CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: allenes
Accession: CHEBI:37602
browse the term
Definition: Any olefinic compound having two double bonds from one carbon atom to two others.
Synonyms: related_synonym: Formula=C3R4; R2C=C=CR2; SMILES=[*]C([*])=C=C([*])[*]
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Aifm1
apoptosis inducing factor, mitochondria associated 1
affects localization
ISO
neoxanthin affects the localization of AIFM1 protein
CTD
PMID:17186379
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Casp3
caspase 3
multiple interactions
ISO
neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein
CTD
PMID:17186379
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases activity
ISO
neoxanthin results in increased activity of CASP8 protein
CTD
PMID:17186379
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions
ISO
neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein
CTD
PMID:17186379
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Aifm1
apoptosis inducing factor, mitochondria associated 1
affects localization
ISO
neoxanthin affects the localization of AIFM1 protein
CTD
PMID:17186379
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Casp3
caspase 3
multiple interactions
ISO
neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein
CTD
PMID:17186379
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases activity
ISO
neoxanthin results in increased activity of CASP8 protein
CTD
PMID:17186379
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
multiple interactions
ISO
neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein
CTD
PMID:17186379
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Acox1
acyl-CoA oxidase 1
increases expression
ISO
fucoxanthin results in increased expression of ACOX1 mRNA
CTD
PMID:20519145
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acta1
actin, alpha 1, skeletal muscle
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ACTA1 mRNA]
CTD
PMID:33448797
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Adcy7
adenylate cyclase 7
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased methylation of ADCY7 gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of ADCY7 mRNA]
CTD
PMID:33448797
NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
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Ak8
adenylate kinase 8
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA]
CTD
PMID:33448797
NCBI chr 3:12,028,895...12,144,468
Ensembl chr 3:12,028,954...12,144,465
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Akt1
AKT serine/threonine kinase 1
multiple interactions decreases expression
ISO
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein] fucoxanthin results in decreased expression of AKT1 mRNA
CTD
PMID:26418808 PMID:35266250
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alcam
activated leukocyte cell adhesion molecule
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ALCAM mRNA]
CTD
PMID:33448797
NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
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Ankrd61
ankyrin repeat domain 61
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ANKRD61 mRNA]
CTD
PMID:33448797
NCBI chr12:10,718,908...10,723,267
Ensembl chr12:10,718,908...10,723,265
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Arhgdib
Rho GDP dissociation inhibitor beta
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ARHGDIB mRNA]
CTD
PMID:33448797
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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Armcx6
armadillo repeat containing, X-linked 6
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ARMCX6 mRNA]
CTD
PMID:33448797
NCBI chr X:97,929,032...97,932,031
Ensembl chr X:97,929,041...97,931,977
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Atg10
autophagy related 10
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ATG10 mRNA]
CTD
PMID:33448797
NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
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Atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ATP2A1 mRNA]
CTD
PMID:33448797
NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
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Bambi
BMP and activin membrane-bound inhibitor
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of BAMBI mRNA]
CTD
PMID:33448797
NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
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Bche
butyrylcholinesterase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of BCHE mRNA]
CTD
PMID:33448797
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
fucoxanthin results in decreased expression of BCL2 mRNA; fucoxanthin results in decreased expression of BCL2 protein
CTD
PMID:35266250 PMID:38444163
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
multiple interactions decreases expression
ISO
Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; BCL2L1 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]
CTD
PMID:20594983 PMID:38444163
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
fucoxanthin results in decreased expression of BIRC5 protein
CTD
PMID:38444163
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bmp8a
bone morphogenetic protein 8a
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of BMP8B mRNA]
CTD
PMID:33448797
NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
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Casp3
caspase 3
increases cleavage multiple interactions
ISO
fucoxanthin results in increased cleavage of CASP3 protein Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]
CTD
PMID:20594983
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp7
caspase 7
multiple interactions increases cleavage
ISO
Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]
CTD
PMID:20594983
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Casz1
castor zinc finger 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CASZ1 mRNA]
