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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyfluthrin
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Accession:CHEBI:4034 term browser browse the term
Definition:A carboxylic ester obtained by formal condensation between 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid and (4-fluoro-3-phenoxyphenyl)(hydroxy)acetonitrile.
Synonyms:exact_synonym: cyano(4-fluoro-3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
 related_synonym: (R,S)-alpha-Cyano-4-fluoro-3-phenoxybenzyl-(1R,S)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate;   Formula=C22H18Cl2FNO3;   InChI=1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3;   InChIKey=QQODLKZGRKWIFG-UHFFFAOYSA-N;   SMILES=CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)c1ccc(F)c(Oc2ccccc2)c1
 xref: CAS:68359-37-5;   Drug_Central:4407;   KEGG:C10982;   KEGG:D07761
 xref_mesh: MESH:C052570
 xref: PMID:17912691;   PMID:18383791;   PPDB:192;   Patent:DE2709264;   Patent:US4218469;   Patent:US4287208;   Reaxys:2788149


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cyfluthrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP cyfluthrin results in decreased activity of ACHE protein CTD PMID:26604153 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in increased expression of AKT1 mRNA] CTD PMID:31330490 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610 		JBrowse link
G Alb albumin decreases expression
multiple interactions 		EXP cyfluthrin results in decreased expression of ALB protein
basil oil inhibits the reaction [cyfluthrin results in decreased expression of ALB protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased expression of ALB protein] 		CTD PMID:35126122 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865 		JBrowse link
G Aox1 aldehyde oxidase 1 multiple interactions
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in increased expression of AOX1 mRNA] CTD PMID:31330490 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO cyfluthrin results in increased expression of APAF1 mRNA CTD PMID:31330490 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772 		JBrowse link
G Ar androgen receptor decreases activity
multiple interactions 		ISO cyfluthrin results in decreased activity of AR protein
cyfluthrin binds to and results in increased activity of AR protein; Dihydrotestosterone inhibits the reaction [cyfluthrin results in increased activity of AR protein] 		CTD PMID:15064155 PMID:20410157 PMID:33049310 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467 		JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP cyfluthrin results in increased expression of ATF4 mRNA; cyfluthrin results in increased expression of ATF4 protein CTD PMID:36548566 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:113,684,681...113,686,739 		JBrowse link
G Atox1 antioxidant 1 copper chaperone decreases expression ISO cyfluthrin results in decreased expression of ATOX1 mRNA CTD PMID:31330490 NCBI chr10:40,065,525...40,080,627
Ensembl chr10:40,065,527...40,080,585 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		ISO cyfluthrin results in increased expression of BAX mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of BAX mRNA] 		CTD PMID:31330490 PMID:32028016 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO cyfluthrin results in increased expression of BCL2 mRNA CTD PMID:31330490 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase increases expression ISO cyfluthrin results in increased expression of BCR protein CTD PMID:16790487 NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP cyfluthrin results in increased expression of BDNF mRNA CTD PMID:16166269 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:116,619,633...116,670,657 		JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in increased expression of BNIP3 mRNA] CTD PMID:31330490 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO cyfluthrin results in increased expression of CAMK2A mRNA CTD PMID:32028016 NCBI chr18:56,648,779...56,711,505
Ensembl chr18:56,649,025...56,711,504 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta increases expression ISO cyfluthrin results in increased expression of CAMK2B mRNA CTD PMID:32028016 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:85,059,191...85,148,485 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions 		ISO cyfluthrin results in increased expression of CASP3 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of CASP3 mRNA] 		CTD PMID:31330490 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase decreases activity
decreases expression
affects binding
multiple interactions 		ISO
EXP 		cyfluthrin results in decreased activity of CAT protein
cyfluthrin results in decreased expression of CAT mRNA
cyfluthrin binds to CAT protein
cyfluthrin results in decreased expression of CAT protein
basil oil inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]
[Melatonin co-treated with cyfluthrin] results in increased activity of CAT protein; Melatonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; N-acetylserotonin inhibits the reaction [cyfluthrin results in decreased activity of CAT protein] 		CTD PMID:19961921 PMID:23595963 PMID:26604153 PMID:31330490 PMID:32278787 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in increased expression of CCL5 mRNA] CTD PMID:31330490 NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,738,651...68,824,884 		JBrowse link
G Ces2e carboxylesterase 2E affects metabolic processing ISO CES2E protein affects the metabolism of cyfluthrin CTD PMID:15123619 NCBI chr19:157,447...172,822
Ensembl chr19:163,859...179,308 		JBrowse link
G Ces2h carboxylesterase 2H increases metabolic processing ISO CES2 protein results in increased metabolism of cyfluthrin CTD PMID:19249324 NCBI chr19:49,884,164...49,898,764
