perfluorononanoic acid - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	perfluorononanoic acid	go back to main search page
Accession:	CHEBI:38397	browse the term
Definition:	A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.
Synonyms:	exact_synonym:	heptadecafluorononanoic acid
	related_synonym:	2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluorononanoic acid; Formula=C9HF17O2; Heptadecafluornonansaeure; Heptadekafluornonansaeure; InChI=1S/C9HF17O2/c10-2(11,1(27)28)3(12,13)4(14,15)5(16,17)6(18,19)7(20,21)8(22,23)9(24,25)26/h(H,27,28); InChIKey=UZUFPBIDKMEQEQ-UHFFFAOYSA-N; PFNA; Perfluornonansaeure; SMILES=OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F; perfluoro-n-nonanoic acid; perfluorononan-1-oic acid
	alt_id:	MESH:C584865
	xref:	CAS:375-95-1; Gmelin:317302
	xref_mesh:	MESH:C101816
	xref:	PMID:17093205; PMID:23601780; PMID:24246240; PMID:24295853; Reaxys:1897287; Wikipedia:Perfluorononanoic_acid

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Genes (1603)

perfluorononanoic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase-like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of AADACL2 mRNA

NCBI chr 2:144,123,557...144,144,159

G

alanyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AARS1 mRNA

NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147

G

aminoadipate-semialdehyde synthase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

4-aminobutyrate aminotransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABAT mRNA

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

G

ATP binding cassette subfamily A member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCA1 mRNA

PMID:29112762 PMID:35337807

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCA12 mRNA

NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049

G

ATP binding cassette subfamily A member 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCA6 mRNA

NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530

G

ATP binding cassette subfamily A member 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCA8 mRNA

NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988

G

ATP binding cassette subfamily B member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCB11 mRNA

PMID:29112762 PMID:32588087

NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730

G

ATP-binding cassette, sub-family B member 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCB1B mRNA

NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199

G

ATP binding cassette subfamily B member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCB4 mRNA

NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202

G

ATP binding cassette subfamily C member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCC3 mRNA

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily C member 4

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCC4 mRNA
perfluoro-n-nonanoic acid results in increased expression of ABCC4 mRNA

PMID:23567314 PMID:29112762 PMID:32588087

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

ATP binding cassette subfamily C member 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ABCC9 mRNA

NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356

G

ATP binding cassette subfamily E member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCE1 mRNA

NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489

G

ATP binding cassette subfamily G member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ATP binding cassette subfamily G member 5

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG5 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ABCG5 mRNA

PMID:29112762 PMID:32588087

NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563

G

ATP binding cassette subfamily G member 8

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ABCG8 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ABCG8 mRNA

PMID:29112762 PMID:32588087

NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912

G

actin binding transcription modulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABITRAM mRNA

NCBI chr 5:71,505,848...71,524,224
Ensembl chr 5:71,505,813...71,511,890

G

ABL proto-oncogene 2, non-receptor tyrosine kinase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ABL2 mRNA

NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742

G

acetyl-Coenzyme A acyltransferase 1B

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACAA1B mRNA

NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825

G

acetyl-CoA carboxylase beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACACB mRNA

NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655

G

acyl-CoA dehydrogenase, long chain

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACADL mRNA

NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220

G

acyl-CoA dehydrogenase, short/branched chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACADSB mRNA

NCBI chr 1:186,188,939...186,227,796
Ensembl chr 1:186,188,987...186,230,379

G

acetyl-CoA acetyltransferase 2

multiple interactions
decreases expression

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of ACAT2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of ACAT2 mRNA

PMID:32588087 PMID:33483757

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

angiotensin converting enzyme 2

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ACE2 mRNA

NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977

G

acyl-CoA thioesterase 1

increases expression
multiple interactions
decreases expression

perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA
gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]
perfluoro-n-nonanoic acid results in decreased expression of ACOT1 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of ACOT1 mRNA

PMID:22648072 PMID:28558994 PMID:32588087 PMID:33483757

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

acyl-CoA thioesterase 2

multiple interactions
increases expression
decreases expression

IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]
perfluoro-n-nonanoic acid results in decreased expression of ACOT2 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of ACOT2 mRNA

PMID:22648072 PMID:28558994 PMID:32588087 PMID:33483757

NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245

G

acyl-CoA oxidase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACOX1 mRNA

PMID:23567314 PMID:25543169 PMID:28558994

NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232

G

acyl-CoA oxidase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACOX2 mRNA

NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160

G

acyl-CoA synthetase family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACSL1 mRNA

NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541

G

acyl-CoA synthetase long-chain family member 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase medium-chain family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSM2A mRNA

NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116

G

acyl-CoA synthetase medium-chain family member 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSM5 mRNA

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

acyl-CoA synthetase short-chain family member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACSS2 mRNA

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

actin, beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin related protein 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of ACTR10 mRNA

NCBI chr 6:89,446,141...89,472,350
Ensembl chr 6:89,446,093...89,473,047

G

activin A receptor like type 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ACVRL1 mRNA

NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591

G

adenosine deaminase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADA mRNA

NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088

G

ADAM metallopeptidase domain 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADAM7 mRNA

NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201

G

adhesion G protein-coupled receptor E4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADGRE4P mRNA

NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760

G

adhesion G protein-coupled receptor G1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADGRG1 mRNA

NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108

G

adhesion G protein-coupled receptor G3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADGRG3 mRNA

NCBI chr19:9,972,425...10,001,118
Ensembl chr19:9,972,430...10,001,123

G

alcohol dehydrogenase 4 (class II), pi polypeptide

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADH4 mRNA

NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591

G

alcohol dehydrogenase 6 (class V)

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADH6 mRNA

NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534

G

adenosine A2a receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADORA2A mRNA

NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386

G

adenylosuccinate synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ADSS1 mRNA

NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998

G

androgen-dependent TFPI-regulating protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of ADTRP mRNA

NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826

G

actin filament associated protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

afamin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AFM mRNA

NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870

G

amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGL mRNA

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

alkylglycerol monooxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGMO mRNA

NCBI chr 6:53,986,236...54,317,838
Ensembl chr 6:53,986,292...54,317,623

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGPAT1 mRNA

NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278

G

anterior gradient 2, protein disulphide isomerase family member

increases expression

perfluoro-n-nonanoic acid results in increased expression of AGR2 mRNA

NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371

G

agrin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGRN mRNA

NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003

G

alanine-glyoxylate aminotransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AGXT2 mRNA

NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926

G

AHNAK nucleoprotein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AHNAK2 mRNA

NCBI chr 6:131,830,668...131,876,311
Ensembl chr 6:131,831,454...131,854,463

G

alpha-2-HS-glycoprotein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AHSG mRNA

NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of AIMP2 mRNA

NCBI chr12:10,701,194...10,710,772
Ensembl chr12:10,701,194...10,710,769

G

AT-hook transcription factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKNA mRNA

NCBI chr 5:76,777,415...76,824,380
Ensembl chr 5:76,777,415...76,816,017

G

aldo-keto reductase family 1, member B7

multiple interactions

[PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of AKR1B7 mRNA

NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502

G

aldo-keto reductase family 1, member C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

AKT serine/threonine kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AKT1 protein modified form

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALAD mRNA

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

5'-aminolevulinate synthase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALAS1 mRNA

NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917

G

5'-aminolevulinate synthase 2

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ALAS2 mRNA

NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519

G

aldehyde dehydrogenase 3 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH3A1 mRNA

NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681

G

aldehyde dehydrogenase 3 family, member A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALDH3A2 mRNA

NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281

G

aldehyde dehydrogenase 4 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH4A1 mRNA

NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345

G

aldehyde dehydrogenase 6 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH6A1 mRNA

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

aldehyde dehydrogenase 8 family, member A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDH8A1 mRNA

NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385

G

aldolase, fructose-bisphosphate B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDOB mRNA

NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116

G

aldolase, fructose-bisphosphate C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALDOC mRNA

NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066

G

alkB homolog 8, tRNA methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALKBH8 mRNA

NCBI chr 6:378,779...449,382
Ensembl chr 6:378,100...452,165

G

alpha-kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ALPK2 mRNA

NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258

G

alkaline phosphatase, biomineralization associated

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALPL mRNA

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

alkaline phosphatase, placental

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ALPP mRNA

NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606

G

alpha-1-microglobulin/bikunin precursor

increases expression

perfluoro-n-nonanoic acid results in increased expression of AMBP mRNA

NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331

G

amidohydrolase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AMDHD1 mRNA

NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156

G

anti-Mullerian hormone

increases expression

perfluoro-n-nonanoic acid results in increased expression of AMH mRNA; perfluoro-n-nonanoic acid results in increased expression of AMH protein

NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282

G

amphiphysin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AMPH mRNA

NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315

G

angiogenin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

angiopoietin-like 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANGPTL4 mRNA

PMID:23567314 PMID:32588087

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANK2 mRNA

NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923

G

ankyrin and armadillo repeat containing

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKAR mRNA

NCBI chr 9:48,141,534...48,215,400
Ensembl chr 9:48,141,391...48,215,616

G

ankyrin repeat domain 27

increases expression

perfluoro-n-nonanoic acid results in increased expression of ANKRD27 mRNA

NCBI chr 1:88,251,216...88,303,615
Ensembl chr 1:88,251,226...88,303,615

G

ankyrin repeat domain 40

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKRD40 mRNA

NCBI chr10:79,282,075...79,295,322
Ensembl chr10:79,282,075...79,295,320
Ensembl chr10:79,282,075...79,295,320

G

ankyrin repeat domain 52

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKRD52 mRNA

NCBI chr 7:806,829...820,481
Ensembl chr 7:806,767...820,481

G

ankyrin repeat and sterile alpha motif domain containing 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANKS1B mRNA

NCBI chr 7:24,313,339...25,479,307
Ensembl chr 7:24,312,843...25,477,693

G

anillin, actin binding protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANLN mRNA

NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538

G

acidic nuclear phosphoprotein 32 family member E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANP32E mRNA

NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054

G

alanyl aminopeptidase, membrane

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ANPEP mRNA

NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789

G

annexin A13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ANXA13 mRNA

NCBI chr 7:89,884,356...89,936,907
Ensembl chr 7:89,884,356...89,936,907

G

amine oxidase, copper containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AOC1 mRNA

NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840

G

adaptor-related protein complex 1 associated regulatory protein

increases expression

perfluoro-n-nonanoic acid results in increased expression of AP1AR mRNA

NCBI chr 2:216,276,631...216,309,020
Ensembl chr 2:216,276,631...216,309,013

G

adaptor related protein complex 1 subunit gamma 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AP1G2 mRNA

NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004

G

adaptor related protein complex 5 subunit zeta 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AP5Z1 mRNA

NCBI chr12:12,093,834...12,109,043
Ensembl chr12:12,093,834...12,108,511

G

apoptotic peptidase activating factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APAF1 mRNA

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

aprataxin and PNKP like factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of APLF mRNA

NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633

G

apolipoprotein A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA2 mRNA

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein A4

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein A5

increases expression

perfluoro-n-nonanoic acid results in increased expression of APOA5 mRNA

NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816

G

apolipoprotein C1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APOC1 mRNA

NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375

G

apolipoprotein C3

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of APOC3 mRNA
PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of APOC3 mRNA]

NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583

G

apolipoprotein E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APOE protein

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APPL2 mRNA

NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754

G

adenine phosphoribosyl transferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of APRT mRNA

NCBI chr19:50,626,201...50,628,491
Ensembl chr19:50,626,202...50,628,431

G

aquaporin 3 (Gill blood group)

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

aquaporin 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AQP9 mRNA

NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395

G

ARF guanine nucleotide exchange factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARFGEF2 mRNA

NCBI chr 3:155,547,504...155,633,652
Ensembl chr 3:155,547,538...155,630,856

G

arginase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARG1 mRNA

NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422

G

arginase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARG2 mRNA

NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378

G

Rho GTPase activating protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGAP4 mRNA

NCBI chr X:151,636,071...151,651,528
Ensembl chr X:151,632,454...151,651,128

G

Rho GTPase activating protein 45

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGAP45 mRNA

NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268

G

Rho guanine nucleotide exchange factor 19

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF19 mRNA

NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203

G

Rho/Rac guanine nucleotide exchange factor 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARHGEF2 mRNA

NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355

G

Rho guanine nucleotide exchange factor 38

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARHGEF38 mRNA

NCBI chr 2:221,610,212...221,739,841
Ensembl chr 2:221,613,070...221,740,079

G

Rho guanine nucleotide exchange factor 39

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF39 mRNA

NCBI chr 5:57,752,509...57,756,079
Ensembl chr 5:57,752,509...57,756,109

G

Cdc42 guanine nucleotide exchange factor 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARHGEF9 mRNA

NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513

G

ariadne RBR E3 ubiquitin protein ligase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARIH2 mRNA

NCBI chr 8:109,296,738...109,355,909
Ensembl chr 8:109,296,738...109,355,852

G

arkadia C-terminal like ring finger ubiquitin ligase 2C

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARK2C mRNA

NCBI chr18:70,984,566...71,100,836
Ensembl chr18:70,989,731...71,100,836

G

ARF like GTPase 16

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARL16 mRNA

NCBI chr10:105,737,455...105,739,631
Ensembl chr10:105,737,154...105,739,824

G

ARL6 interacting reticulophagy regulator 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994

G

ARF like GTPase 8A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARL8A mRNA

NCBI chr13:46,585,845...46,594,851
Ensembl chr13:46,585,845...46,594,851

G

cAMP-regulated phosphoprotein 19

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARPP19 mRNA

NCBI chr 8:75,779,640...75,802,474
Ensembl chr 8:75,779,523...75,802,452
Ensembl chr 8:75,779,523...75,802,452

G

arrestin domain containing 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ARRDC3 mRNA

NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978

G

arrestin domain containing 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ARRDC4 mRNA

NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290

G

ADP-ribosyltransferase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

ankyrin repeat and SOCS box-containing 14

increases expression

perfluoro-n-nonanoic acid results in increased expression of ASB14 mRNA

NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135

G

asparagine synthetase (glutamine-hydrolyzing)

increases expression

perfluoro-n-nonanoic acid results in increased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

assembly factor for spindle microtubules

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ASPM mRNA

NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755

G

ATPase family, AAA domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATAD2 mRNA

NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738

G

ATPase family, AAA domain containing 3A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATAD3A mRNA

NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482

G

ATPase family, AAA domain containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATAD5 mRNA

NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845

G

activating transcription factor 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATF4 mRNA

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

autophagy related 4A, cysteine peptidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATG4A mRNA

NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268

G

atonal bHLH transcription factor 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATOH8 mRNA

NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168

G

ATPase Na+/K+ transporting subunit alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP1A1 mRNA

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATPase Na+/K+ transporting subunit alpha 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP1A2 mRNA

NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544

G

ATPase plasma membrane Ca2+ transporting 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATP2B1 mRNA

NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295

G

ATPase plasma membrane Ca2+ transporting 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP2B2 mRNA

NCBI chr 4:146,894,602...147,208,060
Ensembl chr 4:146,896,332...147,140,665

G

ATPase plasma membrane Ca2+ transporting 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ATP2B4 mRNA

NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246

G

ATP synthase inhibitory factor subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP5IF1 mRNA

NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668

G

ATPase, H+ transporting V0 subunit e2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATP6V0E2 mRNA

NCBI chr 4:77,484,868...77,488,016
Ensembl chr 4:77,482,226...77,488,777

G

ataxin 2-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ATXN2L mRNA

NCBI chr 1:181,078,293...181,090,079
Ensembl chr 1:181,078,288...181,089,686

G

aurora kinase A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AURKA mRNA

NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390

G

aurora kinase B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of AURKB mRNA

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

axin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of AXIN1 mRNA

NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615

G

beta-1,4-galactosyltransferase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of B4GALT5 mRNA

NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074

G

bile acid CoA:amino acid N-acyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BAAT mRNA

NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

BAI1-associated protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BAIAP3 mRNA

NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019

G

BCL2 associated X, apoptosis regulator

increases expression

perfluoro-n-nonanoic acid results in increased expression of BAX mRNA

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

butyrylcholinesterase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BCHE mRNA

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of BCL2 mRNA; perfluoro-n-nonanoic acid results in decreased expression of BCL2 protein
perfluoro-n-nonanoic acid results in increased expression of BCL2 mRNA

PMID:19196829 PMID:19646514 PMID:19878704 PMID:32588087

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

BCL9 like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BCL9L mRNA

NCBI chr 8:44,811,977...44,840,611
Ensembl chr 8:44,811,977...44,840,611

G

BCLAF1 and THRAP3 family member 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CXORF23 mRNA

NCBI chr X:35,257,228...35,328,883
Ensembl chr X:35,263,576...35,328,816

G

3-hydroxybutyrate dehydrogenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BDH1 mRNA

NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671

G

brain-derived neurotrophic factor

multiple interactions

[[Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides] affects the susceptibility to perfluoro-n-nonanoic acid] which results in decreased expression of BDNF protein

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

G

baculoviral IAP repeat-containing 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of BIRC3 mRNA

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BIRC5 mRNA

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

biogenesis of lysosomal organelles complex-1, subunit 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of BLOC1S2 mRNA

NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653

G

bridge-like lipid transfer protein family member 3A

increases expression

perfluoro-n-nonanoic acid results in increased expression of BLTP3A mRNA

NCBI chr20:5,910,261...5,954,641
Ensembl chr20:5,910,260...5,952,404

G

bone morphogenetic protein 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BMP4 mRNA

NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306

G

basonuclin zinc finger protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BNC1 mRNA

NCBI chr 1:135,917,676...135,943,333
Ensembl chr 1:135,917,687...135,943,333

G

BCL2 interacting protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

biorientation of chromosomes in cell division 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of BOD1 mRNA

NCBI chr10:15,993,454...15,999,795
Ensembl chr10:15,993,454...15,999,787

G

bora, aurora kinase A activator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BORA mRNA

NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322

G

biphenyl hydrolase like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BPHL mRNA

NCBI chr17:30,800,939...30,837,277
Ensembl chr17:30,799,629...30,837,288

G

BRF2 general transcription factor 3B subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of BRF2 mRNA

NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059

G

BMP/retinoic acid inducible neural specific 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRINP1 mRNA

NCBI chr 5:82,348,501...82,550,506
Ensembl chr 5:82,348,930...82,493,150

G

BMP/retinoic acid inducible neural specific 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRINP3 mRNA

NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770

G

bromodomain and PHD finger containing, 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BRPF1 mRNA

NCBI chr 4:146,456,325...146,472,781
Ensembl chr 4:146,456,318...146,472,649

G

BUB1 mitotic checkpoint serine/threonine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of BUB1 mRNA

NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650

G

bystin-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of BYSL mRNA

NCBI chr 9:13,382,806...13,392,557
Ensembl chr 9:13,382,557...13,394,339

G

similar to human chromosome 1 open reading frame 226

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1ORF226 mRNA

NCBI chr13:82,530,589...82,538,676
Ensembl chr13:82,530,577...82,820,949

G

C1q and TNF related 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1QTNF1 mRNA

NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660

G

C1q and TNF related 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C1QTNF6 mRNA

NCBI chr 7:110,077,867...110,084,584
Ensembl chr 7:110,077,878...110,084,412

G

complement C3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C3 mRNA

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement component 4 binding protein, beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C4BPB mRNA

NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817

G

complement C8 alpha chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C8A mRNA