CTD
PMID:33448797
NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400
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Cat
catalase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein]
CTD
PMID:26418808
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccdc116
coiled-coil domain containing 116
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CCDC116 mRNA]
CTD
PMID:33448797
NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607
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Ccr10
C-C motif chemokine receptor 10
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CCR10 mRNA]
CTD
PMID:33448797
NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
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Cd1d1
CD1d1 molecule
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CD1D1 mRNA]
CTD
PMID:33448797
NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CELSR1 mRNA]
CTD
PMID:33448797
NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164
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Cemip
cell migration inducing hyaluronidase 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CEMIP mRNA]
CTD
PMID:33448797
NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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Cfp
complement factor properdin
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CFP mRNA]
CTD
PMID:33448797
NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573
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Cnn1
calponin 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CNN1 mRNA]
CTD
PMID:33448797
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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Col7a1
collagen type VII alpha 1 chain
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of COL7A1 mRNA]
CTD
PMID:33448797
NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
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Cpq
carboxypeptidase Q
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of CPQ mRNA]
CTD
PMID:33448797
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
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Crlf1
cytokine receptor-like factor 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA]
CTD
PMID:33448797
NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA]
CTD
PMID:33448797
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Disp2
dispatched RND transporter family member 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of DISP2 mRNA]
CTD
PMID:33448797
NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:105,762,305...105,777,800
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Dmtn
dematin actin binding protein
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of DMTN mRNA]
CTD
PMID:33448797
NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601
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Drd3
dopamine receptor D3
increases activity
ISO
fucoxanthin results in increased activity of DRD3 protein
CTD
PMID:31323226
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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Drd4
dopamine receptor D4
increases activity
ISO
fucoxanthin results in increased activity of DRD4 protein
CTD
PMID:31323226
NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
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Dusp13b
dual specificity phosphatase 13B
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of DUSP13B mRNA]
CTD
PMID:33448797
NCBI chr15:2,567,432...2,575,105
Ensembl chr15:2,533,547...2,575,539
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Elapor1
endosome-lysosome associated apoptosis and autophagy regulator 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ELAPOR1 mRNA]
CTD
PMID:33448797
NCBI chr 2:196,089,199...196,169,055
Ensembl chr 2:196,091,646...196,168,716
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Esrp1
epithelial splicing regulatory protein 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ESRP1 mRNA]
CTD
PMID:33448797
NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062
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Fam78b
family with sequence similarity 78, member B
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM78B mRNA]
CTD
PMID:33448797
NCBI chr13:79,162,393...79,250,958
Ensembl chr13:79,162,228...79,250,500
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Fam83c
family with sequence similarity 83, member C
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of FAM83C mRNA]
CTD
PMID:33448797
NCBI chr 3:144,333,736...144,339,758
Ensembl chr 3:144,332,982...144,339,802
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Fam98c
family with sequence similarity 98, member C
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM98C mRNA]
CTD
PMID:33448797
NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385
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Fbp2
fructose-bisphosphatase 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FBP2 mRNA]
CTD
PMID:33448797
NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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Fcho1
FCH and mu domain containing endocytic adaptor 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FCHO1 mRNA]
CTD
PMID:33448797
NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
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Fgf1
fibroblast growth factor 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of FGF1 mRNA]
CTD
PMID:33448797
NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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Fgl2
fibrinogen-like 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of FGL2 mRNA]
CTD
PMID:33448797
NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
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Flg
filaggrin
decreases expression
ISO
fucoxanthin results in decreased expression of FLG mRNA
CTD
PMID:27590588
NCBI chr 2:178,884,793...178,912,986
