression of KDELR3 mRNA CTD PMID:36318118 NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600
JBrowse link
G Kdm5b lysine demethylase 5B increases expression ISO Niclosamide results in increased expression of KDM5B mRNA CTD PMID:36318118 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kdm6b lysine demethylase 6B increases expression ISO Niclosamide results in increased expression of KDM6B mRNA CTD PMID:36318118 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
G Kdm7a lysine demethylase 7A increases expression ISO Niclosamide results in increased expression of KDM7A mRNA CTD PMID:36318118 NCBI chr 4:67,899,407...67,974,264
Ensembl chr 4:67,904,307...67,966,998
JBrowse link
G Khnyn KH and NYN domain containing increases expression ISO Niclosamide results in increased expression of KHNYN mRNA CTD PMID:36318118 NCBI chr15:29,365,399...29,379,650
Ensembl chr15:29,365,260...29,376,967
JBrowse link
G Kiaa1614 KIAA1614 homolog decreases expression ISO Niclosamide results in decreased expression of KIAA1614 mRNA CTD PMID:36318118 NCBI chr13:67,388,916...67,427,392
Ensembl chr13:67,389,044...67,421,272
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO Niclosamide results in decreased expression of KIF11 mRNA CTD PMID:28284560 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Niclosamide results in decreased expression of KIF20A mRNA CTD PMID:28284560 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Niclosamide results in decreased expression of KIFC1 mRNA CTD PMID:28284560 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Kirrel2 kirre like nephrin family adhesion molecule 2 increases expression ISO Niclosamide results in increased expression of KIRREL2 mRNA CTD PMID:36318118 NCBI chr 1:85,708,793...85,718,670
Ensembl chr 1:85,708,793...85,718,670
JBrowse link
G Kiz kizuna centrosomal protein increases expression ISO Niclosamide results in increased expression of KIZ mRNA CTD PMID:36318118 NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190
JBrowse link
G Klc4 kinesin light chain 4 increases expression ISO Niclosamide results in increased expression of KLC4 mRNA CTD PMID:36318118 NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066
JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Niclosamide results in increased expression of KLF15 mRNA CTD PMID:36318118 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf9 KLF transcription factor 9 increases expression ISO Niclosamide results in increased expression of KLF9 mRNA CTD PMID:36318118 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Klhdc8a kelch domain containing 8A increases expression ISO Niclosamide results in increased expression of KLHDC8A mRNA CTD PMID:36318118 NCBI chr13:43,735,702...43,744,277
Ensembl chr13:43,736,192...43,744,277
JBrowse link
G Klhdc8b kelch domain containing 8B increases expression ISO Niclosamide results in increased expression of KLHDC8B mRNA CTD PMID:36318118 NCBI chr 8:109,141,594...109,146,584
Ensembl chr 8:109,141,594...109,146,918
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Niclosamide results in increased expression of KLHL24 mRNA CTD PMID:36318118 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
JBrowse link
G Klhl30 kelch-like family member 30 increases expression ISO Niclosamide results in increased expression of KLHL30 mRNA CTD PMID:36318118 NCBI chr 9:91,942,475...91,952,756
Ensembl chr 9:91,942,504...91,952,730
JBrowse link
G Klhl34 kelch-like family member 34 decreases expression ISO Niclosamide results in decreased expression of KLHL34 mRNA CTD PMID:36318118 NCBI chr  X:37,151,298...37,154,053
Ensembl chr  X:37,151,592...37,153,529
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of KLK3 mRNA; Niclosamide results in decreased expression of KLK3 protein
[Niclosamide co-treated with bicalutamide] results in decreased expression of KLK3 mRNA; [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]] which results in decreased expression of KLK3 protein; bicalutamide promotes the reaction [Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]]; enzalutamide promotes the reaction [Niclosamide results in decreased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein alternative form binds to KLK3 promoter]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in increased expression of KLK3 protein]; Niclosamide inhibits the reaction [AR protein binds to KLK3 promoter]; Niclosamide inhibits the reaction [Dihydrotestosterone results in increased expression of KLK3 mRNA]
CTD PMID:24740322 PMID:25970160 PMID:28500234 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052
JBrowse link
G Larp6 La ribonucleoprotein 6, translational regulator increases expression ISO Niclosamide results in increased expression of LARP6 mRNA CTD PMID:36318118 NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535
JBrowse link
G Lbh LBH regulator of WNT signaling pathway increases expression ISO Niclosamide results in increased expression of LBH mRNA CTD PMID:36318118 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
JBrowse link
G Lbx2 ladybird homeobox 2 increases expression ISO Niclosamide results in increased expression of LBX2 mRNA CTD PMID:36318118 NCBI chr 4:115,591,974...115,593,859
Ensembl chr 4:115,591,974...115,594,132
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Niclosamide results in increased expression of LCAT mRNA CTD PMID:28284560 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 decreases expression ISO Niclosamide results in decreased expression of LCMT2 mRNA CTD PMID:36318118 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084
JBrowse link
G Lcorl ligand dependent nuclear receptor corepressor-like increases expression ISO Niclosamide results in increased expression of LCORL mRNA CTD PMID:36318118 NCBI chr14:65,271,339...65,407,732
Ensembl chr14:65,271,135...65,404,174
JBrowse link
G Ldha lactate dehydrogenase A increases expression
multiple interactions
decreases expression
ISO Niclosamide results in increased expression of LDHA mRNA
Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of LDHA mRNA]
Niclosamide results in decreased expression of LDHA mRNA
CTD PMID:22576131 PMID:36318118 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
G Leng9 leukocyte receptor cluster member 9 increases expression ISO Niclosamide results in increased expression of LENG9 mRNA CTD PMID:36318118 NCBI chr 1:70,039,099...70,041,559
Ensembl chr 1:70,035,791...70,044,509
JBrowse link
G Lgals3 galectin 3 increases expression ISO Niclosamide results in increased expression of LGALS3 mRNA CTD PMID:36318118 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lgals8 galectin 8 decreases expression ISO Niclosamide results in decreased expression of LGALS8 mRNA CTD PMID:36318118 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764
JBrowse link
G Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase increases expression ISO Niclosamide results in increased expression of LHPP mRNA CTD PMID:36318118 NCBI chr 1:187,403,390...187,494,577
Ensembl chr 1:187,403,433...187,494,578
JBrowse link
G Lhx6 LIM homeobox 6 increases expression ISO Niclosamide results in increased expression of LHX6 mRNA CTD PMID:36318118 NCBI chr 3:19,432,439...19,456,268
Ensembl chr 3:19,433,494...19,456,061
JBrowse link
G Lingo1 leucine rich repeat and Ig domain containing 1 increases expression ISO Niclosamide results in increased expression of LINGO1 mRNA CTD PMID:36318118 NCBI chr 8:57,011,272...57,193,496
Ensembl chr 8:57,010,007...57,196,544
JBrowse link
G Lipg lipase G, endothelial type decreases expression ISO Niclosamide results in decreased expression of LIPG mRNA CTD PMID:36318118 NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
