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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression |
EXP |
benzophenone results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Anapc11 |
anaphase promoting complex subunit 11 |
decreases expression |
EXP |
benzophenone results in decreased expression of ANAPC11 mRNA |
CTD |
PMID:22584684 |
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NCBI chr10:105,875,209...105,886,307
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G |
Ar |
androgen receptor |
affects binding |
EXP |
benzophenone binds to AR protein |
CTD |
PMID:14565775 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Ccnb1 |
cyclin B1 |
increases expression |
EXP |
benzophenone results in increased expression of CCNB1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cdk1 |
cyclin-dependent kinase 1 |
increases expression |
EXP |
benzophenone results in increased expression of CDK1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression |
EXP |
benzophenone results in increased expression of CYP2B1; benzophenone results in increased expression of CYP2B1 mRNA |
CTD |
PMID:14613717 PMID:22584684 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
increases expression |
EXP |
benzophenone results in increased expression of CYP2B2 mRNA |
CTD |
PMID:14613717 |
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NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
increases expression |
EXP |
benzophenone results in increased expression of CYP2C11 mRNA |
CTD |
PMID:14613717 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
increases expression |
EXP |
benzophenone results in increased expression of CYP3A23-3A1 mRNA |
CTD |
PMID:14613717 |
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NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
benzophenone binds to and results in increased activity of ESR1 protein |
CTD |
PMID:16079615 PMID:27633901 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding |
ISO |
benzophenone binds to and results in increased activity of ESR2 protein benzophenone binds to ESR2 protein |
CTD |
PMID:12224631 PMID:16079615 PMID:27633901 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
benzophenone results in increased expression of FOS mRNA; benzophenone results in increased expression of FOS protein |
CTD |
PMID:24308608 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases activity |
ISO |
benzophenone results in decreased activity of HSD3B1 protein |
CTD |
PMID:37217011 |
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NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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G |
Mir200a |
microRNA 200a |
increases expression |
EXP |
benzophenone results in increased expression of MIR200A mRNA |
CTD |
PMID:22584684 |
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NCBI chr 5:166,648,494...166,648,582
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G |
Mir200b |
microRNA 200b |
increases expression |
EXP |
benzophenone results in increased expression of MIR200B mRNA |
CTD |
PMID:22584684 |
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NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
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G |
Mir221 |
microRNA 221 |
decreases expression |
EXP |
benzophenone results in decreased expression of MIR221 mRNA |
CTD |
PMID:22584684 |
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NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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G |
Mir429 |
microRNA 429 |
increases expression |
EXP |
benzophenone results in increased expression of MIR429 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
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G |
Mir96 |
microRNA 96 |
increases expression |
EXP |
benzophenone results in increased expression of MIR96 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
EXP |
benzophenone binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:14613717 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
increases activity |
ISO |
benzophenone results in increased activity of NR1I3 protein |
CTD |
PMID:28927721 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nusap1 |
nucleolar and spindle associated protein 1 |
increases expression |
EXP |
benzophenone results in increased expression of NUSAP1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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G |
Smad3 |
SMAD family member 3 |
decreases phosphorylation multiple interactions |
ISO |
benzophenone results in decreased phosphorylation of SMAD3 protein fulvestrant inhibits the reaction [benzophenone results in decreased phosphorylation of SMAD3 protein] |
CTD |
PMID:24308608 |
|
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Steap3 |
STEAP3 metalloreductase |
decreases expression |
EXP |
benzophenone results in decreased expression of STEAP3 mRNA |
CTD |
PMID:22584684 |
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NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519
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G |
Stmn1 |
stathmin 1 |
increases expression |
EXP |
benzophenone results in increased expression of STMN1 mRNA |
CTD |
PMID:22584684 |
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NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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G |
Tpo |
thyroid peroxidase |
decreases activity |
ISO |
benzophenone results in decreased activity of TPO protein |
CTD |
PMID:21809831 |
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NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
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G |
Txnl4b |
thioredoxin-like 4B |
increases expression |
EXP |
benzophenone results in increased expression of TXNL4B mRNA |
CTD |
PMID:22584684 |
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NCBI chr19:37,530,157...37,539,827
Ensembl chr19:37,530,152...37,538,521
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G |
A1bg |
alpha-1-B glycoprotein |
decreases expression |
EXP |
Fenofibrate results in decreased expression of A1BG protein |
CTD |
PMID:20118634 |
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NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097
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G |
Aadac |
arylacetamide deacetylase |
increases expression |
ISO |
Fenofibrate results in increased expression of AADAC mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 2:144,163,436...144,186,086
Ensembl chr 2:144,135,319...144,174,734
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G |
Aars1 |
alanyl-tRNA synthetase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of AARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCA1 mRNA; Fenofibrate results in increased expression of ABCA1 protein |
CTD |
PMID:19201410 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions decreases expression decreases activity |
ISO EXP |
Fenofibrate inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Fenofibrate results in decreased expression of ABCB11 mRNA Fenofibrate results in decreased activity of ABCB11 protein |
CTD |
PMID:20829430 PMID:23956101 PMID:24014644 PMID:27765674 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine] |
CTD |
PMID:16316932 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCB4 mRNA |
CTD |
PMID:17118139 PMID:19118567 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcb6 |
ATP binding cassette subfamily B member 6 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ABCB6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924
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G |
Abcb9 |
ATP binding cassette subfamily B member 9 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCB9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCC2 mRNA |
CTD |
PMID:27765674 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ABCC3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCC4 mRNA |
CTD |
PMID:27765674 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of ABCD3 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCG1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCG5 mRNA |
CTD |
PMID:27765674 |
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NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
increases expression |
EXP |
Fenofibrate results in increased expression of ABCG8 mRNA |
CTD |
PMID:27765674 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Abhd4 |
abhydrolase domain containing 4, N-acyl phospholipase B |
increases expression |
EXP |
Fenofibrate results in increased expression of ABHD4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:27,697,384...27,716,013
Ensembl chr15:27,704,113...27,716,966
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G |
Abi3bp |
ABI family member 3 binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ABI3BP mRNA |
CTD |
PMID:25572481 |
|
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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G |
Acaa1a |
acetyl-CoA acyltransferase 1A |
increases expression multiple interactions affects expression |
ISO EXP |
Fenofibrate results in increased expression of ACAA1A mRNA Fenofibrate results in increased expression of ACAA1 mRNA Fenofibrate results in increased expression of ACAA1 mRNA; Fenofibrate results in increased expression of ACAA1A mRNA Fenofibrate promotes the reaction [Pyrazinamide results in increased expression of ACAA1 mRNA]; Pyrazinamide promotes the reaction [Fenofibrate results in increased expression of ACAA1 mRNA] Fenofibrate affects the expression of ACAA1A mRNA |
CTD |
PMID:11798191 PMID:20801182 PMID:24752549 PMID:27071702 PMID:32741897 |
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NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
affects expression increases expression |
EXP ISO |
Fenofibrate affects the expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA Fenofibrate results in increased expression of ACAA2 mRNA; Fenofibrate results in increased expression of ACAA2 protein |
CTD |
PMID:20118634 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions decreases expression increases expression |
ISO EXP |
NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ACACA mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of ACACA protein modified form]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of ACACA protein] Fenofibrate results in decreased expression of ACACA protein |
CTD |
PMID:23063693 PMID:24752549 PMID:32730863 PMID:38216941 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
multiple interactions increases expression |
ISO |
NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA] |
CTD |
PMID:17118139 PMID:23063693 |
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NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
increases expression |
ISO |
Fenofibrate results in increased expression of ACADL mRNA |
CTD |
PMID:17690133 |
|
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ACADM mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA] |
CTD |
PMID:11798191 PMID:17690133 PMID:19124612 PMID:24752549 PMID:25572481 PMID:33408297 More...
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acads |
acyl-CoA dehydrogenase short chain |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of ACADS mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of and results in decreased activity of ACADS protein] |
CTD |
PMID:26989860 |
|
NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ACADVL mRNA |
CTD |
PMID:17118139 PMID:24752549 PMID:27665778 |
|
NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACAT1 mRNA Fenofibrate results in increased expression of ACAT1 mRNA |
CTD |
PMID:18253720 PMID:24752549 |
|
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Acly |
ATP citrate lyase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ACLY mRNA PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA] |
CTD |
PMID:23063693 |
|
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Aco1 |
aconitase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACO1 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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G |
Aco2 |
aconitase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACO2 mRNA |
CTD |
PMID:24752549 |
|
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ACOT1 mRNA |
CTD |
PMID:11798191 PMID:17690133 PMID:27665778 PMID:32741897 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression multiple interactions increases expression |
EXP |
Fenofibrate affects the expression of ACOT2 mRNA Fenofibrate results in increased expression of and results in increased activity of ACOT2 protein Fenofibrate results in increased expression of ACOT2 mRNA |
CTD |
PMID:16595124 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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G |
Acot3 |
acyl-CoA thioesterase 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACOT3 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427 Ensembl chr 6:103,682,596...103,688,427
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G |
Acot4 |
acyl-CoA thioesterase 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACOT4 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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G |
Acot7 |
acyl-CoA thioesterase 7 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACOT7 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
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G |
Acox1 |
acyl-CoA oxidase 1 |
affects expression multiple interactions increases expression |
EXP ISO |
Fenofibrate affects the expression of ACOX1 mRNA [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of ACOX1 protein; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ACOX1 protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of ACOX1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein] Fenofibrate results in increased expression of ACOX1 mRNA; Fenofibrate results in increased expression of ACOX1 protein Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ACOX1 mRNA |
CTD |
PMID:16707586 PMID:17118139 PMID:17690133 PMID:18253720 PMID:18775883 PMID:19395589 PMID:20801182 PMID:22301950 PMID:23063693 PMID:24534255 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25572481 PMID:28871336 PMID:30611848 PMID:32741897 PMID:39442682 More...
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
increases expression affects expression decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of ACSL1 mRNA; Fenofibrate results in increased expression of ACSL1 protein Fenofibrate affects the expression of ACSL1 mRNA Fenofibrate results in decreased expression of ACSL1 protein PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein] PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein] |
CTD |
PMID:10600944 PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25596134 PMID:32741897 More...
