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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tebufenozide
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Accession:CHEBI:38452 term browser browse the term
Definition:A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.
Synonyms:exact_synonym: N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
 related_synonym: 3,5-dimethylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide;   Formula=C22H28N2O2;   InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25);   InChIKey=QYPNKSZPJQQLRK-UHFFFAOYSA-N;   N'-(t-butyl)-N'-(3,5-dimethylbenzoyl)-N-(4-ethylbenzoyl)hydrazine;   SMILES=CCc1ccc(cc1)C(=O)NN(C(=O)c1cc(C)cc(C)c1)C(C)(C)C
 xref: CAS:112410-23-8;   KEGG:C18526
 xref_mesh: MESH:C082026
 xref: PMID:14745824;   PMID:15759403;   PMID:22730139;   PMID:24121094;   PPDB:611;   Patent:CN103553255;   Patent:CN103766364;   Pesticides:tebufenozide;   Reaxys:7822297;   Wikipedia:Tebufenozide


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tebufenozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport		 ISO tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]
ABCB1 protein results in increased transport of tebufenozide		 CTD PMID:26995013 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO tebufenozide results in increased expression of CYP2B6 mRNA CTD PMID:22310298 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO tebufenozide results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Rorb RAR-related orphan receptor B increases activity ISO tebufenozide results in increased activity of RORB protein CTD PMID:20143881 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19880
    role 19850
      biological role 19848
        xenobiotic 18728
          tebufenozide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19880
    subatomic particle 19878
      composite particle 19878
        hadron 19878
          baryon 19878
            nucleon 19878
              atomic nucleus 19878
                atom 19878
                  main group element atom 19817
                    p-block element atom 19817
                      carbon group element atom 19757
                        carbon atom 19754
                          organic molecular entity 19754
                            heteroorganic entity 19512
                              organochalcogen compound 19275
                                organooxygen compound 19191
                                  carbon oxoacid 18658
                                    carboxylic acid 18655
                                      aromatic carboxylic acid 12689
                                        benzoic acids 12666
                                          benzoic acid 5504
                                            benzohydrazide 5
                                              1,2-dibenzoylhydrazine 4
                                                N'-benzoyl-N-(tert-butyl)benzohydrazide 4
                                                  tebufenozide 4
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