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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:indole alkaloid fundamental parent
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Accession:CHEBI:38482 term browser browse the term
Synonyms:related_synonym: indole alkaloid fundamental parents


show annotations for term's descendants           Sort by:
harman term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO AHR mutant form inhibits the reaction [harman results in increased activity of CYP1A1 protein]; AHR mutant form inhibits the reaction [harman results in increased expression of CYP1A1 protein] CTD PMID:20732341 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases expression 		ISO harman results in increased cleavage of CASP3 protein
harman results in increased expression of CASP3 mRNA 		CTD PMID:35985368 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Casp7 caspase 7 increases expression ISO harman results in increased expression of CASP7 mRNA CTD PMID:35985368 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512 		JBrowse link
G Casp9 caspase 9 increases expression ISO harman results in increased expression of CASP9 mRNA CTD PMID:35985368 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase decreases activity ISO harman results in decreased activity of CAT protein CTD PMID:35985368 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression 		ISO
EXP 		AHR mutant form inhibits the reaction [harman results in increased activity of CYP1A1 protein]; AHR mutant form inhibits the reaction [harman results in increased expression of CYP1A1 protein]; Dactinomycin inhibits the reaction [harman results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [harman results in increased activity of CYP1A1 protein]
harman results in increased expression of CYP1A1 mRNA; harman results in increased expression of CYP1A1 protein 		CTD PMID:20732341 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO harman results in increased expression of HMOX1 mRNA CTD PMID:35985368 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Maoa monoamine oxidase A decreases activity ISO harman results in decreased activity of MAOA protein CTD PMID:28057462 NCBI chr  X:8,615,239...8,681,372
Ensembl chr  X:8,615,239...8,682,631 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO harman results in increased expression of NFE2L2 protein CTD PMID:35985368 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO harman results in increased expression of NQO1 mRNA CTD PMID:35985368 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO harman results in increased cleavage of PARP1 protein CTD PMID:35985368 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions
decreases activity 		ISO harman inhibits the reaction [SLC22A1 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide]
harman results in decreased activity of SLC22A1 protein 		CTD PMID:30189235 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity
multiple interactions 		ISO harman results in decreased activity of SLC22A2 protein
harman inhibits the reaction [SLC22A2 protein results in increased import of 4-(4-(dimethylamino)styryl)-1-methylpyridinium iodide] 		CTD PMID:30189235 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019 		JBrowse link
G Taar1 trace-amine-associated receptor 1 increases activity
multiple interactions 		ISO harman results in increased activity of TAAR1 protein
[harman results in increased activity of TAAR1 protein] which results in increased abundance of Cyclic AMP 		CTD PMID:19725810 NCBI chr 1:23,336,978...23,337,976
Ensembl chr 1:23,335,165...23,353,981 		JBrowse link
vincaleukoblastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases response to substance
increases expression 		ISO ABCA2 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA2 mRNA 		CTD PMID:16928819 NCBI chr 3:28,642,660...28,662,689
Ensembl chr 3:28,642,758...28,662,681 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 decreases response to substance
increases expression 		ISO ABCA3 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA3 mRNA 		CTD PMID:16928819 NCBI chr10:13,886,948...13,944,286
Ensembl chr10:13,887,083...13,944,285 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases uptake
decreases activity
multiple interactions
increases export 		ISO ABCB11 protein results in decreased uptake of Vinblastine
Vinblastine results in decreased activity of ABCB11 protein
Vinblastine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
ABCB11 protein results in increased export of Vinblastine 		CTD PMID:10617675 PMID:24014644 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
increases secretion
increases activity
increases expression
affects binding
multiple interactions
affects uptake
increases transport 		ISO
EXP 		ABCB1 protein results in decreased susceptibility to Vinblastine
ABCB1A protein results in increased secretion of Vinblastine
Vinblastine results in increased activity of ABCB1 protein mutant form
Vinblastine results in increased expression of ABCB1 protein
Vinblastine binds to ABCB1 protein
[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine; [Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which affects the susceptibility to Vinblastine; [sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine; [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]; Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form] 		CTD PMID:1967174 PMID:8917702 PMID:9148857 PMID:11355955 PMID:11455017 More... NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases secretion EXP ABCB1B protein results in increased secretion of Vinblastine CTD PMID:12235267 NCBI chr 4:26,197,706...26,280,156
Ensembl chr 4:26,106,903...26,279,567 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance 		ISO
EXP 		ABCC1 protein affects the susceptibility to Vinblastine
ABCC1 protein results in decreased susceptibility to Vinblastine 		CTD PMID:9334814 PMID:11455017 PMID:16156793 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
decreases response to substance
multiple interactions 		ISO
EXP 		ABCC2 protein affects the transport of Vinblastine
ABCC2 protein results in decreased susceptibility to Vinblastine
[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; [verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine] 		CTD PMID:9525973 PMID:11455017 PMID:15849751 PMID:25844889 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471 		JBrowse link
G Ablim1 actin-binding LIM protein 1 affects response to substance ISO ABLIM1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:266,088,868...266,377,169
Ensembl chr 1:266,088,870...266,377,098 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects response to substance ISO ACAT2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:50,100,817...50,135,095 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects response to substance ISO ACOT13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,668,404...40,680,876
Ensembl chr17:40,668,316...40,680,876 		JBrowse link
G Acp1 acid phosphatase 1 affects response to substance ISO ACP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:53,233,937...53,249,576
Ensembl chr 6:53,233,948...53,251,959 		JBrowse link