NCBI chr 5:119,583,168...119,637,675
Ensembl chr 5:119,583,174...119,637,754

G

similar to human chromosome 11 open reading frame 54

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 3 open reading frame 18

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C3ORF18 mRNA

NCBI chr 8:108,012,638...108,022,050
Ensembl chr 8:108,012,638...108,022,461

G

complement C9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C9 mRNA

NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338

G

similar to human chromosome 2 open reading frame 72

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of C2ORF72 mRNA

NCBI chr 9:86,691,767...86,699,920
Ensembl chr 9:86,691,867...86,698,185

G

colon adenocarcinoma hypermethylated

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAHM mRNA

NCBI chr 1:50,385,803...50,386,959

G

calcitonin receptor like receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of CALCRL mRNA

NCBI chr 3:69,428,348...69,525,910
Ensembl chr 3:69,430,120...69,525,910

G

calmodulin-like 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CALML4 mRNA

NCBI chr 8:63,323,426...63,335,234
Ensembl chr 8:63,323,351...63,335,234

G

calmodulin regulated spectrin-associated protein family, member 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAMSAP2 mRNA

NCBI chr13:47,723,251...47,802,606
Ensembl chr13:47,723,121...47,802,597

G

calpain 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAPN10 mRNA

NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494

G

calpain 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of CAPN5 mRNA

NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923

G

carbonic anhydrase 9

increases expression

perfluoro-n-nonanoic acid results in increased expression of CA9 mRNA

NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838

G

caspase recruitment domain family, member 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CARD11 mRNA

NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112

G

caspase recruitment domain family, member 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CARD6 mRNA

NCBI chr 2:54,194,343...54,206,902
Ensembl chr 2:54,195,739...54,206,846

G

cysteinyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CARS1 mRNA

NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941

G

caspase 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CASP14 mRNA

NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405

G

caspase 3

decreases expression
decreases cleavage

perfluoro-n-nonanoic acid results in decreased expression of CASP3 protein
perfluoro-n-nonanoic acid results in decreased cleavage of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 8

decreases expression
increases activity

perfluoro-n-nonanoic acid results in decreased expression of CASP8 protein
perfluoro-n-nonanoic acid results in increased activity of CASP8 protein

PMID:19646514 PMID:19878704

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

cation channel sperm associated auxiliary subunit gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of CATSPERG mRNA

NCBI chr 1:84,488,728...84,519,495
Ensembl chr 1:84,488,730...84,519,559

G

caveolae associated protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAVIN1 mRNA

NCBI chr10:85,884,100...85,896,136
Ensembl chr10:85,889,036...85,896,120

G

caveolae associated protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CAVIN3 mRNA

NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161

G

Cbl proto-oncogene B

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of CBLB mRNA
perfluoro-n-nonanoic acid results in decreased expression of CBLB mRNA

PMID:25812627 PMID:32588087

NCBI chr11:48,589,878...48,756,940
Ensembl chr11:48,592,703...48,756,839

G

chromobox 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CBX4 mRNA

NCBI chr10:104,337,140...104,343,210
Ensembl chr10:104,336,876...104,356,706

G

cell cycle and apoptosis regulator 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCAR2 mRNA

NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636

G

coiled-coil domain containing 107

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCDC107 mRNA

NCBI chr 5:57,749,502...57,752,920
Ensembl chr 5:57,748,999...57,752,918

G

coiled-coil domain containing 113

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP263 mRNA

NCBI chr19:9,497,000...9,516,917
Ensembl chr19:9,496,886...9,516,923

G

coiled-coil domain containing 178

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC178 mRNA

NCBI chr18:13,074,834...13,472,732
Ensembl chr18:13,075,468...13,472,160

G

coiled-coil domain containing 59

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC59 mRNA

NCBI chr 7:41,142,760...41,149,143
Ensembl chr 7:41,142,760...41,149,143

G

coiled-coil domain containing 69

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCDC69 mRNA

NCBI chr10:39,173,282...39,200,358
Ensembl chr10:39,173,282...39,199,878

G

coiled-coil domain containing 85C

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCDC85C mRNA

NCBI chr 6:127,113,440...127,184,328
Ensembl chr 6:127,113,442...127,184,371

G

C-C motif chemokine ligand 20

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of CCL20 mRNA
perfluoro-n-nonanoic acid results in decreased expression of CCL20 mRNA

PMID:32588087 PMID:38568856

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

cellular communication network factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCN2 mRNA

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cellular communication network factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of WISP1 mRNA

NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248

G

cyclin A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNA2 mRNA

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNB1 mRNA

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCND2 mRNA

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin F

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CCNF mRNA

NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101

G

cell cycle progression 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CCPG1 mRNA

NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430

G

CD14 molecule

increases expression

perfluoro-n-nonanoic acid results in increased expression of CD14 mRNA

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

Cd200 molecule

increases expression

perfluoro-n-nonanoic acid results in increased expression of CD200 mRNA

NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648

G

CD22 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD22 mRNA

NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322

G

CD24 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD24 mRNA

NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662

G

CD36 molecule

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CD36 mRNA
PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CD36 mRNA]

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD3 epsilon subunit of T-cell receptor complex

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD3E mRNA

NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022

G

CD40 molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CD40 protein

NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534

G

cell division cycle 20

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

cell division cycle 20B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC20B mRNA

NCBI chr 2:44,688,349...44,738,056

G

cell division cycle 25C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC25C mRNA

NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185

G

cell division cycle 37-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDC37L1 mRNA

NCBI chr 1:226,705,019...226,733,994
Ensembl chr 1:226,705,003...226,761,175

G

CDC42 binding protein kinase beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDC42BPB mRNA

NCBI chr 6:130,333,712...130,416,631
Ensembl chr 6:130,333,712...130,416,377

G

CDC42 effector protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDC42EP1 mRNA

NCBI chr 7:110,395,287...110,403,203
Ensembl chr 7:110,395,332...110,403,200

G

cell division cycle associated 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDCA3 mRNA

NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799

G

cadherin 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDH13 mRNA

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cyclin-dependent kinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin dependent kinase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK2 mRNA

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase 2 associated protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDK2AP2 mRNA

NCBI chr 1:201,391,056...201,393,137
Ensembl chr 1:201,391,466...201,393,137

G

cyclin-dependent kinase inhibitor 2C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CDKN2C mRNA

PMID:25812627 PMID:32588087

NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278

G

cyclin dependent kinase inhibitor 2D

increases expression

perfluoro-n-nonanoic acid results in increased expression of CDKN2D mRNA

NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674

G

CCAAT/enhancer binding protein gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of CEBPG mRNA

NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569

G

carboxyl ester lipase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEL mRNA

NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035

G

centromere protein A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPA mRNA

NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675

G

centromere protein E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centromere protein I

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CENPI mRNA

NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657

G

centrosomal protein 131

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP131 mRNA

NCBI chr10:105,346,015...105,370,380
Ensembl chr10:105,346,015...105,370,380

G

centrosomal protein 152

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP152 mRNA

NCBI chr 3:112,803,185...112,878,298
Ensembl chr 3:112,810,425...112,878,458
Ensembl chr 3:112,810,425...112,878,458

G

centrosomal protein 290

increases expression

perfluoro-n-nonanoic acid results in increased expression of CEP290 mRNA

NCBI chr 7:35,310,071...35,399,388
Ensembl chr 7:35,310,199...35,399,392

G

centrosomal protein 78

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CEP78 mRNA

PMID:25812627 PMID:32588087

NCBI chr 1:213,246,183...213,275,275
Ensembl chr 1:213,246,187...213,275,181

G

ceramide synthase 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of CERS6 mRNA

NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848

G

carboxylesterase 2C

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CES2C mRNA

NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790

G

centrin 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CETN2 mRNA

NCBI chr X:150,769,944...150,774,833
Ensembl chr X:150,769,953...150,774,919

G

cilia and flagella associated protein 68

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP68 mRNA

NCBI chr 8:51,107,663...51,113,192
Ensembl chr 8:51,107,721...51,113,420

G

cilia and flagella associated protein 97

increases expression

perfluoro-n-nonanoic acid results in increased expression of CFAP97 mRNA

NCBI chr16:46,086,104...46,135,194
Ensembl chr16:46,086,111...46,125,933

G

complement factor H-related 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CFHR4 mRNA

NCBI chr13:51,422,592...51,491,476
Ensembl chr13:51,422,592...51,491,502

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

coiled-coil-helix-coiled-coil-helix domain containing 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHCHD10 mRNA

NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763

G

charged multivesicular body protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHMP3 mRNA

NCBI chr 4:103,576,453...103,622,566
Ensembl chr 4:103,576,515...103,623,959

G

chimerin 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHN2 mRNA

NCBI chr 4:83,148,616...83,407,711
Ensembl chr 4:83,147,983...83,407,709

G

carbohydrate sulfotransferase 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of CHST11 mRNA

NCBI chr 7:20,524,535...20,743,008
Ensembl chr 7:20,528,100...20,743,111

G

carbohydrate sulfotransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHST2 mRNA

NCBI chr 8:95,960,067...95,966,312
Ensembl chr 8:95,959,826...95,966,955

G

carbohydrate sulfotransferase 9

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CHST9 mRNA

NCBI chr18:6,576,391...6,851,078
Ensembl chr18:6,577,348...6,850,868

G

cell death-inducing DFFA-like effector a

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CIDEA mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CIDEA mRNA

PMID:25812627 PMID:33483757

NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481

G

cell death-inducing DFFA-like effector b

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CIDEB mRNA

NCBI chr15:29,252,208...29,256,482
Ensembl chr15:29,252,213...29,256,605

G

cell death-inducing DFFA-like effector c

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CIDEC mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CIDEC mRNA; PPARA gene mutant form inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CIDEC mRNA]

PMID:28049043 PMID:33483757

NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173

G

class II, major histocompatibility complex, transactivator

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CIITA mRNA

NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440

G

CDC28 protein kinase regulatory subunit 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

CLK4-associating serine/arginine rich protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLASRP mRNA

