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G |
Crp |
C-reactive protein |
decreases expression |
ISO |
Colesevelam Hydrochloride results in decreased expression of CRP protein |
CTD |
PMID:16616026 |
|
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions increases expression |
ISO |
Colesevelam Hydrochloride promotes the reaction [Simvastatin results in increased expression of HMGCR mRNA] Colesevelam Hydrochloride results in increased expression of HMGCR mRNA |
CTD |
PMID:22120639 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
Colesevelam Hydrochloride results in increased expression of LDLR mRNA |
CTD |
PMID:22120639 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Dek |
DEK proto-oncogene |
decreases secretion |
ISO |
DEK protein results in decreased secretion of Polyglutamic Acid |
CTD |
PMID:28558019 |
|
NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
affects localization |
EXP |
Polyglutamic Acid affects the localization of HSPA8 protein |
CTD |
PMID:10469394 |
|
NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases activity |
ISO |
Polyynes results in decreased activity of ABCB1 protein |
CTD |
PMID:18425719 |
|
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
decreases expression |
ISO |
Polyethylene results in decreased expression of ACP5 mRNA |
CTD |
PMID:15585240 |
|
NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Ascl1 |
achaete-scute family bHLH transcription factor 1 |
decreases expression |
ISO |
Polyethylene results in decreased expression of ASCL1 mRNA |
CTD |
PMID:23203475 |
|
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
Polyethylene results in decreased expression of BGLAP protein |
CTD |
PMID:10225790 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Cat |
catalase |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of CAT protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein |
CTD |
PMID:38180308 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Col1a1 |
collagen type I alpha 1 chain |
decreases expression |
ISO |
Polyethylene results in decreased expression of COL1A1 mRNA |
CTD |
PMID:11216681 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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|
G |
Csf2 |
colony stimulating factor 2 |
affects secretion |
ISO |
Polyethylene affects the secretion of CSF2 protein |
CTD |
PMID:15046894 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
decreases expression |
ISO |
Polyethylene results in decreased expression of FOS mRNA |
CTD |
PMID:15585240 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxg1 |
forkhead box G1 |
decreases expression |
ISO |
Polyethylene results in decreased expression of FOXG1 mRNA |
CTD |
PMID:23203475 |
|
NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of GPT protein |
CTD |
PMID:38180308 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Hes5 |
hes family bHLH transcription factor 5 |
decreases expression |
ISO |
Polyethylene results in decreased expression of HES5 mRNA |
CTD |
PMID:23203475 |
|
NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 protein] |
CTD |
PMID:38180308 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
Polyethylene analog promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:10602080 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
Polyethylene results in increased expression of IL6 mRNA; Polyethylene results in increased expression of IL6 protein [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of IL6 protein; Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:10602080 PMID:11771709 PMID:38180308 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] |
CTD |
PMID:38180308 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Litaf |
lipopolysaccharide-induced TNF factor |
increases expression |
ISO |
Polyethylene results in increased expression of LITAF mRNA |
CTD |
PMID:17408380 |
|
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
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G |
Neurod1 |
neuronal differentiation 1 |
decreases expression |
ISO |
Polyethylene results in decreased expression of NEUROD1 mRNA |
CTD |
PMID:23203475 |
|
NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of NFE2L2 protein; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of NFE2L2 mRNA; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:38180308 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Notch1 |
notch receptor 1 |
decreases expression |
ISO |
Polyethylene results in decreased expression of NOTCH1 mRNA |
CTD |
PMID:23203475 |
|
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased phosphorylation of RELA protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased phosphorylation of RELA protein] |
CTD |
PMID:38180308 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
increases expression |
ISO |
Polyethylene results in increased expression of SRC mRNA |
CTD |
PMID:15585240 |
|
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
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|
G |
Tnf |
tumor necrosis factor |
increases expression multiple interactions affects secretion |
ISO |
Polyethylene results in increased expression of TNF mRNA [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of TNF protein; Polyethylene analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Polyethylene affects the secretion of TNF protein Etidronic Acid inhibits the reaction [Polyethylene affects the secretion of TNF protein]; ibandronic acid inhibits the reaction [Polyethylene affects the secretion of TNF protein] |
CTD |
PMID:10413987 PMID:10602080 PMID:17408380 PMID:38180308 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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|
G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
decreases expression decreases secretion |
ISO |
Polyethylene results in decreased expression of TNFRSF11B protein Polyethylene results in decreased secretion of TNFRSF11B protein |
CTD |
PMID:15046894 PMID:15585240 |
|
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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|
G |
Tnfsf11 |
TNF superfamily member 11 |
affects secretion increases secretion |
ISO |
Polyethylene affects the secretion of TNFSF11 protein Polyethylene results in increased secretion of TNFSF11 protein |
CTD |
PMID:15046894 PMID:15585240 |
|
NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Alox5 |