Ensembl chr19:49,884,164...49,898,752 		JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP cyfluthrin results in decreased expression of CHAT protein CTD PMID:26604153 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416 		JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO cyfluthrin results in increased expression of CLIP3 protein CTD PMID:16790487 NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:94,674,661...94,690,642 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in increased expression of CYBB mRNA] CTD PMID:31330490 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065 		JBrowse link
G Cygb cytoglobin decreases expression ISO cyfluthrin results in decreased expression of CYGB mRNA CTD PMID:31330490 NCBI chr10:102,376,506...102,386,272
Ensembl chr10:102,376,507...102,386,272 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity EXP cyfluthrin results in increased activity of CYP2E1 protein CTD PMID:23639246 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO cyfluthrin results in increased expression of CYP3A4 mRNA CTD PMID:19249324 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP cyfluthrin results in increased expression of DDIT3 mRNA; cyfluthrin results in increased expression of DDIT3 protein CTD PMID:36548566 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509 		JBrowse link
G Duox1 dual oxidase 1 increases expression ISO cyfluthrin results in increased expression of DUOX1 mRNA CTD PMID:31330490 NCBI chr 3:129,714,125...129,749,186
Ensembl chr 3:129,714,149...129,749,187 		JBrowse link
G Duox2 dual oxidase 2 increases expression ISO cyfluthrin results in increased expression of DUOX2 mRNA CTD PMID:31330490 NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:129,680,546...129,699,203 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression 		EXP cyfluthrin results in increased phosphorylation of EIF2AK3 protein
cyfluthrin results in increased expression of EIF2AK3 mRNA 		CTD PMID:36548566 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:104,363,833...104,425,268 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases expression
increases phosphorylation 		EXP cyfluthrin results in increased expression of EIF2S1 mRNA
cyfluthrin results in increased phosphorylation of EIF2S1 protein 		CTD PMID:36548566 NCBI chr 6:103,405,880...103,430,549
Ensembl chr 6:103,405,788...103,431,649 		JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO cyfluthrin results in decreased expression of EPHX2 mRNA CTD PMID:31330490 NCBI chr15:44,465,447...44,503,157
Ensembl chr15:44,465,448...44,503,160 		JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
decreases activity 		ISO
EXP 		cyfluthrin results in increased activity of ESR1 protein
cyfluthrin binds to and results in increased activity of ESR1 protein
cyfluthrin results in decreased activity of ESR1 protein 		CTD PMID:15064155 PMID:20410157 PMID:33049310 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 increases expression EXP cyfluthrin results in increased expression of FLT1 protein CTD PMID:36548566 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:12,333,430...12,504,750 		JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression ISO cyfluthrin results in decreased expression of FTH1 mRNA CTD PMID:31330490 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214 		JBrowse link
G Gap43 growth associated protein 43 increases expression ISO cyfluthrin results in increased expression of GAP43 mRNA CTD PMID:32028016 NCBI chr11:71,882,131...71,975,799
Ensembl chr11:71,882,131...71,975,797 		JBrowse link
G Gla galactosidase, alpha decreases expression ISO cyfluthrin results in decreased expression of GLA mRNA CTD PMID:31330490 NCBI chr  X:102,062,497...102,073,915
Ensembl chr  X:102,056,718...102,073,915 		JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity
multiple interactions 		EXP cyfluthrin affects the activity of GPT protein
basil oil affects the reaction [cyfluthrin affects the activity of GPT protein]; Oils, Volatile affects the reaction [cyfluthrin affects the activity of GPT protein] 		CTD PMID:35126122 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO cyfluthrin results in decreased expression of GPX1 mRNA CTD PMID:31330490 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581 		JBrowse link
G Gpx2 glutathione peroxidase 2 decreases expression ISO cyfluthrin results in decreased expression of GPX2 mRNA CTD PMID:31330490 NCBI chr 6:101,226,745...101,230,033
Ensembl chr 6:101,226,745...101,230,862 		JBrowse link
G Gpx3 glutathione peroxidase 3 decreases expression ISO cyfluthrin results in decreased expression of GPX3 mRNA CTD PMID:31330490 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,529,448...39,537,405 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases expression
decreases activity 		EXP
ISO 		basil oil inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]; Oils, Volatile inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]
cyfluthrin results in decreased expression of GSR mRNA 		CTD PMID:23595963 PMID:31330490 PMID:35126122 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO cyfluthrin results in decreased expression of GSTZ1 mRNA CTD PMID:31330490 NCBI chr 6:112,525,576...112,536,228
Ensembl chr 6:112,525,377...112,536,233 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression ISO cyfluthrin results in increased expression of HSP90AA1 mRNA CTD PMID:31330490 NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:135,523,616...135,528,499 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions 		ISO cyfluthrin results in increased expression of HSPA1A mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of HSPA1A mRNA] 		CTD PMID:31330490 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,855,780...3,877,979 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP cyfluthrin results in increased expression of HSPA5 mRNA; cyfluthrin results in increased expression of HSPA5 protein CTD PMID:36548566 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:38,453,041...38,458,790 		JBrowse link