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACSL3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL4 mRNA |
CTD |
PMID:17118139 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of ACSL5 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
increases expression |
EXP |
Fenofibrate results in increased expression of ACSL6 mRNA |
CTD |
PMID:16595124 |
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NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
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Acss2 |
acyl-CoA synthetase short-chain family member 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ACSS2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein] Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA] |
CTD |
PMID:28871336 PMID:32613381 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Adam22 |
ADAM metallopeptidase domain 22 |
increases expression |
EXP |
Fenofibrate results in increased expression of ADAM22 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
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Adcy1 |
adenylate cyclase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADCY1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:81,911,240...82,020,594
Ensembl chr14:81,911,099...82,028,969
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Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADH1C mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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Adh4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ADH4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ADIPOQ protein [candesartan co-treated with Fenofibrate] results in increased expression of ADIPOQ protein; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of ADIPOQ protein] |
CTD |
PMID:16443859 PMID:24735863 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adipor2 |
adiponectin receptor 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ADIPOR2 mRNA |
CTD |
PMID:16306350 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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Agrn |
agrin |
decreases expression |
EXP |
Fenofibrate results in decreased expression of AGRN mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
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Agt |
angiotensinogen |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:31016362 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Agxt2 |
alanine-glyoxylate aminotransferase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AGXT2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
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Ahr |
aryl hydrocarbon receptor |
affects activity multiple interactions |
ISO EXP |
Fenofibrate affects the activity of AHR protein Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA]; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of VEGFA protein]] |
CTD |
PMID:25596134 PMID:31016362 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aifm2 |
AIF family member 2 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of AIFM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:29,654,283...29,679,239
Ensembl chr20:29,652,927...29,679,236
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Aig1 |
androgen-induced 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of AIG1 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084
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Ak4 |
adenylate kinase 4 |
affects expression |
EXP |
Fenofibrate affects the expression of AK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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Akr1b10 |
aldo-keto reductase family 1 member B10 |
multiple interactions decreases activity |
ISO |
Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; Fenofibrate inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde] Fenofibrate results in decreased activity of AKR1B10 protein; Fenofibrate results in decreased activity of AKR1B10 protein mutant form |
CTD |
PMID:18325492 PMID:19028477 |
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NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
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Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
ISO |
Fenofibrate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Alb |
albumin |
multiple interactions |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of VCAM1 mRNA]; PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form] Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ALB mRNA] |
CTD |
PMID:20580385 PMID:37076581 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a2 |
aldehyde dehydrogenase 1 family, member A2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
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Aldh6a1 |
aldehyde dehydrogenase 6 family, member A1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALDH6A1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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Aldoa |
aldolase, fructose-bisphosphate A |
increases expression |
EXP |
Fenofibrate results in increased expression of ALDOA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
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Alox12 |
arachidonate 12-lipoxygenase, 12S type |
increases expression |
ISO |
Fenofibrate results in increased expression of ALOX12 mRNA |
CTD |
PMID:12759900 |
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NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
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Alpk2 |
alpha-kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ALPK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258
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Alpl |
alkaline phosphatase, biomineralization associated |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ALPL mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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Anapc11 |
anaphase promoting complex subunit 11 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr10:105,875,209...105,886,307
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Angptl4 |
angiopoietin-like 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ankra2 |
ankyrin repeat family A member 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ANKRA2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730
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Ankrd1 |
ankyrin repeat domain 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ANKRD1 protein APOA2 protein alternative form affects the reaction [Fenofibrate results in increased expression of ANKRD1 protein] |
CTD |
PMID:39442682 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Anxa3 |
annexin A3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ANXA3 protein |
CTD |
PMID:20118634 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of APEX1 mRNA Fenofibrate results in increased expression of APEX1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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Apoa1 |
apolipoprotein A1 |
decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of APOA1 mRNA; Fenofibrate results in decreased expression of APOA1 protein Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA] Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]] [Fenofibrate co-treated with Pyrazinamide] results in increased expression of APOA1 mRNA |
CTD |
PMID:7983038 PMID:19201410 PMID:19445040 PMID:27071702 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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Apoa2 |
apolipoprotein A2 |
multiple interactions |
ISO |
APOA2 protein alternative form affects the reaction [Fenofibrate results in increased expression of ANKRD1 protein] |
CTD |
PMID:39442682 |
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NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
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Apoa4 |
apolipoprotein A4 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of APOA4 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apob |
apolipoprotein B |
decreases expression |
ISO |
Fenofibrate results in decreased expression of APOB protein |
CTD |
PMID:21411093 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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Apoc3 |
apolipoprotein C3 |
affects expression decreases expression |
EXP ISO |
Fenofibrate affects the expression of APOC3 mRNA Fenofibrate results in decreased expression of APOC3 mRNA; Fenofibrate results in decreased expression of APOC3 protein |
CTD |
PMID:8847480 PMID:10799317 PMID:20801182 PMID:24752549 |
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NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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App |
amyloid beta precursor protein |
multiple interactions |
ISO |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Aqp3 |
aquaporin 3 (Gill blood group) |
increases expression |
EXP |
Fenofibrate results in increased expression of AQP3 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
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Aqp7 |
aquaporin 7 |
increases expression |
EXP |
Fenofibrate results in increased expression of AQP7 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
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Aqp9 |
aquaporin 9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of AQP9 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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Arfgef2 |
ARF guanine nucleotide exchange factor 2 |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of ARFGEF2 mRNA Fenofibrate results in decreased expression of ARFGEF2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:155,547,504...155,633,652
Ensembl chr 3:155,547,538...155,630,856
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Arhgef10 |
Rho guanine nucleotide exchange factor 10 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ARHGEF10 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173
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Arih1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ARIH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
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Arl1 |
ARF like GTPase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ARL1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898
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G |
Asb6 |
ankyrin repeat and SOCS box-containing 6 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA Fenofibrate results in increased expression of ASB6 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:14,110,628...14,115,274
Ensembl chr 3:14,110,628...14,115,242
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of ASNS mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Ate1 |
arginyltransferase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATE1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 1:184,961,548...185,081,112
Ensembl chr 1:184,963,562...185,080,908
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of ATF3 mRNA Fenofibrate results in increased expression of ATF3 mRNA |
CTD |
PMID:18978307 PMID:25596134 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atf4 |
activating transcription factor 4 |
affects activity multiple interactions |
ISO EXP |
Fenofibrate affects the activity of ATF4 protein Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF4 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 mRNA]; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of ATF6 protein] |
CTD |
PMID:38216941 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg12 |
autophagy related 12 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATG12 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atg7 |
autophagy related 7 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ATG7 mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of ATG7 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA] |
CTD |
PMID:21318169 PMID:36905866 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Atosa |
atos homolog A |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ATOSA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ATP2A2 protein |
CTD |
PMID:20118634 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp2b4 |
ATPase plasma membrane Ca2+ transporting 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ATP2B4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BAX protein] |
CTD |
PMID:26989860 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcar3 |
BCAR3 adaptor protein, NSP family member |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BCAR3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
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G |
Bcat1 |
branched chain amino acid transaminase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
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G |
Bcat2 |
branched chain amino acid transaminase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of BCAT2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007
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G |
Bckdk |
branched chain ketoacid dehydrogenase kinase |
decreases activity |
EXP |
Fenofibrate results in decreased activity of BCKDK protein |
CTD |
PMID:19819289 |
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NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of BCL2 mRNA Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of BCL2 protein] |
CTD |
PMID:15843896 PMID:26989860 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL2A1 mRNA |
CTD |
PMID:20520642 |
|
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:20520642 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Bcl3 |
BCL3, transcription coactivator |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BCL3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
Bcr |
BCR activator of RhoGEF and GTPase |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of BCR mRNA |
CTD |
PMID:18253720 |
|
NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BDH1 protein |
CTD |
PMID:20118634 |
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NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of BECN1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
decreases expression |
ISO EXP |
Fenofibrate results in decreased expression of BHLHE40 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of BIRC3 mRNA |
CTD |
PMID:20520642 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Bmf |
Bcl2 modifying factor |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of BMF mRNA Fenofibrate results in decreased expression of BMF mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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G |
Bnip3 |
BCL2 interacting protein 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of BNIP3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Brap |
BRCA1 associated protein |
affects expression multiple interactions |
ISO |
Fenofibrate affects the expression of BRAP mRNA PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr12:34,874,533...34,901,030
Ensembl chr12:34,874,533...34,901,030
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G |
Brcc3 |
BRCA1/BRCA2-containing complex subunit 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of BRCC3 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
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G |
Brd2 |
bromodomain containing 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of BRD2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
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G |
Btg2 |
BTG anti-proliferation factor 2 |
affects expression |
EXP |
Fenofibrate affects the expression of BTG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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G |
C1h19orf12 |
similar to human chromosome 19 open reading frame 12 |
increases expression |
ISO |
Fenofibrate results in increased expression of C19ORF12 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:90,873,578...90,887,205
Ensembl chr 1:90,873,549...90,886,208
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G |
C9 |
complement C9 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of C9 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338
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G |
Cacna2d3 |
calcium voltage-gated channel auxiliary subunit alpha2delta 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of CACNA2D3 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
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G |
Calm1 |
calmodulin 1 |
affects expression |
EXP |
Fenofibrate affects the expression of CALM1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Canx |
calnexin |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of CANX mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Car9 |
carbonic anhydrase 9 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA]; Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of CA9 protein] |
CTD |
PMID:34520103 |
|
NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions decreases expression |
ISO EXP |
Fenofibrate results in increased cleavage of CASP3 protein [Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [ACADS protein affects the cleavage of CASP3 protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of CASP3 protein] [ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased activity of CASP3 protein] Fenofibrate inhibits the reaction [Cyclophosphamide results in increased cleavage of CASP3 protein] |
CTD |
PMID:20520642 PMID:26989860 PMID:29134746 PMID:32730863 PMID:36988379 PMID:38278497 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of CASP4 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cat |
catalase |
multiple interactions increases activity increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CAT mRNA Fenofibrate results in increased activity of CAT protein Fenofibrate results in increased expression of CAT mRNA Fenofibrate inhibits the reaction [Cyclophosphamide results in decreased activity of CAT protein] |
CTD |
PMID:17264098 PMID:18253720 PMID:38278497 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CAV1 mRNA |
CTD |
PMID:15314095 |
|
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cblb |
Cbl proto-oncogene B |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of CBLB mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839
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G |
Ccdc34 |
coiled-coil domain containing 34 |
increases expression |
EXP |
Fenofibrate results in increased expression of CCDC34 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 3:96,553,074...96,588,310
Ensembl chr 3:96,552,992...96,588,146
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G |
Ccdc90b |
coiled-coil domain containing 90B |
increases expression |
EXP |
Fenofibrate results in increased expression of CCDC90B mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCL13 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Fenofibrate inhibits the reaction [Glucose results in increased secretion of CCL2 protein] Fenofibrate results in decreased expression of CCL2 mRNA; Fenofibrate results in decreased expression of CCL2 protein Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] |
CTD |
PMID:15968640 PMID:16306350 PMID:16600694 PMID:18356826 PMID:19132243 PMID:32613381 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of CCL5 protein]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of CCL5 protein] |
CTD |
PMID:12126966 PMID:12586603 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
decreases expression multiple interactions increases expression |
ISO |
Fenofibrate results in decreased expression of CCN1 mRNA [Galactose co-treated with Fenofibrate] results in increased expression of CCN1 protein Fenofibrate results in increased expression of CCN1 protein |
CTD |
PMID:25572481 PMID:39442682 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCN2 protein |
CTD |
PMID:39442682 |
|
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CCNA1 protein |
CTD |
PMID:39442682 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Ccnd1 |
cyclin D1 |
decreases expression increases expression multiple interactions |
ISO EXP |
Fenofibrate results in decreased expression of CCND1 mRNA; Fenofibrate results in decreased expression of CCND1 protein Fenofibrate results in increased expression of CCND1 protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein] Fenofibrate results in increased expression of CCND1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CCND1 mRNA |
CTD |
PMID:16569247 PMID:17264098 PMID:18253720 PMID:18978307 PMID:20520642 PMID:29134746 PMID:39442682 More...
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnf |
cyclin F |
increases expression |
EXP |
Fenofibrate results in increased expression of CCNF mRNA |
CTD |
PMID:32741897 |
|
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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G |
Ccng2 |
cyclin G2 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of CCNG2 mRNA Fenofibrate results in increased expression of CCNG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830
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G |
Ccnt1 |
cyclin T1 |
multiple interactions |
EXP |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] |
CTD |
PMID:20828602 |
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NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
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G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
Fenofibrate results in increased expression of CD14 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd36 |
CD36 molecule |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of CD36 mRNA Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA] |
CTD |
PMID:16707586 PMID:17118139 PMID:25572481 PMID:32613381 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd40 |
CD40 molecule |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CD40 mRNA |
CTD |
PMID:20520642 |
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NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
multiple interactions decreases expression |
ISO |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CD40LG protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CD40LG protein] |
CTD |
PMID:16443859 |
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NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cdc25a |
cell division cycle 25A |
increases expression |
EXP |
Fenofibrate results in increased expression of CDC25A mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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G |
Cdk20 |
cyclin-dependent kinase 20 |
increases expression |
ISO |
Fenofibrate results in increased expression of CDK20 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
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G |
Cdk9 |
cyclin-dependent kinase 9 |
multiple interactions |
EXP |
Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] |
CTD |
PMID:20828602 |
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NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions decreases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1A mRNA Fenofibrate results in decreased expression of CDKN1A mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions decreases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; Estradiol inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein] |
CTD |
PMID:18253720 PMID:29134746 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cep128 |
centrosomal protein 128 |
increases expression |
EXP |
Fenofibrate results in increased expression of CEP128 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713
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G |
Cers5 |
ceramide synthase 5 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CERS5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947
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G |
Ces1d |
carboxylesterase 1D |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Chek1 |
checkpoint kinase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of CHEK1 mRNA |
CTD |
PMID:17264098 |
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NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
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G |
Chek2 |
checkpoint kinase 2 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chid1 |
chitinase domain containing 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of CHID1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:196,594,357...196,629,700
Ensembl chr 1:196,587,509...196,629,606
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G |
Chrna2 |
cholinergic receptor nicotinic alpha 2 subunit |
increases expression |
EXP |
Fenofibrate results in increased expression of CHRNA2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr15:40,342,317...40,358,601
Ensembl chr15:40,342,317...40,358,601
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G |
Chst8 |
carbohydrate sulfotransferase 8 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CHST8 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
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G |
Cish |
cytokine inducible SH2-containing protein |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of CISH mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
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G |
Cmbl |
carboxymethylenebutenolidase homolog |
increases expression |
EXP |
Fenofibrate results in increased expression of CMBL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
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G |
Cnot4 |
CCR4-NOT transcription complex, subunit 4 |
multiple interactions increases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:63,712,770...63,814,355
Ensembl chr 4:63,712,770...63,814,360
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]] Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL1A1 mRNA]]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL1A1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]] |
CTD |
PMID:19593819 PMID:28871336 PMID:31016362 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [AHR protein affects the reaction [AGT protein results in increased expression of COL3A1 mRNA]]; Fenofibrate inhibits the reaction [Zoledronic Acid results in increased expression of COL3A1 mRNA] |
CTD |
PMID:28871336 PMID:31016362 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a1 |
collagen type IV alpha 1 chain |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA] |
CTD |
PMID:28871336 |
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NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Colq |
collagen like tail subunit of asymmetric acetylcholinesterase |
increases expression |
EXP |
Fenofibrate results in increased expression of COLQ mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107
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G |
Coq7 |
coenzyme Q7, hydroxylase |
increases expression |
EXP |
Fenofibrate results in increased expression of COQ7 mRNA |
CTD |
PMID:16595124 |
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NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
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G |
Cox6b2 |
cytochrome c oxidase subunit 6B2 |
increases expression |
ISO |
Fenofibrate results in increased expression of COX6B2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:69,094,009...69,095,312
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of CPT1A mRNA Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of CPT1A protein]; Fenofibrate promotes the reaction [Fatty Acids, Nonesterified results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA] |
CTD |
PMID:16595124 PMID:17070643 PMID:17118139 PMID:19124612 PMID:24534255 PMID:24735863 PMID:25572481 PMID:27665778 PMID:28871336 PMID:30611848 PMID:32613381 PMID:32741897 More...