arachidonate 5-lipoxygenase |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of ALOX5 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of ANXA2 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Ccna1 |
cyclin A1 |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of CCNA1 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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G |
Cd14 |
CD14 molecule |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of CD14 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd27 |
CD27 molecule |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of CD27 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of CDK1 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk4 |
cyclin-dependent kinase 4 |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of CDK4 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Dbf4 |
DBF4-CDC7 kinase regulatory subunit |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of DBF4 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:25,676,570...25,701,152
Ensembl chr 4:25,676,634...25,701,066
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G |
Dusp1 |
dual specificity phosphatase 1 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of DUSP1 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr10:16,680,478...16,683,275
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G |
Gmps |
guanine monophosphate synthase |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of GMPS mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 2:148,441,369...148,491,908
Ensembl chr 2:148,435,643...148,485,875
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of HSP90B1 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of HSPD1 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Ik |
IK cytokine |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of IK mRNA |
CTD |
PMID:16308212 |
|
NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832
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G |
Il9r |
interleukin 9 receptor |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of IL9R mRNA |
CTD |
PMID:16308212 |
|
NCBI chr10:15,431,706...15,444,144
Ensembl chr10:15,431,706...15,441,990
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
affects expression |
ISO |
poly(propyleneimine) analog affects the expression of MET mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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G |
Pccb |
propionyl-CoA carboxylase subunit beta |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of PCCB mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of PCNA mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Psma4 |
proteasome 20S subunit alpha 4 |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of PSMA4 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
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G |
Psmb4 |
proteasome 20S subunit beta 4 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of PSMB4 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746
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G |
Rpa3 |
replication protein A3 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of RPA3 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709
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G |
Rpl8 |
ribosomal protein L8 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of RPL8 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482 Ensembl chr 3:108,622,324...108,628,482
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G |
Rxra |
retinoid X receptor alpha |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of RXRA mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Smarca4 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of SMARCA4 mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975
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G |
Tgfa |
transforming growth factor alpha |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of TGFA mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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G |
Tpr |
translocated promoter region, nuclear basket protein |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of TPR mRNA |
CTD |
PMID:16308212 |
|
NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
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G |
Tubb4a |
tubulin, beta 4A class IVa |
increases expression |
ISO |
poly(propyleneimine) analog results in increased expression of TUBB4A mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 9:1,917,841...1,925,286
Ensembl chr 9:1,917,845...1,925,291
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G |
Ywhaq |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta |
decreases expression |
ISO |
poly(propyleneimine) analog results in decreased expression of YWHAQ mRNA |
CTD |
PMID:16308212 |
|
NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
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|
G |
C3 |
complement C3 |
increases expression |
ISO |
styrofoam analog results in increased expression of C3 protein |
CTD |
PMID:19428933 |
|
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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G |
C5 |
complement C5 |
increases expression |
ISO |
styrofoam analog results in increased expression of C5 protein |
CTD |
PMID:19428933 |
|
NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions affects activity |
ISO |
styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP1A2 protein] styrofoam analog affects the activity of CYP1A2 protein |
CTD |
PMID:19909766 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
decreases activity multiple interactions |
ISO |
styrofoam analog results in decreased activity of CYP2D6 protein styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP2D6 protein] |
CTD |
PMID:19909766 |
|
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases activity multiple interactions |
ISO |
styrofoam analog results in decreased activity of CYP3A4 protein styrofoam analog promotes the reaction [Cimetidine results in decreased activity of CYP3A4 protein] |
CTD |
PMID:19909766 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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|
G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
styrofoam analog results in increased expression of ITGAM protein |
CTD |
PMID:19428933 |
|