G Add3 adducin 3 affects response to substance ISO ADD3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:262,152,722...262,260,504
Ensembl chr 1:262,154,996...262,260,504 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Vinblastine results in decreased expression of AIF1 mRNA CTD PMID:20624997 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Vinblastine results in decreased expression of AK1 mRNA CTD PMID:20624997 NCBI chr 3:36,310,113...36,320,760
Ensembl chr 3:36,310,197...36,320,757 		JBrowse link
G Aox1 aldehyde oxidase 1 affects response to substance ISO AOX1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980 		JBrowse link
G Apln apelin decreases expression EXP Vinblastine results in decreased expression of APLN mRNA CTD PMID:20624997 NCBI chr  X:132,058,739...132,091,518
Ensembl chr  X:132,081,759...132,091,246 		JBrowse link
G Atp5me ATP synthase membrane subunit e affects response to substance ISO ATP5ME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,464,788...1,465,989
Ensembl chr14:1,464,800...1,465,988 		JBrowse link
G Atp5mf ATP synthase membrane subunit f affects response to substance ISO ATP5MF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:14,535,435...14,542,007
Ensembl chr12:14,522,832...14,542,709 		JBrowse link
G Aurkb aurora kinase B affects response to substance ISO AURKB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:54,243,116...54,249,675
Ensembl chr10:54,242,850...54,252,285 		JBrowse link
G Axl Axl receptor tyrosine kinase affects response to substance ISO AXL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:90,392,864...90,424,123
Ensembl chr 1:90,392,864...90,424,009 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance ISO BIRC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects response to substance ISO BIRC3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:13,285,703...13,298,590 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Vinblastine CTD PMID:17437058 NCBI chr 3:188,425,392...188,430,174
Ensembl chr 3:188,425,392...188,430,174 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase affects response to substance ISO BUB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:135,472,582...135,504,921 		JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 affects response to substance ISO C5ORF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:37,064,889...37,077,493
Ensembl chr10:37,064,728...37,077,493 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions 		EXP
ISO 		Vinblastine results in increased cleavage of CASP3 protein
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] 		CTD PMID:16545138 PMID:20624997 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cat catalase affects response to substance ISO CAT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Vinblastine results in increased expression of CCL2 mRNA CTD PMID:20624997 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875 		JBrowse link
G Ccn2 cellular communication network factor 2 affects response to substance ISO CCN2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:22,621,501...22,624,976 		JBrowse link
G Ccnb1 cyclin B1 affects response to substance
increases response to substance 		ISO CCNB1 protein affects the susceptibility to Vinblastine
CCNB1 protein results in increased susceptibility to Vinblastine 		CTD PMID:16217747 PMID:16849574 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225 		JBrowse link
G Ccnb2 cyclin B2 affects response to substance ISO CCNB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:79,968,465...79,981,682 		JBrowse link
G Cd14 CD14 molecule increases expression EXP Vinblastine results in increased expression of CD14 mRNA CTD PMID:20624997 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292 		JBrowse link
G Cd40lg CD40 ligand decreases response to substance
multiple interactions 		ISO CD40LG protein results in decreased susceptibility to Vinblastine
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]] 		CTD PMID:16545138 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd44 CD44 molecule increases expression EXP Vinblastine results in increased expression of CD44 mRNA CTD PMID:20624997 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424 		JBrowse link
G Cdca8 cell division cycle associated 8 affects response to substance ISO CDCA8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:142,461,082...142,483,336
Ensembl chr 5:142,461,084...142,483,283 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects response to substance ISO CDK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects response to substance ISO CDK2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Vinblastine results in increased expression of CDKN1A mRNA CTD PMID:20624997 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects response to substance ISO CDKN2C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Vinblastine results in decreased expression of CDKN3 mRNA CTD PMID:20624997 NCBI chr15:22,502,299...22,513,725
Ensembl chr15:22,502,382...22,513,722 		JBrowse link
G Cenpa centromere protein A affects response to substance ISO CENPA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:31,420,062...31,431,703 JBrowse link
G Ckap2 cytoskeleton associated protein 2 affects response to substance ISO CKAP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:76,542,114...76,567,297
Ensembl chr16:76,542,104...76,567,352 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects response to substance ISO COX17 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:75,906,245...75,912,036
Ensembl chr11:75,906,248...75,912,019 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects response to substance ISO COX5A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 affects response to substance ISO COX6B1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:95,002,513...95,011,516
Ensembl chr 1:95,001,707...95,011,431
Ensembl chr 5:95,001,707...95,011,431 		JBrowse link
G Cp ceruloplasmin increases expression EXP Vinblastine results in increased expression of CP mRNA CTD PMID:20624997 NCBI chr 2:104,368,336...104,427,119
Ensembl chr 2:104,368,456...104,427,087 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 affects response to substance ISO CREG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:80,552,779...80,565,272
Ensembl chr13:80,549,933...80,565,272 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain affects response to substance ISO CRIPT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:13,334,978...13,342,934
Ensembl chr 6:13,334,954...13,345,044 		JBrowse link
G Ctss cathepsin S increases expression EXP Vinblastine results in increased expression of CTSS mRNA CTD PMID:20624997 NCBI chr 2:185,775,316...185,803,440
Ensembl chr 2:185,775,296...185,803,440 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:11602686 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012 		JBrowse link
G Dcps decapping enzyme, scavenger affects response to substance ISO DCPS protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:41,729,507...41,782,222
Ensembl chr 8:41,724,563...41,782,222 		JBrowse link
