elemental selenium - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	elemental selenium	go back to main search page
Accession:	CHEBI:36904	browse the term
Synonyms:	xref:	CAS:7782-49-2
	xref_mesh:	MESH:D012643

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Genes (1623)

elemental selenium

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 4930523C07 gene

increases expression

Selenium results in increased expression of KIAA0040 mRNA

NCBI chr 1:159,871,950...159,906,157
Ensembl chr 1:159,871,952...159,907,778

G

alpha-2-macroglobulin

increases expression
multiple interactions

Selenium results in increased expression of A2M mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein]

PMID:18997278 PMID:21144892

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

G

angio-associated migratory protein

increases expression

Selenium results in increased expression of AAMP mRNA

NCBI chr 1:74,318,999...74,324,833
Ensembl chr 1:74,318,999...74,323,897

G

aminoadipate-semialdehyde synthase

decreases expression
multiple interactions

Selenium results in decreased expression of AASS mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA

NCBI chr 6:23,072,172...23,132,985
Ensembl chr 6:23,072,172...23,132,985

G

apoptosis antagonizing transcription factor

increases expression

Selenium results in increased expression of AATF mRNA

NCBI chr11:84,313,682...84,404,433
Ensembl chr11:84,313,681...84,404,348

G

ATP-binding cassette, sub-family A member 7

increases expression

Selenium results in increased expression of ABCA7 mRNA

NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406

G

ATP-binding cassette, sub-family member 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]

PMID:11444866 PMID:36464106

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

ATP-binding cassette, sub-family F member 3

increases expression

Selenium results in increased expression of ABCF3 mRNA

NCBI chr16:20,367,309...20,380,357
Ensembl chr16:20,367,327...20,380,129

G

ATP binding cassette subfamily G member 2 (Junior blood group)

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

ATP binding cassette subfamily G member 5

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]

NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439

G

abhydrolase domain containing 17A

increases expression

Selenium results in increased expression of ABHD17A mRNA

NCBI chr10:80,419,483...80,426,199
Ensembl chr10:80,419,488...80,426,175

G

abhydrolase domain containing 2

increases expression

Selenium results in increased expression of ABHD2 mRNA

NCBI chr 7:78,923,002...79,015,257
Ensembl chr 7:78,922,947...79,015,256

G

active BCR-related gene

increases expression

Selenium results in increased expression of ABR mRNA

NCBI chr11:76,307,560...76,468,515
Ensembl chr11:76,307,560...76,514,384

G

acetyl-CoA acyltransferase 2

increases expression

Selenium results in increased expression of ACAA2 mRNA

NCBI chr18:74,912,283...74,939,278
Ensembl chr18:74,912,268...74,939,279

G

acyl-Coenzyme A dehydrogenase, short chain

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Selenium results in increased expression of ACADS mRNA

NCBI chr 5:115,248,358...115,257,405
Ensembl chr 5:115,248,358...115,257,405

G

acetylcholinesterase

multiple interactions

[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium co-treated with Zinc] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in increased activity of ACHE protein; [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in decreased activity of ACHE protein]

PMID:20688495 PMID:37415728

NCBI chr 5:137,286,516...137,292,728
Ensembl chr 5:137,285,781...137,292,728

G

apoptotic chromatin condensation inducer 1

increases expression

Selenium results in increased expression of ACIN1 mRNA

NCBI chr14:54,879,618...54,924,422
Ensembl chr14:54,879,618...54,924,388

G

aconitase 2, mitochondrial

increases expression

Selenium results in increased expression of ACO2 mRNA

NCBI chr15:81,756,664...81,799,338
Ensembl chr15:81,756,510...81,799,334

G

acyl-CoA thioesterase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Selenium results in increased expression of ACOT2 mRNA

NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647

G

acid phosphatase 1, soluble

decreases expression

Selenium results in decreased expression of ACP1 mRNA

NCBI chr12:30,943,325...30,961,616
Ensembl chr12:30,943,325...30,961,588

G

acyl-CoA synthetase long-chain family member 4

multiple interactions

[2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] inhibits the reaction [Aflatoxin B1 results in increased expression of ACSL4 protein]; [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in decreased expression of ACSL4 protein

NCBI chr X:141,100,989...141,173,792
Ensembl chr X:141,100,989...141,173,531

G

actin, beta

increases expression

Selenium results in increased expression of ACTB mRNA

NCBI chr 5:142,888,870...142,892,509
Ensembl chr 5:142,888,870...142,892,509

G

actin, gamma, cytoplasmic 1

increases expression

Selenium results in increased expression of ACTG1 mRNA

NCBI chr11:120,236,513...120,239,321
Ensembl chr11:120,236,516...120,239,368

G

actinin, alpha 1

increases expression

Selenium results in increased expression of ACTN1 mRNA

NCBI chr12:80,214,316...80,307,165
Ensembl chr12:80,214,321...80,307,145

G

actinin alpha 4

increases expression

Selenium results in increased expression of ACTN4 mRNA

NCBI chr 7:28,592,673...28,661,799
Ensembl chr 7:28,592,673...28,661,765

G

ARP1 actin-related protein 1A, centractin alpha

increases expression

Selenium results in increased expression of ACTR1A mRNA

NCBI chr19:46,365,252...46,384,180
Ensembl chr19:46,365,250...46,384,187

G

ARP1 actin-related protein 1B, centractin beta

increases expression

Selenium results in increased expression of ACTR1B mRNA

NCBI chr 1:36,737,195...36,749,051
Ensembl chr 1:36,737,195...36,753,503

G

aminoacylase 1

increases expression

Selenium results in increased expression of ACY1 mRNA

NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518

G

ADAM metallopeptidase with thrombospondin type 1 motif 5

decreases expression

Selenium results in decreased expression of ADAMTS5 mRNA

NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716

G

ArfGAP with dual PH domains 1

increases expression

Selenium results in increased expression of ADAP1 mRNA

NCBI chr 5:139,257,631...139,311,516
Ensembl chr 5:139,257,631...139,311,377

G

adenylate cyclase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA
Selenium results in decreased expression of ADCY2 mRNA

NCBI chr13:68,768,162...69,147,719
Ensembl chr13:68,768,162...69,147,660

G

adenylate cyclase 6

increases expression

Selenium results in increased expression of ADCY6 mRNA

NCBI chr15:98,484,982...98,508,119
Ensembl chr15:98,487,854...98,507,957

G

adducin 1

increases expression

Selenium results in increased expression of ADD1 mRNA

NCBI chr 5:34,731,008...34,789,652
Ensembl chr 5:34,731,008...34,789,652

G

adducin 3

decreases expression

Selenium results in decreased expression of ADD3 mRNA

NCBI chr19:53,128,874...53,235,518
Ensembl chr19:53,128,874...53,235,830

G

adhesion G protein-coupled receptor B1

increases expression

Selenium results in increased expression of ADGRB1 mRNA

NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314

G

adipose secreted signaling protein

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ADISSP mRNA

NCBI chr 2:130,988,235...131,002,001
Ensembl chr 2:130,988,244...131,002,001

G

adenosine A2a receptor

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of ADORA2A mRNA

NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618

G

adrenergic receptor, alpha 2c

increases expression

Selenium results in increased expression of ADRA2C mRNA

NCBI chr 5:35,435,910...35,439,107
Ensembl chr 5:35,435,663...35,439,107

G

adhesion regulating molecule 1 26S proteasome ubiquitin receptor

increases expression

Selenium results in increased expression of ADRM1 mRNA

NCBI chr 2:179,813,381...179,818,076
Ensembl chr 2:179,813,278...179,818,079

G

AE binding protein 2

decreases methylation

Selenium results in decreased methylation of AEBP2 gene

NCBI chr 6:140,567,480...140,624,198
Ensembl chr 6:140,546,644...140,713,010

G

1-acylglycerol-3-phosphate O-acyltransferase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA
Selenium results in increased expression of AGPAT2 mRNA

NCBI chr 2:26,483,069...26,494,429
Ensembl chr 2:26,483,069...26,494,429

G

agrin

increases expression

Selenium results in increased expression of AGRN mRNA

NCBI chr 4:156,249,747...156,281,997
Ensembl chr 4:156,249,747...156,281,945

G

expressed sequence AI837181

increases expression

Selenium results in increased expression of C11ORF68 mRNA

NCBI chr19:5,475,172...5,477,345
Ensembl chr19:5,475,172...5,477,341

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Selenium results in decreased expression of AIMP1 mRNA

NCBI chr 3:132,366,259...132,390,151
Ensembl chr 3:132,366,242...132,390,131

G

aryl-hydrocarbon receptor-interacting protein

increases expression

Selenium results in increased expression of AIP mRNA

NCBI chr19:4,163,756...4,177,233
Ensembl chr19:4,164,446...4,175,858

G

adenylate kinase 1

increases expression

Selenium results in increased expression of AK1 mRNA

NCBI chr 2:32,511,770...32,525,070
Ensembl chr 2:32,511,770...32,525,070

G

adenylate kinase 2

increases expression

Selenium results in increased expression of AK2 mRNA

NCBI chr 4:128,887,017...128,905,322
Ensembl chr 4:128,885,751...128,905,322

G

adenylate kinase 3

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA

NCBI chr19:28,968,715...29,026,122
Ensembl chr19:28,998,233...29,025,361

G

A kinase anchor protein 13

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA

NCBI chr 7:75,105,271...75,404,357
Ensembl chr 7:75,105,282...75,404,357

G

aldo-keto reductase family 1, member C14

increases expression

Selenium deficiency results in increased expression of AKR1C14 mRNA

NCBI chr13:4,099,015...4,140,569
Ensembl chr13:4,099,011...4,140,688

G

thymoma viral proto-oncogene 1

multiple interactions
increases phosphorylation
increases expression
decreases phosphorylation

[Selenium results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]; Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]
Selenium inhibits the reaction [arsenite results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Selenium inhibits the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]
Selenium results in increased phosphorylation of AKT1 protein
Selenium inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
Selenium results in increased expression of AKT1 mRNA

PMID:17339365 PMID:17997286 PMID:19244175 PMID:29324385 PMID:38013145

NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318

G

aminolevulinate, delta-, dehydratase

multiple interactions

Selenium inhibits the reaction [Arsenic results in decreased activity of ALAD protein]

NCBI chr 4:62,422,762...62,438,300
Ensembl chr 4:62,427,406...62,438,155

G

aminolevulinic acid synthase 1

increases expression

Selenium results in increased expression of ALAS1 mRNA

NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853

G

albumin

multiple interactions

[Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of ALB protein]; Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]

PMID:24485406 PMID:37676925

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

activated leukocyte cell adhesion molecule

decreases expression

Selenium results in decreased expression of ALCAM mRNA

NCBI chr16:52,069,359...52,273,444
Ensembl chr16:52,069,359...52,274,437

G

aldehyde dehydrogenase 1 family, member B1

increases expression

Selenium deficiency results in increased expression of ALDH1B1 mRNA

NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604

G

aldehyde dehydrogenase 1 family, member L1

affects expression

Selenium affects the expression of ALDH1L1 protein

NCBI chr 6:90,527,751...90,576,153
Ensembl chr 6:90,463,409...90,577,185

G

aldehyde dehydrogenase 4 family, member A1

increases expression

Selenium results in increased expression of ALDH4A1 mRNA

NCBI chr 4:139,348,404...139,377,002
Ensembl chr 4:139,350,177...139,377,001

G

ALG3 alpha-1,3- mannosyltransferase

increases expression

Selenium results in increased expression of ALG3 mRNA

NCBI chr16:20,424,208...20,429,515
Ensembl chr16:20,424,124...20,430,485

G

ALG9 alpha-1,2-mannosyltransferase

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA

NCBI chr 9:50,686,570...50,754,939
Ensembl chr 9:50,686,319...50,754,842

G

arachidonate 15-lipoxygenase

increases expression
multiple interactions

Selenium deficiency results in increased expression of ALOX15 mRNA
Selenomethionine inhibits the reaction [Selenium deficiency results in increased expression of ALOX15 protein]; Sodium Selenite inhibits the reaction [Selenium deficiency results in increased expression of ALOX15 protein]

PMID:11444866 PMID:34970773

NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857

G

arachidonate 5-lipoxygenase

multiple interactions

[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein

NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139

G

ALS2 C-terminal like

increases expression

Selenium results in increased expression of ALS2CL mRNA

NCBI chr 9:110,709,203...110,729,598
Ensembl chr 9:110,708,938...110,729,598

G

adenosine monophosphate deaminase 3

decreases expression

Selenium results in decreased expression of AMPD3 mRNA

NCBI chr 7:110,367,291...110,411,612
Ensembl chr 7:110,367,413...110,411,612

G

amylase 1, salivary

decreases expression

Selenium results in decreased expression of AMY2A mRNA

NCBI chr 3:113,349,601...113,371,399
Ensembl chr 3:113,349,359...113,400,348

G

anaphase promoting complex C subunit 15

increases expression

Selenium results in increased expression of ANAPC15 mRNA

NCBI chr 7:101,530,508...101,551,056
Ensembl chr 7:101,512,922...101,551,056

G

anaphase promoting complex subunit 2

increases expression

Selenium results in increased expression of ANAPC2 mRNA

NCBI chr 2:25,162,469...25,175,928
Ensembl chr 2:25,162,490...25,175,927

G

angiopoietin 1

decreases expression

Selenium results in decreased expression of ANGPT1 mRNA

NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373

G

ankyrin 3, epithelial

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA

NCBI chr10:69,234,608...69,863,266
Ensembl chr10:69,234,603...69,863,268

G

ankyrin repeat family A member 2

decreases expression

Selenium results in decreased expression of ANKRA2 mRNA

NCBI chr13:98,399,584...98,411,262
Ensembl chr13:98,399,582...98,411,262

G

acidic nuclear phosphoprotein 32 family member B

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA

NCBI chr 4:46,450,926...46,472,657
Ensembl chr 4:46,450,902...46,472,657

G

alanyl aminopeptidase, membrane

increases expression

Selenium results in increased expression of ANPEP mRNA

NCBI chr 7:79,471,551...79,497,958
Ensembl chr 7:79,471,551...79,510,807

G

aldehyde oxidase 1

multiple interactions
decreases expression

Selenium deficiency results in decreased expression of and results in decreased activity of AOX1 protein
Selenium deficiency results in decreased expression of AOX1 mRNA

NCBI chr 1:58,068,963...58,145,569
Ensembl chr 1:58,069,090...58,145,572

G

aldehyde oxidase 3

increases expression

Selenium deficiency results in increased expression of AOX3 mRNA; Selenium results in increased expression of AOX3 mRNA

NCBI chr 1:58,152,294...58,241,380
Ensembl chr 1:58,152,289...58,239,857

G

adaptor protein complex AP-1, beta 1 subunit

increases expression

Selenium results in increased expression of AP1B1 mRNA

NCBI chr11:4,897,320...4,992,731
Ensembl chr11:4,936,824...4,992,791

G

adaptor protein complex AP-1, mu 2 subunit

increases expression

Selenium results in increased expression of AP1M2 mRNA

NCBI chr 9:21,206,753...21,223,617
Ensembl chr 9:21,205,571...21,223,633

G

adaptor-related protein complex 2, alpha 2 subunit

increases expression

Selenium results in increased expression of AP2A2 mRNA

NCBI chr 7:141,142,093...141,212,924
Ensembl chr 7:141,142,086...141,212,924

G

adaptor-related protein complex 2, mu 1 subunit

increases expression

Selenium results in increased expression of AP2M1 mRNA

NCBI chr16:20,354,230...20,363,659
Ensembl chr16:20,354,228...20,363,659

G

adaptor-related protein complex 2, sigma 1 subunit

increases expression

Selenium results in increased expression of AP2S1 mRNA

NCBI chr 7:16,472,369...16,483,215
Ensembl chr 7:16,472,335...16,483,219

G

APC, WNT signaling pathway regulator

decreases expression

Selenium results in decreased expression of APC mRNA

NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605

G

acylpeptide hydrolase

increases expression

Selenium results in increased expression of APEH mRNA

NCBI chr 9:107,962,613...107,971,736
Ensembl chr 9:107,962,612...107,971,805

G

amyloid beta precursor-like protein 2

increases expression

Selenium results in increased expression of APLP2 mRNA

NCBI chr 9:31,060,853...31,123,144
Ensembl chr 9:31,060,853...31,123,111

G

apolipoprotein B

multiple interactions
decreases expression

Selenium inhibits the reaction [Cholesterol results in increased expression of APOB protein]
Selenium results in decreased expression of APOB protein

PMID:16271152 PMID:16581047

NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835

G

apolipoprotein E

increases expression
affects expression

Selenium results in increased expression of APOE mRNA
Selenium affects the expression of APOE protein

PMID:17996733 PMID:19244175

NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113

G

apolipoprotein L 7b

increases expression

Selenium results in increased expression of APOL3 mRNA

NCBI chr15:77,306,409...77,331,660
Ensembl chr15:77,306,409...77,331,692

G

amyloid beta precursor protein

decreases expression

Selenium results in decreased expression of APP mRNA

NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654

G

amyloid beta precursor protein binding protein 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA

NCBI chr11:85,082,134...85,125,946
Ensembl chr11:85,078,088...85,125,956

G

aquaporin 3

increases expression
multiple interactions

Selenium results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA

NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183

G

androgen receptor

multiple interactions
decreases localization
decreases expression

Selenium results in decreased expression of and results in decreased activity of AR protein
Selenium results in decreased localization of AR protein
Selenium results in decreased expression of AR mRNA

PMID:14729601 PMID:16648561

NCBI chr X:97,192,363...97,366,824
Ensembl chr X:97,192,375...97,366,821

G

Araf proto-oncogene, serine/threonine kinase

increases expression
multiple interactions

Selenium results in increased expression of ARAF mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA

