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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzenedicarboxamide
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Accession:CHEBI:38800 term browser browse the term
Synonyms:related_synonym: Formula=C8H8N2O2


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flubendiamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases activity
multiple interactions 		EXP flubendiamide results in decreased activity of CAT protein
alpha-Tocopherol affects the reaction [flubendiamide results in decreased activity of CAT protein] 		CTD PMID:27823922 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO flubendiamide promotes the reaction [Ryanodine binds to RYR1 protein] CTD PMID:30329129 NCBI chr 1:93,420,078...93,551,305
Ensembl chr 1:93,420,078...93,551,305 		JBrowse link
iohexol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen increases expression
multiple interactions 		EXP Iohexol results in increased expression of AGT protein
telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein] 		CTD PMID:19452295 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Iohexol results in increased expression of BAK1 mRNA CTD PMID:29705293 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		ISO
EXP 		Iohexol results in increased expression of BAX mRNA; Iohexol results in increased expression of BAX protein
Amlodipine inhibits the reaction [Iohexol results in increased expression of BAX protein]; cilnidipine inhibits the reaction [Iohexol results in increased expression of BAX protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of BAX protein] 		CTD PMID:29705293 PMID:36207783 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Iohexol results in increased expression of BBC3 mRNA CTD PMID:29705293 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO
EXP 		Iohexol results in decreased expression of BCL2 protein
Amlodipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; cilnidipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; Nifedipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein] 		CTD PMID:36207783 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Becn1 beclin 1 multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of BECN1 protein; Berberine promotes the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of BECN1 protein] CTD PMID:38705399 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,731,650...86,747,002 		JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of BNIP3 protein; Berberine promotes the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of BNIP3 protein] CTD PMID:38705399 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:203,137,778...203,154,962 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions ISO CAMK2G protein inhibits the reaction [Iohexol results in increased expression of PPIF protein]; CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]; cilnidipine inhibits the reaction [CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]] CTD PMID:36207783 NCBI chr15:3,504,017...3,563,050
Ensembl chr15:3,553,294...3,612,310 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of and results in increased cleavage of CASP1 protein; [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CASP1 mRNA; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of and results in increased cleavage of CASP1 protein]; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CASP1 mRNA] CTD PMID:38705399 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
increases activity 		EXP
ISO 		Amlodipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]]; cilnidipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; Iohexol promotes the reaction [Glycerol results in increased expression of CASP3 mRNA]; Nifedipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; Telmisartan inhibits the reaction [Iohexol results in increased activity of CASP3 protein]
Amlodipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]; cilnidipine inhibits the reaction [CAMK2G protein promotes the reaction [Iohexol results in increased cleavage of CASP3 protein]]; cilnidipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein]; Nifedipine inhibits the reaction [Iohexol results in increased cleavage of CASP3 protein] 		CTD PMID:19452295 PMID:26562095 PMID:36207783 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp9 caspase 9 increases expression ISO Iohexol results in increased expression of CASP9 mRNA; Iohexol results in increased expression of CASP9 protein CTD PMID:29705293 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions 		ISO Iohexol results in increased expression of CCL2 protein
[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CCL2 mRNA; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CCL2 mRNA] 		CTD PMID:34774977 PMID:38705399 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Cst3 cystatin C multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CST3 protein; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of CST3 protein] CTD PMID:38705399 NCBI chr 3:156,790,061...156,794,116
Ensembl chr 3:156,790,079...156,793,937 		JBrowse link
G Eng endoglin decreases expression ISO Iohexol results in decreased expression of ENG protein CTD PMID:29705293 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression ISO Iohexol results in increased expression of FABP3 mRNA CTD PMID:29705293 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of GCLM mRNA CTD PMID:29860548 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression
multiple interactions 		EXP Iohexol results in increased expression of HAVCR1 protein
Amlodipine inhibits the reaction [Iohexol results in increased expression of HAVCR1 protein]; cilnidipine inhibits the reaction [Iohexol results in increased expression of HAVCR1 protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of HAVCR1 protein] 		CTD PMID:36207783 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268 		JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO Iohexol results in increased secretion of HEXB protein CTD PMID:34774977 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions EXP
ISO 		[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMGB1 protein
[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of HMGB1 protein; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of HMGB1 protein] 		CTD PMID:29860548 PMID:38705399 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions 		ISO
EXP 		Iohexol results in increased expression of HMOX1 mRNA
[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of HMOX1 mRNA 		CTD PMID:29705293 PMID:29860548 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Iohexol results in decreased expression of IFI44 mRNA CTD PMID:29705293 NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Iohexol results in decreased expression of IFIH1 mRNA CTD PMID:29705293 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO 		Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of IL1B mRNA]
[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL1B mRNA; [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL1B protein; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL1B mRNA]; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL1B protein] 		CTD PMID:26562095 PMID:38705399 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL6 mRNA; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of IL6 mRNA] CTD PMID:38705399 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions
increases expression 		EXP Amlodipine inhibits the reaction [Iohexol results in increased expression of LCN2 protein]; cilnidipine inhibits the reaction [Iohexol results in increased expression of LCN2 protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of LCN2 protein] CTD PMID:36207783 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Iohexol results in increased expression of MAP3K1 mRNA CTD PMID:29705293 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO Iohexol results in decreased phosphorylation of MAPK1 protein CTD PMID:34774977 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO Iohexol results in increased expression of MAPK14 mRNA CTD PMID:29705293 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO Iohexol results in decreased phosphorylation of MAPK3 protein CTD PMID:34774977 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP
ISO 		[Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in increased expression of NLRP3 protein
[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of NLRP3 mRNA; [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of NLRP3 protein; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of NLRP3 mRNA]; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of NLRP3 protein] 		CTD PMID:29860548 PMID:38705399 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP [Drinking Water deficiency co-treated with Furosemide co-treated with Iohexol] results in decreased expression of NQO1 mRNA CTD PMID:29860548 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 decreases expression ISO Iohexol results in decreased expression of OAS3 mRNA CTD PMID:29705293 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Iohexol results in increased expression of PPARG mRNA CTD PMID:29705293 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104 		JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions
increases expression 		EXP
ISO 		Amlodipine inhibits the reaction [Iohexol results in increased expression of PPIF protein]; cilnidipine inhibits the reaction [Iohexol results in increased expression of PPIF protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of PPIF protein]
Amlodipine inhibits the reaction [Iohexol results in increased expression of PPIF protein]; CAMK2G protein inhibits the reaction [Iohexol results in increased expression of PPIF protein]; cilnidipine inhibits the reaction [Iohexol results in increased expression of PPIF protein]; Nifedipine inhibits the reaction [Iohexol results in increased expression of PPIF protein] 		CTD PMID:36207783 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,263,541...1,316,954 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO [Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of PYCARD mRNA; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of PYCARD mRNA] CTD PMID:38705399 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression ISO Iohexol results in increased expression of RELA mRNA CTD PMID:29705293 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Iohexol results in decreased expression of RSAD2 mRNA CTD PMID:29705293 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Iohexol results in increased expression of S100A4 mRNA CTD PMID:29705293 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression ISO Iohexol results in increased expression of SOX9 mRNA CTD PMID:29705293 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions EXP
ISO 		Iohexol inhibits the reaction [[Drinking Water deficiency co-treated with Furosemide] results in increased expression of SQSTM1 protein]
[Berberine co-treated with Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of SQSTM1 protein 		CTD PMID:29860548 PMID:38705399 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA]]; Iohexol promotes the reaction [Glycerol results in increased expression of TGFB1 mRNA] CTD PMID:26562095 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression ISO Iohexol results in decreased expression of THY1 protein CTD PMID:29705293 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression 		EXP
ISO 		Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]]; Carnitine inhibits the reaction [Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]]; Iohexol promotes the reaction [Glycerol results in increased expression of TNF mRNA]; Iohexol promotes the reaction [Glycerol results in increased expression of TNF protein]
[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of TNF mRNA; Berberine inhibits the reaction [[Water deficiency co-treated with NG-Nitroarginine Methyl Ester co-treated with Indomethacin co-treated with Iohexol] results in increased expression of TNF mRNA]
Iohexol results in increased expression of TNF protein 		CTD PMID:26562095 PMID:34774977 PMID:38705399 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Iohexol results in increased expression of TP53 mRNA CTD PMID:29705293 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO Iohexol results in increased expression of TUBB3 mRNA CTD PMID:29705293 NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression ISO Iohexol results in decreased expression of USP18 mRNA CTD PMID:29705293 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:156,143,815...156,171,292 		JBrowse link
iomeprol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528 		JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] CTD PMID:26474837 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:36,078,436...36,081,842 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO iomeprol results in increased phosphorylation of MAPK8 protein CTD PMID:21036957 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO iomeprol results in increased phosphorylation of MAPK9 protein CTD PMID:21036957 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase affects expression ISO iomeprol affects the expression of PIM1 protein CTD PMID:21036957 NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,556,113...7,561,764 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation ISO iomeprol results in increased phosphorylation of RELA protein CTD PMID:21036957 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 affects expression ISO iomeprol affects the expression of STAT3 protein modified form CTD PMID:21036957 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
iopamidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Iopamidol results in increased expression of BAK1 mRNA CTD PMID:29705293 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,102,335...5,110,974 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Iopamidol results in increased expression of BAX mRNA CTD PMID:29705293 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Iopamidol results in increased expression of BBC3 mRNA CTD PMID:29705293 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:86,141,603...86,150,666 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression 		ISO Iopamidol results in increased expression of and results in increased cleavage of CASP9 protein
Iopamidol results in increased expression of CASP9 mRNA 		CTD PMID:29705293 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cryab crystallin, alpha B increases expression ISO Iopamidol results in increased expression of CRYAB mRNA CTD PMID:29705293 NCBI chr 8:59,989,885...59,995,532
Ensembl chr 8:59,989,814...59,995,528 		JBrowse link
G Eng endoglin decreases expression ISO Iopamidol results in decreased expression of ENG protein CTD PMID:29705293 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:36,326,202...36,370,933 		JBrowse link