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt1b |
carnitine palmitoyltransferase 1B |
affects expression increases expression multiple interactions |
EXP |
Fenofibrate affects the expression of CPT1B mRNA Fenofibrate results in increased expression of CPT1B mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of CPT1B mRNA] |
CTD |
PMID:16595124 PMID:19395589 PMID:20801182 PMID:27071702 PMID:32741897 |
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NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
decreases expression multiple interactions increases expression |
EXP ISO |
Fenofibrate results in decreased expression of CPT2 protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA Fenofibrate results in increased expression of CPT2 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA] |
CTD |
PMID:16595124 PMID:16707586 PMID:19395589 PMID:20118634 PMID:24534255 PMID:25572481 PMID:27665778 PMID:28871336 PMID:32741897 More...
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NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crat |
carnitine O-acetyltransferase |
increases expression increases activity multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of CRAT mRNA Fenofibrate results in increased activity of CRAT protein [Fenofibrate co-treated with Diethylnitrosamine] results in increased activity of CRAT protein; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CRAT mRNA |
CTD |
PMID:11798191 PMID:17264098 PMID:18253720 PMID:27665778 PMID:32741897 |
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NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
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G |
Creb3l3 |
cAMP responsive element binding protein 3-like 3 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of CREB3L3 mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048
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G |
Crot |
carnitine O-octanoyltransferase |
increases expression |
EXP |
Fenofibrate results in increased expression of CROT mRNA |
CTD |
PMID:32741897 |
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NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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G |
Crp |
C-reactive protein |
multiple interactions decreases expression |
ISO |
candesartan promotes the reaction [Fenofibrate results in decreased expression of CRP protein]; Fenofibrate promotes the reaction [candesartan results in decreased expression of CRP protein] |
CTD |
PMID:16123850 PMID:16443859 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Csf1r |
colony stimulating factor 1 receptor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CSF1R mRNA |
CTD |
PMID:16707586 |
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NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CSF2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Cth |
cystathionine gamma-lyase |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of CTH mRNA Fenofibrate results in decreased expression of CTH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctsc |
cathepsin C |
decreases expression |
EXP |
Fenofibrate results in decreased expression of CTSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 mRNA]; Fenofibrate inhibits the reaction [Glucose results in increased expression of CX3CL1 protein] |
CTD |
PMID:19132243 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of CYCS protein] |
CTD |
PMID:32730863 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyld |
CYLD lysine 63 deubiquitinase |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of CYLD mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA] |
CTD |
PMID:21318169 |
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NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression decreases activity |
EXP ISO |
Fenofibrate results in increased expression of CYP1A1 mRNA Fenofibrate results in decreased activity of CYP1A1 protein |
CTD |
PMID:19118567 PMID:33814510 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions affects expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA Fenofibrate affects the expression of CYP1A2 mRNA |
CTD |
PMID:18253720 PMID:20801182 PMID:25596134 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
decreases activity |
ISO |
Fenofibrate results in decreased activity of CYP1B1 protein |
CTD |
PMID:33814510 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2a3 |
cytochrome P450, family 2, subfamily a, polypeptide 3 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2A3 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP2B1 mRNA |
CTD |
PMID:19118567 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b15 |
cytochrome P450, family 2, subfamily b, polypeptide 15 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP2B15 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2B10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP2C19 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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G |
Cyp2c7 |
cytochrome P450, family 2, subfamily c, polypeptide 7 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2C7 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
decreases activity affects expression increases expression |
ISO |
Fenofibrate results in decreased activity of CYP2C8 protein Fenofibrate affects the expression of CYP2C8 protein Fenofibrate results in increased expression of CYP2C8 mRNA |
CTD |
PMID:15601807 PMID:25572481 PMID:29960002 |
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G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP2E1 mRNA |
CTD |
PMID:19118567 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
affects expression |
ISO |
Fenofibrate affects the expression of CYP2J2 protein |
CTD |
PMID:29960002 |
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NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A23-3A1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP3A13 mRNA |
CTD |
PMID:18253720 |
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NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects expression increases expression multiple interactions |
EXP ISO |
Fenofibrate affects the expression of CYP4A1 mRNA Fenofibrate results in increased expression of CYP4A22 mRNA Fenofibrate results in increased expression of CYP4A1 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of CYP4A1 mRNA |
CTD |
PMID:17264098 PMID:18775883 PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 More...
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4a2 |
cytochrome P450, family 4, subfamily a, polypeptide 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP4A2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
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G |
Cyp4a3 |
cytochrome P450, family 4, subfamily a, polypeptide 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of CYP4A3 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463
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G |
Cyp4a8 |
cytochrome P450, family 4, subfamily a, polypeptide 8 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4A8 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
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G |
Cyp4b1 |
cytochrome P450, family 4, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348
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G |
Cyp4x1 |
cytochrome P450, family 4, subfamily x, polypeptide 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of CYP4X1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions decreases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA Fenofibrate results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:14685799 PMID:18253720 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA Fenofibrate results in increased expression of CYP8B1 mRNA |
CTD |
PMID:18253720 PMID:32741897 |
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NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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G |
Dact2 |
dishevelled-binding antagonist of beta-catenin 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of DACT2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr 1:55,181,023...55,191,026
Ensembl chr 1:55,181,024...55,191,096
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Fenofibrate results in increased expression of DBI mRNA |
CTD |
PMID:17118139 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Dcun1d1 |
defective in cullin neddylation 1 domain containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of DCUN1D1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of DDIT3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
decreases expression increases expression |
ISO EXP |
Fenofibrate results in decreased expression of DDIT4 mRNA Fenofibrate results in increased expression of DDIT4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Ddx24 |
DEAD-box helicase 24 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of DDX24 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:122,564,767...122,582,032
Ensembl chr 6:122,564,767...122,581,927
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G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
increases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of DECR1 mRNA Fenofibrate results in increased expression of DECR1 mRNA; Fenofibrate results in increased expression of DECR1 protein Fenofibrate affects the expression of DECR1 mRNA |
CTD |
PMID:11798191 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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G |
Decr2 |
2,4-dienoyl-CoA reductase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of DECR2 mRNA |
CTD |
PMID:27665778 |
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NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479
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G |
Dhx37 |
DEAH-box helicase 37 |
increases expression |
ISO |
Fenofibrate results in increased expression of DHX37 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:31,194,782...31,214,890
Ensembl chr12:31,194,859...31,216,802
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G |
Dmd |
dystrophin |
decreases expression |
ISO |
Fenofibrate results in decreased expression of DMD mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
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G |
Dnaja2 |
DnaJ heat shock protein family (Hsp40) member A2 |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA Fenofibrate results in increased expression of DNAJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA] |
CTD |
PMID:18253720 PMID:21318169 |
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NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
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G |
Dnaja3 |
DnaJ heat shock protein family (Hsp40) member A3 |
increases expression |
ISO |
Fenofibrate results in increased expression of DNAJA3 mRNA |
CTD |
PMID:21318169 |
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NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJB1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of DNAJB4 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
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G |
Dnajb6 |
DnaJ heat shock protein family (Hsp40) member B6 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJB6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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Dnajc14 |
DnaJ heat shock protein family (Hsp40) member C14 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC14 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 7:1,233,856...1,247,349
Ensembl chr 7:1,235,162...1,248,645
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Dnajc19 |
DnaJ heat shock protein family (Hsp40) member C19 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC19 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 2:116,923,272...116,945,312
Ensembl chr 2:116,923,272...116,945,264
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Dnajc2 |
DnaJ heat shock protein family (Hsp40) member C2 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA Fenofibrate results in increased expression of DNAJC2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431
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Dnajc27 |
DnaJ heat shock protein family (Hsp40) member C27 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of RBJ mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449
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Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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Dnajc5 |
DnaJ heat shock protein family (Hsp40) member C5 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of DNAJC5 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:168,621,905...168,656,570
Ensembl chr 3:168,621,969...168,655,935
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Dnajc5b |
DnaJ heat shock protein family (Hsp40) member C5 beta |
increases expression |
EXP |
Fenofibrate results in increased expression of DNAJC5B mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:101,973,726...102,066,275
Ensembl chr 2:101,973,793...102,066,275
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Dnm1l |
dynamin 1-like |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of DNM1L protein] |
CTD |
PMID:32730863 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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Dnmbp |
dynamin binding protein |
decreases expression |
EXP |
Fenofibrate results in decreased expression of DNMBP mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604
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Dusp5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of DUSP5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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Ech1 |
enoyl-CoA hydratase 1 |
affects expression increases expression |
EXP ISO |
Fenofibrate affects the expression of ECH1 mRNA Fenofibrate results in increased expression of ECH1 mRNA; Fenofibrate results in increased expression of ECH1 protein |
CTD |
PMID:11798191 PMID:17118139 PMID:20118634 PMID:20801182 PMID:27665778 PMID:32741897 More...