JBrowse link
G Lix1 limb and CNS expressed 1 decreases expression ISO Niclosamide results in decreased expression of LIX1 mRNA CTD PMID:36318118 NCBI chr 1:58,128,961...58,187,554
Ensembl chr 1:58,128,961...58,185,964
JBrowse link
G Lmtk3 lemur tyrosine kinase 3 increases expression ISO Niclosamide results in increased expression of LMTK3 mRNA CTD PMID:36318118 NCBI chr 1:96,261,058...96,280,362
Ensembl chr 1:96,260,977...96,280,672
JBrowse link
G Lonrf1 LON peptidase N-terminal domain and ring finger 1 increases expression ISO Niclosamide results in increased expression of LONRF1 mRNA CTD PMID:36318118 NCBI chr16:55,984,572...56,015,156
Ensembl chr16:55,984,463...56,015,156
JBrowse link
G Loxl3 lysyl oxidase-like 3 increases expression ISO Niclosamide results in increased expression of LOXL3 mRNA CTD PMID:36318118 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466
JBrowse link
G Lpin3 lipin 3 increases expression ISO Niclosamide results in increased expression of LPIN3 mRNA CTD PMID:36318118 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Niclosamide results in increased expression of LRP1 mRNA CTD PMID:36318118 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lrp10 LDL receptor related protein 10 increases expression ISO Niclosamide results in increased expression of LRP10 mRNA CTD PMID:36318118 NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505
JBrowse link
G Lrp5 LDL receptor related protein 5 multiple interactions EXP Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP5 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP5 mRNA]] CTD PMID:32961231 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 decreases expression
multiple interactions
ISO
EXP
Niclosamide analog results in decreased expression of LRP6 protein; Niclosamide results in decreased expression of LRP6 protein
Niclosamide results in decreased expression of and results in decreased phosphorylation of LRP6 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]]
CTD PMID:24552774 PMID:24736023 PMID:28284560 PMID:32961231 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Lrrc2 leucine rich repeat containing 2 increases expression ISO Niclosamide results in increased expression of LRRC2 mRNA CTD PMID:36318118 NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185
JBrowse link
G Lrrc55 leucine rich repeat containing 55 decreases expression ISO Niclosamide results in decreased expression of LRRC55 mRNA CTD PMID:36318118 NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639
JBrowse link
G Lrrc73 leucine rich repeat containing 73 increases expression ISO Niclosamide results in increased expression of LRRC73 mRNA CTD PMID:36318118 NCBI chr 9:14,726,157...14,730,144
Ensembl chr 9:14,726,158...14,729,158
JBrowse link
G Lrrc75b leucine rich repeat containing 75B increases expression ISO Niclosamide results in increased expression of LRRC75B mRNA CTD PMID:36318118 NCBI chr20:13,100,302...13,106,503
Ensembl chr20:13,100,302...13,106,503
JBrowse link
G Lsp1 lymphocyte-specific protein 1 decreases expression ISO Niclosamide results in decreased expression of LSP1 mRNA CTD PMID:36318118 NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 increases expression ISO Niclosamide results in increased expression of LTBP4 mRNA CTD PMID:36318118 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
JBrowse link
G Ly6g5b lymphocyte antigen 6 family member G5B decreases expression ISO Niclosamide results in decreased expression of LY6G5B mRNA CTD PMID:36318118 NCBI chr20:3,705,464...3,707,830
Ensembl chr20:3,706,124...3,707,133
JBrowse link
G Lyrm9 LYR motif containing 9 increases expression ISO Niclosamide results in increased expression of LYRM9 mRNA CTD PMID:36318118 NCBI chr10:63,725,718...63,739,772
Ensembl chr10:63,725,743...63,739,772
JBrowse link
G Macc1 MET transcriptional regulator MACC1 multiple interactions ISO Niclosamide inhibits the reaction [MACC1 protein results in increased expression of S100A4 protein] CTD PMID:36008464 NCBI chr 6:140,352,690...140,430,255
Ensembl chr 6:140,352,755...140,430,255
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Niclosamide results in decreased expression of MAD2L1 mRNA CTD PMID:28284560 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Magix MAGI family member, X-linked increases expression ISO Niclosamide results in increased expression of MAGIX mRNA CTD PMID:36318118 NCBI chr  X:14,824,114...14,832,466
Ensembl chr  X:14,824,188...14,831,045
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Niclosamide results in increased expression of MAP1LC3B protein modified form CTD PMID:30258081 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
ISO Niclosamide results in decreased phosphorylation of MAPK1 protein
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK1 protein]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD PMID:24561310 PMID:26116531 PMID:28426875 PMID:28824321 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK3 protein]; Niclosamide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
Niclosamide results in decreased phosphorylation of MAPK3 protein
CTD PMID:24561310 PMID:26116531 PMID:28426875 PMID:28824321 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK8 protein] CTD PMID:28824321 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of MAPK9 protein] CTD PMID:28824321 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Niclosamide results in increased expression of MAPT mRNA CTD PMID:36318118 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO Niclosamide results in increased expression of MASP1 mRNA CTD PMID:36318118 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G MAST1 microtubule associated serine/threonine kinase 1 increases expression ISO Niclosamide results in increased expression of MAST1 mRNA CTD PMID:36318118 NCBI chr19:23,216,418...23,244,224
Ensembl chr19:23,207,991...23,244,235
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Niclosamide results in decreased expression of MAT2A mRNA CTD PMID:36318118 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Matn1 matrilin 1 increases expression ISO Niclosamide results in increased expression of MATN1 mRNA CTD PMID:36318118 NCBI chr 5:143,117,198...143,127,140
Ensembl chr 5:143,117,504...143,127,059
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 increases expression ISO Niclosamide results in increased expression of MBOAT7 mRNA CTD PMID:36318118 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO Niclosamide results in decreased expression of MCL1 protein CTD PMID:20215516 PMID:26116531 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Niclosamide results in decreased expression of MCM10 mRNA CTD PMID:36318118 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 decreases expression ISO Niclosamide results in decreased expression of MCM2 mRNA; Niclosamide results in decreased expression of MCM2 protein CTD PMID:28284560 PMID:29031202 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Niclosamide results in decreased expression of MCM5 mRNA CTD PMID:36318118 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression ISO Niclosamide results in decreased expression of MCM6 mRNA CTD PMID:36318118 NCBI chr13:39,826,745...39,851,937
Ensembl chr13:39,826,763...39,851,960
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 decreases expression ISO Niclosamide results in decreased expression of MCM7 protein CTD PMID:29031202 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Me3 malic enzyme 3 decreases expression ISO Niclosamide results in decreased expression of ME3 mRNA CTD PMID:36318118 NCBI chr 1:143,534,024...143,735,551
Ensembl chr 1:143,534,139...143,733,132
JBrowse link
