CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: mesotrione
Accession: CHEBI:38321
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Definition: An aromatic ketone that is cyclohexa-1,3-dione in which one of the hydrogens at position 2 is substituted by a 4-(methanesulfonyl)-2-nitrobenzoyl group.
Synonyms: exact_synonym: 2-[4-(methanesulfonyl)-2-nitrobenzoyl]cyclohexane-1,3-dione
related_synonym: (2-nitro-4-(methylsullfonyl))benzoylcyclohexane-1,3-dione; 2-(2'-nitro-4'-methylsulfonylbenzoyl)cyclohexane-1,3-dione; 2-(4-methylsulphonyl-2-nitrobenzoyl)-1,3-cyclohexanedione; 2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione; Formula=C14H13NO7S; InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3; InChIKey=KPUREKXXPHOJQT-UHFFFAOYSA-N; SMILES=CS(=O)(=O)c1ccc(C(=O)C2C(=O)CCCC2=O)c(c1)[N+]([O-])=O; Tenacity
xref: CAS:104206-82-8
xref_mesh: MESH:C432907
xref: PMID:11455642; PMID:20692682; PPDB:442; Patent:WO2011016018; Pesticides:mesotrione; Reaxys:8999656; Wikipedia:Mesotrione
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Lrrc4c
leucine rich repeat containing 4C
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of LRRC4C gene
CTD
PMID:34516295
NCBI chr 3:82,305,495...83,684,039
Ensembl chr 3:83,483,851...83,687,774
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Mfsd4b2
major facilitator superfamily domain containing 4B2
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MFSD4B gene
CTD
PMID:34516295
NCBI chr20:43,344,601...43,353,061
Ensembl chr20:43,344,601...43,353,061
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Ms4a4a
membrane spanning 4-domains A4A
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MS4A4A gene
CTD
PMID:34516295
NCBI chr 1:208,060,507...208,085,121
Ensembl chr 1:208,046,971...208,085,119
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Myo1b
myosin Ib
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of MYO1B gene
CTD
PMID:34516295
NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798
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Pik3r4
phosphoinositide-3-kinase, regulatory subunit 4
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of PIK3R4 gene
CTD
PMID:34516295
NCBI chr 8:106,267,908...106,316,585
Ensembl chr 8:106,267,954...106,316,584
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Ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of PPP1R2 gene
CTD
PMID:34516295
NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463
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Schip1
schwannomin interacting protein 1
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of SCHIP1 gene
CTD
PMID:34516295
NCBI chr 2:152,127,171...152,888,587
Ensembl chr 2:152,126,953...152,888,585
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Wdr43
WD repeat domain 43
multiple interactions
ISO
[Herbicides results in increased abundance of mesotrione] which affects the methylation of WDR43 gene
CTD
PMID:34516295
NCBI chr 6:23,845,499...23,884,846
Ensembl chr 6:23,845,499...23,884,846
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Gclc
glutamate-cysteine ligase, catalytic subunit
multiple interactions
ISO
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA
CTD
PMID:12899938
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions
ISO
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA
CTD
PMID:12899938
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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Hmox1
heme oxygenase 1
multiple interactions
ISO
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA
CTD
PMID:12899938
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hpd
4-hydroxyphenylpyruvate dioxygenase
multiple interactions
ISO
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLC mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of GCLM mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of HMOX1 mRNA; [nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA
CTD
PMID:12899938
NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions
ISO
[nitisinone results in decreased activity of HPD protein] which results in decreased expression of NQO1 mRNA
CTD
PMID:12899938
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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