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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid
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Accession:CHEBI:385425 term browser browse the term
Definition:A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.
Synonyms:exact_synonym: (Z)-N-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine
 related_synonym: 2-[[(benzhydrylamino)-[(4-cyanophenyl)amino]methylidene]amino]ethanoic acid;   CP-Dpm-GA;   Formula=C23H20N4O2;   InChI=1S/C23H20N4O2/c24-15-17-11-13-20(14-12-17)26-23(25-16-21(28)29)27-22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,22H,16H2,(H,28,29)(H2,25,26,27);   InChIKey=KGHMYJFHUHFOGL-UHFFFAOYSA-N;   N-(4-Cyanophenyl)-N'-(diphenylmethyl)guanidineacetic acid;   N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID;   N-(p-Cyanophenyl)-N'-(diphenylmethyl)-N''-(carboxymethyl)guanidine;   NC-174;   SMILES=OC(=O)C\\N=C(\\NC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)C#N
 alt_id: CHEBI:42679
 xref: CAS:138460-25-0;   DrugBank:DB07816
 xref_mesh: MESH:C083643
 xref: PDB:1ETZ;   PDB:2CGR;   PDBeChem:GAS;   PMID:10993728;   PMID:7893280;   PMID:9871559;   Reaxys:25965952


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[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat3 G protein subunit alpha transducin 3 affects response to substance ISO GNAT3 protein affects the susceptibility to NC 174 CTD PMID:16740645 NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        epitope 7031
          [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    main group molecular entity 19817
                      s-block molecular entity 19653
                        hydrogen molecular entity 19634
                          hydrides 19144
                            inorganic hydride 18161
                              pnictogen hydride 18151
                                nitrogen hydride 18064
                                  azane 17872
                                    ammonia 17871
                                      organic amino compound 17871
                                        amino acid 16060
                                          alpha-amino acid 13932
                                            serine family amino acid 5750
                                              glycine 3327
                                                glycine derivative 3317
                                                  [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
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