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Pf4 |
platelet factor 4 |
increases secretion |
ISO |
styrofoam analog results in increased secretion of PF4 protein |
CTD |
PMID:19428933 |
|
NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
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|
G |
Ppbp |
pro-platelet basic protein |
increases secretion |
ISO |
styrofoam analog results in increased secretion of PPBP protein |
CTD |
PMID:19428933 |
|
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
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|
G |
Selp |
selectin P |
increases expression |
ISO |
styrofoam results in increased expression of SELP protein |
CTD |
PMID:21123846 |
|
NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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|
G |
Angpt1 |
angiopoietin 1 |
decreases expression |
ISO |
Polyvinyl Chloride results in decreased expression of ANGPT1 mRNA |
CTD |
PMID:12809767 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Cat |
catalase |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of CAT protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT protein]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] which results in decreased expression of CAT protein |
CTD |
PMID:38180308 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of GPT protein |
CTD |
PMID:38180308 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of HMOX1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of HMOX1 protein] |
CTD |
PMID:38180308 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of IL6 protein |
CTD |
PMID:38180308 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 mRNA; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of KEAP1 protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 mRNA]; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein] |
CTD |
PMID:38180308 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in decreased expression of NFE2L2 protein; [[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of NFE2L2 mRNA; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:38180308 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased phosphorylation of RELA protein; [Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased phosphorylation of RELA protein] |
CTD |
PMID:38180308 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[[Microplastics results in increased abundance of [Polyvinyl Chloride co-treated with Polyethylene]] co-treated with [lead acetate results in increased abundance of Lead]] results in increased expression of TNF protein |
CTD |
PMID:38180308 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased expression of APP protein |
CTD |
PMID:35697184 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Atp5mc2 |
ATP synthase membrane subunit c locus 2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of ATP5MC2 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733
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G |
Bola3 |
bolA family member 3 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of BOLA3 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 4:115,853,350...115,862,797
Ensembl chr 4:115,853,350...115,862,797
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
[Silver co-treated with Povidone] affects the expression of CASP3 protein; [Silver co-treated with Povidone] results in decreased expression of CASP3 mRNA |
CTD |
PMID:27387714 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
[Silver co-treated with Povidone] results in decreased expression of CDKN1A mRNA; [Silver co-treated with Povidone] results in decreased expression of CDKN1A protein |
CTD |
PMID:27387714 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of COL8A1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of COX17 mRNA |
CTD |
PMID:25194297 |
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NCBI chr11:62,400,733...62,406,507
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Dad1 |
defender against cell death 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr15:27,677,286...27,697,120
Ensembl chr15:27,677,268...27,697,347
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in decreased expression of DLG4 protein |
CTD |
PMID:35697184 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Gbp2 |
guanylate binding protein 2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of GBP2 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
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G |
H2ax |
H2A.X variant histone |
multiple interactions |
ISO |
[Silver co-treated with Povidone] results in increased expression of H2AX protein modified form |
CTD |
PMID:27387714 |
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NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of HMOX1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of IFIT3 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Lims1 |
LIM zinc finger domain containing 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of LIMS1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500
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G |
Lmnb2 |
lamin B2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of LMNB2 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in decreased expression of MAP2 protein |
CTD |
PMID:35697184 |
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NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased activity of MAPK1 protein |
CTD |
PMID:21729742 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased activity of MAPK3 protein |
CTD |
PMID:21729742 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mdm2 |
MDM2 proto-oncogene |
multiple interactions |
ISO |
[Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA |
CTD |
PMID:27387714 |
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NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] affects the expression of MT1A mRNA |
CTD |
PMID:25194297 |
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NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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G |
Nfix |
nuclear factor I X |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of NFIX mRNA |
CTD |
PMID:25194297 |
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NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of NQO1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nrm |