G Fabp3 fatty acid binding protein 3 increases expression ISO Iopamidol results in increased expression of FABP3 mRNA CTD PMID:29705293 NCBI chr 5:147,936,027...147,942,870
Ensembl chr 5:147,936,119...147,942,881 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Iopamidol results in increased expression of FABP4 mRNA CTD PMID:29705293 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Iopamidol results in decreased expression of IFI44 mRNA CTD PMID:29705293 NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Iopamidol results in decreased expression of IFIH1 mRNA CTD PMID:29705293 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression ISO Iopamidol results in increased expression of MAP3K1 mRNA CTD PMID:29705293 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:45,081,889...45,149,897 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases expression ISO Iopamidol results in increased expression of MAPK14 mRNA CTD PMID:29705293 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294 		JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO Iopamidol results in decreased expression of MX1 mRNA CTD PMID:29705293 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 decreases expression ISO Iopamidol results in decreased expression of OAS3 mRNA CTD PMID:29705293 NCBI chr12:41,439,645...41,463,392
Ensembl chr12:41,439,643...41,464,420 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Iopamidol results in increased expression of PMAIP1 mRNA CTD PMID:29705293 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:62,255,598...62,262,382 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression ISO Iopamidol results in increased expression of RELA mRNA CTD PMID:29705293 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Iopamidol results in decreased expression of RSAD2 mRNA CTD PMID:29705293 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Iopamidol results in increased expression of S100A4 mRNA CTD PMID:29705293 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:178,388,526...178,390,837 		JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression ISO Iopamidol results in increased expression of SOX9 mRNA CTD PMID:29705293 NCBI chr10:98,305,744...98,311,250
Ensembl chr10:98,305,744...98,311,250 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Iopamidol results in decreased expression of STAT1 mRNA CTD PMID:29705293 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Thy1 Thy-1 cell surface antigen decreases expression ISO Iopamidol results in decreased expression of THY1 protein CTD PMID:29705293 NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:53,286,148...53,291,540 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Iopamidol results in increased expression of TP53 mRNA CTD PMID:29705293 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression ISO Iopamidol results in increased expression of TUBB3 mRNA CTD PMID:29705293 NCBI chr19:68,365,687...68,374,741
Ensembl chr19:68,365,587...68,374,740 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 decreases expression ISO Iopamidol results in decreased expression of USP18 mRNA CTD PMID:29705293 NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:156,143,815...156,171,292 		JBrowse link
iopromide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 increases expression EXP iopromide results in increased expression of EDN1 protein CTD PMID:21354280 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687 		JBrowse link
G Hexb hexosaminidase subunit beta increases secretion ISO iopromide results in increased secretion of HEXB protein CTD PMID:34774977 NCBI chr 2:30,218,608...30,238,771
Ensembl chr 2:30,218,608...30,238,771 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO iopromide results in decreased phosphorylation of MAPK1 protein CTD PMID:34774977 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO iopromide results in decreased phosphorylation of MAPK3 protein CTD PMID:34774977 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO iopromide affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:69,850,420...69,868,302
Ensembl chr13:69,850,420...69,868,502 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression EXP iopromide results in decreased expression of NOS2 protein CTD PMID:21354280 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880 		JBrowse link
G RT1-Da RT1 class II, locus Da affects expression ISO iopromide affects the expression of HLA-DRA mRNA CTD PMID:25811541 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
ioxaglic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin multiple interactions ISO Ioxaglic Acid inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:98,051,960...98,065,246 		JBrowse link
G Serpinc1 serpin family C member 1 multiple interactions ISO Ioxaglic Acid inhibits the reaction [F2 protein binds to SERPINC1 protein] CTD PMID:2020943 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:75,790,546...75,817,643 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          nitrogen atom 19595
            nitrogen molecular entity 19595
              organonitrogen compound 19403
                carboxamide 17921
                  dicarboxylic acid amide 3162
                    dicarboxylic acid diamide 2702
                      benzenedicarboxamide 64
                        DM-4103 0
                        DM-4107 0
                        N-[4-(1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-ylcarbonyl)benzoyl]-beta-alanine 0
                        iobitridol 0
                        iohexol 46
                        iomeprol 7
                        iopamidol 24
                        ioxaglic acid 2
                        isophthalamide + 7
                        phthalamide + 2
                        terephthalamide + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            heteroorganic entity 20219
                              organochalcogen compound 19904
                                organooxygen compound 19806
                                  carbon oxoacid 19155
                                    carboxylic acid 19152
                                      carboacyl group 18085
                                        univalent carboacyl group 18085
                                          carbamoyl group 17921
                                            carboxamide 17921
                                              dicarboxylic acid amide 3162
                                                dicarboxylic acid diamide 2702
                                                  benzenedicarboxamide 64
                                                    DM-4103 0
                                                    DM-4107 0
                                                    N-[4-(1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-ylcarbonyl)benzoyl]-beta-alanine 0
                                                    iobitridol 0
                                                    iohexol 46
                                                    iomeprol 7
                                                    iopamidol 24
                                                    ioxaglic acid 2
                                                    isophthalamide + 7
                                                    phthalamide + 2
                                                    terephthalamide + 0
paths to the root