G Med31 mediator complex subunit 31 decreases expression ISO Niclosamide results in decreased expression of MED31 mRNA CTD PMID:36318118 NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326
JBrowse link
G Mef2d myocyte enhancer factor 2D increases expression ISO Niclosamide results in increased expression of MEF2D mRNA CTD PMID:36318118 NCBI chr 2:173,606,054...173,635,620
Ensembl chr 2:173,606,490...173,634,457
JBrowse link
G Meis3 Meis homeobox 3 increases expression ISO Niclosamide results in increased expression of MEIS3 mRNA CTD PMID:36318118 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Niclosamide results in increased expression of MESP1 mRNA CTD PMID:36318118 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression EXP Niclosamide results in decreased expression of MET mRNA CTD PMID:27338550 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator increases expression ISO Niclosamide results in increased expression of METRNL mRNA CTD PMID:36318118 NCBI chr10:106,963,880...106,977,875
Ensembl chr10:106,963,880...106,977,869
JBrowse link
G Mgll monoglyceride lipase increases expression ISO Niclosamide results in increased expression of MGLL mRNA CTD PMID:36318118 NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
JBrowse link
G Minar2 membrane integral NOTCH2 associated receptor 2 decreases expression ISO Niclosamide results in decreased expression of MINAR2 mRNA CTD PMID:36318118 NCBI chr18:52,539,714...52,554,465
Ensembl chr18:52,539,917...52,554,461
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Niclosamide results in decreased expression of MKI67 mRNA; Niclosamide results in decreased expression of MKI67 protein CTD PMID:28284560 PMID:35115509 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression ISO Niclosamide results in increased expression of MKNK2 mRNA CTD PMID:36318118 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mme membrane metallo-endopeptidase decreases expression ISO Niclosamide results in decreased expression of MME mRNA; Niclosamide results in decreased expression of MME protein CTD PMID:29480568 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmp11 matrix metallopeptidase 11 increases expression ISO Niclosamide results in increased expression of MMP11 mRNA CTD PMID:36318118 NCBI chr20:12,730,846...12,739,629
Ensembl chr20:12,730,836...12,739,628
JBrowse link
G Mmp15 matrix metallopeptidase 15 increases expression ISO Niclosamide results in increased expression of MMP15 mRNA CTD PMID:36318118 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Niclosamide results in decreased expression of MMP2 mRNA; Niclosamide results in decreased expression of MMP2 protein CTD PMID:29251334 PMID:30143678 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions
decreases expression
EXP
ISO
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of MMP7 mRNA]
Niclosamide results in decreased expression of MMP7 mRNA
Niclosamide inhibits the reaction [Doxorubicin results in increased expression of MMP7 mRNA]
CTD PMID:27338550 PMID:28318631 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of MMP9 mRNA; Niclosamide results in decreased expression of MMP9 protein
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of MMP9 mRNA]
CTD PMID:28824321 PMID:29480568 PMID:30143678 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mrc2 mannose receptor, C type 2 increases expression ISO Niclosamide results in increased expression of MRC2 mRNA CTD PMID:36318118 NCBI chr10:90,261,986...90,323,187
Ensembl chr10:90,261,394...90,322,856
JBrowse link
G Mrm2 mitochondrial rRNA methyltransferase 2 decreases expression ISO Niclosamide results in decreased expression of MRM2 mRNA CTD PMID:36318118 NCBI chr12:14,309,556...14,314,759
Ensembl chr12:14,251,941...14,314,118
JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression ISO Niclosamide results in decreased expression of MRPL30 mRNA CTD PMID:36318118 NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257
JBrowse link
G Msantd7 Myb/SANT DNA binding domain containing 7 decreases expression ISO Niclosamide results in decreased expression of MSANTD7 mRNA CTD PMID:36318118 NCBI chr17:74,728,927...74,735,527
Ensembl chr17:74,728,811...74,736,094
JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 increases expression ISO Niclosamide results in increased expression of MT1E mRNA CTD PMID:28284560 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Niclosamide results in increased expression of MT2A mRNA CTD PMID:28284560 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
increases expression
multiple interactions
ISO Niclosamide analog results in decreased phosphorylation of MTOR protein; Niclosamide results in decreased phosphorylation of MTOR protein
Niclosamide results in increased expression of MTOR mRNA
Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of MTOR protein]; Niclosamide inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]
CTD PMID:19771169 PMID:26643609 PMID:26703449 PMID:28284560 PMID:29843133 More... NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mvp major vault protein increases expression ISO Niclosamide results in increased expression of MVP mRNA CTD PMID:36318118 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein increases expression ISO Niclosamide results in increased expression of MXI1 mRNA CTD PMID:36318118 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression
EXP
ISO
Niclosamide inhibits the reaction [GCG protein results in increased expression of MYC mRNA]
[Niclosamide binds to Polyethyleneimine] which results in increased expression of MYC mRNA; [Niclosamide co-treated with bicalutamide] results in decreased expression of MYC mRNA; [Niclosamide co-treated with bicalutamide] results in decreased expression of MYC protein; enzalutamide promotes the reaction [Niclosamide results in decreased expression of MYC protein]; Niclosamide inhibits the reaction [bicalutamide results in increased expression of MYC protein]; Niclosamide inhibits the reaction [IL6 protein results in increased expression of MYC protein]; Niclosamide inhibits the reaction [TNF protein results in increased expression of MYC mRNA]
Niclosamide results in decreased expression of MYC mRNA; Niclosamide results in decreased expression of MYC protein
CTD PMID:19160421 PMID:20215516 PMID:22576131 PMID:25970160 PMID:25988281 More... NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycl MYCL proto-oncogene, bHLH transcription factor increases expression ISO Niclosamide results in increased expression of MYCL mRNA CTD PMID:36318118 NCBI chr 5:135,274,713...135,281,584
Ensembl chr 5:135,274,748...135,281,582
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases expression ISO Niclosamide results in decreased expression of MYCN mRNA; Niclosamide results in decreased expression of MYCN protein CTD PMID:36318118 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myh3 myosin heavy chain 3 increases expression ISO Niclosamide results in increased expression of MYH3 mRNA CTD PMID:34118929 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
JBrowse link
G Myo18b myosin XVIIIb increases expression ISO Niclosamide results in increased expression of MYO18B mRNA CTD PMID:36318118 NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695
JBrowse link
G Myod1 myogenic differentiation 1 increases expression ISO Niclosamide results in increased expression of MYOD1 mRNA CTD PMID:34118929 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Myog myogenin increases expression ISO Niclosamide results in increased expression of MYOG protein CTD PMID:34118929 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Myom3 myomesin 3 increases expression ISO Niclosamide results in increased expression of MYOM3 mRNA CTD PMID:36318118 NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274