nurim |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of NRM mRNA |
CTD |
PMID:25194297 |
|
NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802
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G |
Nuak2 |
NUAK family kinase 2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of NUAK2 mRNA |
CTD |
PMID:25194297 |
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NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604
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G |
Ocln |
occludin |
affects expression |
ISO |
Povidone affects the expression of OCLN mRNA |
CTD |
PMID:19729060 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased expression of PINK1 protein |
CTD |
PMID:35697184 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in decreased expression of PPARGC1A protein |
CTD |
PMID:35697184 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased expression of PRKN protein |
CTD |
PMID:35697184 |
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NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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G |
Prpf38b |
pre-mRNA processing factor 38B |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of PRPF38B mRNA |
CTD |
PMID:25194297 |
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NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250
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G |
Prr13 |
proline rich 13 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of PRR13 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005
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G |
Psenen |
presenilin enhancer gamma secretase subunit |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of PSENEN mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of PTGS2 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptk2 |
protein tyrosine kinase 2 |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased activity of PTK2 protein |
CTD |
PMID:21729742 |
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NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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G |
Rab14 |
RAB14, member RAS oncogene family |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of RAB14 mRNA |
CTD |
PMID:25194297 |
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NCBI chr 3:18,501,953...18,523,253
Ensembl chr 3:18,501,963...18,523,172
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G |
Rbm25l1 |
RNA binding motif protein 25-like 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of RBM25L1 mRNA |
CTD |
PMID:25194297 |
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NCBI chr10:10,267,026...10,270,510
Ensembl chr10:10,267,260...10,269,710
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G |
Samd9l |
sterile alpha motif domain containing 9 like |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of SAMD9L mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415
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G |
Selenow |
selenoprotein W |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of SELENOW mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724 Ensembl chr 1:76,598,779...76,604,724
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G |
Slc5a3 |
solute carrier family 5 member 3 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of SLC5A3 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO |
[Silver co-treated with Povidone] results in increased expression of SOD2 mRNA; [Silver co-treated with Povidone] results in increased expression of SOD2 protein |
CTD |
PMID:27387714 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sparc |
secreted protein acidic and cysteine rich |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of SPARC mRNA |
CTD |
PMID:25194297 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Stat2 |
signal transducer and activator of transcription 2 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of STAT2 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
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G |
Sv2b |
synaptic vesicle glycoprotein 2b |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of SV2B mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
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G |
Syp |
synaptophysin |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased expression of SYP protein |
CTD |
PMID:35697184 |
|
NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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G |
Tiparp |
TCDD-inducible poly(ADP-ribose) polymerase |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of TIPARP mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
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G |
Tmtc3 |
transmembrane O-mannosyltransferase targeting cadherins 3 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of TMTC3 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 7:35,264,886...35,310,010
Ensembl chr 7:35,264,892...35,310,385
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
[Silver co-treated with Povidone] affects the phosphorylation of TP53 protein; [Silver co-treated with Povidone] results in decreased expression of TP53 mRNA; [Silver co-treated with Povidone] results in decreased expression of TP53 protein |
CTD |
PMID:27387714 |
|
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Trappc1 |
trafficking protein particle complex subunit 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in decreased expression of TRAPPC1 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr10:54,045,598...54,047,184
Ensembl chr10:54,045,537...54,047,331
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
[Silver Compounds co-treated with Povidone] results in increased expression of VEGFA protein |
CTD |
PMID:21729742 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Wdfy1 |
WD repeat and FYVE domain containing 1 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of WDFY1 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr 9:81,034,852...81,092,823
Ensembl chr 9:81,034,849...81,092,775
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G |
Zfhx3 |
zinc finger homeobox 3 |
multiple interactions |
EXP |
[Silver analog co-treated with Povidone] results in increased expression of ZFHX3 mRNA |
CTD |
PMID:25194297 |
|
NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771
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