NCBI chr X:20,663,946...20,726,760
Ensembl chr X:20,664,053...20,726,758

G

ADP-ribosylation factor 5

increases expression

Selenium results in increased expression of ARF5 mRNA

NCBI chr 6:28,423,603...28,426,601
Ensembl chr 6:28,423,559...28,426,601

G

ADP-ribosylation factor GTPase activating protein 2

increases expression

Selenium results in increased expression of ARFGAP2 mRNA

NCBI chr 2:91,095,460...91,107,716
Ensembl chr 2:91,095,319...91,107,276

G

ADP-ribosylation factor interacting protein 2

increases expression

Selenium results in increased expression of ARFIP2 mRNA

NCBI chr 7:105,283,408...105,289,623
Ensembl chr 7:105,283,410...105,289,623

G

ADP-ribosylation factor related protein 1

increases expression

Selenium results in increased expression of ARFRP1 mRNA

NCBI chr 2:180,999,483...181,007,197
Ensembl chr 2:180,999,483...181,007,197

G

arginase, liver

multiple interactions

2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; 4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; [Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein; [Selenium co-treated with IL4 protein] results in increased expression of ARG1 mRNA; leflunomide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; rosiglitazone promotes the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]

NCBI chr10:24,791,105...24,803,368
Ensembl chr10:24,791,119...24,803,382

G

arginase type II

decreases expression

Selenium results in decreased expression of ARG2 mRNA

NCBI chr12:79,177,562...79,203,075
Ensembl chr12:79,177,551...79,203,075

G

Rho GDP dissociation inhibitor alpha

increases expression

Selenium results in increased expression of ARHGDIA mRNA

NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450

G

ariadne RBR E3 ubiquitin protein ligase 1

decreases expression

Selenium results in decreased expression of ARIH1 mRNA

NCBI chr 9:59,295,837...59,395,469
Ensembl chr 9:59,295,541...59,393,901

G

ADP-ribosylation factor-like 5A

decreases expression

Selenium results in decreased expression of ARL5A mRNA

NCBI chr 2:52,287,961...52,314,886
Ensembl chr 2:52,287,963...52,314,913

G

ADP-ribosylation factor-like 6 interacting protein 4

increases expression

Selenium results in increased expression of ARL6IP4 mRNA

NCBI chr 5:124,254,171...124,256,258
Ensembl chr 5:124,254,152...124,256,259

G

actin related protein 2/3 complex, subunit 1A

increases expression

Selenium results in increased expression of ARPC1A mRNA

NCBI chr 5:145,020,679...145,045,566
Ensembl chr 5:145,020,640...145,045,571

G

actin related protein 2/3 complex, subunit 1B

increases expression

Selenium results in increased expression of ARPC1B mRNA

NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515

G

actin related protein 2/3 complex, subunit 4

increases expression

Selenium results in increased expression of ARPC4 mRNA

NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409

G

arsenite methyltransferase

multiple interactions

Selenium inhibits the reaction [AS3MT protein results in increased methylation of Arsenic]

NCBI chr19:46,695,124...46,729,538
Ensembl chr19:46,695,897...46,729,538

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

increases expression

Selenium results in increased expression of ASAP3 mRNA

NCBI chr 4:135,933,662...135,973,888
Ensembl chr 4:135,933,676...135,972,527

G

ankyrin repeat and SOCS box-containing 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Selenium results in increased expression of ASB1 mRNA

NCBI chr 1:91,467,725...91,487,312
Ensembl chr 1:91,468,266...91,487,311

G

activating signal cointegrator 1 complex subunit 2

increases expression

Selenium results in increased expression of ASCC2 mRNA

NCBI chr11:4,587,698...4,635,699
Ensembl chr11:4,587,747...4,635,699

G

argininosuccinate lyase

increases expression

Selenium results in increased expression of ASL mRNA

NCBI chr 5:130,040,099...130,053,222
Ensembl chr 5:130,040,099...130,058,088

G

argininosuccinate synthetase 1

increases expression

Selenium results in increased expression of ASS1 mRNA

NCBI chr 2:31,360,282...31,410,682
Ensembl chr 2:31,360,219...31,410,684

G

ASXL transcriptional regulator 1

decreases expression

Selenium results in decreased expression of ASXL1 mRNA

NCBI chr 2:153,187,750...153,245,927
Ensembl chr 2:153,187,749...153,245,927

G

ASXL transcriptional regulator 2

decreases expression

Selenium results in decreased expression of ASXL2 mRNA

NCBI chr12:3,476,892...3,560,811
Ensembl chr12:3,476,857...3,556,852

G

activating transcription factor 4

increases expression

Selenium results in increased expression of ATF4 mRNA

NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742

G

activating transcription factor 5

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Selenium results in increased expression of ATF5 mRNA

NCBI chr 7:44,461,680...44,466,082
Ensembl chr 7:44,461,680...44,466,082

G

autophagy related 12

decreases expression

Selenium results in decreased expression of ATG12 mRNA

NCBI chr18:46,865,484...46,874,683
Ensembl chr18:46,863,211...46,874,647

G

autophagy related 13

increases expression

Selenium results in increased expression of ATG13 mRNA

NCBI chr 2:91,504,957...91,540,947
Ensembl chr 2:91,504,963...91,540,921

G

autophagy related 14

decreases expression

Selenium results in decreased expression of ATG14 mRNA

NCBI chr14:47,778,350...47,805,891
Ensembl chr14:47,778,350...47,808,106

G

autophagy related 9A

increases expression

Selenium results in increased expression of ATG9A mRNA

NCBI chr 1:75,157,509...75,168,654
Ensembl chr 1:75,157,504...75,168,840

G

ATM interactor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Selenium results in decreased expression of ATMIN mRNA

NCBI chr 8:117,670,132...117,687,184
Ensembl chr 8:117,670,132...117,687,184

G

ATPase, class V, type 10D

decreases expression

Selenium results in decreased expression of ATP10D mRNA

NCBI chr 5:72,360,672...72,456,114
Ensembl chr 5:72,360,672...72,456,118

G

ATPase, Ca++ transporting, plasma membrane 4

increases expression

Selenium results in increased expression of ATP2B4 mRNA

NCBI chr 1:133,630,416...133,728,755
Ensembl chr 1:133,627,195...133,728,779

G

ATPase, Ca++-sequestering

decreases expression

Selenium results in decreased expression of ATP2C1 mRNA

NCBI chr 9:105,288,561...105,398,456
Ensembl chr 9:105,280,738...105,404,518

G

ATP synthase membrane subunit e

decreases expression

Selenium results in decreased expression of ATP5ME mRNA

NCBI chr 5:108,581,112...108,582,265
Ensembl chr 5:108,581,110...108,582,314

G

ATP synthase peripheral stalk subunit d

decreases expression

Selenium results in decreased expression of ATP5PD mRNA

NCBI chr11:115,306,517...115,310,775
Ensembl chr11:115,306,515...115,310,788

G

ATP synthase peripheral stalk subunit F6

decreases expression

Selenium results in decreased expression of ATP5PF mRNA

NCBI chr16:84,624,754...84,632,495
Ensembl chr16:84,624,754...84,632,513

G

ATPase, H+ transporting, lysosomal accessory protein 1

increases expression

Selenium results in increased expression of ATP6AP1 mRNA

NCBI chr X:73,340,753...73,348,297
Ensembl chr X:73,340,703...73,348,327

G

ATPase, H+ transporting, lysosomal V0 subunit D1

increases expression

Selenium results in increased expression of ATP6V0D1 mRNA

NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679

G

ATPase, H+ transporting, lysosomal V0 subunit E

decreases expression

Selenium results in decreased expression of ATP6V0E mRNA

NCBI chr17:26,895,370...26,918,621
Ensembl chr17:26,882,205...26,918,621

G

ATPase, H+ transporting, lysosomal V1 subunit C1

decreases expression

Selenium results in decreased expression of ATP6V1C1 mRNA

NCBI chr15:38,662,096...38,692,688
Ensembl chr15:38,662,177...38,692,690

G

ATRX, chromatin remodeler

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA
Selenium results in decreased expression of ATRX mRNA

NCBI chr X:104,841,221...104,972,978
Ensembl chr X:104,841,221...104,973,009

G

ataxin 1

decreases expression

Selenium results in decreased expression of ATXN1 mRNA

NCBI chr13:45,703,231...46,118,467
Ensembl chr13:45,703,231...46,118,484

G

ataxin 7

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Selenium results in decreased expression of ATXN7 mRNA

NCBI chr14:8,358,358...8,508,324
Ensembl chr14:8,362,461...8,508,323

G

expressed sequence AU022252

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of C1ORF50 mRNA
Selenium results in decreased expression of C1ORF50 mRNA

NCBI chr 4:119,077,039...119,089,884
Ensembl chr 4:119,060,767...119,089,909

G

AVL9 cell migration associated

decreases expression

Selenium results in decreased expression of AVL9 mRNA

NCBI chr 6:56,691,720...56,738,897
Ensembl chr 6:56,691,884...56,738,897

G

expressed sequence AW209491

decreases expression

Selenium results in decreased expression of C7ORF25 mRNA

NCBI chr13:14,804,830...14,812,787
Ensembl chr13:14,804,739...14,813,681

G

AXL receptor tyrosine kinase

decreases expression

Selenium results in decreased expression of AXL mRNA

NCBI chr 7:25,455,925...25,488,502
Ensembl chr 7:25,456,698...25,488,130

G

beta-1,3-glucuronyltransferase 3

increases expression

Selenium results in increased expression of B3GAT3 mRNA

NCBI chr19:8,897,740...8,904,600
Ensembl chr19:8,897,738...8,904,600

G

BCL2-associated athanogene 1

increases expression

Selenium results in increased expression of BAG1 mRNA

NCBI chr 4:40,936,398...40,948,294
Ensembl chr 4:40,936,398...40,948,294

G

BCL2-associated athanogene 6

increases expression

Selenium results in increased expression of BAG6 mRNA

NCBI chr17:35,354,132...35,366,297
Ensembl chr17:35,354,154...35,366,298

G

Brca1 associated protein 1

increases expression

Selenium results in increased expression of BAP1 mRNA

NCBI chr14:30,973,358...30,981,887
Ensembl chr14:30,973,407...30,981,901

G

BRCA1 associated RING domain 1

decreases expression

Selenium results in decreased expression of BARD1 mRNA

NCBI chr 1:71,066,694...71,142,300
Ensembl chr 1:71,066,657...71,142,305

G

basic leucine zipper transcription factor, ATF-like

increases expression

Selenium results in increased expression of BATF mRNA

NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861

G

BCL2-associated X protein

decreases expression
multiple interactions

Selenium results in decreased expression of BAX protein
Selenium inhibits the reaction [arsenite results in increased expression of BAX protein]
[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]

PMID:16307838 PMID:17997286 PMID:27920530 PMID:29324385

NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322

G

bromodomain adjacent to zinc finger domain, 1B

increases expression

Selenium results in increased expression of BAZ1B mRNA

NCBI chr 5:135,214,094...135,274,985
Ensembl chr 5:135,216,118...135,274,983

G

bobby sox HMG box containing

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Selenium results in decreased expression of BBX mRNA

NCBI chr16:50,012,207...50,252,829
Ensembl chr16:50,012,207...50,252,753

G

cDNA sequence BC028528

decreases expression

Selenium results in decreased expression of C1ORF54 mRNA

NCBI chr 3:95,789,665...95,800,186
Ensembl chr 3:95,791,266...95,799,317

G

BCL11 transcription factor A

decreases expression

Selenium results in decreased expression of BCL11A mRNA

NCBI chr11:24,026,498...24,123,558
Ensembl chr11:24,028,056...24,124,123

G

B cell leukemia/lymphoma 2

decreases expression
multiple interactions

Selenium results in decreased expression of BCL2 protein
Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]

PMID:17523932 PMID:27920530 PMID:34612572

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

BCL2-like 1

increases expression
multiple interactions

Selenium results in increased expression of BCL2L1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA

PMID:11444866 PMID:19244175

NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648

G

BCL2 like 11

multiple interactions
increases expression

BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]
Selenium results in increased expression of BCL2L11 protein

NCBI chr 2:127,967,958...128,004,467
Ensembl chr 2:127,967,958...128,004,467

G

B cell leukemia/lymphoma 3

increases expression

Selenium results in increased expression of BCL3 mRNA

NCBI chr 7:19,542,387...19,556,691
Ensembl chr 7:19,542,387...19,556,695

G

B cell CLL/lymphoma 7B

increases expression

Selenium results in increased expression of BCL7B mRNA

NCBI chr 5:135,197,226...135,210,706
Ensembl chr 5:135,197,137...135,210,709

G

BCL2-associated transcription factor 1

decreases expression
multiple interactions

Selenium results in decreased expression of BCLAF1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of BCLAF1 mRNA

NCBI chr10:20,187,897...20,218,390
Ensembl chr10:20,188,215...20,220,359

G

3-hydroxybutyrate dehydrogenase, type 2

decreases expression

Selenium results in decreased expression of BDH2 mRNA

NCBI chr 3:134,986,982...135,010,187
Ensembl chr 3:134,986,982...135,010,187

G

brain derived neurotrophic factor

multiple interactions
increases expression

Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in decreased expression of BDNF protein]
Selenium results in increased expression of BDNF protein

NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352

G

beclin 1, autophagy related

multiple interactions

Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]; Selenium inhibits the reaction [Acrylamide results in increased expression of BECN1 protein]

PMID:30629952 PMID:37987225

NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112

G

BICD cargo adaptor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA
Selenium results in decreased expression of BICD1 mRNA

NCBI chr 6:149,310,322...149,464,827
Ensembl chr 6:149,310,384...149,464,827

G

BICD family like cargo adaptor 1

increases expression

Selenium results in increased expression of BICDL1 mRNA

NCBI chr 5:115,786,233...115,869,824
Ensembl chr 5:115,786,234...115,869,680

G

BRD4 interacting chromatin remodeling complex associated protein

increases expression

Selenium results in increased expression of BICRA mRNA

NCBI chr 7:15,704,596...15,785,047
Ensembl chr 7:15,704,597...15,781,846

G

BH3 interacting domain death agonist

increases cleavage

Selenium results in increased cleavage of BID protein

NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814

G

bridging integrator 1

increases expression

Selenium results in increased expression of BIN1 mRNA

NCBI chr18:32,509,671...32,568,793
Ensembl chr18:32,510,283...32,568,790

G

baculoviral IAP repeat-containing 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA

NCBI chr 9:7,818,227...7,837,123
Ensembl chr 9:7,818,228...7,837,065

G

baculoviral IAP repeat-containing 5

affects response to substance
multiple interactions

BIRC5 protein affects the susceptibility to Selenium
[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]

PMID:17876054 PMID:27920530

NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569

G

bridge-like lipid transfer protein family member 2

increases expression

Selenium results in increased expression of BLTP2 mRNA

NCBI chr11:78,152,476...78,181,451
Ensembl chr11:78,152,578...78,181,449

G

bridge-like lipid transfer protein family member 3B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BLTP3B mRNA
Selenium results in decreased expression of BLTP3B mRNA

NCBI chr10:89,580,830...89,655,753
Ensembl chr10:89,580,853...89,655,733

G

biliverdin reductase B

increases expression

Selenium results in increased expression of BLVRB mRNA

NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569

G

bromodomain PHD finger transcription factor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Selenium results in decreased expression of BPTF mRNA

NCBI chr11:106,923,907...107,022,982
Ensembl chr11:106,923,907...107,022,953

G

bromodomain containing 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Selenium results in increased expression of BRD2 mRNA

NCBI chr17:34,330,993...34,341,581
Ensembl chr17:34,330,997...34,341,608

G

BRF2, RNA polymerase III transcription initiation factor 50kDa subunit

increases expression

Selenium results in increased expression of BRF2 mRNA

NCBI chr 8:27,613,367...27,618,743
Ensembl chr 8:27,613,392...27,618,708

G

breast cancer metastasis-suppressor 1

increases expression

Selenium results in increased expression of BRMS1 mRNA

NCBI chr19:5,091,391...5,099,940
Ensembl chr19:5,091,382...5,099,945

G

BSCL2 lipid droplet biogenesis associated, seipin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Selenium results in increased expression of BSCL2 mRNA

NCBI chr19:8,814,831...8,826,047
Ensembl chr19:8,814,831...8,826,047

G

bone marrow stromal cell antigen 2

increases expression

Selenium results in increased expression of BST2 mRNA

NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100

G

bystin-like

increases expression

Selenium results in increased expression of BYSL mRNA

NCBI chr17:47,910,256...47,922,417
Ensembl chr17:47,910,256...47,922,417

G

complement component 1, q subcomponent, beta polypeptide

increases expression

Selenium results in increased expression of C1QB mRNA

NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498

G

C2 calcium-dependent domain containing 5

decreases expression

Selenium results in decreased expression of C2CD5 mRNA

NCBI chr 6:142,956,646...143,045,878
Ensembl chr 6:142,956,646...143,045,867

G

expressed sequence C87436

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of C2ORF42 mRNA
Selenium results in decreased expression of C2ORF42 mRNA