G Ddx23 DEAD-box helicase 23 affects response to substance ISO DDX23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:131,676,636...131,693,917
Ensembl chr 7:131,676,636...131,689,074 		JBrowse link
G Dera deoxyribose-phosphate aldolase affects response to substance ISO DERA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:172,394,971...172,473,746
Ensembl chr 4:172,394,962...172,490,142 		JBrowse link
G Dffb DNA fragmentation factor subunit beta affects response to substance ISO DFFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:169,804,873...169,817,157
Ensembl chr 5:169,804,889...169,817,225 		JBrowse link
G Dipk1a divergent protein kinase domain 1A affects response to substance ISO DIPK1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,917,353...1,988,188
Ensembl chr14:1,917,324...1,988,678 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects response to substance ISO DKK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:237,794,969...237,798,650 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:175,672,834...175,715,867
Ensembl chr 1:175,672,834...175,715,186 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON affects response to substance ISO DONSON protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:44,405,794...44,419,099
Ensembl chr11:44,405,804...44,418,791 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 affects response to substance ISO DSCC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:88,372,349...88,390,815
Ensembl chr 7:88,372,146...88,387,973 		JBrowse link
G E2f1 E2F transcription factor 1 increases response to substance ISO E2F1 protein results in increased susceptibility to Vinblastine CTD PMID:16849574 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:163,524,739...163,535,563 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Vinblastine results in increased expression of EDNRB mRNA CTD PMID:20624997 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:87,057,691...87,086,765 		JBrowse link
G Efcab7 EF-hand calcium binding domain 7 affects response to substance ISO EFCAB7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:119,640,841...119,691,566
Ensembl chr 5:119,640,761...119,691,563 		JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:5,866,869...5,901,533
Ensembl chr10:5,866,922...5,901,532 		JBrowse link
G Epcam epithelial cell adhesion molecule affects response to substance ISO EPCAM protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:12,633,715...12,649,678
Ensembl chr 6:12,631,611...12,649,702 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP Vinblastine results in increased expression of EPRS1 mRNA CTD PMID:20624997 NCBI chr13:99,431,955...99,503,510
Ensembl chr13:99,433,130...99,503,509 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects response to substance ISO ERBB2 protein affects the susceptibility to Vinblastine CTD PMID:10327070 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,907,460...83,931,481 		JBrowse link
G Ereg epiregulin affects response to substance ISO EREG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,311,485...17,325,260 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression EXP Vinblastine results in decreased expression of ESM1 mRNA CTD PMID:20624997 NCBI chr 2:46,609,253...46,617,991
Ensembl chr 2:46,609,204...46,617,990 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects response to substance ISO ETFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:102,988,499...103,002,663
Ensembl chr 1:102,988,499...103,002,659 		JBrowse link
G Exosc9 exosome component 9 affects response to substance ISO EXOSC9 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:121,344,154...121,355,110
Ensembl chr 2:121,344,175...121,374,232 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Vinblastine results in increased expression of F3 mRNA CTD PMID:20624997 NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:212,511,680...212,523,369 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C affects response to substance ISO FAM3C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:51,805,686...51,853,030
Ensembl chr 4:51,805,703...51,853,030 		JBrowse link
G Fancl FA complementation group L affects response to substance ISO FANCL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:104,449,403...104,515,297
Ensembl chr14:104,394,590...104,515,297 		JBrowse link
G Faslg Fas ligand increases expression ISO Vinblastine results in increased expression of FASLG protein CTD PMID:11716366 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:76,688,243...76,695,503 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Vinblastine results in increased expression of FCGR2B mRNA CTD PMID:20624997 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:85,725,897...85,740,517 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 affects response to substance ISO FEN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:216,269,163...216,275,016 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A affects response to substance ISO FKBP1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:160,500,748...160,520,492
Ensembl chr 3:160,500,726...160,524,233 		JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor affects response to substance ISO FLI1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:39,089,526...39,209,511
Ensembl chr 8:39,089,533...39,208,557 		JBrowse link
G Fn1 fibronectin 1 affects response to substance ISO FN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects response to substance ISO FOSL1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:212,183,833...212,192,391 		JBrowse link
G G0s2 G0/G1switch 2 affects response to substance ISO G0S2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Vinblastine results in increased expression of GADD45A mRNA CTD PMID:20624997 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:97,484,502...97,486,807 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Vinblastine results in increased expression of GADD45B mRNA CTD PMID:20624997 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:9,428,689...9,430,718 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Vinblastine results in increased expression of GADD45G mRNA CTD PMID:20624997 NCBI chr17:13,528,606...13,530,351
Ensembl chr17:13,528,610...13,530,369 		JBrowse link
G Gas7 growth arrest specific 7 decreases expression EXP Vinblastine results in decreased expression of GAS7 mRNA CTD PMID:20624997 NCBI chr10:52,651,690...52,882,244
Ensembl chr10:52,651,690...52,882,244 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase affects response to substance ISO GGCT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:85,453,387...85,459,597
Ensembl chr 4:85,453,387...85,470,224 		JBrowse link
G Ggcx gamma-glutamyl carboxylase affects response to substance ISO GGCX protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:106,027,918...106,043,653
Ensembl chr 4:106,027,912...106,043,923 		JBrowse link
G Gmnn geminin, DNA replication inhibitor affects response to substance ISO GMNN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,729,760...40,738,077
Ensembl chr17:40,729,824...40,738,068 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta affects response to substance ISO GNPTAB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:24,687,923...24,754,821