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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Echs1 |
enoyl-CoA hydratase, short chain 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ECHS1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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Eci1 |
enoyl-CoA delta isomerase 1 |
increases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of ECI1 mRNA Fenofibrate affects the expression of ECI1 mRNA |
CTD |
PMID:11798191 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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Eci2 |
enoyl-CoA delta isomerase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of ECI2 mRNA |
CTD |
PMID:16707586 |
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NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
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Edn1 |
endothelin 1 |
multiple interactions |
EXP ISO |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA] |
CTD |
PMID:22198280 PMID:31016362 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Egfr |
epidermal growth factor receptor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of EGFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of EHHADH mRNA Fenofibrate affects the expression of EHHADH mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:20801182 PMID:27665778 PMID:32741897 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Eif1 |
eukaryotic translation initiation factor 1 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of EIF1 mRNA Fenofibrate results in increased expression of EIF1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 Ensembl chr 5:85,246,764...85,427,327
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Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Dietary Fats results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:38216941 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Eif2s2 |
eukaryotic translation initiation factor 2 subunit beta |
affects expression |
EXP |
Fenofibrate affects the expression of EIF2S2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432
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Eif3c |
eukaryotic translation initiation factor 3, subunit C |
increases expression |
EXP |
Fenofibrate results in increased expression of EIF3C mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493
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Elk4 |
ETS transcription factor ELK4 |
increases expression |
ISO |
Fenofibrate results in increased expression of ELK4 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:43,451,130...43,475,035
Ensembl chr13:43,435,843...43,475,035
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Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA Fenofibrate results in increased expression of ELOVL6 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA] |
CTD |
PMID:23063693 PMID:24534255 PMID:27665778 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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Enc1 |
ectodermal-neural cortex 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of ENC1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
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Eno1 |
enolase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of ENO1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 Ensembl chr 3:160,719,951...160,731,336
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Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ENPP2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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Entpd7 |
ectonucleoside triphosphate diphosphohydrolase 7 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ENTPD7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447
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Ep400 |
E1A binding protein p400 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of EP400 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:45,891,886...46,002,523
Ensembl chr12:45,891,916...45,998,861
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Ephx2 |
epoxide hydrolase 2 |
affects expression increases expression |
EXP ISO |
Fenofibrate affects the expression of EPHX2 mRNA Fenofibrate results in increased expression of EPHX2 mRNA Fenofibrate affects the expression of EPHX2 protein |
CTD |
PMID:20801182 PMID:29960002 PMID:32741897 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of EPRS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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Ero1a |
endoplasmic reticulum oxidoreductase 1 alpha |
increases expression |
EXP |
Fenofibrate results in increased expression of ERO1A mRNA |
CTD |
PMID:25596134 |
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NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
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Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[ESR1 protein results in increased susceptibility to Estradiol] inhibits the reaction [Fenofibrate results in decreased expression of CASP3 protein]; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; ESR1 protein inhibits the reaction [Fenofibrate results in decreased expression of CDKN1B protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of CCND1 protein]; ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein] |
CTD |
PMID:29134746 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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Etfa |
electron transfer flavoprotein subunit alpha |
increases expression |
ISO |
Fenofibrate results in increased expression of ETFA mRNA |
CTD |
PMID:25572481 |
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NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969
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Etfdh |
electron transfer flavoprotein dehydrogenase |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of ETFDH protein Fenofibrate results in increased expression of ETFDH mRNA |
CTD |
PMID:20118634 PMID:25572481 |
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NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
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Etnk2 |
ethanolamine kinase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ETNK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037
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F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F2 protein] |
CTD |
PMID:9681093 |
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NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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F7 |
coagulation factor VII |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Warfarin results in decreased expression of F7 protein] |
CTD |
PMID:9681093 |
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NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610
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G |
Fabp1 |
fatty acid binding protein 1 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of FABP1 mRNA Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of FABP1 mRNA] |
CTD |
PMID:17118139 PMID:24752549 PMID:27071702 PMID:32741897 |
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NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of FABP2 mRNA |
CTD |
PMID:17118139 |
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NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp3 |
fatty acid binding protein 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of FABP3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of FABP4 mRNA |
CTD |
PMID:11798191 PMID:12759900 PMID:25572481 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fads1 |
fatty acid desaturase 1 |
multiple interactions increases expression |
ISO |
beta-hydroxy simvastatin acid promotes the reaction [Fenofibrate results in increased expression of FADS1 mRNA]; Fenofibrate promotes the reaction [beta-hydroxy simvastatin acid results in increased expression of FADS1 mRNA] |
CTD |
PMID:17655842 |
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NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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Fah |
fumarylacetoacetate hydrolase |
increases expression |
ISO |
Fenofibrate results in increased expression of FAH mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
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Fam210a |
family with sequence similarity 210, member A |
affects expression |
EXP |
Fenofibrate affects the expression of FAM210A mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
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Fam222a |
family with sequence similarity 222, member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM222A mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:41,982,064...42,033,085
Ensembl chr12:41,986,780...42,033,682
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Fam241a |
family with sequence similarity 241 member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM241A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242
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Fam89a |
family with sequence similarity 89, member A |
increases expression |
ISO |
Fenofibrate results in increased expression of FAM89A mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631
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Fas |
Fas cell surface death receptor |
multiple interactions decreases expression |
ISO EXP |
Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]] fenofibrate co-treated with fructose diet increases expression of Fas mRNA in liver Fenofibrate results in decreased expression of FAS mRNA |
CTD RGD |
PMID:19593819 PMID:25596134 PMID:11934685 |
RGD:628329 |
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Fasn |
fatty acid synthase |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FASN protein] [Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of FASN mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of FASN mRNA] Fenofibrate results in increased expression of FASN mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA] |
CTD |
PMID:17118139 PMID:23063693 PMID:24534255 PMID:26973390 PMID:32730863 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fbp2 |
fructose-bisphosphatase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of FBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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Fbxo21 |
F-box protein 21 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBXO21 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:38,570,878...38,605,133
Ensembl chr12:38,571,023...38,605,133
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G |
Fbxo22 |
F-box protein 22 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of FBXO22 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148
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Fbxo3 |
F-box protein 3 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FBXO3 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:90,417,262...90,449,557
Ensembl chr 3:90,417,297...90,449,557
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G |
Fbxo30 |
F-box protein 30 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of FBXO30 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA] |
CTD |
PMID:21318169 PMID:25596134 |
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NCBI chr 1:5,655,341...5,671,558
Ensembl chr 1:5,655,339...5,672,441
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G |
Fbxo32 |
F-box protein 32 |
multiple interactions increases expression |
ISO |
Lovastatin promotes the reaction [Fenofibrate results in increased expression of FBXO32 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA] Fenofibrate results in increased expression of FBXO32 mRNA; Fenofibrate results in increased expression of FBXO32 protein |
CTD |
PMID:33408297 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fbxo36 |
F-box protein 36 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FBXO36 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 9:86,042,522...86,107,220
Ensembl chr 9:86,040,862...86,107,229
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G |
Fbxo9 |
f-box protein 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of FBXO9 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FDFT1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA] |
CTD |
PMID:23063693 |
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NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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G |
Fga |
fibrinogen alpha chain |
multiple interactions decreases expression |
ISO EXP |
PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA] |
CTD |
PMID:10216095 |
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NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
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G |
Fgb |
fibrinogen beta chain |
decreases expression |
EXP |
Fenofibrate results in decreased expression of FGB mRNA |
CTD |
PMID:10216095 |
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NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf21 |
fibroblast growth factor 21 |
increases expression |
ISO |
Fenofibrate results in increased expression of FGF21 mRNA; Fenofibrate results in increased expression of FGF21 protein |
CTD |
PMID:22338096 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgg |
fibrinogen gamma chain |
decreases expression |
EXP |
Fenofibrate results in decreased expression of FGG mRNA |
CTD |
PMID:10216095 |
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NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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G |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
affects expression |
EXP |
Fenofibrate affects the expression of FGR mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in increased expression of FIS1 protein] |
CTD |
PMID:32730863 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FKBP15 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
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G |
Fkbp8 |
FKBP prolyl isomerase 8 |
increases expression |
ISO |
Fenofibrate results in increased expression of FKBP8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
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G |
Fmo1 |
flavin containing dimethylaniline monoxygenase 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
multiple interactions decreases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of FMO5 mRNA Fenofibrate results in decreased expression of FMO5 mRNA |
CTD |
PMID:18253720 PMID:25572481 |
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NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
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G |
Fn1 |
fibronectin 1 |
affects expression multiple interactions |
EXP ISO |
Fenofibrate affects the expression of FN1 mRNA Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of FN1 protein] |
CTD |
PMID:20801182 PMID:28871336 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Foxo1 |
forkhead box O1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of FOXO1 mRNA; Fenofibrate results in increased expression of FOXO1 protein Lovastatin promotes the reaction [Fenofibrate results in increased expression of FOXO1 protein]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA] |
CTD |
PMID:33408297 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxq1 |
forkhead box Q1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of FOXQ1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 Ensembl chr17:32,912,744...32,915,377
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of G6PC1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GADD45A mRNA Fenofibrate results in increased expression of GADD45A mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:25596134 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Galt |
galactose-1-phosphate uridylyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of GALT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
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G |
Gars1 |
glycyl-tRNA synthetase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of GARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609
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G |
Gata4 |
GATA binding protein 4 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
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NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
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G |
Gbe1 |
1,4-alpha-glucan branching enzyme 1 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of GBE1 mRNA Fenofibrate results in increased expression of GBE1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
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G |
Gcat |
glycine C-acetyltransferase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of GCAT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression multiple interactions |
EXP ISO |
Fenofibrate results in decreased expression of GCLC mRNA Fenofibrate inhibits the reaction [tyloxapol results in decreased expression of GCLC protein] |
CTD |
PMID:25596134 PMID:36905866 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression |
ISO |
Fenofibrate results in increased expression of GCLM mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
Fenofibrate results in increased expression of GCNT3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
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G |
Gde1 |
glycerophosphodiester phosphodiesterase 1 |
affects expression |
EXP |
Fenofibrate affects the expression of GDE1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429
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G |
Gdf15 |
growth differentiation factor 15 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of GDF15 mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gk |
glycerol kinase |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of GK mRNA |
CTD |
PMID:25572481 PMID:32741897 |
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NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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G |
Gmnn |
geminin, DNA replication inhibitor |
increases expression |
EXP |
Fenofibrate results in increased expression of GMNN mRNA |
CTD |
PMID:32741897 |
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NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
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G |
Gnmt |
glycine N-methyltransferase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of GNMT mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
increases expression multiple interactions |
EXP |
Fenofibrate results in increased expression of GOT1 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GOT1 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of GOT2 mRNA |
CTD |
PMID:19652460 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
EXP |
Fenofibrate results in increased expression of GPAM mRNA |
CTD |
PMID:16707586 |
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NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of GPAT3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gphn |
gephyrin |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of GPHN mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases expression |
EXP ISO |
Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in increased expression of GPT protein] Fenofibrate results in increased expression of GPT protein Fenofibrate inhibits the reaction [tyloxapol results in increased expression of GPT protein] |
CTD |
PMID:27071702 PMID:36905866 PMID:38216941 PMID:39442682 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX1 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions increases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX2 mRNA] Fenofibrate results in increased expression of GPX2 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 PMID:31241159 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx3 |
glutathione peroxidase 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX3 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of GPX4 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Grm3 |
glutamate metabotropic receptor 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of GRM3 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
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G |
Grpel2 |
GrpE-like 2, mitochondrial |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of GRPEL2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr18:55,167,831...55,180,073
Ensembl chr18:55,168,209...55,180,180
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G |
Gsr |
glutathione-disulfide reductase |
increases expression |
EXP |
Fenofibrate results in increased expression of GSR mRNA |
CTD |
PMID:25596134 |
|