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Gask1b
golgi associated kinase 1B
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of GASK1B mRNA]
CTD
PMID:33448797
NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
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Gja1
gap junction protein, alpha 1
increases expression
ISO
fucoxanthin results in increased expression of GJA1 mRNA; fucoxanthin results in increased expression of GJA1 protein
CTD
PMID:19737546
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
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Gjb1
gap junction protein, beta 1
increases expression
ISO
fucoxanthin results in increased expression of GJB1 mRNA; fucoxanthin results in increased expression of GJB1 protein
CTD
PMID:19737546
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
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Gng2
G protein subunit gamma 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of GNG2 mRNA]
CTD
PMID:33448797
NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
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Gpm6b
glycoprotein m6b
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of GPM6B mRNA]
CTD
PMID:33448797
NCBI chr X:28,057,788...28,204,409
Ensembl chr X:28,059,450...28,204,211
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of GRIN1 mRNA]
CTD
PMID:33448797
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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Gypc
glycophorin C
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of GYPC mRNA]
CTD
PMID:33448797
NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204
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Hhat
hedgehog acyltransferase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of HHAT mRNA]
CTD
PMID:33448797
NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases activity
ISO
fucoxanthin results in decreased activity of HMGCR protein
CTD
PMID:20519145
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmox1
heme oxygenase 1
increases expression
EXP ISO
fucoxanthin results in increased expression of HMOX1 protein
CTD
PMID:23358145
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hunk
hormonally upregulated Neu-associated kinase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of HUNK mRNA]
CTD
PMID:33448797
NCBI chr11:29,641,122...29,758,392
Ensembl chr11:29,640,775...29,757,526
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Ica1l
islet cell autoantigen 1-like
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICA1L mRNA]
CTD
PMID:33448797
NCBI chr 9:61,410,959...61,469,884
Ensembl chr 9:61,412,091...61,470,134
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Icam5
intercellular adhesion molecule 5
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICAM5 mRNA]
CTD
PMID:33448797
NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
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Ifi44
interferon-induced protein 44
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of IFI44 mRNA]
CTD
PMID:33448797
NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
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Il1b
interleukin 1 beta
multiple interactions
ISO
fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]
CTD
PMID:22735499 PMID:35616142
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il23r
interleukin 23 receptor
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL23R mRNA]
CTD
PMID:33448797
NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
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Il24
interleukin 24
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL24 mRNA]
CTD
PMID:33448797
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
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Il6
interleukin 6
multiple interactions
ISO
fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein] fucoxanthin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]
CTD
PMID:22735499 PMID:35616142 PMID:38444163
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Irag1
inositol 1,4,5-triphosphate receptor associated 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of IRAG1 mRNA]
CTD
PMID:33448797
NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
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Irf7
interferon regulatory factor 7
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of IRF7 mRNA]
CTD
PMID:33448797
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
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Jak2
Janus kinase 2
decreases phosphorylation
ISO
fucoxanthin results in decreased phosphorylation of JAK2 protein
CTD
PMID:38444163
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Kcnip2
potassium voltage-gated channel interacting protein 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of KCNIP2 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of KCNIP2 gene]
CTD
PMID:33448797
NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
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Lpcat1
lysophosphatidylcholine acyltransferase 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of LPCAT1 mRNA]
CTD
PMID:33448797
NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
G
Lrrc61
leucine rich repeat containing 61
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of LRRC61 mRNA]
CTD
PMID:33448797
NCBI chr 4:77,503,882...77,523,909
Ensembl chr 4:77,503,857...77,524,020
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Ltc4s
leukotriene C4 synthase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of LTC4S mRNA]
CTD
PMID:33448797
NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
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Ly96
lymphocyte antigen 96
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of LY96 mRNA]
CTD
PMID:33448797
NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
G
Mak
male germ cell-associated kinase
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAK mRNA]
CTD
PMID:33448797
