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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-adrenergic antagonist
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Accession:CHEBI:37890 term browser browse the term
Definition:An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Synonyms:related_synonym: alpha-adrenergic antagonists;   alpha-adrenergic blocker;   alpha-adrenergic blockers;   alpha-adrenergic receptor blockaders;   alpha-adrenoceptor antagonists


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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19867
        role 19837
          biological role 19835
            pharmacological role 19069
              neurotransmitter agent 16800
                adrenergic agent 9174
                  adrenergic antagonist 2650
                    alpha-adrenergic antagonist 2051
                      2-methoxyidazoxan 4
                      N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine 0
                      N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride 0
                      N-demethylmirtazapine 0
                      ajmalicine 7
                      alfuzosin + 6
                      asenapine 1
                      asenapine maleate 0
                      carvedilol 161
                      cleistanthin A 0
                      cleistanthin B + 0
                      clopenthixol + 1
                      dapiprazole 0
                      desipramine + 51
                      dihydroergocristine mesylate + 0
                      doxazosin + 32
                      ergoloid mesylate 0
                      flupenthixol + 5
                      idazoxan + 14
                      ketanserin 17
                      ketanserin tartrate 0
                      labetalol 13
                      mianserin + 17
                      mirtazapine 38
                      nefazodone + 1757
                      paliperidone 0
                      paliperidone palmitate 15
                      phentolamine 24
                      prazosin + 59
                      prochlorperazine + 3
                      quinidine + 58
                      rac-tamsulosin 0
                      rac-tamsulosin hydrochloride 0
                      risperidone 65
                      roxindole 0
                      sertindole 1
                      setiptiline 0
                      setiptiline maleate 0
                      spiperone 13
                      tamsulosin + 3
                      tamsulosin hydrochloride + 0
                      terazosin + 8
                      thioridazine + 35
                      tolazoline 2
                      yohimbine 52
                      zuclopenthixol 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19867
        role 19837
          application 19682
            pharmaceutical 19517
              drug 19517
                neurotransmitter agent 16800
                  adrenergic agent 9174
                    alpha-adrenergic drug 2558
                      alpha-adrenergic antagonist 2051
                        2-methoxyidazoxan 4
                        N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine 0
                        N-(2,3-dihydro-1,4-benzodioxin-2-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine hydrochloride 0
                        N-demethylmirtazapine 0
                        ajmalicine 7
                        alfuzosin + 6
                        asenapine 1
                        asenapine maleate 0
                        carvedilol 161
                        cleistanthin A 0
                        cleistanthin B + 0
                        clopenthixol + 1
                        dapiprazole 0
                        desipramine + 51
                        dihydroergocristine mesylate + 0
                        doxazosin + 32
                        ergoloid mesylate 0
                        flupenthixol + 5
                        idazoxan + 14
                        ketanserin 17
                        ketanserin tartrate 0
                        labetalol 13
                        mianserin + 17
                        mirtazapine 38
                        nefazodone + 1757
                        paliperidone 0
                        paliperidone palmitate 15
                        phentolamine 24
                        prazosin + 59
                        prochlorperazine + 3
                        quinidine + 58
                        rac-tamsulosin 0
                        rac-tamsulosin hydrochloride 0
                        risperidone 65
                        roxindole 0
                        sertindole 1
                        setiptiline 0
                        setiptiline maleate 0
                        spiperone 13
                        tamsulosin + 3
                        tamsulosin hydrochloride + 0
                        terazosin + 8
                        thioridazine + 35
                        tolazoline 2
                        yohimbine 52
                        zuclopenthixol 0
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