NCBI chr 6:86,411,616...86,447,370
Ensembl chr 6:86,415,356...86,450,482

G

calcineurin binding protein 1

increases expression

Selenium results in increased expression of CABIN1 mRNA

NCBI chr10:75,481,944...75,600,194
Ensembl chr10:75,481,946...75,600,175

G

calcium binding and coiled coil domain 1

increases expression

Selenium results in increased expression of CALCOCO1 mRNA

NCBI chr15:102,615,212...102,630,616
Ensembl chr15:102,615,212...102,630,613

G

caldesmon 1

decreases expression

Selenium results in decreased expression of CALD1 mRNA

NCBI chr 6:34,575,433...34,752,404
Ensembl chr 6:34,575,435...34,752,408

G

calcium homeostasis modulator family member 2

increases expression

Selenium results in increased expression of CALHM2 mRNA

NCBI chr19:47,120,671...47,126,733
Ensembl chr19:47,093,792...47,126,733

G

calmodulin 3

increases expression

Selenium results in increased expression of CALM3 mRNA

NCBI chr 7:16,649,304...16,657,957
Ensembl chr 7:16,649,304...16,658,039

G

calreticulin

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Selenium results in decreased expression of CALR mRNA

NCBI chr 8:85,568,717...85,573,560
Ensembl chr 8:85,568,479...85,573,563

G

calumenin

increases expression
multiple interactions

Selenium results in increased expression of CALU mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA

NCBI chr 6:29,348,105...29,376,674
Ensembl chr 6:29,348,068...29,377,109

G

calcium/calmodulin-dependent protein kinase II, beta

increases expression

Selenium results in increased expression of CAMK2B mRNA

NCBI chr11:5,919,642...6,016,401
Ensembl chr11:5,919,644...6,016,362

G

cyclase associated actin cytoskeleton regulatory protein 2

decreases expression

Selenium results in decreased expression of CAP2 mRNA

NCBI chr13:46,655,379...46,803,757
Ensembl chr13:46,655,324...46,803,757

G

capping actin protein, gelsolin like

increases expression

Selenium results in increased expression of CAPG mRNA

NCBI chr 6:72,515,265...72,539,966
Ensembl chr 6:72,521,374...72,539,966

G

calpain 1

increases expression

Selenium results in increased expression of CAPN1 mRNA

NCBI chr19:6,038,573...6,065,855
Ensembl chr19:6,038,573...6,065,927

G

calpain 7

decreases expression

Selenium results in decreased expression of CAPN7 mRNA

NCBI chr14:31,058,582...31,093,944
Ensembl chr14:31,058,595...31,093,943

G

calpain, small subunit 1

increases expression

Selenium results in increased expression of CAPNS1 mRNA

NCBI chr 7:29,886,359...29,898,308
Ensembl chr 7:29,886,361...29,898,236

G

capping actin protein of muscle Z-line subunit beta

increases expression

Selenium results in increased expression of CAPZB mRNA

NCBI chr 4:138,920,210...139,019,131
Ensembl chr 4:138,920,210...139,019,129

G

carbonic anhydrase 3

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA

NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583

G

exon junction complex subunit

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA

NCBI chr11:98,700,634...98,724,633
Ensembl chr11:98,695,731...98,724,640

G

caspase 12

multiple interactions

Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]

NCBI chr 9:5,345,419...5,373,034
Ensembl chr 9:5,345,430...5,373,032

G

caspase 3

decreases activity
multiple interactions
increases activity

Selenium results in decreased activity of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]
[Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; [Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of CASP3 protein]; Selenium inhibits the reaction [arsenite results in increased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]
Selenium results in increased activity of CASP3 protein

PMID:15318939 PMID:17997286 PMID:21628957 PMID:27920530 PMID:29324385 More...

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caspase 8

multiple interactions
increases activity
decreases expression

[Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein]; [Doxorubicin co-treated with Selenium] promotes the reaction [FAS protein binds to CASP8 protein]; Selenium analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA]
Selenium results in increased activity of CASP8 protein
Selenium results in decreased expression of CASP8 mRNA

PMID:12432279 PMID:17970047 PMID:19244175 PMID:27920530

NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662

G

caspase 9

multiple interactions
decreases activity

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]]; [Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]; Selenium analog inhibits the reaction [Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [arsenite results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]
Selenium results in decreased activity of CASP9 protein

PMID:17339365 PMID:17997286 PMID:21628957 PMID:27920530 PMID:29324385 More...

NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287

G

catalase

multiple interactions
increases activity
decreases expression
increases expression

Arsenic promotes the reaction [Selenium results in increased expression of CAT protein]; Fluorides promotes the reaction [Selenium results in increased activity of CAT protein]; Selenium inhibits the reaction [Fluorides results in decreased activity of CAT protein]
Selenium deficiency results in decreased expression of CAT mRNA
[[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Selenium affects the reaction [Clofibrate results in increased activity of CAT protein]; Selenium affects the reaction [Mercury results in decreased activity of CAT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in decreased expression of CAT protein]; Selenium inhibits the reaction [Acrylamide results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in increased activity of CAT protein]; Selenium inhibits the reaction [Chromium results in increased activity of CAT protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Selenium inhibits the reaction [Enrofloxacin results in decreased activity of CAT protein]; Selenium inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Selenium inhibits the reaction [nickel sulfate results in increased activity of CAT protein]; Selenium inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Selenium inhibits the reaction [Potassium Dichromate results in increased activity of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]]

PMID:3456598 PMID:8250967 PMID:11260395 PMID:17512462 PMID:19652462 More...

NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505

G

caveolae associated 1

increases expression

Selenium results in increased expression of CAVIN1 mRNA

NCBI chr11:100,847,562...100,861,443
Ensembl chr11:100,847,559...100,861,713

G

Casitas B-lineage lymphoma b

decreases expression

Selenium results in decreased expression of CBLB mRNA

NCBI chr16:51,851,593...52,028,410
Ensembl chr16:51,851,588...52,028,411

G

chromobox 5

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Selenium results in decreased expression of CBX5 mRNA

NCBI chr15:103,099,973...103,148,337
Ensembl chr15:103,099,971...103,148,243

G

chromobox 7

increases expression

Selenium results in increased expression of CBX7 mRNA

NCBI chr15:79,800,005...79,855,344
Ensembl chr15:79,800,008...79,855,320

G

coiled-coil domain containing 85B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Selenium results in increased expression of DIPA mRNA

NCBI chr19:5,503,191...5,507,591
Ensembl chr19:5,503,208...5,507,922

G

coiled-coil alpha-helical rod protein 1

increases expression

Selenium results in increased expression of CCHCR1 mRNA

NCBI chr17:35,827,914...35,841,912
Ensembl chr17:35,827,997...35,841,912

G

C-C motif chemokine ligand 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of CCL2 mRNA; Selenium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Selenium inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL2 mRNA]

PMID:16143069 PMID:21481475

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

cyclin B1

decreases expression

Selenium deficiency results in decreased expression of CCNB1 mRNA

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

cyclin C

decreases expression

Selenium deficiency results in decreased expression of CCNC mRNA

NCBI chr 4:21,727,705...21,759,917
Ensembl chr 4:21,727,701...21,759,922

G

cyclin D1

increases expression
multiple interactions

Selenium results in increased expression of CCND1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA

PMID:11444866 PMID:19244175

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

cyclin D2

decreases expression

Selenium deficiency results in decreased expression of CCND2 mRNA

NCBI chr 6:127,102,125...127,131,913
Ensembl chr 6:127,102,125...127,129,156

G

cell cycle progression 1

decreases expression

Selenium results in decreased expression of CPR8 mRNA

NCBI chr 9:72,892,692...72,923,622
Ensembl chr 9:72,892,711...72,923,622

G

C-C motif chemokine receptor 3

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CCR3 mRNA

NCBI chr 9:123,817,799...123,831,729
Ensembl chr 9:123,822,009...123,831,726

G

coiled-coil serine rich 2

decreases expression

Selenium results in decreased expression of CCSER2 mRNA

NCBI chr14:36,596,893...36,690,762
Ensembl chr14:36,596,893...36,690,734

G

CD14 antigen

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CD14 mRNA

NCBI chr18:36,858,117...36,859,868
Ensembl chr18:36,858,120...36,859,851

G

CD2 cytoplasmic tail binding protein 2

increases expression

Selenium results in increased expression of CD2BP2 mRNA

NCBI chr 7:126,790,832...126,795,249
Ensembl chr 7:126,790,832...126,795,222

G

CD44 antigen

multiple interactions
increases expression

Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]
Selenium results in increased expression of CD44 mRNA; Selenium results in increased expression of CD44 protein

NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010

G

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

increases expression

Selenium results in increased expression of CD74 mRNA

NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724

G

CD99 antigen

increases expression

Selenium results in increased expression of CD99 mRNA

G

CDC14 cell division cycle 14B

decreases expression

Selenium results in decreased expression of CDC14B mRNA

NCBI chr13:64,337,085...64,423,670
Ensembl chr13:64,337,082...64,423,104

G

CDC16 cell division cycle 16

decreases expression

Selenium results in decreased expression of CDC16 mRNA

NCBI chr 8:13,807,650...13,831,951
Ensembl chr 8:13,807,676...13,831,938

G

CDC23 cell division cycle 23

decreases expression

Selenium results in decreased expression of CDC23 mRNA

NCBI chr18:34,761,401...34,784,802
Ensembl chr18:34,764,004...34,784,788

G

CDC42 binding protein kinase alpha

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CDC42BPA mRNA
Selenium results in decreased expression of CDC42BPA mRNA

NCBI chr 1:179,787,058...179,993,171
Ensembl chr 1:179,788,037...179,993,168

G

CDC42 effector protein 4

increases expression

Selenium results in increased expression of CDC42EP4 mRNA

NCBI chr11:113,617,676...113,643,369
Ensembl chr11:113,617,676...113,642,707

G

cell division cycle 73, Paf1/RNA polymerase II complex component

decreases expression

Selenium results in decreased expression of CDC73 mRNA

NCBI chr 1:143,479,014...143,578,631
Ensembl chr 1:143,474,538...143,578,631

G

cadherin 11

decreases expression

Selenium results in decreased expression of CDH11 mRNA

NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274

G

cadherin 3

increases expression

Selenium results in increased expression of CDH3 mRNA

NCBI chr 8:107,237,484...107,283,543
Ensembl chr 8:107,237,523...107,283,929

G

cyclin dependent kinase 1

decreases expression

Selenium deficiency results in decreased expression of CDK1 mRNA

NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768

G

cyclin dependent kinase 10

increases expression
multiple interactions

Selenium results in increased expression of CDK10 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CDK10 mRNA

NCBI chr 8:123,951,580...123,958,995
Ensembl chr 8:123,951,581...123,958,989

G

cyclin dependent kinase 2

decreases expression

Selenium deficiency results in decreased expression of CDK2 mRNA

NCBI chr10:128,533,807...128,540,920
Ensembl chr10:128,533,808...128,540,900

G

cyclin dependent kinase 2 associated protein 2

increases expression

Selenium results in increased expression of CDK2AP2 mRNA

NCBI chr19:4,146,204...4,149,019
Ensembl chr19:4,147,182...4,149,019

G

cyclin dependent kinase 4

decreases expression
increases expression

Selenium deficiency results in decreased expression of CDK4 mRNA
Selenium results in increased expression of CDK4 mRNA

PMID:11925459 PMID:19244175

NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789

G

cyclin dependent kinase inhibitor 1C

decreases expression

Selenium results in decreased expression of CDKN1C mRNA

NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787

G

CDP-diacylglycerol synthase 1

decreases expression

Selenium results in decreased expression of CDS1 mRNA

NCBI chr 5:101,913,001...101,971,724
Ensembl chr 5:101,912,996...101,971,724

G

CCAAT/enhancer binding protein alpha

increases expression

Selenium results in increased expression of CEBPA mRNA

NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353

G

carboxyl ester lipase

increases expression

Selenium results in increased expression of CEL mRNA

NCBI chr 2:28,445,831...28,453,415
Ensembl chr 2:28,445,807...28,453,415

G

CUGBP, Elav-like family member 2

decreases expression

Selenium results in decreased expression of CELF2 mRNA

NCBI chr 2:6,544,505...7,401,345
Ensembl chr 2:6,544,505...7,514,374

G

centrosomal protein 170

decreases expression

Selenium results in decreased expression of CEP170 mRNA

NCBI chr 1:176,556,638...176,641,545
Ensembl chr 1:176,561,219...176,641,633

G

centrosomal protein 290

decreases expression

Selenium results in decreased expression of CEP290 mRNA

NCBI chr10:100,323,410...100,409,527
Ensembl chr10:100,323,420...100,410,702

G

centrosomal protein 350

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNA
Selenium results in decreased expression of CEP350 mRNA

NCBI chr 1:155,720,710...155,848,976
Ensembl chr 1:155,720,710...155,849,001

G

centrosomal protein 57

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CEP57 mRNA
Selenium results in decreased expression of CEP57 mRNA

NCBI chr 9:13,717,979...13,738,698
Ensembl chr 9:13,719,088...13,738,403

G

ceramide transporter 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CERT1 mRNA
Selenium results in decreased expression of CERT1 mRNA

NCBI chr13:96,679,243...96,782,362
Ensembl chr13:96,679,243...96,776,675

G

carboxylesterase 1D

increases expression

Selenium results in increased expression of CES1 mRNA

NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466

G

complement component factor h

decreases expression

Selenium results in decreased expression of CFH mRNA

NCBI chr 1:140,013,593...140,111,149
Ensembl chr 1:140,012,446...140,111,502

G

CASP8 and FADD-like apoptosis regulator

multiple interactions

[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA]; Selenium analog promotes the reaction [Diazinon results in increased expression of CFLAR mRNA]

NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043

G

chromodomain helicase DNA binding protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of CHD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CHD1 mRNA

NCBI chr17:15,925,229...15,992,874
Ensembl chr17:15,925,229...15,992,872

G

chromodomain helicase DNA binding protein 3

increases expression

Selenium results in increased expression of CHD3 mRNA

NCBI chr11:69,234,099...69,260,325
Ensembl chr11:69,234,099...69,260,232

G

chromodomain helicase DNA binding protein 4

increases expression

Selenium results in increased expression of CHD4 mRNA

NCBI chr 6:125,073,144...125,107,554
Ensembl chr 6:125,072,944...125,107,554

G

chromodomain helicase DNA binding protein 9

decreases expression

Selenium results in decreased expression of CHD9 mRNA

NCBI chr 8:91,554,930...91,781,144
Ensembl chr 8:91,554,980...91,781,144

G

choline kinase alpha

increases expression

Selenium results in increased expression of CHKA mRNA

NCBI chr19:3,901,585...3,944,368
Ensembl chr19:3,901,773...3,944,369

G

charged multivesicular body protein 1A

increases expression

Selenium results in increased expression of CHMP1A mRNA

NCBI chr 8:123,931,000...123,939,527
Ensembl chr 8:123,931,003...123,939,502

G

charged multivesicular body protein 2A

increases expression

Selenium results in increased expression of CHMP2A mRNA

NCBI chr 7:12,765,933...12,768,704
Ensembl chr 7:12,765,937...12,768,734

G

chimerin 2

increases expression

Selenium results in increased expression of CHN2 mRNA

NCBI chr 6:54,016,917...54,278,797
Ensembl chr 6:54,016,539...54,278,795

G

cysteine and histidine rich domain containing 1

decreases expression

Selenium results in decreased expression of CHORDC1 mRNA

NCBI chr 9:18,203,563...18,225,296
Ensembl chr 9:18,203,421...18,228,738

G

chondroitin polymerizing factor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CHPF mRNA
Selenium results in increased expression of CHPF mRNA

NCBI chr 1:75,451,213...75,456,115
Ensembl chr 1:75,451,213...75,455,951

G

cholinergic receptor, nicotinic, alpha polypeptide 4

increases expression

Selenium results in increased expression of CHRNA4 mRNA

NCBI chr 2:180,664,104...180,685,339
Ensembl chr 2:180,660,173...180,685,339

G

cholinergic receptor, nicotinic, epsilon polypeptide

increases expression

Selenium results in increased expression of CHRNE mRNA

NCBI chr11:70,505,709...70,510,074
Ensembl chr11:70,505,709...70,510,042

G

carbohydrate sulfotransferase 3

increases expression

Selenium results in increased expression of CHST3 mRNA

NCBI chr10:60,017,349...60,057,936
Ensembl chr10:60,017,354...60,055,082

G

carbohydrate sulfotransferase 5

increases expression

Selenium results in increased expression of CHST6 mRNA

NCBI chr 8:112,615,767...112,636,831
Ensembl chr 8:112,615,768...112,637,079

G

CDKN1A interacting zinc finger protein 1

increases expression

Selenium results in increased expression of CIZ1 mRNA

NCBI chr 2:32,252,724...32,268,311
Ensembl chr 2:32,242,339...32,270,982

G

cytoskeleton associated protein 2

decreases expression

Selenium results in decreased expression of CKAP2 mRNA

NCBI chr 8:22,658,168...22,675,835
Ensembl chr 8:22,658,176...22,675,835

G

creatine kinase, brain

increases expression

Selenium results in increased expression of CKB mRNA

NCBI chr12:111,635,789...111,638,772
Ensembl chr12:111,635,795...111,638,772

G

CDC28 protein kinase regulatory subunit 2

decreases expression

Selenium results in decreased expression of CKS2 mRNA

NCBI chr13:51,799,268...51,804,698
Ensembl chr13:51,799,268...51,804,696

G

chloride channel CLIC-like 1

decreases expression

Selenium results in decreased expression of CLCC1 mRNA

NCBI chr 3:108,561,194...108,586,156
Ensembl chr 3:108,561,229...108,586,156

G

chloride channel, voltage-sensitive 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLCN3 mRNA
Selenium results in decreased expression of CLCN3 mRNA

NCBI chr 8:61,363,423...61,436,351
Ensembl chr 8:61,363,423...61,436,334

G

claudin 4

increases expression

Selenium results in increased expression of CLDN4 mRNA

NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788

G

claudin 5

multiple interactions

[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; Selenium results in increased expression of and results in increased localization of CLDN5 protein

NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012

G

C-type lectin domain family 3, member b

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TNA mRNA
Selenium results in increased expression of TNA mRNA

NCBI chr 9:122,980,011...122,986,497
Ensembl chr 9:122,980,011...122,986,497

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLN3 mRNA
Selenium results in increased expression of CLN3 mRNA

NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989

G

cleft lip and palate associated transmembrane protein 1

increases expression

Selenium results in increased expression of CLPTM1 mRNA

NCBI chr 7:19,365,505...19,398,955
Ensembl chr 7:19,365,496...19,398,958

G

clathrin light chain B

increases expression

Selenium results in increased expression of CLTB mRNA

NCBI chr13:54,740,199...54,759,186
Ensembl chr13:54,740,214...54,759,157

G

clusterin

increases expression

Selenium results in increased expression of CLU mRNA

NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996

G

C-X9-C motif containing 2

decreases expression

Selenium results in decreased expression of CMC2 mRNA

NCBI chr 8:117,615,424...117,671,061
Ensembl chr 8:117,615,424...117,648,194

G

cornichon family AMPA receptor auxiliary protein 1

decreases expression

Selenium results in decreased expression of CNIH1 mRNA

NCBI chr14:47,013,024...47,025,814
Ensembl chr14:47,013,024...47,025,868

G

cornichon family AMPA receptor auxiliary protein 4

decreases expression

Selenium results in decreased expression of CNIH4 mRNA

NCBI chr 1:180,977,437...180,996,559
Ensembl chr 1:180,972,258...180,996,559

G

calponin 2

increases expression

Selenium results in increased expression of CNN2 mRNA

NCBI chr10:79,824,434...79,831,234
Ensembl chr10:79,824,418...79,831,896

G

calponin 3, acidic

increases expression

Selenium results in increased expression of CNN3 mRNA

NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856

G

CCR4-NOT transcription complex, subunit 8

decreases expression

Selenium results in decreased expression of CNOT8 mRNA

NCBI chr11:57,983,620...58,009,423
Ensembl chr11:57,994,979...58,009,420

G

canopy FGF signaling regulator 2

decreases expression

Selenium results in decreased expression of CNPY2 mRNA

NCBI chr10:128,157,972...128,163,056
Ensembl chr10:128,158,328...128,163,422

G

canopy FGF signaling regulator 3

increases expression

Selenium results in increased expression of CNPY3 mRNA

NCBI chr17:47,046,637...47,063,639
Ensembl chr17:47,046,631...47,063,140

G

component of oligomeric golgi complex 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of COG4 mRNA

NCBI chr 8:111,573,232...111,608,866
Ensembl chr 8:111,573,232...111,608,859

G

component of oligomeric golgi complex 7

increases expression

Selenium results in increased expression of COG7 mRNA

NCBI chr 7:121,522,059...121,580,940
Ensembl chr 7:121,478,586...121,580,934

G

component of oligomeric golgi complex 8

increases expression

Selenium results in increased expression of COG8 mRNA

NCBI chr 8:107,775,341...107,783,369
Ensembl chr 8:107,772,921...107,783,321

G

collagen, type XIV, alpha 1

decreases expression

Selenium results in decreased expression of COL14A1 mRNA

NCBI chr15:55,171,040...55,384,199
Ensembl chr15:55,171,146...55,384,199

G

collagen, type XVIII, alpha 1

increases expression

Selenium results in increased expression of COL18A1 mRNA

NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382

G

collagen, type I, alpha 1

multiple interactions

[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL1A1 protein

NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868

G

collagen, type II, alpha 1

multiple interactions

[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL2A1 protein

NCBI chr15:97,873,483...97,902,525
Ensembl chr15:97,873,483...97,902,576

G

collagen, type IV, alpha 3

decreases expression

Selenium results in decreased expression of COL4A3 mRNA

NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780

G

collagen, type VI, alpha 2

increases expression

Selenium results in increased expression of COL6A2 mRNA

NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464

G

collectin sub-family member 12

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of COLEC12 mRNA

NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644

G

COMM domain containing 3

decreases expression

Selenium results in decreased expression of COMMD3 mRNA

NCBI chr 2:18,677,246...18,681,042
Ensembl chr 2:18,677,234...18,681,042

G

COMM domain containing 4

increases expression

Selenium results in increased expression of COMMD4 mRNA

NCBI chr 9:57,062,319...57,065,633
Ensembl chr 9:57,062,319...57,065,615

G

coatomer protein complex, subunit epsilon

increases expression

Selenium results in increased expression of COPE mRNA

NCBI chr 8:70,755,417...70,765,652
Ensembl chr 8:70,755,168...70,765,643

G

coatomer protein complex, subunit gamma 1

increases expression

Selenium results in increased expression of COPG1 mRNA

NCBI chr 6:87,864,801...87,890,577
Ensembl chr 6:87,864,796...87,890,577

G

COP9 signalosome subunit 7A

increases expression

Selenium results in increased expression of COPS7A mRNA

NCBI chr 6:124,935,413...124,974,866
Ensembl chr 6:124,935,376...124,942,501

G

COP9 signalosome subunit 8

decreases expression

Selenium results in decreased expression of COPS8 mRNA

NCBI chr 1:90,531,147...90,541,063
Ensembl chr 1:90,530,703...90,541,063

G

cytochrome c oxidase subunit 6A1

decreases expression

Selenium results in decreased expression of COX6A1 mRNA

NCBI chr 5:115,483,711...115,487,017
Ensembl chr 5:115,483,701...115,487,040

G

cytochrome c oxidase subunit 7A1

decreases expression

Selenium results in decreased expression of COX7A1 mRNA

NCBI chr 7:29,883,596...29,885,455
Ensembl chr 7:29,883,569...29,885,503

G

cytochrome c oxidase subunit 7A2

decreases expression

Selenium results in decreased expression of COX7A2 mRNA

NCBI chr 9:79,662,523...79,667,135
Ensembl chr 9:79,662,643...79,667,160

G

cytochrome c oxidase subunit 7B

decreases expression

Selenium results in decreased expression of COX7B mRNA

NCBI chr X:105,059,306...105,066,056
Ensembl chr X:105,059,306...105,066,056

G

cytochrome c oxidase subunit 7C

decreases expression

Selenium results in decreased expression of COX7C mRNA

NCBI chr13:86,192,917...86,194,914
Ensembl chr13:86,192,935...86,195,023

G

carboxypeptidase A3, mast cell

decreases expression

Selenium results in decreased expression of CPA3 mRNA

NCBI chr 3:20,269,780...20,296,373
Ensembl chr 3:20,269,784...20,296,345

G

carboxypeptidase D

decreases expression

Selenium results in decreased expression of CPD mRNA

NCBI chr11:76,668,034...76,737,834
Ensembl chr11:76,669,250...76,737,844

G

cleavage and polyadenylation specific factor 1

increases expression

Selenium results in increased expression of CPSF1 mRNA

NCBI chr15:76,480,008...76,491,861
Ensembl chr15:76,480,003...76,491,791

G

cellular retinoic acid binding protein II

increases expression

Selenium deficiency results in increased expression of CRABP2 mRNA

NCBI chr 3:87,856,000...87,860,679
Ensembl chr 3:87,855,973...87,860,683

G

carnitine acetyltransferase

increases expression

Selenium results in increased expression of CRAT mRNA

NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825

G

cereblon

decreases expression

Selenium results in decreased expression of CRBN mRNA

NCBI chr 6:106,755,205...106,777,060
Ensembl chr 6:106,757,162...106,777,038

G

cAMP responsive element binding protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CREB1 mRNA
Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in decreased expression of CREB1 protein]
Selenium results in decreased expression of CREB1 mRNA

PMID:19244175 PMID:30695686

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

G

cAMP responsive element binding protein 3

increases expression

Selenium results in increased expression of CREB3 mRNA

NCBI chr 4:43,562,658...43,567,061
Ensembl chr 4:43,562,332...43,567,060

G

CREB binding protein

decreases expression

Selenium results in decreased expression of CREBBP mRNA

NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861

G

cysteine-rich with EGF-like domains 1

increases expression

Selenium results in increased expression of CRELD1 mRNA

NCBI chr 6:113,460,317...113,470,304
Ensembl chr 6:113,460,258...113,470,304

G

CREB regulated transcription coactivator 1

increases expression

Selenium results in increased expression of CRTC1 mRNA

NCBI chr 8:70,835,002...70,892,720
Ensembl chr 8:70,835,005...70,892,229

G

crystallin beta-gamma domain containing 2

increases expression
multiple interactions

Selenium results in increased expression of CRYBG2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA

NCBI chr 4:133,788,042...133,819,815
Ensembl chr 4:133,788,126...133,819,815

G

colony stimulating factor 1 (macrophage)

increases expression

Selenium results in increased expression of CSF1 mRNA

NCBI chr 3:107,648,364...107,668,048
Ensembl chr 3:107,648,364...107,667,785

G

c-src tyrosine kinase

increases expression

Selenium results in increased expression of CSK mRNA

NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914

G

casein kinase 1, alpha 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1A1 mRNA
Selenium results in decreased expression of CSNK1A1 mRNA

NCBI chr18:61,687,307...61,723,391
Ensembl chr18:61,688,345...61,723,132

G

casein kinase 1, epsilon

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1E mRNA
Selenium results in increased expression of CSNK1E mRNA

NCBI chr15:79,302,054...79,339,779
Ensembl chr15:79,302,056...79,339,767

G

casein kinase 2, alpha 1 polypeptide

decreases expression

Selenium results in decreased expression of CSNK2A1 mRNA

NCBI chr 2:152,068,468...152,123,772
Ensembl chr 2:152,068,759...152,123,772

G

casein kinase 2, beta polypeptide

increases expression

Selenium results in increased expression of CSNK2B mRNA

NCBI chr17:35,335,171...35,341,029
Ensembl chr17:35,335,172...35,341,029

G

chondroitin sulfate proteoglycan 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of CSPG4 mRNA

NCBI chr 9:56,772,388...56,807,154
Ensembl chr 9:56,772,317...56,807,154

G

centrosome and spindle pole associated protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of CSPP1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of CSPP1 mRNA

NCBI chr 1:10,108,194...10,206,996
Ensembl chr 1:10,108,212...10,206,993

G

cystatin C

increases expression

Selenium results in increased expression of CST3 mRNA

NCBI chr 2:148,713,642...148,717,432
Ensembl chr 2:148,713,642...148,717,612

G

cystatin A family member 2

decreases expression

Selenium results in decreased expression of CSTA mRNA

NCBI chr16:36,041,932...36,077,813
Ensembl chr16:36,041,838...36,077,810

G

C-terminal binding protein 1

increases expression

Selenium results in increased expression of CTBP1 mRNA

NCBI chr 5:33,405,067...33,432,348
Ensembl chr 5:33,405,067...33,432,338

G

C-terminal binding protein 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTBP2 mRNA
Selenium results in decreased expression of CTBP2 mRNA

NCBI chr 7:132,588,727...132,726,048
Ensembl chr 7:132,589,292...132,726,083

G

chitobiase

decreases expression

Selenium results in decreased expression of CTBS mRNA

NCBI chr 3:146,156,204...146,171,604
Ensembl chr 3:146,155,550...146,171,604

G

CTD nuclear envelope phosphatase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTDNEP1 mRNA
Selenium results in increased expression of CTDNEP1 mRNA

NCBI chr11:69,871,994...69,881,427
Ensembl chr11:69,871,982...69,881,427

G

catenin alpha 1

increases expression

Selenium results in increased expression of CTNNA1 mRNA

NCBI chr18:35,251,955...35,387,829
Ensembl chr18:35,251,912...35,387,832

G

catenin, beta like 1

increases expression

Selenium results in increased expression of CTNNBL1 mRNA

NCBI chr 2:157,579,321...157,733,823
Ensembl chr 2:157,579,321...157,733,534

G

cathepsin A

increases expression

Selenium results in increased expression of CTSA mRNA

NCBI chr 2:164,674,792...164,682,952
Ensembl chr 2:164,674,793...164,682,952

G

cathepsin B

increases expression

Selenium results in increased expression of CTSB mRNA

NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372

G

cathepsin O

decreases expression

Selenium results in decreased expression of CTSO mRNA

NCBI chr 3:81,839,908...81,864,032
Ensembl chr 3:81,839,908...81,864,032

G

CUE domain containing 2

increases expression

Selenium results in increased expression of CUEDC2 mRNA

NCBI chr19:46,318,251...46,327,144
Ensembl chr19:46,318,251...46,327,141

G

cullin 3

decreases expression

Selenium results in decreased expression of CUL3 mRNA

NCBI chr 1:80,242,640...80,318,426
Ensembl chr 1:80,242,640...80,318,197

G

cullin 4A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of CUL4A mRNA

NCBI chr 8:13,155,623...13,197,940
Ensembl chr 8:13,155,621...13,197,940

G

cullin 7

increases expression

Selenium results in increased expression of CUL7 mRNA

NCBI chr17:46,961,264...46,975,290
Ensembl chr17:46,961,263...46,975,290

G

cutC copper transporter

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CUTC mRNA
Selenium results in decreased expression of CUTC mRNA

NCBI chr19:43,741,462...43,757,077
Ensembl chr19:43,741,435...43,757,077

G

C-X-C motif chemokine ligand 1

increases expression

Selenium results in increased expression of CXCL1 mRNA

NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974

G

C-X-C motif chemokine ligand 15

increases expression

Selenium results in increased expression of CXCL8 mRNA

NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926

G

C-X-C motif chemokine ligand 2

increases expression

Selenium results in increased expression of CXCL2 mRNA

NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797

G

C-X-C motif chemokine ligand 3

increases expression

Selenium results in increased expression of CXCL1 mRNA

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

C-X-C motif chemokine ligand 9

decreases expression

Selenium results in decreased expression of CXCL9 mRNA

NCBI chr 5:92,469,190...92,475,938
Ensembl chr 5:92,469,206...92,475,938

G

C-X-C motif chemokine receptor 4

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of CXCR4 mRNA

NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030

G

CXXC finger protein 1

increases expression

Selenium results in increased expression of CXXC1 mRNA

NCBI chr18:74,349,283...74,354,564
Ensembl chr18:74,349,195...74,354,567

G

cytochrome b-561 domain containing 2

increases expression

Selenium results in increased expression of CYB561D2 mRNA

NCBI chr 9:107,416,210...107,419,392
Ensembl chr 9:107,416,206...107,419,392

G

cytochrome c, somatic

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CYCS mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]

PMID:27920530 PMID:34612572

NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

Selenium inhibits the reaction [Acrylamide results in decreased expression of CYP17A1 mRNA]

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions

Selenium promotes the reaction [Plant Extracts results in increased activity of CYP1A1 protein]

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]

NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986

G

cytochrome P450, family 27, subfamily a, polypeptide 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]

NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051

G

cytochrome P450, family 2, subfamily a, polypeptide 5

increases expression

Selenium deficiency results in increased expression of CYP2A5 mRNA

NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973

G

cytochrome P450, family 2, subfamily b, polypeptide 10

increases expression

Selenium deficiency results in increased expression of CYP2B10 mRNA

NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049

G

cytochrome P450, family 2, subfamily b, polypeptide 9

increases expression

Selenium deficiency results in increased expression of CYP2B9 mRNA

NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086

G

cytochrome P450, family 2, subfamily c, polypeptide 70

increases expression

Selenium deficiency results in increased expression of CYP2C70 mRNA

NCBI chr19:40,141,805...40,175,730
Ensembl chr19:40,141,797...40,175,777

G

cytochrome P450, family 2, subfamily d, polypeptide 13

increases expression

Selenium deficiency results in increased expression of CYP2D13 mRNA; Selenium results in increased expression of CYP2D13 mRNA

NCBI chr15:82,520,951...82,526,246
Ensembl chr15:82,520,388...82,526,247

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 3, subfamily a, polypeptide 11

decreases expression

Selenium results in decreased expression of CYP3A4 mRNA

NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774

G

cytochrome P450, family 3, subfamily a, polypeptide 13

decreases expression

Selenium results in decreased expression of CYP3A5 mRNA

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

cytochrome P450, family 4, subfamily b, polypeptide 1

increases expression

Selenium deficiency results in increased expression of CYP4B1 mRNA

NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920

G

cytochrome P450, family 7, subfamily a, polypeptide 1

multiple interactions

[Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]

PMID:30031400 PMID:36464106

NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633

G

cytochrome P450, family 7, subfamily b, polypeptide 1

increases expression

Selenium deficiency results in increased expression of CYP7B1 mRNA; Selenium results in increased expression of CYP7B1 mRNA

NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502

G

cytochrome P450, family 8, subfamily b, polypeptide 1

increases expression
multiple interactions

Selenium deficiency results in increased expression of CYP8B1 mRNA; Selenium results in increased expression of CYP8B1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]

PMID:16170372 PMID:36464106

NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371

G

RIKEN cDNA D430019H16 gene

decreases expression

Selenium results in decreased expression of C14ORF132 mRNA

NCBI chr12:105,420,115...105,459,354
Ensembl chr12:105,420,115...105,459,354

G

dishevelled associated activator of morphogenesis 1

decreases expression

Selenium results in decreased expression of DAAM1 mRNA

NCBI chr12:71,877,834...72,039,150
Ensembl chr12:71,877,852...72,039,107

G

dishevelled-binding antagonist of beta-catenin 1

decreases expression

Selenium results in decreased expression of DACT1 mRNA

NCBI chr12:71,356,658...71,366,881
Ensembl chr12:71,356,658...71,366,881

G

defender against cell death 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA

NCBI chr14:54,472,942...54,491,386
Ensembl chr14:54,472,936...54,491,561

G

death-associated protein kinase 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA
Selenium results in increased expression of DAPK3 mRNA

NCBI chr10:81,018,821...81,029,031
Ensembl chr10:81,018,839...81,029,031

G

dynactin 1

increases expression

Selenium results in increased expression of DCTN1 mRNA

NCBI chr 6:83,142,702...83,177,103
Ensembl chr 6:83,142,902...83,177,099

G

doublecortin

multiple interactions

[diethyl phosphate co-treated with Cotinine co-treated with bis(2,3,3,3-tetrachloropropyl) ether co-treated with Mercury co-treated with Selenium] results in increased expression of DCX mRNA

NCBI chr X:142,638,838...142,716,392
Ensembl chr X:142,638,838...142,716,307

G

dicarbonyl L-xylulose reductase

increases expression

Selenium results in increased expression of DCXR mRNA

NCBI chr11:120,615,372...120,618,110
Ensembl chr11:120,616,225...120,618,107

G

DDAH family member 2, ADMA independent

increases expression

Selenium results in increased expression of DDAH2 mRNA

NCBI chr17:35,278,011...35,281,075
Ensembl chr17:35,278,011...35,281,071

G

dolichyl-di-phosphooligosaccharide-protein glycotransferase

increases expression

Selenium results in increased expression of DDOST mRNA

NCBI chr 4:138,032,049...138,039,930
Ensembl chr 4:138,032,041...138,039,939

G

DEAD box helicase 17

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DDX17 mRNA
Selenium results in decreased expression of DDX17 mRNA

NCBI chr15:79,411,897...79,430,976
Ensembl chr15:79,411,937...79,430,942

G

DEAD box helicase 18

decreases expression
multiple interactions

Selenium results in decreased expression of DDX18 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA

NCBI chr 1:121,481,564...121,495,709
Ensembl chr 1:121,481,564...121,495,718

G

DEAD box helicase 24

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX24 mRNA
Selenium results in decreased expression of DDX24 mRNA

NCBI chr12:103,374,235...103,392,106
Ensembl chr12:103,374,241...103,392,089

G

DEAD box helicase 39b

decreases expression
increases expression

Selenium results in decreased expression of DDX39B mRNA
Selenium results in increased expression of DDX39B mRNA

NCBI chr17:35,460,722...35,472,683
Ensembl chr17:35,460,722...35,472,683

G

DEAD box helicase 3, Y-linked

decreases expression

Selenium results in decreased expression of DDX3Y mRNA

NCBI chr Y:1,260,715...1,286,630
Ensembl chr Y:1,260,771...1,286,629

G

DEAD box helicase 41

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX41 mRNA
Selenium results in increased expression of DDX41 mRNA

NCBI chr13:55,678,223...55,684,471
Ensembl chr13:55,678,223...55,684,471

G

DEAD box helicase 49

increases expression

Selenium results in increased expression of DDX49 mRNA

NCBI chr 8:70,745,516...70,755,121
Ensembl chr 8:70,745,516...70,755,139

G

2-4-dienoyl-Coenzyme A reductase 2, peroxisomal

increases expression

Selenium deficiency results in increased expression of DECR2 mRNA

NCBI chr17:26,300,182...26,309,096
Ensembl chr17:26,300,182...26,309,311

G

death effector domain-containing

increases expression

Selenium results in increased expression of DEDD mRNA

NCBI chr 1:171,152,229...171,170,843
Ensembl chr 1:171,156,713...171,169,899

G

delta 4-desaturase, sphingolipid 1

decreases expression

Selenium results in decreased expression of DEGS1 mRNA

NCBI chr 1:182,103,529...182,110,366
Ensembl chr 1:182,103,337...182,110,369

G

DENN domain containing 2B

increases expression

Selenium results in increased expression of DENND2B mRNA

NCBI chr 7:109,123,118...109,302,828
Ensembl chr 7:109,123,118...109,302,812

G

deoxyribose-phosphate aldolase

decreases expression

Selenium results in decreased expression of DERA mRNA

NCBI chr 6:137,731,093...137,814,894
Ensembl chr 6:137,731,544...137,834,338

G

desmin

increases expression

Selenium results in increased expression of DES mRNA

NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223

G

desumoylating isopeptidase 2

decreases expression

Selenium results in decreased expression of DESI2 mRNA

NCBI chr 1:178,014,983...178,080,164
Ensembl chr 1:178,014,983...178,084,867

G

DiGeorge syndrome critical region gene 6

increases expression

Selenium results in increased expression of DGCR6 mRNA

NCBI chr16:17,870,736...17,889,497
Ensembl chr16:17,870,724...17,889,496

G

DGCR8, microprocessor complex subunit

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of DGCR8 mRNA
Selenium results in increased expression of DGCR8 mRNA

NCBI chr16:18,071,812...18,107,115
Ensembl chr16:18,071,812...18,107,110

G

24-dehydrocholesterol reductase

increases expression

Selenium results in increased expression of DHCR24 mRNA

NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310

G

7-dehydrocholesterol reductase

increases expression

Selenium results in increased expression of DHCR7 mRNA

NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147

G

deoxyhypusine synthase

increases expression
multiple interactions

Selenium results in increased expression of DHPS mRNA
[Selenium co-treated with Vitamin E] results in increased expression of DHPS mRNA

NCBI chr 8:85,798,106...85,801,790
Ensembl chr 8:85,798,386...85,801,791

G

dehydrogenase/reductase 4

increases expression

Selenium results in increased expression of DHRS4 mRNA

NCBI chr14:55,715,880...55,727,797
Ensembl chr14:55,716,215...55,727,797

G

dehydrogenase/reductase 7B

increases expression

Selenium results in increased expression of DHRS7B mRNA

NCBI chr11:60,721,457...60,749,249
Ensembl chr11:60,721,457...60,751,021

G

DExH-box helicase 30

increases expression

Selenium results in increased expression of DHX30 mRNA

NCBI chr 9:109,913,387...109,946,728
Ensembl chr 9:109,913,388...109,946,898

G

dicer 1, ribonuclease type III

decreases expression

Selenium results in decreased expression of DICER1 mRNA

NCBI chr12:104,654,001...104,718,331
Ensembl chr12:104,654,001...104,718,211

G

deiodinase, iodothyronine, type I

decreases expression
increases expression
affects expression
increases activity
multiple interactions

Selenium deficiency results in decreased expression of DIO1 mRNA
Selenium results in increased expression of DIO1 mRNA
Selenium deficiency affects the expression of DIO1 mRNA
Selenium results in increased activity of DIO1 protein
Selenium inhibits the reaction [Iodine results in decreased activity of DIO1 protein]; Selenium inhibits the reaction [Iodine results in decreased expression of DIO1 mRNA]; Selenium inhibits the reaction [potassium iodate results in decreased activity of DIO1 protein]

PMID:16170372 PMID:16271152 PMID:16874406 PMID:16959840 PMID:17044649 More...

NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366

G

deiodinase, iodothyronine, type II

multiple interactions
increases activity

Selenium results in increased expression of and results in increased activity of DIO2 protein
Selenium results in increased activity of DIO2 protein

PMID:11425850 PMID:15471965

NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812

G

disco interacting protein 2 homolog C

decreases expression

Selenium results in decreased expression of DIP2C mRNA

NCBI chr13:9,326,530...9,718,964
Ensembl chr13:9,326,564...9,718,964

G

discs large MAGUK scaffold protein 1

decreases expression

Selenium results in decreased expression of DLG1 mRNA

NCBI chr16:31,482,261...31,692,174
Ensembl chr16:31,482,261...31,693,947

G

dimethylglycine dehydrogenase precursor

affects abundance

DMGDH gene SNP affects the abundance of Selenium

NCBI chr13:93,810,944...93,889,331
Ensembl chr13:93,810,941...93,889,341

G

cyclin D binding myb like transcription factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DMTF1 mRNA
Selenium results in decreased expression of DMTF1 mRNA

NCBI chr 5:9,168,868...9,211,782
Ensembl chr 5:9,168,801...9,211,776

G

dystrophia myotonica-containing WD repeat motif

increases expression

Selenium results in increased expression of DMWD mRNA

NCBI chr 7:18,810,002...18,816,701
Ensembl chr 7:18,810,152...18,816,701

G

Dmx-like 2

decreases expression

Selenium results in decreased expression of DMXL2 mRNA

NCBI chr 9:54,272,442...54,409,150
Ensembl chr 9:54,272,442...54,408,910

G

DNA replication helicase/nuclease 2

decreases expression

Selenium results in decreased expression of DNA2 mRNA

NCBI chr10:62,782,762...62,809,967
Ensembl chr10:62,782,805...62,809,964

G

DnaJ heat shock protein family (Hsp40) member A3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA
Selenium results in decreased expression of DNAJA3 mRNA

NCBI chr16:4,501,934...4,525,559
Ensembl chr16:4,457,853...4,525,559

G

DnaJ heat shock protein family (Hsp40) member B3

multiple interactions
decreases expression

[Selenium co-treated with Selenium] results in decreased expression of DNAJB3 mRNA
Selenium deficiency results in decreased expression of DNAJB3 mRNA

NCBI chr 1:88,132,454...88,133,470
Ensembl chr 1:88,132,454...88,133,504

G

DnaJ heat shock protein family (Hsp40) member B4

decreases expression

Selenium results in decreased expression of DNAJB4 mRNA

NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939

G

DnaJ heat shock protein family (Hsp40) member C2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC2 mRNA

NCBI chr 5:21,962,279...21,990,183
Ensembl chr 5:21,962,265...21,990,249

G

DnaJ heat shock protein family (Hsp40) member C7

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC7 mRNA

NCBI chr11:100,473,644...100,511,030
Ensembl chr11:100,473,644...100,511,014

G

DnaJ heat shock protein family (Hsp40) member C9

decreases expression

Selenium results in decreased expression of DNAJC9 mRNA

NCBI chr14:20,434,706...20,438,978
Ensembl chr14:20,434,706...20,438,978

G

DNA methyltransferase 1

affects activity

Selenium affects the activity of DNMT1 protein

NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184

G

aspartyl aminopeptidase

increases expression

Selenium results in increased expression of DNPEP mRNA

NCBI chr 1:75,285,209...75,294,648
Ensembl chr 1:75,284,540...75,294,634

G

deoxyhypusine hydroxylase/monooxygenase

increases expression
multiple interactions

Selenium results in increased expression of DOHH mRNA
[Selenium co-treated with Vitamin E] results in increased expression of DOHH mRNA

NCBI chr10:81,220,268...81,224,186
Ensembl chr10:81,220,262...81,224,186

G

dolichyl pyrophosphate phosphatase 1

increases expression

Selenium results in increased expression of DOLPP1 mRNA

NCBI chr 2:30,282,261...30,290,539
Ensembl chr 2:30,282,266...30,290,541

G

dihydropyrimidine dehydrogenase

decreases expression

Selenium results in decreased expression of DPYD mRNA

NCBI chr 3:118,355,758...119,226,573
Ensembl chr 3:118,355,778...119,226,573

G

down-regulator of transcription 1

decreases expression

Selenium results in decreased expression of DR1 mRNA

NCBI chr 5:108,416,763...108,428,387
Ensembl chr 5:108,416,763...108,428,392

G

developmentally regulated GTP binding protein 2

increases expression

Selenium results in increased expression of DRG2 mRNA

NCBI chr11:60,345,442...60,359,589
Ensembl chr11:60,345,417...60,359,580

G

desmocollin 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DSC2 mRNA
Selenium results in decreased expression of DSC2 mRNA

NCBI chr18:20,163,690...20,192,611
Ensembl chr18:20,163,690...20,192,611

G

dermatan sulfate epimerase

decreases expression

Selenium results in decreased expression of DSE mRNA

NCBI chr10:34,027,385...34,084,267
Ensembl chr10:34,027,389...34,083,711

G

dual oxidase 1

increases expression

Selenium results in increased expression of DUOX1 mRNA

NCBI chr 2:122,143,525...122,178,454
Ensembl chr 2:122,146,153...122,178,453

G

dual specificity phosphatase 8

increases expression

Selenium results in increased expression of DUSP8 mRNA

NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580

G

decapping exoribonuclease

increases expression

Selenium results in increased expression of DXO mRNA

NCBI chr17:35,055,998...35,058,162
Ensembl chr17:35,055,995...35,058,209

G

dymeclin

decreases expression

Selenium results in decreased expression of DYM mRNA

NCBI chr18:75,151,772...75,420,037
Ensembl chr18:75,151,852...75,420,035

G

dynein cytoplasmic 1 heavy chain 1

increases expression

Selenium results in increased expression of DYNC1H1 mRNA

NCBI chr12:110,567,829...110,633,378
Ensembl chr12:110,567,886...110,633,379

G

dynein light chain roadblock-type 1

decreases expression

Selenium results in decreased expression of DYNLRB1 mRNA

NCBI chr 2:155,078,453...155,092,197
Ensembl chr 2:155,078,453...155,092,197

G

E2F transcription factor 1

increases expression

Selenium results in increased expression of E2F1 mRNA

NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812

G

E2F transcription factor 4

increases expression

Selenium results in increased expression of E2F4 mRNA

NCBI chr 8:106,024,295...106,032,002
Ensembl chr 8:106,024,295...106,032,002

G

E2F transcription factor 6

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of E2F6 mRNA
Selenium results in decreased expression of E2F6 mRNA

NCBI chr12:16,860,932...16,876,753
Ensembl chr12:16,860,964...16,889,743

G

E4F transcription factor 1

increases expression

Selenium results in increased expression of E4F1 mRNA

NCBI chr17:24,662,752...24,674,366
Ensembl chr17:24,662,752...24,689,287

G

extracellular matrix protein 2, female organ and adipocyte specific

decreases expression

Selenium results in decreased expression of ECM2 mRNA

NCBI chr13:49,658,259...49,686,267
Ensembl chr13:49,658,286...49,686,265

G

ECSIT signalling integrator

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ECSIT mRNA
Selenium results in increased expression of ECSIT mRNA

NCBI chr 9:21,982,731...21,997,648
Ensembl chr 9:21,983,542...21,996,734

G

endothelial differentiation-related factor 1

increases expression

Selenium results in increased expression of EDF1 mRNA

NCBI chr 2:25,447,838...25,452,096
Ensembl chr 2:25,447,859...25,452,094

G

endothelin receptor type A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of EDNRA mRNA
Selenium results in decreased expression of EDNRA mRNA

NCBI chr 8:78,389,658...78,451,081
Ensembl chr 8:78,389,660...78,451,093

G

eukaryotic translation elongation factor 1 alpha 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EEF1A2 mRNA
Selenium results in increased expression of EEF1A2 mRNA

NCBI chr 2:180,783,551...180,798,808
Ensembl chr 2:180,789,446...180,798,807

G

eukaryotic translation elongation factor 1 delta

increases expression

Selenium results in increased expression of EEF1D mRNA

NCBI chr15:75,766,643...75,781,425
Ensembl chr15:75,766,054...75,781,405

G

EF-hand calcium binding domain 14

increases expression

Selenium results in increased expression of EFCAB14 mRNA

NCBI chr 4:115,594,914...115,634,590
Ensembl chr 4:115,594,941...115,634,524

G

epidermal growth factor-containing fibulin-like extracellular matrix protein 2

increases expression

Selenium results in increased expression of EFEMP2 mRNA

NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545

G

EF-hand domain (C-terminal) containing 1

decreases expression

Selenium results in decreased expression of EFHC1 mRNA

NCBI chr 1:21,021,776...21,061,065
Ensembl chr 1:21,021,850...21,061,065

G

EF hand domain containing 2

increases expression

Selenium results in increased expression of EFHD2 mRNA

NCBI chr 4:141,585,453...141,602,231
Ensembl chr 4:141,585,453...141,602,231

G

epidermal growth factor

multiple interactions

Selenium inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Selenium inhibits the reaction [EGF protein results in increased abundance of Peroxides]

NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965

G

epidermal growth factor receptor

decreases expression

Selenium results in decreased expression of EGFR mRNA

NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158

G

early growth response 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of EGR1 mRNA

NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037

G

EH domain binding protein 1

decreases expression

Selenium results in decreased expression of EHBP1 mRNA

NCBI chr11:21,955,825...22,237,086
Ensembl chr11:21,955,828...22,292,292

G

EH-domain containing 2

increases expression

Selenium results in increased expression of EHD2 mRNA

NCBI chr 7:15,680,883...15,701,402
Ensembl chr 7:15,680,883...15,701,492

G

eukaryotic translation initiation factor 1B

decreases expression

Selenium results in decreased expression of EIF1B mRNA

NCBI chr 9:120,321,672...120,324,393
Ensembl chr 9:120,321,298...120,324,396

G

eukaryotic translation initiation factor 2-alpha kinase 2

decreases expression

Selenium results in decreased expression of EIF2AK2 mRNA

NCBI chr17:79,157,933...79,190,001
Ensembl chr17:79,159,993...79,190,002

G

eukaryotic translation initiation factor 3, subunit A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of EIF3A mRNA

NCBI chr19:60,749,554...60,779,131
Ensembl chr19:60,749,555...60,779,096

G

eukaryotic translation initiation factor 3, subunit B

increases expression

Selenium results in increased expression of EIF3B mRNA

NCBI chr 5:140,405,060...140,429,113
Ensembl chr 5:140,405,083...140,429,115

G

eukaryotic translation initiation factor 3, subunit C

increases expression

Selenium results in increased expression of EIF3C mRNA

NCBI chr 7:126,146,083...126,165,538
Ensembl chr 7:126,145,627...126,165,583

G

eukaryotic translation initiation factor 4, gamma 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EIF4G1 mRNA
Selenium results in increased expression of EIF4G1 mRNA