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of GSTA2 mRNA [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTA3 mRNA |
CTD |
PMID:18253720 |
|
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA Fenofibrate results in increased expression of GSTA5 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions decreases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA Fenofibrate results in decreased expression of GSTM2 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
multiple interactions decreases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA Fenofibrate results in decreased expression of GSTM3 mRNA |
CTD |
PMID:18253720 PMID:18775883 |
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NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gtse1 |
G-2 and S-phase expressed 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of GTSE1 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
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G |
H1f2 |
H1.2 linker histone, cluster member |
decreases expression |
ISO |
Fenofibrate results in decreased expression of H1-2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635
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G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
increases expression |
ISO |
Fenofibrate results in increased expression of HADH mRNA |
CTD |
PMID:24752549 |
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NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of HADHA mRNA Fenofibrate results in decreased expression of HADHA protein |
CTD |
PMID:16707586 PMID:17118139 PMID:20118634 PMID:25572481 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression decreases expression affects expression |
ISO EXP |
Fenofibrate results in increased expression of HADHB mRNA Fenofibrate results in decreased expression of HADHB protein Fenofibrate affects the expression of HADHB mRNA |
CTD |
PMID:17118139 PMID:20118634 PMID:20801182 PMID:24752549 PMID:25572481 |
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NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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G |
Hal |
histidine ammonia lyase |
decreases expression |
EXP |
Fenofibrate results in decreased expression of HAL mRNA |
CTD |
PMID:32741898 |
|
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hdc |
histidine decarboxylase |
increases expression |
EXP |
Fenofibrate results in increased expression of HDC mRNA; Fenofibrate results in increased expression of HDC protein |
CTD |
PMID:32741897 PMID:32741898 |
|
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
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G |
Hdgfl3 |
HDGF like 3 |
increases expression |
EXP |
Fenofibrate results in increased expression of HDGFL3 mRNA |
CTD |
PMID:17264098 |
|
NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719
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G |
Hectd1 |
HECT domain E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HECTD1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA |
CTD |
PMID:21318169 |
|
NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053
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G |
Herc3 |
HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of HERC3 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 4:87,952,202...88,042,492
Ensembl chr 4:87,952,274...88,042,488
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G |
Hes1 |
hes family bHLH transcription factor 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of HES1 mRNA] |
CTD |
PMID:31241159 |
|
NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions affects activity |
ISO EXP |
Fenofibrate results in increased expression of HIF1A mRNA Fenofibrate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Fenofibrate results in decreased expression of and results in increased degradation of HIF1A protein Fenofibrate affects the activity of HIF1A protein |
CTD |
PMID:17118139 PMID:25596134 PMID:34520103 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
increases expression |
EXP |
Fenofibrate results in increased expression of HILPDA mRNA |
CTD |
PMID:32741897 |
|
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression decreases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of HMGCR mRNA Fenofibrate results in decreased expression of HMGCR mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA] |
CTD |
PMID:16595124 PMID:23063693 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of HMGCS2 mRNA |
CTD |
PMID:25572481 PMID:27665778 PMID:32741897 |
|
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP ISO |
Fenofibrate results in increased expression of HMOX1 mRNA Fenofibrate results in increased expression of HMOX1 protein dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of HMOX1 protein] Fenofibrate results in increased expression of HMOX1 mRNA; Fenofibrate results in increased expression of HMOX1 protein |
CTD |
PMID:25596134 PMID:34520103 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hoga1 |
4-hydroxy-2-oxoglutarate aldolase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of HOGA1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:240,856,991...240,884,243
Ensembl chr 1:240,857,126...240,884,568
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of HRAS mRNA |
CTD |
PMID:18978307 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSD17B4 mRNA |
CTD |
PMID:17118139 PMID:25572481 |
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NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of HSDL2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
Hsf1 |
heat shock transcription factor 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of HSF1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSP90AA1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
multiple interactions increases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of HSP90B1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa13 |
heat shock protein family A (Hsp70) member 13 |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of HSPA13 mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895
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G |
Hspa4l |
heat shock protein family A (Hsp70) member 4 like |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA4L mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression multiple interactions |
EXP |
Fenofibrate results in decreased expression of HSPA5 mRNA Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein] |
CTD |
PMID:25596134 PMID:38216941 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA8 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPA9 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
affects expression multiple interactions increases expression |
EXP ISO |
Fenofibrate affects the expression of HSPB1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA] |
CTD |
PMID:20801182 PMID:21318169 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspb8 |
heat shock protein family B (small) member 8 |
multiple interactions increases expression |
ISO |
[PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA Fenofibrate results in increased expression of HSPB8 mRNA |
CTD |
PMID:21318169 |
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NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
affects expression |
EXP |
Fenofibrate affects the expression of HSPE1 mRNA |
CTD |
PMID:20801182 |
|
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Hsph1 |
heat shock protein family H (Hsp110) member 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of HSPH1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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G |
Htatip2 |
HIV-1 Tat interactive protein 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of HTATIP2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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G |
Iars1 |
isoleucyl-tRNA synthetase 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of IARS1 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of ICAM1 mRNA] |
CTD |
PMID:20580385 PMID:21300114 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ID2 mRNA |
CTD |
PMID:11798191 |
|
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Idh3b |
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta |
increases expression |
ISO |
Fenofibrate results in increased expression of IDH3B mRNA |
CTD |
PMID:24752549 |
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NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982
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G |
Iffo1 |
intermediate filament family orphan 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of IFFO1 mRNA |
CTD |
PMID:16707586 |
|
NCBI chr 4:157,945,075...157,962,302
Ensembl chr 4:157,945,107...157,962,302
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G |
Ifng |
interferon gamma |
multiple interactions |
EXP |
Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein] |
CTD |
PMID:20631892 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf2r |
insulin-like growth factor 2 receptor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of IGF2R mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15968640 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il17rb |
interleukin 17 receptor B |
decreases expression |
EXP |
Fenofibrate results in decreased expression of IL17RB mRNA |
CTD |
PMID:25596134 |
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NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL1B mRNA] Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Fenofibrate results in decreased susceptibility to [IFNG protein co-treated with IL1B protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]] |
CTD |
PMID:15968640 PMID:20631892 PMID:21300114 PMID:31241159 PMID:32613381 PMID:36988379 PMID:38278497 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression affects response to substance |
ISO |
[Fenofibrate co-treated with Alitretinoin] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of IL6 mRNA]; Fenofibrate inhibits the reaction [tyloxapol results in increased expression of IL6 mRNA]; Fenofibrate promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]] Fenofibrate results in increased expression of IL6 mRNA IL6 promoter polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:15968640 PMID:16607077 PMID:19593819 PMID:21300114 PMID:25035112 PMID:31241159 PMID:37076581 PMID:38278497 PMID:39442682 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [Fructose results in increased secretion of INS1 protein] |
CTD |
PMID:26973390 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Fenofibrate inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] |
CTD |
PMID:32613381 |
|
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insig1 |
insulin induced gene 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of INSIG1 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Insig2 |
insulin induced gene 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of INSIG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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G |
Irak2 |
interleukin-1 receptor-associated kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of IRAK2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of IRF7 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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G |
Itch |
itchy E3 ubiquitin protein ligase |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA] |
CTD |
PMID:21318169 |
|
NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543
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G |
Itfg2 |
integrin alpha FG-GAP repeat containing 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of ITFG2 mRNA |
CTD |
PMID:25596134 |
|
NCBI chr 4:161,684,249...161,698,315
Ensembl chr 4:161,684,249...161,698,422
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of ITGB1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb3 |
integrin subunit beta 3 |
affects expression |
EXP |
Fenofibrate affects the expression of ITGB3 mRNA |
CTD |
PMID:20801182 |
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NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Glucose results in increased expression of JUN protein] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of JUN mRNA; Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of JUN mRNA] |
CTD |
PMID:16600694 PMID:18978307 PMID:31016362 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnk13 |
potassium two pore domain channel subfamily K member 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of KCNK13 mRNA |
CTD |
PMID:25572481 PMID:25596134 |
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NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Kif22 |
kinesin family member 22 |
increases expression |
EXP |
Fenofibrate results in increased expression of KIF22 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
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G |
Kifc1 |
kinesin family member C1 |
increases expression |
EXP |
Fenofibrate results in increased expression of KIFC1 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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G |
Klf10 |
KLF transcription factor 10 |
decreases expression increases expression |
ISO |
Fenofibrate results in decreased expression of KLF10 mRNA Fenofibrate results in increased expression of KLF10 mRNA |
CTD |
PMID:11798191 PMID:25572481 |
|
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Klf11 |
KLF transcription factor 11 |
increases expression |
ISO |
Fenofibrate results in increased expression of KLF11 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:41,285,699...41,297,548
Ensembl chr 6:41,285,842...41,297,550
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G |
Krt18 |
keratin 18 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT18 protein |
CTD |
PMID:18978307 |
|
NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 Ensembl chr10:133,157,475...133,161,166
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G |
Krt23 |
keratin 23 |
increases expression |
EXP |
Fenofibrate results in increased expression of KRT23 mRNA |
CTD |
PMID:32741897 |
|
NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
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G |
Krt8 |
keratin 8 |
multiple interactions |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of KRT8 protein |
CTD |
PMID:18978307 |
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NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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G |
Krtap1-1 |
keratin associated protein 1-1 |
increases expression |
EXP |
Fenofibrate results in increased expression of KRTAP1-5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr10:84,545,765...84,546,331
Ensembl chr10:84,545,580...84,546,354
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G |
Lama4 |
laminin subunit alpha 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of LAMA4 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lars1 |
leucyl-tRNA synthetase 1 |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of LARS1 mRNA Fenofibrate results in decreased expression of LARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
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G |
Lbh |
LBH regulator of WNT signaling pathway |
increases expression |
ISO |
Fenofibrate results in increased expression of LBH mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079
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G |
Ldhb |
lactate dehydrogenase B |
increases expression |
ISO |
Fenofibrate results in increased expression of LDHB mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
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G |
Lep |
leptin |
multiple interactions |
EXP ISO |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in increased expression of LEP mRNA]; Fenofibrate inhibits the reaction [Fructose results in increased expression of LEP mRNA] Fenofibrate inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased secretion of LEP protein] |
CTD |
PMID:26973390 PMID:32929351 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lgals1 |
galectin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of LGALS1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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G |
Lifr |
LIF receptor subunit alpha |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LIFR mRNA |
CTD |
PMID:11798191 |
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NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
affects expression |
EXP |
Fenofibrate affects the expression of LMCD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
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G |
Lnx1 |
ligand of numb-protein X 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr14:33,514,429...33,617,086
Ensembl chr14:33,514,436...33,617,086
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G |
Lpcat2 |
lysophosphatidylcholine acyltransferase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of LPCAT2 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr19:14,088,389...14,152,742
Ensembl chr19:14,089,686...14,152,829
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G |
Lpcat3 |
lysophosphatidylcholine acyltransferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of LPCAT3 mRNA |
CTD |
PMID:25572481 |
|
NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
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G |
Lpl |
lipoprotein lipase |
increases expression multiple interactions increases activity |
ISO EXP |
Fenofibrate results in increased expression of LPL mRNA; Fenofibrate results in increased expression of LPL protein PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein] PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein] Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of LPL mRNA] Fenofibrate results in increased activity of LPL protein |
CTD |
PMID:8593127 PMID:11798191 PMID:16595124 PMID:24752549 PMID:27071702 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Lrrc31 |
leucine rich repeat containing 31 |
increases expression |
ISO |
Fenofibrate results in increased expression of LRRC31 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:112,702,844...112,725,431
Ensembl chr 2:112,700,136...112,724,322
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G |
Lrsam1 |
leucine rich repeat and sterile alpha motif containing 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154
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G |
Lss |
lanosterol synthase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of LSS mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA] |
CTD |
PMID:23063693 |
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NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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G |
Ltn1 |
listerin E3 ubiquitin protein ligase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of LTN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886
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G |
Ly6d |
lymphocyte antigen 6 family member D |
increases expression |
ISO |
Fenofibrate results in increased expression of LY6D mRNA |
CTD |
PMID:17118139 |
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NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
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G |
Lyrm1 |
LYR motif containing 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of LYRM1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:174,284,116...174,305,053
Ensembl chr 1:174,284,602...174,305,053
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G |
Lyz2 |
lysozyme 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of LYZ2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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G |
Mafg |
MAF bZIP transcription factor G |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of MAFG mRNA Fenofibrate results in increased expression of MAFG mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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G |
Man1a1 |
mannosidase, alpha, class 1A, member 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MAN1A mRNA |
CTD |
PMID:16707586 |
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NCBI chr20:33,202,509...33,385,747
Ensembl chr20:33,202,517...33,385,824
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G |
Man1a2 |
mannosidase, alpha, class 1A, member 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MAN1A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332
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G |
Maob |
monoamine oxidase B |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA |
CTD |
PMID:18253720 |
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NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of MAP1LC3A mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA |
CTD |
PMID:21318169 |
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NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [tyloxapol results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:36905866 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map3k13 |
mitogen-activated protein kinase kinase kinase 13 |
increases expression |
EXP |
Fenofibrate results in increased expression of MAP3K13 mRNA |
CTD |
PMID:32741897 |
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NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
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G |
Mat2a |
methionine adenosyltransferase 2A |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MAT2A mRNA |
CTD |
PMID:16569247 |
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NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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G |
Mc1r |
melanocortin 1 receptor |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of MC1R mRNA [Fenofibrate results in decreased expression of MC1R mRNA] which results in decreased chemical synthesis of Melanins |
CTD |
PMID:23872139 |
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NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192
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G |
Mdh2 |
malate dehydrogenase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of MDH mRNA |
CTD |
PMID:24752549 |
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NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MDM2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Me1 |
malic enzyme 1 |
affects expression increases expression multiple interactions |
EXP ISO |
Fenofibrate affects the expression of ME1 mRNA Fenofibrate results in increased expression of ME1 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA] |
CTD |
PMID:20801182 PMID:23063693 PMID:25596134 PMID:27071702 |
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NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
increases expression |
ISO |
Fenofibrate results in increased expression of MERTK mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
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G |
Mfn2 |
mitofusin 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of MFN2 protein] |
CTD |
PMID:32730863 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mfsd2a |
MFSD2 lysolipid transporter A, lysophospholipid |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MFSD2A mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
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G |
Mgll |
monoglyceride lipase |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of MGLL mRNA |
CTD |
PMID:11798191 PMID:17118139 PMID:27665778 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA Fenofibrate results in increased expression of MGMT mRNA |
CTD |
PMID:17264098 PMID:18253720 |
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NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgrn1 |
mahogunin ring finger 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of MGRN1 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315
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G |
Mgst3 |
microsomal glutathione S-transferase 3 |
increases expression |
ISO |
Fenofibrate results in increased expression of MGST3 mRNA |
CTD |
PMID:11798191 |
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NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
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G |
Mitf |
melanocyte inducing transcription factor |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MITF mRNA; Fenofibrate results in decreased expression of MITF protein |
CTD |
PMID:23872139 |
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NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of MKI67 mRNA; Fenofibrate results in increased expression of MKI67 protein |
CTD |
PMID:17264098 PMID:32741897 PMID:39442682 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mlh1 |
mutL homolog 1 |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of MLH1 mRNA; [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MLH1 mRNA Fenofibrate results in increased expression of MLH1 mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
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G |
Mlycd |
malonyl-CoA decarboxylase |
multiple interactions |
EXP |
[Fenofibrate co-treated with resveratrol] inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of MLYCD mRNA]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA] |
CTD |
PMID:14641110 PMID:26973390 |
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NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
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G |
Mmd |
monocyte to macrophage differentiation-associated |
increases expression |
ISO |
Fenofibrate results in increased expression of MMD mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528
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G |
Mmp1 |
matrix metallopeptidase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP1 protein |
CTD |
PMID:25545733 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp19 |
matrix metallopeptidase 19 |
increases expression |
EXP |
Fenofibrate results in increased expression of MMP19 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP2 protein |
CTD |
PMID:25545733 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp7 |
matrix metallopeptidase 7 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MMP7 protein |
CTD |
PMID:25545733 |
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NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [Dinoprostone results in increased expression of MMP9 mRNA]; Fenofibrate inhibits the reaction [Dinoprostone results in increased secretion of MMP9 protein]; Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased secretion of MMP9 protein] Fenofibrate results in decreased expression of MMP9 protein |
CTD |
PMID:19880272 PMID:21075133 PMID:25545733 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mrap |
melanocortin 2 receptor accessory protein |
increases expression |
ISO |
Fenofibrate results in increased expression of MRAP mRNA |
CTD |
PMID:11798191 |
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NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024
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G |
Ms4a10 |
membrane spanning 4-domains A10 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MS4A10 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:207,611,312...207,624,452
Ensembl chr 1:207,611,312...207,624,452
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G |
Msc |
musculin |
decreases expression |
EXP |
Fenofibrate results in decreased expression of MSC mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:4,547,335...4,553,206
Ensembl chr 5:4,547,405...4,553,203
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G |
Msmo1 |
methylsterol monooxygenase 1 |
affects expression |
EXP |
Fenofibrate affects the expression of MSMO1 mRNA |
CTD |
PMID:20801182 |
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NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
EXP |
Fenofibrate results in increased expression of MTTP mRNA |
CTD |
PMID:32741897 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions increases expression |
ISO EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA Fenofibrate results in increased expression of MYC mRNA |
CTD |
PMID:18978307 PMID:32741897 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Mylk |
myosin light chain kinase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of MYLK mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
N4bp2l1 |
NEDD4 binding protein 2-like 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of N4BP2L1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257
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G |
Nacc1 |
nucleus accumbens associated 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of NACC1 mRNA |
CTD |
PMID:17264098 |
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NCBI chr19:23,468,688...23,486,528
Ensembl chr19:23,468,419...23,486,528
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G |
Nampt |
nicotinamide phosphoribosyltransferase |
increases expression |
EXP |
Fenofibrate results in increased expression of NAMPT mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
affects expression |
EXP |
Fenofibrate affects the expression of NARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:57,989,308...58,005,584
Ensembl chr18:57,989,308...58,005,622
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G |
Nat8f3 |
N-acetyltransferase 8 (GCN5-related) family member 3 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NAT8F3 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500
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G |
Nbn |
nibrin |
multiple interactions increases expression |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NBN mRNA Fenofibrate results in increased expression of NBN mRNA |
CTD |
PMID:17264098 PMID:18253720 PMID:18775883 |
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NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
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G |
Nceh1 |
neutral cholesterol ester hydrolase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of NCEH1 mRNA |
CTD |
PMID:27665778 |
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NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
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G |
Ndufab1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression |
ISO |
Fenofibrate results in increased expression of NDUFAB1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of NEDD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nedd9 |
neural precursor cell expressed, developmentally down-regulated 9 |
decreases expression |
ISO EXP |
Fenofibrate results in decreased expression of NEDD9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
multiple interactions |
EXP |
EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]; Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]] |
CTD |
PMID:22198280 |
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NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases activity decreases expression affects activity |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 protein Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein] Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NFE2L2 protein] Fenofibrate results in increased activity of NFE2L2 protein Fenofibrate results in decreased expression of NFE2L2 mRNA Fenofibrate affects the activity of NFE2L2 protein |
CTD |
PMID:18775883 PMID:25596134 PMID:30114225 PMID:30203046 PMID:31241159 PMID:32730863 More...
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions affects localization |
ISO |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of NFKB1 protein] Fenofibrate affects the localization of NFKB1 protein |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression |
ISO |
Fenofibrate inhibits the reaction [ALB protein modified form results in increased degradation of NFKBIA protein] Fenofibrate results in decreased expression of NFKBIA protein modified form |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NFKBIB mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NFKBIB mRNA |
CTD |
PMID:18253720 PMID:21999347 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Nim1k |
NIM1 serine/threonine protein kinase |
increases expression |
EXP |
Fenofibrate results in increased expression of NIM1K mRNA |
CTD |
PMID:32741897 |
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NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762
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G |
Ninj1 |
ninjurin 1 |
affects expression |
EXP |
Fenofibrate affects the expression of NINJ1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Cyclophosphamide results in increased expression of NLRP3 protein] |
CTD |
PMID:38278497 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nmur1 |
neuromedin U receptor 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of NMUR1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:87,033,231...87,038,070
Ensembl chr 9:87,033,279...87,036,684
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G |
Nnmt |
nicotinamide N-methyltransferase |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of NNMT mRNA |
CTD |
PMID:18253720 |
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NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO EXP |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 mRNA; [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of NOS2 protein |
CTD |
PMID:21300114 PMID:21999347 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions increases phosphorylation increases activity |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate results in increased activity of NOS3 protein]; Fenofibrate inhibits the reaction [Wortmannin results in decreased phosphorylation of NOS3 protein]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] Fenofibrate results in increased phosphorylation of NOS3 protein |
CTD |
PMID:16442496 PMID:20580385 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch1 |
notch receptor 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH1 mRNA] |
CTD |
PMID:31241159 |
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NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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G |
Notch3 |
notch receptor 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 mRNA]; Fenofibrate inhibits the reaction [triptolide results in increased expression of NOTCH3 protein] |
CTD |
PMID:31241159 |
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NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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G |
Nppa |
natriuretic peptide A |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Doxorubicin results in decreased expression of NPPA mRNA] |
CTD |
PMID:17531194 |
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NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to NPPB promoter]]; Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD |
PMID:22198280 |
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NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions increases expression |
ISO EXP |
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]]; pyrazolanthrone inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA] [Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of NR0B2 mRNA; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of IL6 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with Fenofibrate] results in increased expression of CYP4A14 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of COL1A1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of FAS mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL6 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SREBF1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TGFB1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]] Fenofibrate results in increased expression of NR0B2 mRNA; Fenofibrate results in increased expression of NR0B2 protein |
CTD |
PMID:19593819 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of NR1H2 mRNA NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA] |
CTD |
PMID:19201410 PMID:23063693 |
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NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression multiple interactions affects response to substance |
ISO |
Fenofibrate results in increased expression of NR1H3 mRNA NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of ACACB mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of HMGCR mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LSS mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SQLE mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SREBF1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA] NR1H3 protein affects the susceptibility to Fenofibrate [Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA] |
CTD |
PMID:19201410 PMID:23063693 PMID:24534255 PMID:25949234 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA fenofibrate increases expression of Nr1h4 mRNA in steatotic liver |
CTD RGD |
PMID:24534255 PMID:30257410 |
RGD:15090799 |
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
Fenofibrate binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:20024649 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
affects localization increases activity multiple interactions increases expression |
ISO EXP |
Fenofibrate affects the localization of NR1I3 protein Fenofibrate results in increased activity of NR1I3 protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; Fenofibrate binds to and results in increased activity of NR1I3 protein alternative form Fenofibrate results in increased expression of NR1I3 mRNA |
CTD |
PMID:17962186 PMID:19118567 PMID:24534255 PMID:30203046 PMID:31312845 PMID:32741897 More...
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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G |
Nrep |
neuronal regeneration related protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NREP mRNA |
CTD |
PMID:25596134 |
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NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Fenofibrate results in increased expression of NSDHL mRNA |
CTD |
PMID:11798191 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Ntpcr |
nucleoside-triphosphatase, cancer-related |
affects expression |
EXP |
Fenofibrate affects the expression of NTPCR mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:53,701,496...53,715,260
Ensembl chr19:53,695,976...53,715,202
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G |
Nuak1 |
NUAK family kinase 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of NUAK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:19,330,034...19,401,918
Ensembl chr 7:19,329,933...19,401,913
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G |
Oasl |
2'-5'-oligoadenylate synthetase-like |
increases expression |
ISO |
Fenofibrate results in increased expression of OASL mRNA |
CTD |
PMID:25572481 |
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NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of OPA1 protein] |
CTD |
PMID:32730863 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Orai3 |
ORAI calcium release-activated calcium modulator 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of ORAI3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:182,381,196...182,386,055
Ensembl chr 1:182,344,293...182,386,052
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of OSGIN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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G |
P4ha1 |
prolyl 4-hydroxylase subunit alpha 1 |
affects expression |
EXP |
Fenofibrate affects the expression of P4HA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
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G |
P4hb |
prolyl 4-hydroxylase subunit beta |
affects expression |
EXP |
Fenofibrate affects the expression of P4HB mRNA |
CTD |
PMID:20801182 |
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NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of PANK1 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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G |
Pbk |
PDZ binding kinase |
increases expression |
EXP |
Fenofibrate results in increased expression of PBK mRNA |
CTD |
PMID:32741897 |
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NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PCK1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
Fenofibrate results in increased expression of PCK2 mRNA |
CTD |
PMID:16569247 PMID:24752549 |
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NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of PCNA protein Fenofibrate results in increased expression of PCNA protein ESR1 protein inhibits the reaction [Fenofibrate results in increased expression of PCNA protein]; Estradiol inhibits the reaction [Fenofibrate results in increased expression of PCNA protein] |
CTD |
PMID:18978307 PMID:29134746 PMID:39442682 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcsk9 |
proprotein convertase subtilisin/kexin type 9 |
increases expression |
ISO |
Fenofibrate results in increased expression of PCSK9 protein |
CTD |
PMID:21411093 |
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NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
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G |
Pdia5 |
protein disulfide isomerase family A, member 5 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PDIA5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PDK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of PDK4 mRNA |
CTD |
PMID:17118139 PMID:19395589 PMID:25572481 PMID:25596134 PMID:27665778 PMID:32741897 More...