JBrowse link
G Myrf myelin regulatory factor increases expression ISO Niclosamide results in increased expression of MYRF mRNA CTD PMID:36318118 NCBI chr 1:206,854,175...206,886,276
Ensembl chr 1:206,854,175...206,886,157
JBrowse link
G N4bp2l1 NEDD4 binding protein 2-like 1 increases expression ISO Niclosamide results in increased expression of N4BP2L1 mRNA CTD PMID:36318118 NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit increases expression ISO Niclosamide results in increased expression of NAA80 mRNA CTD PMID:36318118 NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563
JBrowse link
G Nat1 N-acetyltransferase 1 decreases expression ISO Niclosamide results in decreased expression of NAT1 mRNA CTD PMID:36318118 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Natd1 N-acetyltransferase domain containing 1 increases expression ISO Niclosamide results in increased expression of NATD1 mRNA CTD PMID:36318118 NCBI chr10:45,580,154...45,590,333 JBrowse link
G Nbr1 NBR1, autophagy cargo receptor increases expression ISO Niclosamide results in increased expression of NBR1 mRNA CTD PMID:36318118 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412
JBrowse link
G Ncoa5 nuclear receptor coactivator 5 decreases expression ISO Niclosamide results in decreased expression of NCOA5 mRNA CTD PMID:36318118 NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553
JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 decreases expression ISO Niclosamide results in decreased expression of NDOR1 mRNA CTD PMID:36318118 NCBI chr 3:8,062,629...8,070,873
Ensembl chr 3:8,062,630...8,070,860
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Niclosamide results in increased expression of NDRG1 mRNA CTD PMID:36318118 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 decreases expression ISO Niclosamide results in decreased expression of NDUFA10 mRNA CTD PMID:22576131 NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560
JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 increases expression ISO Niclosamide results in increased expression of NDUFA4L2 mRNA CTD PMID:22576131 PMID:36318118 NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010
JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 decreases expression ISO Niclosamide results in decreased expression of NDUFA7 mRNA CTD PMID:22576131 NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Ndufa8 NADH:ubiquinone oxidoreductase subunit A8 decreases expression ISO Niclosamide results in decreased expression of NDUFA8 mRNA CTD PMID:22576131 NCBI chr 3:19,386,062...19,402,090
Ensembl chr 3:19,386,065...19,402,071
JBrowse link
G Ndufb10 NADH:ubiquinone oxidoreductase subunit B10 decreases expression ISO Niclosamide results in decreased expression of NDUFB10 mRNA CTD PMID:22576131 NCBI chr10:13,749,273...13,751,434
Ensembl chr10:13,749,275...13,751,442
JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 decreases expression ISO Niclosamide results in decreased expression of NDUFB6 mRNA CTD PMID:22576131 NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 increases expression ISO Niclosamide results in increased expression of NDUFC1 mRNA CTD PMID:22576131 NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874
JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 decreases expression ISO Niclosamide results in decreased expression of NDUFS2 mRNA CTD PMID:22576131 NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression ISO Niclosamide results in decreased expression of NDUFS3 mRNA CTD PMID:22576131 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824
JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 decreases expression ISO Niclosamide results in decreased expression of NDUFS7 mRNA CTD PMID:22576131 NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195
JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 decreases expression ISO Niclosamide results in decreased expression of NDUFS8 mRNA CTD PMID:22576131 NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 increases expression ISO Niclosamide results in increased expression of NDUFV3 mRNA CTD PMID:22576131 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074
JBrowse link
G Nectin3 nectin cell adhesion molecule 3 decreases expression ISO Niclosamide results in decreased expression of NECTIN3 mRNA CTD PMID:36318118 NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]
Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of and affects the localization of NFATC1 protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of NFATC1 mRNA]
CTD PMID:26792726 PMID:28824321 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
JBrowse link
G Nfatc2ip nuclear factor of activated T-cells 2 interacting protein decreases expression ISO Niclosamide results in decreased expression of NFATC2IP mRNA CTD PMID:36318118 NCBI chr 1:180,954,834...180,971,847
Ensembl chr 1:180,955,043...180,971,747
JBrowse link
G Nfix nuclear factor I X increases expression ISO Niclosamide results in increased expression of NFIX mRNA CTD PMID:36318118 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization ISO Niclosamide affects the localization of NFKB1 protein CTD PMID:26116531 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 increases expression ISO Niclosamide results in increased expression of NFKB2 mRNA CTD PMID:36318118 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases phosphorylation
multiple interactions
ISO Niclosamide results in decreased phosphorylation of NFKBIA protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Niclosamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of NFKBIA protein]; Niclosamide inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of NFKBIA protein]
Niclosamide inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Niclosamide inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]
CTD PMID:20215516 PMID:26116531 PMID:27492973 PMID:28824321 PMID:33524445 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbil1 NFKB inhibitor like 1 increases expression ISO Niclosamide results in increased expression of NFKBIL1 mRNA CTD PMID:36318118 NCBI chr20:3,589,974...3,608,348
Ensembl chr20:3,590,642...3,605,616
JBrowse link
G Nkd1 NKD inhibitor of WNT signaling pathway 1 multiple interactions
increases expression
ISO Niclosamide inhibits the reaction [Lithium Chloride results in increased expression of NKD1 mRNA]
Niclosamide results in increased expression of NKD1 mRNA
CTD PMID:22576131 PMID:24534281 NCBI chr19:18,476,344...18,549,380
Ensembl chr19:18,476,344...18,549,380
JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions
decreases expression
ISO [Niclosamide co-treated with bicalutamide] results in decreased expression of NKX3-1 mRNA
Niclosamide results in decreased expression of NKX3-1 mRNA
CTD PMID:28500234 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NLRP3 protein] CTD PMID:33524445 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nmrk1 nicotinamide riboside kinase 1 increases expression ISO Niclosamide results in increased expression of NMRK1 mRNA CTD PMID:36318118 NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
JBrowse link
G Nnat neuronatin decreases expression ISO Niclosamide results in decreased expression of NNAT mRNA CTD PMID:36318118 NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834
JBrowse link
G Nostrin nitric oxide synthase trafficking decreases expression ISO Niclosamide results in decreased expression of NOSTRIN mRNA CTD PMID:36318118 NCBI chr 3:53,904,746...53,970,995
Ensembl chr 3:53,904,827...53,970,988
JBrowse link
G Notch1 notch receptor 1 decreases activity