NCBI chr17:23,683,753...23,731,125
Ensembl chr17:23,693,878...23,730,001
G
Mamdc2
MAM domain containing 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAMDC2 mRNA]
CTD
PMID:33448797
NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354
G
Maoa
monoamine oxidase A
decreases activity
ISO
fucoxanthin results in decreased activity of MAOA protein
CTD
PMID:31323226
NCBI chr X:6,032,172...6,098,308
Ensembl chr X:6,030,795...6,099,593
G
Maob
monoamine oxidase B
decreases activity
ISO
fucoxanthin results in decreased activity of MAOB protein
CTD
PMID:31323226
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
G
Map3k13
mitogen-activated protein kinase kinase kinase 13
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA]
CTD
PMID:33448797
NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD
PMID:26418808 PMID:35616142
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD
PMID:26418808 PMID:35616142
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD
PMID:35616142
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
G
Mapk9
mitogen-activated protein kinase 9
multiple interactions
ISO
fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]
CTD
PMID:35616142
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
G
Mcl1
MCL1 apoptosis regulator, BCL2 family member
decreases expression
ISO
fucoxanthin results in decreased expression of MCL1 protein
CTD
PMID:38444163
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
G
Mfsd3
major facilitator superfamily domain containing 3
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA]
CTD
PMID:33448797
NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:108,421,350...108,423,461
G
Mtor
mechanistic target of rapamycin kinase
decreases expression
ISO
fucoxanthin results in decreased expression of MTOR mRNA
CTD
PMID:35266250
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Myo7b
myosin VIIb
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of MYO7B mRNA]
CTD
PMID:33448797
NCBI chr18:23,588,307...23,669,841
Ensembl chr18:23,588,307...23,669,809
G
Nkd2
NKD inhibitor of WNT signaling pathway 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of NKD2 mRNA]
CTD
PMID:33448797
NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
G
Nos2
nitric oxide synthase 2
multiple interactions
ISO
fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein]
CTD
PMID:22735499 PMID:26418808
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
G
Nrbp2
nuclear receptor binding protein 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of NRBP2 mRNA]
CTD
PMID:33448797
NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230
G
Ntm
neurotrimin
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of NTM mRNA]
CTD
PMID:33448797
NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595
G
Nxpe4
neurexophilin and PC-esterase domain family member 4
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of NXPE4 mRNA]
CTD
PMID:33448797
NCBI chr 8:48,502,697...48,744,101
Ensembl chr 8:48,722,440...48,744,100
G
Oas3
2'-5'-oligoadenylate synthetase 3
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of OAS3 mRNA]
CTD
PMID:33448797
NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
G
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of PACSIN1 mRNA]
CTD
PMID:33448797
NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases cleavage
ISO
BCL2L1 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein]
CTD
PMID:38444163
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
G
Pcdh17
protocadherin 17
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDH17 mRNA]
CTD
PMID:33448797
NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999
G
Pip5k1b
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased methylation of PIP5K1B gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of PIP5K1B mRNA]
CTD
PMID:33448797
NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
G
Pitpnm3
PITPNM family member 3
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of PITPNM3 mRNA]
CTD
PMID:33448797
NCBI chr10:56,674,697...56,766,552
Ensembl chr10:56,676,261...56,766,584
G
Ppara
peroxisome proliferator activated receptor alpha
increases expression
ISO
fucoxanthin results in increased expression of PPARA mRNA
CTD
PMID:20519145
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Pparg
peroxisome proliferator-activated receptor gamma
decreases expression
ISO
fucoxanthin results in decreased expression of PPARG mRNA
CTD
PMID:20519145
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Psen2
presenilin 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of PSEN2 mRNA]
CTD
PMID:33448797
NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions
ISO
fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein]
CTD
PMID:22735499 PMID:26418808
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Ptgs2os
prostaglandin-endoperoxide synthase 2, opposite strand
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of PTGS2OS mRNA]
CTD
PMID:33448797
NCBI chr13:62,160,002...62,163,710
G
Rab40b
Rab40b, member RAS oncogene family
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of RAB40B mRNA]
CTD
PMID:33448797
NCBI chr10:106,631,514...106,659,090
Ensembl chr10:106,631,514...106,659,090
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions
ISO
fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]
CTD
PMID:35616142
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Retn
resistin
decreases expression
ISO
fucoxanthin results in decreased expression of RETN protein
CTD
PMID:20519145
NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
G
Rhoa
ras homolog family member A
multiple interactions
ISO
fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased activity of RHOA protein]
CTD
PMID:35616142
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
G
Rtp4
receptor (chemosensory) transporter protein 4
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of RTP4 mRNA]
CTD
PMID:33448797
NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437
G
Shc4