NCBI chr 1:79,232,260...79,256,462
Ensembl chr 1:79,232,261...79,256,354

G

claudin 14

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLDN14 mRNA

NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171

G

claudin 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLDN8 mRNA

NCBI chr11:27,875,857...27,878,106
Ensembl chr11:27,875,692...27,878,513

G

calmegin

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLGN mRNA

NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758

G

CAP-GLY domain containing linker protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLIP1 mRNA

NCBI chr12:32,910,932...33,017,891
Ensembl chr12:32,910,977...33,017,884

G

CAP-GLY domain containing linker protein family, member 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLIP4 mRNA

NCBI chr 6:23,616,280...23,697,625
NCBI chr 6:23,718,580...23,729,231
NCBI chr 6:23,597,729...23,601,000
Ensembl chr 6:23,616,281...23,677,874

G

clarin 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLRN3 mRNA

NCBI chr 1:190,319,025...190,334,648
Ensembl chr 1:190,319,026...190,334,648

G

claspin

increases expression

perfluoro-n-nonanoic acid results in increased expression of CLSPN mRNA

NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034

G

clustered mitochondria homolog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLUH mRNA

PMID:25812627 PMID:38568856

NCBI chr10:59,509,580...59,531,345
Ensembl chr10:59,509,726...59,531,345

G

citramalyl-CoA lyase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CLYBL mRNA

NCBI chr15:99,283,644...99,505,697
Ensembl chr15:99,283,650...99,505,695

G

chemerin chemokine-like receptor 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CMKLR2 mRNA

NCBI chr 9:64,583,310...64,617,883
Ensembl chr 9:64,585,594...64,586,655

G

cms1 ribosomal small subunit homolog

increases expression

perfluoro-n-nonanoic acid results in increased expression of CMSS1 mRNA

NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624

G

CKLF-like MARVEL transmembrane domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CMTM1 mRNA

NCBI chr19:651,641...661,184
Ensembl chr19:651,644...661,184

G

cyclic nucleotide binding domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CNBD1 mRNA

NCBI chr 5:32,234,003...32,606,765
Ensembl chr 5:32,329,368...32,606,705

G

connector enhancer of kinase suppressor of Ras 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CNKSR2 mRNA

NCBI chr X:36,908,135...37,148,337
Ensembl chr X:36,907,850...37,150,555

G

2',3'-cyclic nucleotide 3' phosphodiesterase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CNP mRNA

NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720

G

collagen type XIV alpha 1 chain

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of COL14A1 mRNA

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

coenzyme Q10A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of COQ10A mRNA

NCBI chr 7:792,089...798,392
Ensembl chr 7:792,089...800,161

G

cytochrome c oxidase assembly factor COX19

increases expression

perfluoro-n-nonanoic acid results in increased expression of COX19 mRNA

NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014

G

cytoplasmic polyadenylation element binding protein 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of CPEB4 mRNA

NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603

G

cadherin-like and PC-esterase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPED1 mRNA

NCBI chr 4:50,516,712...50,789,651
Ensembl chr 4:50,516,819...50,788,674

G

carboxypeptidase M

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPM mRNA

NCBI chr 7:53,225,647...53,286,220
Ensembl chr 7:53,225,696...53,286,220

G

carboxypeptidase N subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPN1 mRNA

NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465

G

carbamoyl-phosphate synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPS1 mRNA

NCBI chr 9:68,614,153...68,737,037
Ensembl chr 9:68,614,153...68,737,033

G

carnitine palmitoyltransferase 1A

multiple interactions
increases expression
decreases expression

gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; prolinedithiocarbamate inhibits the reaction [TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; TNF protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]
perfluoro-n-nonanoic acid results in decreased expression of CPT1A mRNA

PMID:22648072 PMID:23567314 PMID:32588087 PMID:38568856

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1B

affects expression
multiple interactions
increases expression

perfluoro-n-nonanoic acid affects the expression of CPT1B mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CPT1B mRNA
perfluoro-n-nonanoic acid results in increased expression of CPT1B mRNA

PMID:23567314 PMID:33483757 PMID:35337807

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

carnitine palmitoyltransferase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

carboxypeptidase Z

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CPZ mRNA

NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945

G

carnitine O-acetyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 3-like 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CREB3L3 mRNA

PMID:28558994 PMID:32588087

NCBI chr 7:8,622,614...8,631,053
Ensembl chr 7:8,622,614...8,631,048

G

CREB3 regulatory factor

increases expression

perfluoro-n-nonanoic acid results in increased expression of CREBRF mRNA

NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999

G

cysteine-rich with EGF-like domains 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRELD2 mRNA

NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543

G

carnitine O-octanoyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CROT mRNA

NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109

G

C-reactive protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRP mRNA

NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178

G

CREB regulated transcription coactivator 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CRTC3 mRNA

NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500

G

crystallin, beta A1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRYBA1 mRNA

NCBI chr10:62,608,373...62,614,726
Ensembl chr10:62,608,383...62,614,726

G

crystallin, mu

increases expression

perfluoro-n-nonanoic acid results in increased expression of CRYM mRNA

NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633

G

colony stimulating factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CSF1 protein

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

cysteine and serine rich nuclear protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSRNP2 mRNA

NCBI chr 7:131,594,232...131,610,075
Ensembl chr 7:131,594,232...131,610,075

G

cysteine and glycine rich protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

cystatin A

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSTA mRNA

NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488

G

cystatin B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CSTB protein

NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526

G

cystatin-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CSTL1 mRNA

NCBI chr 3:136,199,914...136,204,912
Ensembl chr 3:136,199,914...136,204,912

G

C-terminal binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTBP1 mRNA

NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821

G

cystathionine gamma-lyase

increases expression

perfluoro-n-nonanoic acid results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

cap binding complex dependent translation initiation factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTIF mRNA

NCBI chr18:69,056,151...69,327,454
Ensembl chr18:69,059,519...69,327,385

G

CTP synthase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTPS2 mRNA

NCBI chr X:31,645,873...31,786,733
Ensembl chr X:31,645,873...31,786,733

G

cathepsin W

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CTSW mRNA

NCBI chr 1:202,772,395...202,777,021
Ensembl chr 1:202,772,572...202,775,964

G

C-X-C motif chemokine ligand 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CXCL10 mRNA

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 16

increases expression

perfluoro-n-nonanoic acid results in increased expression of CXCL16 mRNA

NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592

G

CXXC finger protein 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CXXC5 mRNA

NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673

G

cytochrome b561 family, member A3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYB561A3 mRNA

NCBI chr 1:207,216,185...207,237,575
Ensembl chr 1:207,226,230...207,237,571

G

cytochrome b5 type B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYB5B mRNA

NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249

G

cytoglobin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYGB mRNA

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP11A1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of CYP11A1 protein

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 17, subfamily a, polypeptide 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYP17A1 mRNA

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 19, subfamily a, polypeptide 1

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in increased expression of CYP19A1 mRNA

NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 27, subfamily a, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP27A1 mRNA

PMID:29112762 PMID:32588087

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily b, polypeptide 3

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CYP2B6 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CYP2B10 mRNA; [PPARA gene mutant form results in increased susceptibility to perfluoro-n-nonanoic acid] which results in increased expression of CYP2B10 mRNA
perfluoro-n-nonanoic acid results in increased expression of CYP2B10 mRNA

PMID:23567314 PMID:25543169 PMID:25949234 PMID:28558994 PMID:33483757

NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143

G

cytochrome P450, family 2, subfamily c, polypeptide 24

increases expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of CYP2C55 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in increased expression of CYP2C55 mRNA

PMID:28558994 PMID:33483757

NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238

G

cytochrome P450, family 2, subfamily e, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP2E1 mRNA

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 39, subfamily a, polypeptide 1

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of CYP39A1 mRNA

NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYP3A4 mRNA

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily x, polypeptide 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP4X1 mRNA

NCBI chr 5:128,651,681...128,683,338
Ensembl chr 5:128,651,776...128,682,779

G

cytochrome P450 family 7 subfamily A member 1

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of CYP7A1 mRNA
[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of CYP7A1 mRNA

PMID:23567314 PMID:29112762 PMID:32588087 PMID:33483757

NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688

G

cytochrome P450 family 7 subfamily B member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

cytochrome P450 family 8 subfamily B member 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of CYP8B1 mRNA

PMID:29112762 PMID:32588087

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

cytokine like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of CYTL1 mRNA

NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886

G

DAB adaptor protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DAB1 mRNA

NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552

G

D-amino-acid oxidase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DAO mRNA

NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741

G

aspartyl-tRNA synthetase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DARS1 mRNA

NCBI chr13:39,857,936...39,913,055
Ensembl chr13:39,857,936...39,913,116

G

diazepam binding inhibitor

increases expression

perfluoro-n-nonanoic acid results in increased expression of DBI mRNA

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

G

drebrin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DBN1 mRNA

NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984

G

D-box binding PAR bZIP transcription factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

DDB1 and CUL4 associated factor 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCAF11 mRNA

NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669

G

discoidin, CUB and LCCL domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DCBLD1 mRNA

NCBI chr20:31,618,556...31,711,697
Ensembl chr20:31,618,542...31,711,692

G

dachsous cadherin-related 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCHS1 mRNA

NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808

G

deoxycytidine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCK mRNA

NCBI chr14:19,305,218...19,326,247
Ensembl chr14:19,305,218...19,326,247

G

doublecortin-like kinase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DCLK1 mRNA

NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956

G

dicarbonyl and L-xylulose reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DCXR mRNA

NCBI chr10:106,006,404...106,008,293

G

DNA-damage inducible transcript 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDIT3 mRNA

PMID:23567314 PMID:32588087

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDIT4 mRNA

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

DEAD/H-box helicase 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX11 mRNA

