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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:formamidine
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Accession:CHEBI:38477 term browser browse the term
Definition:The smallest member of the class of carboxamidines being formic acid with the O and OH groups from the carboxy function replaced by NH and NH2 groups respectively. The parent of the class of formamidines.
Synonyms:exact_synonym: methanimidamide
 related_synonym: Formula=CH4N2;   HC(=NH)-NH2;   InChI=1S/CH4N2/c2-1-3/h1H,(H3,2,3);   InChIKey=PNKUSGQVOMIXLU-UHFFFAOYSA-N;   SMILES=[H]C(N)=N;   formimidamide;   imidoformamide;   methanoic acid amidine
 xref: CAS:463-52-5;   Gmelin:217264;   PMID:11377388;   Reaxys:878149


show annotations for term's descendants           Sort by:
formetanate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP formetanate results in decreased activity of ACHE protein CTD PMID:19934164 PMID:21251949 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP [Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein CTD PMID:22649187 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO formetanate results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO formetanate results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO formetanate results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO formetanate results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO formetanate results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      application 19695
        solvent 17235
          formic acid 9094
            formamidine 7
              (aminomethylidene)amino group 0
              N'-(3-hydroxyphenyl)-N,N-dimethylformamidine + 7
              carbamimidoyl group 0
              formamidine pesticide + 0
              methaneimidamido group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      monocarboxylic acid 18004
                                        formic acid 9094
                                          formamidine 7
                                            (aminomethylidene)amino group 0
                                            N'-(3-hydroxyphenyl)-N,N-dimethylformamidine + 7
                                            carbamimidoyl group 0
                                            formamidine pesticide + 0
                                            methaneimidamido group 0
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