multiple interactions
ISO
EXP
Niclosamide results in decreased activity of NOTCH1 protein
Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of NOTCH1 mRNA]]
CTD PMID:19160421 PMID:32961231 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase increases expression ISO Niclosamide results in increased expression of NOTUM mRNA CTD PMID:36318118 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315
JBrowse link
G Nova2 NOVA alternative splicing regulator 2 increases expression ISO Niclosamide results in increased expression of NOVA2 mRNA CTD PMID:36318118 NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021
JBrowse link
G Nox1 NADPH oxidase 1 decreases expression ISO Niclosamide results in decreased expression of NOX1 mRNA CTD PMID:36318118 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Npas4 neuronal PAS domain protein 4 increases expression ISO Niclosamide results in increased expression of NPAS4 mRNA CTD PMID:36318118 NCBI chr 1:202,281,260...202,298,681
Ensembl chr 1:202,281,958...202,286,724
JBrowse link
G Npr1 natriuretic peptide receptor 1 increases expression ISO Niclosamide results in increased expression of NPR1 mRNA CTD PMID:36318118 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO Niclosamide results in increased expression of NR1D1 mRNA CTD PMID:36318118 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression ISO Niclosamide results in increased expression of NR1D2 mRNA CTD PMID:36318118 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO Niclosamide binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:31312845 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Niclosamide results in increased expression of NR4A1 mRNA CTD PMID:36318118 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nrxn2 neurexin 2 increases expression ISO Niclosamide results in increased expression of NRXN2 mRNA CTD PMID:36318118 NCBI chr 1:203,726,420...203,842,301
Ensembl chr 1:203,735,753...203,842,297
JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial increases expression ISO Niclosamide results in increased expression of NT5M mRNA CTD PMID:36318118 NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150
JBrowse link
G Ntng2 netrin G2 increases expression ISO Niclosamide results in increased expression of NTNG2 mRNA CTD PMID:36318118 NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890
JBrowse link
G Nudt18 nudix hydrolase 18 increases expression ISO Niclosamide results in increased expression of NUDT18 mRNA CTD PMID:36318118 NCBI chr15:45,650,597...45,653,985
Ensembl chr15:45,650,664...45,653,963
JBrowse link
G Nupr2 nuclear protein 2, transcriptional regulator increases expression ISO Niclosamide results in increased expression of NUPR2 mRNA CTD PMID:36318118 NCBI chr12:26,800,123...26,803,228
Ensembl chr12:26,799,800...26,803,304
JBrowse link
G Nxph1 neurexophilin 1 decreases expression ISO Niclosamide results in decreased expression of NXPH1 mRNA CTD PMID:36318118 NCBI chr 4:36,998,068...37,311,135
Ensembl chr 4:36,997,669...37,311,132
JBrowse link
G Nxph2 neurexophilin 2 decreases expression ISO Niclosamide results in decreased expression of NXPH2 mRNA CTD PMID:36318118 NCBI chr 3:5,986,175...5,988,525
Ensembl chr 3:5,756,621...5,987,008
JBrowse link
G Nxph4 neurexophilin 4 increases expression ISO Niclosamide results in increased expression of NXPH4 mRNA CTD PMID:36318118 NCBI chr 7:63,367,758...63,376,579
Ensembl chr 7:63,367,761...63,376,579
JBrowse link
G Nyap1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 increases expression ISO Niclosamide results in increased expression of NYAP1 mRNA CTD PMID:36318118 NCBI chr12:18,956,192...18,967,624
Ensembl chr12:18,956,268...18,967,543
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Niclosamide results in decreased expression of OAS1 mRNA CTD PMID:36318118 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 increases expression ISO Niclosamide results in increased expression of OAZ3 mRNA CTD PMID:36318118 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
G Oca2 OCA2 melanosomal transmembrane protein increases expression ISO Niclosamide results in increased expression of OCA2 mRNA CTD PMID:36318118 NCBI chr 1:107,116,278...107,446,093
Ensembl chr 1:107,116,278...107,446,074
JBrowse link
G Ocstamp osteoclast stimulatory transmembrane protein multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OCSTAMP mRNA] CTD PMID:28824321 NCBI chr 3:154,131,113...154,141,611
Ensembl chr 3:154,132,328...154,136,991
JBrowse link
G Olr765 olfactory receptor 765 decreases expression ISO Niclosamide results in decreased expression of OR4F17 mRNA CTD PMID:36318118 NCBI chr 3:98,118,744...98,121,011
Ensembl chr 3:98,097,957...98,101,421
Ensembl chr 3:98,097,957...98,101,421
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression ISO Niclosamide results in increased expression of OPCML mRNA CTD PMID:36318118 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620
JBrowse link
G Opn3 opsin 3 increases expression ISO Niclosamide results in increased expression of OPN3 mRNA CTD PMID:36318118 NCBI chr13:87,589,333...87,619,847
Ensembl chr13:87,589,333...87,619,847
JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 increases expression ISO Niclosamide results in increased expression of ORAI3 mRNA CTD PMID:36318118 NCBI chr 1:182,381,196...182,386,055
Ensembl chr 1:182,344,293...182,386,052
JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Niclosamide results in decreased expression of ORC1 mRNA CTD PMID:28284560 PMID:36318118 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G Oscar osteoclast associated Ig-like receptor multiple interactions ISO Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased expression of OSCAR mRNA]
Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of OSCAR mRNA]
CTD PMID:26792726 PMID:28824321 NCBI chr 1:65,607,214...65,615,395
Ensembl chr 1:65,607,410...65,613,758
JBrowse link
G Otud1 OTU deubiquitinase 1 increases expression ISO Niclosamide results in increased expression of OTUD1 mRNA CTD PMID:36318118 NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995
JBrowse link
G Otulinl OTU deubiquitinase with linear linkage specificity like decreases expression ISO Niclosamide results in decreased expression of OTULINL mRNA CTD PMID:36318118 NCBI chr 2:78,405,994...78,433,860
Ensembl chr 2:78,408,593...78,433,838
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 decreases expression ISO Niclosamide results in decreased expression of P2RY6 mRNA CTD PMID:36318118 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808
JBrowse link
G Paip2b poly(A) binding protein interacting protein 2B increases expression ISO Niclosamide results in increased expression of PAIP2B mRNA CTD PMID:36318118 NCBI chr 4:116,292,001...116,323,387
Ensembl chr 4:116,292,020...116,323,379
JBrowse link
G Palm paralemmin increases expression ISO Niclosamide results in increased expression of PALM mRNA CTD PMID:36318118 NCBI chr 7:9,886,634...9,912,389
Ensembl chr 7:9,886,643...9,912,555
JBrowse link
G Pard3b par-3 family cell polarity regulator beta increases expression ISO Niclosamide results in increased expression of PARD3B mRNA CTD PMID:36318118 NCBI chr 9:63,038,435...64,067,178
Ensembl chr 9:63,038,436...64,068,053
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
increases expression
decreases expression
ISO [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased cleavage of PARP1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Niclosamide results in increased cleavage of PARP1 protein]; bicalutamide promotes the reaction [Niclosamide results in increased expression of PARP1 protein modified form]; Hydrogen Peroxide promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]; JUN protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]; TP53 gene mutant form promotes the reaction [Niclosamide results in increased cleavage of PARP1 protein]; WNT7A protein affects the reaction [Niclosamide results in increased cleavage of PARP1 protein]
