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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cinoxacin
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Accession:CHEBI:3716 term browser browse the term
Definition:A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.
Synonyms:exact_synonym: 1-ethyl-4-oxo-1,4-dihydro[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
 related_synonym: 1-ethyl-6,7-methylenedioxy-4(1H)-oxocinnoline-3-carboxylic acid;   5-Ethyl-8-oxo-5,8-dihydro-1,3-dioxa-5,6-diaza-cyclopenta[b]naphthalene-7-carboxylic acid;   Formula=C12H10N2O5;   InChI=1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17);   InChIKey=VDUWPHTZYNWKRN-UHFFFAOYSA-N;   SMILES=CCn1nc(C(O)=O)c(=O)c2cc3OCOc3cc12;   cinoxacine;   cinoxacino;   cinoxacinum
 alt_id: CHEBI:314701
 xref: Beilstein:1084304;   CAS:28657-80-9;   DrugBank:DB00827;   Drug_Central:657;   HMDB:HMDB0014965;   KEGG:D00872;   LINCS:LSM-6552
 xref_mesh: MESH:D002937
 xref: PMID:12204384;   PMID:16295658;   PMID:29438107;   PMID:3005575;   PMID:3147004;   PMID:6226270;   Patent:DE2005104;   Patent:US3669965;   Patent:US6441167;   VSDB:1881;   Wikipedia:Cinoxacin


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cinoxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-Ha RT1 class II, locus Ha affects expression ISO Cinoxacin affects the expression of HLA-DPA1 mRNA CTD PMID:25811541 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244 		JBrowse link
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Term Annotations click to browse term
  CHEBI ontology 19874
    role 19844
      application 19689
        pharmaceutical 19525
          drug 19525
            antiinfective agent 16279
              cinoxacin 1
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Term Annotations click to browse term
  CHEBI ontology 19874
    subatomic particle 19872
      composite particle 19872
        hadron 19872
          baryon 19872
            nucleon 19872
              atomic nucleus 19872
                atom 19872
                  main group element atom 19811
                    p-block element atom 19811
                      carbon group element atom 19751
                        carbon atom 19748
                          organic molecular entity 19748
                            heteroorganic entity 19505
                              organochalcogen compound 19268
                                organooxygen compound 19184
                                  carbon oxoacid 18654
                                    carboxylic acid 18651
                                      oxo carboxylic acid 6316
                                        cinoxacin 1
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