G Hydin Hydin, axonemal central pair apparatus protein decreases expression ISO cyfluthrin results in decreased expression of HYDIN protein CTD PMID:16790487 NCBI chr19:38,236,996...38,583,271
Ensembl chr19:55,146,466...55,492,660 		JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP 		cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]
[Dichlorvos co-treated with cyfluthrin co-treated with Xylenes co-treated with Kerosene] affects the expression of IFNG protein 		CTD PMID:12755381 PMID:12838427 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein] CTD PMID:12755381 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions 		ISO
EXP 		cyfluthrin results in increased expression of IL6 protein
basil oil inhibits the reaction [cyfluthrin results in increased expression of IL6 mRNA]; Oils, Volatile inhibits the reaction [cyfluthrin results in increased expression of IL6 mRNA]
cyfluthrin results in increased expression of IL6 mRNA; cyfluthrin results in increased expression of IL6 protein 		CTD PMID:16790487 PMID:35126122 PMID:36515635 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha increases expression EXP
ISO 		cyfluthrin results in increased expression of MAP1LC3A mRNA CTD PMID:36515635 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:164,243,093...164,244,850 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression ISO cyfluthrin results in increased expression of MAPK1 protein CTD PMID:16790487 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO cyfluthrin results in increased expression of MAPK3 protein CTD PMID:16790487 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mtor mechanistic target of rapamycin kinase increases expression
decreases expression 		ISO
EXP 		cyfluthrin results in increased expression of MTOR mRNA; cyfluthrin results in increased expression of MTOR protein
cyfluthrin results in decreased expression of MTOR protein modified form 		CTD PMID:36515635 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435 		JBrowse link
G Nefh neurofilament heavy chain increases expression ISO cyfluthrin results in increased expression of NEFH mRNA CTD PMID:32028016 NCBI chr14:84,044,428...84,054,413
Ensembl chr14:84,044,023...84,054,417 		JBrowse link
G Nefl neurofilament light chain decreases expression ISO cyfluthrin results in decreased expression of NEFL mRNA CTD PMID:32028016 NCBI chr15:46,477,330...46,481,203
Ensembl chr15:46,458,204...46,482,515 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions 		ISO cyfluthrin results in increased expression of NFE2L2 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of NFE2L2 mRNA] 		CTD PMID:31330490 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO cyfluthrin results in increased expression of NFKB1 mRNA CTD PMID:31330490 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions 		ISO cyfluthrin results in increased expression of NOS2 mRNA
Melatonin inhibits the reaction [cyfluthrin results in increased expression of NOS2 mRNA] 		CTD PMID:31330490 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
decreases activity
increases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein]; Melatonin inhibits the reaction [cyfluthrin results in increased expression of NQO1 mRNA]; Silybin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein] CTD PMID:31330490 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO cyfluthrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity
multiple interactions 		EXP
ISO 		cyfluthrin results in increased activity of NR1I2 protein
cyfluthrin results in increased activity of NR1I2 protein; cyfluthrin results in increased activity of NR1I2 protein polymorphism
cyfluthrin binds to and results in increased activity of NR1I2 protein 		CTD PMID:19249324 PMID:21115097 PMID:22206814 PMID:33049310 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP cyfluthrin results in decreased expression of PCNA protein CTD PMID:36548566 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901 		JBrowse link
G Pgf placental growth factor decreases expression EXP cyfluthrin results in decreased expression of PGF protein CTD PMID:36548566 NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:110,547,153...110,557,747 		JBrowse link
G Pgr progesterone receptor affects binding ISO cyfluthrin binds to PGR protein CTD PMID:32278787 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271 		JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 increases expression ISO cyfluthrin results in increased expression of PIK3C3 mRNA CTD PMID:32028016 NCBI chr18:22,119,677...22,203,546
Ensembl chr18:22,119,792...22,203,539 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO cyfluthrin binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta increases expression ISO cyfluthrin results in increased expression of PPP2R3B protein CTD PMID:16790487 NCBI chr14:103,496...110,739
Ensembl chr14:103,374...110,739 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO cyfluthrin results in decreased expression of PRDX2 mRNA CTD PMID:31330490 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006 		JBrowse link
G Prdx4 peroxiredoxin 4 decreases expression ISO cyfluthrin results in decreased expression of PRDX4 mRNA CTD PMID:31330490 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:43,876,417...43,893,812 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO cyfluthrin results in decreased expression of PRDX5 mRNA CTD PMID:31330490 NCBI chr 1:213,529,042...213,532,787