NCBI chr16:20,491,457...20,511,633
Ensembl chr16:20,487,063...20,511,634

G

eukaryotic translation initiation factor 5A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of EIF5A mRNA

NCBI chr11:69,807,538...69,812,784
Ensembl chr11:69,807,540...69,812,784

G

eukaryotic translation initiation factor 5B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IF2 mRNA
Selenium results in decreased expression of IF2 mRNA

NCBI chr 1:38,037,091...38,094,660
Ensembl chr 1:38,037,091...38,094,660

G

eukaryotic translation initiation factor 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EIF6 mRNA
Selenium results in increased expression of EIF6 mRNA

NCBI chr 2:155,661,757...155,668,845
Ensembl chr 2:155,661,752...155,668,845

G

elongin A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ELOA mRNA

NCBI chr 4:135,730,681...135,748,960
Ensembl chr 4:135,730,679...135,749,074

G

elongator complex protein 1

decreases expression

Selenium results in decreased expression of ELP1 mRNA

NCBI chr 4:56,746,547...56,802,565
Ensembl chr 4:56,749,680...56,802,331

G

ER membrane protein complex subunit 9

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of EMC9 mRNA

NCBI chr14:55,818,976...55,822,832
Ensembl chr14:55,818,973...55,822,759

G

elastin microfibril interfacer 1

increases expression

Selenium results in increased expression of EMILIN1 mRNA

NCBI chr 5:31,070,729...31,078,623
Ensembl chr 5:31,070,746...31,078,621

G

echinoderm microtubule associated protein like 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EML2 mRNA
Selenium results in increased expression of EML2 mRNA

NCBI chr 7:18,910,322...18,940,407
Ensembl chr 7:18,910,346...18,940,407

G

epithelial membrane protein 2

increases expression

Selenium results in increased expression of EMP2 mRNA

NCBI chr16:10,099,613...10,131,832
Ensembl chr16:10,099,613...10,131,832

G

epithelial membrane protein 3

increases expression

Selenium results in increased expression of EMP3 mRNA

NCBI chr 7:45,567,447...45,570,850
Ensembl chr 7:45,567,447...45,570,828

G

EMSY, BRCA2-interacting transcriptional repressor

decreases expression

Selenium results in decreased expression of EMSY mRNA

NCBI chr 7:98,236,344...98,308,779
Ensembl chr 7:98,236,344...98,305,990

G

endonuclease G

increases expression

Selenium results in increased expression of ENDOG mRNA

NCBI chr 2:30,061,525...30,064,057
Ensembl chr 2:30,061,505...30,064,081

G

endoglin

increases expression

Selenium results in increased expression of ENG mRNA

NCBI chr 2:32,536,607...32,572,681
Ensembl chr 2:32,536,607...32,572,681

G

enolase 2, gamma neuronal

increases expression

Selenium results in increased expression of ENO2 mRNA

NCBI chr 6:124,737,018...124,746,489
Ensembl chr 6:124,737,016...124,746,636

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

Selenium results in decreased expression of ENPP1 mRNA

NCBI chr10:24,513,812...24,588,057
Ensembl chr10:24,513,812...24,588,057

G

endothelium and lymphocyte associated ASCH domain 1

decreases expression

Selenium results in decreased expression of EOLA1 mRNA

NCBI chr X:69,429,519...69,433,022
Ensembl chr X:69,429,483...69,433,023

G

erythrocyte membrane protein band 4.1 like 4b

decreases expression

Selenium results in decreased expression of EPB41L4B mRNA

NCBI chr 4:56,991,977...57,143,753
Ensembl chr 4:56,991,972...57,143,437

G

Eph receptor B6

increases expression

Selenium results in increased expression of EPHB6 mRNA

NCBI chr 6:41,581,940...41,597,445
Ensembl chr 6:41,582,416...41,597,443

G

epoxide hydrolase 2, cytoplasmic

increases expression

Selenium results in increased expression of EPHX2 mRNA

NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949

G

epsin 2

increases expression

Selenium results in increased expression of EPN2 mRNA

NCBI chr11:61,406,709...61,470,560
Ensembl chr11:61,408,075...61,470,513

G

erb-b2 receptor tyrosine kinase 2

increases expression
multiple interactions

Selenium results in increased expression of ERBB2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA

NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542

G

excision repair cross-complementing rodent repair deficiency, complementation group 1

increases expression

Selenium results in increased expression of ERCC1 mRNA

NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449

G

ERGIC and golgi 3

increases expression

Selenium results in increased expression of ERGIC3 mRNA

NCBI chr 2:155,849,948...155,860,199
Ensembl chr 2:155,849,965...155,860,199

G

estrogen receptor 1 (alpha)

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA]

NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614

G

epithelial splicing regulatory protein 2

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ESRP2 mRNA

NCBI chr 8:106,856,658...106,863,825
Ensembl chr 8:106,856,951...106,863,606

G

ess-2 splicing factor

increases expression

Selenium results in increased expression of ESS2 mRNA

NCBI chr16:17,718,573...17,729,225
Ensembl chr16:17,718,573...17,729,212

G

EvC ciliary complex subunit 1

increases expression

Selenium results in increased expression of EVC mRNA

NCBI chr 5:37,446,314...37,495,489
Ensembl chr 5:37,446,442...37,494,238

G

ecotropic viral integration site 5

decreases expression

Selenium results in decreased expression of EVI5 mRNA

NCBI chr 5:107,892,661...108,022,973
Ensembl chr 5:107,892,661...108,022,973

G

Ewing sarcoma breakpoint region 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EWSR1 mRNA
Selenium results in increased expression of EWSR1 mRNA

NCBI chr11:5,019,687...5,049,314
Ensembl chr11:5,019,689...5,049,266

G

exocyst complex component 3

increases expression

Selenium results in increased expression of SEC6 mRNA

NCBI chr13:74,317,921...74,358,151
Ensembl chr13:74,317,607...74,356,851

G

exosome component 4

increases expression

Selenium results in increased expression of EXOSC4 mRNA

NCBI chr15:76,211,597...76,214,870
Ensembl chr15:76,211,597...76,214,877

G

exosome component 8

decreases expression

Selenium results in decreased expression of EXOSC8 mRNA

NCBI chr 3:54,636,099...54,642,469
Ensembl chr 3:54,636,099...54,642,814

G

exostosin glycosyltransferase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of EXT1 mRNA

NCBI chr15:52,931,657...53,209,579
Ensembl chr15:52,927,434...53,209,555

G

exostosin glycosyltransferase 2

decreases expression

Selenium results in decreased expression of EXT2 mRNA

NCBI chr 2:93,525,978...93,652,913
Ensembl chr 2:93,491,373...93,652,913

G

EYA transcriptional coactivator and phosphatase 2

increases expression

Selenium results in increased expression of EYA2 mRNA

NCBI chr 2:165,436,892...165,613,645
Ensembl chr 2:165,436,952...165,613,647

G

ezrin

decreases expression
multiple interactions

Selenium results in decreased expression of EZR mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of EZR mRNA

NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183

G

F11 receptor

increases expression

Selenium results in increased expression of F11R mRNA

NCBI chr 1:171,265,129...171,292,161
Ensembl chr 1:171,265,103...171,292,171

G

coagulation factor II thrombin receptor

decreases expression
multiple interactions

Selenium results in decreased expression of F2R mRNA
[Selenium co-treated with Vitamin E] results in increased expression of F2R mRNA

NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995

G

fatty acid amide hydrolase

increases expression

Selenium results in increased expression of FAAH mRNA

NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123

G

Fas associated via death domain

multiple interactions
increases expression

[Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein]; [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FADD mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of FADD mRNA]
Selenium results in increased expression of FADD protein

PMID:17970047 PMID:27920530

NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200

G

fatty acid desaturase 3

increases expression

Selenium results in increased expression of FADS3 mRNA

NCBI chr19:10,018,189...10,037,477
Ensembl chr19:10,018,933...10,037,474

G

family with sequence similarity 107, member A

increases expression

Selenium results in increased expression of FAM107A mRNA

NCBI chr14:14,152,166...14,173,503
Ensembl chr14:14,151,750...14,173,499

G

family with sequence similarity 111, member A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FAM111A mRNA
Selenium results in decreased expression of FAM111A mRNA

NCBI chr19:12,550,874...12,567,133
Ensembl chr19:12,523,104...12,567,132

G

family with sequence similarity 149, member A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FAM149A mRNA
Selenium results in decreased expression of FAM149A mRNA

NCBI chr 8:45,789,752...45,835,328
Ensembl chr 8:45,789,754...45,835,328

G

family with sequence similarity 32, member A

increases expression

Selenium results in increased expression of FAM32A mRNA

NCBI chr 8:72,973,589...72,978,878
Ensembl chr 8:72,973,574...72,978,262

G

FAM3 metabolism regulating signaling molecule A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FAM3A mRNA
Selenium results in increased expression of FAM3A mRNA

NCBI chr X:73,427,816...73,436,856
Ensembl chr X:73,428,325...73,436,878

G

family with sequence similarity 50, member A

increases expression

Selenium results in increased expression of FAM50A mRNA

NCBI chr X:73,356,589...73,363,761
Ensembl chr X:73,356,639...73,363,755

G

family with sequence similarity 53, member B

increases expression

Selenium results in increased expression of FAM53B mRNA

NCBI chr 7:132,313,813...132,429,518
Ensembl chr 7:132,313,811...132,415,615

G

FANCD2/FANCI-associated nuclease 1

decreases expression

Selenium results in decreased expression of FAN1 mRNA

NCBI chr 7:63,994,627...64,023,874
Ensembl chr 7:63,996,506...64,023,843

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

increases expression

Selenium results in increased expression of FARP1 mRNA

NCBI chr14:121,272,563...121,521,156
Ensembl chr14:121,272,612...121,521,156

G

phenylalanyl-tRNA synthetase, alpha subunit

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of FARSA mRNA
Selenium results in increased expression of FARSA mRNA

NCBI chr 8:85,583,597...85,595,886
Ensembl chr 8:85,583,618...85,595,886

G

Fas cell surface death receptor

multiple interactions

[Doxorubicin co-treated with Selenium] promotes the reaction [FAS protein binds to CASP8 protein]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of FAS mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of FAS mRNA]

PMID:17970047 PMID:27920530

NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172

G

Fas ligand

multiple interactions

[Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA]

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

fatty acid synthase

increases expression
multiple interactions

Selenium results in increased expression of FASN mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]

PMID:19022953 PMID:19244175 PMID:36464106

NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373

G

FAT atypical cadherin 4

decreases expression

Selenium results in decreased expression of FAT4 mRNA

NCBI chr 3:38,939,867...39,066,134
Ensembl chr 3:38,941,089...39,066,134

G

fatty acid hydroxylase domain containing 2

decreases expression

Selenium results in decreased expression of FAXDC2 mRNA

NCBI chr11:57,954,508...57,983,977
Ensembl chr11:57,954,378...57,983,960

G

fibulin 1

increases expression

Selenium results in increased expression of FBLN1 mRNA

NCBI chr15:85,090,150...85,170,495
Ensembl chr15:85,090,150...85,170,736

G

fibulin 5

increases expression

Selenium results in increased expression of FBLN5 mRNA

NCBI chr12:101,712,820...101,785,541
Ensembl chr12:101,712,824...101,785,314

G

fructose bisphosphatase 1

increases expression

Selenium results in increased expression of FBP1 mRNA

NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096

G

F-box and leucine-rich repeat protein 5

decreases expression

Selenium results in decreased expression of FBXL5 mRNA

NCBI chr 5:43,901,958...43,939,529
Ensembl chr 5:43,901,957...43,978,980

G

F-box and leucine-rich repeat protein 8

increases expression

Selenium results in increased expression of FBXL8 mRNA

NCBI chr 8:105,991,280...105,995,958
Ensembl chr 8:105,991,280...105,995,958

G

F-box protein 11

decreases expression

Selenium results in decreased expression of FBXO11 mRNA

NCBI chr17:88,298,287...88,373,473
Ensembl chr17:88,298,287...88,372,719

G

F-box protein 17

increases expression

Selenium results in increased expression of FBXO17 mRNA

NCBI chr 7:28,416,176...28,437,570
Ensembl chr 7:28,416,229...28,437,569

G

F-box protein 2

increases expression

Selenium results in increased expression of FBXO2 mRNA

NCBI chr 4:148,244,605...148,250,874
Ensembl chr 4:148,245,078...148,250,881

G

F-box protein 28

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FBXO28 mRNA
Selenium results in decreased expression of FBXO28 mRNA

NCBI chr 1:182,140,667...182,169,171
Ensembl chr 1:182,140,667...182,169,194

G

Fc fragment of IgG receptor and transporter

increases expression

Selenium results in increased expression of FCGRT mRNA

NCBI chr 7:44,742,417...44,753,246
Ensembl chr 7:44,742,414...44,753,275

G

farnesyl diphosphate farnesyl transferase 1

increases expression

Selenium deficiency results in increased expression of FDFT1 mRNA

NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027

G

ferrochelatase

decreases expression

Selenium results in decreased expression of FECH mRNA

NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322

G

fermitin family member 1

decreases expression

Selenium results in decreased expression of FERMT1 mRNA

NCBI chr 2:132,746,097...132,787,956
Ensembl chr 2:132,746,309...132,787,826

G

free fatty acid receptor 2

increases expression

Selenium results in increased expression of FFAR2 mRNA

NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200

G

fibrinogen gamma chain

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of FGG mRNA

NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356

G

formin homology 2 domain containing 3

decreases expression

Selenium results in decreased expression of FHOD3 mRNA

NCBI chr18:24,841,445...25,266,564
Ensembl chr18:24,841,680...25,266,558

G

FIG4 phosphoinositide 5-phosphatase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FIG4 mRNA
Selenium results in decreased expression of FIG4 mRNA

NCBI chr10:41,064,168...41,179,237
Ensembl chr10:41,064,168...41,179,256

G

fission, mitochondrial 1

increases expression

Selenium results in increased expression of FIS1 mRNA

NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088

G

FK506 binding protein 1a

increases expression
multiple interactions

Selenium results in increased expression of FKBP1A mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of FKBP1A mRNA

NCBI chr 2:151,384,403...151,403,611
Ensembl chr 2:151,384,403...151,403,612

G

FK506 binding protein 3

decreases expression

Selenium results in decreased expression of FKBP3 mRNA

NCBI chr12:65,109,206...65,120,712
Ensembl chr12:65,109,198...65,120,781

G

flightless I actin binding protein

increases expression

Selenium results in increased expression of FLII mRNA

NCBI chr11:60,604,969...60,618,089
Ensembl chr11:60,604,949...60,618,089

G

filamin, alpha

increases expression

Selenium results in increased expression of FLNA mRNA

NCBI chr X:73,267,067...73,293,787
Ensembl chr X:73,267,067...73,293,426

G

flotillin 1

increases expression

Selenium results in increased expression of FLOT1 mRNA

NCBI chr17:36,134,243...36,143,674
Ensembl chr17:36,134,122...36,143,683

G

flotillin 2

increases expression

Selenium results in increased expression of FLOT2 mRNA

NCBI chr11:77,928,757...77,951,260
Ensembl chr11:77,928,757...77,951,260

G

fibronectin leucine rich transmembrane protein 3

decreases expression

Selenium results in decreased expression of FLRT3 mRNA

NCBI chr 2:140,500,118...140,513,396
Ensembl chr 2:140,492,834...140,513,389

G

flavin containing monooxygenase 5

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of FMO5 mRNA

NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598

G

folate hydrolase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FOLH1 mRNA
Selenium results in decreased expression of FOLH1 mRNA

NCBI chr 7:86,365,733...86,425,171
Ensembl chr 7:86,368,185...86,425,151

G

FBJ osteosarcoma oncogene

increases expression
multiple interactions

Selenium results in increased expression of FOS mRNA; Selenium results in increased expression of FOS protein
[Selenium co-treated with Iodine] results in increased expression of FOS mRNA; [Selenium co-treated with Iodine] results in increased expression of FOS protein

PMID:12475444 PMID:12666833

NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047

G

forkhead box F2

decreases expression

Selenium results in decreased expression of FOXF2 mRNA

NCBI chr13:31,809,686...31,815,390
Ensembl chr13:31,809,799...31,815,386

G

forkhead box O1

multiple interactions

Selenium inhibits the reaction [arsenite results in decreased phosphorylation of FOXO1 protein]

NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642

G

forkhead box O3

multiple interactions

Selenium results in decreased phosphorylation of and results in increased activity of FOXO3 protein

NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751

G

frequently rearranged in advanced T cell lymphomas

increases expression

Selenium results in increased expression of FRAT1 mRNA

NCBI chr19:41,818,409...41,821,022
Ensembl chr19:41,818,409...41,821,022

G

follicle stimulating hormone beta

multiple interactions

Selenium inhibits the reaction [Acrylamide results in decreased expression of FSHB protein]; Selenium inhibits the reaction [Cadmium Chloride results in decreased expression of FSHB protein]

PMID:20957662 PMID:37987225

NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001

G

ferritin light polypeptide 1

increases expression

Selenium results in increased expression of FTL mRNA

NCBI chr 7:45,107,368...45,109,310
Ensembl chr 7:45,107,368...45,109,308

G

fused in sarcoma

increases expression

Selenium results in increased expression of FUS mRNA

NCBI chr 7:127,565,276...127,581,204
Ensembl chr 7:127,566,629...127,584,873

G

FMR1 autosomal homolog 1

decreases expression

Selenium results in decreased expression of FXR1 mRNA

NCBI chr 3:34,074,133...34,124,129
Ensembl chr 3:34,074,092...34,124,471

G

frizzled class receptor 7

decreases expression

Selenium results in decreased expression of FZD7 mRNA

NCBI chr 1:59,521,306...59,526,114
Ensembl chr 1:59,521,583...59,526,114

G

fizzy and cell division cycle 20 related 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of FZR1 mRNA
Selenium results in increased expression of FZR1 mRNA