SHC adaptor protein 4
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of SHC4 mRNA]
CTD
PMID:33448797
NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366
G
Slc16a5
solute carrier family 16 member 5
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC16A5 mRNA]
CTD
PMID:33448797
NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
G
Slc18a2
solute carrier family 18 member A2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC18A2 mRNA]
CTD
PMID:33448797
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
G
Slc6a18
solute carrier family 6 member 18
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of SLC6A18 mRNA]
CTD
PMID:33448797
NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925
G
Stat3
signal transducer and activator of transcription 3
multiple interactions decreases phosphorylation
ISO
fucoxanthin inhibits the reaction [IL6 protein results in increased phosphorylation of STAT3 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; STAT3 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein] fucoxanthin results in decreased phosphorylation of STAT3 protein
CTD
PMID:38444163
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Strip2
striatin interacting protein 2
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of STRIP2 mRNA]
CTD
PMID:33448797
NCBI chr 4:58,536,034...58,578,279
Ensembl chr 4:58,536,055...58,578,291
G
Syn1
synapsin I
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYN1 mRNA]
CTD
PMID:33448797
NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
G
Synpo2l
synaptopodin 2-like
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYNPO2L mRNA]
CTD
PMID:33448797
NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429
G
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of TGFB1I1 mRNA]
CTD
PMID:33448797
NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
G
Thsd7a
thrombospondin type 1 domain containing 7A
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of THSD7A mRNA]
CTD
PMID:33448797
NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:40,460,814...40,899,583
G
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEFF1 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of TMEFF1 gene]
CTD
PMID:33448797
NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
G
Tmem229b
transmembrane protein 229B
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEM229B mRNA]
CTD
PMID:33448797
NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:97,775,332...97,819,489
G
Tnf
tumor necrosis factor
multiple interactions
ISO
fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; fucoxanthin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]
CTD
PMID:22735499 PMID:35616142
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfsf13
TNF superfamily member 13
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of TNFSF13 mRNA]
CTD
PMID:33448797
NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
G
Ttc21a
tetratricopeptide repeat domain 21A
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of TTC21A mRNA]
CTD
PMID:33448797
NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:119,666,933...119,702,456
G
Wnt7b
Wnt family member 7B
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of WNT7B mRNA]
CTD
PMID:33448797
NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581
G
Zfp521
zinc finger protein 521
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZFP521 mRNA]
CTD
PMID:33448797
NCBI chr18:4,775,952...5,068,592
Ensembl chr18:4,787,295...5,068,458
G
Zfp566
zinc finger protein 566
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in increased expression of ZFP566 mRNA]
CTD
PMID:33448797
NCBI chr 1:85,318,449...85,342,186
Ensembl chr 1:85,318,452...85,333,161
G
Zxdc
ZXD family zinc finger C
multiple interactions
ISO
fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZXDA mRNA]
CTD
PMID:33448797
NCBI chr 4:122,882,389...122,914,486
Ensembl chr 4:122,882,336...122,916,496
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19880
chemical entity
19878
atom
19878
nonmetal atom
19800
carbon atom
19754
organic molecular entity
19754
olefinic compound
16972
allenes
128
(+)-2,3-dienoyl fatty acyl thioester
0
(+)-4-Acetoxymarilzallene
0
(-)-4-Acetoxymarilzallene, (rel)-
0
(3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al
0
1,2-Di-(9Z,12Z,15Z-octadecatrienoyl)-3-(8-(2E,4Z-decadienoyloxy)-5,6-octadienoyl)-sn-glycerol
0
12-Epoxyobtusallene IV
0
2-oxopenta-3,4-dienoic acid
0
4-[4-(beta-D-glucopyranosyloxy)-2-hydroxy-2,6,6-trimethylcyclohexylidene]-3-Buten-2-one
0
9-oxo-2,4,5,7-decatetraenoic acid
0
Enprostil
0
Marilzallene, (rel)-
0
N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE
0
Obtusallene X, (rel)-
0
allene +
0
allenic fatty acid +
0
alpha-allenylagmatine
0
aplysiallene
0
buta-1,2-diene
0
carbon suboxide
0
citroside B
0
cyclohexa-1,2-diene
0
dinochrome A
0
fucoxanthin
125
grasshopper ketone
0
neoxanthin +
4
peridinin
0
Path 2
CHEBI ontology
19880
subatomic particle
19878
composite particle
19878
hadron
19878
baryon
19878
nucleon
19878
atomic nucleus
19878
atom
19878
main group element atom
19817
p-block element atom
19817
carbon group element atom
19757
carbon atom
19754
organic molecular entity
19754
olefinic compound
16972
allenes
128
(+)-2,3-dienoyl fatty acyl thioester
0
(+)-4-Acetoxymarilzallene
0
(-)-4-Acetoxymarilzallene, (rel)-
0
(3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al
0
1,2-Di-(9Z,12Z,15Z-octadecatrienoyl)-3-(8-(2E,4Z-decadienoyloxy)-5,6-octadienoyl)-sn-glycerol
0
12-Epoxyobtusallene IV
0
2-oxopenta-3,4-dienoic acid
0
4-[4-(beta-D-glucopyranosyloxy)-2-hydroxy-2,6,6-trimethylcyclohexylidene]-3-Buten-2-one
0
9-oxo-2,4,5,7-decatetraenoic acid
0
Enprostil
0
Marilzallene, (rel)-
0
N,N'-BIS(2,3-BUTADIENYL)-1,4-BUTANE-DIAMINE
0
Obtusallene X, (rel)-
0
allene +
0
allenic fatty acid +
0
alpha-allenylagmatine
0
aplysiallene
0
buta-1,2-diene
0
carbon suboxide
0
citroside B
0
cyclohexa-1,2-diene
0
dinochrome A
0
fucoxanthin
125
grasshopper ketone
0
neoxanthin +
4
peridinin
0