Ensembl chr 7:24,687,969...24,754,821 		JBrowse link
G Gpr176 G protein-coupled receptor 176 affects response to substance ISO GPR176 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:125,690,750...125,791,172
Ensembl chr 3:125,690,751...125,791,172 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects response to substance ISO GPSM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:199,015,250...199,063,788
Ensembl chr 2:199,015,250...199,063,056 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance EXP GSTP1 protein results in decreased susceptibility to Vinblastine CTD PMID:11455017 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705 		JBrowse link
G Gtf2i general transcription factor II I affects response to substance ISO GTF2I protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:28,037,344...28,112,677
Ensembl chr12:28,037,853...28,112,677 		JBrowse link
G Gtf3a general transcription factor III A affects response to substance ISO GTF3A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:13,250,643...13,258,587
Ensembl chr12:13,250,644...13,258,587 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 affects response to substance ISO GTSE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:118,829,793...118,846,662
Ensembl chr 7:118,829,903...118,846,661 		JBrowse link
G Gusb glucuronidase, beta affects response to substance ISO GUSB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024 		JBrowse link
G H1f2 H1.2 linker histone, cluster member affects response to substance ISO H1-2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:41,818,962...41,820,453
Ensembl chr17:41,779,051...41,822,317 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase affects response to substance ISO HADH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 affects response to substance ISO HCLS1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:77,322,873...77,346,333
Ensembl chr11:77,322,873...77,346,387 		JBrowse link
G Hmgb1 high mobility group box 1 affects response to substance ISO HMGB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327 		JBrowse link
G Hmgb2 high mobility group box 2 affects response to substance ISO HMGB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:37,721,379...37,723,860 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 affects response to substance ISO HMGN3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:92,902,555...92,939,980 JBrowse link
G Hmmr hyaluronan-mediated motility receptor affects response to substance ISO HMMR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:25,635,249...25,665,389
Ensembl chr10:25,635,915...25,665,390 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Vinblastine results in increased expression of HMOX1 mRNA CTD PMID:20624997 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818 		JBrowse link
G Homer1 homer scaffold protein 1 affects response to substance ISO HOMER1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:26,279,012...26,388,279
Ensembl chr 2:26,278,105...26,381,657 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
decreases expression 		EXP
ISO 		Vinblastine results in increased expression of ICAM1 mRNA
Vinblastine results in decreased expression of ICAM1 mRNA; Vinblastine results in decreased expression of ICAM1 protein 		CTD PMID:12649748 PMID:20624997 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617 		JBrowse link
G Id2 inhibitor of DNA binding 2 affects response to substance ISO ID2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects response to substance ISO IDH2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:79,391,367...79,525,923
Ensembl chr 4:79,393,067...79,525,730 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation
multiple interactions 		ISO Vinblastine results in increased phosphorylation of IKBKB protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein] 		CTD PMID:17029595 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 affects response to substance ISO IL13RA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:115,814,620...115,886,080
Ensembl chr  X:115,814,622...115,841,455 		JBrowse link
G Il1b interleukin 1 beta affects response to substance
increases expression 		ISO
EXP 		IL1B protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of IL1B mRNA 		CTD PMID:16217747 PMID:20624997 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601 		JBrowse link
G Il6 interleukin 6 decreases chemical synthesis
increases stability 		ISO Vinblastine results in decreased chemical synthesis of IL6 protein
Vinblastine results in increased stability of IL6 mRNA 		CTD PMID:16499908 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Vinblastine results in decreased expression of INHA mRNA CTD PMID:20624997 NCBI chr 9:84,443,109...84,446,010
Ensembl chr 9:84,443,109...84,446,009 		JBrowse link
G Inhba inhibin subunit beta A affects response to substance ISO INHBA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:53,791,444...53,804,508 		JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO Vinblastine results in decreased expression of ITGAL mRNA; Vinblastine results in decreased expression of ITGAL protein CTD PMID:12649748 NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:191,348,542...191,386,225 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 affects response to substance ISO ITGB1BP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:46,549,994...46,564,735
Ensembl chr 6:46,549,999...46,564,398 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation 		ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein] CTD PMID:12221076 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 affects response to substance ISO KANK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:232,381,720...232,500,834
Ensembl chr 1:232,445,658...232,500,839 		JBrowse link
G Kazn kazrin, periplakin interacting protein affects response to substance ISO KAZN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:159,675,803...160,666,084
Ensembl chr 5:159,675,803...160,664,154 		JBrowse link
G Kif11 kinesin family member 11 affects response to substance ISO KIF11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:244,494,916...244,589,250
Ensembl chr 1:244,494,875...244,589,250 		JBrowse link
G Kif15 kinesin family member 15 affects response to substance ISO KIF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:131,479,340...131,550,209
Ensembl chr 8:131,479,337...131,550,202 		JBrowse link
G Kif1b kinesin family member 1B affects response to substance ISO KIF1B protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:164,894,763...165,008,841 		JBrowse link
G Kif20a kinesin family member 20A affects response to substance ISO KIF20A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,504,072...26,512,909 		JBrowse link
G Kif23 kinesin family member 23 affects response to substance ISO KIF23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:71,293,482...71,320,856 		JBrowse link
G Kif4a kinesin family member 4A affects response to substance ISO KIF4A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:69,761,803...69,864,335