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdlim1 |
PDZ and LIM domain 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PDLIM1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdrg1 |
p53 and DNA damage regulated 1 |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858 Ensembl chr 3:141,476,501...141,483,858
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G |
Pemt |
phosphatidylethanolamine N-methyltransferase |
increases expression |
ISO |
Fenofibrate results in increased expression of PEMT mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
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G |
Pex11a |
peroxisomal biogenesis factor 11 alpha |
affects expression increases expression |
EXP ISO |
Fenofibrate affects the expression of PEX11A mRNA Fenofibrate results in increased expression of PEX11A mRNA |
CTD |
PMID:20801182 PMID:25572481 PMID:27665778 PMID:32741897 |
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NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
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G |
Pgm1 |
phosphoglucomutase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PGM1 mRNA |
CTD |
PMID:24752549 |
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NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
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G |
Phgdh |
phosphoglycerate dehydrogenase |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of PHGDH mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:185,906,962...185,936,054
Ensembl chr 2:185,906,966...185,935,944
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G |
Phlda1 |
pleckstrin homology-like domain, family A, member 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PHLDA1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 7:46,967,433...46,969,637
Ensembl chr 7:46,967,409...46,969,861
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G |
Phlda3 |
pleckstrin homology-like domain, family A, member 3 |
affects expression |
EXP |
Fenofibrate affects the expression of PHLDA3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
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G |
Pik3c2g |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PIK3C2G mRNA |
CTD |
PMID:16707586 |
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NCBI chr 4:172,483,752...172,851,623
Ensembl chr 4:172,484,345...172,850,544
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G |
Pir |
pirin |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PIR mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:30,108,536...30,219,269
Ensembl chr X:30,108,538...30,219,218
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G |
Pja2 |
praja ring finger ubiquitin ligase 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PJA2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 9:103,956,678...104,006,763
Ensembl chr 9:103,956,678...104,006,783
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G |
Pkib |
cAMP-dependent protein kinase inhibitor beta |
increases expression |
ISO |
Fenofibrate results in increased expression of PKIB mRNA |
CTD |
PMID:25572481 |
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NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187
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G |
Pklr |
pyruvate kinase L/R |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PKLR mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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G |
Pla1a |
phospholipase A1 member A |
increases expression |
ISO |
Fenofibrate results in increased expression of PLA1A mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779
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G |
Pla2g7 |
phospholipase A2 group VII |
decreases activity multiple interactions |
ISO |
Fenofibrate results in decreased activity of PLA2G7 protein [orlistat co-treated with Fenofibrate] results in decreased activity of PLA2G7 protein |
CTD |
PMID:16911813 |
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NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
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G |
Plcxd3 |
phosphatidylinositol-specific phospholipase C, X domain containing 3 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PLCXD3 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN1 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of PLIN2 mRNA Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:24534255 PMID:25572481 PMID:25596134 PMID:27665778 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin4 |
perilipin 4 |
increases expression |
ISO |
Fenofibrate results in increased expression of PLIN4 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
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G |
Plin5 |
perilipin 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of PLIN5 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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G |
Pltp |
phospholipid transfer protein |
increases expression |
ISO |
Fenofibrate results in increased expression of PLTP mRNA |
CTD |
PMID:11798191 |
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NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
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G |
Pmepa1 |
prostate transmembrane protein, androgen induced 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PMEPA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454
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G |
Pml |
PML nuclear body scaffold |
multiple interactions |
ISO |
Fenofibrate promotes the reaction [Arsenic Trioxide results in decreased expression of PML protein mutant form] |
CTD |
PMID:32929351 |
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NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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G |
Podxl |
podocalyxin-like |
decreases expression |
ISO EXP |
Fenofibrate results in decreased expression of PODXL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
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G |
Pon1 |
paraoxonase 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PON1 protein |
CTD |
PMID:16123850 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of POR mRNA |
CTD |
PMID:16707586 PMID:25572481 |
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NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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G |
Ppan |
peter pan homolog |
affects expression |
EXP |
Fenofibrate affects the expression of PPAN mRNA |
CTD |
PMID:25596134 |
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NCBI chr 8:19,423,908...19,427,941
Ensembl chr 8:19,423,961...19,427,938
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
decreases expression multiple interactions increases response to substance increases activity decreases response to substance increases expression affects response to substance |
ISO EXP |
Fenofibrate results in decreased expression of PPARA mRNA fenofibrate co-treated with fructose diet decreases expression of ppara mRNA in liver PPARA protein results in increased susceptibility to Fenofibrate Fenofibrate results in increased activity of PPARA protein PPARA gene mutant form results in decreased susceptibility to Fenofibrate [Fenofibrate co-treated with Fatty Acids, Nonesterified] results in increased expression of PPARA mRNA; ESR1 protein inhibits the reaction [Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Estradiol inhibits the reaction [ESR1 protein inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]]; Estradiol inhibits the reaction [Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [ESR1 protein binds to PPARA protein]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [Fatty Acids, Nonesterified results in decreased expression of PPARA protein]; NR1H3 protein affects the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA protein inhibits the reaction [Fenofibrate results in decreased expression of APOA1 mRNA]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA protein promotes the reaction [Fenofibrate results in increased expression of UCP2 protein] [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Fatty Acids, Nonesterified; [Fenofibrate binds to and results in increased activity of PPARA protein] which affects the abundance of Triglycerides; [Fenofibrate results in increased activity of PPARA protein] which results in decreased abundance of Adenosine Triphosphate; [Fenofibrate results in increased activity of PPARA protein] which results in increased expression of TRIB3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of ASB6 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of BRCC3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC14 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC19 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of DNAJC2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of FKBP15 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HECTD1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of HSPB8 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MAP1LC3A mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of MGRN1 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SMPD3 mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of TOPORS mRNA; [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of UBR2 mRNA; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [Zoledronic Acid results in decreased expression of PPARA mRNA]; Fenofibrate promotes the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]; Fenofibrate results in increased expression of and results in increased activity of PPARA protein; Lipopolysaccharides inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of PPARA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACA mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACACB mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACLY mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACOX1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ACSL1 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A10 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of CYP4A14 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ELOVL6 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FASN mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of LPL protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of ME1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of NR1H3 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of UCP2 protein]; PPARA promotes the reaction [Fenofibrate results in decreased expression of FGA mRNA]; PPARA protein affects the reaction [Fenofibrate affects the expression of BRAP mRNA]; PPARA protein affects the reaction [Fenofibrate promotes the reaction [APOA1 protein results in increased secretion of Lipids]]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ANAPC11 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CISH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of CYLD mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of DNAJB4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of HSPA13 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of ITCH mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LNX1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of LRSAM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PDRG1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RBJ mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of UBE2R2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of URM1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of USP36 mRNA]; PPARA protein affects the reaction [Fenofibrate results in decreased expression of WSB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ACADM mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ARIH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATE1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ATG7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CANX mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CBLB mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of CNOT4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJB6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of DNAJC5 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of ENC1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO3 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO30 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FBXO32 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of FOXO1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of GRPEL2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AA1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSP90AB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA4L mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA8 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPA9 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPB1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of HSPH1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of NEDD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PJA2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SOCS6 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of SPOP mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR1B mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TOR3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIM63 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of TRIP12 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE2Q2 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of UBE3A mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP10 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP22 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP38 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP7 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USP9X mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of USPL1 mRNA]; PPARA protein affects the reaction [Fenofibrate results in increased expression of VCPIP1 mRNA] Fenofibrate results in increased expression of PPARA mRNA; Fenofibrate results in increased expression of PPARA protein PPARA protein results in increased susceptibility to Fenofibrate; PPARA results in increased susceptibility to Fenofibrate [Fenofibrate binds to and results in increased activity of PPARA protein] which results in increased expression of UCP2 mRNA; EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]]; Fenofibrate binds to and results in increased activity of PPARA protein; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Fenofibrate inhibits the reaction [Fructose results in decreased expression of and results in decreased activity of PPARA protein]; Fenofibrate inhibits the reaction [Pyrazinamide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of PPARA protein]; Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]; Fenofibrate promotes the reaction [PPARA protein results in increased expression of MLYCD mRNA]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein promotes the reaction [NFATC4 protein binds to GATA4 protein]]]; PPARA mutant form inhibits the reaction [Fenofibrate inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]] |
CTD RGD |
PMID:7983038 PMID:10216095 PMID:11341955 PMID:11798191 PMID:11934685 PMID:12759900 PMID:14641110 PMID:15299082 PMID:15968640 PMID:16569247 PMID:17201732 PMID:17655842 PMID:18300857 PMID:18338635 PMID:18356826 PMID:18812576 PMID:19118567 PMID:19124612 PMID:19201410 PMID:19445040 PMID:19569716 PMID:19593819 PMID:20520642 PMID:21300114 PMID:21318169 PMID:22198280 PMID:23063693 PMID:24735863 PMID:24752549 PMID:24986865 PMID:25035112 PMID:25689681 PMID:25949234 PMID:26989860 PMID:27071702 PMID:28743512 PMID:28871336 PMID:29134746 PMID:30203046 PMID:30611848 PMID:33408297 PMID:39442682 PMID:11934685 More...
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RGD:628329 |
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of PPARD mRNA Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein] |
CTD |
PMID:18338635 PMID:19201410 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression affects activity multiple interactions |
ISO EXP |
Fenofibrate results in increased expression of PPARG mRNA Fenofibrate affects the activity of PPARG protein [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA |
CTD |
PMID:19201410 PMID:24534255 PMID:25596134 PMID:28034800 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA] Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of PPARGC1A protein] |
CTD |
PMID:28871336 PMID:32730863 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppcs |
phosphopantothenoylcysteine synthetase |
increases expression |
EXP |
Fenofibrate results in increased expression of PPCS mRNA |
CTD |
PMID:27665778 |
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NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
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G |
Ppm1d |
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
decreases expression |
EXP |
Fenofibrate results in decreased expression of PPM1D mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:70,172,603...70,208,607
Ensembl chr10:70,172,603...70,208,607
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of PPP1R15A mRNA Fenofibrate results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp1r15b |
protein phosphatase 1, regulatory subunit 15B |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PPP1R15B mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PPP1R15B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737
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G |
Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
multiple interactions decreases expression |
ISO |
PPARA protein affects the reaction [Fenofibrate results in decreased expression of PPP3CA mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions decreases response to substance |
ISO |
PRKAA1 protein affects the reaction [Fenofibrate results in decreased susceptibility to ALB protein modified form]; PRKAA1 protein affects the reaction [Fenofibrate results in increased abundance of Nitric Oxide]; PRKAA1 protein affects the reaction [Fenofibrate results in increased activity of NOS3 protein] PRKAA1 gene mutant form results in decreased susceptibility to Fenofibrate |
CTD |
PMID:20580385 PMID:25545733 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkab1 |
protein kinase AMP-activated non-catalytic subunit beta 1 |
decreases expression increases phosphorylation multiple interactions |
ISO |
Fenofibrate results in decreased expression of PRKAB1 mRNA Fenofibrate results in increased phosphorylation of PRKAB1 protein PPARA protein affects the reaction [Fenofibrate results in decreased expression of PRKAB1 mRNA] |
CTD |
PMID:21318169 PMID:25545733 |
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NCBI chr12:40,588,140...40,598,673
Ensembl chr12:40,588,211...40,598,661
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G |
Prkab2 |
protein kinase AMP-activated non-catalytic subunit beta 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PRKAB2 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of PRKAB2 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
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G |
Prkag1 |
protein kinase AMP-activated non-catalytic subunit gamma 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of PRKAG1 protein |
CTD |
PMID:25545733 |
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NCBI chr 7:129,963,105...129,980,532
Ensembl chr 7:129,963,105...129,980,561
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G |
Prodh |
proline dehydrogenase |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PRODH mRNA |
CTD |
PMID:25572481 |
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NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305
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G |
Prrg4 |
proline rich and Gla domain 4 |
increases expression |
EXP |
Fenofibrate results in increased expression of PRRG4 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
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G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
Fenofibrate affects the reaction [PSEN1 protein affects the cleavage of APP protein] |
CTD |
PMID:17962197 |
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NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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G |
Psmb2 |
proteasome 20S subunit beta 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMB2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMB2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137
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G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMC6 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMC6 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055
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G |
Psmd4 |
proteasome 26S subunit ubiquitin receptor, non-ATPase 4 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of PSMD4 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of PSMD4 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of PTGS1 mRNA |
CTD |
PMID:18253720 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:21300114 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
affects expression |
EXP |
Fenofibrate affects the expression of PTPRF mRNA |
CTD |
PMID:20801182 |
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NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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G |
Ptprq |
protein tyrosine phosphatase, receptor type, Q |
decreases expression |
ISO |
Fenofibrate results in decreased expression of PTPRQ mRNA |
CTD |
PMID:25572481 |
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NCBI chr 7:42,834,455...43,016,807
Ensembl chr 7:42,837,109...43,016,917
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G |
Pygl |
glycogen phosphorylase L |
increases expression |
EXP |
Fenofibrate results in increased expression of PYGL mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
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G |
Qpct |
glutaminyl-peptide cyclotransferase |
increases expression |
EXP |