NCBI chr10:81,202,713...81,214,204
Ensembl chr10:81,202,056...81,214,350

G

G0/G1 switch gene 2

increases expression

Selenium results in increased expression of G0S2 mRNA

NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525

G

growth arrest and DNA-damage-inducible 45 alpha

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GADD45A mRNA

NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441

G

polypeptide N-acetylgalactosaminyltransferase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GALNT1 mRNA
Selenium results in decreased expression of GALNT1 mRNA

NCBI chr18:24,338,401...24,419,873
Ensembl chr18:24,338,401...24,419,875

G

alpha glucosidase 2 alpha neutral subunit

increases expression

Selenium results in increased expression of GANAB mRNA

NCBI chr19:8,875,440...8,894,098
Ensembl chr19:8,875,435...8,894,036

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

Selenium results in increased expression of GAPDH mRNA

NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430

G

growth arrest specific 8

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GAS8 mRNA
Selenium results in increased expression of GAS8 mRNA

NCBI chr 8:124,245,630...124,263,394
Ensembl chr 8:124,245,573...124,263,389

G

GATA zinc finger domain containing 2A

increases expression

Selenium results in increased expression of GATAD2A mRNA

NCBI chr 8:70,359,719...70,450,093
Ensembl chr 8:70,359,726...70,449,034

G

guanylate binding protein 2b

decreases expression

Selenium results in decreased expression of GBP1 mRNA

NCBI chr 3:142,300,577...142,324,940
Ensembl chr 3:142,300,608...142,324,940

G

glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)

increases expression

Selenium results in increased expression of GCAT mRNA

NCBI chr15:78,915,074...78,926,731
Ensembl chr15:78,915,074...78,922,553
Ensembl chr15:78,915,074...78,922,553

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GCLC mRNA

NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767

G

GDP-L-fucose synthase

increases expression

Selenium results in increased expression of GFUS mRNA

NCBI chr15:75,796,532...75,801,613
Ensembl chr15:75,796,525...75,801,681

G

geranylgeranyl diphosphate synthase 1

decreases expression

Selenium results in decreased expression of GGPS1 mRNA

NCBI chr13:14,224,375...14,238,319
Ensembl chr13:14,225,244...14,238,073

G

gamma-glutamyltransferase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GGT1 mRNA
Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]

PMID:19244175 PMID:24485406

NCBI chr10:75,396,910...75,422,027
Ensembl chr10:75,397,438...75,422,034

G

GIPC PDZ domain containing family, member 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of GIPC1 mRNA
Selenium results in increased expression of GIPC1 mRNA

NCBI chr 8:84,376,037...84,391,418
Ensembl chr 8:84,379,306...84,391,323

G

gap junction protein, beta 1

increases expression

Selenium results in increased expression of GJB1 mRNA

NCBI chr X:100,419,982...100,429,235
Ensembl chr X:100,419,984...100,429,235

G

golgi apparatus protein 1

decreases expression
increases expression

Selenium results in decreased expression of GLG1 mRNA
Selenium results in increased expression of GLG1 mRNA

NCBI chr 8:111,879,916...111,985,842
Ensembl chr 8:111,881,053...111,985,848

G

GLI-Kruppel family member GLI2

increases expression

Selenium results in increased expression of GLI2 mRNA

NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349

G

glomulin, FKBP associated protein

decreases expression

Selenium results in decreased expression of GLMN mRNA

NCBI chr 5:107,696,828...107,745,754
Ensembl chr 5:107,696,833...107,745,754

G

glutaredoxin

increases expression
affects expression

Selenium deficiency results in increased expression of GLRX mRNA; Selenium results in increased expression of GLRX mRNA
Selenium affects the expression of GLRX mRNA

PMID:16170372 PMID:19351701

NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273

G

glutaredoxin 2

affects activity
affects expression

Selenium affects the activity of GLRX2 protein
Selenium affects the expression of GLRX2 protein

NCBI chr 1:143,614,787...143,625,416
Ensembl chr 1:143,592,076...143,625,414

G

glutamate dehydrogenase 1

affects expression

Selenium affects the expression of GLUD1 protein

NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222

G

predicted gene 7030

decreases expression
increases expression

Selenium results in decreased expression of HLA-F mRNA
Selenium results in increased expression of HLA-F mRNA

NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317

G

geminin

decreases expression

Selenium results in decreased expression of GMNN mRNA

NCBI chr13:24,935,828...24,954,222
Ensembl chr13:24,935,828...24,945,906

G

GDP-mannose pyrophosphorylase A

increases expression

Selenium results in increased expression of GMPPA mRNA

NCBI chr 1:75,412,555...75,419,823
Ensembl chr 1:75,412,574...75,419,823

G

guanosine monophosphate reductase 2

increases expression

Selenium results in increased expression of GMPR2 mRNA

NCBI chr14:55,909,692...55,935,602
Ensembl chr14:55,909,398...55,916,657

G

G protein subunit alpha i2

increases expression

Selenium results in increased expression of GNAI2 mRNA

NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566

G

GNAS complex locus

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GNAS mRNA
Selenium results in decreased expression of GNAS mRNA

NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537

G

guanine nucleotide binding protein (G protein), beta 2

increases expression

Selenium results in increased expression of GNB2 mRNA

NCBI chr 5:137,526,389...137,533,085
Ensembl chr 5:137,526,389...137,531,772

G

guanine nucleotide binding protein-like 1

increases expression

Selenium results in increased expression of GNL1 mRNA

NCBI chr17:36,290,847...36,300,354
Ensembl chr17:36,290,743...36,300,354

G

glycine N-methyltransferase

affects activity

Selenium affects the activity of GNMT protein

NCBI chr17:47,036,590...47,040,091
Ensembl chr17:47,036,590...47,040,094

G

glucosamine (N-acetyl)-6-sulfatase

decreases expression

Selenium results in decreased expression of GNS mRNA

NCBI chr10:121,200,995...121,233,159
Ensembl chr10:121,200,995...121,233,154

G

golgin A3

increases expression
multiple interactions

Selenium results in increased expression of GOLGA3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of GOLGA3 mRNA

NCBI chr 5:110,324,723...110,374,336
Ensembl chr 5:110,324,567...110,374,336

G

golgi reassembly stacking protein 1

increases expression

Selenium results in increased expression of GORASP1 mRNA

NCBI chr 9:119,754,739...119,766,624
Ensembl chr 9:119,754,323...119,766,631

G

golgi SNAP receptor complex member 1

decreases expression

Selenium results in decreased expression of GOSR1 mRNA

NCBI chr11:76,617,428...76,654,404
Ensembl chr11:76,617,428...76,654,405

G

glucose-6-phosphate isomerase 1

increases expression

Selenium results in increased expression of GPI mRNA

NCBI chr 7:33,900,752...33,929,761
Ensembl chr 7:33,900,755...33,929,761

G

G patch domain and KOW motifs

increases expression

Selenium results in increased expression of GPKOW mRNA

NCBI chr X:7,563,373...7,576,500
Ensembl chr X:7,563,370...7,576,501

G

G protein-coupled receptor 107

increases expression

Selenium results in increased expression of GPR107 mRNA

NCBI chr 2:31,042,099...31,106,579
Ensembl chr 2:31,042,328...31,108,787

G

G protein-coupled receptor 137

increases expression

Selenium results in increased expression of GPR137 mRNA

NCBI chr19:6,915,425...6,919,818
Ensembl chr19:6,915,425...6,919,848

G

G protein-coupled receptor 137B

decreases expression

Selenium results in decreased expression of GPR137B mRNA

NCBI chr13:13,528,035...13,568,250
Ensembl chr13:13,532,205...13,568,599

G

G protein regulated inducer of neurite outgrowth 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of GPRIN2 mRNA

NCBI chr14:33,907,645...33,923,649
Ensembl chr14:33,907,645...33,923,610

G

glutamic pyruvic transaminase, soluble

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; [Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in increased activity of GPT protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of GPT protein]; Selenium inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]

PMID:20688495 PMID:24485406 PMID:30031400 PMID:36464106 PMID:37676925

NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886

G

glutathione peroxidase 1

affects response to substance
decreases activity
increases activity
increases expression
decreases expression
multiple interactions
affects expression
affects activity

GPX1 gene polymorphism affects the susceptibility to Selenium; GPX1 protein polymorphism affects the susceptibility to Selenium
Selenium deficiency results in decreased activity of GPX1 protein
Selenium results in increased activity of GPX1 protein
Selenium results in increased expression of GPX1 mRNA; Selenium results in increased expression of GPX1 protein
Selenium deficiency results in decreased expression of GPX1 mRNA; Selenium deficiency results in decreased expression of GPX1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GPX1 mRNA; Selenium inhibits the reaction [2-iodohexadecanal results in decreased expression of GPX1 mRNA]; Selenium inhibits the reaction [arsenite results in decreased expression of GPX1 protein]; Selenium inhibits the reaction [Cisplatin results in decreased expression of GPX1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of GPX1 mRNA]; Selenium results in increased expression of and results in decreased degradation of GPX1 mRNA
Selenium affects the expression of GPX1 mRNA
Selenium affects the activity of GPX1 protein
Selenium deficiency inhibits the reaction [IL4 protein results in increased expression of GPX1 protein]; Selenium deficiency inhibits the reaction [Lipopolysaccharides results in increased expression of GPX1 protein]; Selenium deficiency results in decreased expression of and results in decreased activity of GPX1 protein
Selenium affects the expression of GPX1 mRNA; Selenium affects the expression of GPX1 protein

PMID:10874123 PMID:10949970 PMID:11294903 PMID:11444866 PMID:11463357 More...

NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542

G

glutathione peroxidase 2

decreases activity
decreases expression

Selenium deficiency results in decreased activity of GPX2 protein
Selenium deficiency results in decreased expression of GPX2 mRNA

NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273

G

glutathione peroxidase 3

increases expression
affects activity
increases activity
affects expression

Selenium results in increased expression of GPX3 mRNA
Selenium affects the activity of GPX3 protein
Selenium results in increased activity of GPX3 protein
Selenium affects the expression of GPX3 mRNA

PMID:15894816 PMID:19022953 PMID:19106321 PMID:19244175 PMID:19351701

NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203

G

glutathione peroxidase 4

increases activity
multiple interactions
decreases expression
increases expression
decreases activity
affects activity
decreases abundance

Selenium analog results in increased activity of GPX4 protein
Selenomethionine inhibits the reaction [Selenium deficiency results in decreased expression of GPX4 protein]; Sodium Selenite inhibits the reaction [Selenium deficiency results in decreased expression of GPX4 protein]
[2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in increased expression of GPX4 protein
Selenium deficiency results in decreased expression of GPX4 mRNA
Selenium results in increased expression of GPX4 mRNA
Selenium deficiency results in decreased activity of GPX4 protein
Selenium affects the activity of GPX4 protein
Selenium results in increased activity of GPX4 protein
GPX4 gene mutant form results in decreased abundance of Selenium
Selenium results in increased expression of and results in increased activity of GPX4 protein
Selenium results in increased expression of GPX4 mRNA; Selenium results in increased expression of GPX4 protein

PMID:11673642 PMID:12031252 PMID:15670848 PMID:15792362 PMID:16246897 More...

NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273

G

glutathione peroxidase 5

affects expression

Selenium affects the expression of GPX5

NCBI chr13:21,470,599...21,476,897
Ensembl chr13:21,470,599...21,476,901

G

glutamate receptor, ionotropic, AMPA2 (alpha 2)

decreases expression

Selenium results in decreased expression of GRIA2 mRNA

NCBI chr 3:80,588,757...80,711,534
Ensembl chr 3:80,588,757...80,710,142

G

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GRINA mRNA
Selenium results in increased expression of GRINA mRNA

NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104

G

G protein-coupled receptor kinase 6

increases expression

Selenium results in increased expression of GRK6 mRNA

NCBI chr13:55,592,865...55,608,740
Ensembl chr13:55,592,885...55,608,740

G

granulin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of GRN mRNA
Selenium results in increased expression of GRN mRNA

NCBI chr11:102,321,333...102,327,635
Ensembl chr11:102,321,141...102,327,874

G

gasdermin E

decreases expression

Selenium results in decreased expression of GSDME mRNA

NCBI chr 6:50,167,013...50,240,837
Ensembl chr 6:50,165,868...50,240,842

G

glycogen synthase kinase 3 alpha

increases expression

Selenium results in increased expression of GSK3A mRNA

NCBI chr 7:24,927,683...24,937,276
Ensembl chr 7:24,927,683...24,937,276

G

glycogen synthase kinase 3 beta

multiple interactions
decreases phosphorylation
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA; Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]
Selenium results in decreased phosphorylation of GSK3B protein
Selenium results in decreased expression of GSK3B mRNA

PMID:17339365 PMID:19244175

NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446

G

gelsolin

increases expression

Selenium results in increased expression of GSN mRNA

NCBI chr 2:35,146,371...35,197,914
Ensembl chr 2:35,146,392...35,197,904

G

glutathione reductase

multiple interactions

Selenium inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

glutathione S-transferase, alpha 1 (Ya)

increases expression

Selenium deficiency results in increased expression of GSTA5 mRNA; Selenium deficiency results in increased expression of GSTA5 protein

NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966

G

glutathione S-transferase, alpha 3

increases expression

Selenium deficiency results in increased expression of GSTA2 mRNA; Selenium results in increased expression of GSTA2 mRNA

NCBI chr 1:21,310,837...21,335,885
Ensembl chr 1:21,310,813...21,335,885

G

glutathione S-transferase, pi 1

multiple interactions
increases expression
affects expression

[Selenium co-treated with Vitamin E] results in decreased expression of GSTP1 mRNA
Selenium results in increased expression of GSTP1 mRNA
Selenium affects the expression of GSTP1 protein

PMID:7532609 PMID:19244175

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, theta 1

increases expression

Selenium deficiency results in increased expression of GSTT1

NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418

G

general transcription factor IIF, polypeptide 1

increases expression

Selenium results in increased expression of GTF2F1 mRNA

NCBI chr17:57,310,402...57,318,398
Ensembl chr17:57,310,405...57,318,288

G

general transcription factor III C 1

increases expression

Selenium results in increased expression of GTF3C1 mRNA

NCBI chr 7:125,240,126...125,306,860
Ensembl chr 7:125,240,126...125,306,952

G

GTP-binding protein 8 (putative)

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GTPBP8 mRNA
Selenium results in decreased expression of GTPBP8 mRNA

NCBI chr16:44,559,242...44,566,726
Ensembl chr16:44,557,131...44,566,726

G

GULP, engulfment adaptor PTB domain containing 1

decreases expression

Selenium results in decreased expression of GULP1 mRNA

NCBI chr 1:44,590,540...44,835,998
Ensembl chr 1:44,590,671...44,835,998

G

histocompatibility 2, class II antigen A, beta 1

increases expression

Selenium results in increased expression of HLA-DQB1 mRNA

NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393

G

histocompatibility 2, class II antigen E alpha

increases expression

Selenium results in increased expression of HLA-DRA mRNA

NCBI chr17:34,560,926...34,563,619
Ensembl chr17:34,560,926...34,563,618

G

histocompatibility 2, M region locus 2

increases expression

Selenium results in increased expression of HLA-B mRNA

NCBI chr17:37,791,742...37,794,445
Ensembl chr17:37,791,742...37,794,443

G

histocompatibility 2, M region locus 3

increases expression

Selenium results in increased expression of HLA-G mRNA

NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375

G

histocompatibility 2, P region alpha locus

increases expression

Selenium results in increased expression of HLA-DPA1 mRNA

NCBI chr17:34,303,587...34,304,826
Ensembl chr17:34,303,575...34,304,797

G

histocompatibility 2, T region locus 23

increases expression

Selenium results in increased expression of HLA-E mRNA

NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747

G

H2A.X variant histone

increases expression
multiple interactions

Selenium results in increased expression of H2AX mRNA
Selenium inhibits the reaction [Acrylamide results in increased expression of H2AX protein]

PMID:19244175 PMID:37987225

NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374

G

H3.3 histone A

decreases expression

Selenium results in decreased expression of H3-3A mRNA

NCBI chr 1:180,630,125...180,641,127
Ensembl chr 1:180,628,397...180,641,508

G

H4 clustered histone 3

decreases expression

Selenium results in decreased expression of H4C6 mRNA

NCBI chr13:23,882,067...23,882,441
Ensembl chr13:23,881,618...23,882,437

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of H6PD mRNA
Selenium results in increased expression of H6PD mRNA

NCBI chr 4:150,063,931...150,093,480
Ensembl chr 4:150,063,932...150,093,480

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

Selenium results in decreased expression of HADHA mRNA

NCBI chr 5:30,324,421...30,359,978
Ensembl chr 5:30,323,302...30,360,160

G

hydroxyacyl glutathione hydrolase

increases expression

Selenium results in increased expression of HAGH mRNA

NCBI chr17:25,056,863...25,083,424
Ensembl chr17:25,059,117...25,083,424

G

histidyl-tRNA synthetase 1

increases expression

Selenium results in increased expression of HARS1 mRNA

NCBI chr18:36,899,581...36,916,258
Ensembl chr18:36,899,581...36,916,258

G

HAUS augmin-like complex, subunit 3

decreases expression
multiple interactions

Selenium results in decreased expression of HAUS3 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of HAUS3 mRNA