Ensembl chr  X:69,761,883...69,864,335 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 affects response to substance ISO KPNA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:92,433,678...92,445,841
Ensembl chr10:92,433,679...92,445,937 		JBrowse link
G Lmnb1 lamin B1 affects response to substance ISO LMNB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:52,373,939...52,413,284
Ensembl chr18:52,373,757...52,413,283 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 affects response to substance ISO LPAR1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:78,024,139...78,147,071
Ensembl chr 5:78,024,139...78,142,188 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 affects response to substance ISO LRRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:87,120,281...87,289,748
Ensembl chr 8:87,119,975...87,286,853 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated affects response to substance ISO LSM7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:9,507,373...9,509,787
Ensembl chr 7:9,507,367...9,514,115 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 affects response to substance ISO LTBP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:110,161,029...110,261,586
Ensembl chr 6:110,161,029...110,257,298 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 affects response to substance ISO MAD2L1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:97,236,503...97,243,222 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions 		ISO Vinblastine results in increased phosphorylation of MAPK8 protein
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein] 		CTD PMID:12221076 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation 		ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 affects response to substance ISO MAPKAPK5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:40,654,220...40,673,740
Ensembl chr12:40,654,423...40,677,170 		JBrowse link
G Melk maternal embryonic leucine zipper kinase affects response to substance ISO MELK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:63,336,106...63,396,247 		JBrowse link
G Mme membrane metallo-endopeptidase affects response to substance ISO MME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:149,872,291...149,953,463 		JBrowse link
G Mmp1 matrix metallopeptidase 1 affects response to substance ISO MMP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964 		JBrowse link
G Mok MOK protein kinase affects response to substance ISO MOK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:135,645,018...135,675,894
Ensembl chr 6:135,645,018...135,676,174 		JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 affects response to substance ISO MRPL57 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:36,086,457...36,087,319
Ensembl chr15:36,086,457...36,087,298 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects response to substance
increases expression 		ISO
EXP 		MYC protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of MYC mRNA 		CTD PMID:18802399 PMID:20624997 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028 		JBrowse link
G Mycbp Myc binding protein affects response to substance ISO MYCBP protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:141,420,727...141,427,938
Ensembl chr 5:141,420,707...141,430,681 		JBrowse link
G Nbn nibrin increases expression EXP Vinblastine results in increased expression of NBN mRNA CTD PMID:20624997 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:34,256,627...34,291,162 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G affects response to substance ISO NCAPG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:69,616,473...69,645,445
Ensembl chr14:69,616,473...69,645,445 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects response to substance ISO NCAPH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:134,825,271...134,852,502
Ensembl chr 3:134,825,271...134,852,502 		JBrowse link
G Ndc80 NDC80 kinetochore complex component affects response to substance ISO NDC80 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:118,853,806...118,887,582
Ensembl chr 9:118,853,806...118,887,568 		JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 affects response to substance ISO NDUFA1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:121,289,904...121,293,555
Ensembl chr  X:121,289,925...121,293,555 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 affects response to substance ISO NDUFA13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:19,560,526...19,567,500
Ensembl chr 7:32,257,006...32,257,492 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 affects response to substance ISO NDUFA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:74,512,928...74,515,558
Ensembl chr 1:74,512,928...74,515,558 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 affects response to substance ISO NDUFA7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:15,311,446...15,324,226
Ensembl chr 7:15,311,286...15,334,138 		JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 affects response to substance ISO NDUFB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:69,334,307...69,341,394
Ensembl chr 4:69,334,307...69,340,136
Ensembl chr15:69,334,307...69,340,136 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 affects response to substance ISO NDUFC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:137,597,944...137,601,819
Ensembl chr 2:137,600,156...137,601,735 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 affects response to substance ISO NDUFC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:161,122,370...161,129,413
Ensembl chr 1:161,123,150...161,129,419 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 affects response to substance ISO NDUFS6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:31,797,400...31,805,965
Ensembl chr 1:31,797,394...31,805,965 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 affects response to substance ISO NDUFV2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:113,137,305...113,157,571
Ensembl chr 9:113,137,306...113,157,520 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 decreases localization ISO Vinblastine results in decreased localization of NFATC4 protein CTD PMID:17044076 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:33,274,153...33,285,582 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions 		ISO Vinblastine results in increased phosphorylation of NFKBIA protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein] 		CTD PMID:17029595 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072 		JBrowse link
G Ngf nerve growth factor decreases response to substance EXP Vinblastine results in decreased susceptibility to NGF protein CTD PMID:9524088 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834 		JBrowse link
G Npy neuropeptide Y decreases expression EXP Vinblastine results in decreased expression of NPY mRNA CTD PMID:1671012 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:80,212,111...80,219,310 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Vinblastine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity 		ISO [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein] CTD PMID:20041327 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380 		JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor affects response to substance ISO NSMAF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:24,315,319...24,378,346
