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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fenpropathrin
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Accession:CHEBI:39353 term browser browse the term
Definition:A cyclopropanecarboxylate ester obtained by formal condensation between 2,2,3,3-tetramethylcyclopropanecarboxylic acid and cyano(3-phenoxyphenyl)methanol.
Synonyms:exact_synonym: cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate
 related_synonym: 2,2,3,3-Tetramethylcyclopropanecarboxylic acid cyano(3-phenoxyphenyl)methyl ester;   Formula=C22H23NO3;   InChI=1S/C22H23NO3/c1-21(2)19(22(21,3)4)20(24)26-18(14-23)15-9-8-12-17(13-15)25-16-10-6-5-7-11-16/h5-13,18-19H,1-4H3;   InChIKey=XQUXKZZNEFRCAW-UHFFFAOYSA-N;   Meothrin;   SMILES=CC1(C)C(C(=O)OC(C#N)c2cccc(Oc3ccccc3)c2)C1(C)C
 xref: Beilstein:2673776;   CAS:39515-41-8;   KEGG:C18411
 xref_mesh: MESH:C044267
 xref: PMID:10552511;   PMID:12952428;   PMID:18808096;   PMID:20640937;   PMID:21052987;   PMID:21181490;   PMID:21370394;   PMID:21381771;   PMID:21404693;   PMID:21503692;   PMID:21727000;   PMID:21785877;   PMID:8571384;   PPDB:306;   Patent:DE2231312;   Patent:US3835176;   Reaxys:2673776



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fenpropathrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp1 caspase 1 increases expression
multiple interactions
EXP fenpropathrin results in increased expression of CASP1 mRNA
Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP1 mRNA]
CTD PMID:38369055 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp2 caspase 2 increases expression
multiple interactions
EXP fenpropathrin results in increased expression of CASP2 mRNA
Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP2 mRNA]
CTD PMID:38369055 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
EXP Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP3 protein]
fenpropathrin results in increased expression of CASP3 mRNA; fenpropathrin results in increased expression of CASP3 protein
CTD PMID:38369055 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
EXP Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP7 mRNA] CTD PMID:38369055 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP8 mRNA] CTD PMID:38369055 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of CASP9 mRNA] CTD PMID:38369055 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression EXP fenpropathrin results in increased expression of CAT protein CTD PMID:32949931 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
EXP fenpropathrin results in decreased activity of CYP1A1 protein
fenpropathrin results in increased expression of CYP1A1 mRNA
CTD PMID:20009351 PMID:32949931 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of FAS mRNA] CTD PMID:38369055 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of FASL mRNA] CTD PMID:38369055 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gsdmd gasdermin D decreases expression
multiple interactions
EXP fenpropathrin results in decreased expression of GSDMD mRNA
Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in decreased expression of GSDMD mRNA]
CTD PMID:38369055 NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
JBrowse link
G Gzma granzyme A multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of GZMA mRNA] CTD PMID:38369055 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
EXP Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of IL1B mRNA] CTD PMID:38369055 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions
increases expression
EXP Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of NLRP3 mRNA] CTD PMID:38369055 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
EXP Chitosan promotes the reaction [Curcumin inhibits the reaction [fenpropathrin results in increased expression of RELA mRNA]]; Curcumin inhibits the reaction [fenpropathrin results in increased expression of RELA mRNA] CTD PMID:38369055 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 multiple interactions
affects activity
EXP fenpropathrin affects the reaction [SCN10A protein results in increased transport of Sodium]
fenpropathrin affects the activity of SCN10A protein
CTD PMID:16051293 PMID:19766671 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP fenpropathrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 multiple interactions EXP fenpropathrin affects the reaction [[SCN2A protein binds to SCN1B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 multiple interactions EXP fenpropathrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 multiple interactions EXP fenpropathrin affects the reaction [[SCN3A protein binds to SCN3B protein] which results in increased transport of Sodium] CTD PMID:18538810 NCBI chr 8:40,630,372...40,652,869
Ensembl chr 8:40,630,455...40,652,868
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of TNF protein] CTD PMID:38369055 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
EXP fenpropathrin results in increased expression of TP53 mRNA
Curcumin inhibits the reaction [fenpropathrin results in increased expression of TP53 mRNA]
CTD PMID:38369055 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vim vimentin multiple interactions
increases expression
EXP Curcumin inhibits the reaction [fenpropathrin results in increased expression of VIM protein] CTD PMID:38369055 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link

Term paths to the root
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  CHEBI ontology 19878
    role 19848
      application 19690
        agrochemical 16865
          fenpropathrin 23
Path 2
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  CHEBI ontology 19878
    subatomic particle 19876
      composite particle 19876
        hadron 19876
          baryon 19876
            nucleon 19876
              atomic nucleus 19876
                atom 19876
                  main group element atom 19815
                    p-block element atom 19815
                      carbon group element atom 19755
                        carbon atom 19752
                          organic molecular entity 19752
                            heteroorganic entity 19509
                              organochalcogen compound 19270
                                organooxygen compound 19186
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18001
                                        cyclopropanecarboxylic acid 2232
                                          2,2,3,3-tetramethylcyclopropanecarboxylic acid 23
                                            fenpropathrin 23
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