Ensembl chr 1:213,529,035...213,533,020 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases expression ISO cyfluthrin results in decreased expression of PRKAA1 mRNA CTD PMID:36515635 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases expression EXP cyfluthrin results in decreased expression of PRKAA2 mRNA CTD PMID:36515635 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO cyfluthrin results in decreased expression of PTGS1 mRNA CTD PMID:31330490 NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:39,981,415...40,002,990 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO cyfluthrin results in increased expression of PTGS2 mRNA CTD PMID:31330490 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases expression
increases expression 		EXP
ISO 		cyfluthrin results in decreased expression of RPS6KB1 protein modified form
cyfluthrin results in increased expression of RPS6KB1 mRNA; cyfluthrin results in increased expression of RPS6KB1 protein 		CTD PMID:36515635 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,815,614...71,865,238 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 multiple interactions EXP [Dichlorvos co-treated with cyfluthrin co-treated with Xylenes co-treated with Kerosene] results in increased expression of SCGB1A1 protein CTD PMID:12838427 NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:215,406,138...215,409,686 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity 		EXP cyfluthrin affects the reaction [SCN10A protein results in increased transport of Sodium]
cyfluthrin affects the activity of SCN10A protein 		CTD PMID:16051293 PMID:19766671 NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:128,228,424...128,340,298 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:95,481,298...95,491,197 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 multiple interactions EXP cyfluthrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:70,710,954...70,845,279 		JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 multiple interactions EXP cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:70,554,496...70,666,198
Ensembl chr 3:70,556,224...70,666,198 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 multiple interactions EXP cyfluthrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:49,527,577...49,550,018 		JBrowse link
G Slc6a14 solute carrier family 6 member 14 decreases expression ISO cyfluthrin results in decreased expression of SLC6A14 protein CTD PMID:16790487 NCBI chr  X:117,109,063...117,169,522
Ensembl chr  X:117,108,947...117,169,828 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO cyfluthrin results in decreased expression of SOD2 mRNA CTD PMID:31330490 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
increases expression 		ISO
EXP 		Melatonin inhibits the reaction [cyfluthrin results in increased expression of SQSTM1 mRNA]
cyfluthrin results in decreased expression of SQSTM1 mRNA; cyfluthrin results in decreased expression of SQSTM1 protein 		CTD PMID:31330490 PMID:36515635 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 decreases expression ISO cyfluthrin results in decreased expression of STAT6 protein CTD PMID:12755381 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 increases expression ISO
EXP 		cyfluthrin results in increased expression of STING1 mRNA; cyfluthrin results in increased expression of STING1 protein CTD PMID:36515635 NCBI chr18:27,606,196...27,612,544
Ensembl chr18:27,606,196...27,611,947 		JBrowse link
G Syn1 synapsin I decreases expression ISO cyfluthrin results in decreased expression of SYN1 mRNA CTD PMID:32028016 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:3,725,714...3,780,938 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO cyfluthrin binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression ISO cyfluthrin results in decreased expression of TJP1 mRNA CTD PMID:36167171 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions 		ISO
EXP 		cyfluthrin results in increased expression of TNF mRNA
basil oil inhibits the reaction [cyfluthrin results in increased expression of TNF mRNA]; Oils, Volatile inhibits the reaction [cyfluthrin results in increased expression of TNF mRNA]
cyfluthrin results in increased expression of TNF mRNA; cyfluthrin results in increased expression of TNF protein 		CTD PMID:31330490 PMID:35126122 PMID:36515635 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO cyfluthrin results in increased expression of TP53 mRNA CTD PMID:31330490 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Trappc6a trafficking protein particle complex subunit 6A multiple interactions
decreases expression 		ISO Melatonin inhibits the reaction [cyfluthrin results in decreased expression of TRAPPC6A mRNA] CTD PMID:31330490 NCBI chr 1:88,286,533...88,293,493
Ensembl chr 1:88,286,362...88,293,493 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression ISO cyfluthrin results in decreased expression of TXNRD1 mRNA CTD PMID:31330490 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP cyfluthrin results in decreased expression of VEGFA mRNA; cyfluthrin results in decreased expression of VEGFA protein CTD PMID:36548566 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Wnt3a Wnt family member 3A increases expression ISO cyfluthrin results in increased expression of WNT3A mRNA CTD PMID:32028016 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO cyfluthrin results in increased expression of WNT5A mRNA CTD PMID:32028016 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,703,665...3,724,860 		JBrowse link
G Wnt7a Wnt family member 7A increases expression ISO cyfluthrin results in increased expression of WNT7A mRNA CTD PMID:32028016 NCBI chr 4:125,420,276...125,466,149
Ensembl chr 4:125,420,276...125,466,149 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        agrochemical 17119
          cyfluthrin 98
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      monocarboxylic acid 18309
                                        cyclopropanecarboxylic acid 2254
                                          3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid 2114
                                            cyfluthrin 98
paths to the root