Ensembl chr 5:24,315,319...24,375,355 		JBrowse link
G Nudt15 nudix hydrolase 15 affects response to substance ISO NUDT15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:55,117,312...55,123,983 JBrowse link
G Nudt4 nudix hydrolase 4 affects response to substance ISO NUDT4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:32,074,978...32,091,491
Ensembl chr 7:32,075,002...32,091,491 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 affects response to substance ISO NUSAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:127,057,265...127,087,237 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 affects response to substance ISO OAZ1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:9,534,530...9,536,990
Ensembl chr 7:9,533,811...9,536,990 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:9270009 NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:46,058,463...46,065,146 		JBrowse link
G Oip5 Opa interacting protein 5 affects response to substance ISO OIP5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:127,047,559...127,057,043
Ensembl chr 3:127,047,559...127,057,043 		JBrowse link
G Or1i2 olfactory receptor family 1 subfamily I member 2 affects response to substance ISO OR1I1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:11,636,515...11,637,456
Ensembl chr 7:11,636,515...11,637,456 		JBrowse link
G Orc6 origin recognition complex, subunit 6 affects response to substance ISO ORC6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr19:37,931,085...37,938,856
Ensembl chr19:37,931,090...37,938,856 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 affects response to substance ISO OSBPL10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:123,536,818...123,796,822
Ensembl chr 8:123,539,235...123,796,822 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] CTD PMID:16545138 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta affects response to substance ISO PDHB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:19,182,789...19,188,731
Ensembl chr15:19,181,208...19,188,976 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor affects response to substance ISO PELO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:48,530,902...48,532,670
Ensembl chr 2:48,530,907...48,532,761 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects response to substance ISO PGRMC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:120,698,610...120,706,805
Ensembl chr  X:120,698,610...120,706,805 		JBrowse link
G Pir pirin affects response to substance ISO PIR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:33,740,428...33,851,049
Ensembl chr  X:33,740,429...33,851,049 		JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression EXP Vinblastine results in increased expression of PLAGL1 mRNA CTD PMID:20624997 NCBI chr 1:9,297,066...9,337,394
Ensembl chr 1:9,330,204...9,337,394 		JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP Vinblastine results in increased expression of PLAT mRNA CTD PMID:20624997 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:75,943,064...75,967,696 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,505,487...3,512,030 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Vinblastine results in increased expression of PLAUR mRNA CTD PMID:20624997 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Vinblastine results in increased expression of PPP1R15A mRNA CTD PMID:20624997 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 affects response to substance ISO PRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:143,659,312...143,681,019
Ensembl chr 1:143,659,481...143,681,012 		JBrowse link
G Prkcd protein kinase C, delta affects localization ISO Vinblastine affects the localization of PRKCD protein CTD PMID:9852137 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects response to substance ISO PSMB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:65,115,770...65,136,516
Ensembl chr 1:65,114,724...65,136,640 		JBrowse link
G Psme4 proteasome activator subunit 4 affects response to substance ISO PSME4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:108,706,643...108,810,330
Ensembl chr14:108,706,643...108,810,328 		JBrowse link
G Ptges3 prostaglandin E synthase 3 affects response to substance ISO PTGES3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:1,075,230...1,092,363
Ensembl chr 7:1,075,227...1,092,695 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin affects response to substance ISO PTTG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:28,394,940...28,406,410
Ensembl chr10:28,394,814...28,406,309 		JBrowse link
G Ptx3 pentraxin 3 affects response to substance ISO PTX3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:152,781,955...152,803,372 		JBrowse link
G Qrich1 glutamine-rich 1 increases phosphorylation ISO Vinblastine results in increased phosphorylation of QRICH1 protein CTD PMID:17510977 NCBI chr 8:118,095,435...118,135,001
Ensembl chr 8:118,095,429...118,134,999 		JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 affects response to substance ISO RAB11FIP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:71,589,753...71,620,341
Ensembl chr16:71,589,753...71,620,341 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 affects response to substance ISO RACGAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:132,629,789...132,659,738
Ensembl chr 7:132,620,595...132,659,738 		JBrowse link
G Ranbp1 RAN binding protein 1 affects response to substance ISO RANBP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:96,246,912...96,255,145
Ensembl chr11:96,246,740...96,255,145 		JBrowse link
G Rassf1 Ras association domain family member 1 increases expression EXP Vinblastine results in increased expression of RASSF1 mRNA CTD PMID:20624997 NCBI chr 8:117,103,665...117,114,805
Ensembl chr 8:117,103,362...117,114,805 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit affects response to substance ISO REV3L protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:44,686,482...44,844,668
Ensembl chr20:44,686,940...44,844,668 		JBrowse link
G Rfc5 replication factor C subunit 5 affects response to substance ISO RFC5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:44,868,322...44,877,879
Ensembl chr12:44,862,329...44,878,151 		JBrowse link
G Rpa3 replication protein A3 affects response to substance ISO RPA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:37,270,966...37,273,997
Ensembl chr 4:37,270,966...37,274,183 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects response to substance ISO RRM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:47,044,755...47,075,370
Ensembl chr 6:47,067,690...47,075,370 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Vinblastine results in increased expression of S100A8 mRNA CTD PMID:20624997 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP Vinblastine results in increased expression of S100A9 mRNA CTD PMID:20624997 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:178,487,941...178,490,870 		JBrowse link
