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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:muconic acid
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Accession:CHEBI:38407 term browser browse the term
Definition:A hexadienedioic acid with unsaturation at positions 2 and 4.
Synonyms:exact_synonym: hexa-2,4-dienedioic acid
 related_synonym: 1,3-butadiene-1,4-dicarboxylic acid;   2,4-hexadienedioic acid;   Formula=C6H6O4;   InChI=1S/C6H6O4/c7-5(8)3-1-2-4-6(9)10/h1-4H,(H,7,8)(H,9,10);   InChIKey=TXXHDPDFNKHHGW-UHFFFAOYSA-N;   SMILES=[H]C(=CC=C([H])C(O)=O)C(O)=O;   butadiene-1,4-dicarboxylic acid
 alt_id: CHEBI:25424;   CHEBI:36156
 xref: Beilstein:1722248;   Beilstein:1756239;   CAS:505-70-4
 xref_mesh: MESH:C005939
 xref: PMID:23079953;   PMID:23164574;   PMID:24657371;   PMID:24751381
 cyclic_relationship: is_conjugate_acid_of CHEBI:36504


show annotations for term's descendants           Sort by:
muconic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO [CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of muconic acid CTD PMID:15051535 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO [GSTM1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects abundance ISO GSTT1 affects the abundance of muconic acid CTD PMID:10780264 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects abundance ISO NQO1 polymorphism affects the abundance of muconic acid CTD PMID:12798093 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      biological role 19842
        biochemical role 19549
          metabolite 19537
            xenobiotic metabolite 16158
              human xenobiotic metabolite 15778
                muconic acid 5
                  (2E,4Z)-2-hydroxymuconic acid 0
                  (2Z,4E)-2-hydroxymuconic acid 0
                  2-aminomuconic acid + 0
                  3-carboxymethylmuconic acid 0
                  3-sulfomuconic acid 0
                  5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one 0
                  chloromuconic acid + 0
                  cis,cis-muconic acid + 0
                  cis,trans-muconic acid + 0
                  trans,trans-muconic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      monocarboxylic acid 18000
                                        fatty acid 16833
                                          fatty acid derivative 8980
                                            dicarboxylic fatty acid 2652
                                              hexadienedioic acid 5
                                                muconic acid 5
                                                  (2E,4Z)-2-hydroxymuconic acid 0
                                                  (2Z,4E)-2-hydroxymuconic acid 0
                                                  2-aminomuconic acid + 0
                                                  3-carboxymethylmuconic acid 0
                                                  3-sulfomuconic acid 0
                                                  5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one 0
                                                  chloromuconic acid + 0
                                                  cis,cis-muconic acid + 0
                                                  cis,trans-muconic acid + 0
                                                  trans,trans-muconic acid + 0
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