Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:but-2-enedial
go back to main search page
Accession:CHEBI:38123 term browser browse the term
Definition:A dialdehyde that has formula C4H4O2.
Synonyms:related_synonym: Formula=C4H4O2;   InChI=1S/C4H4O2/c5-3-1-2-4-6/h1-4H;   InChIKey=JGEMYUOFGVHXKV-UHFFFAOYSA-N;   SMILES=[H]C(=O)C([H])=C([H])C([H])=O
 xref: Beilstein:8391537



show annotations for term's descendants           Sort by:
fumaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde CTD PMID:21842885 NCBI chr 1:205,269,967...205,280,365 JBrowse link
G Fgf1 fibroblast growth factor 1 decreases secretion ISO FGF1 protein results in decreased secretion of malealdehyde CTD PMID:16222742 NCBI chr18:30,937,670...31,023,786 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO malealdehyde results in increased expression of GCLC mRNA CTD PMID:35750087 NCBI chr 8:87,510,251...87,548,896 JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression ISO malealdehyde affects the expression of GSTP1 mRNA CTD PMID:35750087 NCBI chr 1:210,767,237...210,770,242 JBrowse link
G Hdac2 histone deacetylase 2 affects expression ISO malealdehyde affects the expression of HDAC2 mRNA CTD PMID:35750087 NCBI chr20:42,101,815...42,126,486 JBrowse link
G Hdac8 histone deacetylase 8 increases expression ISO malealdehyde results in increased expression of HDAC8 mRNA CTD PMID:35750087 NCBI chr  X:67,385,288...67,593,014 JBrowse link
G Hdac9 histone deacetylase 9 affects expression ISO malealdehyde affects the expression of HDAC9 mRNA CTD PMID:35750087 NCBI chr 6:56,489,472...57,351,654 JBrowse link
G Tp53 tumor protein p53 decreases expression ISO malealdehyde results in decreased expression of TP53 mRNA CTD PMID:35750087 NCBI chr10:54,798,871...54,810,300 JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO malealdehyde results in decreased activity of TXN1 protein CTD PMID:27402187 NCBI chr 5:77,507,455...77,519,685 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    role 19869
      application 19715
        solvent 17264
          formic acid 9425
            formyl group 9386
              aldehyde 9386
                dialdehyde 141
                  but-2-enedial 9
                    fumaraldehyde 9
                    malealdehyde 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            heteroorganic entity 19535
                              organochalcogen compound 19296
                                organooxygen compound 19213
                                  carbon oxoacid 18682
                                    carboxylic acid 18679
                                      carboacyl group 17726
                                        univalent carboacyl group 17726
                                          formyl group 9386
                                            aldehyde 9386
                                              dialdehyde 141
                                                but-2-enedial 9
                                                  fumaraldehyde 9
                                                  malealdehyde 0
paths to the root