G Sele selectin E increases expression EXP Vinblastine results in increased expression of SELE mRNA CTD PMID:20624997 NCBI chr13:78,935,997...78,945,905
Ensembl chr13:78,936,036...78,945,903 		JBrowse link
G Serpinb2 serpin family B member 2 affects response to substance ISO SERPINB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:24,051,933...24,065,032
Ensembl chr13:24,056,021...24,065,031 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
affects response to substance 		EXP
ISO 		Vinblastine results in increased expression of SERPINE1 mRNA
SERPINE1 protein affects the susceptibility to Vinblastine 		CTD PMID:16217747 PMID:20624997 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:25,237,952...25,248,357 		JBrowse link
G Sfxn1 sideroflexin 1 affects response to substance ISO SFXN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456 		JBrowse link
G Shtn1 shootin 1 affects response to substance ISO SHTN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:268,108,095...268,211,947
Ensembl chr 1:268,108,097...268,211,947 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex affects response to substance ISO SKIC8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:63,999,669...64,016,959
Ensembl chr 8:63,999,671...64,016,846 		JBrowse link
G Skp2 S-phase kinase associated protein 2 affects response to substance ISO SKP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:59,888,413...59,916,438 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects response to substance ISO SLC22A3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353 		JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 affects response to substance ISO SNRNP25 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:15,924,932...15,928,279
Ensembl chr10:15,924,940...15,928,252 		JBrowse link
G Snx10 sorting nexin 10 affects response to substance ISO SNX10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:81,943,262...82,007,667
Ensembl chr 4:81,943,287...82,007,651 		JBrowse link
G Sod1 superoxide dismutase 1 affects response to substance ISO SOD1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression 		ISO bisindolylmaleimide I inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA] CTD PMID:9852137 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168 		JBrowse link
G Sort1 sortilin 1 affects response to substance ISO SORT1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:198,612,148...198,690,481 		JBrowse link
G Spon1 spondin 1 increases expression EXP Vinblastine results in increased expression of SPON1 mRNA CTD PMID:20624997 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:177,363,197...177,662,676 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects response to substance ISO SRD5A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:35,514,846...35,548,903 		JBrowse link
G Srgn serglycin affects response to substance ISO SRGN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:30,985,508...31,022,296
Ensembl chr20:30,985,508...31,000,327 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT1 protein CTD PMID:28086195 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359 		JBrowse link
G Stc2 stanniocalcin 2 affects response to substance ISO STC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447 		JBrowse link
G Stk26 serine/threonine kinase 26 affects response to substance ISO STK26 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:135,195,176...135,259,994
Ensembl chr  X:135,195,204...135,259,993 		JBrowse link
G Strn striatin affects response to substance ISO STRN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:22,087,419...22,174,284
Ensembl chr 6:22,087,497...22,193,048 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta affects response to substance ISO SUCLA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:55,161,894...55,215,031
Ensembl chr15:55,161,868...55,215,029 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects response to substance ISO SUCLG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:106,866,329...106,895,686
Ensembl chr 4:106,866,114...106,895,689 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects response to substance ISO SULT1A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 affects response to substance ISO SYDE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:11,683,505...11,689,491
Ensembl chr 7:11,681,111...11,690,443 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 affects response to substance ISO TBC1D4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:84,670,756...84,848,876
Ensembl chr15:84,670,756...84,848,693 		JBrowse link
G Tdg thymine-DNA glycosylase affects response to substance ISO TDG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:22,965,388...22,990,311
Ensembl chr 7:22,965,388...22,985,100 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance
increases expression 		ISO
EXP 		TFPI2 protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of TFPI2 mRNA 		CTD PMID:16217747 PMID:20624997 NCBI chr 4:32,936,462...32,941,385
Ensembl chr 4:32,936,854...32,941,426 		JBrowse link
G Thbd thrombomodulin increases expression EXP Vinblastine results in increased expression of THBD mRNA CTD PMID:20624997 NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:156,306,632...156,320,582 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Vinblastine results in increased expression of THBS1 mRNA CTD PMID:20624997 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Vinblastine results in increased expression of TIMP1 mRNA CTD PMID:20624997 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135 		JBrowse link
G Tmem134 transmembrane protein 134 affects response to substance ISO TMEM134 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:210,848,761...210,857,735
Ensembl chr 1:210,848,578...210,858,861 		JBrowse link
G Tmem14a transmembrane protein 14A affects response to substance ISO TMEM14A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:31,136,963...31,148,800 		JBrowse link
G Tmem156 transmembrane protein 156 affects response to substance ISO TMEM156 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:43,568,131...43,606,109
Ensembl chr14:43,577,023...43,606,109 		JBrowse link
G Tmem97 transmembrane protein 97 affects response to substance ISO TMEM97 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:63,936,276...63,945,359
Ensembl chr10:63,936,271...63,945,818 		JBrowse link
G Tmpo thymopoietin affects response to substance ISO TMPO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:27,529,977...27,554,980
Ensembl chr 7:27,529,978...27,554,937 		JBrowse link
G Top2a DNA topoisomerase II alpha affects response to substance ISO TOP2A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression
affects response to substance 		EXP
ISO 		Vinblastine results in increased expression of TPD52L1 mRNA
TPD52L1 protein affects the susceptibility to Vinblastine 		CTD PMID:16217747 PMID:20624997 NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:27,991,131...28,110,158 		JBrowse link
G Trim2 tripartite motif-containing 2 affects response to substance ISO TRIM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:171,798,654...171,950,193