Fenofibrate results in increased expression of QPCT mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711
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G |
Rab30 |
RAB30, member RAS oncogene family |
increases expression |
EXP |
Fenofibrate results in increased expression of RAB30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181
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G |
Rab31 |
RAB31, member RAS oncogene family |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RAB31 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
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G |
Rabgef1 |
RAB guanine nucleotide exchange factor 1 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of RABGEF1 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RABGEF1 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744
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G |
Rad50 |
RAD50 double strand break repair protein |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RAD50 mRNA |
CTD |
PMID:18253720 |
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NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
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G |
Rad51b |
RAD51 paralog B |
increases expression |
ISO |
Fenofibrate results in increased expression of RAD51B mRNA |
CTD |
PMID:11798191 |
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NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
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Raet1e |
retinoic acid early transcript 1E |
increases expression |
ISO |
Fenofibrate results in increased expression of RAET1E mRNA |
CTD |
PMID:11798191 |
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NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755
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G |
Ramp2 |
receptor activity modifying protein 2 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RAMP2 mRNA |
CTD |
PMID:11798191 |
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NCBI chr10:86,187,366...86,190,692
Ensembl chr10:86,188,812...86,231,829
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G |
Rara |
retinoic acid receptor, alpha |
multiple interactions decreases expression |
EXP ISO |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA Fenofibrate results in decreased expression of RARA mRNA |
CTD |
PMID:18253720 PMID:25596134 |
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NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
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G |
Rarb |
retinoic acid receptor, beta |
multiple interactions |
EXP |
[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA |
CTD |
PMID:18253720 |
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NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
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G |
Rbp2 |
retinol binding protein 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of RBP2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473
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G |
Rbx1 |
ring-box 1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RBX1 mRNA |
CTD |
PMID:21318169 |
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NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
Fenofibrate affects the localization of and results in decreased activity of RELA protein; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Glucose results in increased expression of RELA protein]; Fenofibrate results in decreased localization of and results in decreased activity of RELA protein [Fenofibrate co-treated with Sodium Glutamate] results in increased expression of RELA protein; Fenofibrate inhibits the reaction [Dietary Fats results in increased expression of RELA protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]] |
CTD |
PMID:16600694 PMID:20520642 PMID:20580385 PMID:21999347 PMID:25545733 PMID:36988379 PMID:38216941 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Retn |
resistin |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased secretion of RETN protein] |
CTD |
PMID:32929351 |
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NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
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G |
Retsat |
retinol saturase |
increases expression |
ISO |
Fenofibrate results in increased expression of RETSAT mRNA |
CTD |
PMID:11798191 |
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NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
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G |
Rgs16 |
regulator of G-protein signaling 16 |
increases expression |
EXP |
Fenofibrate results in increased expression of RGS16 mRNA |
CTD |
PMID:32741897 |
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NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
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G |
Rhof |
ras homolog family member F, filopodia associated |
increases expression |
EXP |
Fenofibrate results in increased expression of RHOF mRNA |
CTD |
PMID:32741897 |
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NCBI chr12:33,422,375...33,446,689
Ensembl chr12:33,431,280...33,446,703
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G |
Rlf |
RLF zinc finger |
increases expression |
EXP |
Fenofibrate results in increased expression of RLF mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:134,711,612...134,767,274
Ensembl chr 5:134,711,619...134,767,257
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G |
Rnd1 |
Rho family GTPase 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RND1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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G |
Rnd3 |
Rho family GTPase 3 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RND3 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
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G |
Rnf125 |
ring finger protein 125 |
increases expression |
ISO |
Fenofibrate results in increased expression of RNF125 mRNA |
CTD |
PMID:21318169 |
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NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983
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G |
Rnf14 |
ring finger protein 14 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of RNF14 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of RNF14 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr18:30,131,627...30,155,686
Ensembl chr18:30,131,691...30,155,685
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G |
Rnf144b |
ring finger protein 144B |
decreases expression multiple interactions |
ISO |
Fenofibrate results in decreased expression of RNF144B mRNA PPARA protein affects the reaction [Fenofibrate results in decreased expression of RNF144B mRNA] |
CTD |
PMID:21318169 |
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NCBI chr17:17,431,271...17,580,687
Ensembl chr17:17,432,786...17,562,760
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G |
Rnf19a |
ring finger protein 19A, RBR E3 ubiquitin protein ligase |
increases expression |
ISO |
Fenofibrate results in increased expression of RNF19A mRNA |
CTD |
PMID:21318169 |
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NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
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G |
Ro60 |
Ro60, Y RNA binding protein |
decreases expression |
ISO |
Fenofibrate results in decreased expression of RO60 mRNA |
CTD |
PMID:25596134 |
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NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
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G |
Rsrc2 |
arginine and serine rich coiled-coil 2 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of RSRC2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:32,839,840...32,859,820
Ensembl chr12:32,839,809...32,859,799
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G |
RT1-CE16 |
RT1 class I, locus CE16 |
affects response to substance |
ISO |
HLA-A gene polymorphism affects the susceptibility to Fenofibrate |
CTD |
PMID:28043905 |
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NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
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G |
RT1-Db1 |
RT1 class II, locus Db1 |
decreases expression |
ISO |
Fenofibrate results in decreased expression of H2-EB1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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G |
Rxra |
retinoid X receptor alpha |
decreases expression affects expression |
ISO EXP |
Fenofibrate results in decreased expression of RXRA mRNA Fenofibrate affects the expression of RXRA mRNA |
CTD |
PMID:25596134 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
S100a10 |
S100 calcium binding protein A10 |
increases expression |
ISO |
Fenofibrate results in increased expression of S100A10 mRNA |
CTD |
PMID:11798191 |
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NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
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G |
Sars1 |
seryl-tRNA synthetase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SARS1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
increases expression |
EXP |
Fenofibrate results in increased expression of SAT1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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G |
Scamp1 |
secretory carrier membrane protein 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SCAMP1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673
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G |
Scarb1 |
scavenger receptor class B, member 1 |
multiple interactions increases expression decreases activity |
ISO |
[Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein Fenofibrate results in increased expression of SCARB1 protein Fenofibrate inhibits the reaction [SCARB1 protein results in increased export of Cholesterol, HDL]; Fenofibrate inhibits the reaction [SCARB1 protein results in increased uptake of cholesteryl oleyl ether] Fenofibrate results in decreased activity of SCARB1 protein |
CTD |
PMID:16816107 PMID:17533223 |
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions affects expression increases expression |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA Fenofibrate affects the expression of SCD mRNA Fenofibrate results in increased expression of SCD1 mRNA NR1H2 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; NR1H3 gene mutant form affects the reaction [Fenofibrate results in increased expression of SCD1 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD1 mRNA] |
CTD |
PMID:23063693 PMID:24534255 PMID:27665778 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SCD mRNA; Fenofibrate results in increased expression of SCD2 mRNA NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SCD2 mRNA] |
CTD |
PMID:17118139 PMID:23063693 |
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NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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G |
Scly |
selenocysteine lyase |
affects expression |
EXP |
Fenofibrate affects the expression of SCLY mRNA |
CTD |
PMID:20801182 |
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NCBI chr 9:91,890,269...91,910,947
Ensembl chr 9:91,890,306...91,910,941
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G |
Sdhb |
succinate dehydrogenase complex iron sulfur subunit B |
increases expression |
ISO |
Fenofibrate results in increased expression of SDHB protein |
CTD |
PMID:24752549 |
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NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
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G |
Sec63 |
SEC63 homolog, protein translocation regulator |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SEC63 mRNA [PPARA protein affects the susceptibility to Fenofibrate] which affects the expression of SEC63 mRNA |
CTD |
PMID:21318169 |
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NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055
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G |
Sele |
selectin E |
multiple interactions |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA]]; Fenofibrate inhibits the reaction [ALB protein modified form results in increased expression of SELE mRNA] |
CTD |
PMID:20580385 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Sema6b |
semaphorin 6B |
multiple interactions decreases expression |
ISO |
alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B mRNA]; alitretinoin promotes the reaction [Fenofibrate results in decreased expression of SEMA6B protein] Fenofibrate results in decreased expression of SEMA6B mRNA; Fenofibrate results in decreased expression of SEMA6B protein |
CTD |
PMID:16525649 |
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NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
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G |
Senp2 |
SUMO specific peptidase 2 |
increases expression multiple interactions |
ISO |
Fenofibrate results in increased expression of SENP2 mRNA PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA] |
CTD |
PMID:21318169 |
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NCBI chr11:78,981,429...79,018,274
Ensembl chr11:78,981,432...79,018,238
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G |
Serpina3n |
serpin family A member 3N |
affects expression |
EXP |
Fenofibrate affects the expression of SERPINA3N mRNA |
CTD |
PMID:20801182 |
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NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions affects expression |
ISO EXP |
Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD4 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]] [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA Fenofibrate affects the expression of SERPINE1 mRNA Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]; Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein inhibits the reaction [Fenofibrate inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:18253720 PMID:19593819 PMID:20801182 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sertad1 |
SERTA domain containing 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SERTAD1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
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G |
Sesn1 |
sestrin 1 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SESN1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
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G |
Sgk2 |
serum/glucocorticoid regulated kinase 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SGK2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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G |
Sh3bgrl2 |
SH3 domain binding glutamate-rich protein like 2 |
increases expression |
ISO |
Fenofibrate results in increased expression of SH3BGRL2 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 8:84,461,019...84,553,124
Ensembl chr 8:84,461,121...84,551,564
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G |
Sh3tc1 |
SH3 domain and tetratricopeptide repeats 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SH3TC1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr14:75,005,691...75,050,001
Ensembl chr14:75,016,875...75,049,995
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G |
Siah2 |
siah E3 ubiquitin protein ligase 2 |
affects expression |
EXP |
Fenofibrate affects the expression of SIAH2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
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G |
Sik1 |
salt-inducible kinase 1 |
increases expression decreases expression |
ISO EXP |
Fenofibrate results in increased expression of SIK1 mRNA Fenofibrate results in decreased expression of SIK1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
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G |
Sirt1 |
sirtuin 1 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein]; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein]; zinc protoporphyrin inhibits the reaction [Fenofibrate results in increased expression of SIRT1 protein] |
CTD |
PMID:32730863 PMID:34520103 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Siva1 |
SIVA1, apoptosis-inducing factor |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SIVA1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
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G |
Slc10a1 |
solute carrier family 10 member 1 |
decreases expression |
ISO EXP |
Fenofibrate results in decreased expression of SLC10A1 mRNA |
CTD |
PMID:25572481 PMID:27765674 |
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NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
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G |
Slc16a13 |
solute carrier family 16, member 13 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC16A13 mRNA |
CTD |
PMID:25572481 |
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NCBI chr10:54,925,973...54,937,860
Ensembl chr10:54,926,760...54,937,788
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Slc16a6 |
solute carrier family 16, member 6 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC16A6 mRNA |
CTD |
PMID:25596134 |
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NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779
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G |
Slc1a7 |
solute carrier family 1 member 7 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC1A7 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134
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G |
Slc22a5 |
solute carrier family 22 member 5 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC22A5 mRNA |
CTD |
PMID:27665778 PMID:32741897 |
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NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
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G |
Slc25a20 |
solute carrier family 25 member 20 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of SLC25A20 mRNA |
CTD |
PMID:16707586 PMID:25572481 PMID:25596134 |
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NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a30 |
solute carrier family 25, member 30 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC25A30 mRNA |
CTD |
PMID:32741897 |
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NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
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G |
Slc25a34 |
solute carrier family 25, member 34 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC25A34 mRNA |
CTD |
PMID:25572481 |
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NCBI chr 5:153,932,081...153,936,854
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G |
Slc25a4 |
solute carrier family 25 member 4 |
decreases expression |
EXP |
Fenofibrate results in decreased expression of SLC25A4 protein |
CTD |
PMID:20118634 |
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NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
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G |
Slc27a1 |
solute carrier family 27 member 1 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC27A1 mRNA |
CTD |
PMID:11798191 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Slc27a2 |
solute carrier family 27 member 2 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of SLC27A2 mRNA |
CTD |
PMID:17118139 PMID:25572481 PMID:27665778 PMID:32741897 PMID:32741898 |
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NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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G |
Slc27a4 |
solute carrier family 27 member 4 |
multiple interactions increases expression |
ISO |
PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 mRNA]; PPARA gene mutant form inhibits the reaction [Fenofibrate results in increased expression of SLC27A4 protein] Fenofibrate results in increased expression of SLC27A4 mRNA; Fenofibrate results in increased expression of SLC27A4 protein PPARA protein promotes the reaction [Fenofibrate results in increased expression of SLC27A4 protein] |
CTD |
PMID:24752549 |
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NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
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G |
Slc34a2 |
solute carrier family 34 member 2 |
increases expression |
EXP |
Fenofibrate results in increased expression of SLC34A2 mRNA |
CTD |
PMID:32741897 |
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NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
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G |
Slc3a2 |
solute carrier family 3 member 2 |
increases expression |
ISO EXP |
Fenofibrate results in increased expression of SLC3A2 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc6a9 |
solute carrier family 6 member 9 |
decreases expression increases expression |
EXP ISO |
Fenofibrate results in decreased expression of SLC6A9 mRNA Fenofibrate results in increased expression of SLC6A9 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
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G |
Slc7a1 |
solute carrier family 7 member 1 |
increases expression |
EXP ISO |
Fenofibrate results in increased expression of SLC7A1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849
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G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
Fenofibrate results in increased expression of SLC7A5 mRNA |
CTD |
PMID:25596134 |
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NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
decreases expression |
ISO EXP |
Fenofibrate results in decreased expression of SLCO2B1 mRNA |
CTD |
PMID:25596134 |
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NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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G |
Smad3 |
SMAD family member 3 |
multiple interactions |
ISO |
Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]; NR0B2 protein promotes the reaction [Fenofibrate inhibits the reaction [SMAD3 protein results in increased expression of SERPINE1 mRNA]] |
CTD |
PMID:19593819 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
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