Niclosamide results in decreased expression of PARP1 protein
CTD PMID:24750999 PMID:25174399 PMID:26917416 PMID:28500234 PMID:30258081 More... NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax7 paired box 7 increases expression ISO Niclosamide results in increased expression of PAX7 mRNA CTD PMID:34118929 NCBI chr 5:151,996,368...152,098,023
Ensembl chr 5:151,999,092...152,097,979
JBrowse link
G Pbx1 PBX homeobox 1 increases expression ISO Niclosamide results in increased expression of PBX1 mRNA CTD PMID:36318118 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pbx2 PBX homeobox 2 increases expression ISO Niclosamide results in increased expression of PBX2 mRNA CTD PMID:36318118 NCBI chr20:4,151,500...4,156,425
Ensembl chr20:4,151,500...4,156,425
JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 increases expression ISO Niclosamide results in increased expression of PBXIP1 mRNA CTD PMID:36318118 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919
JBrowse link
G Pc pyruvate carboxylase increases expression ISO Niclosamide results in increased expression of PC mRNA CTD PMID:22576131 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pcdh19 protocadherin 19 decreases expression ISO Niclosamide results in decreased expression of PCDH19 mRNA CTD PMID:36318118 NCBI chr  X:96,767,686...96,873,477
Ensembl chr  X:96,771,947...96,873,524
JBrowse link
G Pcdh20 protocadherin 20 decreases expression ISO Niclosamide results in decreased expression of PCDH20 mRNA CTD PMID:36318118 NCBI chr15:64,425,534...64,431,790
Ensembl chr15:64,425,534...64,431,790
JBrowse link
G Pcgf1 polycomb group ring finger 1 increases expression ISO Niclosamide results in increased expression of PCGF1 mRNA CTD PMID:36318118 NCBI chr 4:115,576,165...115,587,019
Ensembl chr 4:115,583,867...115,587,008
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Niclosamide results in decreased expression of PCNA mRNA CTD PMID:36318118 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Niclosamide results in increased expression of PDCD4 mRNA CTD PMID:36318118 NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Niclosamide results in increased expression of PDE4B mRNA CTD PMID:36318118 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta increases expression
decreases expression
ISO Niclosamide results in increased expression of PDGFRB mRNA
Niclosamide results in decreased expression of PDGFRB protein
CTD PMID:34118929 PMID:36318118 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PDK1 mRNA] CTD PMID:36318118 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 decreases expression
multiple interactions
ISO Niclosamide results in decreased expression of PDK3 mRNA
Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PDK3 mRNA]
CTD PMID:36318118 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557
JBrowse link
G Pdlim4 PDZ and LIM domain 4 increases expression ISO Niclosamide results in increased expression of PDLIM4 mRNA CTD PMID:36318118 NCBI chr10:38,198,686...38,212,935
Ensembl chr10:38,198,689...38,212,938
JBrowse link
G Pdzd7 PDZ domain containing 7 increases expression ISO Niclosamide results in increased expression of PDZD7 mRNA CTD PMID:36318118 NCBI chr 1:243,888,295...243,907,778
Ensembl chr 1:243,888,281...243,906,839
JBrowse link
G Percc1 proline and glutamate rich with coiled coil 1 increases expression ISO Niclosamide results in increased expression of PERCC1 mRNA CTD PMID:36318118 NCBI chr10:14,187,858...14,190,634
Ensembl chr10:14,188,216...14,189,040
Ensembl chr10:14,188,216...14,189,040
JBrowse link
G Pfkm phosphofructokinase, muscle decreases expression ISO Niclosamide results in decreased expression of PFKM mRNA CTD PMID:22576131 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of PGK1 mRNA] CTD PMID:36318118 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Pgr progesterone receptor decreases expression ISO Niclosamide results in decreased expression of PGR mRNA CTD PMID:36318118 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phf24 PHD finger protein 24 increases expression ISO Niclosamide results in increased expression of PHF24 mRNA CTD PMID:36318118 NCBI chr 5:57,143,428...57,171,054
Ensembl chr 5:57,142,632...57,168,497
JBrowse link
G Phka2 phosphorylase kinase regulatory subunit alpha 2 decreases expression ISO Niclosamide results in decreased expression of PHKA2 mRNA CTD PMID:36318118 NCBI chr  X:34,170,959...34,293,498
Ensembl chr  X:34,171,323...34,293,466
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 increases expression ISO Niclosamide results in increased expression of PHLDA1 mRNA CTD PMID:28284560 NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
JBrowse link
G Phldb3 pleckstrin homology-like domain, family B, member 3 increases expression ISO Niclosamide results in increased expression of PHLDB3 mRNA CTD PMID:36318118 NCBI chr 1:80,201,083...80,219,541
Ensembl chr 1:80,201,578...80,219,534
JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein increases expression ISO Niclosamide results in increased expression of PHYHIP mRNA CTD PMID:36318118 NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
JBrowse link
G Pi15 peptidase inhibitor 15 decreases expression ISO Niclosamide results in decreased expression of PI15 mRNA CTD PMID:36318118 NCBI chr 5:1,395,094...1,423,213
Ensembl chr 5:1,395,094...1,423,213
JBrowse link
G Pigw phosphatidylinositol glycan anchor biosynthesis, class W decreases expression ISO Niclosamide results in decreased expression of PIGW mRNA CTD PMID:36318118 NCBI chr10:69,746,996...69,782,656
Ensembl chr10:69,748,789...69,790,475
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha increases expression
multiple interactions
ISO Niclosamide results in increased expression of PIK3CA mRNA
Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CCNG2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CSGALNACT1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of CXCL8 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HBP1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in decreased expression of HEY1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of CCNE2 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of DSCC1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of ENDOD1 mRNA]; Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA]
CTD PMID:27542212 PMID:29843133 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 increases expression ISO Niclosamide results in increased expression of PIK3IP1 mRNA CTD PMID:36318118 NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Niclosamide results in increased expression of PIM1 mRNA CTD PMID:36318118 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Niclosamide results in increased expression of PKM mRNA CTD PMID:22576131 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
JBrowse link
G Pla2g4c phospholipase A2 group IVC increases expression ISO Niclosamide results in increased expression of PLA2G4C mRNA CTD PMID:36318118 NCBI chr 1:74,237,714...74,275,757
Ensembl chr 1:74,236,211...74,274,656
JBrowse link
G Plec plectin increases expression ISO Niclosamide results in increased expression of PLEC mRNA CTD PMID:36318118 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467
JBrowse link
G Plekha2 pleckstrin homology domain containing A2 increases expression ISO Niclosamide results in increased expression of PLEKHA2 mRNA CTD PMID:36318118 NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395