NCBI chr 9:105,833,234...105,862,844
Ensembl chr 9:105,833,504...105,862,550

G

DExD-box helicase 21

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX21 mRNA

NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543

G

DExD-box helicase 50

increases expression

perfluoro-n-nonanoic acid results in increased expression of DDX50 mRNA

NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152

G

DEAD-box helicase 54

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DDX54 mRNA

NCBI chr12:35,934,713...35,949,956
Ensembl chr12:35,934,716...35,972,523

G

2,4-dienoyl-CoA reductase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

defensin beta 4

multiple interactions

[Dietary Fats co-treated with perfluoro-n-nonanoic acid] results in decreased expression of DEFB7 mRNA

NCBI chr16:70,650,472...70,653,665
Ensembl chr16:70,650,472...70,653,665

G

DENN domain containing 1C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DENND1C mRNA

NCBI chr 9:1,904,040...1,916,329
Ensembl chr 9:1,904,045...1,916,187

G

DEP domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC1 mRNA

NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951

G

DEP domain containing 1B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC1B mRNA

NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779

G

DEP domain containing 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DEPDC7 mRNA

NCBI chr 3:91,099,111...91,121,152
Ensembl chr 3:91,099,835...91,121,124

G

desumoylating isopeptidase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DESI1 mRNA

NCBI chr 7:113,519,974...113,542,834
Ensembl chr 7:113,519,980...113,542,845

G

diacylglycerol O-acyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

DiGeorge syndrome critical region gene 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGCR6 mRNA

NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823

G

diacylglycerol kinase, beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of DGKB mRNA

NCBI chr 6:54,640,948...55,397,210
Ensembl chr 6:54,641,614...55,397,043

G

diacylglycerol kinase, eta

increases expression

perfluoro-n-nonanoic acid results in increased expression of DGKH mRNA

NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706

G

D-glutamate cyclase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DGLUCY mRNA

NCBI chr 6:120,055,480...120,130,910
Ensembl chr 6:120,055,460...120,130,910

G

7-dehydrocholesterol reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dihydroorotate dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHODH mRNA

NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654

G

dehydrogenase/reductase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHRS1 mRNA

NCBI chr15:29,236,522...29,243,807
Ensembl chr15:29,236,522...29,243,838

G

dehydrogenase/reductase 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of DHRS4 mRNA

NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127

G

dehydrogenase E1 and transketolase domain containing 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DHTKD1 mRNA

NCBI chr17:72,355,201...72,406,725
Ensembl chr17:72,355,201...72,406,723

G

iodothyronine deiodinase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DIO1 mRNA

NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970

G

dyskerin pseudouridine synthase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DKC1 mRNA

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DKK1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of DKK1 protein

PMID:32588087 PMID:32916415

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

discs large MAGUK scaffold protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DLG2 mRNA

NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475

G

discs large MAGUK scaffold protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DLG3 mRNA

NCBI chr X:65,859,653...65,911,887
Ensembl chr X:65,860,172...65,910,322

G

dimethylglycine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DMGDH mRNA

NCBI chr 2:24,912,600...24,987,533
Ensembl chr 2:24,912,578...24,987,528

G

dynein, axonemal, assembly factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAAF5 mRNA

NCBI chr12:15,453,636...15,492,722
Ensembl chr12:15,453,636...15,492,739

G

dynein, axonemal, heavy chain 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAH6 mRNA

NCBI chr 4:105,064,123...105,284,361
Ensembl chr 4:105,064,125...105,284,376

G

dynein axonemal intermediate chain 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAI7 mRNA

NCBI chr 4:178,143,499...178,179,871
Ensembl chr 4:178,143,500...178,179,980

G

DnaJ heat shock protein family (Hsp40) member A3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJA3 mRNA

NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161

G

DnaJ heat shock protein family (Hsp40) member B5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJB5 mRNA

NCBI chr 5:57,176,840...57,186,067
Ensembl chr 5:57,176,845...57,185,490

G

DnaJ heat shock protein family (Hsp40) member B7

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJB7 mRNA

NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537

G

DnaJ heat shock protein family (Hsp40) member C2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DNAJC2 mRNA

NCBI chr 4:13,270,239...13,297,438
Ensembl chr 4:13,270,191...13,297,431

G

DnaJ heat shock protein family (Hsp40) member C24

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJC24 mRNA

NCBI chr 3:92,450,631...92,486,004
Ensembl chr 3:92,450,639...92,485,901

G

DnaJ heat shock protein family (Hsp40) member C3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DNAJC3 mRNA

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

dedicator of cytokinesis 11

increases expression

perfluoro-n-nonanoic acid results in increased expression of DOCK11 mRNA

NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854

G

deoxyhypusine hydroxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DOHH mRNA

NCBI chr 7:8,321,466...8,326,305
Ensembl chr 7:8,321,466...8,326,289

G

dolichyl-phosphate N-acetylglucosaminephosphotransferase 1

affects methylation

perfluoro-n-nonanoic acid affects the methylation of DPAGT1 gene

NCBI chr 8:44,664,055...44,671,102
Ensembl chr 8:44,664,071...44,671,087

G

diphthamide biosynthesis 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of DPH2 mRNA

NCBI chr 5:131,428,434...131,431,394
Ensembl chr 5:131,428,268...131,431,395

G

diphthamide biosynthesis 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of DPH3 mRNA

NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265

G

dipeptidylpeptidase 4

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of DPP4 mRNA
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] affects the expression of DPP4 mRNA

PMID:32588087 PMID:36270329

NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901

G

dihydropyrimidine dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DPYD mRNA

NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982

G

dihydropyrimidinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DPYS mRNA

NCBI chr 7:70,822,648...70,929,255
Ensembl chr 7:70,835,789...70,929,231

G

dopamine receptor D2

multiple interactions

[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA

NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875

G

dopamine receptor D5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DRD5 mRNA

NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774

G

desmocollin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DSC1 mRNA

NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494

G

dermatan sulfate epimerase-like

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DSEL mRNA

NCBI chr13:186,413...192,592
Ensembl chr13:175,805...192,647

G

D-aminoacyl-tRNA deacylase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of DTD1 mRNA

NCBI chr 3:131,995,870...132,158,646
Ensembl chr 3:131,995,861...132,158,659

G

dihydrouridine synthase 3-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUS3L mRNA

NCBI chr 9:1,593,491...1,598,663
Ensembl chr 9:1,594,123...1,598,655

G

dihydrouridine synthase 4-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUS4L mRNA

NCBI chr 6:48,228,111...48,242,553
Ensembl chr 6:48,228,111...48,242,449

G

dual specificity phosphatase 10

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP10 mRNA

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 12

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP12 mRNA

NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285

G

dual specificity phosphatase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of DUSP5 mRNA

NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818

G

dishevelled segment polarity protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DVL1 mRNA

NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664

G

dishevelled segment polarity protein 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of DVL3 mRNA

NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462

G

E2F transcription factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of E2F5 mRNA

NCBI chr 2:86,997,331...87,012,908
Ensembl chr 2:86,997,332...87,012,990

G

E2F transcription factor 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of E2F8 mRNA

NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098

G

EBP, cholestenol delta-isomerase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

enoyl-CoA hydratase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

enoyl CoA hydratase domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ECHDC2 mRNA

NCBI chr 5:122,915,874...122,934,860
Ensembl chr 5:122,916,134...122,934,859

G

enoyl-CoA delta isomerase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

enoyl-CoA delta isomerase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ECI2 mRNA

NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781

G

epithelial cell transforming 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ECT2 mRNA

NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911

G

eukaryotic translation elongation factor 1 alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1A1 mRNA

NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839

G

eukaryotic translation elongation factor 1 delta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1D mRNA

NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799

G

eukaryotic translation elongation factor 1 gamma

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF1G mRNA

NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382

G

eukaryotic translation elongation factor 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EEF2 mRNA

NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183

G

eukaryotic elongation factor 2 lysine methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of EEF2KMT mRNA

NCBI chr10:10,336,933...10,349,463
Ensembl chr10:10,336,974...10,347,039

G

EF-hand calcium binding domain 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of EFCAB2 mRNA

NCBI chr13:90,152,002...90,237,918
Ensembl chr13:90,152,185...90,238,218

G

ephrin A4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EFNA4 mRNA

NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979

G

EFR3 homolog B

increases expression

perfluoro-n-nonanoic acid results in increased expression of EFR3B mRNA

NCBI chr 6:26,947,436...27,021,113
Ensembl chr 6:26,948,540...27,020,933

G

epidermal growth factor receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of EHHADH mRNA
perfluoro-n-nonanoic acid results in decreased expression of EHHADH mRNA

PMID:23567314 PMID:25543169 PMID:28558994 PMID:32588087

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 2 subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF2S2 mRNA

NCBI chr 3:143,374,652...143,395,460
Ensembl chr 3:143,373,686...143,395,432

G

eukaryotic translation initiation factor 3, subunit D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EIF3D mRNA

NCBI chr 7:109,539,795...109,552,184
Ensembl chr 7:109,539,356...109,552,206

G

eukaryotic translation initiation factor 4E binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF4EBP1 mRNA

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

eukaryotic translation initiation factor 4E binding protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF4EBP3 mRNA

NCBI chr18:28,263,089...28,268,033
Ensembl chr18:28,162,311...28,268,024

G

eukaryotic translation initiation factor 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF5 mRNA

NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656

G

eukaryotic translation initiation factor 6

increases expression

perfluoro-n-nonanoic acid results in increased expression of EIF6 mRNA

NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401

G

E74 like ETS transcription factor 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of ELF3 mRNA

NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481

G

engulfment and cell motility 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ELMO1 mRNA

NCBI chr17:44,286,495...44,822,668
Ensembl chr17:44,286,485...44,822,788

G

ELOVL fatty acid elongase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ELOVL2 mRNA

NCBI chr17:23,544,598...23,584,855
Ensembl chr17:23,544,568...23,584,848

G

ELOVL fatty acid elongase 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

Emx2 opposite strand/antisense RNA

increases expression

perfluoro-n-nonanoic acid results in increased expression of EMX2OS mRNA

NCBI chr 1:258,569,637...258,626,810

G

endonuclease G

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ENDOG mRNA

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

glutamyl aminopeptidase

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of ENPEP mRNA

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

ectonucleoside triphosphate diphosphohydrolase 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ENTPD5 mRNA

