|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
EXP |
1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde |
CTD |
PMID:21842885 |
|
NCBI chr 1:205,269,967...205,280,365
|
|
G |
Fgf1 |
fibroblast growth factor 1 |
decreases secretion |
ISO |
FGF1 protein results in decreased secretion of malealdehyde |
CTD |
PMID:16222742 |
|
NCBI chr18:30,937,670...31,023,786
|
|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
malealdehyde results in increased expression of GCLC mRNA |
CTD |
PMID:35750087 |
|
NCBI chr 8:87,510,251...87,548,896
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
affects expression |
ISO |
malealdehyde affects the expression of GSTP1 mRNA |
CTD |
PMID:35750087 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Hdac2 |
histone deacetylase 2 |
affects expression |
ISO |
malealdehyde affects the expression of HDAC2 mRNA |
CTD |
PMID:35750087 |
|
NCBI chr20:42,101,815...42,126,486
|
|
G |
Hdac8 |
histone deacetylase 8 |
increases expression |
ISO |
malealdehyde results in increased expression of HDAC8 mRNA |
CTD |
PMID:35750087 |
|
NCBI chr X:67,385,288...67,593,014
|
|
G |
Hdac9 |
histone deacetylase 9 |
affects expression |
ISO |
malealdehyde affects the expression of HDAC9 mRNA |
CTD |
PMID:35750087 |
|
NCBI chr 6:56,489,472...57,351,654
|
|
G |
Tp53 |
tumor protein p53 |
decreases expression |
ISO |
malealdehyde results in decreased expression of TP53 mRNA |
CTD |
PMID:35750087 |
|
NCBI chr10:54,798,871...54,810,300
|
|
G |
Txn1 |
thioredoxin 1 |
decreases activity |
ISO |
malealdehyde results in decreased activity of TXN1 protein |
CTD |
PMID:27402187 |
|
NCBI chr 5:77,507,455...77,519,685
|
|