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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:temephos
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Accession:CHEBI:38954 term browser browse the term
Definition:An organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group.
Synonyms:related_synonym: Abate;   O,O'-(thiodi-4,1-phenylene) bis(O,O-dimethyl phosphorothioate);   O,O,O',O'-tetramethyl O,O'-(sulfanediyldi-4,1-phenylene) bis(phosphorothioate);   O,O,O',O'-tetramethyl O,O'-(sulfanediyldibenzene-4,1-diyl) bis(phosphorothioate);   O,O,O',O'-tetramethyl O,O'-(sulfanediyldibenzene-4,1-diyl) bis(thiophosphate);   O,O,O',O'-tetramethyl O,O'-thiodi-p-phenylene bis(phosphorothioate);   O,O,O',O'-tetramethyl O,O'-thiodi-p-phenylene diphosphorothioate;   Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester;   temefos
 xref: Beilstein:1896901;   CAS:3383-96-8
 xref_mesh: MESH:D000002
 xref: PPDB:618;   Pesticides:temephos;   VSDB:618;   kegg.compound:C18809;   kegg.drug:D06062;   lincs.smallmolecule:LSM-3148;   pubmed:27180726;   pubmed:27419140
 chemrof_formula: C16H20O6P2S3
 chemrof_smiles: COP(=S)(OC)Oc1ccc(Sc2ccc(OP(=S)(OC)OC)cc2)cc1
 chemrof_inchi: InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3
 chemrof_inchikey: WWJZWCUNLNYYAU-UHFFFAOYSA-N
 cyclic_relationship: has_functional_parent CHEBI:38957


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temephos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP Temefos results in decreased activity of ACHE protein CTD PMID:34382084 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Temefos results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Temefos inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      application 20572
        agrochemical 16228
          temephos 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    p-block element atom 20796
                      pnictogen 19695
                        phosphorus atom 14760
                          phosphorus molecular entity 14760
                            phosphorus oxoacids and derivatives 14745
                              phosphorus oxoacid derivative 14118
                                phosphoric acid derivative 13866
                                  phosphate 13865
                                    organic phosphate 13865
                                      organic thiophosphate 8677
                                        temephos 3
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