The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA mRNA]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA protein]
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CRH mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CRHR1 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of CYP11A1 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of ESR2 mRNA
3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 protein]
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of FKBP5 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of GRIN2B mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of HTR1A mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of HTR2A mRNA
3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA mRNA]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of CEBPA protein]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 protein]; 3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; [3,5,6-trichloro-2-pyridinol co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG protein
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of MC2R mRNA
3,5,6-trichloro-2-pyridinol results in decreased expression of NES mRNA 3,5,6-trichloro-2-pyridinol results in increased expression of NES mRNA 3,5,6-trichloro-2-pyridinol affects the expression of NES mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] affects the expression of NR3C1 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of NR3C2 mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXT mRNA
[diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate co-treated with bis(2-propylheptyl)phthalate co-treated with bisphenol A co-treated with 3,5,6-trichloro-2-pyridinol co-treated with 3-phenoxybenzoic acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of OXTR mRNA
3,5,6-trichloro-2-pyridinol results in decreased activity of PNPLA6 protein 3,5,6-trichloro-2-pyridinol results in increased expression of PNPLA6 mRNA 3,5,6-trichloro-2-pyridinol results in decreased expression of PNPLA6 mRNA
3,5,6-trichloro-2-pyridinol promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]; [3,5,6-trichloro-2-pyridinol co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG protein
FLT4 protein inhibits the reaction [ciclopirox results in decreased phosphorylation of MAPK1 protein]; FLT4 protein inhibits the reaction [ciclopirox results in decreased phosphorylation of MAPK3 protein] ciclopirox results in increased degradation of FLT4 protein [ciclopirox results in decreased expression of FLT4 protein] which results in decreased phosphorylation of MAPK1 protein; [ciclopirox results in decreased expression of FLT4 protein] which results in decreased phosphorylation of MAPK3 protein
ciclopirox results in increased expression of and results in increased localization of HIF1A protein ciclopirox results in increased stability of HIF1A protein
ciclopirox inhibits the reaction [Terfenadine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]]; ciclopirox promotes the reaction [KCNH2 protein results in increased transport of Thallium]
ciclopirox results in decreased phosphorylation of MAPK1 protein FLT4 protein inhibits the reaction [ciclopirox results in decreased phosphorylation of MAPK1 protein] [ciclopirox results in decreased expression of FLT4 protein] which results in decreased phosphorylation of MAPK1 protein; ciclopirox promotes the reaction [U 0126 results in decreased phosphorylation of MAPK1 protein]
FLT4 protein inhibits the reaction [ciclopirox results in decreased phosphorylation of MAPK3 protein] [Ciclopirox results in decreased expression of FLT4 protein] which results in decreased phosphorylation of MAPK3 protein; Ciclopirox promotes the reaction [U 0126 results in decreased phosphorylation of MAPK3 protein]
deferiprone inhibits the reaction [ferrous sulfate results in increased phosphorylation of AKT1 protein]; deferiprone inhibits the reaction [Iron results in increased phosphorylation of AKT1 protein]
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in decreased expression of BCL2 protein]
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of CACNA1C protein]
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of and results in increased cleavage of CASP3 protein]
deferiprone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] deferiprone inhibits the reaction [[Lipopolysaccharides co-treated with Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein]
deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]]; deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of CHUK protein]
Deferiprone inhibits the reaction [erastin results in increased expression of FTH1 protein] Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of FTH1 protein]
deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]]; deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]]
Deferiprone inhibits the reaction [ferrous sulfate results in increased phosphorylation of MAPK1 protein]; Deferiprone inhibits the reaction [Iron results in increased phosphorylation of MAPK1 protein] Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK1 protein]
deferiprone inhibits the reaction [ferrous sulfate results in increased phosphorylation of MAPK3 protein]; deferiprone inhibits the reaction [Iron results in increased phosphorylation of MAPK3 protein] Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of MAPK3 protein]
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased phosphorylation of NFKBIA protein]
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of SLC11A2 protein]
deferiprone results in increased expression of TF mRNA; deferiprone results in increased expression of TF protein deferiprone results in decreased uptake of TF protein
Deferiprone inhibits the reaction [[Iron-Dextran Complex results in increased abundance of Iron] which results in increased expression of TFRC protein]
ABCB1A gene mutant form affects the transport of and results in increased abundance of huperzine A ABCB1 protein results in increased transport of huperzine A Elacridar inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of huperzine A]
huperzine A results in decreased activity of ACHE protein huperzine A binds to and results in decreased activity of ACHE protein ALB protein affects the reaction [huperzine A results in decreased activity of ACHE protein]; huperzine A inhibits the reaction [ACHE protein results in increased hydrolysis of Butyrylthiocholine] [huperzine A co-treated with tetramethylpyrazine] results in decreased activity of ACHE protein
Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; ferrous sulfate inhibits the reaction [Mimosine results in decreased activity of TNF protein] Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; CAT protein inhibits the reaction [Mimosine results in decreased activity of TNF protein]
ACMSD protein affects the abundance of N'-methyl-2-pyridone-5-carboxamide [ACMSD protein affects the metabolism of Niacin] which affects the abundance of N'-methyl-2-pyridone-5-carboxamide
pirfenidone results in decreased expression of ACTA2 mRNA; pirfenidone results in decreased expression of ACTA2 protein pirfenidone inhibits the reaction [Adenine results in increased expression of ACTA2 mRNA] pirfenidone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]
pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MYD88 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of TLR4 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA protein]; pirfenidone inhibits the reaction [AGT protein results in increased phosphorylation of RELA protein] pirfenidone inhibits the reaction [AGT protein results in increased expression of IL1B mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of IL1B protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of IL6 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of TNF mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of TNF protein]; pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA protein]
pirfenidone inhibits the reaction [Paraquat results in increased activity of CAT protein] [Prednisolone co-treated with pirfenidone] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; pirfenidone inhibits the reaction [Paraquat results in decreased activity of CAT protein]
pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] pirfenidone inhibits the reaction [Adenine results in decreased expression of CDH1 protein]
pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA] pirfenidone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA] pirfenidone results in decreased expression of COL1A1 mRNA
[pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein; [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in increased phosphorylation of EGFR protein; lapatinib promotes the reaction [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]]; lapatinib promotes the reaction [pirfenidone inhibits the reaction [EGFR protein binds to PTPN3 protein]]; pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]; pirfenidone inhibits the reaction [EGFR protein binds to PTPN3 protein]; pirfenidone promotes the reaction [lapatinib inhibits the reaction [EGFR protein binds to MAPK12 protein]]; pirfenidone promotes the reaction [lapatinib inhibits the reaction [EGFR protein binds to PTPN3 protein]]
[pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein]] which results in decreased susceptibility to Tamoxifen; pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein]
pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein] pirfenidone inhibits the reaction [Adenine results in increased expression of FN1 protein]
pirfenidone inhibits the reaction [AGT protein results in increased expression of IL1B mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of IL1B protein]
pirfenidone inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of IL6 protein]
[pirfenidone inhibits the reaction [MAPK12 protein results in increased expression of JUN protein]] which results in decreased susceptibility to Tamoxifen; pirfenidone inhibits the reaction [MAPK12 protein results in increased expression of JUN protein]
pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR protein] pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of KDR protein]
[pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein; [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in increased phosphorylation of EGFR protein; [pirfenidone inhibits the reaction [MAPK12 protein results in increased expression of JUN protein]] which results in decreased susceptibility to Tamoxifen; [pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein]] which results in decreased susceptibility to Tamoxifen; lapatinib promotes the reaction [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]]; pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]; pirfenidone inhibits the reaction [MAPK12 protein results in increased expression of JUN protein]; pirfenidone inhibits the reaction [MAPK12 protein results in increased phosphorylation of ESR1 protein]; pirfenidone promotes the reaction [lapatinib inhibits the reaction [EGFR protein binds to MAPK12 protein]]
pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of MMP2 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of MMP2 mRNA]; pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of MMP2 mRNA]] pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP2 protein]
pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of MMP9 protein]
[pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein; lapatinib promotes the reaction [pirfenidone inhibits the reaction [EGFR protein binds to PTPN3 protein]]; pirfenidone inhibits the reaction [EGFR protein binds to PTPN3 protein]; pirfenidone promotes the reaction [lapatinib inhibits the reaction [EGFR protein binds to PTPN3 protein]]
pirfenidone inhibits the reaction [Adenine results in increased expression of RELA mRNA] pirfenidone inhibits the reaction [AGT protein results in increased phosphorylation of RELA protein]
pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 mRNA] pirfenidone inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 mRNA]
pirfenidone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of TGFB1 protein] pirfenidone inhibits the reaction [Busulfan results in increased expression of TGFB1 mRNA] pirfenidone inhibits the reaction [Adenine results in increased expression of TGFB1 mRNA]; pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]]
pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]; pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]]; pirfenidone promotes the reaction [Tacrolimus results in decreased expression of TIMP1 mRNA]
[pirfenidone co-treated with Prednisolone] inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; pirfenidone inhibits the reaction [Adenine results in increased expression of TNF mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of TNF mRNA] pirfenidone inhibits the reaction [AGT protein results in increased expression of TNF mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of TNF protein]
pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA protein] pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA mRNA]; pirfenidone inhibits the reaction [AGT protein results in increased expression of VEGFA protein]
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