NCBI chr 6:104,019,095...104,055,311
Ensembl chr 6:104,019,185...104,055,530

G

ectonucleoside triphosphate diphosphohydrolase 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ENTPD7 mRNA

NCBI chr 1:242,559,365...242,601,044
Ensembl chr 1:242,559,365...242,601,447

G

ectonucleoside triphosphate diphosphohydrolase 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of ENTPD8 mRNA

NCBI chr 3:7,885,277...7,895,517
Ensembl chr 3:7,889,909...7,895,296

G

erythrocyte membrane protein band 4.1-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPB41L1 mRNA

NCBI chr 3:144,929,195...145,052,723
Ensembl chr 3:144,984,640...145,052,721

G

erythrocyte membrane protein band 4.1-like 3

affects methylation

perfluoro-n-nonanoic acid affects the methylation of EPB41L3 gene

NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607

G

epithelial cell adhesion molecule

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPCAM mRNA

NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127

G

Eph receptor A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHA1 mRNA

NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846

G

Eph receptor A2

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPHA2 mRNA

NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117

G

EPH receptor A5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPHA5 mRNA

NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317

G

EPH receptor B4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHB4 mRNA

NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314

G

epoxide hydrolase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

Epsin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPN1 mRNA

NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874

G

elongin BC and polycomb repressive complex 2 associated protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EPOP mRNA

NCBI chr10:82,624,392...82,625,912
Ensembl chr10:82,624,392...82,625,912

G

glutamyl-prolyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EPRS1 mRNA

NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966

G

erb-b2 receptor tyrosine kinase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERBB3 mRNA

NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525

G

epiregulin

increases expression

perfluoro-n-nonanoic acid results in increased expression of EREG mRNA

NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062

G

ergosterol biosynthesis 28 homolog

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

glutamate-rich 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERICH2 mRNA

NCBI chr 3:55,310,993...55,347,701
Ensembl chr 3:55,310,993...55,347,184

G

glutamate-rich 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERICH5 mRNA

NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207

G

glutamate-rich 6B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERICH6B mRNA

NCBI chr15:50,979,066...51,014,394

G

endoplasmic reticulum metallopeptidase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERMP1 mRNA

NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909

G

endoplasmic reticulum to nucleus signaling 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

endoplasmic reticulum protein 27

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ERP27 mRNA

PMID:25812627 PMID:32588087

NCBI chr 4:169,804,656...169,821,660
Ensembl chr 4:169,804,658...169,821,660

G

establishment of sister chromatid cohesion N-acetyltransferase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESCO2 mRNA

NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306

G

endothelial cell-specific molecule 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESM1 protein

NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804

G

extra spindle pole bodies like 1, separase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ESPL1 mRNA

NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984

G

estrogen receptor 1

multiple interactions

perfluoro-n-nonanoic acid binds to and results in increased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

electron transfer flavoprotein subunit beta lysine methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of ETFBKMT mRNA

NCBI chr 4:182,140,492...182,204,635
Ensembl chr 4:182,140,559...182,150,305

G

ETS variant transcription factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ETV1 mRNA

NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775

G

ETS variant transcription factor 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

exosome component 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXOSC5 mRNA

NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265

G

exosome component 8

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXOSC8 mRNA

NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928

G

exostosin-like glycosyltransferase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of EXTL1 mRNA

NCBI chr 5:146,573,911...146,589,115
Ensembl chr 5:146,573,912...146,589,115

G

EYA transcriptional coactivator and phosphatase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of EYA4 mRNA

NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976

G

coagulation factor X

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F10 mRNA

NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141

G

coagulation factor XI

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F11 mRNA

NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437

G

coagulation factor XIII B chain

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F13B mRNA

NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381

G

coagulation factor II (thrombin) receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

coagulation factor III, tissue factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F3 mRNA

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

coagulation factor IX

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of F9 mRNA

NCBI chr X:138,352,334...138,396,835
Ensembl chr X:138,352,298...138,396,835

G

fatty acid binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FABP1 mRNA

NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788

G

family with sequence similarity 168, member A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM168A mRNA

NCBI chr 1:155,057,352...155,203,439
Ensembl chr 1:155,057,352...155,201,220

G

family with sequence similarity 171, member A2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM171A2 mRNA

NCBI chr10:87,393,888...87,404,051
Ensembl chr10:87,394,007...87,404,053

G

family with sequence similarity 204, member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM204A mRNA

NCBI chr 1:259,328,551...259,366,726
Ensembl chr 1:259,337,709...259,367,077

G

FAM20A, golgi associated secretory pathway pseudokinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM20A mRNA

NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672

G

family with sequence similarity 222, member B

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM222B mRNA

NCBI chr10:62,986,571...63,052,350
Ensembl chr10:62,986,571...63,052,350

G

family with sequence similarity 241 member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM241A mRNA

NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242

G

family with sequence similarity 83, member D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAM83D mRNA

NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192

G

family with sequence similarity 89, member A

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM89A mRNA

NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631

G

family with sequence similarity 98, member C

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAM98C mRNA

NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385

G

FA complementation group A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FANCA mRNA

NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527

G

phenylalanyl-tRNA synthetase subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of FARSB mRNA

NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045

G

Fas cell surface death receptor

increases expression

perfluoro-n-nonanoic acid results in increased expression of FAS mRNA

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

fatty acid synthase

decreases expression
increases activity

perfluoro-n-nonanoic acid results in decreased expression of FASN mRNA
perfluoro-n-nonanoic acid results in increased activity of FASN protein

PMID:26056853 PMID:32588087

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

Fas-activated serine/threonine kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FASTK mRNA

NCBI chr 4:10,732,273...10,736,332
Ensembl chr 4:10,732,256...10,737,430

G

fatty acid hydroxylase domain containing 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FAXDC2 mRNA

NCBI chr10:42,245,808...42,271,679
Ensembl chr10:42,246,868...42,271,871

G

fibrillarin-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FBLL1 mRNA

NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299

G

fibrosin

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBRS mRNA

NCBI chr 1:182,090,741...182,104,026
Ensembl chr 1:182,089,844...182,103,828

G

F-box protein 32

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

F-box protein 39

increases expression

perfluoro-n-nonanoic acid results in increased expression of FBXO39 mRNA

NCBI chr10:56,929,699...56,934,911
Ensembl chr10:56,932,297...56,934,906

G

F-box protein 41

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXO41 mRNA

NCBI chr 4:118,007,517...118,039,547
Ensembl chr 4:118,010,978...118,039,406

G

F-box and WD repeat domain containing 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FBXW7 mRNA

NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941

G

farnesyl diphosphate farnesyl transferase 1

decreases expression
increases expression

perfluoro-n-nonanoic acid results in decreased expression of FDFT1 mRNA
perfluoro-n-nonanoic acid results in increased expression of FDFT1 mRNA

PMID:22071372 PMID:32588087

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

ferrochelatase

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of FECH mRNA

NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348

G

flap structure-specific endonuclease 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FEN1 mRNA

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

fetuin B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FETUB mRNA

NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135

G

fibroblast growth factor 21

increases expression

perfluoro-n-nonanoic acid results in increased expression of FGF21 mRNA

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor 23

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FGF23 protein

NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821

G

four and a half LIM domains 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of FHL2 mRNA

NCBI chr 9:45,388,979...45,462,421
Ensembl chr 9:45,388,981...45,431,192

G

filamin B

increases expression

perfluoro-n-nonanoic acid results in increased expression of FLNB mRNA

NCBI chr15:16,961,999...17,095,059
Ensembl chr15:16,962,003...17,095,006

G

Fms related receptor tyrosine kinase 3 ligand

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FLT3LG mRNA

NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463

G

FLYWCH-type zinc finger 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FLYWCH1 mRNA

NCBI chr10:12,774,644...12,794,373
Ensembl chr10:12,774,653...12,794,267

G

formin-like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of FMNL2 mRNA

NCBI chr 3:37,348,791...37,624,746
Ensembl chr 3:37,348,574...37,624,754

G

flavin containing dimethylaniline monoxygenase 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

flavin containing dimethylaniline monoxygenase 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO4 mRNA

NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874

G

flavin containing dimethylaniline monoxygenase 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

fibronectin 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FN1 mRNA

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

forkhead box A1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXA1 mRNA

NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188

G

forkhead box C1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FOXC1 mRNA

NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803

G

forkhead box M1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXO3 mRNA

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

forkhead box O4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FOXO4 mRNA

NCBI chr X:66,385,241...66,392,115
Ensembl chr X:66,385,558...66,392,115

G

FRAS1 related extracellular matrix 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FREM2 mRNA

NCBI chr 2:137,602,784...137,740,785
Ensembl chr 2:137,602,784...137,740,785

G

follicle stimulating hormone subunit beta

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of FSHB protein

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

follicle stimulating hormone receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FSHR mRNA

NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785

G

ferritin heavy chain 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

Fus RNA binding protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FUS mRNA

PMID:25812627 PMID:38568856

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

Friend virus susceptibility 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of C19ORF48P mRNA

NCBI chr 1:94,730,839...94,736,791
Ensembl chr 1:94,730,606...94,737,594

G

FYVE and coiled-coil domain autophagy adaptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FYCO1 mRNA

NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021

G

frizzled class receptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of FZD1 mRNA

NCBI chr 4:29,310,303...29,314,701
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643

G

glucose-6-phosphatase catalytic subunit 1

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of G6PC1 mRNA
perfluoro-n-nonanoic acid results in decreased expression of G6PC1 mRNA

PMID:22387981 PMID:32588087

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

glucose-6-phosphate dehydrogenase

increases activity

perfluoro-n-nonanoic acid results in increased activity of G6PD protein

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

GABA type A receptor associated protein like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GABARAPL2 mRNA

NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628

G

gamma-aminobutyric acid type A receptor subunit gamma 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GABRG2 mRNA

NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346

G

growth arrest and DNA-damage-inducible, alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of GADD45A mRNA

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, gamma

increases expression

perfluoro-n-nonanoic acid results in increased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase 11

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GALNT11 mRNA

NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140

G

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

increases expression

perfluoro-n-nonanoic acid results in increased expression of GART mRNA

NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125

G

growth arrest-specific 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GAS2 mRNA

NCBI chr 1:101,452,361...101,582,619
Ensembl chr 1:101,482,591...101,582,619

G

growth arrest-specific 2 like 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GAS2L3 mRNA

NCBI chr 7:23,803,578...23,836,816
Ensembl chr 7:23,806,310...23,836,411

G

growth arrest specific 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

GATA zinc finger domain containing 2A

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GATAD2A mRNA

NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587

G

glucosylceramidase beta 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBA3 mRNA

NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653

G

guanylate binding protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBP2 mRNA

NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571

G

guanylate binding protein 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GBP7 mRNA

NCBI chr 2:231,275,521...231,297,289
Ensembl chr 2:231,275,640...231,297,278

G

GRIP and coiled-coil domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GCC1 mRNA

NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663

G

glutaryl-CoA dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCDH mRNA

NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681

G

glucokinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCK mRNA

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

guanine deaminase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GDA mRNA

NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416

G

growth differentiation factor 15

increases expression

perfluoro-n-nonanoic acid results in increased expression of GDF15 mRNA

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

guided entry of tail-anchored proteins factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of WRB mRNA

NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973

G

glial fibrillary acidic protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GFAP mRNA

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

gamma-glutamyl hydrolase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GGH mRNA

NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787

G

GINS complex subunit 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GINS1 mRNA

NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936

G

gap junction protein, alpha 10

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GJA10 mRNA

NCBI chr 5:46,991,051...47,002,902
Ensembl chr 5:46,992,946...46,996,570

G

gap junction protein, beta 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GJB1 mRNA

NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925

G

gastrokine 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GKN2 mRNA

NCBI chr 4:119,778,326...119,824,366
Ensembl chr 4:119,818,280...119,824,363

G

galactosidase, beta 1-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of GLB1L mRNA

NCBI chr 9:76,693,325...76,705,548
Ensembl chr 9:76,695,173...76,705,510

G

glycine decarboxylase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

GLI family zinc finger 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLI1 mRNA

NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251

G

GLIS family zinc finger 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of GLIS3 mRNA

NCBI chr 1:225,976,029...226,395,849
Ensembl chr 1:225,976,326...226,395,899

G

glutaminase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLS2 mRNA

NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426

G

glutamate-ammonia ligase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

glycine-N-acyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLYAT mRNA

NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942

G

glycerate kinase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GLYCTK mRNA

NCBI chr 8:106,795,461...106,802,675
Ensembl chr 8:106,797,343...106,802,397

G

GNAS complex locus

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNAS mRNA

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

G

G protein subunit gamma transducin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNGT1 mRNA

NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252

G

G protein nucleolar 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of GNL3 mRNA

NCBI chr16:6,207,402...6,213,491
Ensembl chr16:6,207,402...6,213,392

G

glycine N-methyltransferase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GNMT mRNA

NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434

G

golgi phosphoprotein 3-like

increases expression

perfluoro-n-nonanoic acid results in increased expression of GOLPH3L mRNA

NCBI chr 2:183,151,941...183,183,094
Ensembl chr 2:183,153,301...183,183,083

G

glycerophosphocholine phosphodiesterase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPCPD1 mRNA

NCBI chr 3:119,787,681...119,832,550
Ensembl chr 3:119,787,682...119,832,517

G

glycerol-3-phosphate dehydrogenase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

G protein-coupled estrogen receptor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPER1 mRNA

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G

G protein-coupled receptor 22

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPR22 mRNA

NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486

G

G protein-coupled receptor 61

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPR61 mRNA

NCBI chr 2:195,781,931...195,789,798
Ensembl chr 2:195,782,752...195,789,621

G

G protein-coupled receptor 83

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPR83 mRNA

NCBI chr 8:11,693,540...11,704,028
Ensembl chr 8:11,693,540...11,704,028

G

G-protein coupled receptor 88

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPR88 mRNA

NCBI chr 2:204,191,443...204,199,576
Ensembl chr 2:204,191,427...204,199,733

G

G protein-coupled receptor, class C, group 5, member B

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPRC5B mRNA

NCBI chr 1:173,316,904...173,340,933
Ensembl chr 1:173,316,907...173,340,932

G

G protein-regulated inducer of neurite outgrowth 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPRIN1 mRNA

NCBI chr17:9,863,881...9,876,832
Ensembl chr17:9,863,571...9,876,915

G

glutamic--pyruvic transaminase

decreases expression
decreases activity
increases activity

perfluoro-n-nonanoic acid results in decreased expression of GPT mRNA
perfluoro-n-nonanoic acid results in decreased activity of GPT protein
perfluoro-n-nonanoic acid results in increased activity of GPT protein

PMID:26056853 PMID:29156323 PMID:32588087

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutamic--pyruvic transaminase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GPT2 mRNA

NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GPX8 mRNA

NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195

G

growth factor receptor bound protein 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GRB7 mRNA

NCBI chr10:83,443,387...83,453,057
Ensembl chr10:83,444,004...83,453,052

G

grainyhead-like transcription factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GRHL1 mRNA

NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301

G

glutaredoxin and cysteine rich domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GRXCR1 mRNA

NCBI chr14:40,004,169...40,126,571
Ensembl chr14:40,004,169...40,126,571

G

glycogen synthase kinase 3 beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSK3B protein modified form

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione S-transferase alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GSTA4 mRNA

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase mu 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSTM4 mRNA

NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323

G

glutathione S-transferase, mu 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of GSTM3 mRNA

PMID:28558994 PMID:35337807

NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553

G

glycosyltransferase-like domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTDC1 mRNA

NCBI chr 3:28,766,640...29,161,668
Ensembl chr 3:28,766,645...29,162,271

G

GTF2I repeat domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTF2IRD1 mRNA

NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040

G

GTP binding protein 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of GTPBP2 mRNA

NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241

G

G-2 and S-phase expressed 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GTSE1 mRNA

NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806

G

GTP binding elongation factor GUF1

increases expression

perfluoro-n-nonanoic acid results in increased expression of GUF1 mRNA

NCBI chr14:38,537,953...38,557,331
Ensembl chr14:38,537,953...38,557,331

G

glycogen synthase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of GYS2 mRNA

NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228

G

H1.0 linker histone

increases expression

perfluoro-n-nonanoic acid results in increased expression of H1-0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H1.4 linker histone, cluster member

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H1-4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

3-hydroxyanthranilate 3,4-dioxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAAO mRNA

NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877

G

hyaluronan binding protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HABP2 mRNA

NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of HADHA mRNA

PMID:22071372 PMID:23567314

NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of HADHB mRNA

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacyl glutathione hydrolase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAGH mRNA

NCBI chr10:13,874,883...13,889,527
Ensembl chr10:13,875,241...13,889,504

G

histidine ammonia lyase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAL mRNA

NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701

G

hydroxyacid oxidase 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HAO2 mRNA

NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425

G

hemoglobin subunit beta

multiple interactions

[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased expression of HBB-B1 mRNA

NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012

G

histone deacetylase 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HDAC7 mRNA

NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072

G

HDGF like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HDGFL2 mRNA

NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186

G

HEAT repeat containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HEATR1 mRNA

NCBI chr17:58,053,288...58,093,895
Ensembl chr17:58,051,700...58,093,948

G

heart development protein with EGF-like domains 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HEG1 mRNA

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

G

hexosaminidase D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HEXD mRNA

NCBI chr10:106,479,781...106,498,799
Ensembl chr10:106,480,194...106,498,799

G

homogentisate 1, 2-dioxygenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HGD mRNA

NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323

G

hepatocyte growth factor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HGF protein

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

hematopoietically expressed homeobox

increases expression

perfluoro-n-nonanoic acid results in increased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

hypoxia inducible factor 1 subunit alpha

affects methylation

perfluoro-n-nonanoic acid affects the methylation of HIF1A gene

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

histone cluster 1 H2a family member I like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H3C6 mRNA

NCBI chr17:41,568,181...41,569,093
Ensembl chr17:41,568,471...41,569,109

G

histone cluster 1, H2bc

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of H2BC21 mRNA

NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642

G

hemojuvelin BMP co-receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HJV mRNA

NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

hexokinase domain containing 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HKDC1 mRNA

NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867

G

high mobility group AT-hook 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGA1 mRNA

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

G

high mobility group AT-hook 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGA2 mRNA

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

G

3-hydroxy-3-methylglutaryl-CoA reductase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGCR mRNA

PMID:21641976 PMID:32588087

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

increases expression
decreases expression

perfluoro-n-nonanoic acid results in increased expression of HMGCS2 mRNA
perfluoro-n-nonanoic acid results in decreased expression of HMGCS2 mRNA

PMID:23567314 PMID:32588087

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

hyaluronan-mediated motility receptor

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HMMR mRNA

NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060

G

heme oxygenase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, alpha

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNF4A mRNA

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

G

histamine N-methyltransferase

increases expression

perfluoro-n-nonanoic acid results in increased expression of HNMT mRNA

NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012

G

heterogeneous nuclear ribonucleoprotein A0

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNRNPA0 mRNA

NCBI chr17:6,507,728...6,510,385
Ensembl chr17:6,507,275...6,509,375

G

heterogeneous nuclear ribonucleoprotein U-like 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HNRNPUL2 mRNA

NCBI chr 1:205,713,431...205,725,553
Ensembl chr 1:205,711,886...205,725,553

G

homeo box A5

multiple interactions
increases expression

PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXA5 mRNA]

NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234

G

homeo box B7

decreases expression
increases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of HOXB7 protein
perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA
NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXB7 mRNA]

NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034

G

homeo box B9

increases expression

perfluoro-n-nonanoic acid results in increased expression of HOXB9 mRNA

NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818

G

homeo box C5

increases expression
multiple interactions
affects expression

perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA
NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXC5 mRNA]
perfluoro-n-nonanoic acid affects the expression of HOXC5 protein

NCBI chr 7:134,150,988...134,154,410
Ensembl chr 7:134,150,988...134,154,410

G

homeo box D10

multiple interactions
increases expression

NFE2L2 protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]; PPARA protein affects the reaction [perfluoro-n-nonanoic acid results in increased expression of HOXD10 mRNA]

NCBI chr 3:59,594,516...59,597,725
Ensembl chr 3:59,594,516...59,597,725

G

homeobox D8

increases expression

perfluoro-n-nonanoic acid results in increased expression of HOXD8 mRNA

NCBI chr 3:59,607,793...59,610,359
Ensembl chr 3:59,607,996...59,610,361

G

15-hydroxyprostaglandin dehydrogenase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HPGD mRNA

NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228

G

HRas proto-oncogene, GTPase

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRAS mRNA

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

histidine rich carboxyl terminus 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRCT1 mRNA

NCBI chr 5:57,982,344...57,983,186
Ensembl chr 5:57,982,470...57,982,790

G

histidine-rich glycoprotein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HRG mRNA

NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389

G

hydroxysteroid 11-beta dehydrogenase 1

multiple interactions

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA

NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687

G

hydroxysteroid 11-beta dehydrogenase 2

decreases activity

perfluoro-n-nonanoic acid results in decreased activity of HSD11B2 protein

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 13

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSD17B13 mRNA

NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions
decreases expression

[perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD17B3 mRNA
perfluoro-n-nonanoic acid results in decreased expression of HSD17B3 mRNA; perfluoro-n-nonanoic acid results in decreased expression of HSD17B3 protein

PMID:25588985 PMID:30294798

NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554

G

hydroxysteroid (17-beta) dehydrogenase 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSD17B6 mRNA

NCBI chr 7:422,466...442,008
Ensembl chr 7:422,480...442,425

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

decreases expression
decreases activity

perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 mRNA
perfluoro-n-nonanoic acid results in decreased activity of HSD3B1 protein
perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 mRNA; perfluoro-n-nonanoic acid results in decreased expression of HSD3B1 protein

PMID:30294798 PMID:32588087 PMID:36122607

NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999

G

hydroxysteroid dehydrogenase like 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSDL2 mRNA

NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839

G

heat shock protein family A (Hsp70) member 13

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

HSPB1 associated protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of HSPBAP1 mRNA

NCBI chr11:64,940,089...64,994,753
Ensembl chr11:64,940,091...64,994,756

G

heparan sulfate proteoglycan 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of HSPG2 mRNA

NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594

G

isoleucyl-tRNA synthetase 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IARS1 mRNA

NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237

G

intercellular adhesion molecule 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

isocitrate dehydrogenase (NADP(+)) 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDH2 mRNA

NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDH3B mRNA

NCBI chr 3:117,481,845...117,486,909
Ensembl chr 3:117,481,845...117,486,982

G

isopentenyl-diphosphate delta isomerase 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

immediate early response 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IER3 mRNA

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

immediate early response 5

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IER5 mRNA

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

interferon induced transmembrane protein 2

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IFITM2 mRNA

NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741

G

interferon gamma

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of IFNG protein
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in decreased abundance of IFNG protein

PMID:19878704 PMID:36270329

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon, lambda 3

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IFNL3 mRNA

NCBI chr 1:83,814,456...83,816,096
Ensembl chr 1:83,814,564...83,816,096

G

interferon-related developmental regulator 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFRD1 mRNA

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

interferon-related developmental regulator 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFRD2 mRNA

NCBI chr 8:108,260,969...108,266,191
Ensembl chr 8:108,260,969...108,266,194

G

intraflagellar transport 20

increases expression

perfluoro-n-nonanoic acid results in increased expression of IFT20 mRNA

NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124

G

insulin-like growth factor 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IGFBP1 mRNA

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of IGFBP3 mRNA

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

interleukin 10

decreases expression
multiple interactions

perfluoro-n-nonanoic acid results in decreased expression of IL10 protein
gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of IL10 protein]

PMID:19878704 PMID:22648072

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 15 receptor subunit alpha

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL15RA mRNA

NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278

G

interleukin 17 receptor B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL17RB mRNA

NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125

G

interleukin 18

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 18 receptor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL18R1 mRNA

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

G

interleukin 1 beta

multiple interactions
increases secretion
increases expression

gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of IL1B protein]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]; IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT2 mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]]; prolinedithiocarbamate inhibits the reaction [IL1B protein inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]]
perfluoro-n-nonanoic acid results in increased secretion of IL1B protein

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 1 receptor-like 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL1RL1 mRNA

NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256

G

interleukin 2

decreases secretion

perfluoro-n-nonanoic acid results in decreased secretion of IL2 protein

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 20 receptor subunit beta

increases expression

perfluoro-n-nonanoic acid results in increased expression of IL20RB mRNA

NCBI chr 8:100,979,085...101,010,829
Ensembl chr 8:100,980,383...101,009,942

G

interleukin 22 receptor subunit alpha 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL22RA1 mRNA

NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296

G

interleukin 27

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IL27 mRNA

NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582

G

interleukin 4

increases secretion

perfluoro-n-nonanoic acid results in increased secretion of IL4 protein

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

increases expression
affects expression
multiple interactions

perfluoro-n-nonanoic acid results in increased expression of IL6 protein
perfluoro-n-nonanoic acid affects the expression of IL6 protein
[perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with perfluoro-n-nonanoic acid co-treated with perfluorohexanesulfonic acid co-treated with ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate] results in increased abundance of IL6 protein

PMID:19878704 PMID:22648072 PMID:36270329

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

inner centromere protein

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INCENP mRNA

NCBI chr 1:206,520,655...206,550,575
Ensembl chr 1:206,523,380...206,553,265

G

inhibin subunit beta B

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INHBB mRNA; perfluoro-n-nonanoic acid results in decreased expression of INHBB protein

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

G

inhibin subunit beta C

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INHBC mRNA

NCBI chr 7:63,184,141...63,197,630
Ensembl chr 7:63,184,142...63,197,630

G

inhibin subunit beta E

increases expression

perfluoro-n-nonanoic acid results in increased expression of INHBE mRNA

NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172

G

INO80 complex subunit E

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INO80E mRNA

NCBI chr 1:181,461,406...181,472,059
Ensembl chr 1:181,461,408...181,472,469

G

inositol polyphosphate-5-phosphatase B

increases expression

perfluoro-n-nonanoic acid results in increased expression of INPP5B mRNA

NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315

G

inositol polyphosphate phosphatase-like 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INPPL1 mRNA

NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500

G

insulin induced gene 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

integrator complex subunit 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of INTS7 mRNA

NCBI chr13:103,155,123...103,207,953
Ensembl chr13:103,155,090...103,208,592

G

importin 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of IPO4 mRNA

NCBI chr15:29,117,365...29,127,382
Ensembl chr15:29,117,365...29,127,285

G

IQ motif containing B1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IQCB1 mRNA

NCBI chr11:63,905,595...63,960,141
Ensembl chr11:63,905,590...63,960,093

G

interleukin-1 receptor-associated kinase 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRAK2 mRNA

NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602

G

interferon regulatory factor 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRF1 mRNA

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 2 binding protein 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRF2BP1 mRNA

NCBI chr 1:78,652,736...78,655,437
Ensembl chr 1:78,652,412...78,655,530

G

interferon regulatory factor 6

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRF6 mRNA

NCBI chr13:104,672,179...104,691,386
Ensembl chr13:104,672,179...104,691,386

G

interferon regulatory factor 7

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

insulin receptor substrate 1

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRS1 protein modified form

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

insulin receptor substrate 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of IRS2 mRNA

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

iroquois homeobox 4

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of IRX4 mRNA

NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549

G

integrin subunit alpha 2

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITGA2 mRNA

PMID:25812627 PMID:32588087

NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 5

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITGA5 mRNA

NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837

G

integrin subunit alpha D

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGAD mRNA

NCBI chr 1:182,759,762...182,788,422
Ensembl chr 1:182,759,740...182,788,161

G

integrin subunit alpha L

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGAL mRNA

NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732

G

integrin subunit beta 7

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGB7 mRNA

NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876

G

integrin subunit beta 8

decreases expression

perfluoro-n-nonanoic acid results in decreased expression of ITGB8 mRNA

NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476

G

inositol-trisphosphate 3-kinase A

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITPKA mRNA

NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600

G

inositol 1,4,5-trisphosphate receptor, type 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of ITPR1 mRNA

NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491

G

jagged canonical Notch ligand 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of JAG1 mRNA

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

jumonji domain containing 4

increases expression

perfluoro-n-nonanoic acid results in increased expression of JMJD4 mRNA

NCBI chr10:44,234,465...44,242,754
Ensembl chr10:44,234,549...44,240,065

G

junction mediating and regulatory protein, p53 cofactor

increases expression

perfluoro-n-nonanoic acid results in increased expression of JMY mRNA

NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006

G

junctophilin 1

increases expression

perfluoro-n-nonanoic acid results in increased expression of JPH1 mRNA

NCBI chr 5:2,030,227...2,137,171
Ensembl chr 5:2,030,281...2,125,284

G

JPX transcript, XIST activator

increases expression

perfluoro-n-nonanoic acid results in increased expression of JPX mRNA

NCBI chr X:68,511,491...68,665,132

G

JunB proto-oncogene, AP-1 transcription factor subunit

increases expression

perfluoro-n-nonanoic acid results in increased expression of JUNB mRNA

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

KAT8 regulatory NSL complex subunit 3

increases expression

perfluoro-n-nonanoic acid results in increased expression of KANSL3 mRNA

NCBI chr 9:38,562,170...38,605,757
Ensembl chr 9:38,562,177...38,605,692