JBrowse link
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 increases expression ISO Niclosamide results in increased expression of PLEKHG4 mRNA CTD PMID:36318118 NCBI chr19:33,251,788...33,266,490
Ensembl chr19:33,249,706...33,266,357
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO Niclosamide results in increased expression of PNRC1 mRNA CTD PMID:36318118 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161
JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO Niclosamide results in increased expression of POLD4 mRNA CTD PMID:36318118 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401
JBrowse link
G Pou3f1 POU class 3 homeobox 1 increases expression ISO Niclosamide results in increased expression of POU3F1 mRNA CTD PMID:36318118 NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases phosphorylation ISO Niclosamide results in decreased phosphorylation of POU5F1 protein CTD PMID:23333246 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO Niclosamide results in increased expression of PPARD mRNA CTD PMID:22576131 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Niclosamide results in increased expression of PPARG mRNA CTD PMID:36318118 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 decreases expression ISO Niclosamide results in decreased expression of PPEF2 mRNA CTD PMID:36318118 NCBI chr14:15,797,414...15,831,620
Ensembl chr14:15,797,435...15,831,491
JBrowse link
G Ppfia3 PTPRF interacting protein alpha 3 increases expression ISO Niclosamide results in increased expression of PPFIA3 mRNA CTD PMID:36318118 NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798
JBrowse link
G Ppil6 peptidylprolyl isomerase like 6 increases expression ISO Niclosamide results in increased expression of PPIL6 mRNA CTD PMID:36318118 NCBI chr20:44,989,509...45,017,833
Ensembl chr20:44,988,943...45,018,340
JBrowse link
G Ppp1r12b protein phosphatase 1, regulatory subunit 12B increases expression ISO Niclosamide results in increased expression of PPP1R12B mRNA CTD PMID:36318118 NCBI chr13:46,199,418...46,397,108
Ensembl chr13:46,201,251...46,397,108
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Niclosamide results in increased expression of PPP1R15A mRNA CTD PMID:36318118 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression ISO Niclosamide results in decreased expression of PPP1R3B mRNA CTD PMID:36318118 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression ISO Niclosamide results in decreased expression of PPP2CB mRNA CTD PMID:22576131 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression ISO Niclosamide results in increased expression of PPP2R1A mRNA CTD PMID:22576131 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta multiple interactions ISO Niclosamide inhibits the reaction [PIK3CA protein modified form results in increased expression of PPP2R1B mRNA] CTD PMID:27542212 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO Niclosamide results in decreased expression of PPP2R2B mRNA CTD PMID:22576131 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma decreases expression ISO Niclosamide results in decreased expression of PPP2R2C mRNA CTD PMID:22576131 NCBI chr14:73,846,547...73,931,489
Ensembl chr14:73,846,547...73,931,864
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO Niclosamide affects the reaction [FAS protein mutant form affects the expression of PRDM1 mRNA] CTD PMID:33632240 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Prkcd protein kinase C, delta increases expression ISO Niclosamide results in increased expression of PRKCD mRNA CTD PMID:36318118 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkcq protein kinase C, theta increases expression ISO Niclosamide results in increased expression of PRKCQ mRNA CTD PMID:22576131 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Prpf8 pre-mRNA processing factor 8 decreases expression ISO Niclosamide results in decreased expression of PRPF8 mRNA CTD PMID:36318118 NCBI chr10:60,331,494...60,354,606
Ensembl chr10:60,331,494...60,354,606
JBrowse link
G Prr29 proline rich 29 decreases expression ISO Niclosamide results in decreased expression of PRR29 mRNA CTD PMID:36318118 NCBI chr10:91,305,820...91,320,661
Ensembl chr10:91,305,723...91,310,439
JBrowse link
G Prr36 proline rich 36 increases expression ISO Niclosamide results in increased expression of PRR36 mRNA CTD PMID:36318118 NCBI chr12:2,560,533...2,567,766
Ensembl chr12:2,560,536...2,567,742
JBrowse link
G Psen2 presenilin 2 decreases expression ISO Niclosamide results in decreased expression of PSEN2 mRNA CTD PMID:36318118 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psmc3ip PSMC3 interacting protein decreases expression ISO Niclosamide results in decreased expression of PSMC3IP mRNA CTD PMID:36318118 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Niclosamide results in increased expression of PTEN mRNA CTD PMID:29843133 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO Niclosamide results in decreased expression of PTGER4 mRNA CTD PMID:36318118 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptges prostaglandin E synthase increases expression ISO Niclosamide results in increased expression of PTGES mRNA CTD PMID:36318118 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases expression ISO Niclosamide results in increased expression of PTK2B mRNA CTD PMID:36318118 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression ISO Niclosamide results in decreased expression of PTPRG mRNA CTD PMID:36318118 NCBI chr15:12,871,706...13,552,186
Ensembl chr15:12,871,721...13,554,094
JBrowse link
G Ptprh protein tyrosine phosphatase, receptor type, H increases expression ISO Niclosamide results in increased expression of PTPRH mRNA CTD PMID:36318118 NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077
JBrowse link
G Ptprt protein tyrosine phosphatase, receptor type, T decreases expression ISO Niclosamide results in decreased expression of PTPRT mRNA CTD PMID:36318118 NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124
JBrowse link
G R3hdm2 R3H domain containing 2 increases expression ISO Niclosamide results in increased expression of R3HDM2 mRNA CTD PMID:36318118 NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540
JBrowse link
G Rab26 RAB26, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB26 mRNA CTD PMID:36318118 NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030
JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB3A mRNA CTD PMID:36318118 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336
JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 increases expression ISO Niclosamide results in increased expression of RAB3IL1 mRNA CTD PMID:36318118 NCBI chr 1:206,646,168...206,682,718
Ensembl chr 1:206,646,155...206,679,972
JBrowse link
G Rab7b Rab7b, member RAS oncogene family increases expression ISO Niclosamide results in increased expression of RAB7B mRNA CTD PMID:36318118 NCBI chr13:43,121,168...43,147,581
Ensembl chr13:43,121,226...43,147,581
JBrowse link
G Rac2 Rac family small GTPase 2 increases expression ISO Niclosamide results in increased expression of RAC2 mRNA CTD PMID:36318118 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
JBrowse link
G Rad54l RAD54 like increases expression ISO Niclosamide results in increased expression of RAD54L mRNA CTD PMID:28284560 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases phosphorylation
decreases expression
ISO Niclosamide analog results in decreased phosphorylation of RAF1 protein
Niclosamide analog results in decreased expression of RAF1 protein; Niclosamide results in decreased expression of RAF1 protein
