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G |
Ache |
acetylcholinesterase |
decreases activity |
EXP ISO |
phoxim metabolite results in decreased activity of ACHE protein; phoxim results in decreased activity of ACHE protein |
CTD |
PMID:15793557 PMID:33497710 PMID:33844597 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
phoxim inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] |
CTD |
PMID:33049310 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arl6ip5 |
ARF like GTPase 6 interacting protein 5 |
affects expression |
ISO |
phoxim affects the expression of ARL6IP5 protein |
CTD |
PMID:15799245 |
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NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
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G |
Bche |
butyrylcholinesterase |
decreases activity |
EXP |
phoxim metabolite results in decreased activity of BCHE protein |
CTD |
PMID:33497710 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
increases expression multiple interactions |
ISO |
phoxim results in increased expression of CEBPA protein Fulvestrant inhibits the reaction [phoxim results in increased expression of CEBPA protein] |
CTD |
PMID:33872936 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cldn4 |
claudin 4 |
decreases expression multiple interactions |
EXP |
phoxim results in decreased expression of CLDN4 mRNA Vitamin E inhibits the reaction [phoxim results in decreased expression of CLDN4 mRNA] |
CTD |
PMID:30003487 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression |
EXP |
phoxim results in increased expression of CYP2B1 mRNA |
CTD |
PMID:36356836 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions affects binding |
ISO |
phoxim binds to and results in increased activity of ESR1 protein phoxim binds to ESR1 protein |
CTD |
PMID:33049310 PMID:33872936 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Fas |
Fas cell surface death receptor |
increases expression multiple interactions |
ISO |
phoxim results in increased expression of FAS mRNA Fulvestrant inhibits the reaction [phoxim results in increased expression of FAS mRNA] |
CTD |
PMID:33872936 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Gpx2 |
glutathione peroxidase 2 |
increases expression multiple interactions |
EXP |
phoxim results in increased expression of GPX2 mRNA Vitamin E inhibits the reaction [phoxim results in increased expression of GPX2 mRNA] |
CTD |
PMID:30003487 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Il1b |
interleukin 1 beta |
decreases expression |
EXP |
phoxim results in decreased expression of IL1B mRNA |
CTD |
PMID:30003487 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
EXP |
phoxim results in decreased expression of IL6 mRNA Vitamin E inhibits the reaction [phoxim results in decreased expression of IL6 mRNA] |
CTD |
PMID:30003487 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Irs2 |
insulin receptor substrate 2 |
decreases expression |
EXP |
phoxim results in decreased expression of IRS2 mRNA |
CTD |
PMID:30090575 |
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NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Lpl |
lipoprotein lipase |
increases expression multiple interactions |
ISO |
phoxim results in increased expression of LPL mRNA Fulvestrant inhibits the reaction [phoxim results in increased expression of LPL mRNA] |
CTD |
PMID:33872936 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression |
EXP |
phoxim results in increased expression of NFE2L2 mRNA |
CTD |
PMID:30003487 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
phoxim binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:33049310 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Ocln |
occludin |
multiple interactions decreases expression |
EXP |
Vitamin E inhibits the reaction [phoxim results in decreased expression of OCLN mRNA] |
CTD |
PMID:30003487 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Plin1 |
perilipin 1 |
multiple interactions increases expression |
ISO |
Fulvestrant inhibits the reaction [phoxim results in increased expression of PLIN1 protein]; tolclofos-methyl inhibits the reaction [phoxim results in increased expression of PLIN1 protein] |
CTD |
PMID:33872936 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO |
phoxim binds to and results in increased activity of PPARG protein Fulvestrant inhibits the reaction [phoxim results in increased expression of PPARG protein]; phoxim binds to and results in increased activity of PPARG protein |
CTD |
PMID:33049310 PMID:33872936 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
phoxim binds to and results in decreased activity of THRA protein |
CTD |
PMID:33049310 |
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NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
EXP |
Vitamin E inhibits the reaction [phoxim results in increased expression of TNF protein] phoxim results in increased expression of TNF mRNA; phoxim results in increased expression of TNF protein |
CTD |
PMID:30003487 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tp53 |
tumor protein p53 |
affects activity |
ISO |
phoxim metabolite affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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