NCBI chr 5:34,311,240...34,326,768
Ensembl chr 5:34,311,224...34,326,871

G

HAUS augmin-like complex, subunit 4

increases expression

Selenium results in increased expression of HAUS4 mRNA

NCBI chr14:54,779,242...54,792,446
Ensembl chr14:54,779,242...54,792,073

G

hemoglobin alpha, adult chain 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of HBA2 mRNA

NCBI chr11:32,246,492...32,247,310
Ensembl chr11:32,246,489...32,247,298

G

heparin binding growth factor

increases expression

Selenium results in increased expression of HDGF mRNA

NCBI chr 3:87,813,844...87,823,439
Ensembl chr 3:87,813,628...87,823,439

G

high density lipoprotein (HDL) binding protein

increases expression

Selenium results in increased expression of HDLBP mRNA

NCBI chr 1:93,333,662...93,406,639
Ensembl chr 1:93,333,662...93,406,537

G

hephaestin

decreases expression

Selenium results in decreased expression of HEPH mRNA

NCBI chr X:95,499,042...95,618,091
Ensembl chr X:95,498,965...95,618,091

G

hes family bHLH transcription factor 1

decreases expression
multiple interactions

Selenium results in decreased expression of HES1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of HES1 mRNA

NCBI chr16:29,883,259...29,886,614
Ensembl chr16:29,883,202...29,886,614

G

HGF-regulated tyrosine kinase substrate

increases expression

Selenium results in increased expression of HGS mRNA

NCBI chr11:120,358,431...120,374,810
Ensembl chr11:120,358,461...120,374,805

G

Hedgehog-interacting protein

increases expression

Selenium results in increased expression of HHIP mRNA

NCBI chr 8:80,692,480...80,784,637
Ensembl chr 8:80,692,480...80,784,635

G

huntingtin interacting protein 1 related

increases expression

Selenium results in increased expression of HIP1R mRNA

NCBI chr 5:124,111,665...124,141,263
Ensembl chr 5:124,111,691...124,143,621

G

homeodomain interacting protein kinase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HIPK2 mRNA
Selenium results in decreased expression of HIPK2 mRNA

NCBI chr 6:38,664,447...38,853,236
Ensembl chr 6:38,671,325...38,853,099

G

HIRA interacting protein 3

increases expression

Selenium results in increased expression of HIRIP3 mRNA

NCBI chr 7:126,461,155...126,464,549
Ensembl chr 7:126,461,144...126,464,549

G

hepatic leukemia factor

decreases expression

Selenium results in decreased expression of HLF mRNA

NCBI chr11:90,227,361...90,281,745
Ensembl chr11:90,227,362...90,281,721

G

hydroxymethylbilane synthase

increases expression

Selenium results in increased expression of HMBS mRNA

NCBI chr 9:44,247,645...44,255,525
Ensembl chr 9:44,247,636...44,255,525

G

high mobility group box 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of HMGB1 mRNA

NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299

G

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Selenium promotes the reaction [Cholesterol results in decreased expression of HMGCR mRNA]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]

PMID:16581047 PMID:30031400 PMID:36464106

NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444

G

HMG box domain containing 3

increases expression

Selenium results in increased expression of HMGXB3 mRNA

NCBI chr18:61,264,349...61,310,122
Ensembl chr18:61,264,349...61,310,122

G

HMG box domain containing 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HMGXB4 mRNA
Selenium results in decreased expression of HMGXB4 mRNA

NCBI chr 8:75,720,305...75,758,606
Ensembl chr 8:75,719,984...75,758,606

G

heme oxygenase 1

multiple interactions
increases expression
affects expression
affects activity

[Arsenic co-treated with Selenium] results in increased expression of HMOX1 mRNA; [Arsenic co-treated with Selenium] results in increased expression of HMOX1 protein; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] affects the expression of HMOX1 mRNA; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of HMOX1 mRNA
Selenium deficiency results in increased expression of HMOX1 mRNA
Phenobarbital promotes the reaction [Selenium deficiency results in increased expression of and results in increased activity of HMOX1 protein]; Phenobarbital promotes the reaction [Selenium deficiency results in increased expression of HMOX1 mRNA]; Selenium deficiency results in increased expression of and results in increased activity of HMOX1 protein; Selenium inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein]
Selenium affects the expression of HMOX1 protein
Selenium affects the activity of HMOX1 protein
NFE2L2 protein affects the reaction [Selenium affects the activity of HMOX1 protein]
Selenium results in increased expression of HMOX1 mRNA; Selenium results in increased expression of HMOX1 protein

PMID:12751798 PMID:16837816 PMID:18279678 PMID:20478284 PMID:21481475

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

H6 homeobox 1

increases expression

Selenium results in increased expression of HMX1 mRNA

NCBI chr 5:35,546,124...35,557,629
Ensembl chr 5:35,546,452...35,557,074

G

HNF1 homeobox B

increases expression

Selenium results in increased expression of HNF1B mRNA

NCBI chr11:83,741,035...83,796,743
Ensembl chr11:83,740,889...83,796,645

G

histamine N-methyltransferase

decreases expression
multiple interactions

Selenium results in decreased expression of HNMT mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HNMT mRNA

NCBI chr 2:23,892,923...23,939,756
Ensembl chr 2:23,892,922...23,939,406

G

heterogeneous nuclear ribonucleoprotein D

increases expression

Selenium results in increased expression of HNRNPD mRNA

NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797

G

heterogeneous nuclear ribonucleoprotein M

increases expression

Selenium results in increased expression of HNRNPM mRNA

NCBI chr17:33,865,207...33,904,432
Ensembl chr17:33,865,207...33,905,834

G

homer scaffolding protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of HOMER1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HOMER1 mRNA

NCBI chr13:93,440,265...93,549,471
Ensembl chr13:93,436,143...93,541,637

G

hook microtubule tethering protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HOOK1 mRNA
Selenium results in decreased expression of HOOK1 mRNA

NCBI chr 4:95,855,418...95,913,649
Ensembl chr 4:95,855,477...95,913,650

G

hippocalcin-like 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HPCAL1 mRNA
Selenium results in increased expression of HPCAL1 mRNA

NCBI chr12:17,740,810...17,841,943
Ensembl chr12:17,740,857...17,841,934

G

hematopoietic prostaglandin D synthase

multiple interactions

[Selenium deficiency co-treated with 4-(benzo(b)thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one co-treated with Lipopolysaccharides] results in increased expression of HPGDS mRNA; [Selenium deficiency co-treated with 4-(benzo(b)thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one co-treated with Lipopolysaccharides] results in increased expression of HPGDS protein; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in increased expression of HPGDS mRNA; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in increased expression of HPGDS protein; [Selenium deficiency co-treated with rosiglitazone] results in increased expression of HPGDS protein

NCBI chr 6:65,094,019...65,121,960
Ensembl chr 6:65,094,277...65,121,892

G

hepsin

increases expression

Selenium results in increased expression of HPN mRNA

NCBI chr 7:30,798,150...30,814,751
Ensembl chr 7:30,798,150...30,814,715

G

Harvey rat sarcoma virus oncogene

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of HRAS mRNA
Selenium results in increased expression of HRAS mRNA

NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918

G

heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1

decreases expression

Selenium results in decreased expression of HS3ST3A1 mRNA

NCBI chr11:64,326,158...64,413,667
Ensembl chr11:64,326,158...64,413,667

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein]; [Sodium Selenite results in increased abundance of Selenium] which results in increased expression of HSD11B2 protein

PMID:11444866 PMID:35384129

NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620

G

hydroxysteroid (17-beta) dehydrogenase 11

increases expression

Selenium deficiency results in increased expression of HSD17B11 mRNA; Selenium results in increased expression of HSD17B11 mRNA

NCBI chr 5:104,137,631...104,169,662
Ensembl chr 5:104,137,628...104,169,785

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions

Selenium inhibits the reaction [Acrylamide results in decreased expression of HSD17B3 mRNA]

NCBI chr13:64,206,088...64,237,076
Ensembl chr13:64,206,080...64,237,044

G

hydroxysteroid 17-beta dehydrogenase 8

increases expression

Selenium results in increased expression of HSD17B8 mRNA

NCBI chr17:34,245,007...34,247,029
Ensembl chr17:34,245,007...34,247,034

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

increases expression

Selenium deficiency results in increased expression of HSD3B2 mRNA; Selenium results in increased expression of HSD3B2 mRNA

NCBI chr 3:98,749,672...98,767,110
Ensembl chr 3:98,759,510...98,767,110

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5

increases expression

Selenium deficiency results in increased expression of HSD3B5 mRNA; Selenium results in increased expression of HSD3B5 mRNA

NCBI chr 3:98,525,952...98,552,850
Ensembl chr 3:98,525,950...98,537,568

G

heat shock protein 90, alpha (cytosolic), class A member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HSP90AA1 mRNA
Selenium results in decreased expression of HSP90AA1 mRNA

NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162

G

heat shock protein 90 alpha (cytosolic), class B member 1

increases expression

Selenium results in increased expression of HSP90AB1 mRNA

NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197

G

heat shock protein 90, beta (Grp94), member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HSP90B1 mRNA
Selenium results in decreased expression of HSP90B1 mRNA

NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373

G

heat shock protein 1A

multiple interactions
increases expression

[Selenium co-treated with Fluorides] results in increased expression of HSPA1A mRNA; Fluorides promotes the reaction [Selenium results in increased expression of HSPA1A protein]
Selenium results in increased expression of HSPA1A mRNA; Selenium results in increased expression of HSPA1A protein

PMID:19244175 PMID:19652462

NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132

G

heat shock protein 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of HSPA4 mRNA

NCBI chr11:53,150,641...53,191,306
Ensembl chr11:53,150,641...53,191,284

G

heat shock protein 9

decreases expression
multiple interactions

Selenium results in decreased expression of HSPA9 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HSPA9 mRNA

NCBI chr18:35,070,467...35,087,404
Ensembl chr18:35,070,467...35,087,410

G

heat shock protein 1

increases expression

Selenium results in increased expression of HSPB1 mRNA

NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417

G

heat shock protein 2

decreases expression

Selenium results in decreased expression of HSPB2 mRNA

NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654

G

Hspb associated protein 1

decreases expression

Selenium results in decreased expression of HSPBAP1 mRNA

NCBI chr16:35,590,009...35,648,832
Ensembl chr16:35,590,745...35,648,847

G

5 hydroxytryptamine (serotonin) receptor 4

increases expression

Selenium results in increased expression of HTR4 mRNA

NCBI chr18:62,456,618...62,636,098
Ensembl chr18:62,457,275...62,629,648

G

isoleucyl-tRNA synthetase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IARS1 mRNA
Selenium results in decreased expression of IARS1 mRNA

NCBI chr13:49,835,606...49,887,743
Ensembl chr13:49,835,576...49,887,743

G

islet cell autoantigen 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ICA1 mRNA
Selenium results in increased expression of ICA1 mRNA

NCBI chr 6:8,630,527...8,778,531
Ensembl chr 6:8,630,527...8,778,488

G

inhibitor of DNA binding 1, HLH protein

increases expression

Selenium results in increased expression of ID1 mRNA

NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330

G

inhibitor of DNA binding 2

decreases expression

Selenium results in decreased expression of ID2 mRNA

NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139

G

isocitrate dehydrogenase 3 (NAD+) beta

increases expression

Selenium results in increased expression of IDH3B mRNA

NCBI chr 2:130,121,229...130,126,371
Ensembl chr 2:130,121,229...130,126,467

G

isocitrate dehydrogenase 3 (NAD+), gamma

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of IDH3G mRNA
Selenium results in increased expression of IDH3G mRNA

NCBI chr X:72,822,569...72,830,471
Ensembl chr X:72,822,569...72,830,503

G

iduronidase, alpha-L

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of IDUA mRNA
Selenium results in increased expression of IDUA mRNA

NCBI chr 5:108,808,197...108,833,312
Ensembl chr 5:108,808,197...108,832,423

G

immediate early response 3

increases expression

Selenium results in increased expression of IER3 mRNA

NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815

G

interferon-induced protein 35

increases expression

Selenium results in increased expression of IFI35 mRNA

NCBI chr11:101,339,238...101,349,527
Ensembl chr11:101,339,233...101,349,524

G

interferon induced transmembrane protein 1

increases expression

Selenium results in increased expression of IFITM1 mRNA

NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738

G

interferon induced transmembrane protein 2

increases expression

Selenium results in increased expression of IFITM2 mRNA

NCBI chr 7:140,534,750...140,539,602
Ensembl chr 7:140,534,750...140,535,900

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interferon induced transmembrane protein 3

increases expression

Selenium results in increased expression of IFITM3 mRNA

NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683

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interferon alpha 1

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] affects the expression of IFNA1 mRNA

NCBI chr 4:88,768,324...88,768,893
Ensembl chr 4:88,768,324...88,768,893

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interferon gamma

decreases expression

Selenium results in decreased expression of IFNG protein

NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797

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interferon-related developmental regulator 2

increases expression

Selenium results in increased expression of IFRD2 mRNA

NCBI chr 9:107,464,917...107,470,237
Ensembl chr 9:107,464,841...107,470,584

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intraflagellar transport 74

decreases expression
multiple interactions

Selenium results in decreased expression of IFT74 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of IFT74 mRNA

NCBI chr 4:94,491,503...94,581,470
Ensembl chr 4:94,502,728...94,581,466

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intraflagellar transport 81

decreases expression

Selenium results in decreased expression of IFT81 mRNA

NCBI chr 5:122,678,328...122,752,614
Ensembl chr 5:122,688,267...122,752,581

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insulin-like growth factor 2 receptor

decreases expression

Selenium results in decreased expression of IGF2R mRNA

NCBI chr17:12,901,293...12,988,593
Ensembl chr17:12,901,293...12,988,551

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insulin-like growth factor binding protein 2

increases expression

Selenium results in increased expression of IGFBP2 mRNA

NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633

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insulin-like growth factor binding protein 3

increases expression

Selenium results in increased expression of IGFBP3 mRNA; Selenium results in increased expression of IGFBP3 protein

PMID:15318950 PMID:18997278

NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923

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insulin-like growth factor binding protein 4

increases expression

Selenium results in increased expression of IGFBP4 mRNA

NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218

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insulin-like growth factor binding protein 6

increases expression

Selenium results in increased expression of IGFBP6 mRNA

NCBI chr15:102,052,621...102,057,947
Ensembl chr15:102,052,797...102,057,946

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immunoglobulin heavy constant mu

increases expression

Selenium results in increased expression of IGHM mRNA

NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350

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IK cytokine

increases expression

Selenium results in increased expression of IK mRNA

NCBI chr18:36,877,709...36,890,692
Ensembl chr18:36,877,731...36,890,688

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inhibitor of kappaB kinase beta

multiple interactions

Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of IKBKB protein]
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IKBKB mRNA

PMID:17439952 PMID:21481475

NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605

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interleukin 10

multiple interactions

[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL10 protein]
[Drugs, Chinese Herbal co-treated with Selenium] results in increased expression of IL10 mRNA
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL10 mRNA; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL10 mRNA

PMID:15862027 PMID:21481475 PMID:24626144 PMID:26089086

NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711

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interleukin 17 receptor C

increases expression

Selenium results in increased expression of IL17RC mRNA

NCBI chr 6:113,448,416...113,460,124
Ensembl chr 6:113,448,388...113,460,101

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interleukin 1 beta

multiple interactions
increases expression

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL1B mRNA; Selenium affects the reaction [IL1B protein results in increased abundance of Hydrogen Peroxide]; Selenium inhibits the reaction [IL1B protein results in increased abundance of Hydrogen Peroxide]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]
Selenium inhibits the reaction [Acrylamide results in increased expression of IL1B protein]
Selenium deficiency results in increased expression of IL1B mRNA
[Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of IL1B mRNA; Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
Selenium results in increased expression of IL1B mRNA

PMID:10802230 PMID:17293063 PMID:17630198 PMID:18196609 PMID:21481475 More...

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

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interleukin 1 receptor, type II

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1R2 mRNA

NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391

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interleukin 1 receptor accessory protein-like 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RAPL2 mRNA

NCBI chr X:136,471,503...137,749,826
Ensembl chr X:136,471,357...137,747,695

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interleukin 1 receptor-like 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RL2 mRNA

NCBI chr 1:40,363,697...40,406,722
Ensembl chr 1:40,363,770...40,406,722

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interleukin 1 receptor antagonist

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RN mRNA

NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506

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interleukin 2

affects expression

Selenium affects the expression of IL2 protein

NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108

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interleukin 4

decreases expression
multiple interactions

Selenium results in decreased expression of IL4 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA]; 4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; [Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein; [Selenium co-treated with IL4 protein] results in increased expression of ARG1 mRNA; [Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of IL1B mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of TNF mRNA; leflunomide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; rosiglitazone promotes the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; Selenium deficiency inhibits the reaction [IL4 protein results in increased expression of GPX1 protein]
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] results in increased expression of IL4 protein

PMID:14624943 PMID:15862027 PMID:21775527

NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496

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interleukin 4 receptor, alpha

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IL4R mRNA
Selenium results in increased expression of IL4R mRNA

NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646

G

interleukin 6

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL6 mRNA
[Selenium co-treated with Zinc] inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL6 protein]; Selenium inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Arsenic] results in increased expression of IL6 protein]; Selenium inhibits the reaction [Acrylamide results in increased expression of IL6 protein]

PMID:21481475 PMID:26089086 PMID:37676925 PMID:37987225

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

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interleukin 6 signal transducer

de