Ensembl chr 2:171,798,660...171,913,468 		JBrowse link
G Trmt5 tRNA methyltransferase 5 affects response to substance ISO TRMT5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:97,702,375...97,723,534
Ensembl chr 6:97,705,479...97,723,399 		JBrowse link
G Tspan13 tetraspanin 13 affects response to substance ISO TSPAN13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:58,466,051...58,492,804
Ensembl chr 6:58,465,684...58,492,819 		JBrowse link
G Ttf2 transcription termination factor 2 affects response to substance ISO TTF2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:191,054,942...191,086,331
Ensembl chr 2:191,054,966...191,086,386 		JBrowse link
G Ttk Ttk protein kinase affects response to substance ISO TTK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:93,632,678...93,672,664
Ensembl chr 8:93,634,319...93,672,664 		JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression EXP Vinblastine results in decreased expression of TUBA1B mRNA CTD PMID:20624997 NCBI chr 7:131,969,606...131,972,587
Ensembl chr 7:131,968,770...131,996,035 		JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP Vinblastine results in decreased expression of TUBA4A mRNA CTD PMID:20624997 NCBI chr 9:84,158,871...84,174,041
Ensembl chr 9:84,158,280...84,162,584 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Vinblastine results in decreased expression of TUBB4B mRNA CTD PMID:20624997 NCBI chr 3:28,435,999...28,438,455
Ensembl chr 3:28,435,148...28,439,719 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Vinblastine results in decreased expression of TUBB5 mRNA CTD PMID:20624997 NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726 		JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression EXP Vinblastine results in decreased expression of TUBG1 mRNA CTD PMID:20624997 NCBI chr10:86,553,143...86,559,733
Ensembl chr10:86,552,499...86,559,730 		JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X affects response to substance ISO UQCR10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:83,789,657...83,791,914
Ensembl chr14:83,789,658...83,791,914 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Vinblastine results in increased expression of VCAM1 mRNA CTD PMID:20624997 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Vinblastine results in decreased expression of VEGFA mRNA CTD PMID:20624997 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194 		JBrowse link
G Vegfc vascular endothelial growth factor C affects response to substance ISO VEGFC protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887 		JBrowse link
G Vwf von Willebrand factor increases expression EXP Vinblastine results in increased expression of VWF mRNA CTD PMID:20624997 NCBI chr 4:160,042,900...160,177,757
Ensembl chr 4:160,047,982...160,177,757 		JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 affects response to substance ISO WSB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:44,878,483...44,899,474
Ensembl chr12:44,878,509...44,899,474 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects response to substance ISO YWHAQ protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:46,664,358...46,694,875
Ensembl chr 6:46,664,358...46,694,875 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 affects response to substance ISO ZDHHC11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:31,124,900...31,156,075
Ensembl chr 1:31,124,900...31,155,498 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 affects response to substance ISO ZFP36L2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653 		JBrowse link
G Zwint ZW10 interacting kinetochore protein affects response to substance ISO ZWINT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,937,396...15,953,203 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    chemical entity 20872
      atom 20872
        nonmetal atom 20781
          carbon atom 20706
            organic molecular entity 20706
              organic fundamental parent 16947
                natural product fundamental parent 331
                  alkaloid fundamental parent 296
                    indole alkaloid fundamental parent 268
                      18-oxayohimban 0
                      ajmalan 0
                      akuammilan 0
                      alstophyllan 0
                      aspidofractinine 0
                      aspidospermidine 0
                      corynan 0
                      corynoxan 0
                      curan 0
                      eburnamenine 0
                      ergoline 0
                      ergotaman 0
                      formosanan 0
                      harman 14
                      ibogamine 0
                      kopsan 0
                      lycorenan 0
                      sarpagan 0
                      strychnidine 0
                      tazettine 0
                      tubulosan 0
                      vincaleukoblastine 259
                      vincane 0
                      vobasan 0
                      vobtusine 0
                      yohimban 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20874
    subatomic particle 20883
      composite particle 20883
        hadron 20872
          baryon 20883
            nucleon 20872
              atomic nucleus 20883
                atom 20872
                  main group element atom 20796
                    main group molecular entity 20809
                      s-block molecular entity 20147
                        hydrogen molecular entity 20117
                          hydrides 17673
                            organic hydride 16947
                              organic fundamental parent 16947
                                natural product fundamental parent 331
                                  alkaloid fundamental parent 296
                                    indole alkaloid fundamental parent 268
                                      18-oxayohimban 0
                                      ajmalan 0
                                      akuammilan 0
                                      alstophyllan 0
                                      aspidofractinine 0
                                      aspidospermidine 0
                                      corynan 0
                                      corynoxan 0
                                      curan 0
                                      eburnamenine 0
                                      ergoline 0
                                      ergotaman 0
                                      formosanan 0
                                      harman 14
                                      ibogamine 0
                                      kopsan 0
                                      lycorenan 0
                                      sarpagan 0
                                      strychnidine 0
                                      tazettine 0
                                      tubulosan 0
                                      vincaleukoblastine 259
                                      vincane 0
                                      vobasan 0
                                      vobtusine 0
                                      yohimban 0
paths to the root