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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:spinosyn
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Accession:CHEBI:39207 term browser browse the term
Definition:A family of macrolide natural products produced by the soil microorganism Saccharopolyspora spinosa.



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spinosad term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO spinosad inhibits the reaction [ABCB1 protein results in increased transport of calcein AM]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of Ivermectin]
spinosad results in decreased activity of ABCB1 protein
CTD PMID:21321059 PMID:37985955 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit decreases response to substance ISO CHRNA7 protein mutant form results in decreased susceptibility to spinosad CTD PMID:23016960 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            prokaryotic metabolite 18583
              bacterial metabolite 18583
                spinosyn 2
                  spinosyn A + 2
                  spinosyn B 0
                  spinosyn D + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbohydrates and carbohydrate derivatives 15285
                                    carbohydrate 15285
                                      carbohydrate derivative 14300
                                        glycosyl compound 13062
                                          glycoside 11830
                                            spinosyn 2
                                              spinosyn A + 2
                                              spinosyn B 0
                                              spinosyn D + 2
paths to the root