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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N-(hydroxymethyl)phthalimide
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Accession:CHEBI:38816 term browser browse the term
Definition:A primary alcohol comprising phthalimide carrying an N-hydroxymethyl substituent.
Synonyms:exact_synonym: 2-(hydroxymethyl)isoindole-1,3-dione
 related_synonym: Formula=C9H7NO3;   InChI=1S/C9H7NO3/c11-5-10-8(12)6-3-1-2-4-7(6)9(10)13/h1-4,11H,5H2;   InChIKey=MNSGOOCAMMSKGI-UHFFFAOYSA-N;   N-Hydroxymethylphthalimide;   Phthalimidomethanol;   Phthalimidomethyl alcohol;   SMILES=OCN1C(=O)c2ccccc2C1=O
 xref: CAS:118-29-6;   PMID:11376613;   PMID:13129307;   PMID:18272363;   PMID:19073064;   PMID:6644601;   Reaxys:140946


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phosmet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO
EXP		 Phosmet metabolite results in decreased activity of ACHE protein; Phosmet results in decreased activity of ACHE protein CTD PMID:30625376 PMID:33720374 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Il13 interleukin 13 increases expression ISO Phosmet results in increased expression of IL13 mRNA CTD PMID:22265773 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il17a interleukin 17A increases expression ISO Phosmet results in increased expression of IL17A mRNA CTD PMID:22265773 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Tnf tumor necrosis factor increases secretion ISO Phosmet results in increased secretion of TNF mRNA; Phosmet results in increased secretion of TNF protein CTD PMID:22265773 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Phosmet metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    chemical entity 19872
      molecular entity 19872
        polyatomic entity 19824
          heteroatomic molecular entity 19781
            hydroxides 19341
              organic hydroxy compound 18951
                alcohol 15716
                  primary alcohol 14665
                    N-(hydroxymethyl)phthalimide 5
                      phosmet 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            organic molecule 19700
                              organic cyclic compound 19490
                                organic heterocyclic compound 18868
                                  organic heteropolycyclic compound 18294
                                    organic heterobicyclic compound 17237
                                      benzopyrrole 9739
                                        isoindoles 1150
                                          phthalimides 1013
                                            phthalimide 553
                                              N-(hydroxymethyl)phthalimide 5
                                                phosmet 5
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