CTD PMID:28284560 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rasa4 RAS p21 protein activator 4 increases expression ISO Niclosamide results in increased expression of RASA4B mRNA CTD PMID:36318118 NCBI chr12:20,552,805...20,580,177
Ensembl chr12:20,552,806...20,580,147
JBrowse link
G Rassf10 Ras association domain family member 10 decreases expression ISO Niclosamide results in decreased expression of RASSF10 mRNA CTD PMID:36318118 NCBI chr 1:167,058,277...167,063,591
Ensembl chr 1:167,058,099...167,063,572
JBrowse link
G Rbm45 RNA binding motif protein 45 decreases expression ISO Niclosamide results in decreased expression of RBM45 mRNA CTD PMID:36318118 NCBI chr 3:61,305,973...61,320,950
Ensembl chr 3:61,305,924...61,320,952
JBrowse link
G Rcn3 reticulocalbin 3 increases expression ISO Niclosamide results in increased expression of RCN3 mRNA CTD PMID:36318118 NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725
JBrowse link
G Rcor2 REST corepressor 2 increases expression ISO Niclosamide results in increased expression of RCOR2 mRNA CTD PMID:36318118 NCBI chr 1:204,453,403...204,461,403
Ensembl chr 1:204,454,360...204,460,838
JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO Niclosamide results in increased expression of REEP6 mRNA CTD PMID:36318118 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
ISO
EXP
Niclosamide affects the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; Niclosamide inhibits the reaction [[Adenosine Triphosphate co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of and results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [[CSF1 protein co-treated with TNFSF11 protein] results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of RELA protein modified form]
Niclosamide results in decreased expression of RELA protein
Imatinib Mesylate promotes the reaction [Niclosamide results in decreased expression of RELA protein]; Niclosamide inhibits the reaction [[Lapatinib results in decreased susceptibility to Lapatinib] which results in increased phosphorylation of RELA protein]; Niclosamide inhibits the reaction [TNF protein affects the localization of RELA protein]; Niclosamide inhibits the reaction [TNF protein results in increased activity of RELA protein]; Niclosamide inhibits the reaction [WNT3A protein affects the localization of RELA protein]; Niclosamide promotes the reaction [Imatinib Mesylate results in decreased expression of RELA protein]; Niclosamide results in decreased phosphorylation of and affects the localization of RELA protein
Niclosamide inhibits the reaction [TGFB1 protein results in increased expression of RELA protein modified form]
CTD PMID:20215516 PMID:26116531 PMID:26643609 PMID:27492973 PMID:28318631 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Niclosamide results in increased expression of RELB mRNA CTD PMID:36318118 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Rep15 RAB15 effector protein decreases expression ISO Niclosamide results in decreased expression of REP15 mRNA CTD PMID:36318118 NCBI chr 4:179,951,935...179,953,008
Ensembl chr 4:179,951,935...179,953,008
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a decreases expression ISO Niclosamide results in decreased expression of RGMA mRNA CTD PMID:36318118 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918
JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases expression ISO Niclosamide results in increased expression of RGS10 mRNA CTD PMID:36318118 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697
JBrowse link
G Rgs13 regulator of G-protein signaling 13 decreases expression ISO Niclosamide results in decreased expression of RGS13 mRNA CTD PMID:36318118 NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648
JBrowse link
G Rgs14 regulator of G-protein signaling 14 increases expression ISO Niclosamide results in increased expression of RGS14 mRNA CTD PMID:36318118 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104
JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression ISO Niclosamide results in decreased expression of RGS8 mRNA CTD PMID:36318118 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807
JBrowse link
G Rhobtb1 Rho-related BTB domain containing 1 increases expression ISO Niclosamide results in increased expression of RHOBTB1 mRNA CTD PMID:36318118 NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012
JBrowse link
G Rhof ras homolog family member F, filopodia associated multiple interactions ISO Niclosamide inhibits the reaction [Adenosine Triphosphate results in increased expression of RHOF mRNA] CTD PMID:29733962 NCBI chr12:33,422,375...33,446,689
Ensembl chr12:33,431,280...33,446,703
JBrowse link
G Rilpl1 Rab interacting lysosomal protein-like 1 increases expression ISO Niclosamide results in increased expression of RILPL1 mRNA CTD PMID:36318118 NCBI chr12:32,071,870...32,109,687
Ensembl chr12:32,071,693...32,109,938
JBrowse link
G Rin1 Ras and Rab interactor 1 increases expression ISO Niclosamide results in increased expression of RIN1 mRNA CTD PMID:36318118 NCBI chr 1:202,355,729...202,362,731
Ensembl chr 1:202,355,890...202,362,729
JBrowse link
G Ripor3 RIPOR family member 3 increases expression ISO Niclosamide results in increased expression of FAM65C mRNA CTD PMID:28284560 NCBI chr 3:156,687,253...156,760,524
Ensembl chr 3:156,687,517...156,715,061
JBrowse link
G Rnf122 ring finger protein 122 increases expression ISO Niclosamide results in increased expression of RNF122 mRNA CTD PMID:36318118 NCBI chr16:61,009,879...61,027,429
Ensembl chr16:61,009,879...61,027,448
JBrowse link
G Rnf215 ring finger protein 215 increases expression ISO Niclosamide results in increased expression of RNF215 mRNA CTD PMID:36318118 NCBI chr14:79,006,659...79,013,091
Ensembl chr14:79,006,688...79,013,091
JBrowse link
G Rnf227 ring finger protein 227 increases expression ISO Niclosamide results in increased expression of RNF227 mRNA CTD PMID:36318118 NCBI chr10:54,061,054...54,063,015
Ensembl chr10:54,059,947...54,063,010
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO Niclosamide results in decreased expression of ROCK1 mRNA; Niclosamide results in decreased expression of ROCK1 protein CTD PMID:29251334 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G Rps6 ribosomal protein S6 affects phosphorylation ISO Niclosamide affects the phosphorylation of RPS6 protein CTD PMID:27542212 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6ka5 ribosomal protein S6 kinase A5 increases expression ISO Niclosamide results in increased expression of RPS6KA5 mRNA CTD PMID:36318118 NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Niclosamide results in decreased phosphorylation of RPS6KB1 protein CTD PMID:27542212 PMID:30258081 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Niclosamide results in decreased expression of RRM2 mRNA CTD PMID:28284560 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Rsl1 regulator of sex limited protein 1 decreases expression ISO Niclosamide results in decreased expression of ZNF66 mRNA CTD PMID:36318118 NCBI chr 2:84,739,694...84,763,617
Ensembl chr 2:84,718,530...84,762,596
JBrowse link
G Rsph4a radial spoke head component 4A decreases expression ISO Niclosamide results in decreased expression of RSPH4A mRNA CTD PMID:36318118 NCBI chr20:30,764,409...30,780,574
Ensembl chr20:30,764,409...30,780,574
JBrowse link
G Rtn4r reticulon 4 receptor increases expression ISO Niclosamide results in increased expression of RTN4R mRNA CTD PMID:36318118 NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 increases expression ISO Niclosamide results in increased expression of RTN4RL1 mRNA CTD PMID:36318118 NCBI chr10:60,043,246...60,116